-
1
-
-
0036810352
-
Heat-shock protein 90, a chaperone for folding and regulation
-
Picard, D. (2002) Heat-shock protein 90, a chaperone for folding and regulation. Cell Mol. Life Sci.,59, 1640-1648.
-
(2002)
Cell Mol. Life Sci.
, vol.59
, pp. 1640-1648
-
-
Picard, D.1
-
2
-
-
0024421221
-
Hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures
-
Borkovich, K. A., Farrelly, F. W., Finkelstein, D. B., Taulien, J., and Lindquist, S. (1989) hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures. Mol. Cell Biol.,9, 3919-3930.
-
(1989)
Mol. Cell Biol.
, vol.9
, pp. 3919-3930
-
-
Borkovich, K.A.1
Farrelly, F.W.2
Finkelstein, D.B.3
Taulien, J.4
Lindquist, S.5
-
3
-
-
0024364170
-
Sequence and regulation of a gene encoding a human 89-kilodalton heat shock protein
-
Hickey, E., Brandon, S. E., Smale, G., Lloyd, D., and Weber, L. A. (1989) Sequence and regulation of a gene encoding a human 89-kilodalton heat shock protein. Mol. Cell Biol.,9, 2615-2626.
-
(1989)
Mol. Cell Biol.
, vol.9
, pp. 2615-2626
-
-
Hickey, E.1
Brandon, S.E.2
Smale, G.3
Lloyd, D.4
Weber, L.A.5
-
4
-
-
0034817255
-
The Hsp90 family of proteins in Arabidopsis thaliana
-
Krishna, P. and Gloor, G. (2001) The Hsp90 family of proteins in Arabidopsis thaliana. Cell Stress. Chaperones.,6, 238-246.
-
(2001)
Cell Stress. Chaperones.
, vol.6
, pp. 238-246
-
-
Krishna, P.1
Gloor, G.2
-
5
-
-
0028785298
-
Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species
-
Gupta, R. S. (1995) Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species. Mol. Biol. Evol.,12, 1063-1073.
-
(1995)
Mol. Biol. Evol.
, vol.12
, pp. 1063-1073
-
-
Gupta, R.S.1
-
6
-
-
0037121087
-
Phylogenetic relationships of organellar Hsp90 homologs reveal fundamental differences to organellar Hsp70 and Hsp60 evolution
-
Emelyanov, V. V. (2002) Phylogenetic relationships of organellar Hsp90 homologs reveal fundamental differences to organellar Hsp70 and Hsp60 evolution. Gene,299, 125-133.
-
(2002)
Gene
, vol.299
, pp. 125-133
-
-
Emelyanov, V.V.1
-
7
-
-
0030462612
-
Two eukaryotespecific regions of Hsp82 are dispensable for its viability and signal transduction functions in yeast
-
Louvion, J. F., Warth, R., and Picard, D. (1996) Two eukaryotespecific regions of Hsp82 are dispensable for its viability and signal transduction functions in yeast. Proc. Natl. Acad. Sci. U.S.A,93, 13937-13942.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 13937-13942
-
-
Louvion, J.F.1
Warth, R.2
Picard, D.3
-
8
-
-
0034646511
-
Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine
-
Scheufler, C., Brinker, A., Bourenkov, G., Pegoraro, S., Moroder, L., Bartunik, H., Hartl, F. U., and Moarefi, I. (2000) Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell,101, 199-210.
-
(2000)
Cell
, vol.101
, pp. 199-210
-
-
Scheufler, C.1
Brinker, A.2
Bourenkov, G.3
Pegoraro, S.4
Moroder, L.5
Bartunik, H.6
Hartl, F.U.7
Moarefi, I.8
-
9
-
-
0031846768
-
Differential interactions of p23 and the TPR-containing proteins Hop, Cyp40, FKBP52 and FKBP51 with Hsp90 mutants
-
Chen, S., Sullivan, W. P., Toft, D. O., and Smith, D. F. (1998) Differential interactions of p23 and the TPR-containing proteins Hop, Cyp40, FKBP52 and FKBP51 with Hsp90 mutants. Cell Stress. Chaperones.,3, 118-129.
-
(1998)
Cell Stress. Chaperones.
, vol.3
, pp. 118-129
-
-
Chen, S.1
Sullivan, W.P.2
Toft, D.O.3
Smith, D.F.4
-
10
-
-
0030087795
-
Characterization of a plastid-specific HSP90 homologue: identification of a cDNA sequence, phylogenetic descendence and analysis of its mRNA and protein expression
-
Schmitz, G., Schmidt, M., and Feierabend, J. (1996) Characterization of a plastid-specific HSP90 homologue: identification of a cDNA sequence, phylogenetic descendence and analysis of its mRNA and protein expression. Plant Mol. Biol.,30, 479-492.
-
(1996)
Plant Mol. Biol.
, vol.30
, pp. 479-492
-
-
Schmitz, G.1
Schmidt, M.2
Feierabend, J.3
-
11
-
-
0034603178
-
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties
-
Felts, S. J., Owen, B. A., Nguyen, P., Trepel, J., Donner, D. B., and Toft, D. O. (2000) The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties. J. Biol. Chem.,275, 3305-3312.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3305-3312
-
-
Felts, S.J.1
Owen, B.A.2
Nguyen, P.3
Trepel, J.4
Donner, D.B.5
Toft, D.O.6
-
12
-
-
0024044382
-
Ancient heat shock gene is dispensable
-
Bardwell, J. C. and Craig, E. A. (1988) Ancient heat shock gene is dispensable. J. Bacteriol.,170, 2977-2983.
-
(1988)
J. Bacteriol.
, vol.170
, pp. 2977-2983
-
-
Bardwell, J.C.1
Craig, E.A.2
-
13
-
-
0032840055
-
HtpG is essential for the thermal stress management in cyanobacteria
-
Tanaka, N. and Nakamoto, H. (1999) HtpG is essential for the thermal stress management in cyanobacteria. FEBS Lett.,458, 117-123.
-
(1999)
FEBS Lett.
, vol.458
, pp. 117-123
-
-
Tanaka, N.1
Nakamoto, H.2
-
14
-
-
0032931842
-
A trans-activation domain in yeast heat shock transcription factor is essential for cell cycle progression during stress
-
Morano, K. A., Santoro, N., Koch, K. A., and Thiele, D. J. (1999) A trans-activation domain in yeast heat shock transcription factor is essential for cell cycle progression during stress. Mol. Cell Biol.,19, 402-411.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 402-411
-
-
Morano, K.A.1
Santoro, N.2
Koch, K.A.3
Thiele, D.J.4
-
15
-
-
0034614431
-
Herbimycin A induces G1 arrest through accumulation of p27(Kip1) in cyclin D1-overexpressing fibroblasts
-
Endo, N., Tashiro, E., Umezawa, K., Kawada, M., Uehara, Y., Doki, Y., Weinstein, I. B., and Imoto, M. (2000) Herbimycin A induces G1 arrest through accumulation of p27(Kip1) in cyclin D1-overexpressing fibroblasts. Biochem. Biophys. Res. Commun.,267, 54-58.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.267
, pp. 54-58
-
-
Endo, N.1
Tashiro, E.2
Umezawa, K.3
Kawada, M.4
Uehara, Y.5
Doki, Y.6
Weinstein, I.B.7
Imoto, M.8
-
16
-
-
0034665760
-
Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G(1) phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex
-
Shiotsu, Y., Neckers, L. M., Wortman, I., An, W. G., Schulte, T. W., Soga, S., Murakata, C., Tamaoki, T., and Akinaga, S. (2000) Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G(1) phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex. Blood,96, 2284-2291.
-
(2000)
Blood
, vol.96
, pp. 2284-2291
-
-
Shiotsu, Y.1
Neckers, L.M.2
Wortman, I.3
An, W.G.4
Schulte, T.W.5
Soga, S.6
Murakata, C.7
Tamaoki, T.8
Akinaga, S.9
-
17
-
-
0029838168
-
Physical interaction of mammalian CDC37 with CDK4
-
Dai, K., Kobayashi, R., and Beach, D. (1996) Physical interaction of mammalian CDC37 with CDK4. J. Biol. Chem.,271, 22030-22034.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22030-22034
-
-
Dai, K.1
Kobayashi, R.2
Beach, D.3
-
18
-
-
0035898534
-
The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNAdependent kinase PKR
-
Donze, O., Abbas-Terki, T., and Picard, D. (2001) The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNAdependent kinase PKR. EMBO J.,20, 3771-3780.
-
(2001)
EMBO J.
, vol.20
, pp. 3771-3780
-
-
Donze, O.1
Abbas-Terki, T.2
Picard, D.3
-
19
-
-
0028589101
-
A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90
-
Aligue, R., Akhavan-Niak, H., and Russell, P. (1994) A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90. EMBO J.,13, 6099-6106.
-
(1994)
EMBO J.
, vol.13
, pp. 6099-6106
-
-
Aligue, R.1
Akhavan-Niak, H.2
Russell, P.3
-
20
-
-
0032569851
-
Hsp90 as a capacitor for morphological evolution
-
Rutherford, S. L. and Lindquist, S. (1998) Hsp90 as a capacitor for morphological evolution. Nature,396, 336-342.
-
(1998)
Nature
, vol.396
, pp. 336-342
-
-
Rutherford, S.L.1
Lindquist, S.2
-
21
-
-
0037030713
-
Hsp90 as a capacitor of phenotypic variation
-
Queitsch, C., Sangster, T. A., and Lindquist, S. (2002) Hsp90 as a capacitor of phenotypic variation. Nature,417, 618-624.
-
(2002)
Nature
, vol.417
, pp. 618-624
-
-
Queitsch, C.1
Sangster, T.A.2
Lindquist, S.3
-
22
-
-
0033621681
-
Mice lacking HSP90beta fail to develop a placental labyrinth
-
Voss, A. K., Thomas, T., and Gruss, P. (2000) Mice lacking HSP90beta fail to develop a placental labyrinth. Development,127, 1-11.
-
(2000)
Development
, vol.127
, pp. 1-11
-
-
Voss, A.K.1
Thomas, T.2
Gruss, P.3
-
23
-
-
0033152937
-
Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90
-
Lele, Z., Hartson, S. D., Martin, C. C., Whitesell, L., Matts, R. L., and Krone, P. H. (1999) Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90. Dev. Biol.,210, 56-70.
-
(1999)
Dev. Biol.
, vol.210
, pp. 56-70
-
-
Lele, Z.1
Hartson, S.D.2
Martin, C.C.3
Whitesell, L.4
Matts, R.L.5
Krone, P.H.6
-
24
-
-
0034795208
-
Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability
-
Randow, F. and Seed, B. (2001) Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability. Nat. Cell Biol.,3, 891-896.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 891-896
-
-
Randow, F.1
Seed, B.2
-
25
-
-
0037073712
-
Activation of an Unfolded Protein Response during Differentiation of Antibody-secreting B Cells
-
Gass, J. N., Gifford, N. M., and Brewer, J. W. (2002) Activation of an Unfolded Protein Response during Differentiation of Antibody-secreting B Cells. J. Biol. Chem.,277, 49047-49054.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49047-49054
-
-
Gass, J.N.1
Gifford, N.M.2
Brewer, J.W.3
-
26
-
-
0036911213
-
A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins
-
Meunier, L., Usherwood, Y. K., Chung, K. T., and Hendershot, L. M. (2002) A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. Mol. Biol. Cell,13, 4456-4469.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 4456-4469
-
-
Meunier, L.1
Usherwood, Y.K.2
Chung, K.T.3
Hendershot, L.M.4
-
28
-
-
0037040975
-
The role of Hsp90N, a new member of the Hsp90 family, in signal transduction and neoplastic transformation
-
Grammatikakis, N., Vultur, A., Ramana, C. V., Siganou, A., Schweinfest, C. W., Watson, D. K., and Raptis, L. (2002) The role of Hsp90N, a new member of the Hsp90 family, in signal transduction and neoplastic transformation. J. Biol. Chem.,277, 8312-8320.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8312-8320
-
-
Grammatikakis, N.1
Vultur, A.2
Ramana, C.V.3
Siganou, A.4
Schweinfest, C.W.5
Watson, D.K.6
Raptis, L.7
-
29
-
-
0025604419
-
Some effects of growth conditions on steady state and heat shock induced htpG gene expression in continuous cultures of Escherichia coli
-
Heitzer, A., Mason, C. A., Snozzi, M., and Hamer, G. (1990) Some effects of growth conditions on steady state and heat shock induced htpG gene expression in continuous cultures of Escherichia coli. Arch. Microbiol.,155, 7-12.
-
(1990)
Arch. Microbiol.
, vol.155
, pp. 7-12
-
-
Heitzer, A.1
Mason, C.A.2
Snozzi, M.3
Hamer, G.4
-
30
-
-
0036118388
-
Correlation between acetaldehyde and ethanol resistance and expression of HSP genes in yeast strains isolated during the biological aging of sherry wines
-
Aranda, A., Querol, A., and del Olmo, M. (2002) Correlation between acetaldehyde and ethanol resistance and expression of HSP genes in yeast strains isolated during the biological aging of sherry wines. Arch. Microbiol.,177, 304-312.
-
(2002)
Arch. Microbiol.
, vol.177
, pp. 304-312
-
-
Aranda, A.1
Querol, A.2
Del Olmo, M.3
-
31
-
-
0023683820
-
Isolation and characterization of Escherichia coli mutants that lack the heat shock sigma factor sigma 32
-
Zhou, Y. N., Kusukawa, N., Erickson, J. W., Gross, C. A., and Yura, T. (1988) Isolation and characterization of Escherichia coli mutants that lack the heat shock sigma factor sigma 32. J. Bacteriol.,170, 3640-3649.
-
(1988)
J. Bacteriol.
, vol.170
, pp. 3640-3649
-
-
Zhou, Y.N.1
Kusukawa, N.2
Erickson, J.W.3
Gross, C.A.4
Yura, T.5
-
32
-
-
1842332785
-
Consensus sequence for Escherichia coli heat shock gene promoters
-
Cowing, D. W., Bardwell, J. C., Craig, E. A., Woolford, C., Hendrix, R. W., and Gross, C. A. (1985) Consensus sequence for Escherichia coli heat shock gene promoters. Proc. Natl. Acad. Sci. U.S.A,82, 2679-2683.
-
(1985)
Proc. Natl. Acad. Sci. U.S.A
, vol.82
, pp. 2679-2683
-
-
Cowing, D.W.1
Bardwell, J.C.2
Craig, E.A.3
Woolford, C.4
Hendrix, R.W.5
Gross, C.A.6
-
33
-
-
0027475243
-
Hsp90 chaperonins possess ATPase activity and bind heat shock transcription factors and peptidyl prolyl isomerases
-
Nadeau, K., Das, A., and Walsh, C. T. (1993) Hsp90 chaperonins possess ATPase activity and bind heat shock transcription factors and peptidyl prolyl isomerases. J. Biol. Chem.,268, 1479-1487.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1479-1487
-
-
Nadeau, K.1
Das, A.2
Walsh, C.T.3
-
34
-
-
0030779154
-
A yeast heat shock transcription factor (Hsf1) mutant is defective in both Hsc82/Hsp82 synthesis and spindle pole body duplication
-
Zarzov, P., Boucherie, H., and Mann, C. (1997). A yeast heat shock transcription factor (Hsf1) mutant is defective in both Hsc82/Hsp82 synthesis and spindle pole body duplication. J. Cell Sci., 110 (PT 16), 1879-1891.
-
(1997)
J. Cell Sci.
, vol.110
, Issue.16 PT
, pp. 1879-1891
-
-
Zarzov, P.1
Boucherie, H.2
Mann, C.3
-
35
-
-
0035881744
-
The loop domain of heat shock transcription factor 1 dictates DNAbinding specificity and responses to heat stress
-
Ahn, S. G., Liu, P. C., Klyachko, K., Morimoto, R. I., and Thiele, D. J. (2001) The loop domain of heat shock transcription factor 1 dictates DNAbinding specificity and responses to heat stress. Genes Dev.,15, 2134-2145.
-
(2001)
Genes Dev.
, vol.15
, pp. 2134-2145
-
-
Ahn, S.G.1
Liu, P.C.2
Klyachko, K.3
Morimoto, R.I.4
Thiele, D.J.5
-
36
-
-
0025076362
-
Promoter function and in situ protein/DNA interactions upstream of the yeast HSP90 heat shock genes
-
Gross, D. S., Adams, C. C., English, K. E., Collins, K. W., and Lee, S. (1990) Promoter function and in situ protein/DNA interactions upstream of the yeast HSP90 heat shock genes. Antonie Van Leeuwenhoek,58, 175-186.
-
(1990)
Antonie Van Leeuwenhoek
, vol.58
, pp. 175-186
-
-
Gross, D.S.1
Adams, C.C.2
English, K.E.3
Collins, K.W.4
Lee, S.5
-
37
-
-
0025678738
-
Genomic footprinting of the yeast HSP82 promoter reveals marked distortion of the DNA helix and constitutive occupancy of heat shock and TATA elements
-
Gross, D. S., English, K. E., Collins, K. W., and Lee, S. W. (1990) Genomic footprinting of the yeast HSP82 promoter reveals marked distortion of the DNA helix and constitutive occupancy of heat shock and TATA elements. J. Mol. Biol.,216, 611-631.
-
(1990)
J. Mol. Biol.
, vol.216
, pp. 611-631
-
-
Gross, D.S.1
English, K.E.2
Collins, K.W.3
Lee, S.W.4
-
38
-
-
0029026401
-
Multiple protein-DNA interactions over the yeast HSC82 heat shock gene promoter
-
Erkine, A. M., Adams, C. C., Gao, M., and Gross, D. S. (1995) Multiple protein-DNA interactions over the yeast HSC82 heat shock gene promoter. Nucleic Acids Res.,23, 1822-1829.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 1822-1829
-
-
Erkine, A.M.1
Adams, C.C.2
Gao, M.3
Gross, D.S.4
-
39
-
-
0032986822
-
Interleukin-10 activates heatshock protein 90beta gene expression
-
Ripley, B. J., Stephanou, A., Isenberg, D. A., and Latchman, D. S. (1999) Interleukin-10 activates heatshock protein 90beta gene expression. Immunology,97, 226-231.
-
(1999)
Immunology
, vol.97
, pp. 226-231
-
-
Ripley, B.J.1
Stephanou, A.2
Isenberg, D.A.3
Latchman, D.S.4
-
40
-
-
0030748520
-
Essential role of the first intron in the transcription of hsp90beta gene
-
Shen, Y., Liu, J., Wang, X., Cheng, X., Wang, Y., and Wu, N. (1997) Essential role of the first intron in the transcription of hsp90beta gene. FEBS Lett.,413, 92-98.
-
(1997)
FEBS Lett.
, vol.413
, pp. 92-98
-
-
Shen, Y.1
Liu, J.2
Wang, X.3
Cheng, X.4
Wang, Y.5
Wu, N.6
-
41
-
-
0032588963
-
Regulation of human hsp90alpha gene expression
-
Zhang, S. L., Yu, J., Cheng, X. K., Ding, L., Heng, F. Y., Wu, N. H., and Shen, Y. F. (1999) Regulation of human hsp90alpha gene expression. FEBS Lett.,444, 130-135.
-
(1999)
FEBS Lett.
