메뉴 건너뛰기




Volumn 89, Issue 1, 2011, Pages 129-138

Cardiomyocyte NF-κB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure

Author keywords

Apoptosis; Cardiac remodelling; ER stress; Heart failure; NF B

Indexed keywords

ALANINE; CHAPERONE; CYTOKINE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SERINE; TRANSCRIPTION FACTOR RELA;

EID: 78650443223     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq274     Document Type: Article
Times cited : (225)

References (34)
  • 3
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-kB signaling: Balancing life and death-a new approach to cancer therapy
    • Luo JL, Kamata H, Karin M. IKK/NF-kB signaling: balancing life and death-a new approach to cancer therapy. J Clin Invest 2005;115:2625-2632.
    • (2005) J Clin Invest , vol.115 , pp. 2625-2632
    • Luo, J.L.1    Kamata, H.2    Karin, M.3
  • 4
    • 26444442450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: Cell life and death decisions
    • Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 2005;115:2656-2664.
    • (2005) J Clin Invest , vol.115 , pp. 2656-2664
    • Xu, C.1    Bailly-Maitre, B.2    Reed, J.C.3
  • 5
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kB
    • Hayden MS, Ghosh S. Signaling to NF-kB. Genes Dev 2004;18:2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 6
    • 0347949510 scopus 로고    scopus 로고
    • Molecular mechanisms of interleukin-10-mediated inhibition of NF-kB activity: A role for p50
    • Driessler F, Venstrom K, Sabat R, Asadullah K, Schottelius AJ. Molecular mechanisms of interleukin-10-mediated inhibition of NF-kB activity: a role for p50. Clin Exp Immunol 2004;135:64-73.
    • (2004) Clin Exp Immunol , vol.135 , pp. 64-73
    • Driessler, F.1    Venstrom, K.2    Sabat, R.3    Asadullah, K.4    Schottelius, A.J.5
  • 7
    • 0036203419 scopus 로고    scopus 로고
    • The phosphorylation status of nuclear NF-kB determines its association with CBP/p300 or HDAC-1
    • Zhong H, May MJ, Jimi E, Ghosh S. The phosphorylation status of nuclear NF-kB determines its association with CBP/p300 or HDAC-1. Mol Cell 2002;9:625-636.
    • (2002) Mol Cell , vol.9 , pp. 625-636
    • Zhong, H.1    May, M.J.2    Jimi, E.3    Ghosh, S.4
  • 8
    • 0037195727 scopus 로고    scopus 로고
    • Inflammatory mediators and the failing heart: Past, present, and the foreseeable future
    • Mann DL. Inflammatory mediators and the failing heart: past, present, and the foreseeable future. Circ Res 2002;91:988-998.
    • (2002) Circ Res , vol.91 , pp. 988-998
    • Mann, D.L.1
  • 9
    • 0034595362 scopus 로고    scopus 로고
    • B-Adrenergic blockade in developing heart failure: Effects on myocardial inflammatory cytokines, nitric oxide, and remodeling
    • Prabhu SD, Chandrasekar B, Murray DR, Freeman GL. b-Adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling. Circulation 2000;101:2103-2109.
    • (2000) Circulation , vol.101 , pp. 2103-2109
    • Prabhu, S.D.1    Chandrasekar, B.2    Murray, D.R.3    Freeman, G.L.4
  • 10
    • 0032516477 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 and activation of nuclear factor-kB in myocardium of patients with congestive heart failure
    • Wong SC, Fukuchi M, Melnyk P, Rodger I, Giaid A. Induction of cyclooxygenase-2 and activation of nuclear factor-kB in myocardium of patients with congestive heart failure. Circulation 1998;98:100-103.
    • (1998) Circulation , vol.98 , pp. 100-103
    • Wong, S.C.1    Fukuchi, M.2    Melnyk, P.3    Rodger, I.4    Giaid, A.5
  • 11
    • 0036135073 scopus 로고    scopus 로고
    • Reversible activation of nuclear factor-kB in human end-stage heart failure after left ventricular mechanical support
    • Grabellus F, Levkau B, Sokoll A, Welp H, Schmid C, Deng MC et al.Reversible activation of nuclear factor-kB in human end-stage heart failure after left ventricular mechanical support. Cardiovasc Res 2002;53:124-130.
    • (2002) Cardiovasc Res , vol.53 , pp. 124-130
    • Grabellus, F.1    Levkau, B.2    Sokoll, A.3    Welp, H.4    Schmid, C.5    Deng, M.C.6
  • 12
    • 4444304017 scopus 로고    scopus 로고
    • Effect of chronic heart failure on nuclear factor kB in peripheral leukocytes
    • Frantz S, Stoerk S, Ok S, Wagner H, Angermann CE, Ertl G et al.Effect of chronic heart failure on nuclear factor kB in peripheral leukocytes. Am J Cardiol 2004;94: 671-673.
    • (2004) Am J Cardiol , vol.94 , pp. 671-673
    • Frantz, S.1    Stoerk, S.2    Ok, S.3    Wagner, H.4    Angermann, C.E.5    Ertl, G.6
  • 13
