-
1
-
-
0242585476
-
Asymmetric inheritance of oxidatively damaged proteins during cytokinesis
-
Aguilaniu H., Gustafsson L., Rigoulet M., and Nystrom T. Asymmetric inheritance of oxidatively damaged proteins during cytokinesis. Science 299 (2003) 1751-1753
-
(2003)
Science
, vol.299
, pp. 1751-1753
-
-
Aguilaniu, H.1
Gustafsson, L.2
Rigoulet, M.3
Nystrom, T.4
-
3
-
-
25144510360
-
Antioxidants do not explain the disparate longevity between mice and the longest-living rodent, the naked mole-rat
-
Andziak B., O'Connor T.P., and Buffenstein R. Antioxidants do not explain the disparate longevity between mice and the longest-living rodent, the naked mole-rat. Mech. Ageing Dev. 126 (2005) 1206-1212
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 1206-1212
-
-
Andziak, B.1
O'Connor, T.P.2
Buffenstein, R.3
-
4
-
-
33751242066
-
High oxidative damage levels in the longest-living rodent, the naked mole-rat
-
Andziak B., O'Connor T.P., Qi W., DeWaal E.M., Pierce A., Chaudhuri A.R., Van Remmen H., and Buffenstein R. High oxidative damage levels in the longest-living rodent, the naked mole-rat. Aging Cell 5 (2006) 463-471
-
(2006)
Aging Cell
, vol.5
, pp. 463-471
-
-
Andziak, B.1
O'Connor, T.P.2
Qi, W.3
DeWaal, E.M.4
Pierce, A.5
Chaudhuri, A.R.6
Van Remmen, H.7
Buffenstein, R.8
-
5
-
-
34848911606
-
Genetics of aging in Caenorhabditis elegans
-
Antebi A. Genetics of aging in Caenorhabditis elegans. PLoS Genet. 3 (2007) e129
-
(2007)
PLoS Genet.
, vol.3
-
-
Antebi, A.1
-
7
-
-
33644551216
-
Current strategies for the treatment of hereditary tyrosinemia type I
-
Ashorn M., Pitkanen S., Salo M.K., and Heikinheimo M. Current strategies for the treatment of hereditary tyrosinemia type I. Pediatr. Drugs 8 (2006) 47-54
-
(2006)
Pediatr. Drugs
, vol.8
, pp. 47-54
-
-
Ashorn, M.1
Pitkanen, S.2
Salo, M.K.3
Heikinheimo, M.4
-
8
-
-
0027384878
-
Retarded senescence in an insular population of Virginia opossums (Didelphis virginiana)
-
Austad S.N. Retarded senescence in an insular population of Virginia opossums (Didelphis virginiana). J. Zool. 229 (1993) 695-708
-
(1993)
J. Zool.
, vol.229
, pp. 695-708
-
-
Austad, S.N.1
-
9
-
-
13844249825
-
Is aging programed?
-
Austad S.N. Is aging programed?. Aging Cell 3 (2004) 249-251
-
(2004)
Aging Cell
, vol.3
, pp. 249-251
-
-
Austad, S.N.1
-
10
-
-
1542541483
-
Are mice calorically restricted in nature?
-
Austad S.N., and Kristan D.M. Are mice calorically restricted in nature?. Aging Cell 2 (2003) 201-207
-
(2003)
Aging Cell
, vol.2
, pp. 201-207
-
-
Austad, S.N.1
Kristan, D.M.2
-
11
-
-
38349093613
-
Remarkable longevity and stress resistance of nematode PI3K-null mutants
-
Ayyadevara S., Alla R., Thaden J.J., and Shmookler Reis R.J. Remarkable longevity and stress resistance of nematode PI3K-null mutants. Aging Cell 7 (2008) 13-22
-
(2008)
Aging Cell
, vol.7
, pp. 13-22
-
-
Ayyadevara, S.1
Alla, R.2
Thaden, J.J.3
Shmookler Reis, R.J.4
-
12
-
-
33644823205
-
Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2
-
Ayyadevara S., Dandapat A., Singh S.P., Beneš H., Zimniak L., Shmookler Reis R.J., and Zimniak P. Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2. Aging Cell 4 (2005) 299-307
-
(2005)
Aging Cell
, vol.4
, pp. 299-307
-
-
Ayyadevara, S.1
Dandapat, A.2
Singh, S.P.3
Beneš, H.4
Zimniak, L.5
Shmookler Reis, R.J.6
Zimniak, P.7
-
13
-
-
27744580715
-
Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal
-
Ayyadevara S., Engle M.R., Singh S.P., Dandapat A., Lichti C.F., Beneš H., Shmookler Reis R.J., Liebau E., and Zimniak P. Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal. Aging Cell 4 (2005) 257-271
-
(2005)
Aging Cell
, vol.4
, pp. 257-271
-
-
Ayyadevara, S.1
Engle, M.R.2
Singh, S.P.3
Dandapat, A.4
Lichti, C.F.5
Beneš, H.6
Shmookler Reis, R.J.7
Liebau, E.8
Zimniak, P.9
-
14
-
-
33846206430
-
Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal
-
Ayyadevara S., Dandapat A., Singh S.P., Siegel E.R., Shmookler Reis R.J., Zimniak L., and Zimniak P. Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal. Mech. Ageing Dev. 128 (2007) 196-205
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 196-205
-
-
Ayyadevara, S.1
Dandapat, A.2
Singh, S.P.3
Siegel, E.R.4
Shmookler Reis, R.J.5
Zimniak, L.6
Zimniak, P.7
-
16
-
-
33845901254
-
Physiology: obesity and gut flora
-
Bajzer M., and Seeley R.J. Physiology: obesity and gut flora. Nature 444 (2006) 1009-1010
-
(2006)
Nature
, vol.444
, pp. 1009-1010
-
-
Bajzer, M.1
Seeley, R.J.2
-
17
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban R.S., Nemoto S., and Finkel T. Mitochondria, oxidants, and aging. Cell 120 (2005) 483-495
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
18
-
-
4544322045
-
Free radicals and aging
-
Barja G. Free radicals and aging. Trends Neurosci. 27 (2004) 595-600
-
(2004)
Trends Neurosci.
, vol.27
, pp. 595-600
-
-
Barja, G.1
-
19
-
-
39749147206
-
Lipid peroxidation: control of cell proliferation, cell differentiation and cell death
-
Barrera G., Pizzimenti S., and Dianzani M.U. Lipid peroxidation: control of cell proliferation, cell differentiation and cell death. Mol. Aspects Med. 29 (2008) 1-8
-
(2008)
Mol. Aspects Med.
, vol.29
, pp. 1-8
-
-
Barrera, G.1
Pizzimenti, S.2
Dianzani, M.U.3
-
20
-
-
43449083772
-
Impact of reduced IGF-1/insulin signaling on aging in mammals: novel findings
-
Bartke A. Impact of reduced IGF-1/insulin signaling on aging in mammals: novel findings. Aging Cell 7 (2008) 285-290
-
(2008)
Aging Cell
, vol.7
, pp. 285-290
-
-
Bartke, A.1
-
21
-
-
20444398158
-
Hamilton's indicators of the force of selection
-
Baudisch A. Hamilton's indicators of the force of selection. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 8263-8268
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 8263-8268
-
-
Baudisch, A.1
-
22
-
-
53049084866
-
-
Baudisch, A., 2008. Inevitable Aging?: Contributions to Evolutionary-demographic Theory. Springer, Berlin. http://www.springer.com/economics/population/book/978-3-540-76655-1; http://www.demogr.mpg.de/books/drm/004/.
-
Baudisch, A., 2008. Inevitable Aging?: Contributions to Evolutionary-demographic Theory. Springer, Berlin. http://www.springer.com/economics/population/book/978-3-540-76655-1; http://www.demogr.mpg.de/books/drm/004/.
-
-
-
-
23
-
-
0036591866
-
Effects of superoxide dismutase/catalase mimetics on life span and oxidative stress resistance in the housefly Musca domestica
-
Bayne A.C.V., and Sohal R.S. Effects of superoxide dismutase/catalase mimetics on life span and oxidative stress resistance in the housefly Musca domestica. Free Radic. Biol. Med. 32 (2002) 1229-1234
-
(2002)
Free Radic. Biol. Med.
, vol.32
, pp. 1229-1234
-
-
Bayne, A.C.V.1
Sohal, R.S.2
-
24
-
-
0034893715
-
The role of AGEs in aging: causation or correlation
-
Baynes J.W. The role of AGEs in aging: causation or correlation. Exp. Gerontol. 36 (2001) 1527-1537
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 1527-1537
-
-
Baynes, J.W.1
-
25
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman K.B., and Ames B.N. The free radical theory of aging matures. Physiol. Rev. 78 (1998) 547-581
-
(1998)
Physiol. Rev.
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
26
-
-
35948982621
-
The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction
-
Bergamini E., Cavallini G., Donati A., and Gori Z. The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction. Ann. NY Acad. Sci. 1114 (2007) 69-78
-
(2007)
Ann. NY Acad. Sci.
, vol.1114
, pp. 69-78
-
-
Bergamini, E.1
Cavallini, G.2
Donati, A.3
Gori, Z.4
-
27
-
-
4344658994
-
Fisheries sustainability via protection of age structure and spatial distribution of fish populations
-
Berkeley S.A., Hixon M.A., Larson R.J., and Love M.S. Fisheries sustainability via protection of age structure and spatial distribution of fish populations. Fisheries 29 (2004) 23-32
-
(2004)
Fisheries
, vol.29
, pp. 23-32
-
-
Berkeley, S.A.1
Hixon, M.A.2
Larson, R.J.3
Love, M.S.4
-
28
-
-
0027009447
-
Life history and bioeconomy of the house mouse
-
Berry R.J., and Bronson F.H. Life history and bioeconomy of the house mouse. Biol. Rev. 67 (1992) 519-550
-
(1992)
Biol. Rev.
, vol.67
, pp. 519-550
-
-
Berry, R.J.1
Bronson, F.H.2
-
29
-
-
33846813359
-
Uncoupling protein-3: clues in an ongoing mitochondrial mystery
-
Bezaire V., Seifert E.L., and Harper M.E. Uncoupling protein-3: clues in an ongoing mitochondrial mystery. FASEB J. 21 (2007) 312-324
-
(2007)
FASEB J.
, vol.21
, pp. 312-324
-
-
Bezaire, V.1
Seifert, E.L.2
Harper, M.E.3
-
30
-
-
35348972430
-
Genetic links between diet and lifespan: shared mechanisms from yeast to humans
-
Bishop N.A., and Guarente L. Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nat. Rev. Genet. 8 (2007) 835-844
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 835-844
-
-
Bishop, N.A.1
Guarente, L.2
-
31
-
-
33847378451
-
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis
-
Bjelakovic G., Nikolova D., Gluud L.L., Simonetti R.G., and Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. J. Am. Med. Assoc. 297 (2007) 842-857
-
(2007)
J. Am. Med. Assoc.
, vol.297
, pp. 842-857
-
-
Bjelakovic, G.1
Nikolova, D.2
Gluud, L.L.3
Simonetti, R.G.4
Gluud, C.5
-
32
-
-
38149107357
-
Paradoxes of aging
-
Blagosklonny M.V. Paradoxes of aging. Cell Cycle 6 (2007) 2997-3003
-
(2007)
Cell Cycle
, vol.6
, pp. 2997-3003
-
-
Blagosklonny, M.V.1
-
33
-
-
36849073113
-
Program-like aging and mitochondria: instead of random damage by free radicals
-
Blagosklonny M.V. Program-like aging and mitochondria: instead of random damage by free radicals. J. Cell. Biochem. 102 (2007) 1389-1399
-
(2007)
J. Cell. Biochem.
, vol.102
, pp. 1389-1399
-
-
Blagosklonny, M.V.1
-
34
-
-
37749014986
-
Kin selection and the evolutionary theory of aging
-
Bourke A.F.G. Kin selection and the evolutionary theory of aging. Annu. Rev. Ecol. Evol. Syst. 38 (2007) 103-128
-
(2007)
Annu. Rev. Ecol. Evol. Syst.
