Genetic interactions between Hsp90 and the Cdc2 mitotic machinery in the fission yeast Schizosaccharomyces pombe

Molecular and General Genetics

Volumn 261, Issue 2, 1999, Pages 242-250

  Muñoz, M Jesú ^a   Jimenez, J ^a  

^a UNIVERSITY OF MÁLAGA   (Spain)

Author keywords

cdc2; Hsp90; Mitosis; Schizosaccharomyces pombe; swo1

Indexed keywords

ALCOHOL; ASPARTIC ACID; CELL CYCLE PROTEIN; CHAPERONE; CYCLIN DEPENDENT KINASE; FORMAMIDE; GLYCINE; HEAT SHOCK PROTEIN 90; HISTONE H1; POTASSIUM CHLORIDE; PROTEIN TYROSINE KINASE;

ALLELE; AMINO ACID SUBSTITUTION; ANAPHASE; ARTICLE; CELL CYCLE G2 PHASE; CELL MUTANT; CYTOKINESIS; EUKARYOTIC CELL; GENE MUTATION; GENE OVEREXPRESSION; LETHAL GENE; MITOSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SCHIZOSACCHAROMYCES POMBE; TEMPERATURE SENSITIVITY;

ALLELES; AMINO ACID SEQUENCE; CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CULTURE MEDIA; ETHANOL; FORMAMIDES; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; HSP90 HEAT-SHOCK PROTEINS; MITOSIS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEAR PROTEINS; POTASSIUM CHLORIDE; PROTEIN-TYROSINE KINASES; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

EUKARYOTA; SCHIZOSACCHAROMYCES POMBE;

EID: 0032996456     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050963     Document Type: Article

References (42)

