-
1
-
-
0021593913
-
Biological implications of consistent chromosome rearrangements in leukemia and lymphoma
-
Rowley, J. D. Biological implications of consistent chromosome rearrangements in leukemia and lymphoma. Cancer Res., 44, 3159-3168 (1984).
-
(1984)
Cancer Res.
, vol.44
, pp. 3159-3168
-
-
Rowley, J.D.1
-
2
-
-
0025746321
-
t(8:21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene
-
Miyoshi, H., Shimizu, K., Kozu, T., Museki, N., Kaneko, Y. and Ohki, M. t(8:21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene. AML1. Proc. Natl. Acad. Sci. USA, 88, 10431-10434 (1991).
-
(1991)
AML1. Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10431-10434
-
-
Miyoshi, H.1
Shimizu, K.2
Kozu, T.3
Museki, N.4
Kaneko, Y.5
Ohki, M.6
-
3
-
-
0026757174
-
Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to drosophila segmentation gene, runt
-
Erickson, P., Gao, J., Chang, K.-S., Look, T., Whisenant, E., Raimondi, S., Lasher, R., Trujillo, J., Rowley, J. and Drabkin, H. Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt. Blood, 80, 1825-1831 (1992).
-
(1992)
Blood
, vol.80
, pp. 1825-1831
-
-
Erickson, P.1
Gao, J.2
Chang, K.-S.3
Look, T.4
Whisenant, E.5
Raimondi, S.6
Lasher, R.7
Trujillo, J.8
Rowley, J.9
Drabkin, H.10
-
4
-
-
0027265454
-
Junctions of the AML1/MTG8 (ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction
-
Kozu, T., Miyoshi, H., Shimizu, K., Maseki, N., Kaneko, Y., Asou, H., Kamada, N. and Ohki, M. Junctions of the AML1/MTG8 (ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction. Blood, 82, 1270-1276 (1993).
-
(1993)
Blood
, vol.82
, pp. 1270-1276
-
-
Kozu, T.1
Miyoshi, H.2
Shimizu, K.3
Maseki, N.4
Kaneko, Y.5
Asou, H.6
Kamada, N.7
Ohki, M.8
-
5
-
-
0027218725
-
The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript
-
Miyoshi, H., Kozu, T., Shimizu, K., Enomoto, K., Maseki, N., Kaneko, Y., Kamada, N. and Ohki, M. The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript. EMBO J., 12, 2715-2721 (1993).
-
(1993)
EMBO J.
, vol.12
, pp. 2715-2721
-
-
Miyoshi, H.1
Kozu, T.2
Shimizu, K.3
Enomoto, K.4
Maseki, N.5
Kaneko, Y.6
Kamada, N.7
Ohki, M.8
-
6
-
-
0029100157
-
Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia
-
Miyoshi, H., Ohira, M., Shimizu, K., Mitani, K., Hirai, H., Imai, T., Yokoyama, K., Soeda, E. and Ohki, M. Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia. Nucleic Acids Res., 23, 2762-2769 (1995).
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 2762-2769
-
-
Miyoshi, H.1
Ohira, M.2
Shimizu, K.3
Mitani, K.4
Hirai, H.5
Imai, T.6
Yokoyama, K.7
Soeda, E.8
Ohki, M.9
-
7
-
-
0028925282
-
The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation
-
Meyers, S., Lenny, N. and Hiebert, S. W. The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation. Mol. Cell. Biol., 15, 1974-1982 (1995).
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1974-1982
-
-
Meyers, S.1
Lenny, N.2
Hiebert, S.W.3
-
8
-
-
0029616633
-
The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B
-
Frank, R., Zhang, J., Uchida, H., Meyers, S., Hiebert, S. W. and Nimer, S. D. The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B. Oncogene, 11, 2667-2674 (1995).
-
(1995)
Oncogene
, vol.11
, pp. 2667-2674
-
-
Frank, R.1
Zhang, J.2
Uchida, H.3
Meyers, S.4
Hiebert, S.W.5
Nimer, S.D.6
-
9
-
-
0028786125
-
Functional domains of the t(8;21) fusion protein, AML-1/ETO
-
Lenny, N., Meyers, S. and Hiebert, S. W. Functional domains of the t(8;21) fusion protein, AML-1/ETO. Oncogene, 11, 1761-1769 (1995).
