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Volumn 14, Issue 11, 2013, Pages 22274-22330

The NO/ONOO-cycle as the central cause of heart failure

Author keywords

Ca2+ receptors; Free radicals; Inflammatory biochemistry; Mitochondrial dysfunction; Nitrosative stress; Peroxynitrite; Reactive oxygen nitrogen species; Tetrahydrobiopterin oxidation

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADIPONECTIN; CALCIUM; CALPAIN; CARDIOLIPIN; CYTOKINE; ENDOTHELIN 1; FREE RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL PROTEIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SUPEROXIDE; TETRAHYDROBIOPTERIN;

EID: 84887541654     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms141122274     Document Type: Review
Times cited : (45)

References (284)
  • 1
    • 84887527493 scopus 로고    scopus 로고
    • Pulmonary hypertension is a probable NO/ONOO-cycle disease: A review
    • 742418:1-742418:27
    • Pall, M. L. Pulmonary hypertension is a probable NO/ONOO-cycle disease: A review. ISRN Hypertens. 2013, 2013, 742418: 1-742418: 27.
    • (2013) ISRN Hypertens. , vol.2013
    • Pall, M.L.1
  • 2
    • 77957915088 scopus 로고    scopus 로고
    • Multiple Chemical Sensitivity: Toxicological Questions and Mechanisms
    • In, 3rd ed.; Ballantyne, B., Marrs, T.C., Syversen, T., Eds.; John Wiley & Sons: London, UK
    • Pall, M. L. Multiple Chemical Sensitivity: Toxicological Questions and Mechanisms. In General and Applied Toxicology, 3rd ed.; Ballantyne, B., Marrs, T. C., Syversen, T., Eds.; John Wiley & Sons: London, UK, 2009; pp. 2303-2352.
    • (2009) General and Applied Toxicology , pp. 2303-2352
    • Pall, M.L.1
  • 4
    • 37549019342 scopus 로고    scopus 로고
    • The NO/ONOO-cycle as the etiological mechanism of tinnitus
    • Pall, M. L.; Bedient, S. A. The NO/ONOO-cycle as the etiological mechanism of tinnitus. Int. Tinnitus J. 2007, 13, 99-104.
    • (2007) Int. Tinnitus J. , vol.13 , pp. 99-104
    • Pall, M.L.1    Bedient, S.A.2
  • 5
    • 84887538696 scopus 로고    scopus 로고
    • Teufelskreis NO/ONOO--Zyklus, oxidaver Stress, mitochondriale, inflammatorische und neurologische Dysfunktion
    • Pall, M. L. Teufelskreis NO/ONOO--Zyklus, oxidaver Stress, mitochondriale, inflammatorische und neurologische Dysfunktion. Umw. Med. Ges. 2010, 23, 281-293.
    • (2010) Umw. Med. Ges. , vol.23 , pp. 281-293
    • Pall, M.L.1
  • 6
    • 77957915942 scopus 로고    scopus 로고
    • How can we cure NO/ONOO-cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others
    • Feb/Mar
    • Pall, M. L. How can we cure NO/ONOO-cycle diseases? Approaches to curing chronic fatigue syndrome/myalgic encephalomyelitis, fibromyalgia, multiple chemical sensitivity, Gulf War syndrome and possibly many others. Townsend Lett. 2010, Feb/Mar, 75-84.
    • (2010) Townsend Lett. , pp. 75-84
    • Pall, M.L.1
  • 7
    • 0034013955 scopus 로고    scopus 로고
    • Elevated, sustained peroxynitrite levels as the cause of chronic fatigue syndrome
    • Pall, M. L. Elevated, sustained peroxynitrite levels as the cause of chronic fatigue syndrome. Med. Hypotheses 2000, 54, 115-125.
    • (2000) Med. Hypotheses , vol.54 , pp. 115-125
    • Pall, M.L.1
  • 8
    • 0036720685 scopus 로고    scopus 로고
    • NMDA sensitization and stimulation by peroxynitrite, nitric oxide and organic solvents as the mechanism of chemical sensitivity in multiple chemical sensitivity
    • Pall, M. L. NMDA sensitization and stimulation by peroxynitrite, nitric oxide and organic solvents as the mechanism of chemical sensitivity in multiple chemical sensitivity. FASEB J. 2002, 16, 1407-1417.
    • (2002) FASEB J. , vol.16 , pp. 1407-1417
    • Pall, M.L.1
  • 9
    • 34547852271 scopus 로고    scopus 로고
    • Nitric oxide synthase partial uncoupling as a key switching mechanism for the NO/ONOO-cycle
    • Pall, M. L. Nitric oxide synthase partial uncoupling as a key switching mechanism for the NO/ONOO-cycle. Med. Hypotheses 2007, 69, 821-825.
    • (2007) Med. Hypotheses , vol.69 , pp. 821-825
    • Pall, M.L.1
  • 10
    • 84860533793 scopus 로고    scopus 로고
    • 2+ signaling and TRP cation channel activation in nervous system
    • 2+ signaling and TRP cation channel activation in nervous system. J. Recept. Signal. Transduct. Res. 2012, 32, 134-141.
    • (2012) J. Recept. Signal. Transduct. Res. , vol.32 , pp. 134-141
    • Naziroǧlu, M.1
  • 11
    • 0037448784 scopus 로고    scopus 로고
    • Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction
    • Pacher, P.; Liaudet, L.; Bai, P.; Mabley, J. G.; Kaminski, P. M.; Virág, L.; Deb, A.; Szabó, E.; Ungvári, Z.; Wolin, M. S.; et al. Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction. Circulation 2003, 107, 896-904.
    • (2003) Circulation , vol.107 , pp. 896-904
    • Pacher, P.1    Liaudet, L.2    Bai, P.3    Mabley, J.G.4    Kaminski, P.M.5    Virág, L.6    Deb, A.7    Szabó, E.8    Ungvári, Z.9    Wolin, M.S.10
  • 12
    • 0035800858 scopus 로고    scopus 로고
    • Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation
    • Okamoto, T.; Akaike, T.; Sawa, T.; Miyamoto, Y.; van der Vliet, A.; Maeda, H. Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation. J. Biol. Chem. 2001, 276, 29596-29602.
    • (2001) J. Biol. Chem. , vol.276 , pp. 29596-29602
    • Okamoto, T.1    Akaike, T.2    Sawa, T.3    Miyamoto, Y.4    van der Vliet, A.5    Maeda, H.6
  • 14
    • 77955175462 scopus 로고    scopus 로고
    • Oxidative posttranslational modifications mediate decreased SERCA activity and myocyte dysfunction in Galphaq-overexpressing mice
    • Lancel, S.; Qin, F.; Lennon, S. L.; Zhang, J.; Tong, X.; Mazzini, M. J.; Kang, Y. J.; Siwik, D. A.; Cohen, R. A.; Colucci, W. S. Oxidative posttranslational modifications mediate decreased SERCA activity and myocyte dysfunction in Galphaq-overexpressing mice. Circ. Res. 2010, 107, 228-232.
    • (2010) Circ. Res. , vol.107 , pp. 228-232
    • Lancel, S.1    Qin, F.2    Lennon, S.L.3    Zhang, J.4    Tong, X.5    Mazzini, M.J.6    Kang, Y.J.7    Siwik, D.A.8    Cohen, R.A.9    Colucci, W.S.10
  • 15
    • 0035110310 scopus 로고    scopus 로고
    • Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure
    • Mihm, M. J.; Coyle, C. M.; Schanbacher, B. L.; Weinstein, D. M.; Bauer, J. A. Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure. Cardiovasc. Res. 2001, 49, 798-807.
    • (2001) Cardiovasc. Res. , vol.49 , pp. 798-807
    • Mihm, M.J.1    Coyle, C.M.2    Schanbacher, B.L.3    Weinstein, D.M.4    Bauer, J.A.5
  • 16
    • 33947703077 scopus 로고    scopus 로고
    • A peroxynitrite decomposition catalyst: FeTPPS confers cardioprotection during reperfusion after cardioplegic arrest in a working isolated rat heart model
    • Lauzier, B.; Sicard, P.; Bouchot, O.; Delemasure, S.; Moreau, D.; Vergely, C.; Rochette, L. A peroxynitrite decomposition catalyst: FeTPPS confers cardioprotection during reperfusion after cardioplegic arrest in a working isolated rat heart model. Fundam. Clin. Pharmacol. 2007, 21, 173-180.
    • (2007) Fundam. Clin. Pharmacol. , vol.21 , pp. 173-180
    • Lauzier, B.1    Sicard, P.2    Bouchot, O.3    Delemasure, S.4    Moreau, D.5    Vergely, C.6    Rochette, L.7
  • 18
  • 19
    • 0033900011 scopus 로고    scopus 로고
    • Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure
    • Ferdinandy, P.; Danial, H.; Ambrus, I.; Rothery, R. A.; Schulz, R. Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure. Circ. Res. 2000, 87, 241-247.
    • (2000) Circ. Res. , vol.87 , pp. 241-247
    • Ferdinandy, P.1    Danial, H.2    Ambrus, I.3    Rothery, R.A.4    Schulz, R.5
  • 20
    • 38849193405 scopus 로고    scopus 로고
    • Targeting of phospholamban by peroxynitrite decreases beta-adrenergic stimulation in cardiomyocytes
    • Kohr, M. J.; Wang, H.; Wheeler, D. G.; Velayutham, M.; Zweier, J. L.; Ziolo, M. T. Targeting of phospholamban by peroxynitrite decreases beta-adrenergic stimulation in cardiomyocytes. Cardiovasc. Res. 2008, 77, 353-361.
    • (2008) Cardiovasc. Res. , vol.77 , pp. 353-361
    • Kohr, M.J.1    Wang, H.2    Wheeler, D.G.3    Velayutham, M.4    Zweier, J.L.5    Ziolo, M.T.6
  • 21
    • 77950576375 scopus 로고    scopus 로고
    • Endotoxin conditioning induces VCP/p97-mediated and inducible nitric-oxide synthase-dependent Tyr284 nitration in protein phosphatase 2A
    • Ohama, T.; Brautigan, D. L. Endotoxin conditioning induces VCP/p97-mediated and inducible nitric-oxide synthase-dependent Tyr284 nitration in protein phosphatase 2A. J. Biol. Chem. 2010, 285, 8711-8718.
    • (2010) J. Biol. Chem. , vol.285 , pp. 8711-8718
    • Ohama, T.1    Brautigan, D.L.2
  • 23
    • 77649273442 scopus 로고    scopus 로고
    • cAMP-independent activation of protein kinase A by the peroxynitrite generator SIN-1 elicits positive inotropic effects in cardiomyocytes
    • Kohr, M. J.; Traynham, C. J.; Roof, S. R.; Davis, J. P.; Ziolo, M. T. cAMP-independent activation of protein kinase A by the peroxynitrite generator SIN-1 elicits positive inotropic effects in cardiomyocytes. J. Mol. Cell. Cardiol. 2010, 48, 645-648.
    • (2010) J. Mol. Cell. Cardiol. , vol.48 , pp. 645-648
    • Kohr, M.J.1    Traynham, C.J.2    Roof, S.R.3    Davis, J.P.4    Ziolo, M.T.5
  • 25
    • 43849090222 scopus 로고    scopus 로고
    • Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit
    • Madej, E.; Folkes, L. K.; Wardman, P.; Czapski, G.; Goldstein, S. Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit. Free Radic. Biol. Med. 2008, 44, 2013-2018.
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 2013-2018
    • Madej, E.1    Folkes, L.K.2    Wardman, P.3    Czapski, G.4    Goldstein, S.5
  • 27
    • 27844580204 scopus 로고    scopus 로고
    • Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure
    • Daiber, A.; Oelze, M.; Coldewey, M.; Kaiser, K.; Huth, C.; Schildknecht, S.; Bachschmid, M.; Nazirisadeh, Y.; Ullrich, V.; Mülsch, A.; et al. Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure. Biochem. Biophys. Res. Commun. 2005, 338, 1865-1874.
    • (2005) Biochem. Biophys. Res. Commun. , vol.338 , pp. 1865-1874
    • Daiber, A.1    Oelze, M.2    Coldewey, M.3    Kaiser, K.4    Huth, C.5    Schildknecht, S.6    Bachschmid, M.7    Nazirisadeh, Y.8    Ullrich, V.9    Mülsch, A.10
  • 29
    • 0025819380 scopus 로고
    • Oxygen free radicals and congestive heart failure
    • Belch, J. J.; Bridges, A. B.; Scott, N.; Chopra, M. Oxygen free radicals and congestive heart failure. Br. Heart J. 1991, 65, 245-248.
    • (1991) Br. Heart J. , vol.65 , pp. 245-248
    • Belch, J.J.1    Bridges, A.B.2    Scott, N.3    Chopra, M.4
  • 30
    • 0032574631 scopus 로고    scopus 로고
    • Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: A potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure
    • Mallat, Z.; Philip, I.; Lebret, M.; Chatel, D.; Maclouf, J.; Tedgui, A. Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: A potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure. Circulation 1998, 97, 1536-1539.
    • (1998) Circulation , vol.97 , pp. 1536-1539
    • Mallat, Z.1    Philip, I.2    Lebret, M.3    Chatel, D.4    Maclouf, J.5    Tedgui, A.6
  • 33
    • 13444280324 scopus 로고    scopus 로고
    • Enhanced oxidative stress in coronary heart disease and chronic heart failure as indicated by an increased 8-epi-PGF(2alpha)
    • Wolfram, R.; Oguogho, A.; Palumbo, B.; Sinzinger, H. Enhanced oxidative stress in coronary heart disease and chronic heart failure as indicated by an increased 8-epi-PGF(2alpha). Eur. J. Heart Fail. 2005, 7, 167-172.