, vol.38
, pp. 103-128
-
-
Bourke, A.F.G.1
-
35
-
-
13844257506
-
The non-existent aging program: how does it work?
-
Bredesen D.E. The non-existent aging program: how does it work?. Aging Cell 3 (2004) 255-259
-
(2004)
Aging Cell
, vol.3
, pp. 255-259
-
-
Bredesen, D.E.1
-
36
-
-
0021202816
-
Effect of unsaturated acids on membrane structure and enzyme kinetics
-
Brenner R.R. Effect of unsaturated acids on membrane structure and enzyme kinetics. Prog. Lipid Res. 23 (1984) 69-96
-
(1984)
Prog. Lipid Res.
, vol.23
, pp. 69-96
-
-
Brenner, R.R.1
-
37
-
-
0032147165
-
The biological significance of plasmalogens in defense against oxidative damage
-
Brosche T., and Platt D. The biological significance of plasmalogens in defense against oxidative damage. Exp. Gerontol. 33 (1998) 363-369
-
(1998)
Exp. Gerontol.
, vol.33
, pp. 363-369
-
-
Brosche, T.1
Platt, D.2
-
39
-
-
0026663037
-
A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis
-
Brunk U.T., Jones C.B., and Sohal R.S. A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis. Mutat. Res. 275 (1992) 395-403
-
(1992)
Mutat. Res.
, vol.275
, pp. 395-403
-
-
Brunk, U.T.1
Jones, C.B.2
Sohal, R.S.3
-
40
-
-
42249088900
-
Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species
-
Buffenstein R. Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species. J. Comp. Physiol. B. 178 (2008) 439-445
-
(2008)
J. Comp. Physiol. B.
, vol.178
, pp. 439-445
-
-
Buffenstein, R.1
-
41
-
-
0035056792
-
Age determination and validation studies of marine fishes: do deep-dwellers live longer?
-
Cailliet G.M., Andrews A.H., Burton E.J., Watters D.L., Kline D.E., and Ferry-Graham L.A. Age determination and validation studies of marine fishes: do deep-dwellers live longer?. Exp. Gerontol. 36 (2001) 739-764
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 739-764
-
-
Cailliet, G.M.1
Andrews, A.H.2
Burton, E.J.3
Watters, D.L.4
Kline, D.E.5
Ferry-Graham, L.A.6
-
43
-
-
34250844410
-
Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
-
Calabrese E.J., Bachmann K.A., Bailer A.J., Bolger P.M., Borak J., Cai L., Cedergreen N., Cherian M.G., Chiueh C.C., Clarkson T.W., Cook R.R., Diamond D.M., Doolittle D.J., Dorato M.A., Duke S.O., Feinendegen L., Gardner D.E., Hart R.W., Hastings K.L., Hayes A.W., Hoffmann G.R., Ives J.A., Jaworowski Z., Johnson T.E., Jonas W.B., Kaminski N.E., Keller J.G., Klaunig J.E., Knudsen T.B., Kozumbo W.J., Lettieri T., Liu S.-Z., Maisseu A., Maynard K.I., Masoro E.J., McClellan R.O., Mehendale H.M., Mothersill C., Newlin D.B., Nigg H.N., Oehme F.W., Phalen R.F., Philbert M.A., Rattan S.I.S., Riviere J.E., Rodricks J., Sapolsky R.M., Scott B.R., Seymour C., Sinclair D.A., Smith-Sonneborn J., Snow E.T., Spear L., Stevenson D.E., Thomas Y., Tubiana M., Williams G.M., and Mattson M.P. Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol. Appl. Pharmacol. 222 (2007) 122-128
-
(2007)
Toxicol. Appl. Pharmacol.
, vol.222
, pp. 122-128
-
-
Calabrese, E.J.1
Bachmann, K.A.2
Bailer, A.J.3
Bolger, P.M.4
Borak, J.5
Cai, L.6
Cedergreen, N.7
Cherian, M.G.8
Chiueh, C.C.9
Clarkson, T.W.10
Cook, R.R.11
Diamond, D.M.12
Doolittle, D.J.13
Dorato, M.A.14
Duke, S.O.15
Feinendegen, L.16
Gardner, D.E.17
Hart, R.W.18
Hastings, K.L.19
Hayes, A.W.20
Hoffmann, G.R.21
Ives, J.A.22
Jaworowski, Z.23
Johnson, T.E.24
Jonas, W.B.25
Kaminski, N.E.26
Keller, J.G.27
Klaunig, J.E.28
Knudsen, T.B.29
Kozumbo, W.J.30
Lettieri, T.31
Liu, S.-Z.32
Maisseu, A.33
Maynard, K.I.34
Masoro, E.J.35
McClellan, R.O.36
Mehendale, H.M.37
Mothersill, C.38
Newlin, D.B.39
Nigg, H.N.40
Oehme, F.W.41
Phalen, R.F.42
Philbert, M.A.43
Rattan, S.I.S.44
Riviere, J.E.45
Rodricks, J.46
Sapolsky, R.M.47
Scott, B.R.48
Seymour, C.49
Sinclair, D.A.50
Smith-Sonneborn, J.51
Snow, E.T.52
Spear, L.53
Stevenson, D.E.54
Thomas, Y.55
Tubiana, M.56
Williams, G.M.57
Mattson, M.P.58
more..
-
44
-
-
33746830525
-
n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases
-
Calder P.C. n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am. J. Clin. Nutr. 83 (2006) 1505S-1519S
-
(2006)
Am. J. Clin. Nutr.
, vol.83
-
-
Calder, P.C.1
-
45
-
-
5344234445
-
4-Hydroxynonenal regulates 26S proteasomal degradation of alcohol dehydrogenase
-
Carbone D.L., Doorn J.A., and Petersen D.R. 4-Hydroxynonenal regulates 26S proteasomal degradation of alcohol dehydrogenase. Free Radic. Biol. Med. 37 (2004) 1430-1439
-
(2004)
Free Radic. Biol. Med.
, vol.37
, pp. 1430-1439
-
-
Carbone, D.L.1
Doorn, J.A.2
Petersen, D.R.3
-
46
-
-
0036625836
-
Cortisol and Pacific salmon: a new look at the role of stress hormones in olfaction and home-stream migration
-
Carruth L.L., Jones R.E., and Norris D.O. Cortisol and Pacific salmon: a new look at the role of stress hormones in olfaction and home-stream migration. Integr. Comp. Biol. 42 (2002) 574-581
-
(2002)
Integr. Comp. Biol.
, vol.42
, pp. 574-581
-
-
Carruth, L.L.1
Jones, R.E.2
Norris, D.O.3
-
47
-
-
0037035382
-
Division of labour influences the rate of ageing in weaver ant workers
-
Chapuisat M., and Keller L. Division of labour influences the rate of ageing in weaver ant workers. Proc. R. Soc. Lond. B 269 (2002) 909-913
-
(2002)
Proc. R. Soc. Lond. B
, vol.269
, pp. 909-913
-
-
Chapuisat, M.1
Keller, L.2
-
48
-
-
41449112452
-
Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor γ expression and adipogenesis in cultured 3T3-L1 cells
-
Christianson J.L., Nicoloro S., Straubhaar J., and Czech M.P. Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor γ expression and adipogenesis in cultured 3T3-L1 cells. J. Biol. Chem. 283 (2008) 2906-2916
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 2906-2916
-
-
Christianson, J.L.1
Nicoloro, S.2
Straubhaar, J.3
Czech, M.P.4
-
49
-
-
0035815414
-
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
-
Clancy D.J., Gems D., Harshman L.G., Oldham S., Stocker H., Hafen E., Leevers S.J., and Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292 (2001) 104-106
-
(2001)
Science
, vol.292
, pp. 104-106
-
-
Clancy, D.J.1
Gems, D.2
Harshman, L.G.3
Oldham, S.4
Stocker, H.5
Hafen, E.6
Leevers, S.J.7
Partridge, L.8
-
50
-
-
25144496903
-
Gene expression patterns associated with queen honey bee longevity
-
Corona M., Hughes K.A., Weaver D.B., and Robinson G.E. Gene expression patterns associated with queen honey bee longevity. Mech. Ageing Dev. 126 (2005) 1230-1238
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 1230-1238
-
-
Corona, M.1
Hughes, K.A.2
Weaver, D.B.3
Robinson, G.E.4
-
51
-
-
0036198149
-
Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity
-
Cypser J.R., and Johnson T.E. Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity. J. Gerontol. A: Biol. Sci. Med. Sci. 57 (2002) B109-B114
-
(2002)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.57
-
-
Cypser, J.R.1
Johnson, T.E.2
-
53
-
-
36549017642
-
Calorie restriction, post-reproductive life span, and programmed aging: a plea for rigor
-
de Grey A.D. Calorie restriction, post-reproductive life span, and programmed aging: a plea for rigor. Ann. NY Acad. Sci. 1119 (2007) 296-305
-
(2007)
Ann. NY Acad. Sci.
, vol.1119
, pp. 296-305
-
-
de Grey, A.D.1
-
54
-
-
0038779369
-
Differential oxidative damage and expression of stress defence regulons in culturable and non-culturable Escherichia coli cells
-
Desnues B., Cuny C., Gregori G., Dukan S., Aguilaniu H., and Nystrom T. Differential oxidative damage and expression of stress defence regulons in culturable and non-culturable Escherichia coli cells. EMBO Rep. 4 (2003) 400-404
-
(2003)
EMBO Rep.
, vol.4
, pp. 400-404
-
-
Desnues, B.1
Cuny, C.2
Gregori, G.3
Dukan, S.4
Aguilaniu, H.5
Nystrom, T.6
-
55
-
-
33846849632
-
Role of 4-hydroxynonenal and its metabolites in signaling
-
Dwivedi S., Sharma A., Patrick B., Sharma R., and Awasthi Y.C. Role of 4-hydroxynonenal and its metabolites in signaling. Redox Rep. 12 (2007) 4-10
-
(2007)
Redox Rep.
, vol.12
, pp. 4-10
-
-
Dwivedi, S.1
Sharma, A.2
Patrick, B.3
Sharma, R.4
Awasthi, Y.C.5
-
56
-
-
33846787169
-
4-Hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production
-
Echtay K.S., and Brand M.D. 4-Hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production. Redox Rep. 12 (2007) 26-29
-
(2007)
Redox Rep.
, vol.12
, pp. 26-29
-
-
Echtay, K.S.1
Brand, M.D.2
-
57
-
-
0041465009
-
A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling
-
Echtay K.S., Esteves T.C., Pakay J.L., Jekabsons M.B., Lambert A.J., Portero-Otin M., Pamplona R., Vidal-Puig A.J., Wang S., Roebuck S.J., and Brand M.D. A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. EMBO J. 22 (2003) 4103-4110
-
(2003)
EMBO J.
, vol.22
, pp. 4103-4110
-
-
Echtay, K.S.1
Esteves, T.C.2
Pakay, J.L.3
Jekabsons, M.B.4
Lambert, A.J.5
Portero-Otin, M.6
Pamplona, R.7
Vidal-Puig, A.J.8
Wang, S.9
Roebuck, S.J.10
Brand, M.D.11
-
58
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
Esterbauer H., Schaur R.J., and Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11 (1991) 81-128
-
(1991)
Free Radic. Biol. Med.