-
(1995)
Oncogene
, vol.11
, pp. 1761-1769
-
-
Lenny, N.1
Meyers, S.2
Hiebert, S.W.3
-
10
-
-
0031972701
-
The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-α, inhibits C/EBP-α-dependent transcription, and blocks granulocytic differentiation
-
Westendorf, J. J., Yaniamoto, C. M., Lenny, N., Downing, J. R., Selsted, M. E. and Hiebert, S. W. The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-α, inhibits C/EBP-α-dependent transcription, and blocks granulocytic differentiation. Mol. Cell. Biol., 18, 322-333 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 322-333
-
-
Westendorf, J.J.1
Yaniamoto, C.M.2
Lenny, N.3
Downing, J.R.4
Selsted, M.E.5
Hiebert, S.W.6
-
11
-
-
0029859199
-
Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8:21) fusion protein may contribute to leukemogenesis
-
Rhoades, K. L., Hetherington, C. J., Rowley, J. D., Hiebert, S. W., Nucifora, G., Tenen, D. G. and Zhang, D.-E. Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8:21) fusion protein may contribute to leukemogenesis. Proc. Natl. Acad. Sci. USA, 93, 11895-11900 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11895-11900
-
-
Rhoades, K.L.1
Hetherington, C.J.2
Rowley, J.D.3
Hiebert, S.W.4
Nucifora, G.5
Tenen, D.G.6
Zhang, D.-E.7
-
12
-
-
0030445949
-
The AML1/ETO fusion protein activates transcription of BCL-2
-
Klampfer, L., Zhang, J., Zelenetz, A. O., Uchida, H. and Nimer, S. D. The AML1/ETO fusion protein activates transcription of BCL-2. Proc. Natl. Acad. Sci. USA, 93, 14059-14064 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14059-14064
-
-
Klampfer, L.1
Zhang, J.2
Zelenetz, A.O.3
Uchida, H.4
Nimer, S.D.5
-
13
-
-
0028267241
-
The ETO portion of acute myeloid leukemia t(8:21) fusion transcript encodes a highly evolutionary conserved, putative transcription factor
-
Erickson, P. F., Robinson, M., Owens, G. and Drabkin, H. A. The ETO portion of acute myeloid leukemia t(8:21) fusion transcript encodes a highly evolutionary conserved, putative transcription factor. Cancer Res., 54, 1782-1786 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 1782-1786
-
-
Erickson, P.F.1
Robinson, M.2
Owens, G.3
Drabkin, H.A.4
-
14
-
-
0028990261
-
Identification of two transcripts of AML1/ ETO-fused gene in t(8;21) leukemic cells and expression of wild-type ETO gene in hematopoietic cells
-
Era, T., Asou, N., Kunisada, T., Yamasaki, H., Asou, H., Kamada, N., Nishikawa, S.-I., Yamaguchi, K. and Takatsuki, K. Identification of two transcripts of AML1/ ETO-fused gene in t(8;21) leukemic cells and expression of wild-type ETO gene in hematopoietic cells. Genes Chromosom. Cancer, 13, 25-33 (1995).
-
(1995)
Genes Chromosom. Cancer
, vol.13
, pp. 25-33
-
-
Era, T.1
Asou, N.2
Kunisada, T.3
Yamasaki, H.4
Asou, H.5
Kamada, N.6
Nishikawa, S.-I.7
Yamaguchi, K.8
Takatsuki, K.9
-
16
-
-
0031858792
-
Tumourigenicity of MTG8, a leukaemia-related gene, in concert with v-Ha-ras gene in BALB/3T3 cells
-
Sueoka, E., Sueoka, N., Okabe, S., Komori, A., Suganuma, M., Kozu, T. and Fujiki, H. Tumourigenicity of MTG8, a leukaemia-related gene, in concert with v-Ha-ras gene in BALB/3T3 cells. Br. J. Haematol., 101, 737-742 (1998).
-
(1998)
Br. J. Haematol.
, vol.101
, pp. 737-742
-
-
Sueoka, E.1
Sueoka, N.2
Okabe, S.3
Komori, A.4
Suganuma, M.5
Kozu, T.6
Fujiki, H.7
-
17
-
-
0027135501
-
The function of heat-shock proteins in stress tolerance: Degradation and reactivation of damaged proteins
-
Parsell, D. A. and Lindquist, S. The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins. Annu. Rev. Genet., 21, 437-496 (1993).
-
(1993)
Annu. Rev. Genet.
, vol.21
, pp. 437-496
-
-
Parsell, D.A.1
Lindquist, S.2
-
18
-
-
0025817842
-
Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8:21 chromosome translocation
-
Asou, H., Tashiro, S., Hamamoto, K., Otsuji, A., Kita, K. and Kamuda, N. Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8:21 chromosome translocation. Blood, 77, 2031-2036 (1991).
