-
1
-
-
0026085424
-
Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control
-
Abastado, J. P., P. F. Miller, B. M. Jackson, and A. G. Hinnebusch. 1991. Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control. Mol. Cell. Biol. 11:485-496.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 485-496
-
-
Abastado, J.P.1
Miller, P.F.2
Jackson, B.M.3
Hinnebusch, A.G.4
-
2
-
-
0028589101
-
A role for Hsp90 in cell cycle control: Weel tyrosine kinase activity requires interaction with Hsp90
-
Aligue, R., H. Akhavan-Niak, and P. Russell. 1994. A role for Hsp90 in cell cycle control: Weel tyrosine kinase activity requires interaction with Hsp90. EMBO J. 13:6099-6106.
-
(1994)
EMBO J.
, vol.13
, pp. 6099-6106
-
-
Aligue, R.1
Akhavan-Niak, H.2
Russell, P.3
-
3
-
-
0029737509
-
Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90
-
Blagosklonny, M. V., J. Toretsky, S. Bohen, and L. Neckers. 1996. Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90. Proc. Natl. Acad. Sci. USA 93:8379-8383.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8379-8383
-
-
Blagosklonny, M.V.1
Toretsky, J.2
Bohen, S.3
Neckers, L.4
-
4
-
-
0028858102
-
Hsp90 mutants disrupt glucocorticoid receptor ligand binding and destabilize aporeceptor complexes
-
Bohen, S. P. 1995. Hsp90 mutants disrupt glucocorticoid receptor ligand binding and destabilize aporeceptor complexes. J. Biol. Chem. 270:29433-29438.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29433-29438
-
-
Bohen, S.P.1
-
5
-
-
0031868061
-
Genetic and biochemical analysis of p23 and ansamycin antibiotics in the function of Hsp90-dependent signaling proteins
-
Bohen, S. P. 1998. Genetic and biochemical analysis of p23 and ansamycin antibiotics in the function of Hsp90-dependent signaling proteins. Mol. Cell. Biol. 18:3330-3339.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3330-3339
-
-
Bohen, S.P.1
-
6
-
-
0027359404
-
Isolation of Hsp90 mutants by screening for decreased steroid receptor function
-
Bohen, S. P., and K. R. Yamamoto. 1993. Isolation of Hsp90 mutants by screening for decreased steroid receptor function. Proc. Natl. Acad. Sci. USA 90:11424-11428.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11424-11428
-
-
Bohen, S.P.1
Yamamoto, K.R.2
-
7
-
-
0024421221
-
hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures
-
Borkovich, K. A., F. W. Farrelly, D. B. Finkelstein, J. Taulien, and S. Lindquist. 1989. hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures. Mol. Cell. Biol. 9:3919-3930.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 3919-3930
-
-
Borkovich, K.A.1
Farrelly, F.W.2
Finkelstein, D.B.3
Taulien, J.4
Lindquist, S.5
-
8
-
-
0031013723
-
In vivo analysis of the Hsp90 cochaperone St1 (p60)
-
Chang, H. C., D. F. Nathan, and S. Lindquist. 1997. In vivo analysis of the Hsp90 cochaperone St1 (p60). Mol. Cell. Biol. 17:318-325.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 318-325
-
-
Chang, H.C.1
Nathan, D.F.2
Lindquist, S.3
-
9
-
-
0029760873
-
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock
-
Chen, C. F., Y. Chen, K. Dai, P. L. Chen, D. J. Riley, and W. H. Lee. 1996. A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock. Mol. Cell. Biol. 16:4691-4699.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4691-4699
-
-
Chen, C.F.1
Chen, Y.2
Dai, K.3
Chen, P.L.4
Riley, D.J.5
Lee, W.H.6
-
10
-
-
0028935374
-
Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase
-
Chen, J. J., and I. M. London. 1995. Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase. Trends Biochem. Sci. 20:105-108.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 105-108
-
-
Chen, J.J.1
London, I.M.2
-
11
-
-
0025779365
-
Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: Homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase
-
Chen, J. J., M. S. Throop, L. Gehrke, I. Kuo, J. K. Pal, M. Brodsky, and I. M. London. 1991. Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase. Proc. Natl. Acad. Sci. USA 88:7729-7733.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7729-7733
-
-
Chen, J.J.1
Throop, M.S.2
Gehrke, L.3
Kuo, I.4
Pal, J.K.5
Brodsky, M.6
London, I.M.7
-
12
-
-
0031873752
-
The 90-kDa molecular chaperone family: Structure, function, and clinical applications. A comprehensive review
-
Csermely, P., T. Schnaider, C. Soti, Z. Prohaszka, and G. Nardai. 1998. The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review. Pharmacol. Ther. 79:129-168.