, vol.444
, pp. 130-135
-
-
Zhang, S.L.1
Yu, J.2
Cheng, X.K.3
Ding, L.4
Heng, F.Y.5
Wu, N.H.6
Shen, Y.F.7
-
42
-
-
0036708568
-
HSP90alpha, HSP90beta, and p53 expression following in vitro hyperthermia exposure in gestation day 10 rat embryos
-
Dugyala, R. R., Claggett, T. W., Kimmel, G. L., and Kimmel, C. A. (2002) HSP90alpha, HSP90beta, and p53 expression following in vitro hyperthermia exposure in gestation day 10 rat embryos. Toxicol. Sci.,69, 183-190.
-
(2002)
Toxicol. Sci.
, vol.69
, pp. 183-190
-
-
Dugyala, R.R.1
Claggett, T.W.2
Kimmel, G.L.3
Kimmel, C.A.4
-
43
-
-
0346435106
-
PKC epsilon is a unique regulator for hsp90 beta gene in heat shock response
-
Wu, J. M., Xiao, L., Cheng, X. K., Cui, L. X., Wu, N. H., and Shen, Y. F. (2003) PKC epsilon is a unique regulator for hsp90 beta gene in heat shock response. J. Biol. Chem.,278, 51143-51149.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51143-51149
-
-
Wu, J.M.1
Xiao, L.2
Cheng, X.K.3
Cui, L.X.4
Wu, N.H.5
Shen, Y.F.6
-
44
-
-
1642268986
-
Hsp90 isoforms: functions, expression and clinical importance
-
Sreedhar, A. S., Kalmar, E., Csermely, P., and Shen, Y. F. (2004) Hsp90 isoforms: functions, expression and clinical importance. FEBS Lett.,562, 11-15.
-
(2004)
FEBS Lett.
, vol.562
, pp. 11-15
-
-
Sreedhar, A.S.1
Kalmar, E.2
Csermely, P.3
Shen, Y.F.4
-
45
-
-
0347285295
-
A trip to the ER: coping with stress
-
Rutkowski, D. T. and Kaufman, R. J. (2004) A trip to the ER: coping with stress. Trends Cell Biol.,14, 20-28.
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 20-28
-
-
Rutkowski, D.T.1
Kaufman, R.J.2
-
46
-
-
0034694896
-
Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast
-
Okamura, K., Kimata, Y., Higashio, H., Tsuru, A., and Kohno, K. (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem. Biophys. Res. Commun.,279, 445-450.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.279
, pp. 445-450
-
-
Okamura, K.1
Kimata, Y.2
Higashio, H.3
Tsuru, A.4
Kohno, K.5
-
47
-
-
0038308388
-
Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins
-
Kimata, Y., Kimata, Y. I., Shimizu, Y., Abe, H., Farcasanu, I. C., Takeuchi, M., Rose, M. D., and Kohno, K. (2003) Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. Mol. Biol. Cell,14, 2559-2569.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 2559-2569
-
-
Kimata, Y.1
Kimata, Y.I.2
Shimizu, Y.3
Abe, H.4
Farcasanu, I.C.5
Takeuchi, M.6
Rose, M.D.7
Kohno, K.8
-
48
-
-
0035370949
-
Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals
-
Patil, C. and Walter, P. (2001) Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr. Opin. Cell Biol.,13, 349-355.
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 349-355
-
-
Patil, C.1
Walter, P.2
-
50
-
-
0017356625
-
Cytotoxic activity of macrocyclic metabolites from fungi
-
Horakova, K. and Betina, V. (1977) Cytotoxic activity of macrocyclic metabolites from fungi. Neoplasma,24, 21-27.
-
(1977)
Neoplasma
, vol.24
, pp. 21-27
-
-
Horakova, K.1
Betina, V.2
-
51
-
-
0016393109
-
Geldanamycin biosynthesis and carbon magnetic resonance
-
Johnson, R. D., Haber, A., and Rinehart, K. L., Jr. (1974) Geldanamycin biosynthesis and carbon magnetic resonance. J. Am. Chem. Soc.,96, 3316-3317.
-
(1974)
J. Am. Chem. Soc.
, vol.96
, pp. 3316-3317
-
-
Johnson, R.D.1
Haber, A.2
Rinehart Jr., K.L.3
-
52
-
-
0018899108
-
Macbecins I and II, new antitumor antibiotics.II. Isolation and characterization
-
Muroi, M., Izawa, M., Kosai, Y., and Asai, M. (1980) Macbecins I and II, new antitumor antibiotics. II. Isolation and characterization. J. Antibiot. (Tokyo),33, 205-212.
-
(1980)
J. Antibiot. (Tokyo)
, vol.33
, pp. 205-212
-
-
Muroi, M.1
Izawa, M.2
Kosai, Y.3
Asai, M.4
-
53
-
-
0018856776
-
Macbecins I and II, new antitumor antibiotics.I. Producing organism, fermentation and antimicrobial activities
-
Tanida, S., Hasegawa, T., and Higashide, E. (1980) Macbecins I and II, new antitumor antibiotics. I. Producing organism, fermentation and antimicrobial activities. J. Antibiot. (Tokyo),33, 199-204.
-
(1980)
J. Antibiot. (Tokyo)
, vol.33
, pp. 199-204
-
-
Tanida, S.1
Hasegawa, T.2
Higashide, E.3
-
54
-
-
0021213896
-
Chemical modification and antitumor activity of herbimycin .8,9-Epoxide, 7,9-cyclic carbamate, and 17 or 19-amino derivatives
-
Omura, S., Miyano, K., Nakagawa, A., Sano, H., Komiyama, K., Umezawa, I., Shibata, K., and Satsumabayashi, S. (1984) Chemical modification and antitumor activity of herbimycin . 8,9-Epoxide, 7,9-cyclic carbamate, and 17 or 19-amino derivatives. J. Antibiot. (Tokyo),37, 1264-1267.
-
(1984)
J. Antibiot. (Tokyo)
, vol.37
, pp. 1264-1267
-
-
Omura, S.1
Miyano, K.2
Nakagawa, A.3
Sano, H.4
Komiyama, K.5
Umezawa, I.6
Shibata, K.7
Satsumabayashi, S.8
-
55
-
-
0018393611
-
Herbimycin, a new antibiotic produced by a strain of Streptomyces
-
Omura, S., Iwai, Y., Takahashi, Y., Sadakane, N., Nakagawa, A., Oiwa, H., Hasegawa, Y., and Ikai, T. (1979) Herbimycin, a new antibiotic produced by a strain of Streptomyces. J. Antibiot. (Tokyo),32, 255-261.
-
(1979)
J. Antibiot. (Tokyo)
, vol.32
, pp. 255-261
-
-
Omura, S.1
Iwai, Y.2
Takahashi, Y.3
Sadakane, N.4
Nakagawa, A.5
Oiwa, H.6
Hasegawa, Y.7
Ikai, T.8
-
56
-
-
0022967572
-
Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus
-
Uehara, Y., Hori, M., Takeuchi, T., and Umezawa, H. (1986) Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus. Mol. Cell Biol.,6, 2198-2206.
-
(1986)
Mol. Cell Biol.
, vol.6
, pp. 2198-2206
-
-
Uehara, Y.1
Hori, M.2
Takeuchi, T.3
Umezawa, H.4
-
57
-
-
0141708701
-
Natural product origins of Hsp90 inhibitors
-
Uehara, Y. (2003) Natural product origins of Hsp90 inhibitors. Curr. Cancer Drug Targets.,3, 325-330.
-
(2003)
Curr. Cancer Drug Targets.
, vol.3
, pp. 325-330
-
-
Uehara, Y.1
-
58
-
-
0029973294
-
Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells
-
Whitesell, L. and Cook, P. (1996) Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. Mol. Endocrinol.,10, 705-712.
-
(1996)
Mol. Endocrinol.
, vol.10
, pp. 705-712
-
-
Whitesell, L.1
Cook, P.2
-
59
-
-
0033863883
-
The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome
-
An, W. G., Schulte, T. W., and Neckers, L. M. (2000) The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome. Cell Growth Differ.,11, 355-360.
-
(2000)
Cell Growth Differ.
, vol.11
, pp. 355-360
-
-
An, W.G.1
Schulte, T.W.2
Neckers, L.M.3
-
60
-
-
0029963674
-
Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90
-
Schneider, C., Sepp-Lorenzino, L., Nimmesgern, E., Ouerfelli, O., Danishefsky, S., Rosen, N., and Hartl, F. U. (1996) Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90. Proc. Natl. Acad. Sci. U.S.A,93, 14536-14541.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 14536-14541
-
-
Schneider, C.1
Sepp-Lorenzino, L.2
Nimmesgern, E.3
Ouerfelli, O.4
Danishefsky, S.5
Rosen, N.6
Hartl, F.U.7
-
61
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent
-
Stebbins, C. E., Russo, A. A., Schneider, C., Rosen, N., Hartl, F. U., and Pavletich, N. P. (1997) Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell,89, 239-250.
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
Rosen, N.4
Hartl, F.U.5
Pavletich, N.P.6
-
62
-
-
0032959590
-
Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin
-
Roe, S. M., Prodromou, C., O'Brien, R., Ladbury, J. E., Piper, P. W., and Pearl, L. H. (1999) Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin. J. Med. Chem.,42, 260-266.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 260-266
-
-
Roe, S.M.1
Prodromou, C.2
O'Brien, R.3
Ladbury, J.E.4
Piper, P.W.5
Pearl, L.H.6
-
63
-
-
0036219609
-
Hsp90 inhibitors as novel cancer chemotherapeutic agents
-
Neckers, L. (2002). Hsp90 inhibitors as novel cancer chemotherapeutic agents. Trends Mol. Med., 8, S55-S61.
-
(2002)
Trends Mol. Med.
, vol.8
-
-
Neckers, L.1
-
64
-
-
1542298267
-
Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone
-
Workman, P. (2004) Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone. Cancer Lett.,206, 149-157.
-
(2004)
Cancer Lett.
, vol.206
, pp. 149-157
-
-
Workman, P.1
-
65
-
-
0033579175
-
DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90
-
Kelland, L. R., Sharp, S. Y., Rogers, P. M., Myers, T. G., and Workman, P. (1999) DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90. J. Natl. Cancer Inst.,91, 1940-1949.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1940-1949
-
-
Kelland, L.R.1
Sharp, S.Y.2
Rogers, P.M.3
Myers, T.G.4
Workman, P.5
-
66
-
-
0141596326
-
Clinical development of 17-allylamino, 17-demethoxygeldanamycin
-
Sausville, E. A., Tomaszewski, J. E., and Ivy, P. (2003) Clinical development of 17-allylamino, 17-demethoxygeldanamycin. Curr. Cancer Drug Targets.,3, 377-383.
-
(2003)
Curr. Cancer Drug Targets.
, vol.3
, pp. 377-383
-
-
Sausville, E.A.1
Tomaszewski, J.E.2
Ivy, P.3
-
67
-
-
0141484615
-
A highaffinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
-
Kamal, A., Thao, L., Sensintaffar, J., Zhang, L., Boehm, M. F., Fritz, L. C., and Burrows, F. J. (2003) A highaffinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature,425, 407-410.
-
(2003)
Nature
, vol.425
, pp. 407-410
-
-
Kamal, A.1
Thao, L.2
Sensintaffar, J.3
Zhang, L.4
Boehm, M.F.5
Fritz, L.C.6
Burrows, F.J.7
-
68
-
-
1642503079
-
High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity
-
Rowlands, M. G., Newbatt, Y. M., Prodromou, C., Pearl, L. H., Workman, P., and Aherne, W. (2004) High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity. Anal. Biochem.,327, 176-183.
-
(2004)
Anal. Biochem.
, vol.327
, pp. 176-183
-
-
Rowlands, M.G.1
Newbatt, Y.M.2
Prodromou, C.3
Pearl, L.H.4
Workman, P.5
Aherne, W.6
-
69
-
-
0035071607
-
A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells
-
Chiosis, G., Timaul, M. N., Lucas, B., Munster, P. N., Zheng, F. F., Sepp-Lorenzino, L., and Rosen, N. (2001) A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells. Chem. Biol.,8, 289-299.
-
(2001)
Chem. Biol.
, vol.8
, pp. 289-299
-
-
Chiosis, G.1
Timaul, M.N.2
Lucas, B.3
Munster, P.N.4
Zheng, F.F.5
Sepp-Lorenzino, L.6
Rosen, N.7
-
70
-
-
0141485327
-
Development of purinescaffold small molecule inhibitors of Hsp90
-
Chiosis, G., Lucas, B., Huezo, H., Solit, D., Basso, A., and Rosen, N. (2003) Development of purinescaffold small molecule inhibitors of Hsp90. Curr. Cancer Drug Targets.,3, 371-376.
-
(2003)
Curr. Cancer Drug Targets.
, vol.3
, pp. 371-376
-
-
Chiosis, G.1
Lucas, B.2
Huezo, H.3
Solit, D.4
Basso, A.5
Rosen, N.6
-
71
-
-
0037315208
-
Regulation of signaling protein function and trafficking by the hsp90/ hsp70-based chaperone machinery
-
Pratt, W. B. and Toft, D. O. (2003) Regulation of signaling protein function and trafficking by the hsp90/ hsp70-based chaperone machinery. Exp. Biol. Med. (Maywood.),228, 111-133.
-
(2003)
Exp. Biol. Med. (Maywood.)
, vol.228
, pp. 111-133
-
-
Pratt, W.B.1
Toft, D.O.2
-
72
-
-
0029737509
-
Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90
-
Blagosklonny, M. V., Toretsky, J., Bohen, S., and Neckers, L. (1996) Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90. Proc. Natl. Acad. Sci. U.S.A,93, 8379-8383.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 8379-8383
-
-
Blagosklonny, M.V.1
Toretsky, J.2
Bohen, S.3
Neckers, L.4
-
73
-
-
0032555685
-
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stresssensitive complex with HSF1
-
Zou, J., Guo, Y., Guettouche, T., Smith, D. F., and Voellmy, R. (1998) Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stresssensitive complex with HSF1. Cell,94, 471-480.
-
(1998)
Cell
, vol.94
, pp. 471-480
-
-
Zou, J.1
Guo, Y.2
Guettouche, T.3
Smith, D.F.4
Voellmy, R.5
-
74
-
-
0030901877
-
A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone
-
Prodromou, C., Roe, S. M., Piper, P. W., and Pearl, L. H. (1997) A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone. Nat. Struct. Biol.,4, 477-482.
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 477-482
-
-
Prodromou, C.1
Roe, S.M.2
Piper, P.W.3
Pearl, L.H.4
-
75
-
-
0031444238
-
Identification and structural characterization of the ATP/ ADP-binding site in the Hsp90 molecular chaperone
-
Prodromou, C., Roe, S. M., O'Brien, R., Ladbury, J. E., Piper, P. W., and Pearl, L. H. (1997) Identification and structural characterization of the ATP/ ADP-binding site in the Hsp90 molecular chaperone. Cell,90, 65-75.
-
(1997)
Cell
, vol.90
, pp. 65-75
-
-
Prodromou, C.1
Roe, S.M.2
O'Brien, R.3
Ladbury, J.E.4
Piper, P.W.5
Pearl, L.H.6
-
76
-
-
0026428621
-
Crystal structure of an N-terminal fragment of the DNA gyrase B protein
-
Wigley, D. B., Davies, G. J., Dodson, E. J., Maxwell, A., and Dodson, G. (1991) Crystal structure of an N-terminal fragment of the DNA gyrase B protein. Nature,351, 624-629.
-
(1991)
Nature
, vol.351
, pp. 624-629
-
-
Wigley, D.B.1
Davies, G.J.2
Dodson, E.J.3
Maxwell, A.4
Dodson, G.5
-
77
-
-
0033985080
-
GHKL, an emergent ATPase/kinase superfamily
-
Dutta, R. and Inouye, M. (2000) GHKL, an emergent ATPase/kinase superfamily. Trends Biochem. Sci.,25, 24-28.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 24-28
-
-
Dutta, R.1
Inouye, M.2
-
78
-
-
0034737716
-
Dimerization of Escherichia coli DNAgyrase B provides a structural mechanism for activating the ATPase catalytic center
-
Brino, L., Urzhumtsev, A., Mousli, M., Bronner, C., Mitschler, A., Oudet, P., and Moras, D. (2000) Dimerization of Escherichia coli DNAgyrase B provides a structural mechanism for activating the ATPase catalytic center. J. Biol. Chem.,275, 9468-9475.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9468-9475
-
-
Brino, L.1
Urzhumtsev, A.2
Mousli, M.3
Bronner, C.4
Mitschler, A.5
Oudet, P.6
Moras, D.7
-
79
-
-
0033515522
-
Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair
-
Ban, C., Junop, M., and Yang, W. (1999) Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. Cell,97, 85-97.
-
(1999)
Cell
, vol.97
, pp. 85-97
-
-
Ban, C.1
Junop, M.2
Yang, W.3
-
80
-
-
0037352446
-
Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions
-
Meyer, P., Prodromou, C., Hu, B., Vaughan, C., Roe, S. M., Panaretou, B., Piper, P. W., and Pearl, L. H. (2003) Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions. Mol. Cell,11, 647-658.
-
(2003)
Mol. Cell
, vol.11
, pp. 647-658
-
-
Meyer, P.1
Prodromou, C.2
Hu, B.3
Vaughan, C.4
Roe, S.M.5
Panaretou, B.6
Piper, P.W.7
Pearl, L.H.8
-
81
-
-
0032541344
-
ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo
-
Panaretou, B., Prodromou, C., Roe, S. M., O'Brien, R., Ladbury, J. E., Piper, P. W., and Pearl, L. H. (1998) ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo. EMBO J.,17, 4829-4836.
-
(1998)
EMBO J.
, vol.17
, pp. 4829-4836
-
-
Panaretou, B.1
Prodromou, C.2
Roe, S.M.3
O'Brien, R.4
Ladbury, J.E.5
Piper, P.W.6
Pearl, L.H.7
-
82
-
-
0032539709
-
Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence
-
Scheibel, T., Weikl, T., and Buchner, J. (1998) Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence. Proc. Natl. Acad. Sci. U.S.A,95, 1495-1499.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A
, vol.95
, pp. 1495-1499
-
-
Scheibel, T.1
Weikl, T.2
Buchner, J.3
-
83
-
-
0034663806
-
The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains
-
Prodromou, C., Panaretou, B., Chohan, S., Siligardi, G., O'Brien, R., Ladbury, J. E., Roe, S. M., Piper, P. W., and Pearl, L. H. (2000) The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains. EMBO J.,19, 4383-4392.
-
(2000)
EMBO J.
, vol.19
, pp. 4383-4392
-
-
Prodromou, C.1
Panaretou, B.2
Chohan, S.3
Siligardi, G.4
O'Brien, R.5
Ladbury, J.E.6
Roe, S.M.7
Piper, P.W.8
Pearl, L.H.9
-
84
-
-
0034602451
-
C-terminal regions of Hsp90 are important for trapping the nucleotide during the ATPase cycle
-
Weikl, T., Muschler, P., Richter, K., Veit, T., Reinstein, J., and Buchner, J. (2000) C-terminal regions of Hsp90 are important for trapping the nucleotide during the ATPase cycle. J. Mol. Biol.,303, 583-592.