-
(1991)
Blood
, vol.77
, pp. 2031-2036
-
-
Asou, H.1
Tashiro, S.2
Hamamoto, K.3
Otsuji, A.4
Kita, K.5
Kamuda, N.6
-
19
-
-
0028962455
-
Establishment of a myeloid leukemic cell line (SKNO-1) from a patient with t(8;21) who acquired monosomy 17 during disease progression
-
Matozaki, S., Nakagawa, T., Kawaguchi, R., Aozaki, R., Tsutsumi, M., Muruyama, T., Koizumi, T., Nishimura, R., Isobe, T. and Chihara, K. Establishment of a myeloid leukemic cell line (SKNO-1) from a patient with t(8;21) who acquired monosomy 17 during disease progression. Br. J. Haematol., 89, 805-811 (1995).
-
(1995)
Br. J. Haematol.
, vol.89
, pp. 805-811
-
-
Matozaki, S.1
Nakagawa, T.2
Kawaguchi, R.3
Aozaki, R.4
Tsutsumi, M.5
Muruyama, T.6
Koizumi, T.7
Nishimura, R.8
Isobe, T.9
Chihara, K.10
-
20
-
-
0027423418
-
Identification of an oncoprotein-and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
-
Hibi, M., Lin, A., Smeal, T., Minden, A. and Karin, M. Identification of an oncoprotein-and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev., 7, 2135-2148 (1993).
-
(1993)
Genes Dev.
, vol.7
, pp. 2135-2148
-
-
Hibi, M.1
Lin, A.2
Smeal, T.3
Minden, A.4
Karin, M.5
-
21
-
-
0024558784
-
Acid and base hydrolysis of phosphoproteins bound to immobilon facilitates analysis of phosphoamino acids in gel-fractionated proteins
-
Kamps, M. P. and Sefton, B. M. Acid and base hydrolysis of phosphoproteins bound to immobilon facilitates analysis of phosphoamino acids in gel-fractionated proteins. Anal. Biochem., 176, 22-27 (1989).
-
(1989)
Anal. Biochem.
, vol.176
, pp. 22-27
-
-
Kamps, M.P.1
Sefton, B.M.2
-
22
-
-
0027221568
-
γ-Phosphate-linked ATP-sepharose for the affinity purification of protein kinases. Rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase
-
Haystead, C. M. M., Gregory, P., Sturgill, T. W. and Haystead, T. A. J. γ-Phosphate-linked ATP-Sepharose for the affinity purification of protein kinases. Rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase. Eur. J. Biochem., 214, 459-467 (1993).
-
(1993)
Eur. J. Biochem.
, vol.214
, pp. 459-467
-
-
Haystead, C.M.M.1
Gregory, P.2
Sturgill, T.W.3
Haystead, T.A.J.4
-
23
-
-
0024358172
-
Sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel
-
Kameshita, I. and Fujisawa, H. A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel. Anal. Biochem., 183, 139-143 (1989).
-
(1989)
Anal. Biochem.
, vol.183
, pp. 139-143
-
-
Kameshita, I.1
Fujisawa, H.A.2
-
24
-
-
0027272945
-
Tumor promotion by inhibitors of protein phosphatases 1 and 2A: The okadaic acid class of compounds
-
Fujiki, H. and Suganuma, M. Tumor promotion by inhibitors of protein phosphatases 1 and 2A: the okadaic acid class of compounds. Adv. Cancer Res., 61, 143-194 (1993).
-
(1993)
Adv. Cancer Res.
, vol.61
, pp. 143-194
-
-
Fujiki, H.1
Suganuma, M.2
-
25
-
-
0023224123
-
Nucleolide sequence of a cDNA for a member of the human 90 kDa heat-shock protein family
-
Rebbe, N. F., Ware, J., Bertina, R. M. Modrich P. and Stafford, D. W. Nucleolide sequence of a cDNA for a member of the human 90 kDa heat-shock protein family. Gene, 53, 235-245 (1987).
-
(1987)
Gene
, vol.53
, pp. 235-245
-
-
Rebbe, N.F.1
Ware, J.2
Bertina, R.M.3
Modrich, P.4
Stafford, D.W.5
-
26
-
-
0031444238
-
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
-
Prodromou, C., Poe, S. M. O'Brien, R., Ladbury, J. E., Piper, P. W. and Pearl, L. H. Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone. Cell, 90, 65-75 (1997).
