메뉴 건너뛰기




Volumn 8, Issue 1, 2010, Pages 64-74

Hyperhomocysteinemia and sudden cardiac death: Potential arrhythmogenic mechanisms

Author keywords

Arrhythmia; Atrioventricular node; Connexins; Electrophysiology; Glutamate receptors; Homocysteine; Hyperhomocysteinemia; Sudden cardiac death

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; FIBRIC ACID DERIVATIVE; GAP JUNCTION PROTEIN; HOMOCYSTEINE; HYDROGEN SULFIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MATRIX METALLOPROTEINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; ROSUVASTATIN; VITAMIN B GROUP;

EID: 77949497887     PISSN: 15701611     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016110790226552     Document Type: Review
Times cited : (22)

References (108)
  • 1
    • 0036848968 scopus 로고    scopus 로고
    • Increased serum homocysteine and sudden death resulting from coronary atherosclerosis with fibrous plaques
    • Burke AP, Fonseca V, Kolodgie F, Zieske A, Fink L, Virmani R. Increased serum homocysteine and sudden death resulting from coronary atherosclerosis with fibrous plaques. Arterioscler Thromb Vasc Biol 2002; 22: 1936-41.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1936-1941
    • Burke, A.P.1    Fonseca, V.2    Kolodgie, F.3    Zieske, A.4    Fink, L.5    Virmani, R.6
  • 2
    • 0036088319 scopus 로고    scopus 로고
    • Paradoxical overexpression and translocation of connexin43 in homocysteine-treated endothelial cells
    • Li H, Brodsky S, Kumari S, Valiunas V, Brink P, Kaide J, et al. Paradoxical overexpression and translocation of connexin43 in homocysteine-treated endothelial cells. Am J Physiol Heart Circ Physiol 2002; 282: H2124-33.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Li, H.1    Brodsky, S.2    Kumari, S.3    Valiunas, V.4    Brink, P.5    Kaide, J.6
  • 4
    • 0032602518 scopus 로고    scopus 로고
    • A hyperhomocysteinemia study in a population with a familial factor for acute myocardial infarct and sudden cardiac death at a young age
    • Bollani G, Ferrari R, Bersatti F, Ferrari M, Cattaneo M, Zighetti ML, et al. A hyperhomocysteinemia study in a population with a familial factor for acute myocardial infarct and sudden cardiac death at a young age. Cardiologia 1999; 44: 75-81.
    • (1999) Cardiologia , vol.44 , pp. 75-81
    • Bollani, G.1    Ferrari, R.2    Bersatti, F.3    Ferrari, M.4    Cattaneo, M.5    Zighetti, M.L.6
  • 6
    • 0029806746 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
    • Ma J, Stampfer MJ, Hennekens CH, Frosst P, Selhub J, Horsford J, et al. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 1997; 94: 2410-6.
    • (1997) Circulation , vol.94 , pp. 2410-2416
    • Ma, J.1    Stampfer, M.J.2    Hennekens, C.H.3    Frosst, P.4    Selhub, J.5    Horsford, J.6
  • 7
    • 0012564822 scopus 로고    scopus 로고
    • Methionine and homocysteine metabolism and the nutritional prevention of certain birth defects and complications of pregnancy
    • Miller AL, Kelly GS. Methionine and homocysteine metabolism and the nutritional prevention of certain birth defects and complications of pregnancy. Altern Med Rev 1996; 1: 220-35.
    • (1996) Altern Med Rev , vol.1 , pp. 220-235
    • Miller, A.L.1    Kelly, G.S.2
  • 8
    • 0028845307 scopus 로고
    • Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men
    • Perry IJ, Refsum H, Morris RW, Ebrahim SB, Ueland PM, Shaper AG. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 1995; 346: 1395-8.
    • (1995) Lancet , vol.346 , pp. 1395-1398
    • Perry, I.J.1    Refsum, H.2    Morris, R.W.3    Ebrahim, S.B.4    Ueland, P.M.5    Shaper, A.G.6
  • 11
    • 27744574967 scopus 로고    scopus 로고
    • Epidemiology and stratification of risk for sudden cardiac death
    • Podrid PJ, Myerburg RJ. Epidemiology and stratification of risk for sudden cardiac death. Clin Cardiol 2005; 28 (11 Suppl.): I3-11.
    • (2005) Clin Cardiol , vol.28 , Issue.11 SUPPL.
    • Podrid, P.J.1    Myerburg, R.J.2
  • 12
    • 0036182632 scopus 로고    scopus 로고
    • Reversal of endocardial endothelial dysfunction by folic acid in homocysteinemic hypertensive rats
    • Miller A, Mujumdar V, Palmer L, Bower JD, Tyagi SC. Reversal of endocardial endothelial dysfunction by folic acid in homocysteinemic hypertensive rats. Am J Hypertens 2002; 15: 157-63.
