The role of Fis1p-Mdv1p interactions in mitochondrial fission complex assembly

Journal of Cell Biology

Volumn 171, Issue 2, 2005, Pages 291-301

  Karren, Mary Anne ^a   Coonrod, Emily M ^a   Anderson, Teresa K ^a   Shaw, Janet M ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; PROTEIN; PROTEIN FIS1; PROTEIN MDV1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; MITOCHONDRION; MUTATION; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; TETRATRICOPEPTIDE REPEAT;

CARRIER PROTEINS; GTP PHOSPHOHYDROLASES; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TEMPERATURE;

EID: 27544450920     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200506158     Document Type: Article

References (58)

1. Arimura, S., and N. Tsutsumi. 2002. A dynamin-like protein (ADL2b), rather than FtsZ, is involved in Arabidopsis mitochondrial division. Proc. Natl. Acad. Sci. USA. 99:5727-5731.
2. Bevis, B.J., and B.S. Glick. 2002. Rapidly maturing variants of the Discosoma red fluorescent protein (DsRed). Nat. Biotechnol. 20:83-87.
3. Bleazard, W., J.M. McCaffery, E.J. King, S. Bale, A. Mozdy, Q. Tieu, J. Nunnari, and J.M. Shaw. 1999. The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat. Cell Biol. 1:298-304.
4. Boeke, J.D., J. Trueheart, G. Natsoulis, and G.R. Fink. 1987. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154:164-175.
5. Bossy-Wetzel, E., M.J. Barsoum, A. Godzik, R. Schwarzenbacher, and S.A. Lipton. 2003. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr. Opin. Cell Biol. 15:706-716.
6. Cerveny, K.L., and R.E. Jensen. 2003. The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondria. Mol. Biol. Cell. 14:4126-4139.
7. Cerveny, K.L., J.M. McCaffery, and R.E. Jensen. 2001. Division of mitochondria requires a novel DNM1-interacting protein, Net2p. Mol. Biol. Cell. 12:309-321.
8. Chen, H., and D.C. Chan. 2004. Mitochondrial dynamics in mammals. Curr. Top. Dev. Biol. 59:119-144.
9. D'Andrea, L.D., and L. Regan. 2003. TPR proteins: the versatile helix. Trends Biochem. Sci. 28:655-662.
10. Dohm, J.A., S.J. Lee, J.M. Hardwick, R.B. Hill, and A.G. Gittis. 2004. Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold. Proteins. 54:153-156.
11. Fekkes, P., K.A. Shepard, and M.P. Yaffe. 2000. Gag3p, an outer membrane protein required for fission of mitochondrial tubules. J. Cell Biol. 151:333-340.
12. Frank, S., B. Gaume, E.S. Bergmann-Leitner, W.W. Leitner, E.G. Robert, F. Catez, C.L. Smith, and R.J. Youle. 2001. The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev. Cell. 1:515-525.
13. Fukushima, N.H., E. Brisch, B.R. Keegan, W. Bleazard, and J.M. Shaw. 2001. The GTPase effector domain sequence of the Dnm1p GTPase regulates self-assembly and controls a rate-limiting step in mitochondrial fission. Mol. Biol. Cell. 12:2756-2766.
14. Griffin, E.E., J. Graumann, and D.C. Chan. 2005. The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria. J. Cell Biol. 170:237-248.
15. Guthrie, C., and G. Fink. 1991. Guide to yeast genetics and molecular biology. Methods in Enzymology. Vol. 194. San Diego: Academic Press, Inc.
16. Guthrie, C., and G. Fink. 2002. Guide to yeast genetics and molecular biology. Methods in Enzymology. Vol. 350. San Diego: Academic Press, Inc.
17. Hales, K.G., and M.T. Fuller. 1997. Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase. Cell 90:121-129.
18. Hermann, G.J., and J.M. Shaw. 1998. Mitochondrial dynamics in yeast. Annu. Rev. Cell Dev. Biol. 14:265-303.
19. Hermann, G.J., J.W. Thatcher, J.P. Mills, K.G. Hales, M.T. Fuller, J. Nunnari, and J.M. Shaw. 1998. Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J. Cell Biol. 143:359-373.
20. Holm, L., and C. Sander. 1993. Protein structure comparison by alignment of distance matrices. J. Mol. Biol. 233:123-138.
21. Jagasia, R., P. Grote, B. Westermann, and B. Conradt. 2005. DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans. Nature. 433:754-760.
22. James, D.I., P.A. Parone, Y. Mattenberger, and J.C. Martinou. 2003. hFis1, a novel component of the mammalian mitochondrial fission machinery. J. Biol. Chem. 278:36373-36379.
23. James, P., J. Halladay, and E.A. Craig. 1996. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics. 144:1425-1436.
24. Jensen, R.E., A.E. Hobbs, K.L. Cerveny, and H. Sesaki. 2000. Yeast mitochondrial dynamics: fusion, division, segregation, and shape. Microsc. Res. Tech. 51:573-583.
25. Karbowski, M., and R.J. Youle. 2003. Dynamics of mitochondrial morphology in healthy cells and during apoptosis. Cell Death Differ. 10:870-880.