-
(1998)
Pharmacol. Ther.
, vol.79
, pp. 129-168
-
-
Csermely, P.1
Schnaider, T.2
Soti, C.3
Prohaszka, Z.4
Nardai, G.5
-
13
-
-
0028363670
-
Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila
-
Culforth, T., and G. M. Rubin. 1994. Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila. Cell 77: 1027-1036.
-
(1994)
Cell
, vol.77
, pp. 1027-1036
-
-
Culforth, T.1
Rubin, G.M.2
-
14
-
-
0030808079
-
Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus
-
Czar, M. J., M. D. Galigniana, A. M. Silverstein, and W. B. Pratt. 1997. Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus. Biochemistry 36:7776-7785.
-
(1997)
Biochemistry
, vol.36
, pp. 7776-7785
-
-
Czar, M.J.1
Galigniana, M.D.2
Silverstein, A.M.3
Pratt, W.B.4
-
15
-
-
0029838168
-
Physical interaction of mammalian CDC37 with CDK4
-
Dai, K., R. Kobayashi, and D. Beach. 1996. Physical interaction of mammalian CDC37 with CDK4. J. Biol. Chem. 271:22030-22034.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22030-22034
-
-
Dai, K.1
Kobayashi, R.2
Beach, D.3
-
16
-
-
0030267336
-
The eIF-2alpha kinases and the control of protein synthesis
-
de Haro, C., R. Mendez, and J. Santoyo. 1996. The eIF-2alpha kinases and the control of protein synthesis. FASEB J. 10:1378-1387.
-
(1996)
FASEB J.
, vol.10
, pp. 1378-1387
-
-
De Haro, C.1
Mendez, R.2
Santoyo, J.3
-
17
-
-
0030907057
-
Using GCN4 as a reporter of eIF2 alpha phosphorylation and translational regulation in yeast
-
Dever, T. E. 1997. Using GCN4 as a reporter of eIF2 alpha phosphorylation and translational regulation in yeast. Methods 11:403-417.
-
(1997)
Methods
, vol.11
, pp. 403-417
-
-
Dever, T.E.1
-
18
-
-
0026556814
-
Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast
-
Dever, T. E., L. Feng, R. C. Wek, A. M. Cigan, T. F. Donahue, and A. G. Hinnebusch. 1992. Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast. Cell 68:585-596.
-
(1992)
Cell
, vol.68
, pp. 585-596
-
-
Dever, T.E.1
Feng, L.2
Wek, R.C.3
Cigan, A.M.4
Donahue, T.F.5
Hinnebusch, A.G.6
-
19
-
-
0029658298
-
CDC37 is required for p60v-src activity in yeast
-
Dey, B., J. J. Lightbody, and F. Boschelli. 1996. CDC37 is required for p60v-src activity in yeast. Mol. Biol. Cell 7:1405-1417.
