SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex

Molecular Cell

Volumn 4, Issue 1, 1999, Pages 21-33

  Kitagawa, Katsumi ^a   Skowyra, Dorota ^b   Elledge, Stephen J ^b   Harper, J Wade ^b   Hieter, Philip ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CENTROMERE; ENZYME ANALYSIS; FUNGAL GENETICS; GENE MUTATION; GENOTYPE; NONHUMAN; PHENOTYPE; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0033166694     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80184-7     Document Type: Article

References (50)

1. Bai, C., Sen, P., Hofmann, K., Ma, L., Goebl, M., Harper, J.W., and Elledge, S.J. (1996). SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box. Cell 86, 263-274.
2. Boeke, J.D., Trueheart, J., Natsoulis, G., and Fink, G.R. (1987). 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154, 164-175.
3. Brown, J.L., Jaquenoud, M., Gulli, M.P., Chant, J., and Peter, M. (1997). Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev. 11, 2972-2982.
4. Chen, M.X., McPartlin, A.E., Brown, L., Chen, Y.H., Barker, H.M., and Cohen, P.T. (1994). A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus. EMBO J. 13, 4278-4290.
5. Connelly, C., and Hieter, P. (1996). Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression. Cell 86, 275-285.
6. Doheny, K.F., Sorger, P.K., Hyman, A.A., Tugendreich, S., Spencer, F., and Hieter, P. (1993). Identification of essential components of the S. cerevisiae kinetochore. Cell 73, 761-774.
7. Feldman, R.M., Correll, C.C., Kaplan, K.B., and Deshaies, R.J. (1997). A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91, 221-230.
8. Fitzgerald-Hayes, M., Clarke, L., and Carbon, J. (1982). Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs. Cell 29, 235-244.
9. Elledge, S.J., and Harper, J.W. (1998). Proteolysis in cell cycle control and cancer. Biochem. Biophys. Acta 1377, M61-M70.
10. Goh, P.Y., and Kilmartin, J.V. (1993). NDC10: A gene involved in chromosome segregation in Saccharomyces cerevisiae. J. Cell Biol. 121, 503-512.
11. Hegemann, J.H., Shero, J.H., Cottarel, G., Philippsen, P., and Hieter, P. (1988). Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae. Mol. Cell. Biol. 8, 2523-2535.
12. Henchoz, S., Chi, Y., Catarin, B., Herskowitz, I., Deshaies, R.J., and Peter, M. (1997). Phosphorylation-and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev. 11, 3046-3060.
13. Hieter, P., Mann, C., Snyder, M., and Davis, R.W. (1985a). Mitotic stability of yeast chromosomes: A colony color assay that measures nondisjunction and chromosome loss. Cell 40, 381-392.
14. Hieter, P., Pridmore, D., Hegemann, J.H., Thomas, M., Davis, R.W., and Philippsen, P. (1985b). Functional selection and analysis of yeast centromeric DNA. Cell 42, 913-921.
15. Ito, H., Fukuda, Y., Murata, K., and Kimura, A. (1983). Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168.
16. grr1 complex. EMBO J. 17, 5360-5373.
17. Jiang, W., Lechner, J., and Carbon, J. (1993). Isolation and characterization of a gene (CBF2) specifying a protein component of the budding yeast kinetochore. J. Cell Biol. 121, 513-519.
18. Kaiser, P., Sia, R.A., Bardes, E.G., Lew, D.J., and Reed, S.I. (1998). Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1. Genes Dev. 12, 2587-2597.
19. Kamura, T., Koepp, D.M., Conrad, M.N., Skowyra, D., Moreland, R.J., Iliopoulos, O., Lane, W.S., Kaelin, W.G., Jr., Elledge, S.J., ConaWay, R.C., et al. (1999). Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284, 657-661.
20. Kaplan, K.B., Hyman, A.A., and Sorger, P.K. (1997). Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation. Cell 91, 491-500.
21. Koshland, D., and Hieter, P. (1987). Visual assay for chromosome ploidy. Methods Enzymol. 155, 351-372.
22. Lamb, J.R., Michaud, W.A., Sikorski, R.S., and Hieter, P.A. (1994). Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis. EMBO J. 13, 4321-4328.
23. Lechner, J. (1994). A zinc finger protein, essential for chromosome segregation, constitutes a putative DNA binding subunit of the Saccharomyces cerevisiae kinetochore complex, Cbf3. EMBO J. 13, 5203-5211.
24. Lechner, J., and Carbon, J. (1991). A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64, 717-725.
