Fasudil hydrochloride hydrate, a rho-kinase inhibitor, suppresses isoproterenol-induced heart failure in rats via JNK and ERK1/2 pathways

Journal of Cellular Biochemistry

Volumn 112, Issue 7, 2011, Pages 1920-1929

  Wang, Na ^a   Guan, Peng ^b   Zhang, Jian Ping ^a   Li, Ya Qing ^b   Chang, Yan Zhong ^b   Shi, Zhen Hua ^b   Wang, Feng Yun ^a   Chu, Li ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI NORMAL UNIVERSITY   (China)

Author keywords

Fasudil; Heart failure; Isoproterenol; Rho Kinaes

Indexed keywords

FASUDIL; FLICE INHIBITORY PROTEIN; ISOPRENALINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MYOSIN I; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; BIOMETRY; CONTROLLED STUDY; DIET; DRUG MEGADOSE; GENE EXPRESSION; HEART FAILURE; HEMODYNAMICS; HISTOLOGY; LOW DRUG DOSE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SPRAGUE DAWLEY RAT; UPREGULATION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; ENZYME ACTIVATION; GENE EXPRESSION; HEART; HEART FAILURE; HEMODYNAMICS; ISOPROTERENOL; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 8; MYOCARDIUM; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES;

RATTUS;

EID: 80051485388     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23112     Document Type: Article

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