Differential sensitivity to LPS-induced myocardial dysfunction in the isolated brown Norway and DAHL S rat hearts: Roles of mitochondrial function, NF-κB activation, and TNF-α production

Shock

Volumn 37, Issue 3, 2012, Pages 325-332

  An, Jianzhong ^a,b,c   Du, Jianhai ^a,b,c   Wei, Na ^a,b,d   Guan, Tongju ^a,b,c   Camara, Amadou K S ^a,c   Shi, Yang ^a,b,c  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b Children's Research Institute   (China)

^c Cardiovascular Research Center   (China)

^d SHANDONG UNIVERSITY   (China)

Author keywords

Brown Norway rats; Dahl S rats; lipopolysaccharide; mitochondria; Myocardial dysfunction; NF B pathway; proinflammatory cytokines

Indexed keywords

ENDOTOXIN; HYDROGEN PEROXIDE; I KAPPA B; I KAPPA B KINASE BETA; LIPOPOLYSACCHARIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; BROWN NORWAY RAT; CELL FUNCTION; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; EX VIVO STUDY; HEART CONTRACTION; HEART FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE OXYGEN CONSUMPTION; HEART MUSCLE RELAXATION; HEART PERFUSION; IN VIVO STUDY; ISOLATED HEART; MALE; MITOCHONDRION; MYOCARDIAL DISEASE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; HEART; HEART FAILURE; HYDROGEN PEROXIDE; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MITOCHONDRIA, HEART; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIAL CONTRACTION; MYOCARDIUM; NF-KAPPA B; OXYGEN CONSUMPTION; PERFUSION; RATS; RATS, INBRED BN; RATS, INBRED DAHL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84857540652     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31823f146f     Document Type: Article

References (35)