-
(1996)
Mol. Biol. Cell
, vol.7
, pp. 1405-1417
-
-
Dey, B.1
Lightbody, J.J.2
Boschelli, F.3
-
20
-
-
0030869037
-
Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70
-
Dittmar, K. D., D. R. Demady, L. F. Stancato, P. Krishna, and W. B. Pratt. 1997. Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70. J. Biol. Chem. 272:21213-21220.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21213-21220
-
-
Dittmar, K.D.1
Demady, D.R.2
Stancato, L.F.3
Krishna, P.4
Pratt, W.B.5
-
21
-
-
17544384391
-
Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate
-
Dittmar, K. D., K. A. Hutchison, J. K. Owens-Grillo, and W. B. Pratt. 1996. Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate. J. Biol. Chem. 271:12833-12839.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12833-12839
-
-
Dittmar, K.D.1
Hutchison, K.A.2
Owens-Grillo, J.K.3
Pratt, W.B.4
-
22
-
-
0030989277
-
Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation
-
Dittmar, K. D., and W. B. Pratt. 1997. Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation. J. Biol. Chem. 272:13047-13054.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13047-13054
-
-
Dittmar, K.D.1
Pratt, W.B.2
-
23
-
-
0032563195
-
Requirement for Hsp90 and a CyP-40-type cyclophilin in negative regulation of the heat shock response
-
Duina, A. A., H. M. Kalton, and R. F. Gaber. 1998. Requirement for Hsp90 and a CyP-40-type cyclophilin in negative regulation of the heat shock response. J. Biol. Chem. 273:18974-18978.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18974-18978
-
-
Duina, A.A.1
Kalton, H.M.2
Gaber, R.F.3
-
24
-
-
0031832233
-
SBA1 encodes a yeast hsp90 cochaperone that is homologous to vertebrate p23 proteins
-
Fang, Y., A. E. Fliss, J. Rao, and A. J. Caplan. 1998. SBA1 encodes a yeast hsp90 cochaperone that is homologous to vertebrate p23 proteins. Mol. Cell. Biol. 18:3727-3734.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3727-3734
-
-
Fang, Y.1
Fliss, A.E.2
Rao, J.3
Caplan, A.J.4
-
25
-
-
0030659844
-
Differential in vivo regulation of steroid hormone receptor activation by Cdc37p
-
Fliss, A. E., Y. Fang, F. Boschelli, and A. J. Caplan. 1997. Differential in vivo regulation of steroid hormone receptor activation by Cdc37p. Mol. Cell. Biol. 8:2501-2509.
-
(1997)
Mol. Cell. Biol.
, vol.8
, pp. 2501-2509
-
-
Fliss, A.E.1
Fang, Y.2
Boschelli, F.3
Caplan, A.J.4
-
26
-
-
0025869164
-
GCD2, a translational repressor of the GCN4 gene, has a general function in the initiation of protein synthesis in Saccharomyces cerevisiae
-
Foiani, M., A. M. Cigan, C. J. Paddon, S. Harashima, and A. G. Hinnebusch. 1991. GCD2, a translational repressor of the GCN4 gene, has a general function in the initiation of protein synthesis in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:3203-3216.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 3203-3216
-
-
Foiani, M.1
Cigan, A.M.2
Paddon, C.J.3
Harashima, S.4
Hinnebusch, A.G.5
-
27
-
-
0029852712
-
Molecular chaperone machines: Chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23
-
Freeman, B. C., D. O. Toft, and R. I. Morimoto. 1996. Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23. Science 274:1718-1720.
-
(1996)
Science
, vol.274
, pp. 1718-1720
-
-
Freeman, B.C.1
Toft, D.O.2
Morimoto, R.I.3
-
28
-
-
0029017132
-
Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins
-
Gerber, M. R., A. Farrell, R. J. Deshaies, I. Herskowitz, and D. O. Morgan. 1995. Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins. Proc. Natl. Acad. Sci. USA 92:4651-4655.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4651-4655
-
-
Gerber, M.R.1
Farrell, A.2
Deshaies, R.J.3
Herskowitz, I.4
Morgan, D.O.5
-
29
-
-
0021846299
-
A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae
-
Hinnebusch, A. G. 1985. A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 5:2349-2360.
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 2349-2360
-
-
Hinnebusch, A.G.1
-
30
-
-
0028695223
-
The eIF-2 alpha kinases: Regulators of protein synthesis in starvation and stress
-
Hinnebusch, A. G. 1994. The eIF-2 alpha kinases: regulators of protein synthesis in starvation and stress. Semin. Cell Biol. 5:417-426.
-
(1994)
Semin. Cell Biol.
, vol.5
, pp. 417-426
-
-
Hinnebusch, A.G.1
-
31
-
-
0030803256
-
Translational regulation of yeast GCN4. A window on factors that control initiator-tRNA binding to the ribosome
-
Hinnebusch, A. G. 1997. Translational regulation of yeast GCN4. A window on factors that control initiator-tRNA binding to the ribosome. J. Biol. Chem. 272:21661-21664.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21661-21664
-
-
Hinnebusch, A.G.1
-
32
-
-
0031018112
-
Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids
-
Hu, J., D. O. Toft, and C. Seeger. 1997. Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids. EMBO J. 16:59-68.