1. Aguilera A (1994) Formamide sensitivity: a novel conditional phenotype in yeast. Genetics 136:87-91
2. Alfa C, Fantes P, Hyams P, McLeod M, Warbrick E (1993) Experiments with fission yeast: a laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
3. Aligue R, Akhavan-Niak H, Russell P (1994) A role for Hsp90 in cell cycle control: weel tyrosine kinase activity requires interaction with Hsp90. EMBO J 13:6099-6106
4. Bose S, Weikl T, Bügl H, Buchner J (1996) Chaperone function of Hsp90-associated proteins. Science 247:1715-1717
5. Broek D, Bartlett R, Crawford K, Nurse P (1991) Involvement of p34cdc2 in establishing the dependency of S phase on mitosis. Nature 349:388-93
6. Chang F, Nurse P (1993) Finishing the cell cycle: control of mitosis and cytokinesis in fission yeast. Trends Genet 9:333-335
7. Chen C, Chen Y, Day K, Cehn P, Riley DJ, Lee W (1996) A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock. Mol Cell Biol 16:4691-4699
8. Dai K, Kobayashi R, Beach D (1996) Physical interaction of mammalian CDC37 with CDK4. J Biol Chem 271:22030-22034
9. Demand J, Luders J, Hohfeld J (1998) The carboxy-terminal domain of Hsc70 provides binding sites for a distinct set of chaperone cofactors. Mol Cell Biol 18:2023-2028
10. Dittmar KD, Hutchison KA, Owens-Grillo JK, Pratt WB (1996) Reconstitution of the steroid receptor hsp90 heterocomplex assembly system of rabbit reticulocyte lysate. J Biol Chem 271:12833-12839
11. Fantes P (1981) Isolation of cell size mutants of a fission yeast by a new selective method. J Bacteriol 146:746-754
12. Freeman BC, Toft DO, Morimoto R (1996) Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23. Science 247:1718-1720
13. Gerber MR, Farrell A, Deshaies RJ, Herskowitz I, Morgan DO (1995) Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins. Proc Natl Acad Sci USA 92:4651-4655
14. Gould KL, Nurse P, 1989 Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature 342:39-45
15. Jimenez J, Alphey L, Nurse P, Glover DG (1990) Complementation of fission yeast cdc2ts and cdc25ts mutants identifies two cell cycle genes from Drosophila: a cdc2 homologue and string. EMBO J 9:3565-3571
16. Jimenez J, Oballe J (1994) Ethanol-hypersensitive and ethanol-dependent cdc- mutants in Schizosaccharomyces pombe. Mol Gen Genet 245:86-95
17. Johnson BD, Schumacher RJ, Ross ED, Toft DO (1998) Hop modulates Hsp70/Hsp90 interactions in protein folding. J Biol Chem 273:3679-3686
18. Johnson JL, Toft DO (1994) A novel chaperone complex for steroid receptors involving heat shock proteins, immunophilins, and p23. J Biol Chem 269:24989-93
19. Labib K, Craven RA, Crawford K, Nurse P (1995) Dominant mutants identify new roles for p34cdc2 in mitosis. EMBO J 14:2155-2165
20. Lundgren K, Walworth N, Booher R, Dembiski M, Kirschner M, Beach D (1991) mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell 64:1111-1122
21. Mahony D, Parry DA, Lees E (1998) Active cdk6 complexes are predominantly nuclear and represent only a minority of the cdk6 in T cells. Oncogene 16:603-611
22. Maundrell K (1993) Thiamine-repressible expression vectors pREP and pRIP for fission yeast. Gene 123:127-130
23. McGowan C, Russell P (1993) Human weel kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15. EMBO J 12:75-85
24. Miyata Y, Yahara I (1995) Interaction between casein kinase II and the 90-kDa stress protein, HSP90. Biochemistry 34:8123-8129
25. Moreno S, Klar A, Nurse P (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194:795-823
26. Nasmyth K, Nurse P (1981) Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet 182:119-124
27. Nathan DF, Vos MH, Lindqnist S (1997) In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone. Proc Natl Acd Sci USA 94:12949-12956
28. Nurse P (1990) Universal control mechanism regulating onset of M-phase. Nature 344:503-508
29. Nurse P, Thuriaux P, Nasmyth K (1976) Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet 146:167-178
30. Pratt WB (1997) The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase. Annu Rev Pharmacol Toxicol 37:297-326
31. Prentice HL (1992) High efficiency transformation of Schizosaccharomyces pombe by electroporation. Nucleic Acids Res 20:621
32. Purdom CH (1993) Genetics and fish breeding. Chapman and Hall, London, pp 192-222
33. Russell P, Nurse P (1987) Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell 49:559-567
34. Sazer S, Sherwood SW (1990) Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast. J Cell Sci 97:509-516
35. Shue G, Kohtz DS (1994) Structural and functional aspects of basic helix-loop-helix protein folding by heat-shock protein 90. J Biol Chem 269:2707-2711
36. Stepanova L, Leng X, Parker SB, Harper JW (1996) Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4. Genes Dev 10:1491-1502
37. Wartmann M, Davis RJ (1994) The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex. J Biol Chem 269:6695-6701
38. Weisman R, Creanor J, Fantes P (1996) A multicopy suppressor of a cell cycle defect in S pombe encodes a heat shock-induced 40 kDa cyclophilin-like protein. EMBO J 15:447-456
39. Wright A, Maundrell K, Heyer WD, Beach D, Nurse P (1986) Vectors for the construction of gene banks and the integration of cloned genes in Schizosaccharomyces pombe. Plasmid 15:156-158
40. Xu Y, Lindquist S (1993) Heat-shock protein hsp90 governs the activity of pp60v-src kinase. Proc Natl Acad Sci USA 90:7074-7078
41. Yaffe MB, Schutkowski M, Shen M, Zhou XZ, Stukenberg PT, Rahfeld JU, Xu J, Kuang J, Kirschner MW, Fischer G, Cantley LC, Lu KP (1997) Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science 278:1957-60
42. Yaglom JA, Goldberg AL, Finley D, Sherman MY (1996) The molecular chaperone Ydj1 is required for the p34CDC28-dependent phosphorylation of the cyclin Cln3 that signals its degradation. Mol Cell Biol 16:3679-84