Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 29, 2012, Pages 11794-11799

  Maier, Harald J ^a   Schips, Tobias G ^a,d   Wietelmann, Astrid ^b   Krüger, Marcus ^b   Brunner, Cornelia ^a   Sauter, Martina ^c   Klingel, Karin ^c   Böttger, Thomas ^b   Braun, Thomas ^b   Wirth, Thomas ^a  

^a UNIVERSITY OF ULM   (Germany)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Transcription factors; Transgenic mice

Indexed keywords

CD11B ANTIGEN; CYTOKINE; I KAPPA B ALPHA; I KAPPA B KINASE; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; PROTEIN; PROTEIN ISG15; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROSIS; GENE EXPRESSION; HEART FAILURE; HEART MUSCLE CELL; IN VIVO STUDY; INFLAMMATION; MOLECULAR PATHOLOGY; MOUSE; MUSCLE ATROPHY; MUSCLE HYPERTROPHY; MYOCARDITIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; TRANSGENIC MOUSE;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD11B; BLOTTING, WESTERN; CARDIOMYOPATHIES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; HEART FAILURE; HISTOLOGICAL TECHNIQUES; I-KAPPA B KINASE; I-KAPPA B PROTEINS; LUMINESCENT MEASUREMENTS; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MYOCYTES, CARDIAC; NF-KAPPA B;

ANIMALIA; COXSACKIEVIRUS; MUS MUSCULUS;

EID: 84863946664     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1116584109     Document Type: Article

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