Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-B signaling pathway

Acta Pharmacologica Sinica

Volumn 33, Issue 5, 2012, Pages 668-674

  Huang, Wei ^a   Shang, Wei Lin ^a   Wang, Hua Dong ^a   Wu, Wen Wen ^a   Hou, Shu Xun ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Alkaline phosphatase; EX 527; NF B; NO; Osteoblast; Osteocalcin; Resveratrol; Runt related transcription factor 2 (Runx2); Sirt1; TNF

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; RESVERATROL; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA;

ADENOVIRUS; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; IN VITRO STUDY; MOUSE; NONHUMAN; OSTEOBLAST; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARBAZOLES; CELL LINE, TUMOR; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CYTOPROTECTION; ENZYME ACTIVATION; ENZYME ACTIVATORS; HISTONE DEACETYLASE INHIBITORS; INFLAMMATION MEDIATORS; MICE; NF-KAPPA B; NITRIC OXIDE; OSTEOBLASTS; OSTEOCALCIN; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SIRTUIN 1; STILBENES; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84860759272     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.189     Document Type: Article

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