-
(2000)
J. Mol. Biol.
, vol.303
, pp. 583-592
-
-
Weikl, T.1
Muschler, P.2
Richter, K.3
Veit, T.4
Reinstein, J.5
Buchner, J.6
-
85
-
-
0035823582
-
Coordinated ATP hydrolysis by the Hsp90 dimer
-
Richter, K., Muschler, P., Hainzl, O., and Buchner, J. (2001) Coordinated ATP hydrolysis by the Hsp90 dimer. J. Biol. Chem.,276, 33689-33696.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33689-33696
-
-
Richter, K.1
Muschler, P.2
Hainzl, O.3
Buchner, J.4
-
86
-
-
0141994917
-
Dissection of the contribution of individual domains to the ATPase mechanism of Hsp90
-
Wegele, H., Muschler, P., Bunck, M., Reinstein, J., and Buchner, J. (2003) Dissection of the contribution of individual domains to the ATPase mechanism of Hsp90. J. Biol. Chem.,278, 39303-39310.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39303-39310
-
-
Wegele, H.1
Muschler, P.2
Bunck, M.3
Reinstein, J.4
Buchner, J.5
-
87
-
-
0033741503
-
Dimerization and N-terminal domain proximity underlie the function of the molecular chaperone heat shock protein 90
-
Chadli, A., Bouhouche, I., Sullivan, W., Stensgard, B., McMahon, N., Catelli, M. G., and Toft, D. O. (2000) Dimerization and N-terminal domain proximity underlie the function of the molecular chaperone heat shock protein 90. Proc. Natl. Acad. Sci. U.S.A,97, 12524-12529.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 12524-12529
-
-
Chadli, A.1
Bouhouche, I.2
Sullivan, W.3
Stensgard, B.4
McMahon, N.5
Catelli, M.G.6
Toft, D.O.7
-
88
-
-
0346037322
-
N-terminal residues regulate the catalytic efficiency of the Hsp90 ATPase cycle
-
Richter, K., Reinstein, J., and Buchner, J. (2002) N-terminal residues regulate the catalytic efficiency of the Hsp90 ATPase cycle. J. Biol. Chem.,277, 44905-44910.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44905-44910
-
-
Richter, K.1
Reinstein, J.2
Buchner, J.3
-
89
-
-
0030863995
-
The aminoterminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation
-
Grenert, J. P., Sullivan, W. P., Fadden, P., Haystead, T. A., Clark, J., Mimnaugh, E., Krutzsch, H., Ochel, H. J., Schulte, T. W., Sausville, E., Neckers, L. M., and Toft, D. O. (1997) The aminoterminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation. J. Biol. Chem.,272, 23843-23850.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23843-23850
-
-
Grenert, J.P.1
Sullivan, W.P.2
Fadden, P.3
Haystead, T.A.4
Clark, J.5
Mimnaugh, E.6
Krutzsch, H.7
Ochel, H.J.8
Schulte, T.W.9
Sausville, E.10
Neckers, L.M.11
Toft, D.O.12
-
90
-
-
0141683523
-
NMR Chemical Shift Perturbation Study of the NTerminal Domain of Hsp90 upon Binding of ADP, AMP-PNP, Geldanamycin, and Radicicol
-
Dehner, A., Furrer, J., Richter, K., Schuster, I., Buchner, J., and Kessler, H. (2003) NMR Chemical Shift Perturbation Study of the NTerminal Domain of Hsp90 upon Binding of ADP, AMP-PNP, Geldanamycin, and Radicicol. Chembiochem.,4, 870-877.
-
(2003)
Chembiochem.
, vol.4
, pp. 870-877
-
-
Dehner, A.1
Furrer, J.2
Richter, K.3
Schuster, I.4
Buchner, J.5
Kessler, H.6
-
91
-
-
0036303385
-
Stimulation of the weak ATPase activity of human hsp90 by a client protein
-
McLaughlin, S. H., Smith, H. W., and Jackson, S. E. (2002) Stimulation of the weak ATPase activity of human hsp90 by a client protein. J. Mol. Biol.,315, 787-798.
-
(2002)
J. Mol. Biol.
, vol.315
, pp. 787-798
-
-
McLaughlin, S.H.1
Smith, H.W.2
Jackson, S.E.3
-
92
-
-
0036510722
-
Regulation of heat shock protein 90 ATPase activity by sequences in the carboxyl terminus
-
Owen, B. A., Sullivan, W. P., Felts, S. J., and Toft, D. O. (2002) Regulation of heat shock protein 90 ATPase activity by sequences in the carboxyl terminus. J. Biol. Chem.,277, 7086-7091.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7086-7091
-
-
Owen, B.A.1
Sullivan, W.P.2
Felts, S.J.3
Toft, D.O.4
-
93
-
-
0036510547
-
A Nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90.N-terminal nucleotide binding unmasks a C-terminal binding pocket
-
Soti, C., Racz, A., and Csermely, P. (2002) A Nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90. N-terminal nucleotide binding unmasks a C-terminal binding pocket. J. Biol. Chem.,277, 7066-7075.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7066-7075
-
-
Soti, C.1
Racz, A.2
Csermely, P.3
-
94
-
-
18544386399
-
Binding of ATP to heat shock protein 90: evidence for an ATPbinding site in the C-terminal domain
-
Garnier, C., Lafitte, D., Tsvetkov, P. O., Barbier, P., Leclerc-Devin, J., Millot, J. M., Briand, C., Makarov, A. A., Catelli, M. G., and Peyrot, V. (2002) Binding of ATP to heat shock protein 90: evidence for an ATPbinding site in the C-terminal domain. J. Biol. Chem.,277, 12208-12214.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12208-12214
-
-
Garnier, C.1
Lafitte, D.2
Tsvetkov, P.O.3
Barbier, P.4
Leclerc-Devin, J.5
Millot, J.M.6
Briand, C.7
Makarov, A.A.8
Catelli, M.G.9
Peyrot, V.10
-
95
-
-
0028940309
-
Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase.Implications for heat shock in vivo
-
Jakob, U., Lilie, H., Meyer, I., and Buchner, J. (1995) Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase. Implications for heat shock in vivo. J. Biol. Chem.,270, 7288-7294.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7288-7294
-
-
Jakob, U.1
Lilie, H.2
Meyer, I.3
Buchner, J.4
-
96
-
-
0035868281
-
Substrate-binding characteristics of proteins in the 90 kDa heat shock protein family
-
Nemoto, T. K., Ono, T., and Tanaka, K. (2001) Substrate-binding characteristics of proteins in the 90 kDa heat shock protein family. Biochem. J.,354, 663-670.
-
(2001)
Biochem. J.
, vol.354
, pp. 663-670
-
-
Nemoto, T.K.1
Ono, T.2
Tanaka, K.3
-
97
-
-
0034693228
-
Hsp90 chaperone activity requires the fulllength protein and interaction among its multiple domains
-
Johnson, B. D., Chadli, A., Felts, S. J., Bouhouche, I., Catelli, M. G., and Toft, D. O. (2000) Hsp90 chaperone activity requires the fulllength protein and interaction among its multiple domains. J. Biol. Chem.,275, 32499-32507.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32499-32507
-
-
Johnson, B.D.1
Chadli, A.2
Felts, S.J.3
Bouhouche, I.4
Catelli, M.G.5
Toft, D.O.6
-
98
-
-
0026778032
-
Hsp90 chaperones protein folding in vitro
-
Wiech, H., Buchner, J., Zimmermann, R., and Jakob, U. (1992) Hsp90 chaperones protein folding in vitro. Nature,358, 169-170.
-
(1992)
Nature
, vol.358
, pp. 169-170
-
-
Wiech, H.1
Buchner, J.2
Zimmermann, R.3
Jakob, U.4
-
99
-
-
0029847609
-
Effect of geldanamycin on the kinetics of chaperone-mediated renaturation of firefly luciferase in rabbit reticulocyte lysate
-
Thulasiraman, V. and Matts, R. L. (1996) Effect of geldanamycin on the kinetics of chaperone-mediated renaturation of firefly luciferase in rabbit reticulocyte lysate. Biochemistry,35, 13443-13450.
-
(1996)
Biochemistry
, vol.35
, pp. 13443-13450
-
-
Thulasiraman, V.1
Matts, R.L.2
-
100
-
-
0030862486
-
Vitro evidence that hsp90 contains two independent chaperone sites
-
Young, J. C., Schneider, C., and Hartl, F. U. (1997) In vitro evidence that hsp90 contains two independent chaperone sites. FEBS Lett.,418, 139-143.
-
(1997)
FEBS Lett.
, vol.418
, pp. 139-143
-
-
Young, J.C.1
Schneider, C.2
Hartl, F.U.3
-
101
-
-
0033573992
-
The charged region of Hsp90 modulates the function of the N-terminal domain
-
Scheibel, T., Siegmund, H. I., Jaenicke, R., Ganz, P., Lilie, H., and Buchner, J. (1999) The charged region of Hsp90 modulates the function of the N-terminal domain. Proc. Natl. Acad. Sci. U.S.A,96, 1297-1302.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 1297-1302
-
-
Scheibel, T.1
Siegmund, H.I.2
Jaenicke, R.3
Ganz, P.4
Lilie, H.5
Buchner, J.6
-
102
-
-
0030802135
-
Binding affinity of proteins to hsp90 correlates with both hydrophobicity and positive charges
-
Csermely, P., Miyata, Y., Soti, C., and Yahara, I. (1997) Binding affinity of proteins to hsp90 correlates with both hydrophobicity and positive charges. A surface plasmon resonance study. Life Sci.,61, 411-418.
-
(1997)
A surface plasmon resonance study. Life Sci.
, vol.61
, pp. 411-418
-
-
Csermely, P.1
Miyata, Y.2
Soti, C.3
Yahara, I.4
-
103
-
-
0026669310
-
The 90-kDa heat shock protein, HSP90, binds and protects casein kinase II from self-aggregation and enhances its kinase activity
-
Miyata, Y. and Yahara, I. (1992) The 90-kDa heat shock protein, HSP90, binds and protects casein kinase II from self-aggregation and enhances its kinase activity. J. Biol. Chem.,267, 7042-7047.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 7042-7047
-
-
Miyata, Y.1
Yahara, I.2
-
104
-
-
0029063877
-
Interaction between casein kinase II and the 90-kDa stress protein, HSP90
-
Miyata, Y. and Yahara, I. (1995) Interaction between casein kinase II and the 90-kDa stress protein, HSP90. Biochemistry,34, 8123-8129.
-
(1995)
Biochemistry
, vol.34
, pp. 8123-8129
-
-
Miyata, Y.1
Yahara, I.2
-
105
-
-
0030667932
-
Vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone
-
Nathan, D. F., Vos, M. H., and Lindquist, S. (1997) In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone. Proc. Natl. Acad. Sci. U.S.A,94, 12949-12956.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A
, vol.94
, pp. 12949-12956
-
-
Nathan, D.F.1
Vos, M.H.2
Lindquist, S.3
-
106
-
-
0037174940
-
Radicicolsensitive peptide binding to the Nterminal portion of GRP94
-
Vogen, S., Gidalevitz, T., Biswas, C., Simen, B. B., Stein, E., Gulmen, F., and Argon, Y. (2002) Radicicolsensitive peptide binding to the Nterminal portion of GRP94. J. Biol. Chem.,277, 40742-40750.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40742-40750
-
-
Vogen, S.1
Gidalevitz, T.2
Biswas, C.3
Simen, B.B.4
Stein, E.5
Gulmen, F.6
Argon, Y.7
-
107
-
-
0031054687
-
Interaction of endoplasmic reticulum chaperone GRP94 with peptide substrates is adenine nucleotide-independent
-
Wearsch, P. A. and Nicchitta, C. V. (1997) Interaction of endoplasmic reticulum chaperone GRP94 with peptide substrates is adenine nucleotide-independent. J. Biol. Chem.,272, 5152-5156.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5152-5156
-
-
Wearsch, P.A.1
Nicchitta, C.V.2
-
108
-
-
0032554622
-
Structural transitions accompanying the activation of peptide binding to the endoplasmic reticulum Hsp90 chaperone GRP94
-
Wearsch, P. A., Voglino, L., and Nicchitta, C. V. (1998) Structural transitions accompanying the activation of peptide binding to the endoplasmic reticulum Hsp90 chaperone GRP94. Biochemistry,37, 5709-5719.
-
(1998)
Biochemistry
, vol.37
, pp. 5709-5719
-
-
Wearsch, P.A.1
Voglino, L.2
Nicchitta, C.V.3
-
109
-
-
1942469336
-
Identification of the N-terminal Peptide Binding Site of Glucoseregulated Protein 94
-
Gidalevitz, T., Biswas, C., Ding, H., Schneidman-Duhovny, D., Wolfson, H. J., Stevens, F., Radford, S., and Argon, Y. (2004) Identification of the N-terminal Peptide Binding Site of Glucoseregulated Protein 94. J. Biol. Chem.,279, 16543-16552.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16543-16552
-
-
Gidalevitz, T.1
Biswas, C.2
Ding, H.3
Schneidman-Duhovny, D.4
Wolfson, H.J.5
Stevens, F.6
Radford, S.7
Argon, Y.8
-
110
-
-
0242318392
-
High affinity binding of Hsp90 is triggered by multiple discrete segments of its kinase clients
-
Scroggins, B. T., Prince, T., Shao, J., Uma, S., Huang, W., Guo, Y., Yun, B. G., Hedman, K., Matts, R. L., and Hartson, S. D. (2003) High affinity binding of Hsp90 is triggered by multiple discrete segments of its kinase clients. Biochemistry,42, 12550-12561.
-
(2003)
Biochemistry
, vol.42
, pp. 12550-12561
-
-
Scroggins, B.T.1
Prince, T.2
Shao, J.3
Uma, S.4
Huang, W.5
Guo, Y.6
Yun, B.G.7
Hedman, K.8
Matts, R.L.9
Hartson, S.D.10
-
111
-
-
0027980828
-
Structural and functional aspects of basic helix-loop-helix protein folding by heat-shock protein 90
-
Shue, G. and Kohtz, D. S. (1994) Structural and functional aspects of basic helix-loop-helix protein folding by heat-shock protein 90. J. Biol. Chem.,269, 2707-2711.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2707-2711
-
-
Shue, G.1
Kohtz, D.S.2
-
112
-
-
0026722373
-
Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84)
-
Shaknovich, R., Shue, G., and Kohtz, D. S. (1992) Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84). Mol. Cell Biol.,12, 5059-5068.
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 5059-5068
-
-
Shaknovich, R.1
Shue, G.2
Kohtz, D.S.3
-
113
-
-
0036133258
-
Vitro reconstitution of functional hepadnavirus reverse transcriptase with cellular chaperone proteins
-
Hu, J., Toft, D., Anselmo, D., and Wang, X. (2002) In vitro reconstitution of functional hepadnavirus reverse transcriptase with cellular chaperone proteins. J. Virol.,76, 269-279.
-
(2002)
J. Virol.
, vol.76
, pp. 269-279
-
-
Hu, J.1
Toft, D.2
Anselmo, D.3
Wang, X.4
-
114
-
-
0141815723
-
Efficient Hsp90-independent in vitro activation by Hsc70 and Hsp40 of duck hepatits B virus reverse transcriptase, an assumed Hsp90 client protein
-
Beck, J. and Nassal, M. (2003). Efficient Hsp90-independent in vitro activation by Hsc70 and Hsp40 of duck hepatits B virus reverse transcriptase, an assumed Hsp90 client protein. J. Biol. Chem.
-
(2003)
J. Biol. Chem.
-
-
Beck, J.1
Nassal, M.2
-
115
-
-
0034329452
-
Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23
-
Young, J. C. and Hartl, F. U. (2000) Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23. EMBO J.,19, 5930-5940.
-
(2000)
EMBO J.
, vol.19
, pp. 5930-5940
-
-
Young, J.C.1
Hartl, F.U.2
-
116
-
-
0025644194
-
Structural and functional reconstitution of the glucocorticoid receptor-hsp90 complex
-
Scherrer, L. C., Dalman, F. C., Massa, E., Meshinchi, S., and Pratt, W. B. (1990) Structural and functional reconstitution of the glucocorticoid receptor-hsp90 complex. J. Biol. Chem.,265, 21397-21400.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 21397-21400
-
-
Scherrer, L.C.1
Dalman, F.C.2
Massa, E.3
Meshinchi, S.4
Pratt, W.B.5
-
117
-
-
0013913886
-
A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization
-
Toft, D. and Gorski, J. (1966) A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization. Proc. Natl. Acad. Sci. U.S.A,55, 1574-1581.
-
(1966)
Proc. Natl. Acad. Sci. U.S.A
, vol.55
, pp. 1574-1581
-
-
Toft, D.1
Gorski, J.2
-
118
-
-
0023622372
-
Demonstration that the 90-kilodalton heat shock protein is bound to the glucocorticoid receptor in its 9S nondeoxynucleic acid binding form
-
Sanchez, E. R., Meshinchi, S., Schlesinger, M. J., and Pratt, W. B. (1987) Demonstration that the 90-kilodalton heat shock protein is bound to the glucocorticoid receptor in its 9S nondeoxynucleic acid binding form. Mol. Endocrinol.,1, 908-912.
-
(1987)
Mol. Endocrinol.
, vol.1
, pp. 908-912
-
-
Sanchez, E.R.1
Meshinchi, S.2
Schlesinger, M.J.3
Pratt, W.B.4
-
119
-
-
0025640051
-
Reconstitution of progesterone receptor with heat shock proteins
-
Smith, D. F., Schowalter, D. B., Kost, S. L., and Toft, D. O. (1990) Reconstitution of progesterone receptor with heat shock proteins. Mol. Endocrinol.,4, 1704-1711.
-
(1990)
Mol. Endocrinol.
, vol.4
, pp. 1704-1711
-
-
Smith, D.F.1
Schowalter, D.B.2
Kost, S.L.3
Toft, D.O.4
-
120
-
-
0027484097
-
Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes
-
Smith, D. F. (1993) Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes. Mol. Endocrinol.,7, 1418-1429.
-
(1993)
Mol. Endocrinol.
, vol.7
, pp. 1418-1429
-
-
Smith, D.F.1
-
121
-
-
0027439595
-
Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70
-
Smith, D. F., Sullivan, W. P., Marion, T. N., Zaitsu, K., Madden, B., McCormick, D. J., and Toft, D. O. (1993) Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70. Mol. Cell Biol.,13, 869-876.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 869-876
-
-
Smith, D.F.1
Sullivan, W.P.2
Marion, T.N.3
Zaitsu, K.4
Madden, B.5
McCormick, D.J.6
Toft, D.O.7
-
122
-
-
0028266874
-
Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes
-
Johnson, J. L., Beito, T. G., Krco, C. J., and Toft, D. O. (1994) Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes. Mol. Cell Biol.,14, 1956-1963.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 1956-1963
-
-
Johnson, J.L.1
Beito, T.G.2
Krco, C.J.3
Toft, D.O.4
-
123
-
-
0029101382
-
The cyclosporin Abinding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor
-
Owens-Grillo, J. K., Hoffmann, K., Hutchison, K. A., Yem, A. W., Deibel, M. R., Jr., Handschumacher, R. E., and Pratt, W. B. (1995) The cyclosporin Abinding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor. J. Biol. Chem.,270, 20479-20484.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20479-20484
-
-
Owens-Grillo, J.K.1
Hoffmann, K.2
Hutchison, K.A.3
Yem, A.W.4
Deibel Jr., M.R.5
Handschumacher, R.E.6
Pratt, W.B.7
-
124
-
-
0027788244
-
Immunological identification of a 50 kDa Mr FK506-binding immunophilin as a component of the non-DNA binding, hsp90 and hsp70 containing, heterooligomeric form of the chick oviduct progesterone receptor
-
Renoir, J. M., Pahl, A., Keller, U., and Baulieu, E. E. (1993) Immunological identification of a 50 kDa Mr FK506-binding immunophilin as a component of the non-DNA binding, hsp90 and hsp70 containing, heterooligomeric form of the chick oviduct progesterone receptor. C. R. Acad. Sci. III,316, 1410-1416.
