Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37

Oncogene

Volumn 22, Issue 57, 2003, Pages 9165-9175

  Nony, Pascale ^a   Gaude, Hélène ^a   Rossel, Mireille ^b   Fournier, Laurence ^a   Rouault, Jean Pierre ^c   Billaud, Marc ^a  

^a FRE 2692   (France)

^b PSL RESEARCH UNIVERSITY   (France)

^c HÔPITAL DEBROUSSE   (France)

Author keywords

Hsp90; LKB1; Peutz jeghers; Tumor suppressor

Indexed keywords

ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; CHAPERONE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; LKB1 GENE; NOVOBIOCIN; PHOSPHOTRANSFERASE; PROTEASOME; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; COMPLEX FORMATION; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PEUTZ JEGHERS SYNDROME; POINT MUTATION; POLYP; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; SIDE EFFECT; TESTIS CANCER;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; BENZOQUINONES; BINDING SITES; CELL CYCLE PROTEINS; CHAPERONINS; DROSOPHILA PROTEINS; ENZYME STABILITY; GENES, TUMOR SUPPRESSOR; HSP90 HEAT-SHOCK PROTEINS; HUMANS; KINETICS; LACTAMS, MACROCYCLIC; MALE; MOLECULAR CHAPERONES; NOVOBIOCIN; PEUTZ-JEGHERS SYNDROME; POINT MUTATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; QUINONES; TESTICULAR NEOPLASMS;

EID: 0346057795     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207179     Document Type: Article

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