    • (2002) Am J Hypertens , vol.15 , pp. 157-163
    • Miller, A.1    Mujumdar, V.2    Palmer, L.3    Bower, J.D.4    Tyagi, S.C.5
  • 13
    • 21044433581 scopus 로고    scopus 로고
    • Identification of a homocysteine receptor in the peripheral endothelium and its role in proliferation
    • Chen H, Fitzgerald R, Brown AT, Qureshi I, Breckenridge J, Kazi R, et al. Identification of a homocysteine receptor in the peripheral endothelium and its role in proliferation. J Vasc Surg 2005; 41: 853-60.
    • (2005) J Vasc Surg , vol.41 , pp. 853-860
    • Chen, H.1    Fitzgerald, R.2    Brown, A.T.3    Qureshi, I.4    Breckenridge, J.5    Kazi, R.6
  • 14
  • 15
    • 58649087623 scopus 로고    scopus 로고
    • Nitrotyrosinylation, remodeling and endothelial-myocyte uncoupling in iNOS, cystathionine beta synthase (CBS) knockouts and iNOS/CBS double knockout mice
    • Kundu S, Kumar M, Sen U, Mishra PK, Tyagi N, Metreveli N, et al. Nitrotyrosinylation, remodeling and endothelial-myocyte uncoupling in iNOS, cystathionine beta synthase (CBS) knockouts and iNOS/CBS double knockout mice. J Cell Biochem 2009; 106: 119-26.
    • (2009) J Cell Biochem , vol.106 , pp. 119-126
    • Kundu, S.1    Kumar, M.2    Sen, U.3    Mishra, P.K.4    Tyagi, N.5    Metreveli, N.6
  • 16
    • 0036196099 scopus 로고    scopus 로고
    • Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
    • Mungrue IN, Gros R, You X. Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. J Clin Invest 2002; 109: 735-43.
    • (2002) J Clin Invest , vol.109 , pp. 735-743
    • Mungrue, I.N.1    Gros, R.2    You, X.3
  • 17
    • 0032527491 scopus 로고    scopus 로고
    • Molecular and immunochemical characterization of the ionotropic glutamate receptors in the rat heart
    • Gill SS, Pulido OM, Mueller RW, McGuire PF. Molecular and immunochemical characterization of the ionotropic glutamate receptors in the rat heart. Brain Res Bull 1998; 46: 429-34.
    • (1998) Brain Res Bull , vol.46 , pp. 429-434
    • Gill, S.S.1    Pulido, O.M.2    Mueller, R.W.3    McGuire, P.F.4
  • 18
    • 33845421205 scopus 로고    scopus 로고
    • Homocysteine-mediated activation and mitochondrial translocation of calpain regulates MMP-9 in MVEC
    • Moshal KS, Singh M, Sen U. Homocysteine-mediated activation and mitochondrial translocation of calpain regulates MMP-9 in MVEC. Am J Physiol Heart Circ Physiol 2006; 291: H2825-35.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Moshal, K.S.1    Singh, M.2    Sen, U.3
  • 19
    • 0037350326 scopus 로고    scopus 로고
    • The monkey (Macaca fascicularis) heart neural structures and conducting system: An immunochemical study of selected neural biomarkers and glutamate receptors
    • Mueller RW, Gill SS, Pulido OM. The monkey (Macaca fascicularis) heart neural structures and conducting system: an immunochemical study of selected neural biomarkers and glutamate receptors. Toxicol Pathol 2003; 31: 227-34.
    • (2003) Toxicol Pathol , vol.31 , pp. 227-234
    • Mueller, R.W.1    Gill, S.S.2    Pulido, O.M.3
  • 20
    • 36849000444 scopus 로고    scopus 로고
    • NMDA receptor activation induces mitochondrial dysfunction, oxidative stress and apoptosis in cultured neonatal rat cardiomyocytes
    • Gao X, Xu X, Pang J, Zhang C, Ding JM, Peng X, et al. NMDA receptor activation induces mitochondrial dysfunction, oxidative stress and apoptosis in cultured neonatal rat cardiomyocytes. Physiol Res 2007; 56: 559-69.
    • (2007) Physiol Res , vol.56 , pp. 559-569
    • Gao, X.1    Xu, X.2    Pang, J.3    Zhang, C.4    Ding, J.M.5    Peng, X.6
  • 21
    • 34347335713 scopus 로고    scopus 로고
    • Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease
    • Boldyrev AA, Johnson P. Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease. J Alzheimers Dis 2007; 11: 219-28.
    • (2007) J Alzheimers Dis , vol.11 , pp. 219-228
    • Boldyrev, A.A.1    Johnson, P.2
  • 23
    • 33947399870 scopus 로고    scopus 로고
    • Human heart glutamate receptors - implications for toxicology, food safety and drug discovery
    • Gill S, Veinot J, Kavanagh M, Pulido O. Human heart glutamate receptors - implications for toxicology, food safety and drug discovery. Toxicol Pathol 2007; 35: 411-7.
