-
1
-
-
0033197996
-
The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses
-
Abbott M.A., Wells D.G., and Fallon J.R. The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses. J. Neurosci. 19 (1999) 7300-7308
-
(1999)
J. Neurosci.
, vol.19
, pp. 7300-7308
-
-
Abbott, M.A.1
Wells, D.G.2
Fallon, J.R.3
-
2
-
-
0142184484
-
Proteasome-dependent decrease in Akt by growth factors in vascular smooth muscle cells
-
Adachi M., Katsumura K.R., Fujii K., Kobayashi S., Aoki H., and Matsuzaki M. Proteasome-dependent decrease in Akt by growth factors in vascular smooth muscle cells. FEBS Lett. 554 (2003) 77-80
-
(2003)
FEBS Lett.
, vol.554
, pp. 77-80
-
-
Adachi, M.1
Katsumura, K.R.2
Fujii, K.3
Kobayashi, S.4
Aoki, H.5
Matsuzaki, M.6
-
3
-
-
12144288368
-
Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD
-
Ahmadian G., Ju W., Liu L., Wyszynski M., Lee S.H., Dunah A.W., Taghibiglou C., Wang Y., Lu J., Wong T.P., Sheng M., and Wang Y.T. Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD. EMBO J. 23 (2004) 1040-1050
-
(2004)
EMBO J.
, vol.23
, pp. 1040-1050
-
-
Ahmadian, G.1
Ju, W.2
Liu, L.3
Wyszynski, M.4
Lee, S.H.5
Dunah, A.W.6
Taghibiglou, C.7
Wang, Y.8
Lu, J.9
Wong, T.P.10
Sheng, M.11
Wang, Y.T.12
-
4
-
-
85047681190
-
Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture
-
Alessi D.R. Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture. Biochem. Soc. Trans. 29 (2001) 1-14
-
(2001)
Biochem. Soc. Trans.
, vol.29
, pp. 1-14
-
-
Alessi, D.R.1
-
5
-
-
0025078744
-
Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex
-
Artola A., Brocher S., and Singer W. Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex. Nature 347 (1990) 69-72
-
(1990)
Nature
, vol.347
, pp. 69-72
-
-
Artola, A.1
Brocher, S.2
Singer, W.3
-
7
-
-
1842734659
-
The source of cerebral insulin
-
Banks W.A. The source of cerebral insulin. Eur. J. Pharmacol. 490 (2004) 5-12
-
(2004)
Eur. J. Pharmacol.
, vol.490
, pp. 5-12
-
-
Banks, W.A.1
-
8
-
-
0023161139
-
Insulin in the brain
-
Baskin D.G., Figlewicz D.P., Woods S.C., Porte Jr. D., and Dorsa D.M. Insulin in the brain. Annu. Rev. Physiol. 49 (1987) 335-347
-
(1987)
Annu. Rev. Physiol.
, vol.49
, pp. 335-347
-
-
Baskin, D.G.1
Figlewicz, D.P.2
Woods, S.C.3
Porte Jr., D.4
Dorsa, D.M.5
-
10
-
-
0020562895
-
Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid
-
Baskin D.G., Woods S.C., West D.B., van Houten M., Posner B.I., Dorsa D.M., and Porte Jr. D. Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid. Endocrinology 113 (1983) 1818-1825
-
(1983)
Endocrinology
, vol.113
, pp. 1818-1825
-
-
Baskin, D.G.1
Woods, S.C.2
West, D.B.3
van Houten, M.4
Posner, B.I.5
Dorsa, D.M.6
Porte Jr., D.7
-
11
-
-
0033955680
-
High glucose and insulin inhibit VSMC MKP-1 expression by blocking iNOS via p38 MAPK activation
-
Begum N., and Ragolia L. High glucose and insulin inhibit VSMC MKP-1 expression by blocking iNOS via p38 MAPK activation. Am. J. Physiol. Cell Physiol. 278 (2000) C81-C91
-
(2000)
Am. J. Physiol. Cell Physiol.
, vol.278
-
-
Begum, N.1
Ragolia, L.2
-
12
-
-
0034711206
-
Degradation of amylin by insulin-degrading enzyme
-
Bennett R.G., Duckworth W.C., and Hamel F.G. Degradation of amylin by insulin-degrading enzyme. J. Biol. Chem. 275 (2000) 36621-36625
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36621-36625
-
-
Bennett, R.G.1
Duckworth, W.C.2
Hamel, F.G.3
-
13
-
-
0034704198
-
Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
-
Bertram L., Blacker D., Mullin K., Keeney D., Jones J., Basu S., Yhu S., Mclnnis M.G., Go R.C., Vekrellis K., Selkoe D.J., Saunders A.J., and Tanzi R.E. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science 290 (2000) 2302-2303
-
(2000)
Science
, vol.290
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
Yhu, S.7
Mclnnis, M.G.8
Go, R.C.9
Vekrellis, K.10
Selkoe, D.J.11
Saunders, A.J.12
Tanzi, R.E.13
-
14
-
-
29044449855
-
Risk of dementia in diabetes mellitus: a systematic review
-
Biessels G.J., Staekenborg S., Brunner E., Brayne C., and Scheltens P. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol. 5 (2006) 64-74
-
(2006)
Lancet Neurol.
, vol.5
, pp. 64-74
-
-
Biessels, G.J.1
Staekenborg, S.2
Brunner, E.3
Brayne, C.4
Scheltens, P.5
-
15
-
-
0037134269
-
Ageing and diabetes: implications for brain function
-
Biessels G.J., van der Heide L.P., Kamal A., Bleys R.L., and Gispen W.H. Ageing and diabetes: implications for brain function. Eur. J. Pharmacol. 441 (2002) 1-14
-
(2002)
Eur. J. Pharmacol.
, vol.441
, pp. 1-14
-
-
Biessels, G.J.1
van der Heide, L.P.2
Kamal, A.3
Bleys, R.L.4
Gispen, W.H.5
-
16
-
-
85047698627
-
Sniffing neuropeptides: a transnasal approach to the human brain
-
Born J., Lange T., Kern W., McGregor G.P., Bickel U., and Fehm H.L. Sniffing neuropeptides: a transnasal approach to the human brain. Nat. Neurosci. 5 (2002) 514-516
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 514-516
-
-
Born, J.1
Lange, T.2
Kern, W.3
McGregor, G.P.4
Bickel, U.5
Fehm, H.L.6
-
17
-
-
0035369623
-
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
-
Brunet A., Datta S.R., and Greenberg M.E. Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr. Opin. Neurobiol. 11 (2001) 297-305
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, pp. 297-305
-
-
Brunet, A.1
Datta, S.R.2
Greenberg, M.E.3
-
18
-
-
33644968179
-
Insulin degrading enzyme and alpha-3 catenin polymorphisms in Italian patients with Alzheimer disease
-
Cellini E., Bagnoli S., Tedde A., Nacmias B., Piacentini S., and Sorbi S. Insulin degrading enzyme and alpha-3 catenin polymorphisms in Italian patients with Alzheimer disease. Alzheimer Dis. Assoc. Disord. 19 (2005) 246-247
-
(2005)
Alzheimer Dis. Assoc. Disord.
, vol.19
, pp. 246-247
-
-
Cellini, E.1
Bagnoli, S.2
Tedde, A.3
Nacmias, B.4
Piacentini, S.5
Sorbi, S.6
-
19
-
-
24944532213
-
PI3 kinase signaling is required for retrieval and extinction of contextual memory
-
Chen X., Garelick M.G., Wang H., Lil V., Athos J., and Storm D.R. PI3 kinase signaling is required for retrieval and extinction of contextual memory. Nat. Neurosci. 8 (2005) 925-931
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 925-931
-
-
Chen, X.1
Garelick, M.G.2
Wang, H.3
Lil, V.4
Athos, J.5
Storm, D.R.6
-
20
-
-
0021189287
-
Insulin binds to specific receptors and stimulates 2-deoxy-d-glucose uptake in cultured glial cells from rat brain
-
Clarke D.W., Boyd Jr. F.T., Kappy M.S., and Raizada M.K. Insulin binds to specific receptors and stimulates 2-deoxy-d-glucose uptake in cultured glial cells from rat brain. J. Biol. Chem. 259 (1984) 11672-11675
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 11672-11675
-
-
Clarke, D.W.1
Boyd Jr., F.T.2
Kappy, M.S.3
Raizada, M.K.4
-
21
-
-
0038177803
-
Insulin dose-response effects on memory and plasma amyloid precursor protein in Alzheimer's disease: interactions with apolipoprotein E genotype
-
Craft S., Asthana S., Cook D.G., Baker L.D., Cherrier M., Purganan K., Wait C., Petrova A., Latendresse S., Watson G.S., Newcomer J.W., Schellenberg G.D., and Krohn A.J. Insulin dose-response effects on memory and plasma amyloid precursor protein in Alzheimer's disease: interactions with apolipoprotein E genotype. Psychoneuroendocrinology 28 (2003) 809-822
-
(2003)
Psychoneuroendocrinology
, vol.28
, pp. 809-822
-
-
Craft, S.1
Asthana, S.2
Cook, D.G.3
Baker, L.D.4
Cherrier, M.5
Purganan, K.6
Wait, C.7
Petrova, A.8
Latendresse, S.9
Watson, G.S.10
Newcomer, J.W.11
Schellenberg, G.D.12
Krohn, A.J.13
-
22
-
-
0032737079
-
Enhancement of memory in Alzheimer disease with insulin and somatostatin, but not glucose
-
Craft S., Asthana S., Newcomer J.W., Wilkinson C.W., Matos I.T., Baker L.D., Cherrier M., Lofgreen C., Latendresse S., Petrova A., Plymate S., Raskind M., Grimwood K., and Veith R.C. Enhancement of memory in Alzheimer disease with insulin and somatostatin, but not glucose. Arch. Gen. Psychiatry 56 (1999) 1135-1140
-
(1999)
Arch. Gen. Psychiatry
, vol.56
, pp. 1135-1140
-
-
Craft, S.1
Asthana, S.2
Newcomer, J.W.3
Wilkinson, C.W.4
Matos, I.T.5
Baker, L.D.6
Cherrier, M.7
Lofgreen, C.8
Latendresse, S.9
Petrova, A.10
Plymate, S.11
Raskind, M.12
Grimwood, K.13
Veith, R.C.14
-
23
-
-
0030053556
-
Memory improvement following induced hyperinsulinemia in Alzheimer's disease
-
Craft S., Newcomer J., Kanne S., Dagogo-Jack S., Cryer P., Sheline Y., Luby J., Dagogo-Jack A., and Alderson A. Memory improvement following induced hyperinsulinemia in Alzheimer's disease. Neurobiol. Aging 17 (1996) 123-130
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 123-130
-
-
Craft, S.1
Newcomer, J.2
Kanne, S.3
Dagogo-Jack, S.4
Cryer, P.5
Sheline, Y.6
Luby, J.7
Dagogo-Jack, A.8
Alderson, A.9
-
24
-
-
0031907459
-
Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype
-
Craft S., Peskind E., Schwartz M.W., Schellenberg G.D., Raskind M., and Porte Jr. D. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology 50 (1998) 164-168
-
(1998)
Neurology
, vol.50
, pp. 164-168
-
-
Craft, S.1
Peskind, E.2
Schwartz, M.W.3
Schellenberg, G.D.4
Raskind, M.5
Porte Jr., D.6
-
25
-
-
1242316296
-
Insulin and neurodegenerative disease: shared and specific mechanisms
-
Craft S., and Watson G.S. Insulin and neurodegenerative disease: shared and specific mechanisms. Lancet Neurol. 3 (2004) 169-178
-
(2004)
Lancet Neurol.