25. Lorenz, M.C., Muir, R.S., Lim, E., McElver, J., Weber, S.C., and Heitman, J. (1995). Gene disruption with PCR products in Saccharomyces cerevisiae. Gene 158, 113-117.
26. Maniatis, T. (1999). A ubiquitin ligase complex essential for the NF-kappab, Wnt/Wingless, and Hedgehog signaling pathways. Genes Dev. 13, 505-510.
27. Meluh, P.B., and Koshland, D. (1997). Budding yeast centromere composition and assembly as revealed by in vivo cross-linking. Genes Dev. 11, 3401-3412.
28. Meluh, P.B., and Koshland, D. (1995). Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol. Biol. Cell 6, 793-807.
29. Meluh, P.B., Yang, P., Glowczewski, L., Koshland, D., and Smith, M.M. (1998). Cse4p is a component of the core centromere of Saccharomyces cerevisiae. Cell 94, 607-613.
30. Muhlrad, D., Hunter, R., and Parker, R. (1992). A rapid method for localized mutagenesis of yeast genes. Yeast 8, 79-82.
31. Murphy, T.D., and Karpen, G.H. (1998). Centromeres take flight: Alpha satellite and the quest for the human centromere. Cell 93, 317-320.
32. Newman, T., de Bruijn, F.J., Green, P., Keegstra, K., Kende, H., McIntosh, L., Ohlrogge, J., Raikhel, N., Somerville, S., Thomashow, M., et al. (1994). Genes galore: A summary of methods for accessing results from large-scale partial sequencing of anonymous Arabidopsis cDNA clones. Plant Physiol. 106, 1241-1255.
33. Nugroho, T.T., and Mendenhall, M.D. (1994). An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells. Mol. Cell. Biol. 14, 3320-3328.
34. Pangilinan, F., and Spencer, F. (1996). Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast. Mol. Biol. Cell 7, 1195-1208.
35. Patton, E.E., Willems, A.R., Sa, D., Kuras, L., Thomas, D., Craig, K.L., and Tyers, M. (1998a). Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Genes Dev. 12, 692-705.
36. Patton, E.E., Willems, A.R., and Tyers, M. (1998b). Combinatorial control in ubiquitin-dependent proteolysis: Don't Skp the F-box hypothesis. Trends Genet. 14, 236-243.
37. Rose, M.D., Winston, F., and Hieter, P. (1990). Methods in Yeast Genetics (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press).
38. Saitoh, H., Tomkiel, J., Cooke, C.A., Ratrie, H.D., Maurer, M., RothField, N.F., and Earnshaw, W.C. (1992). CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70, 115-125.
39. Schwob, E., Bohm, T., Mendenhall, M.D., and Nasmyth, K. (1994). The B-type cyclin kinase inhibitor p40SIc1 controls the G1 to S transition in S. cerevisiae. Cell 79, 233-244. Erratum: Cell 84(1), 1996.
40. Schwob, E., Bohm, T., Mendenhall, M.D., and Nasmyth, K. (1994). The B-type cyclin kinase inhibitor p40Sic1 controls the G1 to S transition in S. cerevisiae. Cell 79, 233-244. Erratum: Cell 84(1), 1996.
41. Sikorski, R.S., and Hieter, P. (1989). A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122, 19-27.
42. Skowyra, D., Craig, K.L., Tyers, M., Elledge, S.J., and Harper, J.W. (1997). F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91, 209-219.
43. GRR1 and Rbx1. Science 284, 662-665.
44. Sorger, P.K., Doheny, K.F., Hieter, P., Kopski, K.M., Huffaker, T.C., and Hyman, A.A. (1995). Two genes required for the binding of an essential Saccharomyces cerevisiae kinetochore complex to DNA. Proc. Natl. Acad. Sci. USA 92, 12026-12030.
45. Stemmann, O., and Lechner, J. (1996). The Saccharomyces cerevisiae kinetochore contains a cyclin-CDK complexing homologue, as identified by in vitro reconstitution. EMBO J. 15, 3611-3620.
46. Strunnikov, A.V., Kingsbury, J., and Koshland, D. (1995). CEP3 encodes a centromere protein of Saccharomyces cerevisiae. J. Cell Biol. 128, 749-760.
47. Takahashi, K., Paladini, R.D., and Coulombe, P.A. (1995). Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms. J. Biol. Chem. 270, 18581-18592.
48. Warburton, P.E., Cooke, C.A., Bourassa, S., Vafa, O., Sullivan, B.A., Stetten, G., Gimelli, G., Warburton, D., Tyler-Smith, C., Sullivan, K.F., et al. (1997). Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Curr. Biol. 7, 901-904.
49. Wiens, G.R., and Sorger, P.K. (1998). Centromeric chromatin and epigenetic effects in kinetochore assembly. Cell 93, 313-316.
50. Yoon, H.J., and Carbon, J. (1995). Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme. Mol. Cell. Biol. 15, 4835-4842.