Sites and mechanisms of aconitase inactivation by peroxynitrite: Modulation by citrate and glutathione

Biochemistry

Volumn 44, Issue 36, 2005, Pages 11986-11996

  Han, Derick ^a   Canali, Raffaella ^b   Garcia, Jerome ^c   Aguilera, Rodrigo ^c   Gallaher, Timothy K ^c   Cadenas, Enrique ^c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; ENZYMES; METABOLISM; NITRATION; OXIDATION; PARAMAGNETIC RESONANCE;

ACONITASE INACTIVATION; CITRATE; MITOCHONDRIA; TYROSINE NITRATION;

IRON COMPOUNDS;

ACONITATE HYDRATASE; CITRIC ACID; CUBANE DERIVATIVE; CYSTEINE; GLUTATHIONE; IRON; NITRIC OXIDE; OXIDIZING AGENT; PEROXYNITRITE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SULFONIC ACID DERIVATIVE; SULFUR; SUPEROXIDE; THIOL; TYROSINE;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CYTOSOL; ELECTRON SPIN RESONANCE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INACTIVATION; ENZYME SUBSTRATE COMPLEX; LIQUID CHROMATOGRAPHY; LOW TEMPERATURE; MITOCHONDRION; NITRATION; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; REACTION ANALYSIS; S GLUTATHIONYLATION; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

ACONITATE HYDRATASE; AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; CITRIC ACID; CYSTEINE; ENZYME ACTIVATION; GLUTATHIONE; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MYOCARDIUM; PEROXYNITROUS ACID; SWINE; TYROSINE;

EID: 24644469955     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0509393     Document Type: Article

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