, vol.3
, pp. 169-178
-
-
Craft, S.1
Watson, G.S.2
-
26
-
-
0032752063
-
Cellular survival: a play in three Akts
-
Datta S.R., Brunet A., and Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev. 13 (1999) 2905-2927
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
27
-
-
0027398295
-
Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo
-
Deltour L., Leduque P., Blume N., Madsen O., Dubois P., Jami J., and Bucchini D. Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 527-531
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 527-531
-
-
Deltour, L.1
Leduque, P.2
Blume, N.3
Madsen, O.4
Dubois, P.5
Jami, J.6
Bucchini, D.7
-
28
-
-
0028958086
-
Tissue- and developmental stage-specific imprinting of the mouse proinsulin gene, Ins2
-
Deltour L., Montagutelli X., Guenet J.L., Jami J., and Paldi A. Tissue- and developmental stage-specific imprinting of the mouse proinsulin gene, Ins2. Dev. Biol. 168 (1995) 686-688
-
(1995)
Dev. Biol.
, vol.168
, pp. 686-688
-
-
Deltour, L.1
Montagutelli, X.2
Guenet, J.L.3
Jami, J.4
Paldi, A.5
-
29
-
-
0022376346
-
Insulin antibodies retard and insulin accelerates growth and differentiation in early embryos
-
de Pablo F., Girbau M., Gomez J.A., Hernandez E., and Roth J. Insulin antibodies retard and insulin accelerates growth and differentiation in early embryos. Diabetes 34 (1985) 1063-1067
-
(1985)
Diabetes
, vol.34
, pp. 1063-1067
-
-
de Pablo, F.1
Girbau, M.2
Gomez, J.A.3
Hernandez, E.4
Roth, J.5
-
30
-
-
0028310417
-
Insulin gene expression and insulin synthesis in mammalian neuronal cells
-
Devaskar S.U., Giddings S.J., Rajakumar P.A., Carnaghi L.R., Menon R.K., and Zahm D.S. Insulin gene expression and insulin synthesis in mammalian neuronal cells. J. Biol. Chem. 269 (1994) 8445-8454
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8445-8454
-
-
Devaskar, S.U.1
Giddings, S.J.2
Rajakumar, P.A.3
Carnaghi, L.R.4
Menon, R.K.5
Zahm, D.S.6
-
31
-
-
0038024467
-
Development. Wiring the brain with insulin
-
Dickson B.J. Development. Wiring the brain with insulin. Science 300 (2003) 440-441
-
(2003)
Science
, vol.300
, pp. 440-441
-
-
Dickson, B.J.1
-
32
-
-
0033605420
-
Protein kinase Czeta is a negative regulator of protein kinase B activity
-
Doornbos R.P., Theelen M., van der Hoeven P.C., van Blitterswijk W.J., Verkleij A.J., and van Bergen en Henegouwen P.M. Protein kinase Czeta is a negative regulator of protein kinase B activity. J. Biol. Chem. 21A (1999) 8589-8596
-
(1999)
J. Biol. Chem.
, vol.21 A
, pp. 8589-8596
-
-
Doornbos, R.P.1
Theelen, M.2
van der Hoeven, P.C.3
van Blitterswijk, W.J.4
Verkleij, A.J.5
van Bergen en Henegouwen, P.M.6
-
33
-
-
0026579349
-
Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-d-aspartate receptor blockade
-
Dudek S.M., and Bear M.F. Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-d-aspartate receptor blockade. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 4363-4367
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 4363-4367
-
-
Dudek, S.M.1
Bear, M.F.2
-
34
-
-
0027195617
-
Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus
-
Dudek S.M., and Bear M.F. Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus. J. Neurosci. 13 (1993) 2910-2918
-
(1993)
J. Neurosci.
, vol.13
, pp. 2910-2918
-
-
Dudek, S.M.1
Bear, M.F.2
-
35
-
-
0017904295
-
Long-term potentiation and depression of synaptic responses in the rat hippocampus: localization and frequency dependency
-
Dunwiddie T., and Lynch G. Long-term potentiation and depression of synaptic responses in the rat hippocampus: localization and frequency dependency. J. Physiol. 276 (1978) 353-367
-
(1978)
J. Physiol.
, vol.276
, pp. 353-367
-
-
Dunwiddie, T.1
Lynch, G.2
-
36
-
-
0017807993
-
Synaptic transmission is required for initiation of long-term potentiation
-
Dunwiddie T., Madison D., and Lynch G. Synaptic transmission is required for initiation of long-term potentiation. Brain Res. 150 (1978) 413-417
-
(1978)
Brain Res.
, vol.150
, pp. 413-417
-
-
Dunwiddie, T.1
Madison, D.2
Lynch, G.3
-
37
-
-
1642290835
-
Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein
-
Farris W., Mansourian S., Leissring M.A., Eckman E.A., Bertram L., Eckman C.B., Tanzi R.E., and Selkoe D.J. Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am. J. Pathol. 164 (2004) 1425-1434
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 1425-1434
-
-
Farris, W.1
Mansourian, S.2
Leissring, M.A.3
Eckman, E.A.4
Bertram, L.5
Eckman, C.B.6
Tanzi, R.E.7
Selkoe, D.J.8
-
38
-
-
15444339756
-
Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease
-
Frolich L., Blum-Degen D., Bernstein H.G., Engelsberger S., Humrich J., Laufer S., Muschner D., Thalheimer A., Turk A., Hoyer S., Zochling R., Boissl K.W., Jellinger K., and Riederer P. Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease. J. Neural Transm. 105 (1998) 423-438
-
(1998)
J. Neural Transm.
, vol.105
, pp. 423-438
-
-
Frolich, L.1
Blum-Degen, D.2
Bernstein, H.G.3
Engelsberger, S.4
Humrich, J.5
Laufer, S.6
Muschner, D.7
Thalheimer, A.8
Turk, A.9
Hoyer, S.10
Zochling, R.11
Boissl, K.W.12
Jellinger, K.13
Riederer, P.14
-
39
-
-
24744460940
-
Transcriptional regulation of neuronal genes and its effect on neural functions: expression and function of forkhead transcription factors in neurons
-
Fukunaga K., Ishigami T., and Kawano T. Transcriptional regulation of neuronal genes and its effect on neural functions: expression and function of forkhead transcription factors in neurons. J. Pharmacol. Sci. 98 (2005) 205-211
-
(2005)
J. Pharmacol. Sci.
, vol.98
, pp. 205-211
-
-
Fukunaga, K.1
Ishigami, T.2
Kawano, T.3
-
40
-
-
0029943447
-
Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein
-
Garrity P.A., Rao Y., Salecker I., McGlade J., Pawson T., and Zipursky S.L. Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein. Cell 85 (1996) 639-650
-
(1996)
Cell
, vol.85
, pp. 639-650
-
-
Garrity, P.A.1
Rao, Y.2
Salecker, I.3
McGlade, J.4
Pawson, T.5
Zipursky, S.L.6
-
41
-
-
0021832368
-
Glucose regulated insulin biosynthesis in isolated rat pancreatic islets is accompanied by changes in proinsulin mRNA
-
Giddings S.J., Chirgwin J.M., and Permutt M.A. Glucose regulated insulin biosynthesis in isolated rat pancreatic islets is accompanied by changes in proinsulin mRNA. Diab. Res. 2 (1985) 71-75
-
(1985)
Diab. Res.
, vol.2
, pp. 71-75
-
-
Giddings, S.J.1
Chirgwin, J.M.2
Permutt, M.A.3
-
42
-
-
0042477712
-
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
-
Gilley J., Coffer P.J., and Ham J. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J. Cell. Biol. 162 (2003) 613-622
-
(2003)
J. Cell. Biol.
, vol.162
, pp. 613-622
-
-
Gilley, J.1
Coffer, P.J.2
Ham, J.3
-
43
-
-
0034333018
-
Cognition and synaptic plasticity in diabetes mellitus
-
Gispen W.H., and Biessels G.J. Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci. 23 (2000) 542-549
-
(2000)
Trends Neurosci.