    • 33748648140 scopus 로고    scopus 로고
    • Absence of NF-kB subunit p50 improves heart failure after myocardial infarction
    • Frantz S, Hu K, Bayer B, Gerondakis S, Strotmann J, Adamek A et al.Absence of NF-kB subunit p50 improves heart failure after myocardial infarction. FASEB J 2006; 20:1918-1920.
    • (2006) FASEB J , vol.20 , pp. 1918-1920
    • Frantz, S.1    Hu, K.2    Bayer, B.3    Gerondakis, S.4    Strotmann, J.5    Adamek, A.6
  • 15
    • 63649110166 scopus 로고    scopus 로고
    • Targeted deletion of nuclear factor kB p50 enhances cardiac remodeling and dysfunction following myocardial infarction
    • Timmers L, van Keulen JK, Hoefer IE, Meijs MF, van Middelaar B, den Ouden K et al.Targeted deletion of nuclear factor kB p50 enhances cardiac remodeling and dysfunction following myocardial infarction. Circ Res 2009;104:699-706.
    • (2009) Circ Res , vol.104 , pp. 699-706
    • Timmers, L.1    Van Keulen, J.K.2    Hoefer, I.E.3    Meijs, M.F.4    Van Middelaar, B.5    Den Ouden, K.6
  • 16
    • 0035142594 scopus 로고    scopus 로고
    • Cardiac-specific abrogation of NF-kB activation in mice by transdominant expression of a mutant IkBa
    • Dawn B, Xuan YT, Marian M, Flaherty MP, Murphree SS, Smith TL et al.Cardiac-specific abrogation of NF-kB activation in mice by transdominant expression of a mutant IkBa. J Mol Cell Cardiol 2001;33:161-173.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 161-173
    • Dawn, B.1    Xuan, Y.T.2    Marian, M.3    Flaherty, M.P.4    Murphree, S.S.5    Smith, T.L.6
  • 18
    • 64549087652 scopus 로고    scopus 로고
    • Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: Role of nuclear factor-kB and inflammatory activation
    • Hamid T, Gu Y, Ortines RV, Bhattacharya C, Wang G, Xuan YT et al.Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: role of nuclear factor-kB and inflammatory activation. Circulation 2009;119:1386-1397.
    • (2009) Circulation , vol.119 , pp. 1386-1397
    • Hamid, T.1    Gu, Y.2    Ortines, R.V.3    Bhattacharya, C.4    Wang, G.5    Xuan, Y.T.6
  • 19
    • 77951878150 scopus 로고    scopus 로고
    • Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart
    • Wang G, Hamid T, Keith RJ, Zhou G, Partridge CR, Xiang X et al.Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart. Circulation 2010; 121:1912-1925.
    • (2010) Circulation , vol.121 , pp. 1912-1925
    • Wang, G.1    Hamid, T.2    Keith, R.J.3    Zhou, G.4    Partridge, C.R.5    Xiang, X.6
  • 20
    • 0032583949 scopus 로고    scopus 로고
    • Differential regulation of IkB kinase a and b by two upstream kinases NF-kB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
    • Nakano H, Shindo M, Sakon S, Nishinaka S, Mihara M, Yagita H et al.Differential regulation of IkB kinase a and b by two upstream kinases, NF-kB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc Natl Acad Sci USA 1998; 95:3537-3542.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3537-3542
    • Nakano, H.1    Shindo, M.2    Sakon, S.3    Nishinaka, S.4    Mihara, M.5    Yagita, H.6
  • 21
    • 36849019121 scopus 로고    scopus 로고
    • Mechanisms of acrolein-induced myocardial dysfunction: Implications for environmental and endogenous aldehyde exposure
    • Luo J, Hill BG, Gu Y, Cai J, Srivastava S, Bhatnagar A et al.Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure. Am J Physiol Heart Circ Physiol 2007;293: H3673-H3684.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Luo, J.1    Hill, B.G.2    Gu, Y.3    Cai, J.4    Srivastava, S.5    Bhatnagar, A.6
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-DDCT method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-DDCT method. Methods 2001;25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 0038637913 scopus 로고    scopus 로고
    • B-Adrenergic receptor blockade modulates Bcl-XS expression and reduces apoptosis in failing myocardium
    • Prabhu SD, Wang G, Luo J, Gu Y, Ping P, Chandrasekar B. b-Adrenergic receptor blockade modulates Bcl-XS expression and reduces apoptosis in failing myocardium. J Mol Cell Cardiol 2003;35:483-493.
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 483-493
    • Prabhu, S.D.1    Wang, G.2    Luo, J.3    Gu, Y.4    Ping, P.5    Chandrasekar, B.6
  • 24
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB
    • Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB. J Clin Invest 2001;107:241-246.
    • (2001) J Clin Invest , vol.107 , pp. 241-246
    • Baldwin, A.S.1
  • 25
    • 0035067368 scopus 로고    scopus 로고
    • Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kB