    • (2005) Eur. J. Heart Fail. , vol.7 , pp. 167-172
    • Wolfram, R.1    Oguogho, A.2    Palumbo, B.3    Sinzinger, H.4
  • 34
    • 23744439518 scopus 로고    scopus 로고
    • Antioxidant status and biomarkers of oxidative stress in dogs with congestive heart failure
    • Freeman, L. M.; Rush, J. E.; Milbury, P. E.; Blumberg, J. B. Antioxidant status and biomarkers of oxidative stress in dogs with congestive heart failure. J. Vet. Intern. Med. 2005, 19, 537-541.
    • (2005) J. Vet. Intern. Med. , vol.19 , pp. 537-541
    • Freeman, L.M.1    Rush, J.E.2    Milbury, P.E.3    Blumberg, J.B.4
  • 36
    • 0035680903 scopus 로고    scopus 로고
    • The oxidative stress hypothesis of congestive heart failure: Radical thoughts
    • Mak, S.; Newton, G. E. The oxidative stress hypothesis of congestive heart failure: Radical thoughts. Chest 2001, 120, 2035-2046.
    • (2001) Chest , vol.120 , pp. 2035-2046
    • Mak, S.1    Newton, G.E.2
  • 37
  • 38
    • 0033567224 scopus 로고    scopus 로고
    • Cell-permeable superoxide dismutase and glutathione peroxidase mimetics afford superior protection against doxorubicin-induced cardiotoxicity: The role of reactive oxygen and nitrogen intermediates
    • Konorev, E. A.; Kennedy, M. C.; Kalyanaraman, B. Cell-permeable superoxide dismutase and glutathione peroxidase mimetics afford superior protection against doxorubicin-induced cardiotoxicity: The role of reactive oxygen and nitrogen intermediates. Arch. Biochem. Biophys. 1999, 368, 421-428.
    • (1999) Arch. Biochem. Biophys. , vol.368 , pp. 421-428
    • Konorev, E.A.1    Kennedy, M.C.2    Kalyanaraman, B.3
  • 39
    • 84877047948 scopus 로고    scopus 로고
    • Mitochondria-specific nano-emulsified therapy for myocardial protection against Doxorubicin-induced cardiotoxicity
    • Faulk, A.; Weissig, V.; Elbayoumi, T. Mitochondria-specific nano-emulsified therapy for myocardial protection against Doxorubicin-induced cardiotoxicity. Methods Mol. Biol. 2013, 991, 99-112.
    • (2013) Methods Mol. Biol. , vol.991 , pp. 99-112
    • Faulk, A.1    Weissig, V.2    Elbayoumi, T.3
  • 43
    • 33845539687 scopus 로고    scopus 로고
    • Melatonin protects against oxidative damage and restores expression of GLUT4 gene in the hyperthyroid rat heart
    • Ghosh, G.; De, K.; Maity, S.; Bandyopadhyay, D.; Bhattacharya, S.; Reiter, R. J.; Bandyopadhyay, A. Melatonin protects against oxidative damage and restores expression of GLUT4 gene in the hyperthyroid rat heart. J. Pineal Res. 2007, 42, 71-82.
    • (2007) J. Pineal Res. , vol.42 , pp. 71-82
    • Ghosh, G.1    De, K.2    Maity, S.3    Bandyopadhyay, D.4    Bhattacharya, S.5    Reiter, R.J.6    Bandyopadhyay, A.7
  • 44
    • 84555188518 scopus 로고    scopus 로고
    • Mitochondrial proteome remodelling in pressure overload-induced heart failure: The role of mitochondrial oxidative stress
    • Dai, D. F.; Hsieh, E. J.; Liu, Y.; Chen, T.; Beyer, R. P.; Chin, M. T.; MacCoss, M. J.; Rabinovitch, P. S. Mitochondrial proteome remodelling in pressure overload-induced heart failure: The role of mitochondrial oxidative stress. Cardiovasc. Res. 2012, 93, 79-88.
    • (2012) Cardiovasc. Res. , vol.93 , pp. 79-88
    • Dai, D.F.1    Hsieh, E.J.2    Liu, Y.3    Chen, T.4    Beyer, R.P.5    Chin, M.T.6    McCoss, M.J.7    Rabinovitch, P.S.8
  • 45
    • 33646679144 scopus 로고    scopus 로고
    • Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice
    • Matsushima, S.; Ide, T.; Yamato, M.; Matsusaka, H.; Hattori, F.; Ikeuchi, M.; Kubota, T.; Sunagawa, K.; Hasegawa, Y.; Kurihara, T.; et al. Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation 2006, 113, 1779-1786.
    • (2006) Circulation , vol.113 , pp. 1779-1786
    • Matsushima, S.1    Ide, T.2    Yamato, M.3    Matsusaka, H.4    Hattori, F.5    Ikeuchi, M.6    Kubota, T.7    Sunagawa, K.8    Hasegawa, Y.9    Kurihara, T.10
  • 46
    • 0034648827 scopus 로고    scopus 로고
    • Peroxynitrite reductase activity of bacterial peroxiredoxins
    • Bryk, R.; Griffin, P.; Nathan, C. Peroxynitrite reductase activity of bacterial peroxiredoxins. Nature 2000, 407, 211-215.
    • (2000) Nature , vol.407 , pp. 211-215
    • Bryk, R.1    Griffin, P.2    Nathan, C.3
  • 48
    • 47749137764 scopus 로고    scopus 로고
    • Nitrosative stress leads to protein glutathiolation, increased S-nitrosation, and up-regulation of peroxiredoxins in the heart
    • Reinartz, M.; Ding, Z.; Flögel, U.; Gödecke, A.; Schrader, J. Nitrosative stress leads to protein glutathiolation, increased S-nitrosation, and up-regulation of peroxiredoxins in the heart. J. Biol. Chem. 2008, 283, 17440-17449.
    • (2008) J. Biol. Chem. , vol.283 , pp. 17440-17449
    • Reinartz, M.1    Ding, Z.2    Flögel, U.3    Gödecke, A.4    Schrader, J.5
  • 50
    • 52949153528 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial DNA damage in heart failure
    • Tsutsui, H.; Kinugawa, S.; Matsushima, S. Oxidative stress and mitochondrial DNA damage in heart failure. Circ. J. 2008, 72, A31-A37.
    • (2008) Circ. J. , vol.72
    • Tsutsui, H.1    Kinugawa, S.2    Matsushima, S.3
  • 54
    • 59449104627 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress and dysfunction in myocardial remodelling
    • Tsutsui, H.; Kinugawa, S.; Matsushima, S. Mitochondrial oxidative stress and dysfunction in myocardial remodelling. Cardiovasc. Res. 2009, 81, 449-456.
    • (2009) Cardiovasc. Res. , vol.81 , pp. 449-456
    • Tsutsui, H.1    Kinugawa, S.2    Matsushima, S.3
  • 55
    • 0028888378 scopus 로고
    • Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect
    • Siveski-Iliskovic, N.; Hill, M.; Chow, D. A.; Singal, P. K. Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect. Circulation 1995, 91, 10-15.
    • (1995) Circulation , vol.91 , pp. 10-15
    • Siveski-Iliskovic, N.1    Hill, M.2    Chow, D.A.3    Singal, P.K.4
  • 56
    • 84878019062 scopus 로고    scopus 로고
    • Total antioxidant capacity of diet and risk of heart failure: A population-based prospective cohort of women
    • Rautiainen, S.; Levitan, E. B.; Mittleman, M. A.; Wolk, A. Total antioxidant capacity of diet and risk of heart failure: A population-based prospective cohort of women. Am. J. Med. 2013, 126, 494-500.
    • (2013) Am. J. Med. , vol.126 , pp. 494-500
    • Rautiainen, S.1    Levitan, E.B.2    Mittleman, M.A.3    Wolk, A.4
  • 57
    • 0038506708 scopus 로고    scopus 로고
    • The possible role of oxidative stress in heart failure and the potential of antioxidant intervention
    • Korantzopoulos, P.; Galaris, D.; Papaioannides, D.; Siogas, K. The possible role of oxidative stress in heart failure and the potential of antioxidant intervention. Med. Sci. Monit. 2003, 9, RA120-RA125.
    • (2003) Med. Sci. Monit. , vol.9
    • Korantzopoulos, P.1    Galaris, D.2    Papaioannides, D.3    Siogas, K.4
  • 58
    • 19944408195 scopus 로고    scopus 로고
    • Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure
    • (in Spanish)
    • Castro, P.; Pérez, O.; Greig, D.; Díaz-Araya, G.; Moraga, F.; Chiong, M.; Troncoso, R.; Padilla, I.; Vukasovic, J. L.; Corbalán, R.; et al. Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure. Rev. Esp. Cardiol. 2004, 57, 1053-1058 (in Spanish).
    • (2004) Rev. Esp. Cardiol. , vol.57 , pp. 1053-1058
    • Castro, P.1    Pérez, O.2    Greig, D.3    Díaz-Araya, G.4    Moraga, F.5    Chiong, M.6    Troncoso, R.7    Padilla, I.8    Vukasovic, J.L.9    Corbalán, R.10
  • 60
    • 84863780150 scopus 로고    scopus 로고
    • Luteolin ameliorates cardiac failure in type I diabetic cardiomyopathy
    • Wang, G.; Li, W.; Lu, X.; Bao, P.; Zhao, X. Luteolin ameliorates cardiac failure in type I diabetic cardiomyopathy. J. Diabetes Complicat. 2012, 26, 259-265.
    • (2012) J. Diabetes Complicat. , vol.26 , pp. 259-265
    • Wang, G.1    Li, W.2    Lu, X.3    Bao, P.4    Zhao, X.5
  • 62
    • 84871721470 scopus 로고    scopus 로고
    • EGCG inhibits CTGF expression via blocking NF-κB activation in cardiac fibroblast
    • Cai, Y.; Yu, S. S.; Chen, T. T.; Gao, S.; Geng, B.; Yu, Y.; Ye, J. T.; Liu, P. Q. EGCG inhibits CTGF expression via blocking NF-κB activation in cardiac fibroblast. Phytomedicine 2013, 20, 106-113.
    • (2013) Phytomedicine , vol.20 , pp. 106-113
    • Cai, Y.1    Yu, S.S.2    Chen, T.T.3    Gao, S.4    Geng, B.5    Yu, Y.6    Ye, J.T.7    Liu, P.Q.8
  • 64
    • 0035811062 scopus 로고    scopus 로고
    • Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes
    • Purcell, N. H.; Tang, G.; Yu, C.; Mercurio, F.; DiDonato, J. A.; Lin, A. Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proc. Natl. Acad. Sci. USA 2001, 98, 6668-6673.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6668-6673
    • Purcell, N.H.1    Tang, G.2    Yu, C.3    Mercurio, F.4    DiDonato, J.A.5    Lin, A.6
  • 66
    • 42749093343 scopus 로고    scopus 로고
    • Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-kappaB pathways and mitochondrial protective mechanisms
    • Xu, Z.; Lin, S.; Wu, W.; Tan, H.; Wang, Z.; Cheng, C.; Lu, L.; Zhang, X. Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-kappaB pathways and mitochondrial protective mechanisms. Toxicology 2008, 247, 133-138.
    • (2008) Toxicology , vol.247 , pp. 133-138
    • Xu, Z.1    Lin, S.2    Wu, W.3    Tan, H.4    Wang, Z.5    Cheng, C.6    Lu, L.7    Zhang, X.8
  • 67
    • 84878339842 scopus 로고    scopus 로고
    • Cardioprotective effects of the YiQiFuMai injection and isolated compounds on attenuating chronic heart failure via NF-κB inactivation and cytokine suppression
    • Xing, L.; Jiang, M.; Dong, L.; Gao, J.; Hou, Y.; Bai, G.; Luo, G. Cardioprotective effects of the YiQiFuMai injection and isolated compounds on attenuating chronic heart failure via NF-κB inactivation and cytokine suppression. J. Ethnopharmacol. 2013, 148, 239-245.
    • (2013) J. Ethnopharmacol. , vol.148 , pp. 239-245
    • Xing, L.1    Jiang, M.2    Dong, L.3    Gao, J.4    Hou, Y.5    Bai, G.6    Luo, G.7
  • 69
    • 84871910829 scopus 로고    scopus 로고
    • A-kinase-anchoring protein-Lbc anchors IκB kinase β to support interleukin-6-mediated cardiomyocyte hypertrophy
    • Del Vescovo, C. D.; Cotecchia, S.; Diviani, D. A-kinase-anchoring protein-Lbc anchors IκB kinase β to support interleukin-6-mediated cardiomyocyte hypertrophy. Mol. Cell. Biol. 2013, 33, 14-27.
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 14-27
    • Del Vescovo, C.D.1    Cotecchia, S.2    Diviani, D.3
  • 70
    • 78650443223 scopus 로고    scopus 로고
    • Cardiomyocyte NF-κB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure
    • Hamid, T.; Guo, S. Z.; Kingery, J. R.; Xiang, X.; Dawn, B.; Prabhu, S. D. Cardiomyocyte NF-κB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure. Cardiovasc. Res. 2011, 89, 129-138.
    • (2011) Cardiovasc. Res. , vol.89 , pp. 129-138
    • Hamid, T.1    Guo, S.Z.2    Kingery, J.R.3    Xiang, X.4    Dawn, B.5    Prabhu, S.D.6
  • 72
    • 0026735208 scopus 로고
    • Negative inotropic effects of cytokines on the heart mediated by nitric oxide
    • Finkel, M. S.; Oddis, C. V.; Jacob, T. D.; Watkins, S. C.; Hattler, B. G.; Simmons, R. L. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science 1992, 257, 387-389.