-
(1997)
Cell
, vol.90
, pp. 65-75
-
-
Prodromou, C.1
Poe, S.M.2
O'Brien, R.3
Ladbury, J.E.4
Piper, P.W.5
Pearl, L.H.6
-
27
-
-
0029986957
-
DHAF-1, a novel protein that binds an essential region in a deformed response element
-
Gross, C. T. and McGinnins, W. DHAF-1, a novel protein that binds an essential region in a Deformed response element. EMBO J., 15, 1961-1970 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 1961-1970
-
-
Gross, C.T.1
McGinnins, W.2
-
28
-
-
0030761474
-
Significance of MTG8 in leukemogenesis
-
Kozu, T., Komori, A., Sueoka, E., Fujiki, H., Kaneko, Y., Matsui, T., Uehara, T., Seino, Y. and Ishii, M. Significance of MTG8 in leukemogenesis. Leukemia, 11(S3), 297-298 (1997).
-
(1997)
Leukemia
, vol.11
, Issue.S3
, pp. 297-298
-
-
Kozu, T.1
Komori, A.2
Sueoka, E.3
Fujiki, H.4
Kaneko, Y.5
Matsui, T.6
Uehara, T.7
Seino, Y.8
Ishii, M.9
-
29
-
-
0031844689
-
The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein
-
Lutterbach, B., Sun, D., Schuetz, S. D. and Hiebert, S. W. The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein. Mol. Cell. Biol., 18, 3604-3611 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3604-3611
-
-
Lutterbach, B.1
Sun, D.2
Schuetz, S.D.3
Hiebert, S.W.4
-
30
-
-
0031895351
-
The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors
-
Pratt, W. B. The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors. Proc. Soc. Exp. Biol. Med., 217, 420-434 (1998).
-
(1998)
Proc. Soc. Exp. Biol. Med.
, vol.217
, pp. 420-434
-
-
Pratt, W.B.1
-
31
-
-
0029963674
-
Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90
-
Sehneider, C., Sepp-Lorenzino, L., Nimmesgern, E., Ouerfelli, O., Danishefsky, S., Rosen, N. and Hartl, F. U. Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90. Proc. Natl. Acad. Sci. USA, 93, 14536-14541 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14536-14541
-
-
Sehneider, C.1
Sepp-Lorenzino, L.2
Nimmesgern, E.3
Ouerfelli, O.4
Danishefsky, S.5
Rosen, N.6
Hartl, F.U.7
-
32
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent
-
Stebbins, C. E., Russo, A. A., Schneider, C., Rosen, N., Hartl, F. U. and Pavletich, N. P. Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell. 89, 239-250 (1997).
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
Rosen, N.4
Hartl, F.U.5
Pavletich, N.P.6
-
34
-
-
0029813620
-
Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway
-
Schulte, T. W., Blagosklonny, M. V., Romanova, L., Mushinski, J. F., Monia, B. P. Johnston, J. F., Nguyen, P., Trepel, J. and Neckers, L. M. Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway. Mol. Cell. Biol., 16, 5839-5845 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5839-5845
-
-
Schulte, T.W.1
Blagosklonny, M.V.2
Romanova, L.3
Mushinski, J.F.4
Monia, B.P.5
Johnston, J.F.6
Nguyen, P.7
Trepel, J.8
Neckers, L.M.9
-
35
-
-
0029973294
-
Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells
-
Whitesell, L. and Cook, P. Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. Mol. Endocrinol., 10, 705-712 (1996).
-
(1996)
Mol. Endocrinol.
, vol.10
, pp. 705-712
-
-
Whitesell, L.1
Cook, P.2
-
36
-
-
0031883569
-
The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8 (ETO/ CDR) family, MTGR1
-
Kitabayashi, I., Ida, K., Morohoshi, F., Yokoyama, A., Mitsuhashi, N., Shimizu, K., Nomura, N., Hayashi, Y. and Ohki, M. The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8 (ETO/ CDR) family, MTGR1. Mol. Cell. Biol., 18, 846-858 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 846-858
-
-
Kitabayashi, I.1
Ida, K.2
Morohoshi, F.3
Yokoyama, A.4
Mitsuhashi, N.5
Shimizu, K.6
Nomura, N.7
Hayashi, Y.8
Ohki, M.9
-
37
-
-
0032101547
-
The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8 (ETO) family
-
Gamou, T., Kitamura, E., Hosoda, F., Shimizu, K., Shinohara, K., Hayashi, Y., Nagase, T., Yokoyama, Y. and Ohki, M. The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8 (ETO) family. Blood, 91, 4028-4037 (1998).
-
(1998)
Blood
, vol.91
, pp. 4028-4037
-
-
Gamou, T.1
Kitamura, E.2
Hosoda, F.3
Shimizu, K.4
Shinohara, K.5
Hayashi, Y.6
Nagase, T.7
Yokoyama, Y.8
Ohki, M.9
|