-
(1997)
EMBO J.
, vol.16
, pp. 59-68
-
-
Hu, J.1
Toft, D.O.2
Seeger, C.3
-
33
-
-
0028284571
-
Assisting spontaneity: The role of Hsp90 and small Hsps as molecular chaperones
-
Jakob, U., and J. Buchner. 1994. Assisting spontaneity: the role of Hsp90 and small Hsps as molecular chaperones. Trends Biochem. Sci. 19:205-211.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 205-211
-
-
Jakob, U.1
Buchner, J.2
-
34
-
-
0028940309
-
Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase. Implications for heat shock in vivo
-
Jakob, U., H. Lilie, I. Meyer, and J. Buchner. 1995. Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase. Implications for heat shock in vivo. J. Biol. Chem. 270:7288-7294.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7288-7294
-
-
Jakob, U.1
Lilie, H.2
Meyer, I.3
Buchner, J.4
-
35
-
-
0030745769
-
Cdc37 is a molecular chaperone with specific functions in signal transduction
-
Kimura, Y., S. L. Rutherford, V. Miyata, I. Yahara, B. C. Freeman, L. Yue, R. I. Morimoto, and S. Lindquist. 1997. Cdc37 is a molecular chaperone with specific functions in signal transduction. Genes Dev. 11:1775-1785.
-
(1997)
Genes Dev.
, vol.11
, pp. 1775-1785
-
-
Kimura, Y.1
Rutherford, S.L.2
Miyata, V.3
Yahara, I.4
Freeman, B.C.5
Yue, L.6
Morimoto, R.I.7
Lindquist, S.8
-
36
-
-
0031795189
-
Hsp90 is required for pheromone signaling in yeast
-
Louvion, J. F., T. Abbas-Terki, and D. Picard. 1998. Hsp90 is required for pheromone signaling in yeast. Mol. Cell. Biol. 9:3071-3083.
-
(1998)
Mol. Cell. Biol.
, vol.9
, pp. 3071-3083
-
-
Louvion, J.F.1
Abbas-Terki, T.2
Picard, D.3
-
37
-
-
0026725775
-
Regulation of heme-controlled eukaryotic polypeptide chain initiation factor 2 alpha-subunit kinase of reticulocyte lysates
-
Mendez, R., A. Moreno, and C. de Haro. 1992. Regulation of heme-controlled eukaryotic polypeptide chain initiation factor 2 alpha-subunit kinase of reticulocyte lysates. J. Biol. Chem. 267:11500-11507.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11500-11507
-
-
Mendez, R.1
Moreno, A.2
De Haro, C.3
-
38
-
-
0031833450
-
The nuclear receptor ligand-binding domain: Structure and function
-
Moras, D., and H. Gronemeyer. 1998. The nuclear receptor ligand-binding domain: structure and function. Curr. Opin. Cell Biol. 10:384-391.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 384-391
-
-
Moras, D.1
Gronemeyer, H.2
-
39
-
-
0022512237
-
Multiple upstream AUG codons mediate translational control of GCN4
-
Mueller, P. P., and A. G. Hinnebusch. 1986. Multiple upstream AUG codons mediate translational control of GCN4. Cell 45:201-207.
-
(1986)
Cell
, vol.45
, pp. 201-207
-
-
Mueller, P.P.1
Hinnebusch, A.G.2
-
40
-
-
0030324952
-
A pathway of multi-chaperone interactions common to diverse regulatory proteins: Estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor
-
Nair, S. C., E. J. Toran, R. A. Rimerman, S. Hjermstad, T. E. Smithgall, and D. F. Smith. 1996. A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor. Cell Stress Chaperones 1:237-250.