    • (1992) Science , vol.257 , pp. 387-389
    • Finkel, M.S.1    Oddis, C.V.2    Jacob, T.D.3    Watkins, S.C.4    Hattler, B.G.5    Simmons, R.L.6
  • 73
    • 0031159090 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of tumor necrosis factor-alpha causes lethal myocarditis in transgenic mice
    • Kubota, T.; McTiernan, C. F.; Frye, C. S.; Demetris, A. J.; Feldman, A. M. Cardiac-specific overexpression of tumor necrosis factor-alpha causes lethal myocarditis in transgenic mice. J. Card. Fail. 1997, 3, 117-124.
    • (1997) J. Card. Fail. , vol.3 , pp. 117-124
    • Kubota, T.1    McTiernan, C.F.2    Frye, C.S.3    Demetris, A.J.4    Feldman, A.M.5
  • 75
    • 83455168966 scopus 로고    scopus 로고
    • Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias
    • Yajima, T.; Murofushi, Y.; Zhou, H.; Park, S.; Housman, J.; Zhong, Z. H.; Nakamura, M.; Machida, M.; Hwang, K. K.; Gu, Y.; et al. Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias. Circulation 2011, 124, 2690-2701.
    • (2011) Circulation , vol.124 , pp. 2690-2701
    • Yajima, T.1    Murofushi, Y.2    Zhou, H.3    Park, S.4    Housman, J.5    Zhong, Z.H.6    Nakamura, M.7    Machida, M.8    Hwang, K.K.9    Gu, Y.10
  • 76
    • 0031005027 scopus 로고    scopus 로고
    • Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB
    • Ohmori, Y.; Schreiber, R. D.; Hamilton, T. A. Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB. J. Biol. Chem. 1997, 272, 14899-14907.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14899-14907
    • Ohmori, Y.1    Schreiber, R.D.2    Hamilton, T.A.3
  • 77
    • 0026542187 scopus 로고
    • Induction and potential biological relevance of a Ca2+-independent nitric oxide synthase in the myocardium
    • Schulz, R.; Nava, E.; Moncada, S. Induction and potential biological relevance of a Ca2+-independent nitric oxide synthase in the myocardium. Br. J. Pharmacol. 1992, 105, 575-580.
    • (1992) Br. J. Pharmacol. , vol.105 , pp. 575-580
    • Schulz, R.1    Nava, E.2    Moncada, S.3
  • 79
    • 84872943892 scopus 로고    scopus 로고
    • Attenuated expression of gelsolin in association with induction of aquaporin-1 and nitric oxide synthase in dysfunctional hearts of aging mice exposed to endotoxin
    • Madonna, R.; Jiang, J.; Geng, Y. J. Attenuated expression of gelsolin in association with induction of aquaporin-1 and nitric oxide synthase in dysfunctional hearts of aging mice exposed to endotoxin. Int. J. Immunopathol. Pharmacol. 2012, 25, 911-922.
    • (2012) Int. J. Immunopathol. Pharmacol. , vol.25 , pp. 911-922
    • Madonna, R.1    Jiang, J.2    Geng, Y.J.3
  • 81
    • 83055178987 scopus 로고    scopus 로고
    • The relative efficacy of aminoguanidine and pentoxifylline in modulating endotoxin-induced cardiac stress
    • Motawi, T. K.; Darwish, H. A.; Abd El Tawab, A. M. The relative efficacy of aminoguanidine and pentoxifylline in modulating endotoxin-induced cardiac stress. Cell Biochem. Funct. 2011, 29, 694-702.
    • (2011) Cell Biochem. Funct. , vol.29 , pp. 694-702
    • Motawi, T.K.1    Darwish, H.A.2    Abd El Tawab, A.M.3
  • 83
    • 0038498077 scopus 로고    scopus 로고
    • Myoglobin protects the heart from inducible nitric-oxide synthase (iNOS)-mediated nitrosative stress
    • Gödecke, A.; Molojavyi, A.; Heger, J.; Flögel, U.; Ding, Z.; Jacoby, C.; Schrader, J. Myoglobin protects the heart from inducible nitric-oxide synthase (iNOS)-mediated nitrosative stress. J. Biol. Chem. 2003, 278, 21761-21766.
    • (2003) J. Biol. Chem. , vol.278 , pp. 21761-21766
    • Gödecke, A.1    Molojavyi, A.2    Heger, J.3    Flögel, U.4    Ding, Z.5    Jacoby, C.6    Schrader, J.7
  • 85
    • 0032192130 scopus 로고    scopus 로고
    • Expression, activity and functional significance of inducible nitric oxide synthase in the failing human heart
    • Drexler, H.; Kästner, S.; Strobel, A.; Studer, R.; Brodde, O. E.; Hasenfuss, G. Expression, activity and functional significance of inducible nitric oxide synthase in the failing human heart. J. Am. Coll. Cardiol. 1998, 32, 955-963.
    • (1998) J. Am. Coll. Cardiol. , vol.32 , pp. 955-963
    • Drexler, H.1    Kästner, S.2    Strobel, A.3    Studer, R.4    Brodde, O.E.5    Hasenfuss, G.6
  • 87
    • 77954525347 scopus 로고    scopus 로고
    • Ablation of iNOS delays cardiac contractile dysfunction in chronic hypertension
    • Dias, F. A. L.; Urboniene, D.; Wolska, B. M. Ablation of iNOS delays cardiac contractile dysfunction in chronic hypertension. Front. Biosci. 2010, 2, 312-324.
    • (2010) Front. Biosci. , vol.2 , pp. 312-324
    • Dias, F.A.L.1    Urboniene, D.2    Wolska, B.M.3
  • 90
    • 0036300359 scopus 로고    scopus 로고
    • Increased nitric oxide in proportion to the severity of heart failure in patients with dilated cardiomyopathy: Close correlation of tumor necrosis factor-alpha with systemic and local production of nitric oxide
    • Sugamori, T.; Ishibashi, Y.; Shimada, T.; Takahashi, N.; Sakane, T.; Ohata, S.; Kunizawa, Y.; Inoue, S.; Nakamura, K.; Ohta, Y.; et al. Increased nitric oxide in proportion to the severity of heart failure in patients with dilated cardiomyopathy: Close correlation of tumor necrosis factor-alpha with systemic and local production of nitric oxide. Circ. J. 2002, 66, 627-632.
    • (2002) Circ. J. , vol.66 , pp. 627-632
    • Sugamori, T.1    Ishibashi, Y.2    Shimada, T.3    Takahashi, N.4    Sakane, T.5    Ohata, S.6    Kunizawa, Y.7    Inoue, S.8    Nakamura, K.9    Ohta, Y.10
  • 91
    • 0032557388 scopus 로고    scopus 로고
    • Increased endogenous nitric oxide synthase inhibitor in patients with congestive heart failure
    • Usui, M.; Matsuoka, H.; Miyazaki, H.; Ueda, S.; Okuda, S.; Imaizumi, T. Increased endogenous nitric oxide synthase inhibitor in patients with congestive heart failure. Life Sci. 1998, 62, 2425-2430.
    • (1998) Life Sci. , vol.62 , pp. 2425-2430
    • Usui, M.1    Matsuoka, H.2    Miyazaki, H.3    Ueda, S.4    Okuda, S.5    Imaizumi, T.6
  • 92
    • 0038143308 scopus 로고    scopus 로고
    • Serum nitrate and nitrite in dogs with spontaneous cardiac disease
    • De Laforcade, A. M.; Freeman, L. M.; Rush, J. E. Serum nitrate and nitrite in dogs with spontaneous cardiac disease. J. Vet. Intern. Med. 2003, 17, 315-318.
    • (2003) J. Vet. Intern. Med. , vol.17 , pp. 315-318
    • De Laforcade, A.M.1    Freeman, L.M.2    Rush, J.E.3
  • 93
    • 0035887137 scopus 로고    scopus 로고
    • Plasma nitric oxide level in heart failure secondary to left ventricular diastolic dysfunction
    • Yu, C. M.; Fung, P. C.; Chan, G.; Lai, K. W.; Wang, Q.; Lau, C. P. Plasma nitric oxide level in heart failure secondary to left ventricular diastolic dysfunction. Am. J. Cardiol. 2001, 88, 867-870.
    • (2001) Am. J. Cardiol. , vol.88 , pp. 867-870
    • Yu, C.M.1    Fung, P.C.2    Chan, G.3    Lai, K.W.4    Wang, Q.5    Lau, C.P.6
  • 95
    • 0032579551 scopus 로고    scopus 로고
    • The failing human heart does not release nitrogen oxides
    • Kaye, D. M.; Chin-Dusting, J.; Esler, M. D.; Jennings, G. L. The failing human heart does not release nitrogen oxides. Life Sci. 1998, 62, 883-887.
    • (1998) Life Sci. , vol.62 , pp. 883-887
    • Kaye, D.M.1    Chin-Dusting, J.2    Esler, M.D.3    Jennings, G.L.4
  • 96
    • 0027447237 scopus 로고
    • Measurement of nitric oxide in biological models
    • Archer, S. Measurement of nitric oxide in biological models. FASEB J. 1993, 7, 349-360.
    • (1993) FASEB J. , vol.7 , pp. 349-360
    • Archer, S.1
  • 97
    • 0028364425 scopus 로고
    • Nitric oxide assay using hemoglobin method
    • Murphy, M. E.; Noack, E. Nitric oxide assay using hemoglobin method. Methods Enzymol. 1994, 233, 240-250.
    • (1994) Methods Enzymol. , vol.233 , pp. 240-250
    • Murphy, M.E.1    Noack, E.2
  • 98
    • 17044366543 scopus 로고    scopus 로고
    • Erythrocyte membrane fluidity and haemoglobin haemoporphyrin conformation: Features revealed in patients with heart failure
    • Rodnenkov, O. V.; Luneva, O. G.; Ulyanova, N. A.; Maksimov, G. V.; Rubin, A. B.; Orlov, S. N.; Chazov, E. I. Erythrocyte membrane fluidity and haemoglobin haemoporphyrin conformation: Features revealed in patients with heart failure. Pathophysiology 2005, 11, 209-213.
    • (2005) Pathophysiology , vol.11 , pp. 209-213
    • Rodnenkov, O.V.1    Luneva, O.G.2    Ulyanova, N.A.3    Maksimov, G.V.4    Rubin, A.B.5    Orlov, S.N.6    Chazov, E.I.7
  • 99
    • 0031934968 scopus 로고    scopus 로고
    • Decreased basal production of nitric oxide in patients with heart disease
    • Sumino, H.; Sato, K.; Sakamaki, T.; Masuda, H.; Nakamura, T.; Kanda, T.; Nagai, R. Decreased basal production of nitric oxide in patients with heart disease. Chest 1998, 113, 317-322.
    • (1998) Chest , vol.113 , pp. 317-322
    • Sumino, H.1    Sato, K.2    Sakamaki, T.3    Masuda, H.4    Nakamura, T.5    Kanda, T.6    Nagai, R.7
  • 100
    • 0033609027 scopus 로고    scopus 로고
    • Decreased activity of the L-arginine-nitric oxide metabolic pathway in patients with congestive heart failure
    • Katz, S. D.; Khan, T.; Zeballos, G. A.; Mathew, L.; Potharlanka, P.; Knecht, M.; Whelan, J. Decreased activity of the L-arginine-nitric oxide metabolic pathway in patients with congestive heart failure. Circulation 1999, 99, 2113-2117.
    • (1999) Circulation , vol.99 , pp. 2113-2117
    • Katz, S.D.1    Khan, T.2    Zeballos, G.A.3    Mathew, L.4    Potharlanka, P.5    Knecht, M.6    Whelan, J.7
  • 101
    • 67650239426 scopus 로고    scopus 로고
    • The role of nitric oxide in myocardial repair and remodeling
    • Otani, H. The role of nitric oxide in myocardial repair and remodeling. Antioxid. Redox Signal. 2009, 11, 1913-1928.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 1913-1928
    • Otani, H.1
  • 103
    • 77956283047 scopus 로고    scopus 로고
    • cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action
    • Francis, S. H.; Busch, J. L.; Corbin, J. D.; Sibley, D. cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action. Pharmacol. Rev. 2010, 62, 525-563.
    • (2010) Pharmacol. Rev. , vol.62 , pp. 525-563
    • Francis, S.H.1    Busch, J.L.2    Corbin, J.D.3    Sibley, D.4
  • 104
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • Pacher, P.; Beckman, J. S.; Liaudet, L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 2007, 87, 315-424.
    • (2007) Physiol. Rev. , vol.87 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 105
    • 0029037495 scopus 로고
    • The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
    • Pryor, W. A.; Squadrito, G. L. The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide. Am. J. Physiol. 1995, 268, L699-L722.
    • (1995) Am. J. Physiol. , vol.268
    • Pryor, W.A.1    Squadrito, G.L.2
  • 110
    • 84880544313 scopus 로고    scopus 로고
    • Protein kinase G Iα inhibits pressure overload-induced cardiac remodeling and is required for the cardioprotective effect of sildenafil in vivo
    • Blanton, R. M.; Takimoto, E.; Lane, A. M.; Aronovitz, M.; Piotrowski, R.; Karas, R. H.; Kass, D. A.; Mendelsohn, M. E. Protein kinase G Iα inhibits pressure overload-induced cardiac remodeling and is required for the cardioprotective effect of sildenafil in vivo. J. Am. Heart Assoc. 2012, 1, e003731.
