메뉴 건너뛰기




Volumn 123, Issue 1, 2013, Pages 46-52

Calcium cycling proteins and heart failure: Mechanisms and therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,5 TETRAHYDRO 7 METHOXY 4 METHYL 1,4 BENZOTHIAZEPINE; 4 [3 (4 BENZYL 1 PIPERIDINYL)PROPIONYL] 2,3,4,5 TETRAHYDRO 7 METHOXY 1,4 BENZOTHIAZEPINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIURETIC AGENT; PHOSPHODIESTERASE INHIBITOR; RYANODINE RECEPTOR 1; RYANODINE RECEPTOR 2; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2A; UNCLASSIFIED DRUG;

EID: 84873880957     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI62834     Document Type: Review
Times cited : (307)

References (65)
  • 1
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3(11):e442.
    • (2006) PLoS Med , vol.3 , Issue.11
    • Mathers, C.D.1    Loncar, D.2
  • 2
    • 80052677303 scopus 로고    scopus 로고
    • Contemporary management and research directions in advanced heart failure: Where are we going?
    • Kamouh A, Francis GS. Kamouh A, Francis GS. Contemporary management and research directions in advanced heart failure: where are we going? Congest Heart Fail. 2011;17(5): 241-247.
    • (2011) Congest Heart Fail. , vol.17 , Issue.5 , pp. 241-247
    • Kamouh, A.1    Francis, G.S.2    Kamouh, A.3    Francis, G.S.4
  • 3
    • 84856135431 scopus 로고    scopus 로고
    • Congestive heart failure: Pathophysiologic consequences of neurohormonal activation and the potential for recovery: Part II
    • Dube P, Weber KT. Congestive heart failure: pathophysiologic consequences of neurohormonal activation and the potential for recovery: part II. Am J Med Sci. 2011;342(6): 503-506.
    • (2011) Am J Med Sci. , vol.342 , Issue.6 , pp. 503-506
    • Dube, P.1    Weber, K.T.2
  • 5
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
    • Marx SO, et al. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell. 2000;101(4): 365-376.
    • (2000) Cell. , vol.101 , Issue.4 , pp. 365-376
    • Marx, S.O.1
  • 6
    • 26244467287 scopus 로고    scopus 로고
    • Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias
    • Lehnart SE, et al. Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias. Cell. 2005;123(1): 25-35.
    • (2005) Cell. , vol.123 , Issue.1 , pp. 25-35
    • Lehnart, S.E.1
  • 7
    • 78649857349 scopus 로고    scopus 로고
    • Role of chronic ryanodine receptor phosphorylation in heart failure and beta-adrenergic receptor blockade in mice
    • Shan J, et al. Role of chronic ryanodine receptor phosphorylation in heart failure and beta-adrenergic receptor blockade in mice. J Clin Invest. 2010; 120(12): 4375-4387.
    • (2010) J Clin Invest. , vol.120 , Issue.12 , pp. 4375-4387
    • Shan, J.1
  • 8
    • 78649324563 scopus 로고    scopus 로고
    • Fixing ryanodine receptor Ca leak - A novel therapeutic strategy for contractile failure in heart and skeletal muscle
    • Andersson DC, Marks AR. Fixing ryanodine receptor Ca leak - a novel therapeutic strategy for contractile failure in heart and skeletal muscle. Drug Discov Today Dis Mech. 2010;7(2):e151-e157.
    • (2010) Drug Discov Today Dis Mech , vol.7 , Issue.2
    • Andersson, D.C.1    Marks, A.R.2
  • 9
    • 45749100010 scopus 로고    scopus 로고
    • Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice
    • Lehnart SE, et al. Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. J Clin Invest. 2008; 118(6): 2230-2245.
    • (2008) J Clin Invest. , vol.118 , Issue.6 , pp. 2230-2245
    • Lehnart, S.E.1
  • 10
    • 33646739318 scopus 로고    scopus 로고
    • Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias
    • Lehnart SE, et al. Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proc Natl Acad Sci U S A. 2006; 103(20): 7906-7910.