-
(1993)
C. R. Acad. Sci. III
, vol.316
, pp. 1410-1416
-
-
Renoir, J.M.1
Pahl, A.2
Keller, U.3
Baulieu, E.E.4
-
125
-
-
0027219348
-
Two FKBP-related proteins are associated with progesterone receptor complexes
-
Smith, D. F., Baggenstoss, B. A., Marion, T. N., and Rimerman, R. A. (1993) Two FKBP-related proteins are associated with progesterone receptor complexes. J. Biol. Chem.,268, 18365-18371.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18365-18371
-
-
Smith, D.F.1
Baggenstoss, B.A.2
Marion, T.N.3
Rimerman, R.A.4
-
126
-
-
0027985148
-
Conservation of Hsp90 macromolecular complexes in Saccharomyces cerevisiae
-
Chang, H. C. and Lindquist, S. (1994) Conservation of Hsp90 macromolecular complexes in Saccharomyces cerevisiae. J. Biol. Chem.,269, 24983-24988.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24983-24988
-
-
Chang, H.C.1
Lindquist, S.2
-
127
-
-
0025815731
-
Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000
-
Perdew, G. H. and Whitelaw, M. L. (1991) Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000. J. Biol. Chem.,266, 6708-6713.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 6708-6713
-
-
Perdew, G.H.1
Whitelaw, M.L.2
-
128
-
-
0034005058
-
A role for the Hsp40 Ydj1 in repression of basal steroid receptor activity in yeast
-
Johnson, J. L. and Craig, E. A. (2000) A role for the Hsp40 Ydj1 in repression of basal steroid receptor activity in yeast. Mol. Cell Biol.,20, 3027-3036.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 3027-3036
-
-
Johnson, J.L.1
Craig, E.A.2
-
129
-
-
0029026540
-
Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways
-
Kimura, Y., Yahara, I., and Lindquist, S. (1995) Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways. Science,268, 1362-1365.
-
(1995)
Science
, vol.268
, pp. 1362-1365
-
-
Kimura, Y.1
Yahara, I.2
Lindquist, S.3
-
130
-
-
0029872081
-
The involvement of p23, hsp90, and immunophilins in the assembly of progesterone receptor complexes
-
Johnson, J., Corbisier, R., Stensgard, B., and Toft, D. (1996) The involvement of p23, hsp90, and immunophilins in the assembly of progesterone receptor complexes. J. Steroid Biochem. Mol. Biol.,56, 31-37.
-
(1996)
J. Steroid Biochem. Mol. Biol.
, vol.56
, pp. 31-37
-
-
Johnson, J.1
Corbisier, R.2
Stensgard, B.3
Toft, D.4
-
131
-
-
84889770148
-
Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle
-
manuscript submitted
-
Richter, K., Walter, S., and Buchner, J. (2004). Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle. manuscript submitted.
-
(2004)
-
-
Richter, K.1
Walter, S.2
Buchner, J.3
-
132
-
-
0033081968
-
Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones
-
Prodromou, C., Siligardi, G., O'Brien, R., Woolfson, D. N., Regan, L., Panaretou, B., Ladbury, J. E., Piper, P. W., and Pearl, L. H. (1999) Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones. EMBO J.,18, 754-762.
-
(1999)
EMBO J.
, vol.18
, pp. 754-762
-
-
Prodromou, C.1
Siligardi, G.2
O'Brien, R.3
Woolfson, D.N.4
Regan, L.5
Panaretou, B.6
Ladbury, J.E.7
Piper, P.W.8
Pearl, L.H.9
-
133
-
-
0037518202
-
Sti1 is a non-competitive inhibitor of the Hsp90 ATPase.Binding prevents the N-terminal dimerization reaction during the atpase cycle
-
Richter, K., Muschler, P., Hainzl, O., Reinstein, J., and Buchner, J. (2003) Sti1 is a non-competitive inhibitor of the Hsp90 ATPase. Binding prevents the N-terminal dimerization reaction during the atpase cycle. J. Biol. Chem.,278, 10328-10333.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10328-10333
-
-
Richter, K.1
Muschler, P.2
Hainzl, O.3
Reinstein, J.4
Buchner, J.5
-
134
-
-
0029075280
-
Binding of p23 and hsp90 during assembly with the progesterone receptor
-
Johnson, J. L. and Toft, D. O. (1995) Binding of p23 and hsp90 during assembly with the progesterone receptor. Mol. Endocrinol.,9, 670-678.
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 670-678
-
-
Johnson, J.L.1
Toft, D.O.2
-
135
-
-
0037195951
-
The influence of ATP and p23 on the conformation of hsp90
-
Sullivan, W. P., Owen, B. A., and Toft, D. O. (2002). The influence of ATP and p23 on the conformation of hsp90. J. Biol. Chem.
-
(2002)
J. Biol. Chem.
-
-
Sullivan, W.P.1
Owen, B.A.2
Toft, D.O.3
-
136
-
-
0036931438
-
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1
-
Panaretou, B., Siligardi, G., Meyer, P., Maloney, A., Sullivan, J. K., Singh, S., Millson, S. H., Clarke, P. A., Naaby-Hansen, S., Stein, R., Cramer, R., Mollapour, M., Workman, P., Piper, P. W., Pearl, L. H., and Prodromou, C. (2002) Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. Mol. Cell,10, 1307-1318.
-
(2002)
Mol. Cell
, vol.10
, pp. 1307-1318
-
-
Panaretou, B.1
Siligardi, G.2
Meyer, P.3
Maloney, A.4
Sullivan, J.K.5
Singh, S.6
Millson, S.H.7
Clarke, P.A.8
Naaby-Hansen, S.9
Stein, R.10
Cramer, R.11
Mollapour, M.12
Workman, P.13
Piper, P.W.14
Pearl, L.H.15
Prodromou, C.16
-
137
-
-
0037023732
-
HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor
-
Hernandez, M. P., Chadli, A., and Toft, D. O. (2002) HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor. J. Biol. Chem.,277, 11873-11881.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11873-11881
-
-
Hernandez, M.P.1
Chadli, A.2
Toft, D.O.3
-
138
-
-
0037830586
-
Sti1 is a novel activator of the Ssa proteins
-
Wegele, H., Haslbeck, M., Reinstein, J., and Buchner, J. (2003) Sti1 is a novel activator of the Ssa proteins. J. Biol. Chem,278, 25970-25976.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 25970-25976
-
-
Wegele, H.1
Haslbeck, M.2
Reinstein, J.3
Buchner, J.4
-
139
-
-
0035969958
-
Evidence for iterative ratcheting of receptor-bound hsp70 between its ATP and ADP conformations during assembly of glucocorticoid receptor.hsp90 heterocomplexes
-
Morishima, Y., Kanelakis, K. C., Murphy, P. J., Shewach, D. S., and Pratt, W. B. (2001) Evidence for iterative ratcheting of receptor-bound hsp70 between its ATP and ADP conformations during assembly of glucocorticoid receptor.hsp90 heterocomplexes. Biochemistry,40, 1109-1116.
-
(2001)
Biochemistry
, vol.40
, pp. 1109-1116
-
-
Morishima, Y.1
Kanelakis, K.C.2
Murphy, P.J.3
Shewach, D.S.4
Pratt, W.B.5
-
140
-
-
0034629150
-
The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system
-
Morishima, Y., Kanelakis, K. C., Silverstein, A. M., Dittmar, K. D., Estrada, L., and Pratt, W. B. (2000) The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system. J. Biol. Chem.,275, 6894-6900.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6894-6900
-
-
Morishima, Y.1
Kanelakis, K.C.2
Silverstein, A.M.3
Dittmar, K.D.4
Estrada, L.5
Pratt, W.B.6
-
141
-
-
0032473425
-
The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPRmediated protein-protein interactions
-
Das, A. K., Cohen, P. W., and Barford, D. (1998) The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPRmediated protein-protein interactions. EMBO J.,17, 1192-1199.
-
(1998)
EMBO J.
, vol.17
, pp. 1192-1199
-
-
Das, A.K.1
Cohen, P.W.2
Barford, D.3
-
142
-
-
0037205411
-
Ligand discrimination by TPR domains.Relevance and selectivity of EEVDrecognition in Hsp70 X Hop X Hsp90 complexes
-
Brinker, A., Scheufler, C., Von Der, M. F., Fleckenstein, B., Herrmann, C., Jung, G., Moarefi, I., and Hartl, F. U. (2002) Ligand discrimination by TPR domains. Relevance and selectivity of EEVDrecognition in Hsp70 X Hop X Hsp90 complexes. J. Biol. Chem.,277, 19265-19275.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19265-19275
-
-
Brinker, A.1
Scheufler, C.2
Von Der, M.F.3
Fleckenstein, B.4
Herrmann, C.5
Jung, G.6
Moarefi, I.7
Hartl, F.U.8
-
143
-
-
0037470073
-
Tetratricopeptide repeat motif-mediated Hsc70-mSTI1 interaction. Molecular characterization of the critical contacts for successful binding and specificity
-
Odunuga, O. O., Hornby, J. A., Bies, C., Zimmermann, R., Pugh, D. J., and Blatch, G. L. (2003) Tetratricopeptide repeat motif-mediated Hsc70-mSTI1 interaction. Molecular characterization of the critical contacts for successful binding and specificity. J. Biol. Chem.,278, 6896-6904.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6896-6904
-
-
Odunuga, O.O.1
Hornby, J.A.2
Bies, C.3
Zimmermann, R.4
Pugh, D.J.5
Blatch, G.L.6
-
144
-
-
0028027504
-
A novel chaperone complex for steroid receptors involving heat shock proteins, immunophilins, and p23
-
Johnson, J. L. and Toft, D. O. (1994) A novel chaperone complex for steroid receptors involving heat shock proteins, immunophilins, and p23. J. Biol. Chem.,269, 24989-24993.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24989-24993
-
-
Johnson, J.L.1
Toft, D.O.2
-
145
-
-
0032760261
-
An unstructured C-terminal region of the Hsp90 cochaperone p23 is important for its chaperone function
-
Weikl, T., Abelmann, K., and Buchner, J. (1999) An unstructured C-terminal region of the Hsp90 cochaperone p23 is important for its chaperone function. J. Mol. Biol.,293, 685-691.
-
(1999)
J. Mol. Biol.
, vol.293
, pp. 685-691
-
-
Weikl, T.1
Abelmann, K.2
Buchner, J.3
-
146
-
-
0034725641
-
Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone
-
Weaver, A. J., Sullivan, W. P., Felts, S. J., Owen, B. A., and Toft, D. O. (2000) Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone. J. Biol. Chem.,275, 23045-23052.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23045-23052
-
-
Weaver, A.J.1
Sullivan, W.P.2
Felts, S.J.3
Owen, B.A.4
Toft, D.O.5
-
147
-
-
0034602390
-
Cpr6 and Cpr7, two closely related Hsp90-associated immunophilins from Saccharomyces cerevisiae, differ in their functional properties
-
Mayr, C., Richter, K., Lilie, H., and Buchner, J. (2000) Cpr6 and Cpr7, two closely related Hsp90-associated immunophilins from Saccharomyces cerevisiae, differ in their functional properties. J. Biol. Chem.,275, 34140-34146.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34140-34146
-
-
Mayr, C.1
Richter, K.2
Lilie, H.3
Buchner, J.4
-
148
-
-
0034968225
-
Functional analysis of the Hsp90-associated human peptidyl prolyl cis/ trans isomerases FKBP51, FKBP52 and Cyp40
-
Pirkl, F. and Buchner, J. (2001) Functional analysis of the Hsp90-associated human peptidyl prolyl cis/ trans isomerases FKBP51, FKBP52 and Cyp40. J. Mol. Biol.,308, 795-806.
-
(2001)
J. Mol. Biol.
, vol.308
, pp. 795-806
-
-
Pirkl, F.1
Buchner, J.2
-
149
-
-
1942437504
-
Multiple Domains of the Co-chaperone Hop Are Important for Hsp70 Binding
-
Carrigan, P. E., Nelson, G. M., Roberts, P. J., Stoffer, J., Riggs, D. L., and Smith, D. F. (2004) Multiple Domains of the Co-chaperone Hop Are Important for Hsp70 Binding. J. Biol. Chem.,279, 16185-16193.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16185-16193
-
-
Carrigan, P.E.1
Nelson, G.M.2
Roberts, P.J.3
Stoffer, J.4
Riggs, D.L.5
Smith, D.F.6
-
150
-
-
0038269022
-
C-terminal sequences outside the tetratricopeptide repeat domain of FKBP51 and FKBP52 cause differential binding to Hsp90
-
Cheung-Flynn, J., Roberts, P. J., Riggs, D. L., and Smith, D. F. (2003) C-terminal sequences outside the tetratricopeptide repeat domain of FKBP51 and FKBP52 cause differential binding to Hsp90. J. Biol. Chem.,278, 17388-17394.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17388-17394
-
-
Cheung-Flynn, J.1
Roberts, P.J.2
Riggs, D.L.3
Smith, D.F.4
-
151
-
-
0031053574
-
Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor
-
Nair, S. C., Rimerman, R. A., Toran, E. J., Chen, S., Prapapanich, V., Butts, R. N., and Smith, D. F. (1997) Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor. Mol. Cell Biol.,17, 594-603.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 594-603
-
-
Nair, S.C.1
Rimerman, R.A.2
Toran, E.J.3
Chen, S.4
Prapapanich, V.5
Butts, R.N.6
Smith, D.F.7
-
152
-
-
0032079539
-
The peptidylprolyl isomerase domain of the CyP-40 cyclophilin homolog Cpr7 is not required to support growth or glucocorticoid receptor activity in Saccharomyces cerevisiae
-
Duina, A. A., Marsh, J. A., Kurtz, R. B., Chang, H. C., Lindquist, S., and Gaber, R. F. (1998) The peptidylprolyl isomerase domain of the CyP-40 cyclophilin homolog Cpr7 is not required to support growth or glucocorticoid receptor activity in Saccharomyces cerevisiae. J. Biol. Chem.,273, 10819-10822.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10819-10822
-
-
Duina, A.A.1
Marsh, J.A.2
Kurtz, R.B.3
Chang, H.C.4
Lindquist, S.5
Gaber, R.F.6
-
153
-
-
0029852803
-
Chaperone function of Hsp90-associated proteins
-
Bose, S., Weikl, T., Bugl, H., and Buchner, J. (1996) Chaperone function of Hsp90-associated proteins. Science,274, 1715-1717.
-
(1996)
Science
, vol.274
, pp. 1715-1717
-
-
Bose, S.1
Weikl, T.2
Bugl, H.3
Buchner, J.4
-
154
-
-
0035813134
-
Localization of the chaperone domain of FKBP52
-
Pirkl, F., Fischer, E., Modrow, S., and Buchner, J. (2001) Localization of the chaperone domain of FKBP52. J. Biol. Chem.,276, 37034-37041.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37034-37041
-
-
Pirkl, F.1
Fischer, E.2
Modrow, S.3
Buchner, J.4
-
155
-
-
0033499798
-
Multiple components of the HSP90 chaperone complex function in regulation of heat shock factor 1 vivo
-
Bharadwaj, S., Ali, A., and Ovsenek, N. (1999) Multiple components of the HSP90 chaperone complex function in regulation of heat shock factor 1 In vivo. Mol. Cell Biol.,19, 8033-8041.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 8033-8041
-
-
Bharadwaj, S.1
Ali, A.2
Ovsenek, N.3
-
156
-
-
0033601331
-
Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein
-
Silverstein, A. M., Galigniana, M. D., Kanelakis, K. C., Radanyi, C., Renoir, J. M., and Pratt, W. B. (1999) Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein. J. Biol. Chem.,274, 36980-36986.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36980-36986
-
-
Silverstein, A.M.1
Galigniana, M.D.2
Kanelakis, K.C.3
Radanyi, C.4
Renoir, J.M.5
Pratt, W.B.6
-
157
-
-
0035805599
-
Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus
-
Galigniana, M. D., Radanyi, C., Renoir, J. M., Housley, P. R., and Pratt, W. B. (2001) Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus. J. Biol. Chem.,276, 14884-14889.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14884-14889
-
-
Galigniana, M.D.1
Radanyi, C.2
Renoir, J.M.3
Housley, P.R.4
Pratt, W.B.5
-
158
-
-
0037085381
-
A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins
-
Davies, T. H., Ning, Y. M., and Sanchez, E. R. (2002) A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. J. Biol. Chem.,277, 4597-4600.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4597-4600
-
-
Davies, T.H.1
Ning, Y.M.2
Sanchez, E.R.3
-
159
-
-
2542482495
-
Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus
-
Galigniana, M. D., Harrell, J. M., O'Hagen, H. M., Ljungman, M., and Pratt, W. B. (2004). Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus. J. Biol. Chem.
-
(2004)
J. Biol. Chem.
-
-
Galigniana, M.D.1
Harrell, J.M.2
O'Hagen, H.M.3
Ljungman, M.4
Pratt, W.B.5
-
160
-
-
0037416154
-
The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo
-
Riggs, D. L., Roberts, P. J., Chirillo, S. C., Cheung-Flynn, J., Prapapanich, V., Ratajczak, T., Gaber, R., Picard, D., and Smith, D. F. (2003) The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo. EMBO J.,22, 1158-1167.
-
(2003)
EMBO J.
, vol.22
, pp. 1158-1167
-
-
Riggs, D.L.1
Roberts, P.J.2
Chirillo, S.C.3
Cheung-Flynn, J.4
Prapapanich, V.5
Ratajczak, T.6
Gaber, R.7
Picard, D.8
Smith, D.F.9
-
161
-
-
0030921056
-
Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin
-
Silverstein, A. M., Galigniana, M. D., Chen, M. S., Owens-Grillo, J. K., Chinkers, M., and Pratt, W. B. (1997) Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin. J. Biol. Chem.,272, 16224-16230.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16224-16230
-
-
Silverstein, A.M.1
Galigniana, M.D.2
Chen, M.S.3
Owens-Grillo, J.K.4
Chinkers, M.5
Pratt, W.B.6
-
162
-
-
0029665779
-
Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4
-
Stepanova, L., Leng, X., Parker, S. B., and Harper, J. W. (1996) Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4. Genes Dev.,10, 1491-1502.
-
(1996)
Genes Dev.
, vol.10
, pp. 1491-1502
-
-
Stepanova, L.1
Leng, X.2
Parker, S.B.3
Harper, J.W.4
-
163
-
-
0022574582
-
Interaction of the Rous sarcoma virus protein pp60src with the cellular proteins pp50 and pp90
-
Brugge, J. S. (1986) Interaction of the Rous sarcoma virus protein pp60src with the cellular proteins pp50 and pp90. Curr. Top. Microbiol. Immunol.,123, 1-22.
-
(1986)
Curr. Top. Microbiol. Immunol.