    • (2012) J. Am. Heart Assoc. , vol.1
    • Blanton, R.M.1    Takimoto, E.2    Lane, A.M.3    Aronovitz, M.4    Piotrowski, R.5    Karas, R.H.6    Kass, D.A.7    Mendelsohn, M.E.8
  • 111
    • 84868219699 scopus 로고    scopus 로고
    • Selective PDE5A inhibition with sildenafil rescues left ventricular dysfunction, inflammatory immune response and cardiac remodeling in angiotensin II-induced heart failure in vivo
    • Westermann, D.; Becher, P. M.; Lindner, D.; Savvatis, K.; Xia, Y.; Fröhlich, M.; Hoffmann, S.; Schultheiss, H. P.; Tschöpe, C. Selective PDE5A inhibition with sildenafil rescues left ventricular dysfunction, inflammatory immune response and cardiac remodeling in angiotensin II-induced heart failure in vivo. Basic Res. Cardiol. 2012, 107, 308.
    • (2012) Basic Res. Cardiol. , vol.107 , pp. 308
    • Westermann, D.1    Becher, P.M.2    Lindner, D.3    Savvatis, K.4    Xia, Y.5    Fröhlich, M.6    Hoffmann, S.7    Schultheiss, H.P.8    Tschöpe, C.9
  • 115
    • 35348919542 scopus 로고    scopus 로고
    • Regulation of cGMP-dependent protein kinase-mediated vasodilation by hypoxia-induced reactive species in ovine fetal pulmonary veins
    • Negash, S.; Gao, Y.; Zhou, W.; Liu, J.; Chinta, S.; Raj, J. U. Regulation of cGMP-dependent protein kinase-mediated vasodilation by hypoxia-induced reactive species in ovine fetal pulmonary veins. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 293, L1012-L1020.
    • (2007) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.293
    • Negash, S.1    Gao, Y.2    Zhou, W.3    Liu, J.4    Chinta, S.5    Raj, J.U.6
  • 117
    • 77951293073 scopus 로고    scopus 로고
    • A novel insight into the mechanism of pulmonary hypertension involving caveolin-1 deficiency and endothelial nitric oxide synthase activation
    • Zhao, Y. Y.; Malik, A. B. A novel insight into the mechanism of pulmonary hypertension involving caveolin-1 deficiency and endothelial nitric oxide synthase activation. Trends Cardiovasc. Med. 2009, 19, 238-242.
    • (2009) Trends Cardiovasc. Med. , vol.19 , pp. 238-242
    • Zhao, Y.Y.1    Malik, A.B.2
  • 118
    • 84877095847 scopus 로고    scopus 로고
    • Volume overload induces differential spatiotemporal regulation of myocardial soluble guanylyl cyclase in eccentric hypertrophy and heart failure
    • Liu, Y.; Dillon, A. R.; Tillson, M.; Makarewich, C.; Nguyen, V.; Dell'italia, L.; Sabri, A. K.; Rizzo, V.; Tsai, E. J. Volume overload induces differential spatiotemporal regulation of myocardial soluble guanylyl cyclase in eccentric hypertrophy and heart failure. J. Mol. Cell. Cardiol. 2013, 60C, 72-83.
    • (2013) J. Mol. Cell. Cardiol. , vol.60 C , pp. 72-83
    • Liu, Y.1    Dillon, A.R.2    Tillson, M.3    Makarewich, C.4    Nguyen, V.5    Dell'italia, L.6    Sabri, A.K.7    Rizzo, V.8    Tsai, E.J.9
  • 120
    • 27244442100 scopus 로고    scopus 로고
    • Cyclic GMP production by ANP, BNP, and NO during worsening and improvement of chronic heart failure
    • Takahashi, M.; Takeda, S.; Kurokawa, S.; Kubo, T.; Fukuda, N.; Izumi, T. Cyclic GMP production by ANP, BNP, and NO during worsening and improvement of chronic heart failure. Jpn. Heart J. 2003, 44, 713-724.
    • (2003) Jpn. Heart J. , vol.44 , pp. 713-724
    • Takahashi, M.1    Takeda, S.2    Kurokawa, S.3    Kubo, T.4    Fukuda, N.5    Izumi, T.6
  • 121
    • 52049121992 scopus 로고    scopus 로고
    • Natriuretic peptides in vascular physiology and pathology
    • Woodard, G. E.; Rosado, J. A. Natriuretic peptides in vascular physiology and pathology. Int. Rev. Cell. Mol. Biol. 2008, 268, 59-93.
    • (2008) Int. Rev. Cell. Mol. Biol. , vol.268 , pp. 59-93
    • Woodard, G.E.1    Rosado, J.A.2
  • 122
    • 34347227801 scopus 로고    scopus 로고
    • Differential regulation of membrane guanylyl cyclases in congestive heart failure: Natriuretic peptide receptor (NPR)-B, not NPR-A, is the predominant natriuretic peptide receptor in the failing heart
    • Dickey, D. M.; Flora, D. R.; Bryan, P. M.; Xu, X.; Chen, Y.; Potter, L. R. Differential regulation of membrane guanylyl cyclases in congestive heart failure: Natriuretic peptide receptor (NPR)-B, not NPR-A, is the predominant natriuretic peptide receptor in the failing heart. Endocrinology 2007, 148, 3518-3522.
    • (2007) Endocrinology , vol.148 , pp. 3518-3522
    • Dickey, D.M.1    Flora, D.R.2    Bryan, P.M.3    Xu, X.4    Chen, Y.5    Potter, L.R.6
  • 123
    • 0032698316 scopus 로고    scopus 로고
    • Cytokine-mediated apoptosis in cardiac myocytes: The role of inducible nitric oxide synthase induction and peroxynitrite generation
    • Arstall, M. A.; Sawyer, D. B.; Fukazawa, R.; Kelly, R. A. Cytokine-mediated apoptosis in cardiac myocytes: The role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ. Res. 1999, 85, 829-840.
    • (1999) Circ. Res. , vol.85 , pp. 829-840
    • Arstall, M.A.1    Sawyer, D.B.2    Fukazawa, R.3    Kelly, R.A.4
  • 124
    • 84873413349 scopus 로고    scopus 로고
    • Mitochondria as a therapeutic target in heart failure
    • Bayeva, M.; Gheorghiade, M.; Ardehali, H. Mitochondria as a therapeutic target in heart failure. J. Am. Coll. Cardiol. 2013, 61, 599-610.
    • (2013) J. Am. Coll. Cardiol. , vol.61 , pp. 599-610
    • Bayeva, M.1    Gheorghiade, M.2    Ardehali, H.3
  • 126
    • 0036278865 scopus 로고    scopus 로고
    • Electron transport chain defects in heart failure
    • Casademont, J.; Miró, O. Electron transport chain defects in heart failure. Heart Fail. Rev. 2002, 7, 131-139.
    • (2002) Heart Fail. Rev. , vol.7 , pp. 131-139
    • Casademont, J.1    Miró, O.2
  • 127
    • 84872676487 scopus 로고    scopus 로고
    • Mitochondria in cardiac hypertrophy and heart failure
    • Rosca, M. G.; Tandler, B.; Hoppel, C. L. Mitochondria in cardiac hypertrophy and heart failure. J. Mol. Cell. Cardiol. 2013, 55, 31-41.
    • (2013) J. Mol. Cell. Cardiol. , vol.55 , pp. 31-41
    • Rosca, M.G.1    Tandler, B.2    Hoppel, C.L.3
  • 128
    • 77956586695 scopus 로고    scopus 로고
    • Mitochondria in heart failure
    • Rosca, M. G.; Hoppel, C. L. Mitochondria in heart failure. Cardiovasc. Res. 2010, 88, 40-50.
    • (2010) Cardiovasc. Res. , vol.88 , pp. 40-50
    • Rosca, M.G.1    Hoppel, C.L.2
  • 131
    • 77649232263 scopus 로고    scopus 로고
    • Energetic myocardial metabolism and oxidative stress: Let's make them our friends in the fight against heart failure
    • Scolletta, S.; Biagioli, B. Energetic myocardial metabolism and oxidative stress: Let's make them our friends in the fight against heart failure. Biomed. Pharmacother. 2010, 64, 203-207.
    • (2010) Biomed. Pharmacother. , vol.64 , pp. 203-207
    • Scolletta, S.1    Biagioli, B.2
  • 132
    • 79957937929 scopus 로고    scopus 로고
    • Targeting fatty acid and carbohydrate oxidation-A novel therapeutic intervention in the ischemic and failing heart
    • Jaswal, J. S.; Keung, W.; Wang, W.; Ussher, J. R.; Lopaschuk, G. D. Targeting fatty acid and carbohydrate oxidation-A novel therapeutic intervention in the ischemic and failing heart. Biochim. Biophys. Acta 2011 1813, 1333-1350.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1333-1350
    • Jaswal, J.S.1    Keung, W.2    Wang, W.3    Ussher, J.R.4    Lopaschuk, G.D.5
  • 134
    • 84856109625 scopus 로고    scopus 로고
    • Mitochondrial fusion is essential for organelle function and cardiac homeostasis
    • Chen, Y.; Liu, Y.; Dorn, G. W., 2nd. Mitochondrial fusion is essential for organelle function and cardiac homeostasis. Circ. Res. 2011, 109, 1327-1331.
    • (2011) Circ. Res. , vol.109 , pp. 1327-1331
    • Chen, Y.1    Liu, Y.2    Dorn II, G.W.3
  • 135
    • 79959886319 scopus 로고    scopus 로고
    • Systolic dysfunction in cardiac-specific ligand-inducible MerCreMer transgenic mice
    • Hal, M. E.; Smith, G.; Hall, J. E.; Stec, D. E. Systolic dysfunction in cardiac-specific ligand-inducible MerCreMer transgenic mice. Am. J. Physiol. Heart Circ. Physiol. 2011, 301, H253-H260.
    • (2011) Am. J. Physiol. Heart Circ. Physiol. , vol.301
    • Hal, M.E.1    Smith, G.2    Hall, J.E.3    Stec, D.E.4
  • 137
    • 10644296223 scopus 로고    scopus 로고
    • Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: A review
    • Ferrari, R.; Merli, E.; Cicchitelli, G.; Mele, D.; Fucili, A.; Ceconi, C. Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: A review. Ann. N. Y. Acad. Sci. 2004, 1033, 79-91.
    • (2004) Ann. N.Y. Acad. Sci. , vol.1033 , pp. 79-91
    • Ferrari, R.1    Merli, E.2    Cicchitelli, G.3    Mele, D.4    Fucili, A.5    Ceconi, C.6
  • 139
    • 84858077778 scopus 로고    scopus 로고
    • Carnitine derivatives: Clinical usefulness
    • Malaguarnera, M. Carnitine derivatives: Clinical usefulness. Curr. Opin. Gastroenterol. 2012, 28, 166-176.
    • (2012) Curr. Opin. Gastroenterol. , vol.28 , pp. 166-176
    • Malaguarnera, M.1
  • 140
    • 84873399755 scopus 로고    scopus 로고
    • Effect of coenzyme Q10 supplementation on heart failure: A meta-analysis
    • Fotino, A. D.; Thompson-Paul, A. M.; Bazzano, L. A. Effect of coenzyme Q10 supplementation on heart failure: A meta-analysis. Am. J. Clin. Nutr. 2013, 97, 268-275.
    • (2013) Am. J. Clin. Nutr. , vol.97 , pp. 268-275
    • Fotino, A.D.1    Thompson-Paul, A.M.2    Bazzano, L.A.3
  • 141
    • 84873369195 scopus 로고    scopus 로고
    • The benefit of coenzyme Q10 supplements in the management of chronic heart failure: A long tale of promise in the continued absence of clear evidence
    • Stocker, R.; Macdonald, P. The benefit of coenzyme Q10 supplements in the management of chronic heart failure: A long tale of promise in the continued absence of clear evidence. Am. J. Clin. Nutr. 2013, 97, 233-234.
    • (2013) Am. J. Clin. Nutr. , vol.97 , pp. 233-234
    • Stocker, R.1    Macdonald, P.2
  • 144
    • 47649122637 scopus 로고    scopus 로고
    • Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: Efficacy of recoupling nitric oxide synthase as a therapeutic strategy
    • Moens, A. L.; Takimoto, E.; Tocchetti, C. G.; Chakir, K.; Bedja, D.; Cormaci, G.; Ketner, E. A.; Majmudar, M.; Gabrielson, K.; Halushka, M. K.; et al. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: Efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation 2008, 117, 2626-2636.
    • (2008) Circulation , vol.117 , pp. 2626-2636
    • Moens, A.L.1    Takimoto, E.2    Tocchetti, C.G.3    Chakir, K.4    Bedja, D.5    Cormaci, G.6    Ketner, E.A.7    Majmudar, M.8    Gabrielson, K.9    Halushka, M.K.10
  • 145
    • 79958814583 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase inhibition improves diastolic function and reduces oxidative stress in ovariectomized mRen2. Lewis rats
    • Jessup, J. A.; Zhang, L.; Chen, A. F.; Presley, T. D.; Kim-Shapiro, D. B.; Chappell, M. C.; Wang, H.; Groban, L. Neuronal nitric oxide synthase inhibition improves diastolic function and reduces oxidative stress in ovariectomized mRen2. Lewis rats. Menopause 2011, 18, 698-708.
    • (2011) Menopause , vol.18 , pp. 698-708
    • Jessup, J.A.1    Zhang, L.2    Chen, A.F.3    Presley, T.D.4    Kim-Shapiro, D.B.5    Chappell, M.C.6    Wang, H.7    Groban, L.8
  • 147
    • 79960778588 scopus 로고    scopus 로고
    • Is NOS uncoupling the missing link between atrial fibrillation and chronic non-ischaemic cardiomyopathy?