-
(1996)
Cell Stress Chaperones
, vol.1
, pp. 237-250
-
-
Nair, S.C.1
Toran, E.J.2
Rimerman, R.A.3
Hjermstad, S.4
Smithgall, T.E.5
Smith, D.F.6
-
41
-
-
0029037110
-
Mutational analysis of Hsp90 function: Interactions with a steroid receptor and a protein kinase
-
Nathan, D. F., and S. Lindquist. 1995. Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase. Mol. Cell. Biol. 15:3917-3925.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3917-3925
-
-
Nathan, D.F.1
Lindquist, S.2
-
42
-
-
0030667932
-
In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone
-
Nathan, D. F., M. H. Vos, and S. Lindquist. 1997. In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone. Proc. Natl. Acad. Sci. USA 94:12949-12956.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12949-12956
-
-
Nathan, D.F.1
Vos, M.H.2
Lindquist, S.3
-
43
-
-
0024469206
-
Isolation and characterization of STI1, a stress-inducible gene from Saccharomyces cerevisiae
-
Nicolet, C. M., and E. A. Craig. 1989. Isolation and characterization of STI1, a stress-inducible gene from Saccharomyces cerevisiae. Mol. Cell. Biol. 9:3638-3646.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 3638-3646
-
-
Nicolet, C.M.1
Craig, E.A.2
-
44
-
-
0031853386
-
Isolation of the gene encoding the drosophila melanogaster homolog of the saccharomyces cerevisiae GCN2 eIF-2alpha kinase
-
Olsen, D. S., B. Jordan, D. Chen, R. C. Wek, and D. R. Cavener. 1998. Isolation of the gene encoding the drosophila melanogaster homolog of the saccharomyces cerevisiae GCN2 eIF-2alpha kinase. Genetics 149:1495-1509.
-
(1998)
Genetics
, vol.149
, pp. 1495-1509
-
-
Olsen, D.S.1
Jordan, B.2
Chen, D.3
Wek, R.C.4
Cavener, D.R.5
-
45
-
-
0028964571
-
Trypanosoma cruzi heat-shock protein 90 can functionally complement yeast
-
Palmer, G., J. F. Louvion, R. S. Tibbetts, D. M. Engman, and D. Picard. 1995. Trypanosoma cruzi heat-shock protein 90 can functionally complement yeast. Mol. Biochem. Parasitol. 70:199-202.
-
(1995)
Mol. Biochem. Parasitol.
, vol.70
, pp. 199-202
-
-
Palmer, G.1
Louvion, J.F.2
Tibbetts, R.S.3
Engman, D.M.4
Picard, D.5
-
46
-
-
0030935063
-
A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37
-
Perdew, G. H., H. Wiegand, J. P. Vanden Heuvel, C. Mitchell, and S. S. Singh. 1997. A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37. Biochemistry 36:3600-3607.
-
(1997)
Biochemistry
, vol.36
, pp. 3600-3607
-
-
Perdew, G.H.1
Wiegand, H.2
Vanden Heuvel, J.P.3
Mitchell, C.4
Singh, S.S.5
-
47
-
-
0025175208
-
Reduced levels of hsp90 compromise steroid receptor action in vivo
-
Picard, D., B. Khursheed, M. J. Garabedian, M. G. Fortin, S. Lindquist, and K. R. Yamamoto. 1990. Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature 348:166-168.
-
(1990)
Nature
, vol.348
, pp. 166-168
-
-
Picard, D.1
Khursheed, B.2
Garabedian, M.J.3
Fortin, M.G.4
Lindquist, S.5
Yamamoto, K.R.6
-
48
-
-
0031895351
-
The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors
-
Pratt, W. B. 1998. The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors. Proc. Soc. Exp. Biol. Med. 217:420-434.
-
(1998)
Proc. Soc. Exp. Biol. Med.
, vol.217
, pp. 420-434
-
-
Pratt, W.B.1
-
49
-
-
0030925683
-
Steroid receptor interactions with heat shock protein and immunophilin chaperones
-
Pratt, W. B., and D. O. Toft. 1997. Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocrinol. Rev. 18:306-360.
-
(1997)
Endocrinol. Rev.