26. Kondo-Okamoto, N., J.M. Shaw, and K. Okamoto. 2003. Mmm1p spans both the outer and inner mitochondrial membranes and contains distinct domains for targeting and foci formation. J. Biol. Chem. 278:48997-49005.
27. Labrousse, A.M., M.D. Zappaterra, D.A. Rube, and A.M. van der Bliek. 1999. C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane. Mol. Cell. 4:815-826.
28. Lee, Y.J., S.Y. Jeong, M. Karbowski, C.L. Smith, and R.J. Youle. 2004. Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol. Biol. Cell. 15:5001-5011.
29. Legesse-Miller, A., R.H. Massol, and T. Kirchhausen. 2003. Constriction and Dnm1p recruitment are distinct processes in mitochondrial fission. Mol. Biol. Cell. 14:1953-1963.
30. Li, Z., K. Okamoto, Y. Hayashi, and M. Sheng. 2004. The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell. 119:873-887.
31. Maniatis, T., E.F. Fritsch, and J. Sambrook. 1982. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 545 pp.
32. Mozdy, A.D., and J.M. Shaw. 2003. A fuzzy mitochondrial fusion apparatus comes into focus. Nat. Rev. Mol. Cell Biol. 4:468-478.
33. Mozdy, A.D., J.M. McCaffery, and J.M. Shaw. 2000. Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p. J. Cell Biol. 151:367-380.
34. Mumberg, D., R. Muller, and M. Funk. 1995. Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene. 156:119-122.
35. Okamoto, K., and J.M. Shaw. 2005. Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu. Rev. Genet. 39:503-536.
36. Orr-Weaver, T.L., J.W. Szostak, and R.J. Rothstein. 1983. Genetic applications of yeast transformation with linear and gapped plasmids. Methods Enzymol. 101:228-245.
37. Osteryoung, K.W., and J. Nunnari. 2003. The division of endosymbiotic organelles. Science. 302:1698-1704.
38. Otsuga, D., B.R. Keegan, E. Brisch, J.W. Thatcher, G.J. Hermann, W. Bleazard, and J.M. Shaw. 1998. The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeast. J. Cell Biol. 143:333-349.
39. Rapaport, D., M. Brunner, W. Neupert, and B. Westermann. 1998. Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae. J. Biol. Chem. 273:20150-20155.
40. Rothstein, R. 1991. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194:281-301.
41. 2+ signals, mitochondrial fission and sensitization to apoptosis. Cell Death Differ. 10:1287-1289.
42. Sesaki, H., and R.E. Jensen. 1999. Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape. J. Cell Biol. 147:699-706.
43. Shaw, J.M., and J. Nunnari. 2002. Mitochondrial dynamics and division in budding yeast. Trends Cell Biol. 12:178-184.
44. Sherman, F., G.R. Fink, and J.B. Hicks. 1986. Methods in Yeast Genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 186 pp.
45. Smirnova, E., D.L. Shurland, S.N. Ryazantsev, and A.M. van der Bliek. 1998. A human dynamin-related protein controls the distribution of mitochondria. J. Cell Biol. 143:351-358.
46. Stojanovski, D., O.S. Koutsopoulos, K. Okamoto, and M.T. Ryan. 2004. Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology. J. Cell Sci. 117:1201-1210.
47. Suzuki, M., S.Y. Jeong, M. Karbowski, R.J. Youle, and N. Tjandra. 2003. The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle. J. Mol. Biol. 334:445-458.
48. Suzuki, M., A. Neutzner, N. Tjandra, and R.J. Youle. 2005. Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission. J. Biol. Chem. 280:21444-21452.
49. 2+-mediated apoptosis. Mol. Cell. 16:59-68.
50. Tieu, Q., and J. Nunnari. 2000. Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division. J. Cell Biol. 151:353-366.
51. Tieu, Q., V. Okreglak, K. Naylor, and J. Nunnari. 2002. The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission. J. Cell Biol. 158:445-452.
52. van der Bliek, A.M. 2000. A mitochondrial division apparatus takes shape. J. Cell Biol. 151:F1-F4.
53. Westermann, B. 2002. Merging mitochondria matters: cellular role and molecular machinery of mitochondrial fusion. EMBO Rep. 3:527-531.
54. Westermann, B. 2003. Mitochondrial membrane fusion. Biochim. Biophys. Acta. 1641:195-202.
55. Westermann, B., and H. Prokisch. 2002. Mitochondrial dynamics in filamentous fungi. Fungal Genet. Biol. 36:91-97.
56. Winston, F., C. Dollard, and S.L. Ricupero-Hovasse. 1995. Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C. Yeast. 11:53-55.
57. Yaffe, M.P. 1999. The machinery of mitochondrial inheritance and behavior. Science. 283:1493-1497.
58. Yoon, Y., E.W. Krueger, B.J. Oswald, and M.A. McNiven. 2003. The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Mol. Cell. Biol. 23:5409-5420.