    • Crijns, H. J.; Schotten, U.; Moens, A. L. Is NOS uncoupling the missing link between atrial fibrillation and chronic non-ischaemic cardiomyopathy? Cardiovasc. Res. 2011, 91, 556.
    • (2011) Cardiovasc. Res. , vol.91 , pp. 556
    • Crijns, H.J.1    Schotten, U.2    Moens, A.L.3
  • 148
    • 79960773257 scopus 로고    scopus 로고
    • Is NOS uncoupling the missing link between atrial fibrillation and chronic non-ischaemic cardiomyopathy? Author reply
    • Nishijima, Y.; Sridhar, A.; Zweier, J. L.; Cardounel, A. J.; Carnes, C. A. Is NOS uncoupling the missing link between atrial fibrillation and chronic non-ischaemic cardiomyopathy? Author reply. Cardiovasc. Res. 2011, 91, 557-558.
    • (2011) Cardiovasc. Res. , vol.91 , pp. 557-558
    • Nishijima, Y.1    Sridhar, A.2    Zweier, J.L.3    Cardounel, A.J.4    Carnes, C.A.5
  • 149
    • 84871887089 scopus 로고    scopus 로고
    • Recoupling of cardiac nitric oxide synthases: Tetrahydrobiopterin synthesis and recycling
    • Alkaitis, M. S.; Crabtree, M. J. Recoupling of cardiac nitric oxide synthases: Tetrahydrobiopterin synthesis and recycling. Curr. Heart Fail. Rep. 2012, 9, 200-210.
    • (2012) Curr. Heart Fail. Rep. , vol.9 , pp. 200-210
    • Alkaitis, M.S.1    Crabtree, M.J.2
  • 150
    • 84879417817 scopus 로고    scopus 로고
    • Nitric oxide bioavailability and adiponectin production in chronic systolic heart failure: Relation to severity of cardiac dysfunction
    • Tang, W. H.; Shrestha, K.; Tong, W.; Wang, Z.; Troughton, R. W.; Borowski, A. G.; Klein, A. L.; Hazen, S. L. Nitric oxide bioavailability and adiponectin production in chronic systolic heart failure: Relation to severity of cardiac dysfunction. Transl. Res. 2013, 162, 26-33.
    • (2013) Transl. Res. , vol.162 , pp. 26-33
    • Tang, W.H.1    Shrestha, K.2    Tong, W.3    Wang, Z.4    Troughton, R.W.5    Borowski, A.G.6    Klein, A.L.7    Hazen, S.L.8
  • 151
    • 19344367253 scopus 로고    scopus 로고
    • Stimulated HSP90 binding to eNOS and activation of the PI3-Akt pathway contribute to globular adiponectin-induced NO production: Vasorelaxation in response to globular adiponectin
    • Xi, W.; Satoh, H.; Kase, H.; Suzuki, K.; Hattori, Y. Stimulated HSP90 binding to eNOS and activation of the PI3-Akt pathway contribute to globular adiponectin-induced NO production: Vasorelaxation in response to globular adiponectin. Biochem. Biophys. Res. Commun. 2005, 332, 200-205.
    • (2005) Biochem. Biophys. Res. Commun. , vol.332 , pp. 200-205
    • Xi, W.1    Satoh, H.2    Kase, H.3    Suzuki, K.4    Hattori, Y.5
  • 152
    • 4444280556 scopus 로고    scopus 로고
    • Angiotensin II-induced apoptosis in human endothelial cells is inhibited by adiponectin through restoration of the association between endothelial nitric oxide synthase and heat shock protein 90
    • Lin, L. Y.; Lin, C. Y.; Su, T. C.; Liau, C. S. Angiotensin II-induced apoptosis in human endothelial cells is inhibited by adiponectin through restoration of the association between endothelial nitric oxide synthase and heat shock protein 90. FEBS Lett. 2004, 574, 106-110.
    • (2004) FEBS Lett. , vol.574 , pp. 106-110
    • Lin, L.Y.1    Lin, C.Y.2    Su, T.C.3    Liau, C.S.4
  • 153
    • 69249222525 scopus 로고    scopus 로고
    • Do sauna therapy and exercise act by raising the availability of tetrahydrobiopterin?
    • Pall, M. L. Do sauna therapy and exercise act by raising the availability of tetrahydrobiopterin? Med. Hypotheses 2009, 73, 610-613.
    • (2009) Med. Hypotheses , vol.73 , pp. 610-613
    • Pall, M.L.1
  • 156
    • 0025020589 scopus 로고
    • Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure
    • Morgan, J. P.; Erny, R. E.; Allen, P. D.; Grossman, W.; Gwathmey, J. K. Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure. Circulation 1990, 81, III21-III32.
    • (1990) Circulation , vol.81
    • Morgan, J.P.1    Erny, R.E.2    Allen, P.D.3    Grossman, W.4    Gwathmey, J.K.5
  • 157
    • 84864476166 scopus 로고    scopus 로고
    • Calcium handling in human heart failure-Abnormalities and target for therapy
    • Reuter, H.; Schwinger, R. H. Calcium handling in human heart failure-Abnormalities and target for therapy. Wien. Med. Wochenschr. 2012, 162, 297-301.
    • (2012) Wien. Med. Wochenschr. , vol.162 , pp. 297-301
    • Reuter, H.1    Schwinger, R.H.2
  • 158
    • 84873880957 scopus 로고    scopus 로고
    • Calcium cycling proteins and heart failure: Mechanisms and therapeutics
    • Marks, A. R. Calcium cycling proteins and heart failure: Mechanisms and therapeutics. J. Clin. Investig. 2013, 123, 46-52.
    • (2013) J. Clin. Investig. , vol.123 , pp. 46-52
    • Marks, A.R.1
  • 159
    • 25444450030 scopus 로고    scopus 로고
    • 3-Nitrotyrosine modification of SERCA2a in the aging heart: A distinct signature of the cellular redox environment
    • Knyushko, T. V.; Sharov, V. S.; Williams, T. D.; Schöneich, C.; Bigelow, D. J. 3-Nitrotyrosine modification of SERCA2a in the aging heart: A distinct signature of the cellular redox environment. Biochemistry 2005, 44, 13071-13081.
    • (2005) Biochemistry , vol.44 , pp. 13071-13081
    • Knyushko, T.V.1    Sharov, V.S.2    Williams, T.D.3    Schöneich, C.4    Bigelow, D.J.5
  • 160
    • 0034185616 scopus 로고    scopus 로고
    • Protein oxidation and age-dependent alterations in calcium homeostasis
    • Squier, T. C.; Bigelow, D. J. Protein oxidation and age-dependent alterations in calcium homeostasis. Front. Biosci. 2000, 5, D504-D526.
    • (2000) Front. Biosci. , vol.5
    • Squier, T.C.1    Bigelow, D.J.2
  • 162
    • 0034116320 scopus 로고    scopus 로고
    • Molecular interaction between nitric oxide and ryanodine receptors of skeletal and cardiac sarcoplasmic reticulum
    • Salama, G.; Menshikova, E. V.; Abramson, J. J. Molecular interaction between nitric oxide and ryanodine receptors of skeletal and cardiac sarcoplasmic reticulum. Antioxid. Redox Signal. 2000, 2, 5-16.
    • (2000) Antioxid. Redox Signal. , vol.2 , pp. 5-16
    • Salama, G.1    Menshikova, E.V.2    Abramson, J.J.3
  • 163
    • 21244457292 scopus 로고    scopus 로고
    • Proteomic analysis of protein nitration in aging skeletal muscle and identification of nitrotyrosine-containing sequences in vivo by nanoelectrospray ionization tandem mass spectrometry
    • Kanski, J.; Hong, S. J.; Schöneich, C. Proteomic analysis of protein nitration in aging skeletal muscle and identification of nitrotyrosine-containing sequences in vivo by nanoelectrospray ionization tandem mass spectrometry. J. Biol. Chem. 2005, 280, 24261-24266.
    • (2005) J. Biol. Chem. , vol.280 , pp. 24261-24266
    • Kanski, J.1    Hong, S.J.2    Schöneich, C.3
  • 164
    • 79958135385 scopus 로고    scopus 로고
    • Targeting ryanodine receptors for anti-arrhythmic therapy
    • McCauley, M. D.; Wehrens, X. H. Targeting ryanodine receptors for anti-arrhythmic therapy. Acta Pharmacol. Sin. 2011, 32, 749-757.
    • (2011) Acta Pharmacol. Sin. , vol.32 , pp. 749-757
    • McCauley, M.D.1    Wehrens, X.H.2
  • 165
    • 84870241098 scopus 로고    scopus 로고
    • Altered sarcoplasmic reticulum calcium cycling-Targets for heart failure therapy
    • Kho, C.; Lee, A.; Hajjar, R. J. Altered sarcoplasmic reticulum calcium cycling-Targets for heart failure therapy. Nat. Rev. Cardiol. 2012, 9, 717-733.
    • (2012) Nat. Rev. Cardiol. , vol.9 , pp. 717-733
    • Kho, C.1    Lee, A.2    Hajjar, R.J.3
  • 166
    • 79959720635 scopus 로고    scopus 로고
    • Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention-An in vivo perspective
    • Currie, S.; Elliott, E. B.; Smith, G. L.; Loughrey, C. M. Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention-An in vivo perspective. Pharmacol. Ther. 2011, 131, 204-220.
    • (2011) Pharmacol. Ther. , vol.131 , pp. 204-220
    • Currie, S.1    Elliott, E.B.2    Smith, G.L.3    Loughrey, C.M.4
  • 167
    • 84865813161 scopus 로고    scopus 로고
    • Calpain inhibition preserves talin and attenuates right heart failure in acute pulmonary hypertension
    • Ahmad, H. A.; Lu, L.; Ye, S.; Schwartz, G. G.; Greyson, C. R. Calpain inhibition preserves talin and attenuates right heart failure in acute pulmonary hypertension. Am. J. Respir. Cell Mol. Biol. 2012, 47, 379-386.
    • (2012) Am. J. Respir. Cell Mol. Biol. , vol.47 , pp. 379-386
    • Ahmad, H.A.1    Lu, L.2    Ye, S.3    Schwartz, G.G.4    Greyson, C.R.5
  • 170
    • 37549040627 scopus 로고    scopus 로고
    • Calpain inhibition attenuates right ventricular contractile dysfunction after acute pressure overload
    • Greyson, C. R.; Schwartz, G. G.; Lu, L.; Ye, S.; Helmke, S.; Xu, Y.; Ahmad, H. Calpain inhibition attenuates right ventricular contractile dysfunction after acute pressure overload. J. Mol. Cell. Cardiol. 2008, 44, 59-68.
    • (2008) J. Mol. Cell. Cardiol. , vol.44 , pp. 59-68
    • Greyson, C.R.1    Schwartz, G.G.2    Lu, L.3    Ye, S.4    Helmke, S.5    Xu, Y.6    Ahmad, H.7
  • 171
    • 80051769513 scopus 로고    scopus 로고
    • Tear me down: Role of calpain in the development of cardiac ventricular hypertrophy
    • Patterson, C.; Portbury, A. L.; Schisler, J. C.; Willis, M. S. Tear me down: Role of calpain in the development of cardiac ventricular hypertrophy. Circ. Res. 2011, 109, 453-462.
    • (2011) Circ. Res. , vol.109 , pp. 453-462
    • Patterson, C.1    Portbury, A.L.2    Schisler, J.C.3    Willis, M.S.4
  • 172
    • 67649303340 scopus 로고    scopus 로고
    • Over-expression of calpastatin inhibits calpain activation and attenuates myocardial dysfunction during endotoxaemia
    • Li, X.; Li, Y.; Shan, L.; Shen, E.; Chen, R.; Peng, T. Over-expression of calpastatin inhibits calpain activation and attenuates myocardial dysfunction during endotoxaemia. Cardiovasc. Res. 2009, 83, 72-79.
    • (2009) Cardiovasc. Res. , vol.83 , pp. 72-79
    • Li, X.1    Li, Y.2    Shan, L.3    Shen, E.4    Chen, R.5    Peng, T.6
  • 173
    • 84866685475 scopus 로고    scopus 로고
    • Calpains, mitochondria, and apoptosis
    • Smith, M. A.; Schnellmann, R. G. Calpains, mitochondria, and apoptosis. Cardiovasc. Res. 2012, 96, 32-37.
    • (2012) Cardiovasc. Res. , vol.96 , pp. 32-37
    • Smith, M.A.1    Schnellmann, R.G.2
  • 174
    • 84860623128 scopus 로고    scopus 로고
    • Physiologic and pathophysiologic role of calpain: Implications for the occurrence of atrial fibrillation
    • Bukowska, A.; Lendeckel, U.; Bode-Böger, S. M.; Goette, A. Physiologic and pathophysiologic role of calpain: Implications for the occurrence of atrial fibrillation. Cardiovasc. Ther. 2012, 30, e115-e127.
    • (2012) Cardiovasc. Ther. , vol.30
    • Bukowska, A.1    Lendeckel, U.2    Bode-Böger, S.M.3    Goette, A.4
  • 176
    • 84871531329 scopus 로고    scopus 로고
    • Proteolysis by endogenous calpain I leads to the activation of calcineurin in human heart
    • Wang, J. C.; Zhao, Y.; Li, X. D.; Zhou, N. N.; Sun, H.; Sun, Y. Y. Proteolysis by endogenous calpain I leads to the activation of calcineurin in human heart. Clin. Lab. 2012, 58, 1145-1152.