, vol.23
, pp. 542-549
-
-
Gispen, W.H.1
Biessels, G.J.2
-
44
-
-
0026784678
-
Heterogeneity of messenger RNA that encodes the rat insulin receptor is limited to the domain of exon 11. Analysis by RNA heteroduplex mapping, amplification of cDNA, and in vitro translation
-
Goldstein B.J., and Dudley A.L. Heterogeneity of messenger RNA that encodes the rat insulin receptor is limited to the domain of exon 11. Analysis by RNA heteroduplex mapping, amplification of cDNA, and in vitro translation. Diabetes 41 (1992) 1293-1300
-
(1992)
Diabetes
, vol.41
, pp. 1293-1300
-
-
Goldstein, B.J.1
Dudley, A.L.2
-
45
-
-
12444282662
-
Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility
-
Groves C.J., Wiltshire S., Smedley D., Owen K.R., Frayling T.M., Walker M., Hitman G.A., Levy J.C., O'Rahilly S., Menzel S., Hattersley A.T., and McCarthy M.I. Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility. Diabetes 52 (2003) 1300-1305
-
(2003)
Diabetes
, vol.52
, pp. 1300-1305
-
-
Groves, C.J.1
Wiltshire, S.2
Smedley, D.3
Owen, K.R.4
Frayling, T.M.5
Walker, M.6
Hitman, G.A.7
Levy, J.C.8
O'Rahilly, S.9
Menzel, S.10
Hattersley, A.T.11
McCarthy, M.I.12
-
46
-
-
29044449313
-
N-Methyl-d-aspartate (NMDA) and the regulation of mitogen-activated protein kinase (MAPK) signaling pathways: a revolving neurochemical axis for therapeutic intervention?
-
Haddad J.J. N-Methyl-d-aspartate (NMDA) and the regulation of mitogen-activated protein kinase (MAPK) signaling pathways: a revolving neurochemical axis for therapeutic intervention?. Prog. Neurobiol. 11 (2005) 252-282
-
(2005)
Prog. Neurobiol.
, vol.11
, pp. 252-282
-
-
Haddad, J.J.1
-
48
-
-
0035081161
-
The genetic causes of neurodegenerative diseases
-
Hardy J. The genetic causes of neurodegenerative diseases. J. Alzheimers Dis. 3 (2001) 109-116
-
(2001)
J. Alzheimers Dis.
, vol.3
, pp. 109-116
-
-
Hardy, J.1
-
49
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297 (2002) 353-356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
50
-
-
0019458387
-
Insulin and insulin-receptors in rodent brain
-
Havrankova J., Brownstein M., and Roth J. Insulin and insulin-receptors in rodent brain. Diabetologia 20 (1981) 268-273
-
(1981)
Diabetologia
, vol.20
, pp. 268-273
-
-
Havrankova, J.1
Brownstein, M.2
Roth, J.3
-
51
-
-
0018090354
-
Insulin receptors are widely distributed in central nervous-system of rat
-
Havrankova J., and Roth J. Insulin receptors are widely distributed in central nervous-system of rat. Nature 212 (1978) 827-829
-
(1978)
Nature
, vol.212
, pp. 827-829
-
-
Havrankova, J.1
Roth, J.2
-
54
-
-
0020962084
-
Structural differences between insulin receptors in the brain and peripheral target tissues
-
Heidenreich K.A., Zahniser N.R., Berhanu P., Brandenburg D., and Olefsky J.M. Structural differences between insulin receptors in the brain and peripheral target tissues. J. Biol. Chem. 258 (1983) 8527-8530
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 8527-8530
-
-
Heidenreich, K.A.1
Zahniser, N.R.2
Berhanu, P.3
Brandenburg, D.4
Olefsky, J.M.5
-
55
-
-
0142137125
-
Upstream AUGs in embryonic proinsulin mRNA control its low translation level
-
Hernandez-Sanchez C., Mansilla A., de la Rosa E.J., Pollerberg G.E., Martinez-Salas E., and de Pablo F. Upstream AUGs in embryonic proinsulin mRNA control its low translation level. EMBO J. 22 (2003) 5582-5592
-
(2003)
EMBO J.
, vol.22
, pp. 5582-5592
-
-
Hernandez-Sanchez, C.1
Mansilla, A.2
de la Rosa, E.J.3
Pollerberg, G.E.4
Martinez-Salas, E.5
de Pablo, F.6
-
56
-
-
0036313627
-
Unprocessed proinsulin promotes cell survival during neurulation in the chick embryo
-
Hernandez-Sanchez C., Rubio E., Serna J., de la Rosa E.J., and de Pablo F. Unprocessed proinsulin promotes cell survival during neurulation in the chick embryo. Diabetes 51 (2002) 770-777
-
(2002)
Diabetes
, vol.51
, pp. 770-777
-
-
Hernandez-Sanchez, C.1
Rubio, E.2
Serna, J.3
de la Rosa, E.J.4
de Pablo, F.5
-
57
-
-
30444442827
-
Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain
-
Hoekman M.F., Jacobs F.M., Smidt M.P., and Burbach J.P. Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Exp. Patterns 6 (2006) 134-140
-
(2006)
Gene Exp. Patterns
, vol.6
, pp. 134-140
-
-
Hoekman, M.F.1
Jacobs, F.M.2
Smidt, M.P.3
Burbach, J.P.4
-
58
-
-
0037895042
-
Region-specific mRNA expression of phosphatidylinositol 3-kinase regulatory isoforms in the central nervous system of C57BL/6J mice
-
Horsch D., and Kahn C.R. Region-specific mRNA expression of phosphatidylinositol 3-kinase regulatory isoforms in the central nervous system of C57BL/6J mice. J. Comp. Neurol. 415 (1999) 105-120
-
(1999)
J. Comp. Neurol.
, vol.415
, pp. 105-120
-
-
Horsch, D.1
Kahn, C.R.2
-
59
-
-
1542267804
-
Disruption of forkhead transcription factor (FoxO) family members in mice reveals their functional diversification
-
Hosaka T., Biggs III W.H., Tieu D., Boyer A.D., Varki N.M., Cavenee W.K., and Arden K.C. Disruption of forkhead transcription factor (FoxO) family members in mice reveals their functional diversification. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 2975-2980
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 2975-2980
-
-
Hosaka, T.1
Biggs III, W.H.2
Tieu, D.3
Boyer, A.D.4
Varki, N.M.5
Cavenee, W.K.6
Arden, K.C.7
-
60
-
-
3242724040
-
Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression
-
Hou L., and Klann E. Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression. J. Neurosci. 24 (2004) 6352-6361
-
(2004)
J. Neurosci.
, vol.24
, pp. 6352-6361
-
-
Hou, L.1
Klann, E.2
-
61
-
-
0031928535
-
Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis
-
Hoyer S. Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis. J. Neural Transm. 105 (1998) 415-422
-
(1998)
J. Neural Transm.
, vol.105
, pp. 415-422
-
-
Hoyer, S.1
-
62
-
-
0029799241
-
Bidirectional regulation of protein kinase M zeta in the maintenance of long-term potentiation and long-term depression
-
Hrabetova S., and Sacktor T.C. Bidirectional regulation of protein kinase M zeta in the maintenance of long-term potentiation and long-term depression. J. Neurosci. 16 (1996) 5324-5333
-
(1996)
J. Neurosci.
, vol.16
, pp. 5324-5333
-
-
Hrabetova, S.1
Sacktor, T.C.2
-
63
-
-
0035500960
-
Transient translocation of conventional protein kinase C isoforms and persistent downregulation of atypical protein kinase Mzeta in long-term depression
-
Hrabetova S., and Sacktor T.C. Transient translocation of conventional protein kinase C isoforms and persistent downregulation of atypical protein kinase Mzeta in long-term depression. Brain Res. Mol. Brain Res. 95 (2001) 146-152
-
(2001)
Brain Res. Mol. Brain Res.
, vol.95
, pp. 146-152
-
-
Hrabetova, S.1
Sacktor, T.C.2
-
64
-
-
1842562359
-
An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampus
-
Huang C.C., Lee C.C., and Hsu K.S. An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampus. J. Neurochem. 89 (2004) 217-231
-
(2004)
J. Neurochem.
, vol.89
, pp. 217-231
-
-
Huang, C.C.1
Lee, C.C.2
Hsu, K.S.3
-
65
-
-
0028873368
-
Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy
-
Ishii D.N. Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy. Brain Res. Brain Res. Rev. 20 (1995) 47-67
-
(1995)
Brain Res. Brain Res. Rev.