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
59
-
-
33747770049
-
Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes
-
Farout L., Mary J., Vinh J., Szweda L.I., and Friguet B. Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes. Arch. Biochem. Biophys. 453 (2006) 135-142
-
(2006)
Arch. Biochem. Biophys.
, vol.453
, pp. 135-142
-
-
Farout, L.1
Mary, J.2
Vinh, J.3
Szweda, L.I.4
Friguet, B.5
-
61
-
-
0023831256
-
A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
-
Friedman D.B., and Johnson T.E. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 118 (1988) 75-86
-
(1988)
Genetics
, vol.118
, pp. 75-86
-
-
Friedman, D.B.1
Johnson, T.E.2
-
62
-
-
33646578189
-
Oxidized protein degradation and repair in ageing and oxidative stress
-
Friguet B. Oxidized protein degradation and repair in ageing and oxidative stress. FEBS Lett. 580 (2006) 2910-2916
-
(2006)
FEBS Lett.
, vol.580
, pp. 2910-2916
-
-
Friguet, B.1
-
63
-
-
0030977793
-
Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein
-
Friguet B., and Szweda L.I. Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein. FEBS Lett. 405 (1997) 21-25
-
(1997)
FEBS Lett.
, vol.405
, pp. 21-25
-
-
Friguet, B.1
Szweda, L.I.2
-
64
-
-
33750110432
-
Fatty acids as modulators of the immune response
-
Fritsche K. Fatty acids as modulators of the immune response. Annu. Rev. Nutr. 26 (2006) 45-73
-
(2006)
Annu. Rev. Nutr.
, vol.26
, pp. 45-73
-
-
Fritsche, K.1
-
65
-
-
0035976575
-
Prostaglandins and leukotrienes: advances in eicosanoid biology
-
Funk C.D. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 294 (2001) 1871-1875
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
66
-
-
12344309431
-
Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?
-
Gems D., and McElwee J.J. Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?. Mech. Ageing Dev. 126 (2005) 381-387
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 381-387
-
-
Gems, D.1
McElwee, J.J.2
-
67
-
-
39649110574
-
Stress-response hormesis and aging: "That which does not kill us makes us stronger"
-
Gems D., and Partridge L. Stress-response hormesis and aging: "That which does not kill us makes us stronger". Cell Metabol. 7 (2008) 200-203
-
(2008)
Cell Metabol.
, vol.7
, pp. 200-203
-
-
Gems, D.1
Partridge, L.2
-
68
-
-
23844436700
-
In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans
-
Gerstbrein B., Stamatas G., Kollias N., and Driscoll M. In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans. Aging Cell 4 (2005) 127-137
-
(2005)
Aging Cell
, vol.4
, pp. 127-137
-
-
Gerstbrein, B.1
Stamatas, G.2
Kollias, N.3
Driscoll, M.4
-
69
-
-
34250882745
-
Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex
-
Ghazi A., Henis-Korenblit S., and Kenyon C. Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 5947-5952
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 5947-5952
-
-
Ghazi, A.1
Henis-Korenblit, S.2
Kenyon, C.3
-
70
-
-
1342332179
-
Aging as an evolved characteristic-Weismann's theory reconsidered
-
Goldsmith T.C. Aging as an evolved characteristic-Weismann's theory reconsidered. Med. Hypotheses 62 (2004) 304-308
-
(2004)
Med. Hypotheses
, vol.62
, pp. 304-308
-
-
Goldsmith, T.C.1
-
71
-
-
53049096482
-
-
Goldsmith, T.C., in press. Aging, evolvability, and the individual benefit requirement: medical implications of aging theory controversies. J. Theor. Biol.
-
Goldsmith, T.C., in press. Aging, evolvability, and the individual benefit requirement: medical implications of aging theory controversies. J. Theor. Biol.
-
-
-
-
72
-
-
43749099217
-
Deleterious role of superoxide dismutase in the mitochondrial intermembrane space
-
Goldsteins G., Keksa-Goldsteine V., Ahtoniemi T., Jaronen M., Arens E., Akerman K., Chan P.H., and Koistinaho J. Deleterious role of superoxide dismutase in the mitochondrial intermembrane space. J. Biol. Chem. 283 (2008) 8446-8452
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8446-8452
-
-
Goldsteins, G.1
Keksa-Goldsteine, V.2
Ahtoniemi, T.3
Jaronen, M.4
Arens, E.5
Akerman, K.6
Chan, P.H.7
Koistinaho, J.8
-
73
-
-
0003293418
-
On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies
-
Gompertz B. On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies. Philos. Trans. R. Soc. Lond. 115 (1825) 513-585
-
(1825)
Philos. Trans. R. Soc. Lond.
, vol.115
, pp. 513-585
-
-
Gompertz, B.1
-
75
-
-
40949149823
-
Signaling networks in aging
-
Greer E.L., and Brunet A. Signaling networks in aging. J. Cell Sci. 121 (2008) 407-412
-
(2008)
J. Cell Sci.
, vol.121
, pp. 407-412
-
-
Greer, E.L.1
Brunet, A.2
-
77
-
-
0003562737
-
-
W.H. Freeman, New York
-
Griffiths A.J.F., Miller J.H., Suzuki D.T., Lewontin R.C., and Gelbart W.M. An Introduction to Genetic Analysis. 6th ed. (1996), W.H. Freeman, New York
-
(1996)
An Introduction to Genetic Analysis. 6th ed.
-
-
Griffiths, A.J.F.1
Miller, J.H.2
Suzuki, D.T.3
Lewontin, R.C.4
Gelbart, W.M.5
-
78
-
-
0041669528
-
The proteasomal system and HNE-modified proteins
-
Grune T., and Davies K.J.A. The proteasomal system and HNE-modified proteins. Mol. Aspects Med. 24 (2003) 195-204
-
(2003)
Mol. Aspects Med.
, vol.24
, pp. 195-204
-
-
Grune, T.1
Davies, K.J.A.2
-
79
-
-
38649132337
-
Mitochondria-a nexus for aging, calorie restriction, and sirtuins?
-
Guarente L. Mitochondria-a nexus for aging, calorie restriction, and sirtuins?. Cell 132 (2008) 171-176
-
(2008)
Cell
, vol.132
, pp. 171-176
-
-
Guarente, L.1
-
81
-
-
0025369970
-
The measurement and mechanism of lipid peroxidation in biological systems
-
Gutteridge J.M.C., and Halliwell B. The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem. Sci. (TIBS) 15 (1990) 129-135
-
(1990)
Trends Biochem. Sci. (TIBS)
, vol.15
, pp. 129-135
-
-
Gutteridge, J.M.C.1
Halliwell, B.2
-
82
-
-
34248595963
-
Extended longevity of queen honey bees compared to workers is associated with peroxidation-resistant membranes
-
Haddad L.S., Kelbert L., and Hulbert A.J. Extended longevity of queen honey bees compared to workers is associated with peroxidation-resistant membranes. Exp. Gerontol. 42 (2007) 601-609
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 601-609
-
-
Haddad, L.S.1
Kelbert, L.2
Hulbert, A.J.3
-
83
-
-
36348972777
-
Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse
-
Hakimi P., Yang J., Casadesus G., Massillon D., Tolentino-Silva F., Nye C.K., Cabrera M.E., Hagen D.R., Utter C.B., Baghdy Y., Johnson D.H., Wilson D.L., Kirwan J.P., Kalhan S.C., and Hanson R.W. Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse. J. Biol. Chem. 282 (2007) 32844-32855
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32844-32855
-
-
Hakimi, P.1
Yang, J.2
Casadesus, G.3
Massillon, D.4
Tolentino-Silva, F.5
Nye, C.K.6
Cabrera, M.E.7
Hagen, D.R.8
Utter, C.B.9
Baghdy, Y.10
Johnson, D.H.11
Wilson, D.L.12
Kirwan, J.P.13
Kalhan, S.C.14
Hanson, R.W.15
-
84
-
-
0013942563
-
The moulding of senescence by natural selection
-
Hamilton W.D. The moulding of senescence by natural selection. J. Theor. Biol. 12 (1966) 12-45
-
(1966)
J. Theor. Biol.
, vol.12
, pp. 12-45
-
-
Hamilton, W.D.1
-
85
-
-
40149105890
-
A role for autophagy genes in the extension of lifespan by dietary restriction in C. elegans
-
Hansen M., Chandra A., Mitic L.L., Onken B., Driscoll M., and Kenyon C. A role for autophagy genes in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet. 4 (2008) e24
-
(2008)
PLoS Genet.
, vol.4
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
Onken, B.4
Driscoll, M.5
Kenyon, C.6
-
86
-
-
53049107946
-
-
Hanson, R.W., Hakimi, P., in press. Born to run; the story of the PEPCK-C(mus) mouse. Biochimie.
-
Hanson, R.W., Hakimi, P., in press. Born to run; the story of the PEPCK-C(mus) mouse. Biochimie.
-
-
-
-
87
-
-
77049308856
-
Aging: a theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11 (1956) 298-300
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
88
-
-
38149037201
-
The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomes
-
Hashimoto K., Yoshizawa A.C., Okuda S., Kuma K., Goto S., and Kanehisa M. The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomes. J. Lipid Res. 49 (2008) 183-191
-
(2008)
J. Lipid Res.
, vol.49
, pp. 183-191
-
-
Hashimoto, K.1
Yoshizawa, A.C.2
Okuda, S.3
Kuma, K.4
Goto, S.5
Kanehisa, M.6
-
90
-
-
37749036806
-
Entropy explains aging, genetic determinism explains longevity, and undefined terminology explains misunderstanding both
-
Hayflick L. Entropy explains aging, genetic determinism explains longevity, and undefined terminology explains misunderstanding both. PLoS Genet. 3 (2007) e220
-
(2007)
PLoS Genet.
, vol.3
-
-
Hayflick, L.1
-
91
-
-
53049091198
-
-
Heinze, J., Schrempf, A., in press. Aging and reproduction in social insects. Gerontology.
-
Heinze, J., Schrempf, A., in press. Aging and reproduction in social insects. Gerontology.
-
-
-
-
92
-
-
0038826959
-
Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress
-
Hercus M.J., Loeschcke V., and Rattan S.I. Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress. Biogerontology 4 (2003) 149-156
-
(2003)
Biogerontology
, vol.4
, pp. 149-156
-
-
Hercus, M.J.1
Loeschcke, V.2
Rattan, S.I.3
-
93
-
-
33646744719
-
Elimination of damaged proteins during differentiation of embryonic stem cells
-
Hernebring M., Brolen G., Aguilaniu H., Semb H., and Nystrom T. Elimination of damaged proteins during differentiation of embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 7700-7705
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 7700-7705
-
-
Hernebring, M.1
Brolen, G.2
Aguilaniu, H.3
Semb, H.4
Nystrom, T.5
-
95
-
-
33847083503
-
Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the short-chain dehydrogenase/reductase superfamily
-
Hoffmann F., and Maser E. Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the short-chain dehydrogenase/reductase superfamily. Drug Metabol. Rev. 39 (2007) 87-144
-
(2007)
Drug Metabol. Rev.
, vol.39
, pp. 87-144
-
-
Hoffmann, F.1
Maser, E.2
-
96
-
-
0028139773
-
Fly now, die later: life-history correlates of gliding and flying in mammals
-
Holmes D.J., and Austad S.N. Fly now, die later: life-history correlates of gliding and flying in mammals. J. Mammal. 75 (1994) 224-226
-
(1994)
J. Mammal.
, vol.75
, pp. 224-226
-
-
Holmes, D.J.1
Austad, S.N.2
-
97
-
-
53049104246
-
-
Honda, Y., Tanaka, M., Honda, S., in press. Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans. Exp. Gerontol.