    • (2006) Proc Natl Acad Sci U S A. , vol.103 , Issue.20 , pp. 7906-7910
    • Lehnart, S.E.1
  • 11
    • 0027506532 scopus 로고
    • Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium
    • Arai M, Alpert NR, MacLennan DH, Barton P, Periasamy M. Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium. Circ Res. 1993;72(2): 463-469.
    • (1993) Circ Res. , vol.72 , Issue.2 , pp. 463-469
    • Arai, M.1    Alpert, N.R.2    MacLennan, D.H.3    Barton, P.4    Periasamy, M.5
  • 12
    • 0025020589 scopus 로고
    • Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure
    • Morgan JP, Erny RE, Allen PD, Grossman W, Gwathmey JK. Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure. Circulation. 1990; 81(2 suppl):III21-III32.
    • (1990) Circulation , vol.81 , Issue.2 SUPPL.
    • Morgan, J.P.1    Erny, R.E.2    Allen, P.D.3    Grossman, W.4    Gwathmey, J.K.5
  • 13
    • 0037708928 scopus 로고    scopus 로고
    • FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
    • Wehrens XH, et al. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell. 2003;113(7): 829-840.
    • (2003) Cell. , vol.113 , Issue.7 , pp. 829-840
    • Wehrens, X.H.1
  • 14
    • 0035916903 scopus 로고    scopus 로고
    • Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure
    • Hobai IA, O'Rourke B. Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation. 2001;103(11): 1577-1584.
    • (2001) Circulation. , vol.103 , Issue.11 , pp. 1577-1584
    • Hobai, I.A.1    O'Rourke, B.2
  • 15
    • 77957373124 scopus 로고    scopus 로고
    • The ryanodine receptor in cardiac physiology and disease
    • Kushnir A, Marks AR. The ryanodine receptor in cardiac physiology and disease. Adv Pharmacol. 2010;59: 1-30.
    • (2010) Adv Pharmacol. , vol.59 , pp. 1-30
    • Kushnir, A.1    Marks, A.R.2
  • 16
    • 73549115890 scopus 로고    scopus 로고
    • Increased Ca2+) leak and spatiotemporal coherence of Ca2+) release in cardiomyocytes during beta-adrenergic stimulation
    • Ogrodnik J, Niggli E. Increased Ca(2+) leak and spatiotemporal coherence of Ca(2+) release in cardiomyocytes during beta-adrenergic stimulation. J Physiol. 2010;588(pt 1): 225-242.
    • (2010) J Physiol. , vol.588 , Issue.PART 1 , pp. 225-242
    • Ogrodnik, J.1    Niggli, E.2
  • 17
    • 70349973428 scopus 로고    scopus 로고
    • Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart
    • Morimoto S, et al. Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart. Biochem Biophys Res Commun. 2009;390(1): 87-92.
    • (2009) Biochem Biophys Res Commun. , vol.390 , Issue.1 , pp. 87-92
    • Morimoto, S.1
  • 18
    • 72049127316 scopus 로고    scopus 로고
    • A mechanism of ryanodine receptor modulation by FKBP12/12.6, protein kinase A, and K201
    • Blayney LM, Jones JL, Griffiths J, Lai FA. A mechanism of ryanodine receptor modulation by FKBP12/12.6, protein kinase A, and K201. Cardiovasc Res. 2010;85(1): 68-78.
    • (2010) Cardiovasc Res. , vol.85 , Issue.1 , pp. 68-78
    • Blayney, L.M.1    Jones, J.L.2    Griffiths, J.3    Lai, F.A.4
  • 19
    • 0037469180 scopus 로고    scopus 로고
    • FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure
    • Yano M, et al. FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure. Circulation. 2003;107(3): 477-484.