, vol.18
, pp. 306-360
-
-
Pratt, W.B.1
Toft, D.O.2
-
50
-
-
0031946361
-
Dimerization by translation initiation factor 2 kinase GCN2 is mediated by interactions in the C-terminal ribosome-binding region and the protein kinase domain
-
Qiu, H., M. T. Garcia-Barrio, and A. G. Hinnebusch. 1998. Dimerization by translation initiation factor 2 kinase GCN2 is mediated by interactions in the C-terminal ribosome-binding region and the protein kinase domain. Mol. Cell. Biol. 18:2697-2711.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2697-2711
-
-
Qiu, H.1
Garcia-Barrio, M.T.2
Hinnebusch, A.G.3
-
51
-
-
0026495211
-
Mutations activating the yeast eIF-2α kinase GCN2: Isolation of alleles altering the domain related to histidyl-tRNA synthetases
-
Ramirez, M., R. C. Wek, C. R. Vazquez de Aldana, B. M. Jackson, B. Freeman, and A. G. Hinnebusch. 1992. Mutations activating the yeast eIF-2α kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases. Mol. Cell. Biol. 12:5801-5815.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5801-5815
-
-
Ramirez, M.1
Wek, R.C.2
Vazquez De Aldana, C.R.3
Jackson, B.M.4
Freeman, B.5
Hinnebusch, A.G.6
-
52
-
-
17544395282
-
The PKR protein kinase - An interferon-inducible regulator of cell growth and differentiation
-
Samuel, C. E., K. L. Kuhen, C. X. George, L. G. Ortega, R. Rende-Fournier, and H. Tanaka. 1997. The PKR protein kinase - an interferon-inducible regulator of cell growth and differentiation. Int. J. Hematol. 65:227-237.
-
(1997)
Int. J. Hematol.
, vol.65
, pp. 227-237
-
-
Samuel, C.E.1
Kuhen, K.L.2
George, C.X.3
Ortega, L.G.4
Rende-Fournier, R.5
Tanaka, H.6
-
53
-
-
0030911360
-
Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2alpha (eIF-2alpha) kinase from Drosophila melanogaster. Homology to yeast GCN2 protein kinase
-
Santoyo, J., J. Alcalde, R. Mendez, D. Pulido, and C. de Haro. 1997. Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2alpha (eIF-2alpha) kinase from Drosophila melanogaster. Homology to yeast GCN2 protein kinase. J. Biol. Chem. 272:12544-12550.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12544-12550
-
-
Santoyo, J.1
Alcalde, J.2
Mendez, R.3
Pulido, D.4
De Haro, C.5
-
54
-
-
0032493732
-
cpc-3, the Neurospora crassa homologue of yeast GCN2, encodes a polypeptide with juxtaposed eIF2alpha kinase and histidyl-tRNA synthetase-related domains required for general amino acid control
-
Sattlegger, E., A. G. Hinnebusch, and I. B. Barthelmess. 1998. cpc-3, the Neurospora crassa homologue of yeast GCN2, encodes a polypeptide with juxtaposed eIF2alpha kinase and histidyl-tRNA synthetase-related domains required for general amino acid control. J. Biol. Chem. 273:20404-20416.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20404-20416
-
-
Sattlegger, E.1
Hinnebusch, A.G.2
Barthelmess, I.B.3
-
55
-
-
0029963674
-
Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90
-
Schneider, C., L. Sepp-Lorenzino, E. Nimmesgern, O. Ouerfelli, S. Danishefsky, N. Rosen, and F. U. Hartl. 1996. Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90. Proc. Natl. Acad. Sci. USA 93:14536-14541.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14536-14541
-
-
Schneider, C.1
Sepp-Lorenzino, L.2
Nimmesgern, E.3
Ouerfelli, O.4
Danishefsky, S.5
Rosen, N.6
Hartl, F.U.7
-
56
-
-
0026020420
-
Vectors for expression of cloned genes in yeast: Regulation, overproduction, and underproduction
-
Schneider, J. C., and L. Guarente. 1991. Vectors for expression of cloned genes in yeast: regulation, overproduction, and underproduction. Methods Enzymol. 194:373-388.
-
(1991)
Methods Enzymol.
, vol.194
, pp. 373-388
-
-
Schneider, J.C.1
Guarente, L.2
-
57
-
-
0028786332
-
Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association
-
Schulte, T. W., M. V. Blagosklonny, C. Ingui, and L. Neckers. 1995. Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association. J. Biol. Chem. 270:24585-24588.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24585-24588
-
-
Schulte, T.W.1
Blagosklonny, M.V.2
Ingui, C.3
Neckers, L.4
-
58
-
-
0030810984
-
The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin
-
Segnitz, B., and U. Gehring. 1997. The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin. J. Biol. Chem. 272:18694-18701.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18694-18701
-
-
Segnitz, B.1
Gehring, U.2
-
59
-
-
0024669291
-
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
-
Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
-
(1989)
Genetics
, vol.122
, pp. 19-27
-
-
Sikorski, R.S.1
Hieter, P.2
-
60
-
-
0027484097
-
Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes
-
Smith, D. F. 1993. Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes. Mol. Endocrinol. 7:1418-1429.
