Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors

Leukemia

Volumn 16, Issue 8, 2002, Pages 1535-1540

  Minami, Y ^a   Kiyoi, H ^a   Yamamoto, Y ^a   Yamamoto, K ^a   Ueda, R ^b   Saito, H ^a,c   Naoe, T ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^c NATIONAL HOSPITAL ORGANIZATION NAGOYA MEDICAL CENTER   (Japan)

Author keywords

Apoptosis; FLT3; Herbimycin A; Hsp90; Leukemia

Indexed keywords

ANSAMYCIN DERIVATIVE; CHAPERONE; FLT3 LIGAND; HEAT SHOCK PROTEIN 90; HERBIMYCIN A; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE B; RADICICOL; STAT PROTEIN; TYROSINE KINASE RECEPTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL TRANSFORMATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; GENE DUPLICATION; GENE MUTATION; GROWTH INHIBITION; IMMUNOPRECIPITATION; LEUKEMIA CELL; LEUKOCYTOSIS; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TANDEM REPEAT; WILD TYPE;

EID: 0036050018     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402558     Document Type: Article

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