-
Honda, Y., Tanaka, M., Honda, S., in press. Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans. Exp. Gerontol.
-
-
-
-
98
-
-
33744494572
-
The free radical fantasy: a panoply of paradoxes
-
Howes R.M. The free radical fantasy: a panoply of paradoxes. Ann. NY Acad. Sci. 1067 (2006) 22-26
-
(2006)
Ann. NY Acad. Sci.
, vol.1067
, pp. 22-26
-
-
Howes, R.M.1
-
99
-
-
0033563005
-
Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of π class human glutathione S-transferases
-
Hu X., Herzog C., Zimniak P., and Singh S.V. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of π class human glutathione S-transferases. Cancer Res. 59 (1999) 2358-2362
-
(1999)
Cancer Res.
, vol.59
, pp. 2358-2362
-
-
Hu, X.1
Herzog, C.2
Zimniak, P.3
Singh, S.V.4
-
100
-
-
0031577576
-
Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons
-
Hu X., Xia H., Srivastava S.K., Herzog C., Awasthi Y.C., Ji X., Zimniak P., and Singh S.V. Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons. Biochem. Biophys. Res. Commun. 238 (1997) 397-402
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.238
, pp. 397-402
-
-
Hu, X.1
Xia, H.2
Srivastava, S.K.3
Herzog, C.4
Awasthi, Y.C.5
Ji, X.6
Zimniak, P.7
Singh, S.V.8
-
101
-
-
0034006162
-
Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice
-
Huang T.T., Carlson E.J., Gillespie A.M., Shi Y., and Epstein C.J. Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice. J. Gerontol. A: Biol. Sci. Med. Sci. 55 (2000) B5-B9
-
(2000)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.55
-
-
Huang, T.T.1
Carlson, E.J.2
Gillespie, A.M.3
Shi, Y.4
Epstein, C.J.5
-
102
-
-
14744296990
-
On the importance of fatty acid composition of membranes for aging
-
Hulbert A.J. On the importance of fatty acid composition of membranes for aging. J. Theor. Biol. 234 (2005) 277-288
-
(2005)
J. Theor. Biol.
, vol.234
, pp. 277-288
-
-
Hulbert, A.J.1
-
103
-
-
6944246521
-
Food consumption and individual lifespan of adults of the blowfly Calliphora stygia: a test of the 'rate of living' theory of aging
-
Hulbert A.J., Usher M.J., and Wallman J.F. Food consumption and individual lifespan of adults of the blowfly Calliphora stygia: a test of the 'rate of living' theory of aging. Exp. Gerontol. 39 (2004) 1485-1490
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 1485-1490
-
-
Hulbert, A.J.1
Usher, M.J.2
Wallman, J.F.3
-
104
-
-
34248541922
-
Life and death: metabolic rate, membrane composition, and life span of animals
-
Hulbert A.J., Pamplona R., Buffenstein R., and Buttemer W.A. Life and death: metabolic rate, membrane composition, and life span of animals. Physiol. Rev. 87 (2007) 1175-1213
-
(2007)
Physiol. Rev.
, vol.87
, pp. 1175-1213
-
-
Hulbert, A.J.1
Pamplona, R.2
Buffenstein, R.3
Buttemer, W.A.4
-
105
-
-
33745216273
-
Extended longevity of wild-derived mice is associated with peroxidation-resistant membranes
-
Hulbert A.J., Faulks S.C., Harper J.M., Miller R.A., and Buffenstein R. Extended longevity of wild-derived mice is associated with peroxidation-resistant membranes. Mech. Ageing Dev. 127 (2006) 653-657
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 653-657
-
-
Hulbert, A.J.1
Faulks, S.C.2
Harper, J.M.3
Miller, R.A.4
Buffenstein, R.5
-
106
-
-
0034640337
-
Detection of lipofuscin-like fluorophore in oxidized human low-density lipoprotein 4-hydroxy-2-nonenal as a potential source of fluorescent chromophore
-
Itakura K., Oya-Ito T., Osawa T., Yamada S., Toyokuni S., Shibata N., Kobayashi M., and Uchida K. Detection of lipofuscin-like fluorophore in oxidized human low-density lipoprotein 4-hydroxy-2-nonenal as a potential source of fluorescent chromophore. FEBS Lett. 473 (2000) 249-253
-
(2000)
FEBS Lett.
, vol.473
, pp. 249-253
-
-
Itakura, K.1
Oya-Ito, T.2
Osawa, T.3
Yamada, S.4
Toyokuni, S.5
Shibata, N.6
Kobayashi, M.7
Uchida, K.8
-
107
-
-
0036406950
-
Growing old: metabolic control and yeast aging
-
Jazwinski S.M. Growing old: metabolic control and yeast aging. Annu. Rev. Microbiol. 56 (2002) 769-792
-
(2002)
Annu. Rev. Microbiol.
, vol.56
, pp. 769-792
-
-
Jazwinski, S.M.1
-
108
-
-
30344448851
-
Phase I" and "phase II" drug metabolism: terminology that we should phase out?
-
Josephy P.D., Guengerich F.P., and Miners J.O. Phase I" and "phase II" drug metabolism: terminology that we should phase out?. Drug Metabol. Rev. 37 (2005) 575-580
-
(2005)
Drug Metabol. Rev.
, vol.37
, pp. 575-580
-
-
Josephy, P.D.1
Guengerich, F.P.2
Miners, J.O.3
-
109
-
-
2942555103
-
Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans
-
Keaney M., Matthijssens F., Sharpe M., Vanfleteren J., and Gems D. Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans. Free Radic. Biol. Med. 37 (2004) 239-250
-
(2004)
Free Radic. Biol. Med.
, vol.37
, pp. 239-250
-
-
Keaney, M.1
Matthijssens, F.2
Sharpe, M.3
Vanfleteren, J.4
Gems, D.5
-
110
-
-
13944269223
-
The plasticity of aging: insights from long-lived mutants
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell 120 (2005) 449-460
-
(2005)
Cell
, vol.120
, pp. 449-460
-
-
Kenyon, C.1
-
111
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C., Chang J., Gensch E., Rudner A., and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 366 (1993) 461-464
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
112
-
-
26844522359
-
Possibility of selection against mtDNA mutations in tumors
-
Khaidakov M., and Shmookler Reis R.J. Possibility of selection against mtDNA mutations in tumors. Mol. Cancer 4 (2005) 36
-
(2005)
Mol. Cancer
, vol.4
, pp. 36
-
-
Khaidakov, M.1
Shmookler Reis, R.J.2
-
113
-
-
43449117754
-
Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans
-
Kim J., Takahashi M., Shimizu T., Shirasawa T., Kajita M., Kanayama A., and Miyamoto Y. Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans. Mech. Ageing Dev. 129 (2008) 322-331
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 322-331
-
-
Kim, J.1
Takahashi, M.2
Shimizu, T.3
Shirasawa, T.4
Kajita, M.5
Kanayama, A.6
Miyamoto, Y.7
-
114
-
-
13944262937
-
Understanding the odd science of aging
-
Kirkwood T.B. Understanding the odd science of aging. Cell 120 (2005) 437-447
-
(2005)
Cell
, vol.120
, pp. 437-447
-
-
Kirkwood, T.B.1
-
115
-
-
38949145803
-
A systematic look at an old problem
-
Kirkwood T.B. A systematic look at an old problem. Nature 451 (2008) 644-647
-
(2008)
Nature
, vol.451
, pp. 644-647
-
-
Kirkwood, T.B.1
-
116
-
-
38349151564
-
Understanding ageing from an evolutionary perspective
-
Kirkwood T.B. Understanding ageing from an evolutionary perspective. J. Int. Med. 263 (2008) 117-127
-
(2008)
J. Int. Med.
, vol.263
, pp. 117-127
-
-
Kirkwood, T.B.1
-
117
-
-
12344326033
-
What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment?
-
Kirkwood T.B., Feder M., Finch C.E., Franceschi C., Globerson A., Klingenberg C.P., Lamarco K., Omholt S., and Westendorp R.G. What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment?. Mech. Ageing Dev. 126 (2005) 439-443
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 439-443
-
-
Kirkwood, T.B.1
Feder, M.2
Finch, C.E.3
Franceschi, C.4
Globerson, A.5
Klingenberg, C.P.6
Lamarco, K.7
Omholt, S.8
Westendorp, R.G.9
-
118
-
-
0017782437
-
Evolution of ageing
-
Kirkwood T.B.L. Evolution of ageing. Nature 270 (1977) 301-304
-
(1977)
Nature
, vol.270
, pp. 301-304
-
-
Kirkwood, T.B.L.1
-
119
-
-
0037167844
-
Ageing-the old worm turns more slowly
-
Kirkwood T.B.L., and Finch C.E. Ageing-the old worm turns more slowly. Nature 419 (2002) 794-795
-
(2002)
Nature
, vol.419
, pp. 794-795
-
-
Kirkwood, T.B.L.1
Finch, C.E.2
-
120
-
-
33847620225
-
Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases
-
Krause K.H. Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases. Exp. Gerontol. 42 (2006) 256-262
-
(2006)
Exp. Gerontol.
, vol.42
, pp. 256-262
-
-
Krause, K.H.1
-
121
-
-
33745088341
-
Evidence that plasmalogen is protective against oxidative stress in the rat brain
-
Kuczynski B., and Reo N. Evidence that plasmalogen is protective against oxidative stress in the rat brain. Neurochem. Res. 31 (2006) 639-656
-
(2006)
Neurochem. Res.
, vol.31
, pp. 639-656
-
-
Kuczynski, B.1
Reo, N.2
-
122
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth G.C., Hiona A., Pugh T.D., Someya S., Panzer K., Wohlgemuth S.E., Hofer T., Seo A.Y., Sullivan R., Jobling W.A., Morrow J.D., Van Remmen H., Sedivy J.M., Yamasoba T., Tanokura M., Weindruch R., Leeuwenburgh C., and Prolla T.A. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309 (2005) 481-484
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
Morrow, J.D.11
Van Remmen, H.12
Sedivy, J.M.13
Yamasoba, T.14
Tanokura, M.15
Weindruch, R.16
Leeuwenburgh, C.17
Prolla, T.A.18
-
123
-
-
0027104840
-
Translational accuracy and the fitness of bacteria
-
Kurland C.G. Translational accuracy and the fitness of bacteria. Annu. Rev. Genet. 26 (1992) 29-50
-
(1992)
Annu. Rev. Genet.
, vol.26
, pp. 29-50
-
-
Kurland, C.G.1
-
124
-
-
34249815482
-
Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron
-
Kurz T., Terman A., and Brunk U.T. Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron. Arch. Biochem. Biophys. 462 (2007) 220-230
-
(2007)
Arch. Biochem. Biophys.
, vol.462
, pp. 220-230
-
-
Kurz, T.1
Terman, A.2
Brunk, U.T.3
-
126
-
-
0031279003
-
Implications of trends in marine-derived nutrient influx to south coastal British Columbia salmonid production
-
Larkin G.A., and Slaney P.A. Implications of trends in marine-derived nutrient influx to south coastal British Columbia salmonid production. Fisheries 22 (1997) 16-24
-
(1997)
Fisheries
, vol.22
, pp. 16-24
-
-
Larkin, G.A.1
Slaney, P.A.2
-
127
-
-
33748809208
-
4-Hydroxynonenal induces vascular smooth muscle cell apoptosis through mitochondrial generation of reactive oxygen species
-
Lee J.Y., Jung G.Y., Heo H.J., Yun M.R., Park J.Y., Bae S.S., Hong K.W., Lee W.S., and Kim C.D. 4-Hydroxynonenal induces vascular smooth muscle cell apoptosis through mitochondrial generation of reactive oxygen species. Toxicol. Lett. 166 (2006) 212-221
-
(2006)
Toxicol. Lett.