-
(1993)
Mol. Endocrinol.
, vol.7
, pp. 1418-1429
-
-
Smith, D.F.1
-
61
-
-
0027439595
-
Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70
-
Smith, D. F., W. P. Sullivan, T. N. Marion, K. Zaitsu, B. Madden, D. J. McCormick, and D. O. Toft. 1993. Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70. Mol. Cell. Biol. 13:869-876.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 869-876
-
-
Smith, D.F.1
Sullivan, W.P.2
Marion, T.N.3
Zaitsu, K.4
Madden, B.5
McCormick, D.J.6
Toft, D.O.7
-
62
-
-
0028828273
-
Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent
-
Smith, D. F., L. Whitesell, S. C. Nair, S. Chen, V. Prapapanich, and R. A. Rimerman. 1995. Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent. Mol. Cell. Biol. 15:6804-6812.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6804-6812
-
-
Smith, D.F.1
Whitesell, L.2
Nair, S.C.3
Chen, S.4
Prapapanich, V.5
Rimerman, R.A.6
-
63
-
-
0031054517
-
The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase
-
Stancato, L. F., A. M. Silverstein, J. K. Owens-Grillo, Y. H. Chow, R Jove, and W. B. Pratt. 1997. The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase. J. Biol. Chem. 272:4013-4020.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4013-4020
-
-
Stancato, L.F.1
Silverstein, A.M.2
Owens-Grillo, J.K.3
Chow, Y.H.4
Jove, R.5
Pratt, W.B.6
-
64
-
-
0022967572
-
Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus
-
Uehara, Y., M. Hori, T. Takeuchi, and H. Umezawa. 1986. Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus. Mol. Cell. Biol. 6:2198-2206.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 2198-2206
-
-
Uehara, Y.1
Hori, M.2
Takeuchi, T.3
Umezawa, H.4
-
65
-
-
0030997120
-
Hsp90 is obligatory for the heme-regulated eIF-2alpha kinase to acquire and maintain an activatable conformation
-
Erratum, 272: 16068
-
Uma, S., S. D. Hartson, J. J. Chen, and R. L. Matts. 1997. Hsp90 is obligatory for the heme-regulated eIF-2alpha kinase to acquire and maintain an activatable conformation. J. Biol. Chem. 272:11648-11656. (Erratum, 272: 16068.)
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11648-11656
-
-
Uma, S.1
Hartson, S.D.2
Chen, J.J.3
Matts, R.L.4
-
66
-
-
0028033979
-
Multicopy tRNA genes functionally suppress mutations in yeast eIF-2α kinase GCN2: Evidence for separate pathways coupling GCN4 expression to unchanged tRNA
-
Vazquez de Aldana, C. R., R. C. Wek, P. S. Segundo, A. G. Truesdell, and A. G. Hinnebusch. 1994. Multicopy tRNA genes functionally suppress mutations in yeast eIF-2α kinase GCN2: evidence for separate pathways coupling GCN4 expression to unchanged tRNA. Mol. Cell. Biol. 14:7920-7932.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7920-7932
-
-
Vazquez De Aldana, C.R.1
Wek, R.C.2
Segundo, P.S.3
Truesdell, A.G.4
Hinnebusch, A.G.5
-
67
-
-
0028171125
-
eIF-2 kinases: Regulators of general and gene-specific translation initiation
-
Wek, R. C. 1994. eIF-2 kinases: regulators of general and gene-specific translation initiation. Trends Biochem. Sci. 19:491-496.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 491-496
-
-
Wek, R.C.1
-
68
-
-
0024381444
-
Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability
-
Wek, R. C., B. M. Jackson, and A. G. Hinnebusch. 1989. Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability. Proc. Natl. Acad. Sci. USA 86:4579-4583.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 4579-4583
-
-
Wek, R.C.1
Jackson, B.M.2
Hinnebusch, A.G.3
-
69
-
-
0025330827
-
Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression
-
Wek, R. C., M. Ramirez, B. M. Jackson, and A. G. Hinnebusch. 1990. Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression. Mol. Cell. Biol. 10:2820-2831.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 2820-2831
-
-
Wek, R.C.1
Ramirez, M.2
Jackson, B.M.3
Hinnebusch, A.G.4
-
70
-
-
0029006391
-
The histidyl-tRNA synthetase-related sequence in the eIF-2α protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids
-
Wek, S. A., S. Zhu, and R. C. Wek. 1995. The histidyl-tRNA synthetase-related sequence in the eIF-2α protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids. Mol. Cell. Biol. 15:4497-4506.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4497-4506
-
-
Wek, S.A.1
Zhu, S.2
Wek, R.C.3
-
71
-
-
0029973294
-
Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells
-
Whitesell, L., and P. Cook. 1996. Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. Mol. Endocrinol. 10:705-712.
