Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase

Journal of Applied Physiology

Volumn 91, Issue 3, 2001, Pages 1073-1083

  Zheng, Donghai ^a   Maclean, Paul S ^a   Pohnert, Steven C ^a   Knight, John B ^b   Olson, Ann Louise ^b   Winder, William W ^c   Dohm, G Lynis ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

GLUT 4 promoter; Muscle fiber type; Myocyte enhancer factor 2; Transgenic mice

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; GLUCOSE TRANSPORTER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASE PAIRING; CONSENSUS SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; MALE; MOUSE; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; QUADRICEPS FEMORIS MUSCLE; RAT; SKELETAL MUSCLE; SOLEUS MUSCLE; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE;

EID: 0034863102     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2001.91.3.1073     Document Type: Article

References (52)

1. Chronic treatment with 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT-4 translocation in rat skeletal muscles in a fiber type-specific manner
2. Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism
3. Mutants of yeast defective in sucrose utilization
4. Effect of aging on response to exercise training in humans: Skeletal muscle GLUT-4 and insulin sensitivity
5. Role of glucose transport and GLUT-4 transporter protein in type 2 diabetes mellitus
6. Regulated nuclear translocation of the Mig1 glucose repressor
7. AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes
8. Exercise training increases glucose transporter protein GLUT-4 in skeletal muscle of obese Zucker (fa/fa) rats
9. Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT-4)
10. Glucose transporter number, function, and subcellular distribution in rat skeletal muscle after exercise training
11. Exercise, glucose transport, and insulin sensitivity
12. The AMP-activated protein kinase - Fuel gauge of the mammalian cell
13. Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase
14. Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
15. Exercise training increases GLUT-4 protein concentration in previously sedentary middle-aged men
16. Skeletal muscle GLUT-4 protein concentration and aging in humans
17. Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase
18. High fat diet-induced hyperglycemia: Prevention by low level expression of a glucose transporter (GLUT-4) minigene in transgenic mice
19. Regulation of glucose transporter GLUT-4 and hexokinase II gene transcription by insulin and epinephrine
20. Regulation of glucose transporters GLUT-4 and GLUT-1 gene transcription in denervated skeletal muscle
21. Dealing with energy demand: The AMP-activated protein kinase
22. 5′ AMP-activated protein kinase activation causes GLUT-4 translocation in skeletal muscle
23. The 5′-AMP-activated protein kinase inhibits the transcriptional stimulation by glucose in liver cells, acting through the glucose response complex
24. Improvement of insulin action in diabetic transgenic mice selectively overexpressing GLUT-4 in skeletal muscle
25. Expression and regulation of the human GLUT-4/muscle-fat facilitative glucose transporter gene in transgenic mice
26. 5-Aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase
27. AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle
28. Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae
29. Exercise induces a transient increase in transcription of the GLUT-4 gene in skeletal muscle
30. Effect of training and detraining on skeletal muscle glucose transporter (GLUT-4) content in rats
31. Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro
32. Transcriptional regulation of the human GLUT-4 gene promoter in diabetic transgenic mice
33. Identification of a 30-base pair regulatory element and novel DNA binding protein that regulates the human GLUT-4 promoter in transgenic mice
34. Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise
35. Adaptation of muscle to creatine depletion: Effect on GLUT-4 glucose transporter expression
36. Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
37. Metabolism of 5-amino-4-imidazolecarboxamide riboside in cardiac and skeletal muscle. Effects on purine nucleotide synthesis
38. AMP-activated protein kinase: Greater AMP dependence, and preferential nuclear localization, of complexes containing the α2 isoform
39. Mammalian AMP-activated protein kinase subfamily
40. GLUT-4 heterozygous knockout mice develop muscle insulin resistance and diabetes
41. Myocyte enhancer factor 2 (MEF-2)-binding site is required for GLUT-4 gene expression in transgenic mice. Regulation of MEF-2 DNA binding activity in insulin-deficient diabetes
42. Enhanced peripheral glucose utilization in transgenic mice expressing the human GLUT-4 gene
43. Regulated expression of 5′-deleted mouse GLUT-4 minigenes in transgenic mice: Effects of exercise training and high-fat diet
44. Localization of exercise- and denervation-responsive elements in the mouse GLUT-4 gene
45. Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle
46. The AMP-activated protein kinase gene is highly expressed in rat skeletal muscle. Alternative splicing and tissue distribution of the mRNA
47. Hypoglycaemic effect of AICA riboside in mice
48. Inhibition by AICA riboside of gluconeogenesis in isolated rat hepatocytes
49. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
50. AMP-activated protein kinase, a metabolic master switch: Possible roles in type 2 diabetes
51. Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
52. Searching for ways to upregulate GLUT-4 glucose transporter expression in muscle