, vol.166
, pp. 212-221
-
-
Lee, J.Y.1
Jung, G.Y.2
Heo, H.J.3
Yun, M.R.4
Park, J.Y.5
Bae, S.S.6
Hong, K.W.7
Lee, W.S.8
Kim, C.D.9
-
129
-
-
0004279283
-
-
Oxford University Press, Oxford
-
Lewin B. Genes VI (1997), Oxford University Press, Oxford
-
(1997)
Genes VI
-
-
Lewin, B.1
-
130
-
-
33751436084
-
Why aging isn't regulated: a lamentation on the use of language in aging literature
-
Lithgow G.J. Why aging isn't regulated: a lamentation on the use of language in aging literature. Exp. Gerontol. 41 (2006) 890-893
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 890-893
-
-
Lithgow, G.J.1
-
131
-
-
0029123058
-
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
-
Lithgow G.J., White T.M., Melov S., and Johnson T.E. Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 7540-7544
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 7540-7544
-
-
Lithgow, G.J.1
White, T.M.2
Melov, S.3
Johnson, T.E.4
-
132
-
-
40849126309
-
Promotion of amyloid beta protein misfolding and fibrillogenesis by a lipid oxidation product
-
Liu L., Komatsu H., Murray I.V., and Axelsen P.H. Promotion of amyloid beta protein misfolding and fibrillogenesis by a lipid oxidation product. J. Mol. Biol. 377 (2008) 1236-1250
-
(2008)
J. Mol. Biol.
, vol.377
, pp. 1236-1250
-
-
Liu, L.1
Komatsu, H.2
Murray, I.V.3
Axelsen, P.H.4
-
133
-
-
0013222143
-
Mass spectroscopic characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal
-
Liu Z., Minkler P.E., and Sayre L.M. Mass spectroscopic characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal. Chem. Res. Toxicol. 16 (2003) 901-911
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 901-911
-
-
Liu, Z.1
Minkler, P.E.2
Sayre, L.M.3
-
134
-
-
28844485678
-
Effects of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans
-
Lombardo Y.B., and Chicco A.G. Effects of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans. J. Nutr. Biochem. 17 (2006) 1-13
-
(2006)
J. Nutr. Biochem.
, vol.17
, pp. 1-13
-
-
Lombardo, Y.B.1
Chicco, A.G.2
-
135
-
-
42449100496
-
Trans-4-hydroxy-2-hexenal is a neurotoxic product of docosahexaenoic (22:6; n-3) acid oxidation
-
Long E.K., Murphy T.C., Leiphon L.J., Watt J., Morrow J.D., Milne G.L., Howard J.R., and Picklo Sr. M.J. Trans-4-hydroxy-2-hexenal is a neurotoxic product of docosahexaenoic (22:6; n-3) acid oxidation. J. Neurochem. 105 (2008) 714-724
-
(2008)
J. Neurochem.
, vol.105
, pp. 714-724
-
-
Long, E.K.1
Murphy, T.C.2
Leiphon, L.J.3
Watt, J.4
Morrow, J.D.5
Milne, G.L.6
Howard, J.R.7
Picklo Sr., M.J.8
-
138
-
-
7044224838
-
Membrane fluidity and its roles in the perception of environmental signals
-
Los D.A., and Murata N. Membrane fluidity and its roles in the perception of environmental signals. Biochim. Biophys. Acta 1666 (2004) 142-157
-
(2004)
Biochim. Biophys. Acta
, vol.1666
, pp. 142-157
-
-
Los, D.A.1
Murata, N.2
-
139
-
-
41749107942
-
Stochasticity and cell fate
-
Losick R., and Desplan C. Stochasticity and cell fate. Science 320 (2008) 65-68
-
(2008)
Science
, vol.320
, pp. 65-68
-
-
Losick, R.1
Desplan, C.2
-
140
-
-
0037911448
-
Experimental researches on the role of phosphoinositide-specific phospholipase C in 4-hydroxynonenal induced exocytosis
-
Maggiora M., and Rossi M.A. Experimental researches on the role of phosphoinositide-specific phospholipase C in 4-hydroxynonenal induced exocytosis. Cell Biochem. Funct. 21 (2003) 155-160
-
(2003)
Cell Biochem. Funct.
, vol.21
, pp. 155-160
-
-
Maggiora, M.1
Rossi, M.A.2
-
141
-
-
33344479169
-
The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster
-
Magwere T., West M., Riyahi K., Murphy M.P., Smith R.A., and Partridge L. The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster. Mech. Ageing Dev. 127 (2006) 356-370
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 356-370
-
-
Magwere, T.1
West, M.2
Riyahi, K.3
Murphy, M.P.4
Smith, R.A.5
Partridge, L.6
-
142
-
-
33747591249
-
Dynamics in the plasma membrane: how to combine fluidity and order
-
Marguet D., Lenne P.F., Rigneault H., and He H.T. Dynamics in the plasma membrane: how to combine fluidity and order. EMBO J. 25 (2006) 3446-3457
-
(2006)
EMBO J.
, vol.25
, pp. 3446-3457
-
-
Marguet, D.1
Lenne, P.F.2
Rigneault, H.3
He, H.T.4
-
143
-
-
0037373455
-
Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein
-
Marnett L.J., Riggins J.N., and West J.D. Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein. J. Clin. Invest. 111 (2003) 583-593
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 583-593
-
-
Marnett, L.J.1
Riggins, J.N.2
West, J.D.3
-
144
-
-
0030028185
-
Somatic mutations are frequent and increase with age in human kidney epithelial cells
-
Martin G.M., Ogburn C.E., Colgin L.M., Gown A.M., Edland S.D., and Monnat Jr. R.J. Somatic mutations are frequent and increase with age in human kidney epithelial cells. Hum. Mol. Genet. 5 (1996) 215-221
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 215-221
-
-
Martin, G.M.1
Ogburn, C.E.2
Colgin, L.M.3
Gown, A.M.4
Edland, S.D.5
Monnat Jr., R.J.6
-
145
-
-
0033083733
-
It's a noisy business! Genetic regulation at the nanomolar scale
-
McAdams H.H., and Arkin A. It's a noisy business! Genetic regulation at the nanomolar scale. Trends Genet. 15 (1999) 65-69
-
(1999)
Trends Genet.
, vol.15
, pp. 65-69
-
-
McAdams, H.H.1
Arkin, A.2
-
146
-
-
36448969497
-
Evolutionary conservation of regulated longevity assurance mechanisms
-
McElwee J., Schuster E., Blanc E., Piper M., Thomas J., Patel D., Selman C., Withers D., Thornton J., Partridge L., and Gems D. Evolutionary conservation of regulated longevity assurance mechanisms. Genome Biol. 8 (2007) R132
-
(2007)
Genome Biol.
, vol.8
-
-
McElwee, J.1
Schuster, E.2
Blanc, E.3
Piper, M.4
Thomas, J.5
Patel, D.6
Selman, C.7
Withers, D.8
Thornton, J.9
Partridge, L.10
Gems, D.11
-
147
-
-
7244238167
-
Shared transcriptional signature in Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
-
McElwee J.J., Schuster E., Blanc E., Thomas J.H., and Gems D. Shared transcriptional signature in Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. J. Biol. Chem. 279 (2004) 44533-44543
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44533-44543
-
-
McElwee, J.J.1
Schuster, E.2
Blanc, E.3
Thomas, J.H.4
Gems, D.5
-
149
-
-
13844286010
-
Introduction-head-to-head debate: is there a program for aging?
-
Melov S. Introduction-head-to-head debate: is there a program for aging?. Aging Cell 3 (2004) 247-1247
-
(2004)
Aging Cell
, vol.3
, pp. 247-1247
-
-
Melov, S.1
-
150
-
-
0034284973
-
Extension of life-span with superoxide dismutase/catalase mimetics
-
Melov S., Ravenscroft J., Malik S., Gill M.S., Walker D.W., Clayton P.E., Wallace D.C., Malfroy B., Doctrow S.R., and Lithgow G.J. Extension of life-span with superoxide dismutase/catalase mimetics. Science 289 (2000) 1567-1569
-
(2000)
Science
, vol.289
, pp. 1567-1569
-
-
Melov, S.1
Ravenscroft, J.2
Malik, S.3
Gill, M.S.4
Walker, D.W.5
Clayton, P.E.6
Wallace, D.C.7
Malfroy, B.8
Doctrow, S.R.9
Lithgow, G.J.10
-
151
-
-
37249035554
-
Genetic removal of tri-unsaturated fatty acids suppresses developmental and molecular phenotypes of an arabidopsis tocopherol deficient mutant: whole-body mapping of malondialdehyde pools in a complex eukaryote
-
Mene-Saffrane L., Davoine C., Stolz S., Majcherczyk P., and Farmer E.E. Genetic removal of tri-unsaturated fatty acids suppresses developmental and molecular phenotypes of an arabidopsis tocopherol deficient mutant: whole-body mapping of malondialdehyde pools in a complex eukaryote. J. Biol. Chem. 282 (2007) 35749-35756
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35749-35756
-
-
Mene-Saffrane, L.1
Davoine, C.2
Stolz, S.3
Majcherczyk, P.4
Farmer, E.E.5
-
152
-
-
33746000739
-
Salmon, wildlife, and wine: marine-derived nutrients in human-dominated ecosystems of central California
-
Merz J.E., and Moyle P.B. Salmon, wildlife, and wine: marine-derived nutrients in human-dominated ecosystems of central California. Ecol. Appl. 16 (2006) 999-1009
-
(2006)
Ecol. Appl.
, vol.16
, pp. 999-1009
-
-
Merz, J.E.1
Moyle, P.B.2
-
153
-
-
53049104399
-
Entropy, order and disorder
-
Michaelides E.E. Entropy, order and disorder. Open Thermodyn. J. 2 (2008) 7-11
-
(2008)
Open Thermodyn. J.
, vol.2
, pp. 7-11
-
-
Michaelides, E.E.1
-
154
-
-
0141673128
-
Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms
-
Mikkelsen R.B., and Wardman P. Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms. Oncogene 22 (2003) 5734-5754
-
(2003)
Oncogene
, vol.22
, pp. 5734-5754
-
-
Mikkelsen, R.B.1
Wardman, P.2
-
155
-
-
0035061235
-
Escaping senescence: demographic data from the three-toed box turtle (Terrapene carolina triunguis)
-
Miller J.K. Escaping senescence: demographic data from the three-toed box turtle (Terrapene carolina triunguis). Exp. Gerontol. 36 (2001) 829-832
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 829-832
-
-
Miller, J.K.1
-
156
-
-
0036656427
-
Longer life spans and delayed maturation in wild-derived mice
-
Miller R.A., Harper J.M., Dysko R.C., Durkee S.J., and Austad S.N. Longer life spans and delayed maturation in wild-derived mice. Exp. Biol. Med. 227 (2002) 500-508
-
(2002)
Exp. Biol. Med.
, vol.227
, pp. 500-508
-
-
Miller, R.A.1
Harper, J.M.2
Dysko, R.C.3
Durkee, S.J.4
Austad, S.N.5
-
157
-
-
35448999303
-
Membrane phospholipid composition may contribute to exceptional longevity of the naked mole-rat (Heterocephalus glaber): a comparative study using shotgun lipidomics
-
Mitchell T.W., Buffenstein R., and Hulbert A.J. Membrane phospholipid composition may contribute to exceptional longevity of the naked mole-rat (Heterocephalus glaber): a comparative study using shotgun lipidomics. Exp. Gerontol. 42 (2007) 1053-1062
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 1053-1062
-
-
Mitchell, T.W.1
Buffenstein, R.2
Hulbert, A.J.3
-
158
-
-
0036671827
-
Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span
-
Mitsui A., Hamuro J., Nakamura H., Kondo N., Hirabayashi Y., Ishizaki-Koizumi S., Hirakawa T., Inoue T., and Yodoi J. Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span. Antioxid. Redox Signal. 4 (2002) 693-696
-
(2002)
Antioxid. Redox Signal.