    • (2003) Circulation. , vol.107 , Issue.3 , pp. 477-484
    • Yano, M.1
  • 20
    • 0141571322 scopus 로고    scopus 로고
    • Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes
    • George CH, Higgs GV, Lai FA. Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes. Circ Res. 2003; 93(6): 531-540.
    • (2003) Circ Res. , vol.93 , Issue.6 , pp. 531-540
    • George, C.H.1    Higgs, G.V.2    Lai, F.A.3
  • 21
    • 0034711171 scopus 로고    scopus 로고
    • Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure
    • Yano M, et al. Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure. Circulation. 2000;102(17): 2131-2136.
    • (2000) Circulation. , vol.102 , Issue.17 , pp. 2131-2136
    • Yano, M.1
  • 22
    • 0033770278 scopus 로고    scopus 로고
    • Altered interaction of FKBP12.6 with ryanodine receptor as a cause of abnormal Ca(2+) release in heart failure
    • Ono K, et al. Altered interaction of FKBP12.6 with ryanodine receptor as a cause of abnormal Ca(2+) release in heart failure. Cardiovasc Res. 2000; 48(2): 323-331.
    • (2000) Cardiovasc Res. , vol.48 , Issue.2 , pp. 323-331
    • Ono, K.1
  • 23
    • 0037133555 scopus 로고    scopus 로고
    • Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor
    • Doi M, et al. Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor. Circulation. 2002;105(11): 1374-1379.
    • (2002) Circulation. , vol.105 , Issue.11 , pp. 1374-1379
    • Doi, M.1
  • 24
    • 0029006636 scopus 로고
    • Neurohormonal activation and exercise function in patients with severe heart failure and patients with left ventricular assist system. A comparative study
    • Estrada-Quintero T, Uretsky BF, Murali S, Griffith BP, Kormos RL. Neurohormonal activation and exercise function in patients with severe heart failure and patients with left ventricular assist system. A comparative study. Chest. 1995;107(6): 1499-1503.
    • (1995) Chest. , vol.107 , Issue.6 , pp. 1499-1503
    • Estrada-Quintero, T.1    Uretsky, B.F.2    Murali, S.3    Griffith, B.P.4    Kormos, R.L.5
  • 25
    • 0037414827 scopus 로고    scopus 로고
    • Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol
    • Reiken S, et al. Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol. J Biol Chem. 2003;278(1): 444-453.
    • (2003) J Biol Chem. , vol.278 , Issue.1 , pp. 444-453
    • Reiken, S.1
  • 26
    • 0028358901 scopus 로고
    • Stabilization of calcium release channel (ryanodine receptor) function by FK506- binding protein
    • Brillantes AB, et al. Stabilization of calcium release channel (ryanodine receptor) function by FK506- binding protein. Cell. 1994;77(4): 513-523.
    • (1994) Cell. , vol.77 , Issue.4 , pp. 513-523
    • Brillantes, A.B.1
  • 27
    • 0345268757 scopus 로고    scopus 로고
    • PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: Defective regulation in heart failure
    • Reiken S, et al. PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure. J Cell Biol. 2003;160(6): 919-928.
    • (2003) J Cell Biol. , vol.160 , Issue.6 , pp. 919-928
    • Reiken, S.1
  • 28
    • 22144480949 scopus 로고    scopus 로고
    • Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure
    • Wehrens XH, et al. Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure. Proc Natl Acad Sci U S A. 2005;102(27): 9607-9612.
    • (2005) Proc Natl Acad Sci U S A. , vol.102 , Issue.27 , pp. 9607-9612
    • Wehrens, X.H.1
  • 29
    • 0038662725 scopus 로고    scopus 로고
    • Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure
    • Reiken S, et al. Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure. Circulation. 2003;107(19): 2459-2466.
