Potent inhibition of inducible nitric oxide synthase by geldanamycin, a tyrosine kinase inhibitor, in endothelial, smooth muscle cells, and in rat aorta

FEBS Letters

Volumn 403, Issue 1, 1997, Pages 40-44

  Joly, Ghislaine A ^a   Ayres, Mary ^a   Kilbourn, Robert G ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Artery; Endothelial and smooth muscle cell; Inducible nitric oxide synthase; Tyrosine kinase inhibitor

Indexed keywords

CYTOKINE; ENDOTOXIN; GELDANAMYCIN; GENISTEIN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; PROTEIN TYROSINE KINASE INHIBITOR; TYRPHOSTIN;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; BRAIN; CONTROLLED STUDY; ENDOTHELIUM CELL; IMMUNOSTIMULATION; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANIMALS; AORTA; BENZOQUINONES; BRAIN; CELLS, CULTURED; CYTOKINES; ENDOTHELIUM; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENISTEIN; INTERLEUKIN-1; ISOFLAVONES; LACTAMS, MACROCYCLIC; LIPOPOLYSACCHARIDES; MALE; MICE; MUSCLE, SMOOTH; NITRIC OXIDE SYNTHASE; NITRITES; PROTEIN-TYROSINE KINASES; QUINONES; RATS; RATS, WISTAR; VASCULAR RESISTANCE;

EID: 0031042390     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00004-5     Document Type: Article

References (26)

1. Lowenstein, C.J. and Snyder, S.H. (1992) Cell 70, 705-707.
2. Kilbourn, R.G., Jubran, A. and Gross, S.S. (1990) Biochem. Biophys. Res. Commun. 172, 1132-1138.
3. Julou-Schaeffer, G., Gray, G., Fleming, I., Schott, C., Parrat, J.R. and Stoclet, J.C. (1990) Am. J. Physiol. 259, H1038-H1043.
4. Koide, M., Kawahara, Y., Nakayama, I., Tsuda, T. and Yokoyama, M. (1993) J. Biol. Chem. 268, 24959-24966.
5. Bulut, T., Servern, A. and Liew, F.Y. (1993) Biochem. Biophys. Res. Commun. 195, 1134-1138.
6. Servern, A., Wakelam, M.J. and Liew, F.Y. (1992) Biochem. Biophys. Res. Commun. 188, 997-1002.
7. Hortelano, S., Genaro, A.M. and Bosca, L. (1993) FEBS Lett. 320, 135-139.
8. Geng, Y., Maier, R. and Lotz, M. (1995) J. Cell. Physiol. 163, 545-554.
9. White, J.R. and Lee, J. (1993) Agents Actions 39, C73-C76.
10. Dong, Z., Qi, X., Xie, K. and Fidler, I.J. (1993) J. Immunol. 151, 2717-2724.
11. Marczin, N., Papapetropoulos, A. and Catravas, J.D. (1993) Am. J. Physiol. 265, H1014-H1018.
12. Novogrodsky, A., Vanichkin, A., Patya, M., Gazit, A., Osherov, N. and Levitzki, A. (1994) Science 264, 1319-1321.
13. Goss, S.S. and Levi, R. (1992) J. Biol. Chem. 267, 25722-25729.
14. Joly, G.A., Ayres, M., Chelly, F. and Kilbourn, R.G. (1994) 199, 147-154.
15. Nathan, C. (1992) FASEB J. 6, 3051-3064.
16. Gross, S.S., Jaffe, E.A., Levi, R. and Kilbourn, R.G. (1990) Biochem. Biophys. Res. Commun. 178, 823-829.
17. Reifel, A.E., Calnek, D.S. and Grinnell, B.W. (1994) J. Biol. Chem. 269, 23861-23864.
18. Levitzki, A. and Gazit, A. (1995) Science 267, 1782-1788.
19. Smirnov, S.V. and Aronson, P.I. (1995) Circ. Res. 76, 310-316.
20. Gould, E.M., Rembold, C.M. and Murphy, R.A. (1995) Am. J. Physiol. 268, C1425-C1429.
21. Iwasaki, T., Uehara, Y., Graves, L., Rachie, N. and Bomsztyk, K. (1992) FEBS Lett. 298, 240-244.
22. Joshi-Barve, S.S., Rangnekar, V.V., Sell, S.F. and Rangnekar, V.M. (1993) J. Biol. Chem. 268, 18018-18029.
23. Baeuerle, P.A. and Henkel, T. (1994) Annu. Rev. Immunol. 12, 141-179.
24. Miyamoto, S. and Verma, I.M. (1995) Adv. Cancer Res. 66, 255-292.
25. Xie, Q.W., Kashiwabara, Y. and Nathan, C. (1994) J. Biol. Chem. 269, 4705-4708.
26. Rzymkiewicz, D.M., DuMaine, J. and Morrison, A.R. (1995) Kidney Int. 47, 1354-1363.