, vol.123
, pp. 1-22
-
-
Brugge, J.S.1
-
164
-
-
0033055908
-
P50(cdc37) acting in concert with Hsp90 is required for Raf-1 function
-
Grammatikakis, N., Lin, J. H., Grammatikakis, A., Tsichlis, P. N., and Cochran, B. H. (1999) p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function. Mol. Cell Biol.,19, 1661-1672.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 1661-1672
-
-
Grammatikakis, N.1
Lin, J.H.2
Grammatikakis, A.3
Tsichlis, P.N.4
Cochran, B.H.5
-
165
-
-
0032814144
-
Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization
-
Stewart, S., Sundaram, M., Zhang, Y., Lee, J., Han, M., and Guan, K. L. (1999) Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization. Mol. Cell Biol.,19, 5523-5534.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 5523-5534
-
-
Stewart, S.1
Sundaram, M.2
Zhang, Y.3
Lee, J.4
Han, M.5
Guan, K.L.6
-
166
-
-
0042092020
-
Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase
-
Tatebe, H. and Shiozaki, K. (2003) Identification of Cdc37 as a novel regulator of the stress-responsive mitogen-activated protein kinase. Mol. Cell Biol.,23, 5132-5142.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 5132-5142
-
-
Tatebe, H.1
Shiozaki, K.2
-
167
-
-
0033524442
-
Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90
-
Xu, Y., Singer, M. A., and Lindquist, S. (1999) Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90. Proc. Natl. Acad. Sci. U.S.A,96, 109-114.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 109-114
-
-
Xu, Y.1
Singer, M.A.2
Lindquist, S.3
-
168
-
-
0027291238
-
Heat-shock protein hsp90 governs the activity of pp60v-src kinase
-
Xu, Y. and Lindquist, S. (1993) Heat-shock protein hsp90 governs the activity of pp60v-src kinase. Proc. Natl. Acad. Sci. U.S.A,90, 7074-7078.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A
, vol.90
, pp. 7074-7078
-
-
Xu, Y.1
Lindquist, S.2
-
169
-
-
0030998294
-
Interaction between Cdc37 and Cdk4 in human cells
-
Lamphere, L., Fiore, F., Xu, X., Brizuela, L., Keezer, S., Sardet, C., Draetta, G. F., and Gyuris, J. (1997) Interaction between Cdc37 and Cdk4 in human cells. Oncogene,14, 1999-2004.
-
(1997)
Oncogene
, vol.14
, pp. 1999-2004
-
-
Lamphere, L.1
Fiore, F.2
Xu, X.3
Brizuela, L.4
Keezer, S.5
Sardet, C.6
Draetta, G.F.7
Gyuris, J.8
-
170
-
-
0030935063
-
A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37
-
Perdew, G. H., Wiegand, H., Vanden Heuvel, J. P., Mitchell, C., and Singh, S. S. (1997) A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37. Biochemistry,36, 3600-3607.
-
(1997)
Biochemistry
, vol.36
, pp. 3600-3607
-
-
Perdew, G.H.1
Wiegand, H.2
Vanden Heuvel, J.P.3
Mitchell, C.4
Singh, S.S.5
-
171
-
-
0037036458
-
Regulation of Hsp90 ATPase activity by the cochaperone Cdc37p/p50cdc37
-
Siligardi, G., Panaretou, B., Meyer, P., Singh, S., Woolfson, D. N., Piper, P. W., Pearl, L. H., and Prodromou, C. (2002) Regulation of Hsp90 ATPase activity by the cochaperone Cdc37p/p50cdc37. J. Biol. Chem,277, 20151-20159.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 20151-20159
-
-
Siligardi, G.1
Panaretou, B.2
Meyer, P.3
Singh, S.4
Woolfson, D.N.5
Piper, P.W.6
Pearl, L.H.7
Prodromou, C.8
-
172
-
-
0742269688
-
The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37)
-
Roe, S. M., Ali, M. M., Meyer, P., Vaughan, C. K., Panaretou, B., Piper, P. W., Prodromou, C., and Pearl, L. H. (2004) The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37). Cell,116, 87-98.
-
(2004)
Cell
, vol.116
, pp. 87-98
-
-
Roe, S.M.1
Ali, M.M.2
Meyer, P.3
Vaughan, C.K.4
Panaretou, B.5
Piper, P.W.6
Prodromou, C.7
Pearl, L.H.8
-
173
-
-
1642505452
-
Sti1 and Cdc37 can stabilize Hsp90 in chaperone complexes with a protein kinase
-
Lee, P., Shabbir, A., Cardozo, C., and Caplan, A. J. (2004) Sti1 and Cdc37 can stabilize Hsp90 in chaperone complexes with a protein kinase. Mol. Biol. Cell,15, 1785-1792.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1785-1792
-
-
Lee, P.1
Shabbir, A.2
Cardozo, C.3
Caplan, A.J.4
-
175
-
-
0036754939
-
The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically
-
Abbas-Terki, T., Briand, P. A., Donze, O., and Picard, D. (2002) The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically. Biol. Chem,383, 1335-1342.
-
(2002)
Biol. Chem
, vol.383
, pp. 1335-1342
-
-
Abbas-Terki, T.1
Briand, P.A.2
Donze, O.3
Picard, D.4
-
176
-
-
0030745769
-
Cdc37 is a molecular chaperone with specific functions in signal transduction
-
Kimura, Y., Rutherford, S. L., Miyata, Y., Yahara, I., Freeman, B. C., Yue, L., Morimoto, R. I., and Lindquist, S. (1997) Cdc37 is a molecular chaperone with specific functions in signal transduction. Genes Dev.,11, 1775-1785.
-
(1997)
Genes Dev.
, vol.11
, pp. 1775-1785
-
-
Kimura, Y.1
Rutherford, S.L.2
Miyata, Y.3
Yahara, I.4
Freeman, B.C.5
Yue, L.6
Morimoto, R.I.7
Lindquist, S.8
-
177
-
-
0037428164
-
Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70
-
Young, J. C., Hoogenraad, N. J., and Hartl, F. U. (2003) Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70. Cell,112, 41-50.
-
(2003)
Cell
, vol.112
, pp. 41-50
-
-
Young, J.C.1
Hoogenraad, N.J.2
Hartl, F.U.3
-
178
-
-
0642377466
-
More than folding: localized functions of cytosolic chaperones
-
Young, J. C., Barral, J. M., and Ulrich, H. F. (2003) More than folding: localized functions of cytosolic chaperones. Trends Biochem. Sci.,28, 541-547.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 541-547
-
-
Young, J.C.1
Barral, J.M.2
Ulrich, H.F.3
-
179
-
-
0033013126
-
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions
-
Ballinger, C. A., Connell, P., Wu, Y., Hu, Z., Thompson, L. J., Yin, L. Y., and Patterson, C. (1999) Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions. Mol. Cell Biol.,19, 4535-4545.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 4535-4545
-
-
Ballinger, C.A.1
Connell, P.2
Wu, Y.3
Hu, Z.4
Thompson, L.J.5
Yin, L.Y.6
Patterson, C.7
-
180
-
-
0035684430
-
CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein
-
Murata, S., Minami, Y., Minami, M., Chiba, T., and Tanaka, K. (2001) CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein. EMBO Rep.,2, 1133-1138.
-
(2001)
EMBO Rep.
, vol.2
, pp. 1133-1138
-
-
Murata, S.1
Minami, Y.2
Minami, M.3
Chiba, T.4
Tanaka, K.5
-
181
-
-
0033166694
-
SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex
-
Kitagawa, K., Skowyra, D., Elledge, S. J., Harper, J. W., and Hieter, P. (1999) SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. Mol. Cell,4, 21-33.
-
(1999)
Mol. Cell
, vol.4
, pp. 21-33
-
-
Kitagawa, K.1
Skowyra, D.2
Elledge, S.J.3
Harper, J.W.4
Hieter, P.5
-
182
-
-
0141705339
-
HSP90 interacts with RAR1 and SGT1 and is essential for RPS2-mediated disease resistance in Arabidopsis
-
Takahashi, A., Casais, C., Ichimura, K., and Shirasu, K. (2003) HSP90 interacts with RAR1 and SGT1 and is essential for RPS2-mediated disease resistance in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A,100, 11777-11782.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 11777-11782
-
-
Takahashi, A.1
Casais, C.2
Ichimura, K.3
Shirasu, K.4
-
183
-
-
0347087451
-
Molecular chaperone Hsp90 associates with resistance protein N and its signaling proteins SGT1 and Rar1 to modulate an innate immune response in plants
-
Liu, Y., Burch-Smith, T., Schiff, M., Feng, S., and Dinesh-Kumar, S. P. (2004) Molecular chaperone Hsp90 associates with resistance protein N and its signaling proteins SGT1 and Rar1 to modulate an innate immune response in plants. J. Biol. Chem.,279, 2101-2108.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2101-2108
-
-
Liu, Y.1
Burch-Smith, T.2
Schiff, M.3
Feng, S.4
Dinesh-Kumar, S.P.5
-
184
-
-
0037086347
-
Regulatory role of SGT1 in early R gene-mediated plant defenses
-
Austin, M. J., Muskett, P., Kahn, K., Feys, B. J., Jones, J. D., and Parker, J. E. (2002) Regulatory role of SGT1 in early R gene-mediated plant defenses. Science,295, 2077-2080.
-
(2002)
Science
, vol.295
, pp. 2077-2080
-
-
Austin, M.J.1
Muskett, P.2
Kahn, K.3
Feys, B.J.4
Jones, J.D.5
Parker, J.E.6
-
185
-
-
0037048699
-
P23 and HSP20/alpha-crystallin proteins define a conserved sequence domain present in other eukaryotic protein families
-
Garcia-Ranea, J. A., Mirey, G., Camonis, J., and Valencia, A. (2002) p23 and HSP20/alpha-crystallin proteins define a conserved sequence domain present in other eukaryotic protein families. FEBS Lett.,529, 162-167.
-
(2002)
FEBS Lett.
, vol.529
, pp. 162-167
-
-
Garcia-Ranea, J.A.1
Mirey, G.2
Camonis, J.3
Valencia, A.4
-
186
-
-
1942436961
-
Human Sgt1 Binds HSP90 through the CHORDSgt1 Domain and Not the Tetratricopeptide Repeat Domain
-
Lee, Y. T., Jacob, J., Michowski, W., Nowotny, M., Kuznicki, J., and Chazin, W. J. (2004) Human Sgt1 Binds HSP90 through the CHORDSgt1 Domain and Not the Tetratricopeptide Repeat Domain. J. Biol. Chem.,279, 16511-16517.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16511-16517
-
-
Lee, Y.T.1
Jacob, J.2
Michowski, W.3
Nowotny, M.4
Kuznicki, J.5
Chazin, W.J.6
-
187
-
-
0033574059
-
Identification of SSF1, CNS1, and HCH1 as multicopy suppressors of a Saccharomyces cerevisiae Hsp90 loss-of-function mutation
-
Nathan, D. F., Vos, M. H., and Lindquist, S. (1999) Identification of SSF1, CNS1, and HCH1 as multicopy suppressors of a Saccharomyces cerevisiae Hsp90 loss-of-function mutation. Proc. Natl. Acad. Sci. U.S.A,96, 1409-1414.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 1409-1414
-
-
Nathan, D.F.1
Vos, M.H.2
Lindquist, S.3
-
188
-
-
10744221887
-
Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery
-
Meyer, P., Prodromou, C., Liao, C., Hu, B., Mark, R. S., Vaughan, C. K., Vlasic, I., Panaretou, B., Piper, P. W., and Pearl, L. H. (2004) Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery. EMBO J.,23, 511-519.
-
(2004)
EMBO J.
, vol.23
, pp. 511-519
-
-
Meyer, P.1
Prodromou, C.2
Liao, C.3
Hu, B.4
Mark, R.S.5
Vaughan, C.K.6
Vlasic, I.7
Panaretou, B.8
Piper, P.W.9
Pearl, L.H.10
-
189
-
-
0037593900
-
Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone
-
Lotz, G. P., Lin, H., Harst, A., and Obermann, W. M. (2003) Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone. J. Biol. Chem.,278, 17228-17235.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17228-17235
-
-
Lotz, G.P.1
Lin, H.2
Harst, A.3
Obermann, W.M.4
-
190
-
-
0031756340
-
CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90
-
Dolinski, K. J., Cardenas, M. E., and Heitman, J. (1998) CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90. Mol. Cell Biol.,18, 7344-7352.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 7344-7352
-
-
Dolinski, K.J.1
Cardenas, M.E.2
Heitman, J.3
-
191
-
-
0034957003
-
The Drosophila Dpit47 protein is a nuclear Hsp90 co-chaperone that interacts with DNA polymerase alpha
-
Crevel, G., Bates, H., Huikeshoven, H., and Cotterill, S. (2001) The Drosophila Dpit47 protein is a nuclear Hsp90 co-chaperone that interacts with DNA polymerase alpha. J. Cell Sci.,114, 2015-2025.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2015-2025
-
-
Crevel, G.1
Bates, H.2
Huikeshoven, H.3
Cotterill, S.4
-
192
-
-
2542453964
-
Cns1 is an activator of the Ssa1 ATPase activity
-
Hainzl, O., Wegele, H., Richter, K., and Buchner, J. (2004). Cns1 is an activator of the Ssa1 ATPase activity. J. Biol. Chem.
-
(2004)
J. Biol. Chem.
-
-
Hainzl, O.1
Wegele, H.2
Richter, K.3
Buchner, J.4
-
193
-
-
0031755018
-
Cns1 is an essential protein associated with the hsp90 chaperone complex in Saccharomyces cerevisiae that can restore cyclophilin 40-dependent functions in cpr7Delta cells
-
Marsh, J. A., Kalton, H. M., and Gaber, R. F. (1998) Cns1 is an essential protein associated with the hsp90 chaperone complex in Saccharomyces cerevisiae that can restore cyclophilin 40-dependent functions in cpr7Delta cells. Mol. Cell Biol.,18, 7353-7359.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 7353-7359
-
-
Marsh, J.A.1
Kalton, H.M.2
Gaber, R.F.3
-
194
-
-
0042357461
-
Functional Interactions between Hsp90 and the Co-chaperones Cns1 and Cpr7 in Saccharomyces cerevisiae
-
Tesic, M., Marsh, J. A., Cullinan, S. B., and Gaber, R. F. (2003) Functional Interactions between Hsp90 and the Co-chaperones Cns1 and Cpr7 in Saccharomyces cerevisiae. J. Biol. Chem,278, 32692-32701.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 32692-32701
-
-
Tesic, M.1
Marsh, J.A.2
Cullinan, S.B.3
Gaber, R.F.4
-
195
-
-
1642453873
-
Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes
-
Ramadoss, P., Petrulis, J. R., Hollingshead, B. D., Kusnadi, A., and Perdew, G. H. (2004) Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes. Biochemistry,43, 700-709.
-
(2004)
Biochemistry
, vol.43
, pp. 700-709
-
-
Ramadoss, P.1
Petrulis, J.R.2
Hollingshead, B.D.3
Kusnadi, A.4
Perdew, G.H.5
-
196
-
-
0033551511
-
Characterization of the AhRhsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization
-
Meyer, B. K. and Perdew, G. H. (1999) Characterization of the AhRhsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization. Biochemistry,38, 8907-8917.
-
(1999)
Biochemistry
, vol.38
, pp. 8907-8917
-
-
Meyer, B.K.1
Perdew, G.H.2
-
197
-
-
0141704410
-
Defining the role for XAP2 in stabilisation of the dioxin receptor
-
Lees, M. J., Peet, D. J., and Whitelaw, M. L. (2003). Defining the role for XAP2 in stabilisation of the dioxin receptor. J. Biol. Chem.
-
(2003)
J. Biol. Chem.
-
-
Lees, M.J.1
Peet, D.J.2
Whitelaw, M.L.3
-
198
-
-
0036665912
-
Small glutamine-rich protein/viral protein U-binding protein is a novel cochaperone that affects heat shock protein 70 activity
-
Angeletti, P. C., Walker, D., and Panganiban, A. T. (2002) Small glutamine-rich protein/viral protein U-binding protein is a novel cochaperone that affects heat shock protein 70 activity. Cell Stress. Chaperones.,7, 258-268.
-
(2002)
Cell Stress. Chaperones.
, vol.7
, pp. 258-268
-
-
Angeletti, P.C.1
Walker, D.2
Panganiban, A.T.3
-
199
-
-
0042815093
-
Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/ Hsp90 chaperone system
-
Brychzy, A., Rein, T., Winklhofer, K. F., Hartl, F. U., Young, J. C., and Obermann, W. M. (2003) Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/ Hsp90 chaperone system. EMBO J.,22, 3613-3623.
-
(2003)
EMBO J.
, vol.22
, pp. 3613-3623
-
-
Brychzy, A.1
Rein, T.2
Winklhofer, K.F.3
Hartl, F.U.4
Young, J.C.5
Obermann, W.M.6
-
200
-
-
0023484186
-
5-Fluoroorotic acid as a selective agent in yeast molecular genetics
-
Boeke, J. D., Trueheart, J., Natsoulis, G., and Fink, G. R. (1987) 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol.,154, 164-175.
-
(1987)
Methods Enzymol.
, vol.154
, pp. 164-175
-
-
Boeke, J.D.1
Trueheart, J.2
Natsoulis, G.3
Fink, G.R.4
-
201
-
-
0032703419
-
Contribution of N-and C-terminal domains to the function of Hsp90 in Saccharomyces cerevisiae
-
Scheibel, T., Weikl, T., Rimerman, R., Smith, D., Lindquist, S., and Buchner, J. (1999) Contribution of N-and C-terminal domains to the function of Hsp90 in Saccharomyces cerevisiae. Mol. Microbiol.,34, 701-713.
-
(1999)
Mol. Microbiol.
, vol.34
, pp. 701-713
-
-
Scheibel, T.1
Weikl, T.2
Rimerman, R.3
Smith, D.4
Lindquist, S.5
Buchner, J.6
-
202
-
-
0032538995
-
Vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis
-
Obermann, W. M., Sondermann, H., Russo, A. A., Pavletich, N. P., and Hartl, F. U. (1998) In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J. Cell Biol.,143, 901-910.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 901-910
-
-
Obermann, W.M.1
Sondermann, H.2
Russo, A.A.3
Pavletich, N.P.4
Hartl, F.U.5
-
203
-
-
0025175208
-
Reduced levels of hsp90 compromise steroid receptor action in vivo
-
Picard, D., Khursheed, B., Garabedian, M. J., Fortin, M. G., Lindquist, S., and Yamamoto, K. R. (1990) Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature,348, 166-168.
-
(1990)
Nature
, vol.348
, pp. 166-168
-
-
Picard, D.1
Khursheed, B.2
Garabedian, M.J.3
Fortin, M.G.4
Lindquist, S.5
Yamamoto, K.R.6
-
204
-
-
0027419771
-
The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs
-
Ali, J. A., Jackson, A. P., Howells, A. J., and Maxwell, A. (1993) The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs. Biochemistry,32, 2717-2724.
-
(1993)
Biochemistry
, vol.32
, pp. 2717-2724
-
-
Ali, J.A.1
Jackson, A.P.2
Howells, A.J.3
Maxwell, A.4
-
205
-
-
0018600707
-
An improved assay for nanomole amounts of inorganic phosphate
-
Lanzetta, P. A., Alvarez, L. J., Reinach, P. S., and Candia, O. A. (1979) An improved assay for nanomole amounts of inorganic phosphate. Anal. Biochem.,100, 95-97.
-
(1979)
Anal. Biochem.
, vol.100
, pp. 95-97
-
-
Lanzetta, P.A.1
Alvarez, L.J.2
Reinach, P.S.3
Candia, O.A.4
-
206
-
-
0017900277
-
ATP utilization by rep protein in the catalytic separation of DNA strands at a replicating fork
-
Kornberg, A., Scott, J. F., and Bertsch, L. L. (1978) ATP utilization by rep protein in the catalytic separation of DNA strands at a replicating fork. J. Biol. Chem.,253, 3298-3304.