, vol.20
, pp. 47-67
-
-
Ishii, D.N.1
-
66
-
-
0141481091
-
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics
-
Jacobs F.M., van der Heide L.P., Wijchers P.J., Burbach J.P., Hoekman M.F., and Smidt M.P. FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics. J. Biol. Chem. 278 (2003) 35959-35967
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35959-35967
-
-
Jacobs, F.M.1
van der Heide, L.P.2
Wijchers, P.J.3
Burbach, J.P.4
Hoekman, M.F.5
Smidt, M.P.6
-
67
-
-
0029081345
-
Glucose intolerance, hyperinsulinaemia and cognitive function in a general population of elderly men
-
Kalmijn S., Feskens E.J., Launer L.J., Stijnen T., and Kromhout D. Glucose intolerance, hyperinsulinaemia and cognitive function in a general population of elderly men. Diabetologia 38 (1995) 1096-1102
-
(1995)
Diabetologia
, vol.38
, pp. 1096-1102
-
-
Kalmijn, S.1
Feskens, E.J.2
Launer, L.J.3
Stijnen, T.4
Kromhout, D.5
-
68
-
-
0036325163
-
Decreased Akt activity is associated with activation of forkhead transcription factor after transient forebrain ischemia in gerbil hippocampus
-
Kawano T., Morioka M., Yano S., Hamada J., Ushio Y., Miyamoto E., and Fukunaga K. Decreased Akt activity is associated with activation of forkhead transcription factor after transient forebrain ischemia in gerbil hippocampus. J. Cereb. Blood Flow Metab. 22 (2002) 926-934
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 926-934
-
-
Kawano, T.1
Morioka, M.2
Yano, S.3
Hamada, J.4
Ushio, Y.5
Miyamoto, E.6
Fukunaga, K.7
-
69
-
-
0032714367
-
Deficits in nerve growth factor release and tyrosine receptor kinase phosphorylation are associated with age-related impairment in long-term potentiation in the dentate gyrus
-
Kelly A., Maguire C., and Lynch M.A. Deficits in nerve growth factor release and tyrosine receptor kinase phosphorylation are associated with age-related impairment in long-term potentiation in the dentate gyrus. Neuroscience 95 (2000) 359-365
-
(2000)
Neuroscience
, vol.95
, pp. 359-365
-
-
Kelly, A.1
Maguire, C.2
Lynch, M.A.3
-
70
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C., Chang J., Gensch E., Rudner A., and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 366 (1993) 461-464
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
71
-
-
0033014163
-
Central nervous system effects of intranasally administered insulin during euglycemia in men
-
Kern W., Born J., Schreiber H., and Fehm H.L. Central nervous system effects of intranasally administered insulin during euglycemia in men. Diabetes 48 (1999) 557-563
-
(1999)
Diabetes
, vol.48
, pp. 557-563
-
-
Kern, W.1
Born, J.2
Schreiber, H.3
Fehm, H.L.4
-
72
-
-
0030813398
-
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura K.D., Tissenbaum H.A., Liu Y., and Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277 (1997) 942-946
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
73
-
-
0021111565
-
A high molecular weight metalloendoprotease from the cytosol of mammalian cells
-
Kirschner R.J., and Goldberg A.L. A high molecular weight metalloendoprotease from the cytosol of mammalian cells. J. Biol. Chem. 258 (1983) 967-976
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 967-976
-
-
Kirschner, R.J.1
Goldberg, A.L.2
-
74
-
-
0036082509
-
Dynamic regulation of GABA(A) receptors at synaptic sites
-
Kneussel M. Dynamic regulation of GABA(A) receptors at synaptic sites. Brain Res. Brain Res. Rev. 39 (2002) 74-83
-
(2002)
Brain Res. Brain Res. Rev.
, vol.39
, pp. 74-83
-
-
Kneussel, M.1
-
75
-
-
0034845958
-
PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?
-
Lawlor M.A., and Alessi D.R. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?. J. Cell. Sci. 114 (2001) 2903-2910
-
(2001)
J. Cell. Sci.
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
76
-
-
24044474689
-
Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway
-
Lee C.C., Huang C.C., Wu M.Y., and Hsu K.S. Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway. J. Biol. Chem. 280 (2005) 18543-18550
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18543-18550
-
-
Lee, C.C.1
Huang, C.C.2
Wu, M.Y.3
Hsu, K.S.4
-
77
-
-
0031050268
-
Risk of dementia among persons with diabetes mellitus: a population-based cohort study
-
Leibson C.L., Rocca W.A., Hanson V.A., Cha R., Kokmen E., Obrien P.C., and Palumbo P.J. Risk of dementia among persons with diabetes mellitus: a population-based cohort study. Am. J. Epidemiol. 145 (1997) 301-308
-
(1997)
Am. J. Epidemiol.
, vol.145
, pp. 301-308
-
-
Leibson, C.L.1
Rocca, W.A.2
Hanson, V.A.3
Cha, R.4
Kokmen, E.5
Obrien, P.C.6
Palumbo, P.J.7
-
78
-
-
0346101885
-
Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death
-
Leissring M.A., Farris W., Chang A.Y., Walsh D.M., Wu X., Sun X., Frosch M.P., and Selkoe D.J. Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron 40 (2003) 1087-1093
-
(2003)
Neuron
, vol.40
, pp. 1087-1093
-
-
Leissring, M.A.1
Farris, W.2
Chang, A.Y.3
Walsh, D.M.4
Wu, X.5
Sun, X.6
Frosch, M.P.7
Selkoe, D.J.8
-
79
-
-
0032871462
-
Insulin modulation of cloned mouse NMDA receptor currents in Xenopus oocytes
-
Liao G.Y., and Leonard J.P. Insulin modulation of cloned mouse NMDA receptor currents in Xenopus oocytes. J. Neurochem. 73 (1999) 1510-1519
-
(1999)
J. Neurochem.
, vol.73
, pp. 1510-1519
-
-
Liao, G.Y.1
Leonard, J.P.2
-
80
-
-
0035855710
-
A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala
-
Lin C.H., Yeh S.H., Lin C.H., Lu K.T., Leu T.H., Chang W.C., and Gean P.W. A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala. Neuron 31 (2001) 841-851
-
(2001)
Neuron
, vol.31
, pp. 841-851
-
-
Lin, C.H.1
Yeh, S.H.2
Lin, C.H.3
Lu, K.T.4
Leu, T.H.5
Chang, W.C.6
Gean, P.W.7
-
81
-
-
0029000105
-
Insulin potentiates N-methyl-d-aspartate receptor activity in Xenopus oocytes and rat hippocampus
-
Liu L., Brown III J.C., Webster W.W., Morrisett R.A., and Monaghan D.T. Insulin potentiates N-methyl-d-aspartate receptor activity in Xenopus oocytes and rat hippocampus. Neurosci. Lett. 192 (1995) 5-8
-
(1995)
Neurosci. Lett.
, vol.192
, pp. 5-8
-
-
Liu, L.1
Brown III, J.C.2
Webster, W.W.3
Morrisett, R.A.4
Monaghan, D.T.5
-
82
-
-
0035957949
-
Insulin stimulates PKCzeta-mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins
-
Liu Y.F., Paz K., Herschkovitz A., Alt A., Tennenbaum T., Sampson S.R., Ohba M., Kuroki T., LeRoith D., and Zick Y. Insulin stimulates PKCzeta-mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins. J. Biol. Chem. 276 (2001) 14459-14465
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14459-14465
-
-
Liu, Y.F.1
Paz, K.2
Herschkovitz, A.3
Alt, A.4
Tennenbaum, T.5
Sampson, S.R.6
Ohba, M.7
Kuroki, T.8
LeRoith, D.9
Zick, Y.10
-
84
-
-
0242330837
-
Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats
-
Lupien S.B., Bluhm E.J., and Ishii D.N. Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats. J. Neurosci. Res. 74 (2003) 512-523
-
(2003)
J. Neurosci. Res.
, vol.74
, pp. 512-523
-
-
Lupien, S.B.1
Bluhm, E.J.2
Ishii, D.N.3
-
85
-
-
33748322197
-
-
Lupien, S.B., Bluhm, E.J., Ishii, D.N., 2005. Effect of IGF-I on DNA, RNA, and protein loss associated with brain atrophy and impaired learning in diabetic rats. Neurobiol Dis.
-
-
-
-
86
-
-
0346461652
-
Synaptic plasticity and AMPA receptor trafficking
-
Malenka R.C. Synaptic plasticity and AMPA receptor trafficking. Ann. NY Acad. Sci. 1003 (2005) 1-11
-
(2005)
Ann. NY Acad. Sci.
, vol.1003
, pp. 1-11
-
-
Malenka, R.C.1
-
87
-
-
0242363254
-
The long-term potential of LTP
-
Malenka R.C. The long-term potential of LTP. Nat. Rev. Neurosci. 4 (2003) 923-926
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 923-926
-
-
Malenka, R.C.1
-
88
-
-
0033793777
-
Intracellular trafficking of AMPA receptors in synaptic plasticity
-
Man H.Y., Ju W., Ahmadian G., and Wang Y.T. Intracellular trafficking of AMPA receptors in synaptic plasticity. Cell. Mol. Life Sci. 57 (2000) 1526-1534
-
(2000)
Cell. Mol. Life Sci.
, vol.57
, pp. 1526-1534
-
-
Man, H.Y.1
Ju, W.2
Ahmadian, G.3
Wang, Y.T.4
-
89
-
-
0033681557
-
Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
-
Man H.Y., Lin J.W., Ju W.H., Ahmadian G., Liu L., Becker L.E., Sheng M., and Wang Y.T. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron 25 (2000) 649-662
-
(2000)
Neuron
, vol.25
, pp. 649-662
-
-
Man, H.Y.1
Lin, J.W.2
Ju, W.H.3
Ahmadian, G.4
Liu, L.5
Becker, L.E.6
Sheng, M.7
Wang, Y.T.8
-
90
-
-
0037762556
-
Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons
-
Man H.Y., Wang Q., Lu W.Y., Ju W., Ahmadian G., Liu L., D'Souza S., Wong T.P., Taghibiglou C., Lu J., Becker L.E., Pei L., Liu F., Wymann M.P., MacDonald J.F., and Wang Y.T. Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons. Neuron 38 (2003) 611-624
-
(2003)
Neuron
, vol.38
, pp. 611-624
-
-
Man, H.Y.1
Wang, Q.2
Lu, W.Y.3
Ju, W.4
Ahmadian, G.5
Liu, L.6
D'Souza, S.7
Wong, T.P.8
Taghibiglou, C.9
Lu, J.10
Becker, L.E.11
Pei, L.12
Liu, F.13
Wymann, M.P.14
MacDonald, J.F.15
Wang, Y.T.16
-
91
-
-
28544450974
-
Developmental regulation of a proinsulin messenger RNA generated by intron retention
-
Mansilla A., Lopez-Sanchez C., de la Rosa E.J., Garcia-Martinez V., Martinez-Salas E., de Pablo F., and Hernandez-Sanchez C. Developmental regulation of a proinsulin messenger RNA generated by intron retention. EMBO Rep. 6 (2005) 1182-1187
-
(2005)
EMBO Rep.