    • (2003) Circulation. , vol.107 , Issue.19 , pp. 2459-2466
    • Reiken, S.1
  • 30
    • 0035808030 scopus 로고    scopus 로고
    • Beta-adrenergic receptor blockers restore cardiac calcium release channel (ryanodine receptor) structure and function in heart failure
    • Reiken S, et al. beta-adrenergic receptor blockers restore cardiac calcium release channel (ryanodine receptor) structure and function in heart failure. Circulation. 2001;104(23): 2843-2848.
    • (2001) Circulation. , vol.104 , Issue.23 , pp. 2843-2848
    • Reiken, S.1
  • 31
    • 77952670574 scopus 로고    scopus 로고
    • Ryanodine receptor studies using genetically engineered mice
    • Kushnir A, Betzenhauser MJ, Marks AR. Ryanodine receptor studies using genetically engineered mice. FEBS Lett. 2010;584(10): 1956-1965.
    • (2010) FEBS Lett. , vol.584 , Issue.10 , pp. 1956-1965
    • Kushnir, A.1    Betzenhauser, M.J.2    Marks, A.R.3
  • 32
    • 31444432542 scopus 로고    scopus 로고
    • Ryanodine receptor/calcium release channel PKA phosphorylation: A critical mediator of heart failure progression
    • Wehrens XH, Lehnart SE, Reiken S, Vest JA, Wronska A, Marks AR. Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression. Proc Natl Acad Sci U S A. 2006;103(3): 511-518.
    • (2006) Proc Natl Acad Sci U S A. , vol.103 , Issue.3 , pp. 511-518
    • Wehrens, X.H.1    Lehnart, S.E.2    Reiken, S.3    Vest, J.A.4    Wronska, A.5    Marks, A.R.6
  • 33
    • 33644747306 scopus 로고    scopus 로고
    • Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: Rescue of heart failure by calstabin2 in mice
    • Huang F, Shan J, Reiken S, Wehrens XH, Marks AR. Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice. Proc Natl Acad Sci U S A. 2006; 103(9): 3456-3461.
    • (2006) Proc Natl Acad Sci U S A. , vol.103 , Issue.9 , pp. 3456-3461
    • Huang, F.1    Shan, J.2    Reiken, S.3    Wehrens, X.H.4    Marks, A.R.5
  • 34
    • 4444298467 scopus 로고    scopus 로고
    • Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak
    • Lehnart SE, et al. Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak. Circulation. 2004;109(25): 3208-3214.
    • (2004) Circulation. , vol.109 , Issue.25 , pp. 3208-3214
    • Lehnart, S.E.1
  • 35
    • 0030707774 scopus 로고    scopus 로고
    • Inhibition of annexin V-dependent Ca2+ movement in large unilamellar vesicles by K201, a new 1,4-benzothiazepine derivative
    • Kaneko N, Matsuda R, Toda M, Shimamoto K. Inhibition of annexin V-dependent Ca2+ movement in large unilamellar vesicles by K201, a new 1,4-benzothiazepine derivative. Biochim Biophys Acta. 1997;1330(1): 1-7.
    • (1997) Biochim Biophys Acta. , vol.1330 , Issue.1 , pp. 1-7
    • Kaneko, N.1    Matsuda, R.2    Toda, M.3    Shimamoto, K.4
  • 36
    • 0034082466 scopus 로고    scopus 로고
    • JTV-519, a novel cardioprotective agent, improves the contractile recovery after ischaemia-reperfusion in coronary perfused guinea-pig ventricular muscles
    • Ito K, Shigematsu S, Sato T, Abe T, Li Y, Arita M. JTV-519, a novel cardioprotective agent, improves the contractile recovery after ischaemia-reperfusion in coronary perfused guinea-pig ventricular muscles. Br J Pharmacol. 2000;130(4): 767-776.