, vol.4
, pp. 693-696
-
-
Mitsui, A.1
Hamuro, J.2
Nakamura, H.3
Kondo, N.4
Hirabayashi, Y.5
Ishizaki-Koizumi, S.6
Hirakawa, T.7
Inoue, T.8
Yodoi, J.9
-
159
-
-
33744963806
-
How evolutionary thinking affects people's ideas about aging interventions
-
Mitteldorf J. How evolutionary thinking affects people's ideas about aging interventions. Rejuvenation Res. 9 (2006) 346-350
-
(2006)
Rejuvenation Res.
, vol.9
, pp. 346-350
-
-
Mitteldorf, J.1
-
160
-
-
33744998700
-
Temperature-dependent trade-offs between longevity and fertility in the Drosophila mutant, methuselah
-
Mockett R.J., and Sohal R.S. Temperature-dependent trade-offs between longevity and fertility in the Drosophila mutant, methuselah. Exp. Gerontol. 41 (2006) 566-573
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 566-573
-
-
Mockett, R.J.1
Sohal, R.S.2
-
161
-
-
0037422615
-
Phenotypic effects of familial amyotrophic lateral sclerosis mutant Sod alleles in transgenic Drosophila
-
Mockett R.J., Radyuk S.N., Benes J.J., Orr W.C., and Sohal R.S. Phenotypic effects of familial amyotrophic lateral sclerosis mutant Sod alleles in transgenic Drosophila. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 301-306
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 301-306
-
-
Mockett, R.J.1
Radyuk, S.N.2
Benes, J.J.3
Orr, W.C.4
Sohal, R.S.5
-
162
-
-
0037438869
-
Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity
-
Mockett R.J., Bayne A.C., Kwong L.K., Orr W.C., and Sohal R.S. Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity. Free Radic. Biol. Med. 34 (2003) 207-217
-
(2003)
Free Radic. Biol. Med.
, vol.34
, pp. 207-217
-
-
Mockett, R.J.1
Bayne, A.C.2
Kwong, L.K.3
Orr, W.C.4
Sohal, R.S.5
-
164
-
-
12844267504
-
Methionine sulfoxide reductases: ubiquitous enzymes involved in antioxidant defense, protein regulation, and prevention of aging-associated diseases
-
Moskovitz J. Methionine sulfoxide reductases: ubiquitous enzymes involved in antioxidant defense, protein regulation, and prevention of aging-associated diseases. Biochim. Biophys. Acta 1703 (2005) 213-219
-
(2005)
Biochim. Biophys. Acta
, vol.1703
, pp. 213-219
-
-
Moskovitz, J.1
-
165
-
-
34447316414
-
Trends in oxidative aging theories
-
Muller F.L., Lustgarten M.S., Jang Y., Richardson A., and Van Remmen H. Trends in oxidative aging theories. Free Radic. Biol. Med. 43 (2007) 477-503
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 477-503
-
-
Muller, F.L.1
Lustgarten, M.S.2
Jang, Y.3
Richardson, A.4
Van Remmen, H.5
-
166
-
-
50649085536
-
-
Murphy, M.P., Partridge, L., in press. Toward a control theory analysis of aging. Annu. Rev. Bioch. 77.
-
Murphy, M.P., Partridge, L., in press. Toward a control theory analysis of aging. Annu. Rev. Bioch. 77.
-
-
-
-
167
-
-
34249816807
-
Animal models of tyrosinemia
-
(discussion 1573S-1575S)
-
Nakamura K., Tanaka Y., Mitsubuchi H., and Endo F. Animal models of tyrosinemia. J. Nutr. 137 (2007) 1556S-1560S (discussion 1573S-1575S)
-
(2007)
J. Nutr.
, vol.137
-
-
Nakamura, K.1
Tanaka, Y.2
Mitsubuchi, H.3
Endo, F.4
-
169
-
-
37749001449
-
A bacterial kind of aging
-
Nystrom T. A bacterial kind of aging. PLoS Genet. 3 (2007) e224
-
(2007)
PLoS Genet.
, vol.3
-
-
Nystrom, T.1
-
170
-
-
39449084386
-
Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan
-
O'Brien D.M., Min K.J., Larsen T., and Tatar M. Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan. Curr. Biol. 18 (2008) R155-R156
-
(2008)
Curr. Biol.
, vol.18
-
-
O'Brien, D.M.1
Min, K.J.2
Larsen, T.3
Tatar, M.4
-
171
-
-
33747274956
-
Lifespan extension of Caenorhabditis elegans following repeated mild hormetic heat treatments
-
Olsen A., Vantipalli M.C., and Lithgow G.J. Lifespan extension of Caenorhabditis elegans following repeated mild hormetic heat treatments. Biogerontology 7 (2006) 221-230
-
(2006)
Biogerontology
, vol.7
, pp. 221-230
-
-
Olsen, A.1
Vantipalli, M.C.2
Lithgow, G.J.3
-
172
-
-
0028220114
-
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
Orr W.C., and Sohal R.S. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263 (1994) 1128-1130
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
173
-
-
0037358363
-
Does overexpression of Cu Zn-SOD extend life span in Drosophila melanogaster?
-
Orr W.C., and Sohal R.S. Does overexpression of Cu Zn-SOD extend life span in Drosophila melanogaster?. Exp. Gerontol. 38 (2003) 227-230
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 227-230
-
-
Orr, W.C.1
Sohal, R.S.2
-
174
-
-
0038712734
-
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster
-
Orr W.C., Mockett R.J., Benes J.J., and Sohal R.S. Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster. J. Biol. Chem. 278 (2003) 26418-26422
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26418-26422
-
-
Orr, W.C.1
Mockett, R.J.2
Benes, J.J.3
Sohal, R.S.4
-
175
-
-
34548313690
-
Oxidants and antioxidants revisited new concepts of oxidative stress
-
Packer L., and Cadenas E. Oxidants and antioxidants revisited new concepts of oxidative stress. Free Radic. Res. 41 (2007) 951-952
-
(2007)
Free Radic. Res.
, vol.41
, pp. 951-952
-
-
Packer, L.1
Cadenas, E.2
-
176
-
-
0036236733
-
Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: a homeoviscous-longevity adaptation?
-
Pamplona R., Barja G., and Portero-Otin M. Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: a homeoviscous-longevity adaptation?. Ann. NY Acad. Sci. 959 (2002) 475-490
-
(2002)
Ann. NY Acad. Sci.
, vol.959
, pp. 475-490
-
-
Pamplona, R.1
Barja, G.2
Portero-Otin, M.3
-
177
-
-
2342577555
-
Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain
-
Pamplona R., Portero-Otin M., Sanz A., Requena J., and Barja G. Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain. Exp. Gerontol. 39 (2004) 725-733
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 725-733
-
-
Pamplona, R.1
Portero-Otin, M.2
Sanz, A.3
Requena, J.4
Barja, G.5
-
178
-
-
1542408999
-
Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan
-
Parker J.D., Parker K.M., Sohal B.H., Sohal R.S., and Keller L. Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 3486-3489
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3486-3489
-
-
Parker, J.D.1
Parker, K.M.2
Sohal, B.H.3
Sohal, R.S.4
Keller, L.5
-
179
-
-
48249083981
-
Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential
-
Parker N., Vidal-Puig A.J., and Brand M.D. Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential. Biosci. Rep. 28 (2008) 83-88
-
(2008)
Biosci. Rep.
, vol.28
, pp. 83-88
-
-
Parker, N.1
Vidal-Puig, A.J.2
Brand, M.D.3
-
180
-
-
0031864164
-
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
-
Parkes T.L., Elia A.J., Dickinson D., Hilliker A.J., Phillips J.P., and Boulianne G.L. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat. Genet. 19 (1998) 171-174
-
(1998)
Nat. Genet.
, vol.19
, pp. 171-174
-
-
Parkes, T.L.1
Elia, A.J.2
Dickinson, D.3
Hilliker, A.J.4
Phillips, J.P.5
Boulianne, G.L.6
-
182
-
-
34248137007
-
The ecological stress theory of aging and hormesis: an energetic evolutionary model
-
Parsons P.A. The ecological stress theory of aging and hormesis: an energetic evolutionary model. Biogerontology 8 (2007) 233-242
-
(2007)
Biogerontology
, vol.8
, pp. 233-242
-
-
Parsons, P.A.1
-
183
-
-
36048939348
-
Benchmarks for ageing studies
-
Partridge L., and Gems D. Benchmarks for ageing studies. Nature 450 (2007) 165-167
-
(2007)
Nature
, vol.450
, pp. 165-167
-
-
Partridge, L.1
Gems, D.2
-
184
-
-
0003693103
-
-
University of London Press, London
-
Pearl R. The Rate of Living (1928), University of London Press, London
-
(1928)
The Rate of Living
-
-
Pearl, R.1
-
185
-
-
4444314070
-
Reactions of 4-hydroxynonenal with proteins and cellular targets
-
Petersen D.R., and Doorn J.A. Reactions of 4-hydroxynonenal with proteins and cellular targets. Free Radic. Biol. Med. 37 (2004) 937-945
-
(2004)
Free Radic. Biol. Med.
, vol.37
, pp. 937-945
-
-
Petersen, D.R.1
Doorn, J.A.2
-
186
-
-
0033659765
-
Targeted neuronal expression and longevity in Drosophila
-
Phillips J.P., Parkes T.L., and Hilliker A.J. Targeted neuronal expression and longevity in Drosophila. Exp. Gerontol. 35 (2000) 1157-1164
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 1157-1164
-
-
Phillips, J.P.1
Parkes, T.L.2
Hilliker, A.J.3
-
187
-
-
38349103636
-
Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?
-
Piper M.D., Selman C., McElwee J.J., and Partridge L. Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?. J. Int. Med. 263 (2008) 179-191
-
(2008)
J. Int. Med.
, vol.263
, pp. 179-191
-
-
Piper, M.D.1
Selman, C.2
McElwee, J.J.3
Partridge, L.4
-
189
-
-
45249124663
-
4-Hydroxynonenal: a membrane lipid oxidation product of medicinal interest
-
Poli G., Schaur R.J., Siems W.G., and Leonarduzzi G. 4-Hydroxynonenal: a membrane lipid oxidation product of medicinal interest. Med. Res. Rev. 28 (2008) 569-631
-
(2008)
Med. Res. Rev.
, vol.28
, pp. 569-631
-
-
Poli, G.1
Schaur, R.J.2
Siems, W.G.3
Leonarduzzi, G.4
-
190
-
-
39449118854
-
Fatty acid profile of erythrocyte membranes as possible biomarker of longevity
-
Puca A.A., Andrew P., Novelli V., Anselmi C.V., Somalvico F., Cirillo N.A., Chatgilialoglu C., and Ferreri C. Fatty acid profile of erythrocyte membranes as possible biomarker of longevity. Rejuvenation Res. 11 (2008) 63-72
-
(2008)
Rejuvenation Res.
, vol.11
, pp. 63-72
-
-
Puca, A.A.1
Andrew, P.2
Novelli, V.3
Anselmi, C.V.4
Somalvico, F.5
Cirillo, N.A.6
Chatgilialoglu, C.7
Ferreri, C.8
-
191
-
-
3242775363
-
Slowing down aging from within: mechanistic aspects of anti-aging hormetic effects of mild heat stress on human cells
-
Rattan S.I., Gonzalez-Dosal R., Roge Nielsen E., Kraft D.C., Weibel J., and Kahns S. Slowing down aging from within: mechanistic aspects of anti-aging hormetic effects of mild heat stress on human cells. Acta Biochim. Pol. 51 (2004) 481-492
-
(2004)
Acta Biochim. Pol.