, vol.6
, pp. 1182-1187
-
-
Mansilla, A.1
Lopez-Sanchez, C.2
de la Rosa, E.J.3
Garcia-Martinez, V.4
Martinez-Salas, E.5
de Pablo, F.6
Hernandez-Sanchez, C.7
-
92
-
-
3042700000
-
Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: from genes to phenotype
-
Marini A.M., Jiang X., Wu X., Tian F., Zhu D., Okagaki P., and Lipsky R.H. Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: from genes to phenotype. Restor. Neurol. Neurosci. 22 (2004) 121-130
-
(2004)
Restor. Neurol. Neurosci.
, vol.22
, pp. 121-130
-
-
Marini, A.M.1
Jiang, X.2
Wu, X.3
Tian, F.4
Zhu, D.5
Okagaki, P.6
Lipsky, R.H.7
-
93
-
-
0037471205
-
Early intracellular events induced by in vivo leptin treatment in mouse skeletal muscle
-
Maroni P., Bendinelli P., and Piccoletti R. Early intracellular events induced by in vivo leptin treatment in mouse skeletal muscle. Mol. Cell. Endocrinol. 201 (2003) 109-121
-
(2003)
Mol. Cell. Endocrinol.
, vol.201
, pp. 109-121
-
-
Maroni, P.1
Bendinelli, P.2
Piccoletti, R.3
-
94
-
-
0032742675
-
Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons
-
Matsuzaki H., Tamatani M., Mitsuda N., Namikawa K., Kiyama H., Miyake S., and Tohyama M. Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons. J. Neurochem. 73 (1999) 2037-2046
-
(1999)
J. Neurochem.
, vol.73
, pp. 2037-2046
-
-
Matsuzaki, H.1
Tamatani, M.2
Mitsuda, N.3
Namikawa, K.4
Kiyama, H.5
Miyake, S.6
Tohyama, M.7
-
95
-
-
0031044352
-
Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme
-
McDermott J.R., and Gibson A.M. Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme. Neurochem. Res. 22 (1997) 49-56
-
(1997)
Neurochem. Res.
, vol.22
, pp. 49-56
-
-
McDermott, J.R.1
Gibson, A.M.2
-
96
-
-
0022344785
-
Insulin, insulin-like growth factor II, and nerve growth factor effects on tubulin mRNA levels and neurite formation
-
Mill J.F., Chao M.V., and Ishii D.N. Insulin, insulin-like growth factor II, and nerve growth factor effects on tubulin mRNA levels and neurite formation. Proc. Natl. Acad. Sci. U.S.A. 82 (1985) 7126-7130
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 7126-7130
-
-
Mill, J.F.1
Chao, M.V.2
Ishii, D.N.3
-
97
-
-
0024595382
-
Degradation of insulin and insulin-like growth factors by enzyme purified from human erythrocytes. Comparison of degradation products observed with A14- and B26-[125I]monoiodoinsulin
-
Misbin R.I., and Almira E.C. Degradation of insulin and insulin-like growth factors by enzyme purified from human erythrocytes. Comparison of degradation products observed with A14- and B26-[125I]monoiodoinsulin. Diabetes 38 (1989) 152-158
-
(1989)
Diabetes
, vol.38
, pp. 152-158
-
-
Misbin, R.I.1
Almira, E.C.2
-
98
-
-
0037163050
-
Regulation of Raf-Akt Cross-talk
-
Moelling K., Schad K., Bosse M., Zimmermann S., and Schweneker M. Regulation of Raf-Akt Cross-talk. J. Biol. Chem. 277 (2002) 31099-31106
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31099-31106
-
-
Moelling, K.1
Schad, K.2
Bosse, M.3
Zimmermann, S.4
Schweneker, M.5
-
99
-
-
0030843594
-
Role of prepancreatic (pro)insulin and the insulin receptor in prevention of embryonic apoptosis
-
Morales A.V., Serna J., Alarcon C., de la Rosa E.J., and de Pablo F. Role of prepancreatic (pro)insulin and the insulin receptor in prevention of embryonic apoptosis. Endocrinology 138 (1997) 3967-3975
-
(1997)
Endocrinology
, vol.138
, pp. 3967-3975
-
-
Morales, A.V.1
Serna, J.2
Alarcon, C.3
de la Rosa, E.J.4
de Pablo, F.5
-
100
-
-
0034175485
-
Synaptic activity modulates the induction of bidirectional synaptic changes in adult mouse hippocampus
-
Ngezahayo A., Schachner M., and Artola A. Synaptic activity modulates the induction of bidirectional synaptic changes in adult mouse hippocampus. J. Neurosci. 20 (2000) 2451-2458
-
(2000)
J. Neurosci.
, vol.20
, pp. 2451-2458
-
-
Ngezahayo, A.1
Schachner, M.2
Artola, A.3
-
101
-
-
0037288941
-
Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities
-
Niswender K.D., and Schwartz M.W. Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Front. Neuroendocrinol. 24 (2003) 1-10
-
(2003)
Front. Neuroendocrinol.
, vol.24
, pp. 1-10
-
-
Niswender, K.D.1
Schwartz, M.W.2
-
102
-
-
0030659557
-
The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
Ogg S., Paradis S., Gottlieb S., Patterson G.I., Lee L., Tissenbaum H.A., and Ruvkun G. The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389 (1997) 994-999
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
Ruvkun, G.7
-
104
-
-
0029966901
-
Association of diabetes mellitus and dementia: The Rotterdam study
-
Ott A., Stolk R.P., Hofman A., van Harskamp F., Grobbee D.E., and Breteler M.M.B. Association of diabetes mellitus and dementia: The Rotterdam study. Diabetologia 39 (1996) 1392-1397
-
(1996)
Diabetologia
, vol.39
, pp. 1392-1397
-
-
Ott, A.1
Stolk, R.P.2
Hofman, A.3
van Harskamp, F.4
Grobbee, D.E.5
Breteler, M.M.B.6
-
105
-
-
0032764016
-
Diabetes mellitus and the risk of dementia-The Rotterdam Study
-
Ott A., Stolk R.P., van Harskamp F., Pols H.A.P., Hofman A., and Breteler M.M.B. Diabetes mellitus and the risk of dementia-The Rotterdam Study. Neurology 53 (1999) 1937-1942
-
(1999)
Neurology
, vol.53
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
van Harskamp, F.3
Pols, H.A.P.4
Hofman, A.5
Breteler, M.M.B.6
-
106
-
-
0034869177
-
Subunit-specific temporal and spatial patterns of AMP A receptor exocytosis in hippocampal neurons
-
Passafaro M., Piech V., and Sheng M. Subunit-specific temporal and spatial patterns of AMP A receptor exocytosis in hippocampal neurons. Nat. Neurosci. 4 (2001) 917-926
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 917-926
-
-
Passafaro, M.1
Piech, V.2
Sheng, M.3
-
107
-
-
0028034482
-
Developmentally regulated expression of the preproinsulin gene in the chicken embryo during gastrulation and neurulation
-
Perez-Villamil B., de la Rosa E.J., Morales A.V., and de Pablo F. Developmentally regulated expression of the preproinsulin gene in the chicken embryo during gastrulation and neurulation. Endocrinology 135 (1994) 2342-2350
-
(1994)
Endocrinology
, vol.135
, pp. 2342-2350
-
-
Perez-Villamil, B.1
de la Rosa, E.J.2
Morales, A.V.3
de Pablo, F.4
-
108
-
-
0346059592
-
MKP-1-induced dephosphorylation of extracellular signal-regulated kinase is essential for triggering nitric oxide-induced apoptosis in human breast cancer cell lines: implications in breast cancer
-
Pervin S., Singh R., Freije W.A., and Chaudhuri G. MKP-1-induced dephosphorylation of extracellular signal-regulated kinase is essential for triggering nitric oxide-induced apoptosis in human breast cancer cell lines: implications in breast cancer. Cancer Res. 63 (2003) 8853-8860
-
(2003)
Cancer Res.
, vol.63
, pp. 8853-8860
-
-
Pervin, S.1
Singh, R.2
Freije, W.A.3
Chaudhuri, G.4
-
109
-
-
0030694175
-
Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons
-
Philpott K.L., McCarthy M.J., Klippel A., and Rubin L.L. Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons. J. Cell. Biol. 139 (1997) 809-815
-
(1997)
J. Cell. Biol.
, vol.139
, pp. 809-815
-
-
Philpott, K.L.1
McCarthy, M.J.2
Klippel, A.3
Rubin, L.L.4
-
110
-
-
0017708427
-
Diabetes mellitus and its degenerative complications-prospective-study of 4400 patients observed between 1947 and 1973
-
Pirart J. Diabetes mellitus and its degenerative complications-prospective-study of 4400 patients observed between 1947 and 1973. Diab. Metab. 3 (1977) 245-256
-
(1977)
Diab. Metab.