-
(1996)
Mol. Endocrinol.
, vol.10
, pp. 705-712
-
-
Whitesell, L.1
Cook, P.2
-
72
-
-
0028064940
-
Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: Essential role for stress proteins in oncogenic transformation
-
Whitesell, L., E. G. Mimnaugh, B. De Costa, C. E. Myers, and L. M. Neckers. 1994. Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation. Proc. Natl. Acad. Sci. USA 91:8324-8328.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8324-8328
-
-
Whitesell, L.1
Mimnaugh, E.G.2
De Costa, B.3
Myers, C.E.4
Neckers, L.M.5
-
73
-
-
0027291238
-
Heat-shock protein hsp90 governs the activity of pp60v-src kinase
-
Xu, Y., and S. Lindquist. 1993. Heat-shock protein hsp90 governs the activity of pp60v-src kinase. Proc. Natl. Acad. Sci. USA 90:7074-7078.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7074-7078
-
-
Xu, Y.1
Lindquist, S.2
-
74
-
-
0031009879
-
The role of the 90-kDa heat-shock protein and its associated cohorts in stabilizing the heme-regulated eIF-2alpha kinase in reticulocyte lysates during heat stress
-
Xu, Z., J. K. Pal, V. Thulasiraman, H. P. Hahn, J. J. Chen, and R. L. Matts. 1997. The role of the 90-kDa heat-shock protein and its associated cohorts in stabilizing the heme-regulated eIF-2alpha kinase in reticulocyte lysates during heat stress. Eur. J. Biochem. 246:461-470.
-
(1997)
Eur. J. Biochem.
, vol.246
, pp. 461-470
-
-
Xu, Z.1
Pal, J.K.2
Thulasiraman, V.3
Hahn, H.P.4
Chen, J.J.5
Matts, R.L.6
-
75
-
-
0030060955
-
Heat-induced chaperone activity of HSP90
-
Yonehara, M., Y. Minami, Y. Kawata, J. Nagai, and I. Yahara. 1996. Heat-induced chaperone activity of HSP90. J. Biol. Chem. 271:2641-2645.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2641-2645
-
-
Yonehara, M.1
Minami, Y.2
Kawata, Y.3
Nagai, J.4
Yahara, I.5
-
76
-
-
0031806619
-
Molecular mechanism governing heme signaling in yeast: A higher-order complex mediates heme regulation of the transcriptional activator HAP1
-
Zhang, L., A. Hach, and C. Wang. 1998. Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1. Mol. Cell. Biol. 18:3819-3828.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3819-3828
-
-
Zhang, L.1
Hach, A.2
Wang, C.3
-
77
-
-
0029785485
-
Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2
-
Zhu, S., A. Y. Sobolev, and R. C. Wek. 1996. Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2. J. Biol. Chem. 271:24989-24994.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24989-24994
-
-
Zhu, S.1
Sobolev, A.Y.2
Wek, R.C.3
-
78
-
-
0031916835
-
Ribosome-binding domain of eukaryotic initiation factor-2 kinase GCN2 facilitates translation control
-
Zhu, S., and R. C. Wek. 1998. Ribosome-binding domain of eukaryotic initiation factor-2 kinase GCN2 facilitates translation control. J. Biol. Chem. 273:1808-1814.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1808-1814
-
-
Zhu, S.1
Wek, R.C.2
|