    • (2000) Br J Pharmacol. , vol.130 , Issue.4 , pp. 767-776
    • Ito, K.1    Shigematsu, S.2    Sato, T.3    Abe, T.4    Li, Y.5    Arita, M.6
  • 37
    • 0034119434 scopus 로고    scopus 로고
    • Effects of JTV-519, a novel anti-ischaemic drug, on the delayed rectifier K+ current in guinea-pig ventricular myocytes
    • Kiriyama K, Kiyosue T, Wang JC, Dohi K, Arita M. Effects of JTV-519, a novel anti-ischaemic drug, on the delayed rectifier K+ current in guinea-pig ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol. 2000;361(6): 646-653.
    • (2000) Naunyn Schmiedebergs Arch Pharmacol. , vol.361 , Issue.6 , pp. 646-653
    • Kiriyama, K.1    Kiyosue, T.2    Wang, J.C.3    Dohi, K.4    Arita, M.5
  • 38
    • 0032925839 scopus 로고    scopus 로고
    • Effects of a novel cardioprotective drug, JTV- 519, on membrane currents of guinea pig ventricular myocytes
    • Kimura J, Kawahara M, Sakai E, Yatabe J, Nakanishi H. Effects of a novel cardioprotective drug, JTV- 519, on membrane currents of guinea pig ventricular myocytes. Jpn J Pharmacol. 1999;79(3): 275-281.
    • (1999) Jpn J Pharmacol. , vol.79 , Issue.3 , pp. 275-281
    • Kimura, J.1    Kawahara, M.2    Sakai, E.3    Yatabe, J.4    Nakanishi, H.5
  • 39
    • 1842482414 scopus 로고    scopus 로고
    • Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2
    • Wehrens XH, et al. Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2. Science. 2004;304(5668): 292-296.
    • (2004) Science. , vol.304 , Issue.5668 , pp. 292-296
    • Wehrens, X.H.1
  • 40
    • 80051960845 scopus 로고    scopus 로고
    • Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion
    • Fauconnier J, et al. Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion. Proc Natl Acad Sci U S A. 2011;108(32): 13258-13263.
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , Issue.32 , pp. 13258-13263
    • Fauconnier, J.1
  • 41
    • 79960940824 scopus 로고    scopus 로고
    • Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
    • Andersson DC, et al. Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging. Cell Metab. 2011;14(2): 196-207.
    • (2011) Cell Metab. , vol.14 , Issue.2 , pp. 196-207
    • Andersson, D.C.1
  • 42
    • 76549098001 scopus 로고    scopus 로고
    • Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy
    • Fauconnier J, et al. Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2010;107(4): 1559-1564.
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , Issue.4 , pp. 1559-1564
    • Fauconnier, J.1
  • 43
    • 61949338001 scopus 로고    scopus 로고
    • Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle
    • Bellinger AM, et al. Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle. Nat Med. 2009;15(3): 325-330.
    • (2009) Nat Med. , vol.15 , Issue.3 , pp. 325-330
    • Bellinger, A.M.1
  • 44
    • 78649835004 scopus 로고    scopus 로고
    • Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice
    • Shan J, et al. Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice. J Clin Invest. 2010;120(12): 4388-4398.
    • (2010) J Clin Invest. , vol.120 , Issue.12 , pp. 4388-4398
    • Shan, J.1
  • 45
    • 78649712955 scopus 로고    scopus 로고
    • Dantrolene, a therapeutic agent for malignant hyperthermia, inhibits catecholaminergic polymorphic ventricular tachycardia in a RyR2(R2474S/+) knock-in mouse model
    • Kobayashi S, et al. Dantrolene, a therapeutic agent for malignant hyperthermia, inhibits catecholaminergic polymorphic ventricular tachycardia in a RyR2(R2474S/+) knock-in mouse model. Circ J. 2010;74(12): 2579-2584.
    • (2010) Circ J. , vol.74 , Issue.12 , pp. 2579-2584
    • Kobayashi, S.1
  • 46
    • 79957553666 scopus 로고    scopus 로고
    • Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia
    • van der Werf C, et al. Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia. J Am Coll Cardiol. 2011; 57(22): 2244-2254.