, vol.3
, pp. 245-256
-
-
Pirart, J.1
-
111
-
-
0038362751
-
Akt activation promotes degradation of tuberin and FoxO3a via the proteasome
-
Plas D.R., and Thompson C.B. Akt activation promotes degradation of tuberin and FoxO3a via the proteasome. J. Biol. Chem. 278 (2003) 12361-12366
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12361-12366
-
-
Plas, D.R.1
Thompson, C.B.2
-
113
-
-
29844432266
-
Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis
-
Qiu W.Q., and Folstein M.F. Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis. Neurobiol. Aging 27 (2006) 190-198
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 190-198
-
-
Qiu, W.Q.1
Folstein, M.F.2
-
114
-
-
0000398342
-
Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation
-
Qiu W.Q., Walsh D.M., Ye Z., Vekrellis K., Zhang J., Podlisny M.B., Rosner M.R., Safavi A., Hersh L.B., and Selkoe D.J. Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation. J. Biol. Chem. 273 (1998) 32730-32738
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32730-32738
-
-
Qiu, W.Q.1
Walsh, D.M.2
Ye, Z.3
Vekrellis, K.4
Zhang, J.5
Podlisny, M.B.6
Rosner, M.R.7
Safavi, A.8
Hersh, L.B.9
Selkoe, D.J.10
-
115
-
-
0035986856
-
Functions of PI 3-kinase in development of the nervous system
-
Rodgers E.E., and Theibert A.B. Functions of PI 3-kinase in development of the nervous system. Int. J. Dev. Neurosci. 20 (2002) 187-197
-
(2002)
Int. J. Dev. Neurosci.
, vol.20
, pp. 187-197
-
-
Rodgers, E.E.1
Theibert, A.B.2
-
116
-
-
0033607784
-
Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt
-
Rommel C., Clarke B.A., Zimmermann S., Nunez L., Rossman R., Reid K., Moelling K., Yancopoulos G.D., and Glass D.J. Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science 286 (1999) 1738-1741
-
(1999)
Science
, vol.286
, pp. 1738-1741
-
-
Rommel, C.1
Clarke, B.A.2
Zimmermann, S.3
Nunez, L.4
Rossman, R.5
Reid, K.6
Moelling, K.7
Yancopoulos, G.D.8
Glass, D.J.9
-
117
-
-
0242353156
-
PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis
-
Rong R., Ahn J.Y., Huang H., Nagata E., Kalman D., Kapp J.A., Tu J., Worley P.F., Snyder S.H., and Ye K. PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis. Nat. Neurosci. 6 (2003) 1153-1161
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 1153-1161
-
-
Rong, R.1
Ahn, J.Y.2
Huang, H.3
Nagata, E.4
Kalman, D.5
Kapp, J.A.6
Tu, J.7
Worley, P.F.8
Snyder, S.H.9
Ye, K.10
-
118
-
-
0006460824
-
Phosphatidylinositol 3-kinase-mediated regulation of neuronal apoptosis and necrosis by insulin and IGF-I
-
Ryu B.R., Ko H.W., Jou I., Noh J.S., and Gwag B.J. Phosphatidylinositol 3-kinase-mediated regulation of neuronal apoptosis and necrosis by insulin and IGF-I. J. Neurobiol. 39 (1999) 536-546
-
(1999)
J. Neurobiol.
, vol.39
, pp. 536-546
-
-
Ryu, B.R.1
Ko, H.W.2
Jou, I.3
Noh, J.S.4
Gwag, B.J.5
-
119
-
-
0029843563
-
Identification of gamma-endorphin-generating enzyme as insulin-degrading enzyme
-
Safavi A., Miller B.C., Cottam L., and Hersh L.B. Identification of gamma-endorphin-generating enzyme as insulin-degrading enzyme. Biochemistry 35 (1996) 14318-14325
-
(1996)
Biochemistry
, vol.35
, pp. 14318-14325
-
-
Safavi, A.1
Miller, B.C.2
Cottam, L.3
Hersh, L.B.4
-
120
-
-
0036580702
-
Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region
-
Sanna P.P., Cammalleri M., Berton F., Simpson C., Lutjens R., Bloom F.E., and Francesconi W. Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region. J. Neurosci. 22 (2002) 3359-3365
-
(2002)
J. Neurosci.
, vol.22
, pp. 3359-3365
-
-
Sanna, P.P.1
Cammalleri, M.2
Berton, F.3
Simpson, C.4
Lutjens, R.5
Bloom, F.E.6
Francesconi, W.7
-
121
-
-
0026659501
-
Insulin-specific sensitization of cultured cerebrocortical neurons to glutamate excitotoxicity
-
Schafer M., and Erdo S.L. Insulin-specific sensitization of cultured cerebrocortical neurons to glutamate excitotoxicity. Brain Res. 580 (1992) 331-333
-
(1992)
Brain Res.
, vol.580
, pp. 331-333
-
-
Schafer, M.1
Erdo, S.L.2
-
122
-
-
0028179038
-
Immunohistochemical and in situ hybridization study of an insulin-like substance in fetal neuron cell cultures
-
Schechter R., Whitmire J., Wheet G.S., Beju D., Jackson K.W., Harlow R., and Gavin III J.R. Immunohistochemical and in situ hybridization study of an insulin-like substance in fetal neuron cell cultures. Brain Res. 636 (1994) 9-27
-
(1994)
Brain Res.
, vol.636
, pp. 9-27
-
-
Schechter, R.1
Whitmire, J.2
Wheet, G.S.3
Beju, D.4
Jackson, K.W.5
Harlow, R.6
Gavin III, J.R.7
-
123
-
-
0037862006
-
Unravelling the activation mechanisms of protein kinase B/Akt
-
Scheid M.P., and Woodgett J.R. Unravelling the activation mechanisms of protein kinase B/Akt. FEBS Lett. 546 (2003) 108-112
-
(2003)
FEBS Lett.
, vol.546
, pp. 108-112
-
-
Scheid, M.P.1
Woodgett, J.R.2
-
124
-
-
12144290448
-
Role for neuronal insulin resistance in neurodegenerative diseases
-
Schubert M., Gautam D., Surjo D., Ueki K., Baudler S., Schubert D., Kondo T., Alber J., Galldiks N., Kustermann E., Arndt S., Jacobs A.H., Krone W., Kahn C.R., and Bruning J.C. Role for neuronal insulin resistance in neurodegenerative diseases. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 3100-3105
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3100-3105
-
-
Schubert, M.1
Gautam, D.2
Surjo, D.3
Ueki, K.4
Baudler, S.5
Schubert, D.6
Kondo, T.7
Alber, J.8
Galldiks, N.9
Kustermann, E.10
Arndt, S.11
Jacobs, A.H.12
Krone, W.13
Kahn, C.R.14
Bruning, J.C.15
-
125
-
-
0026670206
-
Insulin in the brain: a hormonal regulator of energy balance
-
Schwartz M.W., Figlewicz D.P., Baskin D.G., Woods S.C., and Porte Jr. D. Insulin in the brain: a hormonal regulator of energy balance. Endocr. Rev. 13 (1992) 387-414
-
(1992)
Endocr. Rev.
, vol.13
, pp. 387-414
-
-
Schwartz, M.W.1
Figlewicz, D.P.2
Baskin, D.G.3
Woods, S.C.4
Porte Jr., D.5
-
126
-
-
0024573840
-
Insulin gene expression in chicken ontogeny: pancreatic, extrapancreatic, and prepancreatic
-
Serrano J., Bevins C.L., Young S.W., and de Pablo F. Insulin gene expression in chicken ontogeny: pancreatic, extrapancreatic, and prepancreatic. Dev. Biol. 132 (1989) 410-418
-
(1989)
Dev. Biol.
, vol.132
, pp. 410-418
-
-
Serrano, J.1
Bevins, C.L.2
Young, S.W.3
de Pablo, F.4
-
127
-
-
14244254168
-
Persistent phosphorylation by protein kinase Mzeta maintains late-phase long-term potentiation
-
Serrano P., Yao Y., and Sacktor T.C. Persistent phosphorylation by protein kinase Mzeta maintains late-phase long-term potentiation. J. Neurosci. 25 (2005) 1979-1984
-
(2005)
J. Neurosci.
, vol.25
, pp. 1979-1984
-
-
Serrano, P.1
Yao, Y.2
Sacktor, T.C.3
-
128
-
-
0035893251
-
Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity
-
Shanley L.J., Irving A.J., and Harvey J. Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity. J. Neurosci. 21 (2001) RC186
-
(2001)
J. Neurosci.
, vol.21
-
-
Shanley, L.J.1
Irving, A.J.2
Harvey, J.3
-
129
-
-
0035030492
-
The postsynaptic NMDA-receptor-PSD-95 signaling complex in excitatory synapses of the brain
-
Sheng M. The postsynaptic NMDA-receptor-PSD-95 signaling complex in excitatory synapses of the brain. J. Cell. Sci. 114 (2001) 1251
-
(2001)
J. Cell. Sci.
, vol.114
, pp. 1251
-
-
Sheng, M.1
-
130
-
-
7444265179
-
Brain insulin impairs amyloid-beta(1-40) clearance from the brain
-
Shiiki T., Ohtsuki S., Kurihara A., Naganuma H., Nishimura K., Tachikawa M., Hosoya K., and Terasaki T. Brain insulin impairs amyloid-beta(1-40) clearance from the brain. J. Neurosci. 24 (2004) 9632-9637
-
(2004)
J. Neurosci.
, vol.24
, pp. 9632-9637
-
-
Shiiki, T.1
Ohtsuki, S.2
Kurihara, A.3
Naganuma, H.4
Nishimura, K.5
Tachikawa, M.6
Hosoya, K.7
Terasaki, T.8
-
131
-
-
0032546462
-
Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain
-
Shin B.C., Suzuki M., Inukai K., Anai M., Asano T., and Takata K. Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain. Biochem. Biophys. Res. Commun. 246 (1998) 313-319
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.246
, pp. 313-319
-
-
Shin, B.C.1
Suzuki, M.2
Inukai, K.3
Anai, M.4
Asano, T.5
Takata, K.6
-
132
-
-
0037453461
-
Axons guided by insulin receptor in Drosophila visual system
-
Song J., Wu L., Chen Z., Kohanski R.A., and Pick L. Axons guided by insulin receptor in Drosophila visual system. Science 300 (2003) 502-505
-
(2003)
Science
, vol.300
, pp. 502-505
-
-
Song, J.1
Wu, L.2
Chen, Z.3
Kohanski, R.A.4
Pick, L.5
-
133
-
-
0029989471
-
LTD, LTP, and the sliding threshold for long-term synaptic plasticity
-
Stanton P.K. LTD, LTP, and the sliding threshold for long-term synaptic plasticity. Hippocampus 6 (1996) 35-42
-
(1996)
Hippocampus
, vol.6
, pp. 35-42
-
-
Stanton, P.K.1
-
134
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?
