High Affinity Binding of Hsp90 Is Triggered by Multiple Discrete Segments of Its Kinase Clients

Biochemistry

Volumn 42, Issue 43, 2003, Pages 12550-12561

  Scroggins, Bradley T ^a   Prince, Thomas ^a   Shao, Jieya ^a   Uma, Sheri ^a   Huang, Wenjun ^a   Guo, Yanwen ^a   Yun, Bo Geon ^a   Hedman, Karla ^a   Matts, Robert L ^a   Hartson, Steven D ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYSIS; CRYSTAL STRUCTURE;

PROTEIN KINASES;

PROTEINS;

CELL CYCLE PROTEIN 37; CHAPERONE; HEAT SHOCK PROTEIN 90; HEME REGULATED EIF2A KINASE; MOLYBDIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN; PROTEIN CYP40; PROTEIN FKBP52; PROTEIN KINASE; PROTEIN KINASE LCK; PROTEIN P23; PROTEIN PHOSPHATASE 5; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION;

CATALYTIC DOMAIN; HSP90 HEAT-SHOCK PROTEINS; MODELS, MOLECULAR; PHOSPHOTRANSFERASES; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 0242318392     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035001t     Document Type: Article

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