    • (2012) Clin. Lab. , vol.58 , pp. 1145-1152
    • Wang, J.C.1    Zhao, Y.2    Li, X.D.3    Zhou, N.N.4    Sun, H.5    Sun, Y.Y.6
  • 177
    • 84862001882 scopus 로고    scopus 로고
    • Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1. 5 gating by multiple phosphorylation sites
    • Ashpole, N. M.; Herren, A. W.; Ginsburg, K. S.; Brogan, J. D.; Johnson, D. E.; Cummins, T. R.; Bers, D. M.; Hudmon, A. Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1. 5 gating by multiple phosphorylation sites. J. Biol. Chem. 2012, 287, 19856-19869.
    • (2012) J. Biol. Chem. , vol.287 , pp. 19856-19869
    • Ashpole, N.M.1    Herren, A.W.2    Ginsburg, K.S.3    Brogan, J.D.4    Johnson, D.E.5    Cummins, T.R.6    Bers, D.M.7    Hudmon, A.8
  • 178
    • 84874256463 scopus 로고    scopus 로고
    • Crucial role for Ca2+/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation
    • Hamdani, N.; Krysiak, J.; Kreusser, M. M.; Neef, S.; Dos Remedios, C. G.; Maier, L. S.; Krüger, M.; Backs, J.; Linke, W. A. Crucial role for Ca2+/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation. Circ. Res. 2013, 112, 664-674.
    • (2013) Circ. Res. , vol.112 , pp. 664-674
    • Hamdani, N.1    Krysiak, J.2    Kreusser, M.M.3    Neef, S.4    Dos Remedios, C.G.5    Maier, L.S.6    Krüger, M.7    Backs, J.8    Linke, W.A.9
  • 180
    • 84876326824 scopus 로고    scopus 로고
    • The Ca-calmodulin dependent kinase II: A promising target for future antiarrhythmic therapies?
    • Fischer, T. H.; Neef, S.; Maier, L. S. The Ca-calmodulin dependent kinase II: A promising target for future antiarrhythmic therapies? J. Mol. Cell. Cardiol. 2013, 58, 182-187.
    • (2013) J. Mol. Cell. Cardiol. , vol.58 , pp. 182-187
    • Fischer, T.H.1    Neef, S.2    Maier, L.S.3
  • 182
    • 78549243374 scopus 로고    scopus 로고
    • Sequential alterations in Akt, GSK3β, and calcineurin signalling in the mouse left ventricle after thoracic aortic constriction
    • Prévilon, M.; Pezet, M.; Dachez, C.; Mercadier, J. J.; Rouet-Benzineb, P. Sequential alterations in Akt, GSK3β, and calcineurin signalling in the mouse left ventricle after thoracic aortic constriction. Can. J. Physiol. Pharmacol. 2010, 88, 1093-1101.
    • (2010) Can. J. Physiol. Pharmacol. , vol.88 , pp. 1093-1101
    • Prévilon, M.1    Pezet, M.2    Dachez, C.3    Mercadier, J.J.4    Rouet-Benzineb, P.5
  • 183
    • 84870691785 scopus 로고    scopus 로고
    • Electrical field stimulation induces cardiac fibroblast proliferation through the calcineurin-NFAT pathway
    • Chen, Q. Q.; Zhang, W.; Chen, X. F.; Bao, Y. J.; Wang, J.; Zhu, W. Z. Electrical field stimulation induces cardiac fibroblast proliferation through the calcineurin-NFAT pathway. Can. J. Physiol. Pharmacol. 2012, 90, 1611-1622.
    • (2012) Can. J. Physiol. Pharmacol. , vol.90 , pp. 1611-1622
    • Chen, Q.Q.1    Zhang, W.2    Chen, X.F.3    Bao, Y.J.4    Wang, J.5    Zhu, W.Z.6
  • 185
    • 81355132744 scopus 로고    scopus 로고
    • Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes
    • Lunde, I. G.; Kvaløy, H.; Austbø, B.; Christensen, G.; Carlson, C. R. Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes. J. Appl. Physiol. 2011, 111, 1278-1289.
    • (2011) J. Appl. Physiol. , vol.111 , pp. 1278-1289
    • Lunde, I.G.1    Kvaløy, H.2    Austbø, B.3    Christensen, G.4    Carlson, C.R.5
  • 186
    • 0032745167 scopus 로고    scopus 로고
    • Positive inotropic action of NMDA receptor antagonist (+)-MK801 in rat heart
    • Huang, C. F.; Su, M. J. Positive inotropic action of NMDA receptor antagonist (+)-MK801 in rat heart. J. Biomed. Sci. 1999, 6, 387-398.
    • (1999) J. Biomed. Sci. , vol.6 , pp. 387-398
    • Huang, C.F.1    Su, M.J.2
  • 187
    • 0037135178 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate receptor blockade by dizocilpine prevents stress-induced sudden death in cardiomyopathic hamsters
    • Matsuoka, N.; Kodama, H.; Arakawa, H.; Yamaguchi, I. N-Methyl-D-aspartate receptor blockade by dizocilpine prevents stress-induced sudden death in cardiomyopathic hamsters. Brain Res. 2002, 944, 200-204.
    • (2002) Brain Res. , vol.944 , pp. 200-204
    • Matsuoka, N.1    Kodama, H.2    Arakawa, H.3    Yamaguchi, I.4
  • 190
    • 47249109410 scopus 로고    scopus 로고
    • Mitochondrial MMP activation, dysfunction and arrhythmogenesis in hyperhomocysteinemia
    • Moshal, K. S.; Metreveli, N.; Frank, I.; Tyagi, S. C. Mitochondrial MMP activation, dysfunction and arrhythmogenesis in hyperhomocysteinemia. Curr. Vasc. Pharmacol. 2008, 6, 84-92.
    • (2008) Curr. Vasc. Pharmacol. , vol.6 , pp. 84-92
    • Moshal, K.S.1    Metreveli, N.2    Frank, I.3    Tyagi, S.C.4
  • 192
    • 36849000444 scopus 로고    scopus 로고
    • NMDA receptor activation induces mitochondrial dysfunction, oxidative stress and apoptosis in cultured neonatal rat cardiomyocytes
    • Gao, X.; Xu, X.; Pang, J.; Zhang, C.; Ding, J. M.; Peng, X.; Liu, Y.; Cao, J. M. NMDA receptor activation induces mitochondrial dysfunction, oxidative stress and apoptosis in cultured neonatal rat cardiomyocytes. Physiol. Res. 2007, 56, 559-569.
    • (2007) Physiol. Res. , vol.56 , pp. 559-569
    • Gao, X.1    Xu, X.2    Pang, J.3    Zhang, C.4    Ding, J.M.5    Peng, X.6    Liu, Y.7    Cao, J.M.8
  • 194
    • 14844284575 scopus 로고    scopus 로고
    • Evaluation of cardiac lesions and risk factors associated with myocarditis and dilated cardiomyopathy in southern sea otters (Enhydra lutris nereis)
    • Kreuder, C.; Miller, M. A.; Lowenstine, L. J.; Conrad, P. A.; Carpenter, T. E.; Jessup, D. A.; Mazet, J. A. Evaluation of cardiac lesions and risk factors associated with myocarditis and dilated cardiomyopathy in southern sea otters (Enhydra lutris nereis). Am. J. Vet. Res. 2005, 66, 289-299.
    • (2005) Am. J. Vet. Res. , vol.66 , pp. 289-299
    • Kreuder, C.1    Miller, M.A.2    Lowenstine, L.J.3    Conrad, P.A.4    Carpenter, T.E.5    Jessup, D.A.6    Mazet, J.A.7
  • 195
    • 77958087459 scopus 로고    scopus 로고
    • TRP-ing up heart and vessels: Canonical transient receptor potential channels and cardiovascular disease
    • Rowell, J.; Koitabashi, N.; Kass, D. A. TRP-ing up heart and vessels: Canonical transient receptor potential channels and cardiovascular disease. J. Cardiovasc. Transl. Res. 2010, 3, 516-524.
    • (2010) J. Cardiovasc. Transl. Res. , vol.3 , pp. 516-524
    • Rowell, J.1    Koitabashi, N.2    Kass, D.A.3
  • 197
    • 84870562339 scopus 로고    scopus 로고
    • Cytoskeletal regulation of TRPC channels in the cardiorenal system
    • Stiber, J. A.; Tang, Y.; Li, T.; Rosenberg, P. B. Cytoskeletal regulation of TRPC channels in the cardiorenal system. Curr. Hypertens. Rep. 2012, 14, 492-497.
    • (2012) Curr. Hypertens. Rep. , vol.14 , pp. 492-497
    • Stiber, J.A.1    Tang, Y.2    Li, T.3    Rosenberg, P.B.4
  • 201
    • 33845597014 scopus 로고    scopus 로고
    • Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling
    • Bush, E. W.; Hood, D. B.; Papst, P. J.; Chapo, J. A.; Minobe, W.; Bristow, M. R.; Olson, E. N.; McKinsey, T. A. Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling. J. Biol. Chem. 2006, 281, 33487-33496.
    • (2006) J. Biol. Chem. , vol.281 , pp. 33487-33496
    • Bush, E.W.1    Hood, D.B.2    Papst, P.J.3    Chapo, J.A.4    Minobe, W.5    Bristow, M.R.6    Olson, E.N.7    McKinsey, T.A.8
  • 203
    • 33749338744 scopus 로고    scopus 로고
    • Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart
    • Nakayama, H.; Wilkin, B. J.; Bodi, I.; Molkentin, J. D. Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart. FASEB J. 2006, 20, 1660-1670.
    • (2006) FASEB J. , vol.20 , pp. 1660-1670
    • Nakayama, H.1    Wilkin, B.J.2    Bodi, I.3    Molkentin, J.D.4
  • 204
    • 77951071535 scopus 로고    scopus 로고
    • TRPC channels are necessary mediators of pathologic cardiac hypertrophy
    • Wu, X.; Eder, P.; Chang, B.; Molkentin, J. D. TRPC channels are necessary mediators of pathologic cardiac hypertrophy. Proc. Natl. Acad. Sci. USA 2010, 107, 7000-7005.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 7000-7005
    • Wu, X.1    Eder, P.2    Chang, B.3    Molkentin, J.D.4
  • 206
    • 84858259346 scopus 로고    scopus 로고
    • Transient receptor potential melastatin 4 inhibitor 9-phenanthrol abolishes arrhythmias induced by hypoxia and re-oxygenation in mouse ventricle
    • Simard, C.; Sallé, L.; Rouet, R.; Guinamard, R. Transient receptor potential melastatin 4 inhibitor 9-phenanthrol abolishes arrhythmias induced by hypoxia and re-oxygenation in mouse ventricle. Br. J. Pharmacol. 2012, 165, 2354-2364.
    • (2012) Br. J. Pharmacol. , vol.165 , pp. 2354-2364
    • Simard, C.1    Sallé, L.2    Rouet, R.3    Guinamard, R.4
  • 207
    • 79959458491 scopus 로고    scopus 로고
    • TRPA1 and sympathetic activation contribute to increased risk of triggered cardiac arrhythmias in hypertensive rats exposed to diesel exhaust
    • Hazari, M. S.; Haykal-Coates, N.; Winsett, D. W.; Krantz, Q. T.; King, C.; Costa, D. L.; Farraj, A. K. TRPA1 and sympathetic activation contribute to increased risk of triggered cardiac arrhythmias in hypertensive rats exposed to diesel exhaust. Environ. Health Perspect. 2011, 119, 951-957.
    • (2011) Environ. Health Perspect. , vol.119 , pp. 951-957
    • Hazari, M.S.1    Haykal-Coates, N.2    Winsett, D.W.3    Krantz, Q.T.4    King, C.5    Costa, D.L.6    Farraj, A.K.7
  • 208
    • 84865396310 scopus 로고    scopus 로고
    • Whole and particle-free diesel exhausts differentially affect cardiac electrophysiology, blood pressure, and autonomic balance in heart failure-prone rats
    • Carll, A. P.; Hazari, M. S.; Perez, C. M.; Krantz, Q. T.; King, C. J.; Winsett, D. W.; Costa, D. L.; Farraj, A. K. Whole and particle-free diesel exhausts differentially affect cardiac electrophysiology, blood pressure, and autonomic balance in heart failure-prone rats. Toxicol. Sci. 2012, 128, 490-499.
    • (2012) Toxicol. Sci. , vol.128 , pp. 490-499
    • Carll, A.P.1    Hazari, M.S.2    Perez, C.M.3    Krantz, Q.T.4    King, C.J.5    Winsett, D.W.6    Costa, D.L.7    Farraj, A.K.8
  • 209
    • 80055118501 scopus 로고    scopus 로고
    • Intracellular calcium overloading and oxidative stress in cardiomyocyte necrosis via a mitochondriocentric signal-transducer-effector pathway
    • Shaheen, M.; Cheema, Y.; Shahbaz, A. U.; Bhattacharya, S. K.; Weber, K. T. Intracellular calcium overloading and oxidative stress in cardiomyocyte necrosis via a mitochondriocentric signal-transducer-effector pathway. Exp. Clin. Cardiol. 2011, 16, 109-115.
    • (2011) Exp. Clin. Cardiol. , vol.16 , pp. 109-115
    • Shaheen, M.1    Cheema, Y.2    Shahbaz, A.U.3    Bhattacharya, S.K.4    Weber, K.T.5
  • 210
    • 19344365072 scopus 로고    scopus 로고
    • 2+ channels in endothelin-1 function
    • 2+ channels in endothelin-1 function. Cell. Signal. 2005, 17, 911-916.