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 3298-3304
-
-
Kornberg, A.1
Scott, J.F.2
Bertsch, L.L.3
-
207
-
-
0034102339
-
The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies
-
Freeman, B. C., Felts, S. J., Toft, D. O., and Yamamoto, K. R. (2000) The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies. Genes Dev.,14, 422-434.
-
(2000)
Genes Dev.
, vol.14
, pp. 422-434
-
-
Freeman, B.C.1
Felts, S.J.2
Toft, D.O.3
Yamamoto, K.R.4
-
208
-
-
0027286137
-
Surface plasmon resonance for detection and measurement of antibody-antigen affinity and kinetics
-
Malmqvist, M. (1993) Surface plasmon resonance for detection and measurement of antibody-antigen affinity and kinetics. Curr. Opin. Immunol.,5, 282-286.
-
(1993)
Curr. Opin. Immunol.
, vol.5
, pp. 282-286
-
-
Malmqvist, M.1
-
209
-
-
0028822007
-
Surface plasmon resonance and its use in biomolecular interaction analysis (BIA)
-
Szabo, A., Stolz, L., and Granzow, R. (1995) Surface plasmon resonance and its use in biomolecular interaction analysis (BIA). Curr. Opin. Struct. Biol.,5, 699-705.
-
(1995)
Curr. Opin. Struct. Biol.
, vol.5
, pp. 699-705
-
-
Szabo, A.1
Stolz, L.2
Granzow, R.3
-
211
-
-
0034980394
-
Two structures of cyclophilin 40: folding and fidelity in the TPR domains
-
Taylor, P., Dornan, J., Carrello, A., Minchin, R. F., Ratajczak, T., and Walkinshaw, M. D. (2001) Two structures of cyclophilin 40: folding and fidelity in the TPR domains. Structure. (Camb.),9, 431-438.
-
(2001)
Structure. (Camb.)
, vol.9
, pp. 431-438
-
-
Taylor, P.1
Dornan, J.2
Carrello, A.3
Minchin, R.F.4
Ratajczak, T.5
Walkinshaw, M.D.6
-
212
-
-
0021261383
-
Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones
-
Joab, I., Radanyi, C., Renoir, M., Buchou, T., Catelli, M. G., Binart, N., Mester, J., and Baulieu, E. E. (1984) Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones. Nature,308, 850-853.
-
(1984)
Nature
, vol.308
, pp. 850-853
-
-
Joab, I.1
Radanyi, C.2
Renoir, M.3
Buchou, T.4
Catelli, M.G.5
Binart, N.6
Mester, J.7
Baulieu, E.E.8
-
213
-
-
0026591729
-
Antiandrogens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation
-
Veldscholte, J., Berrevoets, C. A., Brinkmann, A. O., Grootegoed, J. A., and Mulder, E. (1992) Antiandrogens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation. Biochemistry,31, 2393-2399.
-
(1992)
Biochemistry
, vol.31
, pp. 2393-2399
-
-
Veldscholte, J.1
Berrevoets, C.A.2
Brinkmann, A.O.3
Grootegoed, J.A.4
Mulder, E.5
-
214
-
-
0023741595
-
Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor
-
Denis, M., Cuthill, S., Wikstrom, A. C., Poellinger, L., and Gustafsson, J. A. (1988) Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor. Biochem. Biophys. Res. Commun.,155, 801-807.
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.155
, pp. 801-807
-
-
Denis, M.1
Cuthill, S.2
Wikstrom, A.C.3
Poellinger, L.4
Gustafsson, J.A.5
-
215
-
-
0023742858
-
Association of the Ah receptor with the 90-kDa heat shock protein
-
Perdew, G. H. (1988) Association of the Ah receptor with the 90-kDa heat shock protein. J. Biol. Chem.,263, 13802-13805.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 13802-13805
-
-
Perdew, G.H.1
-
216
-
-
0042236405
-
Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital
-
Yoshinari, K., Kobayashi, K., Moore, R., Kawamoto, T., and Negishi, M. (2003) Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital. FEBS Lett.,548, 17-20.
-
(2003)
FEBS Lett.
, vol.548
, pp. 17-20
-
-
Yoshinari, K.1
Kobayashi, K.2
Moore, R.3
Kawamoto, T.4
Negishi, M.5
-
217
-
-
0034737291
-
Molecular chaperones activate the Drosophila ecdysone receptor, an RXR heterodimer
-
Arbeitman, M. N. and Hogness, D. S. (2000) Molecular chaperones activate the Drosophila ecdysone receptor, an RXR heterodimer. Cell,101, 67-77.
-
(2000)
Cell
, vol.101
, pp. 67-77
-
-
Arbeitman, M.N.1
Hogness, D.S.2
-
218
-
-
0024548918
-
Subunit composition of the estrogen receptor.Involvement of the hormone-binding domain in the dimeric state
-
Sabbah, M., Redeuilh, G., and Baulieu, E. E. (1989) Subunit composition of the estrogen receptor. Involvement of the hormone-binding domain in the dimeric state. J. Biol. Chem.,264, 2397-2400.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 2397-2400
-
-
Sabbah, M.1
Redeuilh, G.2
Baulieu, E.E.3
-
219
-
-
0024854466
-
Evidence that 5 S intermediate state in glucocorticoid receptor transformation contains hsp90 in addition to the steroidbinding protein
-
Ben Or, S. (1989) Evidence that 5 S intermediate state in glucocorticoid receptor transformation contains hsp90 in addition to the steroidbinding protein. J. Steroid Biochem.,33, 899-906.
-
(1989)
J. Steroid Biochem.
, vol.33
, pp. 899-906
-
-
Ben Or, S.1
-
220
-
-
0031806619
-
Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1
-
Zhang, L., Hach, A., and Wang, C. (1998) Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1. Mol. Cell Biol.,18, 3819-3828.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 3819-3828
-
-
Zhang, L.1
Hach, A.2
Wang, C.3
-
221
-
-
0031866191
-
HSP90 interacts with and regulates the activity of heat shock factor 1 in Xenopus oocytes
-
Ali, A., Bharadwaj, S., O'Carroll, R., and Ovsenek, N. (1998) HSP90 interacts with and regulates the activity of heat shock factor 1 in Xenopus oocytes. Mol. Cell Biol.,18, 4949-4960.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 4949-4960
-
-
Ali, A.1
Bharadwaj, S.2
O'Carroll, R.3
Ovsenek, N.4
-
222
-
-
0032749463
-
Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction
-
Minet, E., Mottet, D., Michel, G., Roland, I., Raes, M., Remacle, J., and Michiels, C. (1999) Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction. FEBS Lett.,460, 251-256.
-
(1999)
FEBS Lett.
, vol.460
, pp. 251-256
-
-
Minet, E.1
Mottet, D.2
Michel, G.3
Roland, I.4
Raes, M.5
Remacle, J.6
Michiels, C.7
-
223
-
-
0024411065
-
Mineralocorticosteroid receptor of the chick intestine. Oligomeric structure and transformation
-
Rafestin-Oblin, M. E., Couette, B., Radanyi, C., Lombes, M., and Baulieu, E. E. (1989) Mineralocorticosteroid receptor of the chick intestine. Oligomeric structure and transformation. J. Biol. Chem.,264, 9304-9309.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 9304-9309
-
-
Rafestin-Oblin, M.E.1
Couette, B.2
Radanyi, C.3
Lombes, M.4
Baulieu, E.E.5
-
224
-
-
0033005390
-
Association of MTG8 (ETO/CDR), a leukemia-related protein, with serine/ threonine protein kinases and heat shock protein HSP90 in human hematopoietic cell lines
-
Komori, A., Sueoka, E., Fujiki, H., Ishii, M., and Kozu, T. (1999) Association of MTG8 (ETO/CDR), a leukemia-related protein, with serine/ threonine protein kinases and heat shock protein HSP90 in human hematopoietic cell lines. Jpn. J. Cancer Res.,90, 60-68.
-
(1999)
Jpn. J. Cancer Res.
, vol.90
, pp. 60-68
-
-
Komori, A.1
Sueoka, E.2
Fujiki, H.3
Ishii, M.4
Kozu, T.5
-
225
-
-
0042318859
-
Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferatoractivated receptor-alpha (PPARalpha) and PPARbeta activity
-
Sumanasekera, W. K., Tien, E. S., Davis, J. W., Turpey, R., Perdew, G. H., and Vanden Heuvel, J. P. (2003) Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferatoractivated receptor-alpha (PPARalpha) and PPARbeta activity. Biochemistry,42, 10726-10735.
-
(2003)
Biochemistry
, vol.42
, pp. 10726-10735
-
-
Sumanasekera, W.K.1
Tien, E.S.2
Davis, J.W.3
Turpey, R.4
Perdew, G.H.5
Vanden Heuvel, J.P.6
-
226
-
-
0037799205
-
Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2
-
Sumanasekera, W. K., Tien, E. S., Turpey, R., Vanden Heuvel, J. P., and Perdew, G. H. (2003) Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2. J. Biol. Chem.,278, 4467-4473.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4467-4473
-
-
Sumanasekera, W.K.1
Tien, E.S.2
Turpey, R.3
Vanden Heuvel, J.P.4
Perdew, G.H.5
-
227
-
-
0022335385
-
The common 90-kd protein component of non-transformed '8S' steroid receptors is a heat-shock protein
-
Catelli, M. G., Binart, N., Jung-Testas, I., Renoir, J. M., Baulieu, E. E., Feramisco, J. R., and Welch, W. J. (1985) The common 90-kd protein component of non-transformed '8S' steroid receptors is a heat-shock protein. EMBO J.,4, 3131-3135.
-
(1985)
EMBO J.
, vol.4
, pp. 3131-3135
-
-
Catelli, M.G.1
Binart, N.2
Jung-Testas, I.3
Renoir, J.M.4
Baulieu, E.E.5
Feramisco, J.R.6
Welch, W.J.7
-
228
-
-
0022412314
-
A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src
-
Schuh, S., Yonemoto, W., Brugge, J., Bauer, V. J., Riehl, R. M., Sullivan, W. P., and Toft, D. O. (1985) A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src. J. Biol. Chem.,260, 14292-14296.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 14292-14296
-
-
Schuh, S.1
Yonemoto, W.2
Brugge, J.3
Bauer, V.J.4
Riehl, R.M.5
Sullivan, W.P.6
Toft, D.O.7
-
229
-
-
0028892084
-
A role for Hsp90 in retinoid receptor signal transduction
-
Holley, S. J. and Yamamoto, K. R. (1995) A role for Hsp90 in retinoid receptor signal transduction. Mol. Biol. Cell,6, 1833-1842.
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 1833-1842
-
-
Holley, S.J.1
Yamamoto, K.R.2
-
230
-
-
0029611034
-
The basic helix-loop-helix/PAS factor Sim is associated with hsp90.Implications for regulation by interaction with partner factors
-
McGuire, J., Coumailleau, P., Whitelaw, M. L., Gustafsson, J. A., and Poellinger, L. (1995) The basic helix-loop-helix/PAS factor Sim is associated with hsp90. Implications for regulation by interaction with partner factors. J. Biol. Chem.,270, 31353-31357.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 31353-31357
-
-
McGuire, J.1
Coumailleau, P.2
Whitelaw, M.L.3
Gustafsson, J.A.4
Poellinger, L.5
-
231
-
-
0037160084
-
Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes: preservation of cytokine signaling during fever
-
Shah, M., Patel, K., Fried, V. A., and Sehgal, P. B. (2002). Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes: preservation of cytokine signaling during fever. J. Biol. Chem.
-
(2002)
J. Biol. Chem.
-
-
Shah, M.1
Patel, K.2
Fried, V.A.3
Sehgal, P.B.4
-
232
-
-
0034624705
-
P53-independent association between SV40 large T antigen and the major cytosolic heat shock protein, HSP90
-
Miyata, Y. and Yahara, I. (2000) p53-independent association between SV40 large T antigen and the major cytosolic heat shock protein, HSP90. Oncogene,19, 1477-1484.
-
(2000)
Oncogene
, vol.19
, pp. 1477-1484
-
-
Miyata, Y.1
Yahara, I.2
-
233
-
-
0025847387
-
Cytosolic-nuclear tumor promoterspecific binding protein: association with the 90 kDa heat shock protein and translocation into nuclei by treatment with 12-O-tetradecanoylphorbol 13-acetate
-
Hashimoto, Y. and Shudo, K. (1991) Cytosolic-nuclear tumor promoterspecific binding protein: association with the 90 kDa heat shock protein and translocation into nuclei by treatment with 12-O-tetradecanoylphorbol 13-acetate. Jpn. J. Cancer Res.,82, 665-675.
-
(1991)
Jpn. J. Cancer Res.
, vol.82
, pp. 665-675
-
-
Hashimoto, Y.1
Shudo, K.2
-
234
-
-
0025969252
-
A subpopulation of the v-erb A oncogene protein, a derivative of a thyroid hormone receptor, associates with heat shock protein 90
-
Privalsky, M. L. (1991) A subpopulation of the v-erb A oncogene protein, a derivative of a thyroid hormone receptor, associates with heat shock protein 90. J. Biol. Chem.,266, 1456-1462.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 1456-1462
-
-
Privalsky, M.L.1
-
235
-
-
0031895122
-
Hsp90-containing multiprotein complexes in the eukaryotic microbe Achlya
-
Brunt, S. A., Perdew, G. H., Toft, D. O., and Silver, J. C. (1998) Hsp90-containing multiprotein complexes in the eukaryotic microbe Achlya. Cell Stress. Chaperones.,3, 44-56.
-
(1998)
Cell Stress. Chaperones.
, vol.3
, pp. 44-56
-
-
Brunt, S.A.1
Perdew, G.H.2
Toft, D.O.3
Silver, J.C.4
-
236
-
-
0033118355
-
Functional requirement of p23 and Hsp90 in telomerase complexes
-
Holt, S. E., Aisner, D. L., Baur, J., Tesmer, V. M., Dy, M., Ouellette, M., Trager, J. B., Morin, G. B., Toft, D. O., Shay, J. W., Wright, W. E., and White, M. A. (1999) Functional requirement of p23 and Hsp90 in telomerase complexes. Genes Dev.,13, 817-826.
-
(1999)
Genes Dev.
, vol.13
, pp. 817-826
-
-
Holt, S.E.1
Aisner, D.L.2
Baur, J.3
Tesmer, V.M.4
Dy, M.5
Ouellette, M.6
Trager, J.B.7
Morin, G.B.8
Toft, D.O.9
Shay, J.W.10
Wright, W.E.11
White, M.A.12
-
237
-
-
0030035038
-
Hsp90 is required for the activity of a hepatitis B virus reverse transcriptase
-
Hu, J. and Seeger, C. (1996) Hsp90 is required for the activity of a hepatitis B virus reverse transcriptase. Proc. Natl. Acad. Sci. U.S.A,93, 1060-1064.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 1060-1064
-
-
Hu, J.1
Seeger, C.2
-
238
-
-
0037155901
-
Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1
-
Fujita, N., Sato, S., Ishida, A., and Tsuruo, T. (2002) Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1. J. Biol. Chem.,277, 10346-10353.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10346-10353
-
-
Fujita, N.1
Sato, S.2
Ishida, A.3
Tsuruo, T.4
-
239
-
-
0034718540
-
Modulation of Akt kinase activity by binding to Hsp90
-
Sato, S., Fujita, N., and Tsuruo, T. (2000) Modulation of Akt kinase activity by binding to Hsp90. Proc. Natl. Acad. Sci. U.S.A,97, 10832-10837.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 10832-10837
-
-
Sato, S.1
Fujita, N.2
Tsuruo, T.3
-
240
-
-
1942486312
-
CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone, Cdc37
-
Miyata, Y. and Nishida, E. (2004) CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone, Cdc37. Mol. Cell Biol.,24, 4065-4074.
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 4065-4074
-
-
Miyata, Y.1
Nishida, E.2
-
241
-
-
0027933536
-
Interaction of the calcium and calmodulin regulated eEF-2 kinase with heat shock protein 90
-
Palmquist, K., Riis, B., Nilsson, A., and Nygard, O. (1994) Interaction of the calcium and calmodulin regulated eEF-2 kinase with heat shock protein 90. FEBS Lett.,349, 239-242.
-
(1994)
FEBS Lett.
, vol.349
, pp. 239-242
-
-
Palmquist, K.1
Riis, B.2
Nilsson, A.3
Nygard, O.4
-
242
-
-
0032996456
-
Genetic interactions between Hsp90 and the Cdc2 mitotic machinery in the fission yeast Schizosaccharomyces pombe
-
Munoz, M. J. and Jimenez, J. (1999) Genetic interactions between Hsp90 and the Cdc2 mitotic machinery in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet.,261, 242-250.
-
(1999)
Mol. Gen. Genet.
, vol.261
, pp. 242-250
-
-
Munoz, M.J.1
Jimenez, J.2
-
243
-
-
0032485070
-
Active cdk6 complexes are predominantly nuclear and represent only a minority of the cdk6 in T cells
-
Mahony, D., Parry, D. A., and Lees, E. (1998) Active cdk6 complexes are predominantly nuclear and represent only a minority of the cdk6 in T cells. Oncogene,16, 603-611.
-
(1998)
Oncogene
, vol.16
, pp. 603-611
-
-
Mahony, D.1
Parry, D.A.2
Lees, E.3
-
244
-
-
0034614455
-
Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription
-
O'Keeffe, B., Fong, Y., Chen, D., Zhou, S., and Zhou, Q. (2000) Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription. J. Biol. Chem.,275, 279-287.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 279-287
-
-
O'Keeffe, B.1
Fong, Y.2
Chen, D.3
Zhou, S.4
Zhou, Q.5
-
245
-
-
0347993069
-
Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress
-
Arlander, S. J., Eapen, A. K., Vroman, B. T., McDonald, R. J., Toft, D. O., and Karnitz, L. M. (2003) Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress. J. Biol. Chem.,278, 52572-52577.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52572-52577
-
-
Arlander, S.J.1
Eapen, A.K.2
Vroman, B.T.3
McDonald, R.J.4
Toft, D.O.5
Karnitz, L.M.6
-
246
-
-
0034599722
-
Hsp90 is required for c-Mos activation and biphasic MAP kinase activation in Xenopus oocytes
-
Fisher, D. L., Mandart, E., and Doree, M. (2000) Hsp90 is required for c-Mos activation and biphasic MAP kinase activation in Xenopus oocytes. EMBO J.,19, 1516-1524.
-
(2000)
EMBO J.
, vol.19
, pp. 1516-1524
-
-
Fisher, D.L.1
Mandart, E.2
Doree, M.3
-
247
-
-
0031054517
-
The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase
-
Stancato, L. F., Silverstein, A. M., Owens-Grillo, J. K., Chow, Y. H., Jove, R., and Pratt, W. B. (1997) The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase. J. Biol. Chem.,272, 4013-4020.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4013-4020
-
-
Stancato, L.F.1
Silverstein, A.M.2
Owens-Grillo, J.K.3
Chow, Y.H.4
Jove, R.5
Pratt, W.B.6
-
248
-
-
0035793546
-
Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90
-
Xu, W., Mimnaugh, E., Rosser, M. F., Nicchitta, C., Marcu, M., Yarden, Y., and Neckers, L. (2001) Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90. J. Biol. Chem.,276, 3702-3708.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3702-3708
-
-
Xu, W.1
Mimnaugh, E.2
Rosser, M.F.3
Nicchitta, C.4
Marcu, M.5
Yarden, Y.6
Neckers, L.7
-
249
-
-
0036050018
-
Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors
-
Minami, Y., Kiyoi, H., Yamamoto, Y., Yamamoto, K., Ueda, R., Saito, H., and Naoe, T. (2002) Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors. Leukemia,16, 1535-1540.