, vol.51
, pp. 481-492
-
-
Rattan, S.I.1
Gonzalez-Dosal, R.2
Roge Nielsen, E.3
Kraft, D.C.4
Weibel, J.5
Kahns, S.6
-
192
-
-
23044445756
-
A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
-
Rea S.L., Wu D., Cypser J.R., Vaupel J.W., and Johnson T.E. A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. Nat. Genet. 37 (2005) 894-898
-
(2005)
Nat. Genet.
, vol.37
, pp. 894-898
-
-
Rea, S.L.1
Wu, D.2
Cypser, J.R.3
Vaupel, J.W.4
Johnson, T.E.5
-
194
-
-
0033885175
-
Action of 2-nonenal and 4-hydroxynonenal on phosphoinositide-specific phospholipase C in undifferentiated and DMSO-differentiated HL-60 cells
-
Rossi M.A., and Dianzani M.U. Action of 2-nonenal and 4-hydroxynonenal on phosphoinositide-specific phospholipase C in undifferentiated and DMSO-differentiated HL-60 cells. Cell Biochem. Funct. 18 (2000) 209-214
-
(2000)
Cell Biochem. Funct.
, vol.18
, pp. 209-214
-
-
Rossi, M.A.1
Dianzani, M.U.2
-
195
-
-
0034785349
-
The benefits and hazards of antioxidants: controlling apoptosis and other protective mechanisms in cancer patients and the human population
-
Salganik R.I. The benefits and hazards of antioxidants: controlling apoptosis and other protective mechanisms in cancer patients and the human population. J. Am. Coll. Nutr. 20 (2001) 464S-472S
-
(2001)
J. Am. Coll. Nutr.
, vol.20
-
-
Salganik, R.I.1
-
196
-
-
33646704229
-
Is the mitochondrial free radical theory of aging intact?
-
Sanz A., Pamplona R., and Barja G. Is the mitochondrial free radical theory of aging intact?. Antioxid. Redox Signal. 8 (2006) 582-599
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 582-599
-
-
Sanz, A.1
Pamplona, R.2
Barja, G.3
-
197
-
-
0037337927
-
Cloning, expression, and biochemical characterization of one Epsilon-class (GST-3) and ten Delta-class (GST-1) glutathione S-transferases from Drosophila melanogaster, and identification of additional nine members of the Epsilon class
-
Sawicki R., Singh S.P., Mondal A.K., Beneš H., and Zimniak P. Cloning, expression, and biochemical characterization of one Epsilon-class (GST-3) and ten Delta-class (GST-1) glutathione S-transferases from Drosophila melanogaster, and identification of additional nine members of the Epsilon class. Biochem. J. 370 (2003) 661-669
-
(2003)
Biochem. J.
, vol.370
, pp. 661-669
-
-
Sawicki, R.1
Singh, S.P.2
Mondal, A.K.3
Beneš, H.4
Zimniak, P.5
-
198
-
-
0021735425
-
Gene amplification in cultured animal cells
-
Schimke R.T. Gene amplification in cultured animal cells. Cell 37 (1984) 705-713
-
(1984)
Cell
, vol.37
, pp. 705-713
-
-
Schimke, R.T.1
-
199
-
-
39749122734
-
The opposing effects of n-3 and n-6 fatty acids
-
Schmitz G., and Ecker J. The opposing effects of n-3 and n-6 fatty acids. Prog. Lipid Res. 47 (2008) 147-155
-
(2008)
Prog. Lipid Res.
, vol.47
, pp. 147-155
-
-
Schmitz, G.1
Ecker, J.2
-
200
-
-
3242704996
-
Autoxidative transformation of chiral ω6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal
-
Schneider C., Porter N.A., and Brash A.R. Autoxidative transformation of chiral ω6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal. Chem. Res. Toxicol. 17 (2004) 937-941
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 937-941
-
-
Schneider, C.1
Porter, N.A.2
Brash, A.R.3
-
201
-
-
53049104634
-
-
Schneider, C., Porter, N.A., Brash, A.R., in press. Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation. J. Biol. Chem.
-
Schneider, C., Porter, N.A., Brash, A.R., in press. Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation. J. Biol. Chem.
-
-
-
-
202
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner S.E., Linford N.J., Martin G.M., Treuting P., Ogburn C.E., Emond M., Coskun P.E., Ladiges W., Wolf N., Van Remmen H., Wallace D.C., and Rabinovitch P.S. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308 (2005) 1909-1911
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
Coskun, P.E.7
Ladiges, W.8
Wolf, N.9
Van Remmen, H.10
Wallace, D.C.11
Rabinovitch, P.S.12
-
203
-
-
34748850786
-
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
-
Schulz T.J., Zarse K., Voigt A., Urban N., Birringer M., and Ristow M. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metabol. 6 (2007) 280-293
-
(2007)
Cell Metabol.
, vol.6
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
204
-
-
0041342065
-
Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium
-
Schutt F., Bergmann M., Holz F.G., and Kopitz J. Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 44 (2003) 3663-3668
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 3663-3668
-
-
Schutt, F.1
Bergmann, M.2
Holz, F.G.3
Kopitz, J.4
-
205
-
-
40449142493
-
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
-
Selman C., Lingard S., Choudhury A.I., Batterham R.L., Claret M., Clements M., Ramadani F., Okkenhaug K., Schuster E., Blanc E., Piper M.D., Al-Qassab H., Speakman J.R., Carmignac D., Robinson I.C., Thornton J.M., Gems D., Partridge L., and Withers D.J. Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB J. 22 (2008) 807-818
-
(2008)
FASEB J.
, vol.22
, pp. 807-818
-
-
Selman, C.1
Lingard, S.2
Choudhury, A.I.3
Batterham, R.L.4
Claret, M.5
Clements, M.6
Ramadani, F.7
Okkenhaug, K.8
Schuster, E.9
Blanc, E.10
Piper, M.D.11
Al-Qassab, H.12
Speakman, J.R.13
Carmignac, D.14
Robinson, I.C.15
Thornton, J.M.16
Gems, D.17
Partridge, L.18
Withers, D.J.19
-
206
-
-
33744915836
-
UCP1 and defence against oxidative stress: 4-hydroxy-2-nonenal effects on brown-fat mitochondria are uncoupling protein 1-independent
-
Shabalina I.G., Petrovic N., Kramarova T.V., Hoeks J., Cannon B., and Nedergaard J. UCP1 and defence against oxidative stress: 4-hydroxy-2-nonenal effects on brown-fat mitochondria are uncoupling protein 1-independent. J. Biol. Chem. 281 (2006) 13882-13893
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 13882-13893
-
-
Shabalina, I.G.1
Petrovic, N.2
Kramarova, T.V.3
Hoeks, J.4
Cannon, B.5
Nedergaard, J.6
-
207
-
-
0024793904
-
Model systems for aging research: syncretic concepts and diversity of mechanisms
-
Shmookler Reis R.J. Model systems for aging research: syncretic concepts and diversity of mechanisms. Genome 31 (1989) 406-412
-
(1989)
Genome
, vol.31
, pp. 406-412
-
-
Shmookler Reis, R.J.1
-
208
-
-
0025271476
-
Clonal variation in gene methylation: c-H-ras and α-hCG regions vary independently in human fibroblast lineages
-
Shmookler Reis R.J., Finn G.K., Smith K., and Goldstein S. Clonal variation in gene methylation: c-H-ras and α-hCG regions vary independently in human fibroblast lineages. Mutat. Res. 237 (1990) 45-57
-
(1990)
Mutat. Res.
, vol.237
, pp. 45-57
-
-
Shmookler Reis, R.J.1
Finn, G.K.2
Smith, K.3
Goldstein, S.4
-
209
-
-
0031459980
-
Extrachromosomal rDNA circles-a cause of aging in yeast
-
Sinclair D.A., and Guarente L. Extrachromosomal rDNA circles-a cause of aging in yeast. Cell 91 (1997) 1033-1042
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
210
-
-
0034833919
-
Catalytic function of Drosophila melanogaster glutathione S-transferase DmGSTS1-1 (GST-2) in conjugation of lipid peroxidation end products
-
Singh S.P., Coronella J.A., Beneš H., Cochrane B.J., and Zimniak P. Catalytic function of Drosophila melanogaster glutathione S-transferase DmGSTS1-1 (GST-2) in conjugation of lipid peroxidation end products. Eur. J. Biochem. 268 (2001) 2912-2923
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2912-2923
-
-
Singh, S.P.1
Coronella, J.A.2
Beneš, H.3
Cochrane, B.J.4
Zimniak, P.5
-
211
-
-
18044367138
-
+/- mouse lymphoma cells
-
+/- mouse lymphoma cells. J. Pharmacol. Exp. Ther. 313 (2005) 855-861
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.313
, pp. 855-861
-
-
Singh, S.P.1
Chen, T.2
Chen, L.3
Mei, N.4
McLain, E.5
Samokyszyn, V.6
Thaden, J.J.7
Moore, M.M.8
Zimniak, P.9
-
213
-
-
0027442218
-
Biochemical correlates of longevity in two closely related rodent species
-
Sohal R.S., Ku H.H., and Agarwal S. Biochemical correlates of longevity in two closely related rodent species. Biochem. Biophys. Res. Commun. 196 (1993) 7-11
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.196
, pp. 7-11
-
-
Sohal, R.S.1
Ku, H.H.2
Agarwal, S.3
-
214
-
-
0027328852
-
Protein oxidative damage is associated with life expectancy of houseflies
-
Sohal R.S., Agarwal S., Dubey A., and Orr W.C. Protein oxidative damage is associated with life expectancy of houseflies. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 7255-7259
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 7255-7259
-
-
Sohal, R.S.1
Agarwal, S.2
Dubey, A.3
Orr, W.C.4
-
215
-
-
0036710886
-
Mechanisms of aging: an appraisal of the oxidative stress hypothesis
-
Sohal R.S., Mockett R.J., and Orr W.C. Mechanisms of aging: an appraisal of the oxidative stress hypothesis. Free Radic. Biol. Med. 33 (2002) 575-586
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 575-586
-
-
Sohal, R.S.1
Mockett, R.J.2
Orr, W.C.3
-
216
-
-
0028949615
-
Proteins and temperature
-
Somero G.N. Proteins and temperature. Annu. Rev. Physiol. 57 (1995) 43-68
-
(1995)
Annu. Rev. Physiol.
, vol.57
, pp. 43-68
-
-
Somero, G.N.1
-
217
-
-
0033524494
-
Structural and kinetic determinants of aldehyde reduction by aldose reductase
-
Srivastava S., Watowich S.J., Petrash J.M., Srivastava S.K., and Bhatnagar A. Structural and kinetic determinants of aldehyde reduction by aldose reductase. Biochemistry 38 (1999) 42-54
-
(1999)
Biochemistry
, vol.38
, pp. 42-54
-
-
Srivastava, S.1
Watowich, S.J.2
Petrash, J.M.3
Srivastava, S.K.4
Bhatnagar, A.5
-
218
-
-
33750710080
-
Protein oxidation and aging
-
Stadtman E.R. Protein oxidation and aging. Free Radic. Res. 40 (2006) 1250-1258
-
(2006)
Free Radic. Res.
, vol.40
, pp. 1250-1258
-
-
Stadtman, E.R.1
-
219
-
-
13944272143
-
Aging and death in an organism that reproduces by morphologically symmetric division
-
Stewart E.J., Madden R., Paul G., and Taddei F. Aging and death in an organism that reproduces by morphologically symmetric division. PLoS Biol. 3 (2005) e45
-
(2005)
PLoS Biol.