    • Ravi R, Bedi GC, Engstrom LW, Zeng Q, Mookerjee B, Gelinas C et al.Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kB. Nat Cell Biol 2001;3:409-416.
    • (2001) Nat Cell Biol , vol.3 , pp. 409-416
    • Ravi, R.1    Bedi, G.C.2    Engstrom, L.W.3    Zeng, Q.4    Mookerjee, B.5    Gelinas, C.6
  • 26
    • 0041828937 scopus 로고    scopus 로고
    • Is nuclear factor-kB an attractive therapeutic target for treating cardiac hypertrophy?
    • Purcell NH, Molkentin JD. Is nuclear factor-kB an attractive therapeutic target for treating cardiac hypertrophy? Circulation 2003;108:638-640.
    • (2003) Circulation , vol.108 , pp. 638-640
    • Purcell, N.H.1    Molkentin, J.D.2
  • 27
    • 34547527483 scopus 로고    scopus 로고
    • Tissue-specific effects of the nuclear factor kB subunit p50 on myocardial ischemia-reperfusion injury
    • Frantz S, Tillmanns J, Kuhlencordt PJ, Schmidt I, Adamek A, Dienesch C et al.Tissue-specific effects of the nuclear factor kB subunit p50 on myocardial ischemia-reperfusion injury. Am J Pathol 2007;171:507-512.
    • (2007) Am J Pathol , vol.171 , pp. 507-512
    • Frantz, S.1    Tillmanns, J.2    Kuhlencordt, P.J.3    Schmidt, I.4    Adamek, A.5    Dienesch, C.6
  • 28
    • 67949112796 scopus 로고    scopus 로고
    • The IkB kinase b/nuclear factor kB signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression
    • Hikoso S, Yamaguchi O, Nakano Y, Takeda T, Omiya S, Mizote I et al.The IkB kinase b/nuclear factor kB signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression. Circ Res 2009;105:70-79.
    • (2009) Circ Res , vol.105 , pp. 70-79
    • Hikoso, S.1    Yamaguchi, O.2    Nakano, Y.3    Takeda, T.4    Omiya, S.5    Mizote, I.6
  • 29
    • 74049097242 scopus 로고    scopus 로고
    • Antioxidant amelioration of dilated cardiomyopathy caused by conditional deletion of NEMO/IKKg in cardiomyocytes
    • Kratsios P, Huth M, Temmerman L, Salimova E, Al Banchaabouchi M, Sgoifo A et al.Antioxidant amelioration of dilated cardiomyopathy caused by conditional deletion of NEMO/IKKg in cardiomyocytes. Circ Res 2010;106:133-144.
    • (2010) Circ Res , vol.106 , pp. 133-144
    • Kratsios, P.1    Huth, M.2    Temmerman, L.3    Salimova, E.4    Al Banchaabouchi, M.5    Sgoifo, A.6
  • 30
    • 68749103771 scopus 로고    scopus 로고
    • The NF-kB-independent functions of IKK subunits in immunity and cancer
    • Chariot A. The NF-kB-independent functions of IKK subunits in immunity and cancer. Trends Cell Biol 2009;19:404-413.
    • (2009) Trends Cell Biol , vol.19 , pp. 404-413
    • Chariot, A.1
  • 31
    • 0035811062 scopus 로고    scopus 로고
    • Activation of NF-kB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes
    • Purcell NH, Tang G, Yu C, Mercurio F, DiDonato JA, Lin A. Activation of NF-kB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proc Natl Acad Sci USA 2001;98:6668-6673.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6668-6673
    • Purcell, N.H.1    Tang, G.2    Yu, C.3    Mercurio, F.4    Didonato, J.A.5    Lin, A.6
  • 32
    • 4043076224 scopus 로고    scopus 로고
    • Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: Possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis
    • Okada K, Minamino T, Tsukamoto Y, Liao Y, Tsukamoto O, Takashima S et al.Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation 2004;110:705-712.
    • (2004) Circulation , vol.110 , pp. 705-712
    • Okada, K.1    Minamino, T.2    Tsukamoto, Y.3    Liao, Y.4    Tsukamoto, O.5    Takashima, S.6
  • 33
    • 33748789479 scopus 로고    scopus 로고
    • Mediators of endoplasmic reticulum stress-induced apoptosis
    • Szegezdi E, Logue SE, Gorman AM, Samali A. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 2006;7:880-885.
    • (2006) EMBO Rep , vol.7 , pp. 880-885
    • Szegezdi, E.1    Logue, S.E.2    Gorman, A.M.3    Samali, A.4
  • 34
    • 69249132997 scopus 로고    scopus 로고
    • Inhibition of nuclear factor- kB or Bax prevents endoplasmic reticulum stress-but not nitric oxide-mediated apoptosis in INS-1E cells
    • Tonnesen MF, Grunnet LG, Friberg J, Cardozo AK, Billestrup N, Eizirik DL et al.Inhibition of nuclear factor- kB or Bax prevents endoplasmic reticulum stress-but not nitric oxide-mediated apoptosis in INS-1E cells. Endocrinology 2009;150: 4094-4103.
    • (2009) Endocrinology , vol.150 , pp. 4094-4103
    • Tonnesen, M.F.1    Grunnet, L.G.2    Friberg, J.3    Cardozo, A.K.4    Billestrup, N.5    Eizirik, D.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.