-
(2002)
Leukemia
, vol.16
, pp. 1535-1540
-
-
Minami, Y.1
Kiyoi, H.2
Yamamoto, Y.3
Yamamoto, K.4
Ueda, R.5
Saito, H.6
Naoe, T.7
-
250
-
-
0037358192
-
Integrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGF
-
Masson-Gadais, B., Houle, F., Laferriere, J., and Huot, J. (2003) Integrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGF. Cell Stress. Chaperones.,8, 37-52.
-
(2003)
Cell Stress. Chaperones.
, vol.8
, pp. 37-52
-
-
Masson-Gadais, B.1
Houle, F.2
Laferriere, J.3
Huot, J.4
-
251
-
-
0345803950
-
G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation
-
Luo, J. and Benovic, J. L. (2003) G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation. J. Biol. Chem.,278, 50908-50914.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50908-50914
-
-
Luo, J.1
Benovic, J.L.2
-
252
-
-
0033811029
-
P50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck
-
Scholz, G., Hartson, S. D., Cartledge, K., Hall, N., Shao, J., Dunn, A. R., and Matts, R. L. (2000) p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck. Mol. Cell Biol.,20, 6984-6995.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 6984-6995
-
-
Scholz, G.1
Hartson, S.D.2
Cartledge, K.3
Hall, N.4
Shao, J.5
Dunn, A.R.6
Matts, R.L.7
-
253
-
-
0024468795
-
Evidence for the association of the heme-regulated eIF-2 alpha kinase with the 90-kDa heat shock protein in rabbit reticulocyte lysate in situ
-
Matts, R. L. and Hurst, R. (1989) Evidence for the association of the heme-regulated eIF-2 alpha kinase with the 90-kDa heat shock protein in rabbit reticulocyte lysate in situ. J. Biol. Chem.,264, 15542-15547.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 15542-15547
-
-
Matts, R.L.1
Hurst, R.2
-
254
-
-
0023661048
-
The 90-kilodalton peptide of the hemeregulated eIF-2 alpha kinase has sequence similarity with the 90-kilodalton heat shock protein
-
Rose, D. W., Wettenhall, R. E., Kudlicki, W., Kramer, G., and Hardesty, B. (1987) The 90-kilodalton peptide of the hemeregulated eIF-2 alpha kinase has sequence similarity with the 90-kilodalton heat shock protein. Biochemistry,26, 6583-6587.
-
(1987)
Biochemistry
, vol.26
, pp. 6583-6587
-
-
Rose, D.W.1
Wettenhall, R.E.2
Kudlicki, W.3
Kramer, G.4
Hardesty, B.5
-
255
-
-
0034615701
-
Disruption of hsp90 function results in degradation of the death domain kinase, receptorinteracting protein (RIP), and blockage of tumor necrosis factorinduced nuclear factor-kappaB activation
-
Lewis, J., Devin, A., Miller, A., Lin, Y., Rodriguez, Y., Neckers, L., and Liu, Z. G. (2000) Disruption of hsp90 function results in degradation of the death domain kinase, receptorinteracting protein (RIP), and blockage of tumor necrosis factorinduced nuclear factor-kappaB activation. J. Biol. Chem.,275, 10519-10526.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10519-10526
-
-
Lewis, J.1
Devin, A.2
Miller, A.3
Lin, Y.4
Rodriguez, Y.5
Neckers, L.6
Liu, Z.G.7
-
256
-
-
0031577477
-
Functional importance of heat shock protein 90 associated with insulin receptor on insulin-stimulated mitogenesis
-
Takata, Y., Imamura, T., Iwata, M., Usui, I., Haruta, T., Nandachi, N., Ishiki, M., Sasaoka, T., and Kobayashi, M. (1997) Functional importance of heat shock protein 90 associated with insulin receptor on insulin-stimulated mitogenesis. Biochem. Biophys. Res. Commun.,237, 345-347.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.237
, pp. 345-347
-
-
Takata, Y.1
Imamura, T.2
Iwata, M.3
Usui, I.4
Haruta, T.5
Nandachi, N.6
Ishiki, M.7
Sasaoka, T.8
Kobayashi, M.9
-
257
-
-
0025895949
-
Growth factors acting via tyrosine kinase receptors induce HSP90 alpha gene expression
-
Jerome, V., Leger, J., Devin, J., Baulieu, E. E., and Catelli, M. G. (1991) Growth factors acting via tyrosine kinase receptors induce HSP90 alpha gene expression. Growth Factors,4, 317-327.
-
(1991)
Growth Factors
, vol.4
, pp. 317-327
-
-
Jerome, V.1
Leger, J.2
Devin, J.3
Baulieu, E.E.4
Catelli, M.G.5
-
258
-
-
18744382408
-
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha
-
Marcu, M. G., Doyle, M., Bertolotti, A., Ron, D., Hendershot, L., and Neckers, L. (2002) Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha. Mol. Cell Biol.,22, 8506-8513.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 8506-8513
-
-
Marcu, M.G.1
Doyle, M.2
Bertolotti, A.3
Ron, D.4
Hendershot, L.5
Neckers, L.6
-
259
-
-
0037444766
-
Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability
-
Boudeau, J., Deak, M., Lawlor, M. A., Morrice, N. A., and Alessi, D. R. (2003) Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability. Biochem. J.,370, 849-857.
-
(2003)
Biochem. J.
, vol.370
, pp. 849-857
-
-
Boudeau, J.1
Deak, M.2
Lawlor, M.A.3
Morrice, N.A.4
Alessi, D.R.5
-
260
-
-
0346057795
-
Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37
-
Nony, P., Gaude, H., Rossel, M., Fournier, L., Rouault, J. P., and Billaud, M. (2003) Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37. Oncogene,22, 9165-9175.
-
(2003)
Oncogene
, vol.22
, pp. 9165-9175
-
-
Nony, P.1
Gaude, H.2
Rossel, M.3
Fournier, L.4
Rouault, J.P.5
Billaud, M.6
-
261
-
-
0028023828
-
Association of Hsp90 with cellular Src-family kinases in a cellfree system correlates with altered kinase structure and function
-
Hartson, S. D. and Matts, R. L. (1994) Association of Hsp90 with cellular Src-family kinases in a cellfree system correlates with altered kinase structure and function. Biochemistry,33, 8912-8920.
-
(1994)
Biochemistry
, vol.33
, pp. 8912-8920
-
-
Hartson, S.D.1
Matts, R.L.2
-
262
-
-
0035877701
-
Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily
-
Miyata, Y., Ikawa, Y., Shibuya, M., and Nishida, E. (2001) Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily. J. Biol. Chem.,276, 21841-21848.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21841-21848
-
-
Miyata, Y.1
Ikawa, Y.2
Shibuya, M.3
Nishida, E.4
-
263
-
-
0034629290
-
Disruption of Raf-1/heat shock protein 90 complex and Raf signaling by dexamethasone in mast cells
-
Cissel, D. S. and Beaven, M. A. (2000) Disruption of Raf-1/heat shock protein 90 complex and Raf signaling by dexamethasone in mast cells. J. Biol. Chem.,275, 7066-7070.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7066-7070
-
-
Cissel, D.S.1
Beaven, M.A.2
-
264
-
-
0035003608
-
Hsp90 chaperone complexes are required for the activity and stability of yeast protein kinases Mik1, Wee1 and Swe1
-
Goes, F. S. and Martin, J. (2001) Hsp90 chaperone complexes are required for the activity and stability of yeast protein kinases Mik1, Wee1 and Swe1. Eur. J. Biochem,268, 2281-2289.
-
(2001)
Eur. J. Biochem
, vol.268
, pp. 2281-2289
-
-
Goes, F.S.1
Martin, J.2
-
265
-
-
0036494113
-
Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK({thorn}) CD30({thorn}) lymphoma cells by the Hsp90 antagonist 17-allylamino, 17-demethoxygeldanamycin
-
Bonvini, P., Gastaldi, T., Falini, B., and Rosolen, A. (2002) Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK({thorn}) CD30({thorn}) lymphoma cells by the Hsp90 antagonist 17-allylamino, 17-demethoxygeldanamycin. Cancer Res.,62, 1559-1566.
-
(2002)
Cancer Res.
, vol.62
, pp. 1559-1566
-
-
Bonvini, P.1
Gastaldi, T.2
Falini, B.3
Rosolen, A.4
-
266
-
-
0027095980
-
Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae
-
Flanagan, C. A. and Thorner, J. (1992) Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae. J. Biol. Chem.,267, 24117-24125.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24117-24125
-
-
Flanagan, C.A.1
Thorner, J.2
-
267
-
-
0034805705
-
Regulation of Pim-1 by Hsp90
-
Mizuno, K., Shirogane, T., Shinohara, A., Iwamatsu, A., Hibi, M., and Hirano, T. (2001) Regulation of Pim-1 by Hsp90. Biochem. Biophys. Res. Commun.,281, 663-669.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.281
, pp. 663-669
-
-
Mizuno, K.1
Shirogane, T.2
Shinohara, A.3
Iwamatsu, A.4
Hibi, M.5
Hirano, T.6
-
268
-
-
0032897474
-
Benzoquinoid ansamycins (herbimycin A and geldanamycin) interfere with the maturation of growth factor receptor tyrosine kinases
-
Sakagami, M., Morrison, P., and Welch, W. J. (1999). Benzoquinoid ansamycins (herbimycin A and geldanamycin) interfere with the maturation of growth factor receptor tyrosine kinases. Cell Stress. Chaperones., 4, 19-28
-
(1999)
Cell Stress. Chaperones.
, vol.4
, pp. 19-28
-
-
Sakagami, M.1
Morrison, P.2
Welch, W.J.3
-
269
-
-
0035355510
-
Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability
-
de Carcer, G., do Carmo, A. M., Lallena, M. J., Glover, D. M., and Gonzalez, C. (2001) Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability. EMBO J.,20, 2878-2884.
-
(2001)
EMBO J.
, vol.20
, pp. 2878-2884
-
-
De Carcer, G.1
Do Carmo, A.M.2
Lallena, M.J.3
Glover, D.M.4
Gonzalez, C.5
-
270
-
-
0029824710
-
Nerve growth factor-mediated activation of the mitogen-activated protein (MAP) kinase cascade involves a signaling complex containing B-Raf and HSP90
-
Jaiswal, R. K., Weissinger, E., Kolch, W., and Landreth, G. E. (1996) Nerve growth factor-mediated activation of the mitogen-activated protein (MAP) kinase cascade involves a signaling complex containing B-Raf and HSP90. J. Biol. Chem.,271, 23626-23629.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23626-23629
-
-
Jaiswal, R.K.1
Weissinger, E.2
Kolch, W.3
Landreth, G.E.4
-
271
-
-
0028295650
-
Cell cycle-dependent association of Gag-Mil and hsp90
-
Lovric, J., Bischof, O., and Moelling, K. (1994) Cell cycle-dependent association of Gag-Mil and hsp90. FEBS Lett.,343, 15-21.
-
(1994)
FEBS Lett.
, vol.343
, pp. 15-21
-
-
Lovric, J.1
Bischof, O.2
Moelling, K.3
-
272
-
-
0027433644
-
Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system
-
Stancato, L. F., Chow, Y. H., Hutchison, K. A., Perdew, G. H., Jove, R., and Pratt, W. B. (1993) Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system. J. Biol. Chem.,268, 21711-21716.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21711-21716
-
-
Stancato, L.F.1
Chow, Y.H.2
Hutchison, K.A.3
Perdew, G.H.4
Jove, R.5
Pratt, W.B.6
-
273
-
-
0028227245
-
The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex
-
Wartmann, M. and Davis, R. J. (1994) The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex. J. Biol. Chem.,269, 6695-6701.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6695-6701
-
-
Wartmann, M.1
Davis, R.J.2
-
274
-
-
0028363670
-
Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila
-
Cutforth, T. and Rubin, G. M. (1994) Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila. Cell,77, 1027-1036.
-
(1994)
Cell
, vol.77
, pp. 1027-1036
-
-
Cutforth, T.1
Rubin, G.M.2
-
275
-
-
0033512306
-
Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected]
-
Donze, O. and Picard, D. (1999) Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected]. Mol. Cell Biol.,19, 8422-8432.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 8422-8432
-
-
Donze, O.1
Picard, D.2
-
276
-
-
0034903516
-
Heat shock protein 90 in retinal ganglion cells: association with axonally transported proteins
-
Bernstein, S. L., Russell, P., Wong, P., Fishelevich, R., and Smith, L. E. (2001) Heat shock protein 90 in retinal ganglion cells: association with axonally transported proteins. Vis. Neurosci.,18, 429-436.
-
(2001)
Vis. Neurosci.
, vol.18
, pp. 429-436
-
-
Bernstein, S.L.1
Russell, P.2
Wong, P.3
Fishelevich, R.4
Smith, L.E.5
-
277
-
-
0020321969
-
Association of the transforming proteins of Rous, Fujinami, and Y73 avian sarcoma viruses with the same two cellular proteins
-
Lipsich, L. A., Cutt, J. R., and Brugge, J. S. (1982) Association of the transforming proteins of Rous, Fujinami, and Y73 avian sarcoma viruses with the same two cellular proteins. Mol. Cell Biol.,2, 875-880.
-
(1982)
Mol. Cell Biol.
, vol.2
, pp. 875-880
-
-
Lipsich, L.A.1
Cutt, J.R.2
Brugge, J.S.3
-
278
-
-
0022537770
-
Association of the heat shock protein hsp90 with steroid hormone receptors and tyrosine kinase oncogene products
-
Ziemiecki, A., Catelli, M. G., Joab, I., and Moncharmont, B. (1986) Association of the heat shock protein hsp90 with steroid hormone receptors and tyrosine kinase oncogene products. Biochem. Biophys. Res. Commun.,138, 1298-1307.
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.138
, pp. 1298-1307
-
-
Ziemiecki, A.1
Catelli, M.G.2
Joab, I.3
Moncharmont, B.4
-
279
-
-
0026739438
-
Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system
-
Hutchison, K. A., Brott, B. K., De Leon, J. H., Perdew, G. H., Jove, R., and Pratt, W. B. (1992) Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system. J. Biol. Chem.,267, 2902-2908.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 2902-2908
-
-
Hutchison, K.A.1
Brott, B.K.2
De Leon, J.H.3
Perdew, G.H.4
Jove, R.5
Pratt, W.B.6
-
280
-
-
0019485241
-
A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein
-
Oppermann, H., Levinson, W., and Bishop, J. M. (1981) A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein. Proc. Natl. Acad. Sci. U.S.A,78, 1067-1071.
-
(1981)
Proc. Natl. Acad. Sci. U.S.A
, vol.78
, pp. 1067-1071
-
-
Oppermann, H.1
Levinson, W.2
Bishop, J.M.3
-
281
-
-
0342651927
-
Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins
-
Koyasu, S., Nishida, E., Kadowaki, T., Matsuzaki, F., Iida, K., Harada, F., Kasuga, M., Sakai, H., and Yahara, I. (1986) Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins. Proc. Natl. Acad. Sci. U.S.A,83, 8054-8058.
-
(1986)
Proc. Natl. Acad. Sci. U.S.A
, vol.83
, pp. 8054-8058
-
-
Koyasu, S.1
Nishida, E.2
Kadowaki, T.3
Matsuzaki, F.4
Iida, K.5
Harada, F.6
Kasuga, M.7
Sakai, H.8
Yahara, I.9
-
282
-
-
0034253474
-
Negative regulation of the Apaf-1 apoptosome by Hsp70
-
Saleh, A., Srinivasula, S. M., Balkir, L., Robbins, P. D., and Alnemri, E. S. (2000) Negative regulation of the Apaf-1 apoptosome by Hsp70. Nat. Cell Biol.,2, 476-483.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 476-483
-
-
Saleh, A.1
Srinivasula, S.M.2
Balkir, L.3
Robbins, P.D.4
Alnemri, E.S.5
-
283
-
-
0035816574
-
Apoprotein B degradation is promoted by the molecular chaperones hsp90 and hsp70
-
Gusarova, V., Caplan, A. J., Brodsky, J. L., and Fisher, E. A. (2001) Apoprotein B degradation is promoted by the molecular chaperones hsp90 and hsp70. J. Biol. Chem.,276, 24891-24900.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24891-24900
-
-
Gusarova, V.1
Caplan, A.J.2
Brodsky, J.L.3
Fisher, E.A.4
-
284
-
-
0035815652
-
Regulation of the atrial natriuretic peptide receptor by heat shock protein 90 complexes
-
Kumar, R., Grammatikakis, N., and Chinkers, M. (2001) Regulation of the atrial natriuretic peptide receptor by heat shock protein 90 complexes. J. Biol. Chem.,276, 11371-11375.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11371-11375
-
-
Kumar, R.1
Grammatikakis, N.2
Chinkers, M.3
-
285
-
-
0346996448
-
Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts
-
Zhao, C. and Wang, E. (2004) Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts. Cell Signal.,16, 313-321.
-
(2004)
Cell Signal.
, vol.16
, pp. 313-321
-
-
Zhao, C.1
Wang, E.2
-
286
-
-
0023024149
-
Calmodulinregulated binding of the 90-kDa heat shock protein to actin filaments
-
Nishida, E., Koyasu, S., Sakai, H., and Yahara, I. (1986) Calmodulinregulated binding of the 90-kDa heat shock protein to actin filaments. J. Biol. Chem.,261, 16033-16036.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 16033-16036
-
-
Nishida, E.1
Koyasu, S.2
Sakai, H.3
Yahara, I.4
-
287
-
-
0032878503
-
Localization of calponin binding sites in the structure of 90 kDa heat shock protein (Hsp90)
-
Bogatcheva, N. V., Ma, Y., Urosev, D., and Gusev, N. B. (1999) Localization of calponin binding sites in the structure of 90 kDa heat shock protein (Hsp90). FEBS Lett.,457, 369-374.
-
(1999)
FEBS Lett.
, vol.457
, pp. 369-374
-
-
Bogatcheva, N.V.1
Ma, Y.2
Urosev, D.3
Gusev, N.B.4
-
288
-
-
0028841776
-
Identification of a complex between centrin and heat shock proteins in CSF-arrested Xenopus oocytes and dissociation of the complex following oocyte activation
-
Uzawa, M., Grams, J., Madden, B., Toft, D., and Salisbury, J. L. (1995) Identification of a complex between centrin and heat shock proteins in CSF-arrested Xenopus oocytes and dissociation of the complex following oocyte activation. Dev. Biol.,171, 51-59.
-
(1995)
Dev. Biol.
, vol.171
, pp. 51-59
-
-
Uzawa, M.1
Grams, J.2
Madden, B.3
Toft, D.4
Salisbury, J.L.5
-
289
-
-
0034458959
-
Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin
-
Imai, J. and Yahara, I. (2000) Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin. Mol. Cell Biol.,20, 9262-9270.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 9262-9270
-
-
Imai, J.1
Yahara, I.2
-
290
-
-
0032401771
-
Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome
-
Loo, M. A., Jensen, T. J., Cui, L., Hou, Y., Chang, X. B., and Riordan, J. R. (1998) Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome. EMBO J.,17, 6879-6887.
-
(1998)
EMBO J.