1. Heron M: Deaths: leading causes for 2004. Natl Vital Stat Rep 56(5):1-95, 2007.
2. Flierl MA, Rittirsch D, Huber-Lang MS, Sarma JV, Ward PA: Molecular events in the cardiomyopathy of sepsis. Mol Med 14(5-6):327-336, 2008. (Pubitemid 351785706)
3. Corda S, Laplace C, Vicaut E, Duranteau J: Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factoralpha is mediated by ceramide. Am J Respir Cell Mol Biol 24(6):762-768, 2001. (Pubitemid 32550600)
4. Levy RJ: Mitochondrial dysfunction, bioenergetic impairment, and metabolic downregulation in sepsis. Shock 28(1):24-28, 2007. (Pubitemid 46956458)
5. Trumbeckaite S, Opalka JR, Neuhof C, Zierz S, Gellerich FN: Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function. Eur J Biochem 268(5):1422-1429, 2001. (Pubitemid 32231896)
6. Taylor DE, Ghio AJ, Piantadosi CA: Reactive oxygen species produced by liver mitochondria of rats in sepsis. Arch Biochem Biophys 316(1):70-76, 1995.
7. An J, Du J, Wei N, Xu H, Pritchard KA Jr, Shi Y: Role of tetrahydrobiopterin in resistance to myocardial ischemia in Brown Norway and Dahl S rats. Am J Physiol Heart Circ Physiol 297(5):H1783YH1791, 2009.
8. Cowley AW Jr, Roman RJ, Kaldunski ML, Dumas P, Dickhout JG, Greene AS, Jacob HJ: Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. Hypertension 37(2 Pt 2):456-461, 2001. (Pubitemid 32199011)
9. Drenjancevic-Peric I, Phillips SA, Falck JR, Lombard JH: Restoration of normal vascular relaxation mechanisms in cerebral arteries by chromosomal substitution in consomic SS.13BN rats. Am J Physiol Heart Circ Physiol 289(1): H188YH195, 2005. (Pubitemid 40934098)
10. Shi Y, Hutchins W, Ogawa H, Chang CC, Pritchard KA Jr, Zhang C, Khampang P, Lazar J, Jacob HJ, Rafiee P, et al.: Increased resistance to myocardial ischemia in the Brown Norway vs. Dahl S rat: role of nitric oxide synthase and Hsp90. J Mol Cell Cardiol 38(4):625-635, 2005. (Pubitemid 40461826)
11. Du J, An J, Wei N, Guan T, Pritchard KA Jr, Shi Y: Increased resistance to LPS-induced myocardial dysfunction in the Brown Norway rats versus Dahl S rats: roles of inflammatory cytokines and nuclear factor kappaB pathway. Shock 33(3):332-336, 2010.
12. Aldakkak M, Stowe DF, Cheng Q, Kwok WM, Camara AK: Mitochondrial matrix K+ flux independent of large-conductance Ca2+-activated K+ channel opening. Am J Physiol Cell Physiol 298(3):C530YC541, 2010.
13. Haumann J, Dash RK, Stowe DF, Boelens AD, Beard DA, Camara AK: Mitochondrial free [Ca2+] increases during ATP/ADP antiport and ADP phosphorylation: exploration of mechanisms. Biophys J 99(4):997-1006, 2010.
14. Janssen AJ, Trijbels FJ, Sengers RC, Smeitink JA, van den Heuvel LP, Wintjes LT, Stoltenborg-Hogenkamp BJ, Rodenburg RJ: Spectrophotometric assay for complex I of the respiratory chain in tissue samples and cultured fibroblasts. Clin Chem 53(4):729-734, 2007. (Pubitemid 46580245)
15. Peng T, Zhang T, Lu X, Feng Q: JNK1/c-fos inhibits cardiomyocyte TNF-alpha expression via a negative crosstalk with ERK and p38 MAPK in endotoxaemia. Cardiovasc Res 81(4):733-741, 2009.
16. Huet O, Dupic L, Harrois A, Duranteau J: Oxidative stress and endothelial dysfunction during sepsis. Front Biosci 16(0):1986-1995, 2011.
17. Ding J, Song D, Ye X, Liu SF: A pivotal role of endothelial-specific NF-kappaB signaling in the pathogenesis of septic shock and septic vascular dysfunction. J Immunol 183(6):4031-4038, 2009.
18. Grandel U, Fink L, Blum A, Heep M, Buerke M, Kraemer HJ, Mayer K, Bohle RM, Seeger W, Grimminger F, et al.: Endotoxin-induced myocardial tumor necrosis factor-alpha synthesis depresses contractility of isolated rat hearts: evidence for a role of sphingosine and cyclooxygenase-2Yderived thromboxane production. Circulation 102(22):2758-2764, 2000.
19. Davies NA, Cooper CE, Stidwill R, Singer M: Inhibition of mitochondrial respiration during early stage sepsis. Adv Exp Med Biol 530(0):725-736, 2003. (Pubitemid 37352415)
20. Vanasco V, Cimolai MC, Evelson P, Alvarez S: The oxidative stress and the mitochondrial dysfunction caused by endotoxemia are prevented by alphalipoic acid. Free Radic Res 42(9):815-823, 2008.
21. Dirami G, Massaro D, Clerch LB: Regulation of lung manganese superoxide dismutase: species variation in response to lipopolysaccharide. Am J Physiol 276(5 Pt 1):L705YL708, 1999. (Pubitemid 29249622)
22. Suliman HB, Welty-Wolf KE, Carraway M, Tatro L, Piantadosi CA: Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis. Cardiovasc Res 64(2):279-288, 2004. (Pubitemid 39361689)
23. Brookes PS: Mitochondrial H(+) leak and ROS generation: an odd couple. Free Radic Biol Med 38(1):12-23, 2005. (Pubitemid 39626904)
24. Stowe DF, Camara AK: Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function. Antioxid Redox Signal 11(6):1373-1414, 2009.
25. Crouser ED: Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome. Mitochondrion 4(5-6):729-741, 2004. (Pubitemid 39646818)
26. Liu J, Wu F, Liu Y, Zhang T, Tang Z: The effect of melatonin on mitochondrial function in endotoxemia induced by lipopolysaccharide. Asian Aust J Anim Sci 24(6):10, 2011.
27. Kozlov AV, Staniek K, Haindl S, Piskernik C, Ohlinger W, Gille L, Nohl H, Bahrami S, Redl H: Different effects of endotoxic shock on the respiratory function of liver and heart mitochondria in rats. Am J Physiol Gastrointest Liver Physiol 290(3):G543YG549, 2006.
28. Singer M, De Santis V, Vitale D, Jeffcoate W: Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation. Lancet 364(9433):545-548, 2004. (Pubitemid 39070417)
29. Suliman HB, Carraway MS, Piantadosi CA: Postlipopolysaccharide oxidative damage of mitochondrial DNA. Am J Respir Crit Care Med 167(4):570-579, 2003.
30. Suliman HB, Babiker A, Withers CM, Sweeney TE, Carraway MS, Tatro LG, Bartz RR, Welty-Wolf KE, Piantadosi CA: Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice. Free Radic Biol Med 48(5):736-746, 2010.
31. Wagner DR, Combes A, McTiernan C, Sanders VJ, Lemster B, Feldman AM: Adenosine inhibits lipopolysaccharide-induced cardiac expression of tumor necrosis factor-alpha. Circ Res 82(1):47-56, 1998. (Pubitemid 28074018)
32. Yokoyama T, Sekiguchi K, Tanaka T, Tomaru K, Arai M, Suzuki T, Nagai R: Angiotensin II and mechanical stretch induce production of tumor necrosis factor in cardiac fibroblasts. Am J Physiol 276(6 Pt 2):H1968YH1976, 1999. (Pubitemid 29323481)
33. Peng T, Lu X, Feng Q: Pivotal role of gp91phox-containing NADH oxidase in lipopolysaccharide-induced tumor necrosis factor-alpha expression and myocardial depression. Circulation 111(13):1637-1644, 2005. (Pubitemid 40525163)
34. Remick DG, Newcomb DE, Bolgos GL, Call DR: Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture. Shock 13(2):110-116, 2000.
35. Waage A, Halstensen A, Espevik T: Association between tumor necrosis factor in serum and fatal outcome in patients with meningococcal disease. Lancet 1(8529):355-357, 1987. (Pubitemid 17010024)