-
Steen E., Terry B.M., Rivera E.J., Cannon J.L., Neely T.R., Tavares R., Xu X.J., Wands J.R., and de la Monte S.M. Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?. J. Alzheimer's Dis. 7 (2005) 63-80
-
(2005)
J. Alzheimer's Dis.
, vol.7
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
Cannon, J.L.4
Neely, T.R.5
Tavares, R.6
Xu, X.J.7
Wands, J.R.8
de la Monte, S.M.9
-
135
-
-
0030997637
-
Insulin and cognitive function in an elderly population. The Rotterdam Study
-
Stolk R.P., Breteler M.M., Ott A., Pols H.A., Lamberts S.W., Grobbee D.E., and Hofman A. Insulin and cognitive function in an elderly population. The Rotterdam Study. Diab. Care 20 (1997) 792-795
-
(1997)
Diab. Care
, vol.20
, pp. 792-795
-
-
Stolk, R.P.1
Breteler, M.M.2
Ott, A.3
Pols, H.A.4
Lamberts, S.W.5
Grobbee, D.E.6
Hofman, A.7
-
136
-
-
0031014133
-
Diabetes mellitus, impaired glucose tolerance, and hyperinsulinemia in an elderly population. The Rotterdam Study
-
Stolk R.P., Pols H.A., Lamberts S.W., de Jong P.T., Hofman A., and Grobbee D.E. Diabetes mellitus, impaired glucose tolerance, and hyperinsulinemia in an elderly population. The Rotterdam Study. Am. J. Epidemiol. 145 (1997) 24-32
-
(1997)
Am. J. Epidemiol.
, vol.145
, pp. 24-32
-
-
Stolk, R.P.1
Pols, H.A.2
Lamberts, S.W.3
de Jong, P.T.4
Hofman, A.5
Grobbee, D.E.6
-
137
-
-
0036550053
-
3′-Phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling
-
Storz P., and Toker A. 3′-Phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling. Front. Biosci. 7 (2002) d886-d902
-
(2002)
Front. Biosci.
, vol.7
-
-
Storz, P.1
Toker, A.2
-
138
-
-
27844578300
-
Insulin and cognitive function in humans: experimental data and therapeutic considerations
-
Strachan M.W. Insulin and cognitive function in humans: experimental data and therapeutic considerations. Biochem. Soc. Trans. 33 (2005) 1037-1040
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 1037-1040
-
-
Strachan, M.W.1
-
139
-
-
15244340082
-
Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway
-
Subramaniam S., Shahani N., Strelau J., Laliberte C., Brandt R., Kaplan D., and Unsicker K. Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway. J. Neurosci. 25 (2005) 2838-2852
-
(2005)
J. Neurosci.
, vol.25
, pp. 2838-2852
-
-
Subramaniam, S.1
Shahani, N.2
Strelau, J.3
Laliberte, C.4
Brandt, R.5
Kaplan, D.6
Unsicker, K.7
-
140
-
-
0033753995
-
Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms
-
Sugimoto K., Murakawa Y., Zhang W., Xu G., and Sima A.A. Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms. Diab. Metab. Res. Rev. 16 (2000) 354-363
-
(2000)
Diab. Metab. Res. Rev.
, vol.16
, pp. 354-363
-
-
Sugimoto, K.1
Murakawa, Y.2
Zhang, W.3
Xu, G.4
Sima, A.A.5
-
141
-
-
0035166616
-
The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory
-
Sweatt J.D. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J. Neurochem. 76 (2001) 1-10
-
(2001)
J. Neurochem.
, vol.76
, pp. 1-10
-
-
Sweatt, J.D.1
-
142
-
-
2942550646
-
Mitogen-activated protein kinases in synaptic plasticity and memory
-
Sweatt J.D. Mitogen-activated protein kinases in synaptic plasticity and memory. Curr. Opin. Neurobiol. 14 (2004) 311-317
-
(2004)
Curr. Opin. Neurobiol.
, vol.14
, pp. 311-317
-
-
Sweatt, J.D.1
-
143
-
-
0032898857
-
The insulin signaling pathway
-
Taha C., and Klip A. The insulin signaling pathway. J. Membr. Biol. 169 (1999) 1-12
-
(1999)
J. Membr. Biol.
, vol.169
, pp. 1-12
-
-
Taha, C.1
Klip, A.2
-
144
-
-
0028820852
-
Insulin prevents apoptosis of external granular layer neurons in rat cerebellar slice cultures
-
Tanaka M., Sawada M., Yoshida S., Hanaoka F., and Marunouchi T. Insulin prevents apoptosis of external granular layer neurons in rat cerebellar slice cultures. Neurosci. Lett. 199 (1995) 37-40
-
(1995)
Neurosci. Lett.
, vol.199
, pp. 37-40
-
-
Tanaka, M.1
Sawada, M.2
Yoshida, S.3
Hanaoka, F.4
Marunouchi, T.5
-
145
-
-
0031935425
-
An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans
-
Tissenbaum H.A., and Ruvkun G. An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans. Genetics 148 (1998) 703-717
-
(1998)
Genetics
, vol.148
, pp. 703-717
-
-
Tissenbaum, H.A.1
Ruvkun, G.2
-
146
-
-
0034074486
-
Protein kinases as mediators of phosphoinositide 3-kinase signaling
-
Toker A. Protein kinases as mediators of phosphoinositide 3-kinase signaling. Mol. Pharmacol. 57 (2000) 652-658
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 652-658
-
-
Toker, A.1
-
147
-
-
0035086678
-
Phosphatidylinositol-3-OH kinase regulatory subunits are differentially expressed during development of the rat cerebellum
-
Trejo J.L., and Pons S. Phosphatidylinositol-3-OH kinase regulatory subunits are differentially expressed during development of the rat cerebellum. J. Neurobiol. 47 (2001) 39-50
-
(2001)
J. Neurobiol.
, vol.47
, pp. 39-50
-
-
Trejo, J.L.1
Pons, S.2
-
148
-
-
0344530503
-
Insulin inhibition of transcription stimulated by the forkhead protein Foxol is not solely due to nuclear exclusion
-
Tsai W.C., Bhattacharyya N., Han L.Y., Hanover J.A., and Rechler M.M. Insulin inhibition of transcription stimulated by the forkhead protein Foxol is not solely due to nuclear exclusion. Endocrinology 144 (2003) 5615-5622
-
(2003)
Endocrinology
, vol.144
, pp. 5615-5622
-
-
Tsai, W.C.1
Bhattacharyya, N.2
Han, L.Y.3
Hanover, J.A.4
Rechler, M.M.5
-
149
-
-
0031725083
-
Insulin receptors and signal transduction proteins in the hypothalamo-hypophyseal system: a review on morphological findings and functional implications
-
Unger J.W., and Betz M. Insulin receptors and signal transduction proteins in the hypothalamo-hypophyseal system: a review on morphological findings and functional implications. Histol. Histopathol. 13 (1998) 1215-1224
-
(1998)
Histol. Histopathol.
, vol.13
, pp. 1215-1224
-
-
Unger, J.W.1
Betz, M.2
-
150
-
-
1642580584
-
Group I metabotropic glutamate receptors regulate the frequency-response function of hippocampal CA1 synapses for the induction of LTP and LTD
-
van Dam E.J., Kamal A., Artola A., de Graan P.N., Gispen W.H., and Ramakers G.M. Group I metabotropic glutamate receptors regulate the frequency-response function of hippocampal CA1 synapses for the induction of LTP and LTD. Eur. J. Neurosci. 19 (2004) 112-118
-
(2004)
Eur. J. Neurosci.
, vol.19
, pp. 112-118
-
-
van Dam, E.J.1
Kamal, A.2
Artola, A.3
de Graan, P.N.4
Gispen, W.H.5
Ramakers, G.M.6
-
151
-
-
0037632930
-
Insulin inhibits extracellular regulated kinase 1/2 phosphorylation in a phosphatidylinositol 3-kinase (PI3) kinase-dependent manner in Neuro2a cells
-
van der Heide L.P., Hoekman M.F., Biessels G.J., and Gispen W.H. Insulin inhibits extracellular regulated kinase 1/2 phosphorylation in a phosphatidylinositol 3-kinase (PI3) kinase-dependent manner in Neuro2a cells. J. Neurochem. 86 (2003) 86-91
-
(2003)
J. Neurochem.
, vol.86
, pp. 86-91
-
-
van der Heide, L.P.1
Hoekman, M.F.2
Biessels, G.J.3
Gispen, W.H.4
-
152
-
-
2942726155
-
The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation
-
van der Heide L.P., Hoekman M.F., and Smidt M.P. The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation. Biochem. J. 380 (2004) 291-309
-
(2004)
Biochem. J.
, vol.380
, pp. 291-309
-
-
van der Heide, L.P.1
Hoekman, M.F.2
Smidt, M.P.3
-
153
-
-
27744432642
-
FoxO6 transcriptional activity is regulated by Thr26 and Serl84, independent of nucleo-cytoplasmic shuttling
-
van der Heide L.P., Jacobs F.M., Burbach J.P., Hoekman M.F., and Smidt M.P. FoxO6 transcriptional activity is regulated by Thr26 and Serl84, independent of nucleo-cytoplasmic shuttling. Biochem. J. 391 (2005) 623-629
-
(2005)
Biochem. J.