, vol.17
, pp. 6879-6887
-
-
Loo, M.A.1
Jensen, T.J.2
Cui, L.3
Hou, Y.4
Chang, X.B.5
Riordan, J.R.6
-
291
-
-
0037173049
-
Hsp90 enables Ctf13p/Skp1p to nucleate the budding yeast kinetochore
-
Stemmann, O., Neidig, A., Kocher, T., Wilm, M., and Lechner, J. (2002) Hsp90 enables Ctf13p/Skp1p to nucleate the budding yeast kinetochore. Proc. Natl. Acad. Sci. U.S.A,99, 8585-8590.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 8585-8590
-
-
Stemmann, O.1
Neidig, A.2
Kocher, T.3
Wilm, M.4
Lechner, J.5
-
292
-
-
0009621605
-
Dynamic activation of endothelial nitric oxide synthase by Hsp90
-
Garcia-Cardena, G., Fan, R., Shah, V., Sorrentino, R., Cirino, G., Papapetropoulos, A., and Sessa, W. C. (1998) Dynamic activation of endothelial nitric oxide synthase by Hsp90. Nature,392, 821-824.
-
(1998)
Nature
, vol.392
, pp. 821-824
-
-
Garcia-Cardena, G.1
Fan, R.2
Shah, V.3
Sorrentino, R.4
Cirino, G.5
Papapetropoulos, A.6
Sessa, W.C.7
-
293
-
-
2442464375
-
Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG
-
Ficker, E., Dennis, A. T., Wang, L., and Brown, A. M. (2003). Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG. Circ. Res., 92, e87-100.
-
(2003)
Circ. Res.
, vol.92
-
-
Ficker, E.1
Dennis, A.T.2
Wang, L.3
Brown, A.M.4
-
294
-
-
0032100480
-
Molecular chaperone GRP94 binds to the Fanconi anemia group C protein and regulates its intracellular expression
-
Hoshino, T., Wang, J., Devetten, M. P., Iwata, N., Kajigaya, S., Wise, R. J., Liu, J. M., and Youssoufian, H. (1998) Molecular chaperone GRP94 binds to the Fanconi anemia group C protein and regulates its intracellular expression. Blood,91, 4379-4386.
-
(1998)
Blood
, vol.91
, pp. 4379-4386
-
-
Hoshino, T.1
Wang, J.2
Devetten, M.P.3
Iwata, N.4
Kajigaya, S.5
Wise, R.J.6
Liu, J.M.7
Youssoufian, H.8
-
295
-
-
0028181755
-
Association of the beta gamma subunits of trimeric GTP-binding proteins with 90-kDa heat shock protein, hsp90
-
Inanobe, A., Takahashi, K., and Katada, T. (1994) Association of the beta gamma subunits of trimeric GTP-binding proteins with 90-kDa heat shock protein, hsp90. J. Biochem. (Tokyo),115, 486-492.
-
(1994)
J. Biochem. (Tokyo)
, vol.115
, pp. 486-492
-
-
Inanobe, A.1
Takahashi, K.2
Katada, T.3
-
296
-
-
0034695257
-
Degradation of heterotrimeric Galpha(o) subunits via the proteosome pathway is induced by the hsp90-specific compound geldanamycin
-
Busconi, L., Guan, J., and Denker, B. M. (2000) Degradation of heterotrimeric Galpha(o) subunits via the proteosome pathway is induced by the hsp90-specific compound geldanamycin. J. Biol. Chem.,275, 1565-1569.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1565-1569
-
-
Busconi, L.1
Guan, J.2
Denker, B.M.3
-
297
-
-
0035824512
-
Interaction between the G alpha subunit of heterotrimeric G(12) protein and Hsp90 is required for G alpha(12) signaling
-
Vaiskunaite, R., Kozasa, T., and Voyno-Yasenetskaya, T. A. (2001) Interaction between the G alpha subunit of heterotrimeric G(12) protein and Hsp90 is required for G alpha(12) signaling. J. Biol. Chem.,276, 46088-46093.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46088-46093
-
-
Vaiskunaite, R.1
Kozasa, T.2
Voyno-Yasenetskaya, T.A.3
-
298
-
-
0035900746
-
GERp95 belongs to a family of signaltransducing proteins and requires Hsp90 activity for stability and Golgi localization
-
Tahbaz, N., Carmichael, J. B., and Hobman, T. C. (2001) GERp95 belongs to a family of signaltransducing proteins and requires Hsp90 activity for stability and Golgi localization. J. Biol. Chem.,276, 43294-43299.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43294-43299
-
-
Tahbaz, N.1
Carmichael, J.B.2
Hobman, T.C.3
-
299
-
-
0038338320
-
Polymorphic glutathione S-transferase subunit 3 of rat liver exhibits different susceptibilities to carbon tetrachloride: differences in their interactions with heat-shock protein 90
-
Mayama, J., Kumano, T., Hayakari, M., Yamazaki, T., Aizawa, S., Kudo, T., and Tsuchida, S. (2003) Polymorphic glutathione S-transferase subunit 3 of rat liver exhibits different susceptibilities to carbon tetrachloride: differences in their interactions with heat-shock protein 90. Biochem. J.,372, 611-616.
-
(2003)
Biochem. J.
, vol.372
, pp. 611-616
-
-
Mayama, J.1
Kumano, T.2
Hayakari, M.3
Yamazaki, T.4
Aizawa, S.5
Kudo, T.6
Tsuchida, S.7
-
300
-
-
0037962212
-
Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase
-
Venema, R. C., Venema, V. J., Ju, H., Harris, M. B., Snead, C., Jilling, T., Dimitropoulou, C., Maragoudakis, M. E., and Catravas, J. D. (2003). Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase. Am. J. Physiol Heart Circ. Physiol, 285, H669-H678.
-
(2003)
Am. J. Physiol Heart Circ. Physiol
, vol.285
-
-
Venema, R.C.1
Venema, V.J.2
Ju, H.3
Harris, M.B.4
Snead, C.5
Jilling, T.6
Dimitropoulou, C.7
Maragoudakis, M.E.8
Catravas, J.D.9
-
301
-
-
0344631619
-
The 650-kDa 12(S)-hydroxyeicosatetraenoic acid binding complex: occurrence in human platelets, identification of hsp90 as a constituent, and binding properties of its 50-kDa subunit
-
Herbertsson, H., Kuhme, T., and Hammarstrom, S. (1999) The 650-kDa 12(S)-hydroxyeicosatetraenoic acid binding complex: occurrence in human platelets, identification of hsp90 as a constituent, and binding properties of its 50-kDa subunit. Arch. Biochem. Biophys.,367, 33-38.
-
(1999)
Arch. Biochem. Biophys.
, vol.367
, pp. 33-38
-
-
Herbertsson, H.1
Kuhme, T.2
Hammarstrom, S.3
-
302
-
-
0033595753
-
Interactions of Hsp90 with histones and related peptides
-
Schnaider, T., Oikarinen, J., Ishiwatari-Hayasaka, H., Yahara, I., and Csermely, P. (1999) Interactions of Hsp90 with histones and related peptides. Life Sci.,65, 2417-2426.
-
(1999)
Life Sci.
, vol.65
, pp. 2417-2426
-
-
Schnaider, T.1
Oikarinen, J.2
Ishiwatari-Hayasaka, H.3
Yahara, I.4
Csermely, P.5
-
303
-
-
0031042390
-
Potent inhibition of inducible nitric oxide synthase by geldanamycin, a tyrosine kinase inhibitor, in endothelial, smooth muscle cells, and in rat aorta
-
Joly, G. A., Ayres, M., and Kilbourn, R. G. (1997) Potent inhibition of inducible nitric oxide synthase by geldanamycin, a tyrosine kinase inhibitor, in endothelial, smooth muscle cells, and in rat aorta. FEBS Lett.,403, 40-44.
-
(1997)
FEBS Lett.
, vol.403
, pp. 40-44
-
-
Joly, G.A.1
Ayres, M.2
Kilbourn, R.G.3
-
304
-
-
0034914206
-
A molecular chaperone complex at the lysosomal membrane is required for protein translocation
-
Agarraberes, F. A. and Dice, J. F. (2001) A molecular chaperone complex at the lysosomal membrane is required for protein translocation. J. Cell Sci.,114, 2491-2499.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2491-2499
-
-
Agarraberes, F.A.1
Dice, J.F.2
-
305
-
-
0036299036
-
HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors
-
Nakamura, T., Hinagata, J., Tanaka, T., Imanishi, T., Wada, Y., Kodama, T., and Doi, T. (2002) HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors. Biochem. Biophys. Res. Commun.,290, 858-864.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 858-864
-
-
Nakamura, T.1
Hinagata, J.2
Tanaka, T.3
Imanishi, T.4
Wada, Y.5
Kodama, T.6
Doi, T.7
-
306
-
-
0034644778
-
Heat shock protein 90 mediates protein-protein interactions between human aminoacyl-tRNA synthetases
-
Kang, J., Kim, T., Ko, Y. G., Rho, S. B., Park, S. G., Kim, M. J., Kwon, H. J., and Kim, S. (2000) Heat shock protein 90 mediates protein-protein interactions between human aminoacyl-tRNA synthetases. J. Biol. Chem.,275, 31682-31688.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31682-31688
-
-
Kang, J.1
Kim, T.2
Ko, Y.G.3
Rho, S.B.4
Park, S.G.5
Kim, M.J.6
Kwon, H.J.7
Kim, S.8
-
307
-
-
0035798547
-
Inhibition of MDM2 by hsp90 contributes to mutant p53 stabilization
-
Peng, Y., Chen, L., Li, C., Lu, W., and Chen, J. (2001) Inhibition of MDM2 by hsp90 contributes to mutant p53 stabilization. J. Biol. Chem.,276, 40583-40590.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40583-40590
-
-
Peng, Y.1
Chen, L.2
Li, C.3
Lu, W.4
Chen, J.5
-
308
-
-
0029015872
-
ATP induces dissociation of the 90 kDa heat shock protein (hsp90) from F-actin: interference with the binding of heavy meromyosin
-
Kellermayer, M. S. and Csermely, P. (1995) ATP induces dissociation of the 90 kDa heat shock protein (hsp90) from F-actin: interference with the binding of heavy meromyosin. Biochem. Biophys. Res. Commun.,211, 166-174.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.211
, pp. 166-174
-
-
Kellermayer, M.S.1
Csermely, P.2
-
309
-
-
0242556837
-
Cytosolic HSP90 associates with and modulates the Arabidopsis RPM1 disease resistance protein
-
Hubert, D. A., Tornero, P., Belkhadir, Y., Krishna, P., Takahashi, A., Shirasu, K., and Dangl, J. L. (2003) Cytosolic HSP90 associates with and modulates the Arabidopsis RPM1 disease resistance protein. EMBO J.,22, 5679-5689.
-
(2003)
EMBO J.
, vol.22
, pp. 5679-5689
-
-
Hubert, D.A.1
Tornero, P.2
Belkhadir, Y.3
Krishna, P.4
Takahashi, A.5
Shirasu, K.6
Dangl, J.L.7
-
310
-
-
0033556314
-
Neuronal nitricoxide synthase is regulated by the Hsp90-based chaperone system in vivo
-
Bender, A. T., Silverstein, A. M., Demady, D. R., Kanelakis, K. C., Noguchi, S., Pratt, W. B., and Osawa, Y. (1999) Neuronal nitricoxide synthase is regulated by the Hsp90-based chaperone system in vivo. J. Biol. Chem.,274, 1472-1478.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1472-1478
-
-
Bender, A.T.1
Silverstein, A.M.2
Demady, D.R.3
Kanelakis, K.C.4
Noguchi, S.5
Pratt, W.B.6
Osawa, Y.7
-
311
-
-
0242424108
-
Interaction of neuropeptide Y and Hsp90 through a novel peptide binding region
-
Ishiwatari-Hayasaka, H., Maruya, M., Sreedhar, A. S., Nemoto, T. K., Csermely, P., and Yahara, I. (2003) Interaction of neuropeptide Y and Hsp90 through a novel peptide binding region. Biochemistry,42, 12972-12980.
-
(2003)
Biochemistry
, vol.42
, pp. 12972-12980
-
-
Ishiwatari-Hayasaka, H.1
Maruya, M.2
Sreedhar, A.S.3
Nemoto, T.K.4
Csermely, P.5
Yahara, I.6
-
312
-
-
0141621228
-
Tyrosine phosphorylation of HSP90 within the P2X7 receptor complex negatively regulates P2X7 receptors
-
Adinolfi, E., Kim, M., Young, M. T., Di Virgilio, F., and Surprenant, A. (2003) Tyrosine phosphorylation of HSP90 within the P2X7 receptor complex negatively regulates P2X7 receptors. J. Biol. Chem.,278, 37344-37351.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37344-37351
-
-
Adinolfi, E.1
Kim, M.2
Young, M.T.3
Di Virgilio, F.4
Surprenant, A.5
-
313
-
-
0346003805
-
Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis
-
Momose, F., Naito, T., Yano, K., Sugimoto, S., Morikawa, Y., and Nagata, K. (2002) Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis. J. Biol. Chem.,277, 45306-45314.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45306-45314
-
-
Momose, F.1
Naito, T.2
Yano, K.3
Sugimoto, S.4
Morikawa, Y.5
Nagata, K.6
-
314
-
-
0031696368
-
Participation of GRP94-related protein in secretion of pancreatic bile salt-dependent lipase and in its internalization by the intestinal epithelium
-
Bruneau, N., Lombardo, D., and Bendayan, M. (1998). Participation of GRP94-related protein in secretion of pancreatic bile salt-dependent lipase and in its internalization by the intestinal epithelium. J. Cell Sci., 111 (PT 17), 2665-2679.
-
(1998)
J. Cell Sci.
, vol.111
, Issue.17 PT
, pp. 2665-2679
-
-
Bruneau, N.1
Lombardo, D.2
Bendayan, M.3
-
315
-
-
0037040201
-
Host chaperones are recruited in membrane-bound complexes by Plasmodium falciparum
-
Banumathy, G., Singh, V., and Tatu, U. (2002) Host chaperones are recruited in membrane-bound complexes by Plasmodium falciparum. J. Biol. Chem.,277, 3902-3912.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3902-3912
-
-
Banumathy, G.1
Singh, V.2
Tatu, U.3
-
316
-
-
0035980107
-
Thrombin receptor signaling to cytoskeleton requires Hsp90
-
Pai, K. S., Mahajan, V. B., Lau, A., and Cunningham, D. D. (2001) Thrombin receptor signaling to cytoskeleton requires Hsp90. J. Biol. Chem.,276, 32642-32647.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32642-32647
-
-
Pai, K.S.1
Mahajan, V.B.2
Lau, A.3
Cunningham, D.D.4
-
317
-
-
0028352980
-
Purification and characterization of an endogenous inhibitor specific to the Z-Leu-Leu-Leu-MCA degrading activity in proteasome and its identification as heat-shock protein 90
-
Tsubuki, S., Saito, Y., and Kawashima, S. (1994) Purification and characterization of an endogenous inhibitor specific to the Z-Leu-Leu-Leu-MCA degrading activity in proteasome and its identification as heat-shock protein 90. FEBS Lett.,344, 229-233.
-
(1994)
FEBS Lett.
, vol.344
, pp. 229-233
-
-
Tsubuki, S.1
Saito, Y.2
Kawashima, S.3
-
318
-
-
0037110754
-
Rab-alphaGDI activity is regulated by a Hsp90 chaperone complex
-
Sakisaka, T., Meerlo, T., Matteson, J., Plutner, H., and Balch, W. E. (2002) Rab-alphaGDI activity is regulated by a Hsp90 chaperone complex. EMBO J.,21, 6125-6135.
-
(2002)
EMBO J.
, vol.21
, pp. 6125-6135
-
-
Sakisaka, T.1
Meerlo, T.2
Matteson, J.3
Plutner, H.4
Balch, W.E.5
-
319
-
-
0038268180
-
HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo
-
Hu, Y. and Mivechi, N. F. (2003) HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo. J. Biol. Chem.,278, 17299-17306.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17299-17306
-
-
Hu, Y.1
Mivechi, N.F.2
-
320
-
-
0032510950
-
Active participation of Hsp90 in the biogenesis of the trimeric reovirus cell attachment protein sigma1
-
Gilmore, R., Coffey, M. C., and Lee, P. W. (1998) Active participation of Hsp90 in the biogenesis of the trimeric reovirus cell attachment protein sigma1. J. Biol. Chem.,273, 15227-15233.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15227-15233
-
-
Gilmore, R.1
Coffey, M.C.2
Lee, P.W.3
-
321
-
-
0344270928
-
Regulation of survivin function by Hsp90
-
Fortugno, P., Beltrami, E., Plescia, J., Fontana, J., Pradhan, D., Marchisio, P. C., Sessa, W. C., and Altieri, D. C. (2003) Regulation of survivin function by Hsp90. Proc. Natl. Acad. Sci. U.S.A,100, 13791-13796.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 13791-13796
-
-
Fortugno, P.1
Beltrami, E.2
Plescia, J.3
Fontana, J.4
Pradhan, D.5
Marchisio, P.C.6
Sessa, W.C.7
Altieri, D.C.8
-
322
-
-
0033485717
-
Alpha-complemented betagalactosidase.An in vivo model substrate for the molecular chaperone heat-shock protein 90 in yeast
-
Abbas-Terki, T. and Picard, D. (1999) Alpha-complemented betagalactosidase. An in vivo model substrate for the molecular chaperone heat-shock protein 90 in yeast. Eur. J. Biochem.,266, 517-523.
-
(1999)
Eur. J. Biochem.
, vol.266
, pp. 517-523
-
-
Abbas-Terki, T.1
Picard, D.2
-
323
-
-
0030666195
-
Thyroglobulin transport along the secretory pathway.Investigation of the role of molecular chaperone, GRP94, in protein export from the endoplasmic reticulum
-
Muresan, Z. and Arvan, P. (1997) Thyroglobulin transport along the secretory pathway. Investigation of the role of molecular chaperone, GRP94, in protein export from the endoplasmic reticulum. J. Biol. Chem.,272, 26095-26102.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26095-26102
-
-
Muresan, Z.1
Arvan, P.2
-
324
-
-
0023766565
-
Evidence that the 90-kilodalton heat shock protein is associated with tubulin-containing complexes in L cell cytosol and in intact PtK cells
-
Sanchez, E. R., Redmond, T., Scherrer, L. C., Bresnick, E. H., Welsh, M. J., and Pratt, W. B. (1988) Evidence that the 90-kilodalton heat shock protein is associated with tubulin-containing complexes in L cell cytosol and in intact PtK cells. Mol. Endocrinol.,2, 756-760.
-
(1988)
Mol. Endocrinol.
, vol.2
, pp. 756-760
-
-
Sanchez, E.R.1
Redmond, T.2
Scherrer, L.C.3
Bresnick, E.H.4
Welsh, M.J.5
Pratt, W.B.6
-
325
-
-
0026808864
-
The endoplasmic reticulum stress protein GRP94, in addition to BiP, associates with unassembled immunoglobulin chains
-
Melnick, J., Aviel, S., and Argon, Y. (1992) The endoplasmic reticulum stress protein GRP94, in addition to BiP, associates with unassembled immunoglobulin chains. J. Biol. Chem.,267, 21303-21306.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 21303-21306
-
-
Melnick, J.1
Aviel, S.2
Argon, Y.3
-
326
-
-
0036149214
-
Molecular chaperone Hsp90 is important for vaccinia virus growth in cells
-
Hung, J. J., Chung, C. S., and Chang, W. (2002) Molecular chaperone Hsp90 is important for vaccinia virus growth in cells. J. Virol.,76, 1379-1390.
-
(2002)
J. Virol.
, vol.76
, pp. 1379-1390
-
-
Hung, J.J.1
Chung, C.S.2
Chang, W.3
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