Calpain-mediated dystrophin disruption may be a potential structural culprit behind chronic doxorubicin-induced cardiomyopathy

European Journal of Pharmacology

Volumn 670, Issue 2-3, 2011, Pages 541-553

  Campos, Erica C ^a   O'Connell, João L ^a   Malvestio, Lygia M ^a   Romano, Minna M Dias ^a   Ramos, Simone G ^a   Celes, Mara Rúbia N ^a   Prado, Cibele M ^a   Simões, Marcus V ^a   Rossi, Marcos A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Anthracyclines; Cancer; Cardiomyopathy; Doxorubicin; Dystrophin; Heart failure

Indexed keywords

ACTIN; CALPAIN; DANTROLENE; DOXORUBICIN; DYSTROPHIN; GLYCOPROTEIN; MYOSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CARDIOTOXICITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG POTENTIATION; HEART FUNCTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE; MALE; MEMBRANE PERMEABILITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SURVIVAL RATE;

ACTINS; ANIMALS; BODY WEIGHT; CALPAIN; CARDIOMYOPATHIES; CELL MEMBRANE PERMEABILITY; DANTROLENE; DOXORUBICIN; DYSTROPHIN; ELECTROCARDIOGRAPHY; HEART; LUNG; MALE; MYOCARDIUM; MYOSINS; ORGAN SIZE; RATS; RATS, WISTAR; SARCOLEMMA; SURVIVAL ANALYSIS; TIME FACTORS;

EID: 80755132135     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.09.021     Document Type: Article

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