, vol.3
-
-
Stewart, E.J.1
Madden, R.2
Paul, G.3
Taddei, F.4
-
220
-
-
53049095140
-
-
Sulzer, D., Mosharov, E., Talloczy, Z., Zucca, F.A., Simon, J.D., Zecca, L., in press. Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease. J. Neurochem.
-
Sulzer, D., Mosharov, E., Talloczy, Z., Zucca, F.A., Simon, J.D., Zecca, L., in press. Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease. J. Neurochem.
-
-
-
-
221
-
-
0032908347
-
FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
-
Sun J., and Tower J. FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies. Mol. Cell Biol. 19 (1999) 216-228
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 216-228
-
-
Sun, J.1
Tower, J.2
-
222
-
-
2442584381
-
Oxidative fragmentation of hydroxy octadecadienoates generates biologically active γ-hydroxyalkenals
-
Sun M., and Salomon R.G. Oxidative fragmentation of hydroxy octadecadienoates generates biologically active γ-hydroxyalkenals. J. Am. Chem. Soc. 126 (2004) 5699-5708
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 5699-5708
-
-
Sun, M.1
Salomon, R.G.2
-
223
-
-
0035815445
-
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
-
Tatar M., Kopelman A., Epstein D., Tu M.P., Yin C.M., and Garofalo R.S. A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292 (2001) 107-110
-
(2001)
Science
, vol.292
, pp. 107-110
-
-
Tatar, M.1
Kopelman, A.2
Epstein, D.3
Tu, M.P.4
Yin, C.M.5
Garofalo, R.S.6
-
224
-
-
33744488281
-
Catabolic insufficiency and aging
-
Terman A. Catabolic insufficiency and aging. Ann. NY Acad. Sci. 1067 (2006) 27-36
-
(2006)
Ann. NY Acad. Sci.
, vol.1067
, pp. 27-36
-
-
Terman, A.1
-
225
-
-
0036007110
-
Model organisms as a guide to mammalian aging
-
Tissenbaum H.A., and Guarente L. Model organisms as a guide to mammalian aging. Dev. Cell 2 (2002) 9-19
-
(2002)
Dev. Cell
, vol.2
, pp. 9-19
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
226
-
-
0032493431
-
Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine
-
Tsai L., Szweda P.A., Vinogradova O., and Szweda L.I. Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 7975-7980
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 7975-7980
-
-
Tsai, L.1
Szweda, P.A.2
Vinogradova, O.3
Szweda, L.I.4
-
227
-
-
36249018862
-
4-Hydroxy-2-nonenal-modified glyceraldehyde-3-phosphate dehydrogenase is degraded by cathepsin G
-
Tsuchiya Y., Okuno Y., Hishinuma K., Ezaki A., Okada G., Yamaguchi M., Chikuma T., and Hojo H. 4-Hydroxy-2-nonenal-modified glyceraldehyde-3-phosphate dehydrogenase is degraded by cathepsin G. Free Radic. Biol. Med. 43 (2007) 1604-1615
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 1604-1615
-
-
Tsuchiya, Y.1
Okuno, Y.2
Hishinuma, K.3
Ezaki, A.4
Okada, G.5
Yamaguchi, M.6
Chikuma, T.7
Hojo, H.8
-
228
-
-
0037411282
-
4-Hydroxy-2-nonenal: a product and mediator of oxidative stress
-
Uchida K. 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. Prog. Lipid Res. 42 (2003) 318-343
-
(2003)
Prog. Lipid Res.
, vol.42
, pp. 318-343
-
-
Uchida, K.1
-
229
-
-
33750686243
-
Lipofuscin-like fluorophores originated from malondialdehyde
-
Uchida K. Lipofuscin-like fluorophores originated from malondialdehyde. Free Radic. Res. 40 (2006) 1335-1338
-
(2006)
Free Radic. Res.
, vol.40
, pp. 1335-1338
-
-
Uchida, K.1
-
230
-
-
0026606054
-
Modification of histidine residues in proteins by reaction with 4-hydroxynonenal
-
Uchida K., and Stadtman E.R. Modification of histidine residues in proteins by reaction with 4-hydroxynonenal. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 4544-4548
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 4544-4548
-
-
Uchida, K.1
Stadtman, E.R.2
-
231
-
-
0027326559
-
Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes
-
Uchida K., Szweda L.I., Chae H.-Z., and Stadtman E.R. Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 8742-8746
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 8742-8746
-
-
Uchida, K.1
Szweda, L.I.2
Chae, H.-Z.3
Stadtman, E.R.4
-
232
-
-
2442628362
-
The case for negative senescence
-
Vaupel J.W., Baudisch A., Dolling M., Roach D.A., and Gampe J. The case for negative senescence. Theor. Popul. Biol. 65 (2004) 339-351
-
(2004)
Theor. Popul. Biol.
, vol.65
, pp. 339-351
-
-
Vaupel, J.W.1
Baudisch, A.2
Dolling, M.3
Roach, D.A.4
Gampe, J.5
-
233
-
-
34047116291
-
Mitochondrial point mutations do not limit the natural lifespan of mice
-
Vermulst M., Bielas J.H., Kujoth G.C., Ladiges W.C., Rabinovitch P.S., Prolla T.A., and Loeb L.A. Mitochondrial point mutations do not limit the natural lifespan of mice. Nat. Genet. 39 (2007) 540-543
-
(2007)
Nat. Genet.
, vol.39
, pp. 540-543
-
-
Vermulst, M.1
Bielas, J.H.2
Kujoth, G.C.3
Ladiges, W.C.4
Rabinovitch, P.S.5
Prolla, T.A.6
Loeb, L.A.7
-
234
-
-
0030885545
-
Bathymetric demography, enzyme activity patterns, and bioenergetics of deep-living scorpaenig fishes (genera Sebastes and Sebastolobus): paradigms revisited
-
Vetter R.D., and Lynn E.A. Bathymetric demography, enzyme activity patterns, and bioenergetics of deep-living scorpaenig fishes (genera Sebastes and Sebastolobus): paradigms revisited. Mar. Ecol. Prog. Ser. 155 (1997) 173-188
-
(1997)
Mar. Ecol. Prog. Ser.
, vol.155
, pp. 173-188
-
-
Vetter, R.D.1
Lynn, E.A.2
-
235
-
-
53049103000
-
-
Vijg, J., in press. The role of DNA damage and repair in aging: New approaches to an old problem. Mech. Ageing Dev.
-
Vijg, J., in press. The role of DNA damage and repair in aging: New approaches to an old problem. Mech. Ageing Dev.
-
-
-
-
236
-
-
41649118986
-
Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives
-
Vila A., Tallman K.A., Jacobs A.T., Liebler D.C., Porter N.A., and Marnett L.J. Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives. Chem. Res. Toxicol. 21 (2008) 432-444
-
(2008)
Chem. Res. Toxicol.
, vol.21
, pp. 432-444
-
-
Vila, A.1
Tallman, K.A.2
Jacobs, A.T.3
Liebler, D.C.4
Porter, N.A.5
Marnett, L.J.6
-
237
-
-
33645902496
-
Dietary manipulation implicates lipid signaling in the regulation of germ cell maintenance in C. elegans
-
Watts J.L., and Browse J. Dietary manipulation implicates lipid signaling in the regulation of germ cell maintenance in C. elegans. Dev. Biol. 292 (2006) 381-392
-
(2006)
Dev. Biol.
, vol.292
, pp. 381-392
-
-
Watts, J.L.1
Browse, J.2
-
238
-
-
33750706163
-
Mitochondrial DNA damage and the aging process-facts and imaginations
-
Wiesner R.J., Zsurka G., and Kunz W.S. Mitochondrial DNA damage and the aging process-facts and imaginations. Free Radic. Res. 40 (2006) 1284-1294
-
(2006)
Free Radic. Res.
, vol.40
, pp. 1284-1294
-
-
Wiesner, R.J.1
Zsurka, G.2
Kunz, W.S.3
-
239
-
-
0000055057
-
Pleiotropy, natural selection, and the evolution of senescence
-
Williams G.C. Pleiotropy, natural selection, and the evolution of senescence. Evolution 11 (1957) 398-411
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
Williams, G.C.1
-
240
-
-
0038148579
-
Reproduction and resistance to stress: when and how
-
Wingfield J.C., and Sapolsky R.M. Reproduction and resistance to stress: when and how. J. Neuroendocrinol. 15 (2003) 711-724
-
(2003)
J. Neuroendocrinol.
, vol.15
, pp. 711-724
-
-
Wingfield, J.C.1
Sapolsky, R.M.2
-
241
-
-
0034282230
-
Biomarkers of myeloperoxidase-derived hypochlorous acid
-
Winterbourn C.C., and Kettle A.J. Biomarkers of myeloperoxidase-derived hypochlorous acid. Free Radic. Biol. Med. 29 (2000) 403-409
-
(2000)
Free Radic. Biol. Med.
, vol.29
, pp. 403-409
-
-
Winterbourn, C.C.1
Kettle, A.J.2
-
242
-
-
33646785765
-
Uncoupling protein homologs may provide a link between mitochondria, metabolism and lifespan
-
Wolkow C.A., and Iser W.B. Uncoupling protein homologs may provide a link between mitochondria, metabolism and lifespan. Ageing Res. Rev. 5 (2006) 196-208
-
(2006)
Ageing Res. Rev.
, vol.5
, pp. 196-208
-
-
Wolkow, C.A.1
Iser, W.B.2
-
243
-
-
33744456501
-
Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress
-
Yang X., Doser T.A., Fang C.X., Nunn J.M., Janardhanan R., Zhu M., Sreejayan N., Quinn M.T., and Ren J. Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress. FASEB J. 20 (2006) 1024-1026
-
(2006)
FASEB J.
, vol.20
, pp. 1024-1026
-
-
Yang, X.1
Doser, T.A.2
Fang, C.X.3
Nunn, J.M.4
Janardhanan, R.5
Zhu, M.6
Sreejayan, N.7
Quinn, M.T.8
Ren, J.9
-
244
-
-
53049109716
-
Substrates and reaction mechanisms of GSTs
-
Awasthi Y.C. (Ed), CRC Press, Boca Raton, FL
-
Zimniak P. Substrates and reaction mechanisms of GSTs. In: Awasthi Y.C. (Ed). Toxicology of Glutathione Transferases (2006), CRC Press, Boca Raton, FL 71-101
-
(2006)
Toxicology of Glutathione Transferases
, pp. 71-101
-
-
Zimniak, P.1
-
245
-
-
41149147430
-
Families of glutathione transferases
-
Awasthi Y.C. (Ed), CRC Press, Boca Raton, FL
-
Zimniak P., and Singh S.P. Families of glutathione transferases. In: Awasthi Y.C. (Ed). Toxicology of Glutathione Transferases (2006), CRC Press, Boca Raton, FL 11-26
-
(2006)
Toxicology of Glutathione Transferases
, pp. 11-26
-
-
Zimniak, P.1
Singh, S.P.2
-
246
-
-
0028069416
-
Estimation of genomic complexity, heterologous expression, and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5. 7)
-
Zimniak P., Singhal S.S., Srivastava S.K., Awasthi S., Sharma R., Hayden J.B., and Awasthi Y.C. Estimation of genomic complexity, heterologous expression, and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5. 7). J. Biol. Chem. 269 (1994) 992-1000
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 992-1000
-
-
Zimniak, P.1
Singhal, S.S.2
Srivastava, S.K.3
Awasthi, S.4
Sharma, R.5
Hayden, J.B.6
Awasthi, Y.C.7
|