Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome

EMBO Journal

Volumn 17, Issue 23, 1998, Pages 6879-6887

  Loo, Melinda A ^a   Jensen, Timothy J ^a   Cui, Liying ^a   Hou, Yue Xian ^a   Chang, Xiu Bao ^a   Riordan, John R ^a  

^a MAYO CLINIC   (United States)

Author keywords

Ansamycin; CFTR; ER degradation; Hsp90; Proteasome

Indexed keywords

CALNEXIN; GELDANAMYCIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HERBIMYCIN A; OLIGOSACCHARIDE; PROTEASOME; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0032401771     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.23.6879     Document Type: Article

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