    • (2005) Cell. Signal. , vol.17 , pp. 911-916
    • Kawanabe, Y.1    Nauli, S.M.2
  • 212
    • 0030811113 scopus 로고    scopus 로고
    • iNOS expression and nitrotyrosine formation in the myocardium in response to inflammation is controlled by the interferon regulatory factor 1
    • Bachmaier, K.; Neu, N.; Pummerer, C.; Duncan, G. S.; Mak, T. W.; Matsuyama, T.; Penninger, J. M. iNOS expression and nitrotyrosine formation in the myocardium in response to inflammation is controlled by the interferon regulatory factor 1. Circulation 1997, 96, 585-591.
    • (1997) Circulation , vol.96 , pp. 585-591
    • Bachmaier, K.1    Neu, N.2    Pummerer, C.3    Duncan, G.S.4    Mak, T.W.5    Matsuyama, T.6    Penninger, J.M.7
  • 213
    • 0343962205 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase in experimental viral myocarditis
    • Glück, B.; Merkle, I.; Dornberger, G.; Stelzner, A. Expression of inducible nitric oxide synthase in experimental viral myocarditis. Herz 2000, 25, 255-260.
    • (2000) Herz , vol.25 , pp. 255-260
    • Glück, B.1    Merkle, I.2    Dornberger, G.3    Stelzner, A.4
  • 214
    • 84881218944 scopus 로고    scopus 로고
    • Cardiac and respiratory dysfunction in duchenne muscular dystrophy and the role of second messengers
    • Mosqueira, M.; Zeiger, U.; Förderer, M.; Brinkmeier, H.; Fink, R. H. Cardiac and respiratory dysfunction in duchenne muscular dystrophy and the role of second messengers. Med. Res. Rev. 2013, 33, 1174-1213.
    • (2013) Med. Res. Rev. , vol.33 , pp. 1174-1213
    • Mosqueira, M.1    Zeiger, U.2    Förderer, M.3    Brinkmeier, H.4    Fink, R.H.5
  • 215
    • 80052766582 scopus 로고    scopus 로고
    • Pathophysiology and therapy of cardiac dysfunction in Duchenne muscular dystrophy
    • Judge, D. P.; Kass, D. A.; Thompson, W. R.; Wagner, K. R. Pathophysiology and therapy of cardiac dysfunction in Duchenne muscular dystrophy. Am. J. Cardiovasc. Drugs 2011, 11, 287-294.
    • (2011) Am. J. Cardiovasc. Drugs , vol.11 , pp. 287-294
    • Judge, D.P.1    Kass, D.A.2    Thompson, W.R.3    Wagner, K.R.4
  • 217
    • 84857540652 scopus 로고    scopus 로고
    • Differential sensitivity to LPS-induced myocardial dysfunction in the isolated brown Norway and Dahl S rat hearts: Roles of mitochondrial function, NF-κB activation, and TNF-α production
    • An, J.; Du, J.; Wei, N.; Guan, T.; Camara, A. K.; Shi, Y. Differential sensitivity to LPS-induced myocardial dysfunction in the isolated brown Norway and Dahl S rat hearts: Roles of mitochondrial function, NF-κB activation, and TNF-α production. Shock 2012, 37, 325-332.
    • (2012) Shock , vol.37 , pp. 325-332
    • An, J.1    Du, J.2    Wei, N.3    Guan, T.4    Camara, A.K.5    Shi, Y.6
  • 218
    • 0035198828 scopus 로고    scopus 로고
    • Rapid endotoxin-induced alterations in myocardial calcium handling: Obligatory role of cardiac TNF-alpha
    • Stamm, C.; Cowan, D. B.; Friehs, I.; Noria, S.; del Nido, P. J.; McGowan, F. X., Jr. Rapid endotoxin-induced alterations in myocardial calcium handling: Obligatory role of cardiac TNF-alpha. Anesthesiology 2001, 95, 1396-1405.
    • (2001) Anesthesiology , vol.95 , pp. 1396-1405
    • Stamm, C.1    Cowan, D.B.2    Friehs, I.3    Noria, S.4    del Nido, P.J.5    McGowan Jr., F.X.6
  • 222
    • 5344247921 scopus 로고    scopus 로고
    • Mitochondrial nitric oxide metabolism in rat muscle during endotoxemia
    • Alvarez, S.; Boveris, A. Mitochondrial nitric oxide metabolism in rat muscle during endotoxemia. Free Radic. Biol. Med. 2004, 37, 1472-1478.
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 1472-1478
    • Alvarez, S.1    Boveris, A.2
  • 224
    • 77954214321 scopus 로고    scopus 로고
    • Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy
    • Pepe, M.; Mamdani, M.; Zentilin, L.; Csiszar, A.; Qanud, K.; Zacchigna, S.; Ungvari, Z.; Puligadda, U.; Moimas, S.; Xu, X.; et al. Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy. Circ. Res. 2010, 106, 1893-1903.
    • (2010) Circ. Res. , vol.106 , pp. 1893-1903
    • Pepe, M.1    Mamdani, M.2    Zentilin, L.3    Csiszar, A.4    Qanud, K.5    Zacchigna, S.6    Ungvari, Z.7    Puligadda, U.8    Moimas, S.9    Xu, X.10
  • 225
    • 84857641624 scopus 로고    scopus 로고
    • Subcellular structures and function of myocytes impaired during heart failure are restored by cardiac resynchronization therapy
    • Sachse, F. B.; Torres, N. S.; Savio-Galimberti, E.; Aiba, T.; Kass, D. A.; Tomaselli, G. F.; Bridge, J. H. Subcellular structures and function of myocytes impaired during heart failure are restored by cardiac resynchronization therapy. Circ. Res. 2012, 110, 588-597.
    • (2012) Circ. Res. , vol.110 , pp. 588-597
    • Sachse, F.B.1    Torres, N.S.2    Savio-Galimberti, E.3    Aiba, T.4    Kass, D.A.5    Tomaselli, G.F.6    Bridge, J.H.7
  • 227
    • 84867491738 scopus 로고    scopus 로고
    • Mechanisms in endocrinology: Heart failure and thyroid dysfunction
    • Biondi, B. Mechanisms in endocrinology: Heart failure and thyroid dysfunction. Eur. J. Endocrinol. 2012, 167, 609-618.
    • (2012) Eur. J. Endocrinol. , vol.167 , pp. 609-618
    • Biondi, B.1
  • 229
    • 35448979131 scopus 로고    scopus 로고
    • Mitochondrial and energetic cardiac phenotype in hypothyroid rat. Relevance to heart failure
    • Athéa, Y.; Garnier, A.; Fortin, D.; Bahi, L.; Veksler, V.; Ventura-Clapier, R. Mitochondrial and energetic cardiac phenotype in hypothyroid rat. Relevance to heart failure. Pflugers Arch. 2007, 455, 431-442.
    • (2007) Pflugers Arch. , vol.455 , pp. 431-442
    • Athéa, Y.1    Garnier, A.2    Fortin, D.3    Bahi, L.4    Veksler, V.5    Ventura-Clapier, R.6
  • 230
    • 38949206872 scopus 로고    scopus 로고
    • Post-thyroidectomy thyroxine replacement dose in patients with or without compensated heart failure: The role of cytokines
    • Papanas, N.; Papatheodorou, K.; Papazoglou, D.; Gioka, T.; Antonoglou, C.; Kotsiou, S.; Maltezos, E. Post-thyroidectomy thyroxine replacement dose in patients with or without compensated heart failure: The role of cytokines. Cytokine 2008, 41, 121-126.
    • (2008) Cytokine , vol.41 , pp. 121-126
    • Papanas, N.1    Papatheodorou, K.2    Papazoglou, D.3    Gioka, T.4    Antonoglou, C.5    Kotsiou, S.6    Maltezos, E.7
  • 231
    • 0023608097 scopus 로고
    • Lipid peroxidation and free radical scavengers in thyroid dysfunction in the rat: A possible mechanism of injury to heart and skeletal muscle in hyperthyroidism
    • Asayama, K.; Dobashi, K.; Hayashibe, H.; Megata, Y.; Kato, K. Lipid peroxidation and free radical scavengers in thyroid dysfunction in the rat: A possible mechanism of injury to heart and skeletal muscle in hyperthyroidism. Endocrinology 1987, 121, 2112-2118.
    • (1987) Endocrinology , vol.121 , pp. 2112-2118
    • Asayama, K.1    Dobashi, K.2    Hayashibe, H.3    Megata, Y.4    Kato, K.5
  • 232
    • 0016042832 scopus 로고
    • Alterations in the fine structure of cardiac muscle mitochondria induced by hyperthyroidism
    • Callas, G.; Hayes, J. R. Alterations in the fine structure of cardiac muscle mitochondria induced by hyperthyroidism. Anat. Rec. 1974, 178, 539-549.
    • (1974) Anat. Rec. , vol.178 , pp. 539-549
    • Callas, G.1    Hayes, J.R.2
  • 233
    • 84868687470 scopus 로고    scopus 로고
    • Ablation of ALCAT1 mitigates hypertrophic cardiomyopathy through effects on oxidative stress and mitophagy
    • Liu, X.; Ye, B.; Miller, S.; Yuan, H.; Zhang, H.; Tian, L.; Nie, J.; Imae, R.; Arai, H.; Li, Y.; et al. Ablation of ALCAT1 mitigates hypertrophic cardiomyopathy through effects on oxidative stress and mitophagy. Mol. Cell. Biol. 2012, 32, 4493-4504.
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 4493-4504
    • Liu, X.1    Ye, B.2    Miller, S.3    Yuan, H.4    Zhang, H.5    Tian, L.6    Nie, J.7    Imae, R.8    Arai, H.9    Li, Y.10
  • 234
  • 241
    • 79953042525 scopus 로고    scopus 로고
    • Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species
    • Hosseinzadeh, L.; Behravan, J.; Mosaffa, F.; Bahrami, G.; Bahrami, A.; Karimi, G. Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species. Food Chem. Toxicol. 2011, 49, 1102-1109.
    • (2011) Food Chem. Toxicol. , vol.49 , pp. 1102-1109
    • Hosseinzadeh, L.1    Behravan, J.2    Mosaffa, F.3    Bahrami, G.4    Bahrami, A.5    Karimi, G.6
  • 242
    • 78249281033 scopus 로고    scopus 로고
    • Allicin protects against cardiac hypertrophy and fibrosis via attenuating reactive oxygen species-dependent signaling pathways
    • Liu, C.; Cao, F.; Tang, Q. Z.; Yan, L.; Dong, Y. G.; Zhu, L. H.; Wang, L.; Bian, Z. Y.; Li, H. Allicin protects against cardiac hypertrophy and fibrosis via attenuating reactive oxygen species-dependent signaling pathways. J. Nutr. Biochem. 2010, 21, 1238-1250.
    • (2010) J. Nutr. Biochem. , vol.21 , pp. 1238-1250
    • Liu, C.1    Cao, F.2    Tang, Q.Z.3    Yan, L.4    Dong, Y.G.5    Zhu, L.H.6    Wang, L.7    Bian, Z.Y.8    Li, H.9
  • 243
    • 68949210666 scopus 로고    scopus 로고
    • Redox regulation, NF-kappaB, and atrial fibrillation
    • Gao, G.; Dudley, S. C., Jr. Redox regulation, NF-kappaB, and atrial fibrillation. Antioxid. Redox Signal. 2009, 11, 2265-2277.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 2265-2277
    • Gao, G.1    Dudley Jr., S.C.2
  • 246
    • 80053990951 scopus 로고    scopus 로고
    • Regulation of kinase cascade activation and heat shock protein expression by poly(ADP-ribose) polymerase inhibition in doxorubicin-induced heart failure
    • Bartha, E.; Solti, I.; Szabo, A.; Olah, G.; Magyar, K.; Szabados, E.; Kalai, T.; Hideg, K.; Toth, K.; Gero, D.; et al. Regulation of kinase cascade activation and heat shock protein expression by poly(ADP-ribose) polymerase inhibition in doxorubicin-induced heart failure. J. Cardiovasc. Pharmacol. 2011, 58, 380-391.
    • (2011) J. Cardiovasc. Pharmacol. , vol.58 , pp. 380-391
    • Bartha, E.1    Solti, I.2    Szabo, A.3    Olah, G.4    Magyar, K.5    Szabados, E.6    Kalai, T.7    Hideg, K.8    Toth, K.9    Gero, D.10
  • 249
    • 14344266084 scopus 로고    scopus 로고
    • Poly(ADP-Ribose) polymerase promotes cardiac remodeling, contractile failure, and translocation of apoptosis-inducing factor in a murine experimental model of aortic banding and heart failure
    • Xiao, C. Y.; Chen, M.; Zsengellér, Z.; Li, H.; Kiss, L.; Kollai, M.; Szabó, C. Poly(ADP-Ribose) polymerase promotes cardiac remodeling, contractile failure, and translocation of apoptosis-inducing factor in a murine experimental model of aortic banding and heart failure. J. Pharmacol. Exp. Ther. 2005, 312, 891-898.
    • (2005) J. Pharmacol. Exp. Ther. , vol.312 , pp. 891-898
    • Xiao, C.Y.1    Chen, M.2    Zsengellér, Z.3    Li, H.4    Kiss, L.5    Kollai, M.6    Szabó, C.7
  • 251
  • 252
    • 63849201518 scopus 로고    scopus 로고
    • Role of xanthine oxidoreductase in cardiac nitroso-redox imbalance
    • Tziomalos, K.; Hare, J. M. Role of xanthine oxidoreductase in cardiac nitroso-redox imbalance. Front. Biosci. 2009, 14, 237-262.