    • (2011) J Am Coll Cardiol. , vol.57 , Issue.22 , pp. 2244-2254
    • Van Der Werf, C.1
  • 47
  • 48
    • 10744230243 scopus 로고    scopus 로고
    • Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity
    • Schultz Jel J, et al. Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity. Am J Physiol Heart Circ Physiol. 2004;286(3):H1146-H1153.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286 , Issue.3
    • Schultz Jel, J.1
  • 49
    • 4544365484 scopus 로고    scopus 로고
    • Expression of the sarco/endoplasmic reticulum calcium ATPase type 2 and 3 isoforms in normal skin and Darier's disease
    • Tavadia S, Authi KS, Hodgins MB, Munro CS. Expression of the sarco/endoplasmic reticulum calcium ATPase type 2 and 3 isoforms in normal skin and Darier's disease. Br J Dermatol. 2004; 151(2): 440-445.
    • (2004) Br J Dermatol. , vol.151 , Issue.2 , pp. 440-445
    • Tavadia, S.1    Authi, K.S.2    Hodgins, M.B.3    Munro, C.S.4
  • 50
    • 85047687537 scopus 로고    scopus 로고
    • Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human
    • Haghighi K, et al. Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human. J Clin Invest. 2003;111(6): 869-876.
    • (2003) J Clin Invest. , vol.111 , Issue.6 , pp. 869-876
    • Haghighi, K.1
  • 51
    • 0032576586 scopus 로고    scopus 로고
    • Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts
    • Baker DL, et al. Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts. Circ Res. 1998;83(12): 1205-1214.
    • (1998) Circ Res. , vol.83 , Issue.12 , pp. 1205-1214
    • Baker, D.L.1
  • 52
    • 11144353634 scopus 로고    scopus 로고
    • Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+- ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias
    • Chen Y, et al. Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+- ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias. Circulation. 2004;109(15): 1898-1903.
    • (2004) Circulation. , vol.109 , Issue.15 , pp. 1898-1903
    • Chen, Y.1
  • 53
    • 1842732159 scopus 로고    scopus 로고
    • Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling
    • del Monte F, et al. Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling. Proc Natl Acad Sci U S A. 2004;101(15): 5622-5627.
    • (2004) Proc Natl Acad Sci U S A. , vol.101 , Issue.15 , pp. 5622-5627
    • Del Monte, F.1
  • 54
    • 79961032369 scopus 로고    scopus 로고
    • Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (cupid): A phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum ca2+- atpase in patients with advanced heart failure
    • Jessup M, et al. Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+- ATPase in patients with advanced heart failure. Circulation. 2011;124(3): 304-313.
    • (2011) Circulation. , vol.124 , Issue.3 , pp. 304-313
    • Jessup, M.1
  • 55
    • 0037372101 scopus 로고    scopus 로고
    • A new cardioprotective agent, JTV519, improves defective channel gating of ryanodine receptor in heart failure
    • Kohno M, et al. A new cardioprotective agent, JTV519, improves defective channel gating of ryanodine receptor in heart failure. Am J Physiol Heart Circ Physiol. 2003;284(3):H1035-H1042.
    • (2003) Am J Physiol Heart Circ Physiol. , vol.284 , Issue.3
    • Kohno, M.1
  • 56
    • 0035941418 scopus 로고    scopus 로고
    • Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a
    • Antos CL, et al. Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a. Circ Res. 2001;89(11): 997-1004.
    • (2001) Circ Res. , vol.89 , Issue.11 , pp. 997-1004
    • Antos, C.L.1
  • 57
    • 0042707870 scopus 로고    scopus 로고
    • Dysregulated ryanodine receptors mediate cellular toxicity: Restoration of normal phenotype by FKBP12.6
    • George CH, Higgs GV, Mackrill JJ, Lai FA. Dysregulated ryanodine receptors mediate cellular toxicity: restoration of normal phenotype by FKBP12.6. J Biol Chem. 2003;278(31): 28856-28864.