, vol.391
, pp. 623-629
-
-
van der Heide, L.P.1
Jacobs, F.M.2
Burbach, J.P.3
Hoekman, M.F.4
Smidt, M.P.5
-
154
-
-
23844470857
-
Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner
-
van der Heide L.P., Kamal A., Artola A., Gispen W.H., and Ramakers G.M. Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner. J. Neurochem. 94 (2005) 1158-1166
-
(2005)
J. Neurochem.
, vol.94
, pp. 1158-1166
-
-
van der Heide, L.P.1
Kamal, A.2
Artola, A.3
Gispen, W.H.4
Ramakers, G.M.5
-
155
-
-
0034653608
-
The PI3K-PDK1 connection: more than just a road to PKB
-
Vanhaesebroeck B., and Alessi D.R. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346 Pt 3 (2000) 561-576
-
(2000)
Biochem. J.
, vol.346
, Issue.PART 3
, pp. 561-576
-
-
Vanhaesebroeck, B.1
Alessi, D.R.2
-
156
-
-
0033604577
-
Signaling by distinct classes of phosphoinositide 3-kinases
-
Vanhaesebroeck B., and Waterfield M.D. Signaling by distinct classes of phosphoinositide 3-kinases. Exp. Cell. Res. 253 (1999) 239-254
-
(1999)
Exp. Cell. Res.
, vol.253
, pp. 239-254
-
-
Vanhaesebroeck, B.1
Waterfield, M.D.2
-
157
-
-
0030800192
-
Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin
-
Wan Q., Xiong Z.G., Man H.Y., Ackerley C.A., Braunton J., Lu W.Y., Becker L.E., MacDonald J.F., and Wang Y.T. Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin. Nature 388 (1997) 686-690
-
(1997)
Nature
, vol.388
, pp. 686-690
-
-
Wan, Q.1
Xiong, Z.G.2
Man, H.Y.3
Ackerley, C.A.4
Braunton, J.5
Lu, W.Y.6
Becker, L.E.7
MacDonald, J.F.8
Wang, Y.T.9
-
158
-
-
0026559410
-
Effects of insulin and insulin-like growth factors on neurofilament mRNA and tubulin mRNA content in human neuroblastoma SH-SY5Y cells
-
Wang C., Li Y., Wible B., Angelides K.J., and Ishii D.N. Effects of insulin and insulin-like growth factors on neurofilament mRNA and tubulin mRNA content in human neuroblastoma SH-SY5Y cells. Brain Res. Mol. Brain Res. 13 (1992) 289-300
-
(1992)
Brain Res. Mol. Brain Res.
, vol.13
, pp. 289-300
-
-
Wang, C.1
Li, Y.2
Wible, B.3
Angelides, K.J.4
Ishii, D.N.5
-
159
-
-
0028360327
-
Regulation of NMDA receptors by tyrosine kinases and phosphatases
-
Wang Y.T., and Salter M.W. Regulation of NMDA receptors by tyrosine kinases and phosphatases. Nature 369 (1994) 233-235
-
(1994)
Nature
, vol.369
, pp. 233-235
-
-
Wang, Y.T.1
Salter, M.W.2
-
160
-
-
0030748457
-
The insulin signalling system and the IRS proteins
-
White M.F. The insulin signalling system and the IRS proteins. Diabetologia 40 Suppl. 2 (1997) S2-S17
-
(1997)
Diabetologia
, vol.40
, Issue.SUPPL. 2
-
-
White, M.F.1
-
161
-
-
0031918624
-
The IRS-signalling system: a network of docking proteins that mediate insulin action
-
White M.F. The IRS-signalling system: a network of docking proteins that mediate insulin action. Mol. Cell. Biochem. 182 (1998) 3-11
-
(1998)
Mol. Cell. Biochem.
, vol.182
, pp. 3-11
-
-
White, M.F.1
-
162
-
-
0036710280
-
IRS proteins and the common path to diabetes
-
White M.F. IRS proteins and the common path to diabetes. Am. J. Physiol. Endocrinol. Metab. 283 (2002) E413-E422
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.283
-
-
White, M.F.1
-
163
-
-
0034893106
-
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome lq
-
Wiltshire S., Hattersley A.T., Hitman G.A., Walker M., Levy J.C., Sampson M., O'Rahilly S., Frayling T.M., Bell J.I., Lathrop G.M., Bennett A., Dhillon R., Fletcher C., Groves C.J., Jones E., Prestwich P., Simecek N., Rao P.V., Wishart M., Bottazzo G.F., Foxon R., Howell S., Smedley D., Cardon L.R., Menzel S., and McCarthy M.I. A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome lq. Am. J. Hum. Genet. 69 (2001) 553-569
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 553-569
-
-
Wiltshire, S.1
Hattersley, A.T.2
Hitman, G.A.3
Walker, M.4
Levy, J.C.5
Sampson, M.6
O'Rahilly, S.7
Frayling, T.M.8
Bell, J.I.9
Lathrop, G.M.10
Bennett, A.11
Dhillon, R.12
Fletcher, C.13
Groves, C.J.14
Jones, E.15
Prestwich, P.16
Simecek, N.17
Rao, P.V.18
Wishart, M.19
Bottazzo, G.F.20
Foxon, R.21
Howell, S.22
Smedley, D.23
Cardon, L.R.24
Menzel, S.25
McCarthy, M.I.26
more..
-
165
-
-
0027391758
-
The cellular and physiological actions of insulin in the central nervous system
-
Wozniak M., Rydzewski B., Baker S.P., and Raizada M.K. The cellular and physiological actions of insulin in the central nervous system. Neurochem. Int. 22 (1993) 1-10
-
(1993)
Neurochem. Int.
, vol.22
, pp. 1-10
-
-
Wozniak, M.1
Rydzewski, B.2
Baker, S.P.3
Raizada, M.K.4
-
166
-
-
4143136343
-
AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3-kinase-dependent activation in extracellular signal-regulated kinase to upregulate BDNF gene expression
-
Wu X., Zhu D., Jiang X., Okagaki P., Mearow K., Zhu G., McCall S., Banaudha K., Lipsky R.H., and Marini A.M. AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3-kinase-dependent activation in extracellular signal-regulated kinase to upregulate BDNF gene expression. J. Neurochem. 90 (2004) 807-818
-
(2004)
J. Neurochem.
, vol.90
, pp. 807-818
-
-
Wu, X.1
Zhu, D.2
Jiang, X.3
Okagaki, P.4
Mearow, K.5
Zhu, G.6
McCall, S.7
Banaudha, K.8
Lipsky, R.H.9
Marini, A.M.10
-
167
-
-
0038730942
-
Brain-derived neurotrophic factor/TrkB signaling in memory processes
-
Yamada K., and Nabeshima T. Brain-derived neurotrophic factor/TrkB signaling in memory processes. J. Pharmacol. Sci. 91 (2003) 267-270
-
(2003)
J. Pharmacol. Sci.
, vol.91
, pp. 267-270
-
-
Yamada, K.1
Nabeshima, T.2
-
168
-
-
0035895964
-
Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53
-
Yamaguchi A., Tamatani M., Matsuzaki H., Namikawa K., Kiyama H., Vitek M.P., Mitsuda N., and Tohyama M. Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. J. Biol. Chem. 276 (2001) 5256-5264
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5256-5264
-
-
Yamaguchi, A.1
Tamatani, M.2
Matsuzaki, H.3
Namikawa, K.4
Kiyama, H.5
Vitek, M.P.6
Mitsuda, N.7
Tohyama, M.8
-
169
-
-
10944228564
-
Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention
-
Zhao L., Teter B., Morihara T., Lim G.P., Ambegaokar S.S., Ubeda O.J., Frautschy S.A., and Cole G.M. Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention. J. Neurosci. 24 (2004) 11120-11126
-
(2004)
J. Neurosci.
, vol.24
, pp. 11120-11126
-
-
Zhao, L.1
Teter, B.2
Morihara, T.3
Lim, G.P.4
Ambegaokar, S.S.5
Ubeda, O.J.6
Frautschy, S.A.7
Cole, G.M.8
-
170
-
-
0033521130
-
Brain insulin receptors and spatial memory. correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats
-
Zhao W., Chen H., Xu H., Moore E., Meiri N., Quon M.J., and Alkon D.L. Brain insulin receptors and spatial memory. correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats. J. Biol. Chem. 274 (1999) 34893-34902
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34893-34902
-
-
Zhao, W.1
Chen, H.2
Xu, H.3
Moore, E.4
Meiri, N.5
Quon, M.J.6
Alkon, D.L.7
-
171
-
-
0036078618
-
Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons
-
Zheng W.H., Kar S., and Quirion R. Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons. Mol. Pharmacol. 62 (2002) 225-233
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 225-233
-
-
Zheng, W.H.1
Kar, S.2
Quirion, R.3
-
172
-
-
0036389374
-
Co-activation of the phosphatidylinositol-3-kinase/Akt signaling pathway by N-methyl-d-aspartate and TrkB receptors in cerebellar granule cell neurons
-
Zhu D., Lipsky R.H., and Marini A.M. Co-activation of the phosphatidylinositol-3-kinase/Akt signaling pathway by N-methyl-d-aspartate and TrkB receptors in cerebellar granule cell neurons. Amino Acids 23 (2002) 11-17
-
(2002)
Amino Acids
, vol.23
, pp. 11-17
-
-
Zhu, D.1
Lipsky, R.H.2
Marini, A.M.3
-
173
-
-
0033607633
-
Phosphorylation and regulation of Raf by Akt (protein kinase B)
-
Zimmermann S., and Moelling K. Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 286 (1999) 1741-1744
-
(1999)
Science
, vol.286
, pp. 1741-1744
-
-
Zimmermann, S.1
Moelling, K.2
|