    • (2009) Front. Biosci. , vol.14 , pp. 237-262
    • Tziomalos, K.1    Hare, J.M.2
  • 253
    • 34548850881 scopus 로고    scopus 로고
    • Role of xanthine oxidoreductase in the reversal of diastolic heart failure by candesartan in the salt-sensitive hypertensive rat
    • Yamamoto, E.; Kataoka, K.; Yamashita, T.; Tokutomi, Y.; Dong, Y. F.; Matsuba, S.; Ogawa, H.; Kim-Mitsuyama, S. Role of xanthine oxidoreductase in the reversal of diastolic heart failure by candesartan in the salt-sensitive hypertensive rat. Hypertension 2007, 50, 657-662.
    • (2007) Hypertension , vol.50 , pp. 657-662
    • Yamamoto, E.1    Kataoka, K.2    Yamashita, T.3    Tokutomi, Y.4    Dong, Y.F.5    Matsuba, S.6    Ogawa, H.7    Kim-Mitsuyama, S.8
  • 254
    • 77950363801 scopus 로고    scopus 로고
    • Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure
    • Rehsia, N. S.; Dhalla, N. S. Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure. Heart Fail. Rev. 2010, 15, 85-101.
    • (2010) Heart Fail. Rev. , vol.15 , pp. 85-101
    • Rehsia, N.S.1    Dhalla, N.S.2
  • 255
    • 84871585276 scopus 로고    scopus 로고
    • The role of the paracrine/autocrine mediator endothelin-1 in regulation of cardiac contractility and growth
    • Drawnel, F. M.; Archer, C. R.; Roderick, H. L. The role of the paracrine/autocrine mediator endothelin-1 in regulation of cardiac contractility and growth. Br. J. Pharmacol. 2013, 168, 296-317.
    • (2013) Br. J. Pharmacol. , vol.168 , pp. 296-317
    • Drawnel, F.M.1    Archer, C.R.2    Roderick, H.L.3
  • 256
    • 84864182366 scopus 로고    scopus 로고
    • Regulation of sarco(endo)plasmic reticulum Ca2+-ATPase and calsequestrin gene expression in the heart
    • Zarain-Herzberg, A.; Estrada-Avilés, R.; Fragoso-Medina, J. Regulation of sarco(endo)plasmic reticulum Ca2+-ATPase and calsequestrin gene expression in the heart. Can. J. Physiol. Pharmacol. 2012, 90, 1017-1028.
    • (2012) Can. J. Physiol. Pharmacol. , vol.90 , pp. 1017-1028
    • Zarain-Herzberg, A.1    Estrada-Avilés, R.2    Fragoso-Medina, J.3
  • 257
    • 7244239393 scopus 로고    scopus 로고
    • Endothelin-1 mediates cardiac mast cell degranulation, matrix metalloproteinase activation, and myocardial remodeling in rats
    • Murray, D. B.; Gardner, J. D.; Brower, G. L.; Janicki, J. S. Endothelin-1 mediates cardiac mast cell degranulation, matrix metalloproteinase activation, and myocardial remodeling in rats. Am. J. Physiol. Heart Circ. Physiol. 2004, 287, H2295-H2299.
    • (2004) Am. J. Physiol. Heart Circ. Physiol. , vol.287
    • Murray, D.B.1    Gardner, J.D.2    Brower, G.L.3    Janicki, J.S.4
  • 258
    • 41549118425 scopus 로고    scopus 로고
    • Effects of nonselective endothelin-1 receptor antagonism on cardiac mast cell-mediated ventricular remodeling in rats
    • Murray, D. B.; Gardner, J. D.; Brower, G. L.; Janicki, J. S. Effects of nonselective endothelin-1 receptor antagonism on cardiac mast cell-mediated ventricular remodeling in rats. Am. J. Physiol. Heart Circ. Physiol. 2008, 294, H1251-H1257.
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294
    • Murray, D.B.1    Gardner, J.D.2    Brower, G.L.3    Janicki, J.S.4
  • 260
    • 84874394223 scopus 로고    scopus 로고
    • Central Rho kinase inhibition restores baroreflex sensitivity and angiotensin II type 1 receptor protein imbalance in conscious rabbits with chronic heart failure
    • Haack, K. K.; Gao, L.; Schiller, A. M.; Curry, P. L.; Pellegrino, P. R.; Zucker, I. H. Central Rho kinase inhibition restores baroreflex sensitivity and angiotensin II type 1 receptor protein imbalance in conscious rabbits with chronic heart failure. Hypertension 2013, 61, 723-729.
    • (2013) Hypertension , vol.61 , pp. 723-729
    • Haack, K.K.1    Gao, L.2    Schiller, A.M.3    Curry, P.L.4    Pellegrino, P.R.5    Zucker, I.H.6
  • 262
    • 80053101752 scopus 로고    scopus 로고
    • Rho kinase as a therapeutic target in cardiovascular disease
    • Surma, M.; Wei, L.; Shi, J. Rho kinase as a therapeutic target in cardiovascular disease. Future Cardiol. 2011, 7, 657-671.
    • (2011) Future Cardiol. , vol.7 , pp. 657-671
    • Surma, M.1    Wei, L.2    Shi, J.3
  • 264
    • 79953743688 scopus 로고    scopus 로고
    • Rho-kinase in development and heart failure: Insights from genetic models
    • Shi, J.; Zhang, L.; Wei, L. Rho-kinase in development and heart failure: Insights from genetic models. Pediatr. Cardiol. 2011, 32, 297-304.
    • (2011) Pediatr. Cardiol. , vol.32 , pp. 297-304
    • Shi, J.1    Zhang, L.2    Wei, L.3
  • 265
    • 80051485388 scopus 로고    scopus 로고
    • Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, suppresses isoproterenol-induced heart failure in rats via JNK and ERK1/2 pathways
    • Wang, N.; Guan, P.; Zhang, J. P.; Li, Y. Q.; Chang, Y. Z.; Shi, Z. H.; Wang, F. Y.; Chu, L. Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, suppresses isoproterenol-induced heart failure in rats via JNK and ERK1/2 pathways. J. Cell. Biochem. 2011, 112, 1920-1929.
    • (2011) J. Cell. Biochem. , vol.112 , pp. 1920-1929
    • Wang, N.1    Guan, P.2    Zhang, J.P.3    Li, Y.Q.4    Chang, Y.Z.5    Shi, Z.H.6    Wang, F.Y.7    Chu, L.8
  • 266
    • 80053561902 scopus 로고    scopus 로고
    • Preventive effects of fasudil on adriamycin-induced cardiomyopathy: Possible involvement of inhibition of RhoA/ROCK pathway
    • Wang, N.; Guan, P.; Zhang, J. P.; Chang, Y. Z.; Gu, L. J.; Hao, F. K.; Shi, Z. H.; Wang, F. Y.; Chu, L. Preventive effects of fasudil on adriamycin-induced cardiomyopathy: Possible involvement of inhibition of RhoA/ROCK pathway. Food Chem. Toxicol. 2011, 49, 2975-2982.
    • (2011) Food Chem. Toxicol. , vol.49 , pp. 2975-2982
    • Wang, N.1    Guan, P.2    Zhang, J.P.3    Chang, Y.Z.4    Gu, L.J.5    Hao, F.K.6    Shi, Z.H.7    Wang, F.Y.8    Chu, L.9
  • 267
    • 33747594735 scopus 로고    scopus 로고
    • Endogenous endothelin-1 is required for cardiomyocyte survival in vivo
    • Zhao, X. S.; Pan, W.; Bekeredjian, R.; Shohet, R. V. Endogenous endothelin-1 is required for cardiomyocyte survival in vivo. Circulation 2006, 114, 830-837.
    • (2006) Circulation , vol.114 , pp. 830-837
    • Zhao, X.S.1    Pan, W.2    Bekeredjian, R.3    Shohet, R.V.4
  • 269
    • 77955085839 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration and mechanisms of microglial killing in neurons
    • Brown, G. C.; Neher, J. J. Inflammatory neurodegeneration and mechanisms of microglial killing in neurons. Mol. Neurobiol. 2010, 41, 242-247.
    • (2010) Mol. Neurobiol. , vol.41 , pp. 242-247
    • Brown, G.C.1    Neher, J.J.2
  • 270
    • 0041784698 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
    • Brown, G. C.; Bal-Price, A. Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. Mol. Neurobiol. 2003, 27, 325-355.
    • (2003) Mol. Neurobiol. , vol.27 , pp. 325-355
    • Brown, G.C.1    Bal-Price, A.2
  • 271
    • 79958141073 scopus 로고    scopus 로고
    • Hydralazine and isosorbide dinitrate in heart failure: Historical perspective, mechanisms, and future directions
    • Cole, R. T.; Kalogeropoulos, A. P.; Georgiopoulou, V. V.; Gheorghiade, M.; Quyyumi, A.; Yancy, C.; Butler, J. Hydralazine and isosorbide dinitrate in heart failure: Historical perspective, mechanisms, and future directions. Circulation 2011, 123, 2414-2422.
    • (2011) Circulation , vol.123 , pp. 2414-2422
    • Cole, R.T.1    Kalogeropoulos, A.P.2    Georgiopoulou, V.V.3    Gheorghiade, M.4    Quyyumi, A.5    Yancy, C.6    Butler, J.7
  • 272
    • 77957662777 scopus 로고    scopus 로고
    • Treatment of systolic heart failure in the elderly: An evidence-based review
    • Arif, S. A.; Mergenhagen, K. A.; del Carpio, R. O.; Ho, C. Treatment of systolic heart failure in the elderly: An evidence-based review. Ann. Pharmacother. 2010, 44, 1604-1614.
    • (2010) Ann. Pharmacother. , vol.44 , pp. 1604-1614
    • Arif, S.A.1    Mergenhagen, K.A.2    del Carpio, R.O.3    Ho, C.4
  • 273
    • 84864421166 scopus 로고    scopus 로고
    • Effect of fixed-dose combined isosorbide dinitrate/hydralazine in elderly patients in the African-American heart failure trial
    • A-HeFT Investigators
    • Taylor, A. L.; Sabolinski, M. L.; Tam, S. W.; Ziesche, S.; Ghali, J. K.; Archambault, W. T.; Worcel, M.; Cohn, J. N.; A-HeFT Investigators. Effect of fixed-dose combined isosorbide dinitrate/hydralazine in elderly patients in the African-American heart failure trial. J. Card. Fail. 2012, 18, 600-606.
    • (2012) J. Card. Fail. , vol.18 , pp. 600-606
    • Taylor, A.L.1    Sabolinski, M.L.2    Tam, S.W.3    Ziesche, S.4    Ghali, J.K.5    Archambault, W.T.6    Worcel, M.7    Cohn, J.N.8
  • 276
    • 84860759272 scopus 로고    scopus 로고
    • Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway
    • Huang, W.; Shang, W. L.; Wang, H. D.; Wu, W. W.; Hou, S. X. Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway. Acta Pharmacol. Sin. 2012, 33, 668-674.
    • (2012) Acta Pharmacol. Sin. , vol.33 , pp. 668-674
    • Huang, W.1    Shang, W.L.2    Wang, H.D.3    Wu, W.W.4    Hou, S.X.5
  • 279
    • 77952837883 scopus 로고    scopus 로고
    • Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes
    • Biala, A.; Tauriainen, E.; Siltanen, A.; Shi, J.; Merasto, S.; Louhelainen, M.; Martonen, E.; Finckenberg, P.; Muller, D. N.; Mervaala, E. Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes. Blood Press. 2010, 19, 196-205.
    • (2010) Blood Press. , vol.19 , pp. 196-205
    • Biala, A.1    Tauriainen, E.2    Siltanen, A.3    Shi, J.4    Merasto, S.5    Louhelainen, M.6    Martonen, E.7    Finckenberg, P.8    Muller, D.N.9    Mervaala, E.10
  • 280
    • 84866952221 scopus 로고    scopus 로고
    • Resveratrol regulates N-methyl-D-aspartate receptor expression and suppresses neuroinflammation in morphine-tolerant rats
    • Tsai, R. Y.; Chou, K, Y.; Shen, C. H.; Chien, C. C.; Tsai, W. Y.; Huang, Y. N.; Tao, P. L.; Lin, Y. S.; Wong, C. S. Resveratrol regulates N-methyl-D-aspartate receptor expression and suppresses neuroinflammation in morphine-tolerant rats. Anesth. Analg. 2012, 115, 944-952.
    • (2012) Anesth. Analg. , vol.115 , pp. 944-952
    • Tsai, R.Y.1    Chou, K.Y.2    Shen, C.H.3    Chien, C.C.4    Tsai, W.Y.5    Huang, Y.N.6    Tao, P.L.7    Lin, Y.S.8    Wong, C.S.9
  • 281
    • 78851472360 scopus 로고    scopus 로고
    • Resveratrol modulates astroglial functions: Neuroprotective hypothesis
    • Quincozes-Santos, A.; Gottfried, C. Resveratrol modulates astroglial functions: Neuroprotective hypothesis. Ann. N. Y. Acad. Sci. 2011, 1215, 72-78.
    • (2011) Ann. N.Y. Acad. Sci. , vol.1215 , pp. 72-78
    • Quincozes-Santos, A.1    Gottfried, C.2
  • 284
    • 80052799903 scopus 로고    scopus 로고
    • Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy
    • Sundaresan, N. R.; Pillai, V. B.; Gupta, M. P. Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy. J. Mol. Cell. Cardiol. 2011, 51, 614-618.
    • (2011) J. Mol. Cell. Cardiol. , vol.51 , pp. 614-618
    • Sundaresan, N.R.1    Pillai, V.B.2    Gupta, M.P.3


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