    • (2003) J Biol Chem. , vol.278 , Issue.31 , pp. 28856-28864
    • George, C.H.1    Higgs, G.V.2    MacKrill, J.J.3    Lai, F.A.4
  • 58
    • 84858652117 scopus 로고    scopus 로고
    • Ryanodine receptor s2808 phosphorylation in heart failure: Smoking gun or red herring
    • Bers DM. Ryanodine receptor s2808 phosphorylation in heart failure: smoking gun or red herring. Circ Res. 2012;110(6): 796-799.
    • (2012) Circ Res. , vol.110 , Issue.6 , pp. 796-799
    • Bers, D.M.1
  • 59
    • 0037465735 scopus 로고    scopus 로고
    • A guide for the perplexed: Towards an understanding of the molecular basis of heart failure
    • Marks AR. A guide for the perplexed: towards an understanding of the molecular basis of heart failure. Circulation. 2003;107(11): 1456-1459.
    • (2003) Circulation. , vol.107 , Issue.11 , pp. 1456-1459
    • Marks, A.R.1
  • 60
    • 0029810883 scopus 로고    scopus 로고
    • Selective binding of FKBP12.6 by the cardiac ryanodine receptor
    • Timerman AP, et al. Selective binding of FKBP12.6 by the cardiac ryanodine receptor. J Biol Chem. 1996; 271(34): 20385-20391.
    • (1996) J Biol Chem. , vol.271 , Issue.34 , pp. 20385-20391
    • Timerman, A.P.1
  • 61
    • 0028206051 scopus 로고
    • The ryanodine receptor from canine heart sarcoplasmic reticulum is associated with a novel FK-506 binding protein
    • Timerman AP, Jayaraman T, Wiederrecht G, Onoue H, Marks AR, Fleischer S. The ryanodine receptor from canine heart sarcoplasmic reticulum is associated with a novel FK-506 binding protein. Biochem Biophys Res Commun. 1994;198(2): 701-706.
    • (1994) Biochem Biophys Res Commun. , vol.198 , Issue.2 , pp. 701-706
    • Timerman, A.P.1    Jayaraman, T.2    Wiederrecht, G.3    Onoue, H.4    Marks, A.R.5    Fleischer, S.6
  • 62
    • 0031974445 scopus 로고    scopus 로고
    • Differentiation-dependent expression of cardiac delta-CaMKII isoforms
    • Hoch B, et al. Differentiation-dependent expression of cardiac delta-CaMKII isoforms. J Cell Biochem. 1998;68(2): 259-268.
    • (1998) J Cell Biochem. , vol.68 , Issue.2 , pp. 259-268
    • Hoch, B.1
  • 63
    • 66449097490 scopus 로고    scopus 로고
    • Requirement for Ca2+/calmodulindependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice
    • Ling H, et al. Requirement for Ca2+/calmodulindependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest. 2009;119(5): 1230-1240.
    • (2009) J Clin Invest. , vol.119 , Issue.5 , pp. 1230-1240
    • Ling, H.1
  • 64
    • 84861591191 scopus 로고    scopus 로고
    • Role of RyR2 phosphorylation at S2814 during heart failure progression
    • Respress JL, et al. Role of RyR2 phosphorylation at S2814 during heart failure progression. Circ Res. 2012;110(11): 1474-1483.
    • (2012) Circ Res. , vol.110 , Issue.11 , pp. 1474-1483
    • Respress, J.L.1
  • 65
    • 77953418093 scopus 로고    scopus 로고
    • Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure
    • Kushnir A, Shan J, Betzenhauser MJ, Reiken S, Marks AR. Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure. Proc Natl Acad Sci U S A. 2010;107(22): 10274-10279.
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , Issue.22 , pp. 10274-10279
    • Kushnir, A.1    Shan, J.2    Betzenhauser, M.J.3    Reiken, S.4    Marks, A.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.