    • (2007) Toxicol Pathol , vol.35 , pp. 411-417
    • Gill, S.1    Veinot, J.2    Kavanagh, M.3    Pulido, O.4
  • 24
    • 0030915272 scopus 로고    scopus 로고
    • Lipton SA, Kim WK, Choi YB, Kumar S, D 'Emilia DM, Rayudu PV, et al. Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proc Natl Acad Sci USA 1997; 94: 5923-8.
    • Lipton SA, Kim WK, Choi YB, Kumar S, D 'Emilia DM, Rayudu PV, et al. Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proc Natl Acad Sci USA 1997; 94: 5923-8.
  • 25
    • 0032745167 scopus 로고    scopus 로고
    • Positive inotropic action of NMDA receptor antagonist (+)-MK801 in rat heart
    • Huang CF, Su MJ. Positive inotropic action of NMDA receptor antagonist (+)-MK801 in rat heart. J Biomed Sci 1999; 6: 387-98.
    • (1999) J Biomed Sci , vol.6 , pp. 387-398
    • Huang, C.F.1    Su, M.J.2
  • 26
    • 0033054770 scopus 로고    scopus 로고
    • Arrhythmias induced by myocardial ischaemia-reperfusion are sensitive to ionotropic excitatory amino acid receptor antagonists
    • D'Amico M, Di FC, Rossi F, Rossi F. Arrhythmias induced by myocardial ischaemia-reperfusion are sensitive to ionotropic excitatory amino acid receptor antagonists. Eur J Pharmacol 1999; 366: 167-74.
    • (1999) Eur J Pharmacol , vol.366 , pp. 167-174
    • D'Amico, M.1    Di, F.C.2    Rossi, F.3    Rossi, F.4
  • 27
    • 0035806896 scopus 로고    scopus 로고
    • Taurine prevents the decrease in expression and secretion of extracellular superoxide dismutase induced by homocysteine: Amelioration of homocysteine-induced endoplasmic reticulum stress by taurine
    • Nonaka H, Tsujino T, Watari Y, Emoto N, Yokoyama M. Taurine prevents the decrease in expression and secretion of extracellular superoxide dismutase induced by homocysteine: amelioration of homocysteine-induced endoplasmic reticulum stress by taurine. Circulation 2001; 104: 1165-70.
    • (2001) Circulation , vol.104 , pp. 1165-1170
    • Nonaka, H.1    Tsujino, T.2    Watari, Y.3    Emoto, N.4    Yokoyama, M.5
  • 29
    • 0031965641 scopus 로고    scopus 로고
    • Homocysteine-induced nitric oxide production in vascular smooth-muscle cells by NFkappa B-dependent transcriptional activation of Nos2
    • Welch GN, Upchurch GR Jr, Farivar RS. Homocysteine-induced nitric oxide production in vascular smooth-muscle cells by NFkappa B-dependent transcriptional activation of Nos2. Proc Assoc Am Physicians 1998; 110: 22-31.
    • (1998) Proc Assoc Am Physicians , vol.110 , pp. 22-31
    • Welch, G.N.1    Upchurch Jr, G.R.2    Farivar, R.S.3
  • 30
    • 27644581655 scopus 로고    scopus 로고
    • Mitochondrial mechanism of oxidative stress and systemic hypertension in hyperhomocysteinemia
    • Tyagi N, Moshal KS, Ovechkin AV, Rodriguez W, Steed M, Henderson B, et al. Mitochondrial mechanism of oxidative stress and systemic hypertension in hyperhomocysteinemia. J Cell Biochem 2005; 96: 665-71.
    • (2005) J Cell Biochem , vol.96 , pp. 665-671
    • Tyagi, N.1    Moshal, K.S.2    Ovechkin, A.V.3    Rodriguez, W.4    Steed, M.5    Henderson, B.6
  • 32
    • 34248595219 scopus 로고    scopus 로고
    • Arrhythmogenic ion-channel remodeling in the heart: Heart failure, myocardial infarction, and atrial fibrillation
    • Nattel S, Maguy A, Le BS, Yeh YH. Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation. Physiol Rev 2007; 87: 425-56.
    • (2007) Physiol Rev , vol.87 , pp. 425-456
    • Nattel, S.1    Maguy, A.2    Le, B.S.3    Yeh, Y.H.4
  • 33
    • 0027218911 scopus 로고
    • The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system
    • Gourdie RG, Severs NJ, Green CR, Rothery S, Germroth P, Thompson RP. The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system. J Cell Sci 1993; 105 (Pt 4): 985-91.
    • (1993) J Cell Sci , vol.105 , Issue.PART 4 , pp. 985-991
    • Gourdie, R.G.1    Severs, N.J.2    Green, C.R.3    Rothery, S.4    Germroth, P.5    Thompson, R.P.6
  • 34
    • 0027405004 scopus 로고
    • Distinct patterns of connexin expression in canine Purkinje fibers and ventricular muscle
    • Kanter HL, Laing JG, Beau SL, Beyer EC, Saffitz JE. Distinct patterns of connexin expression in canine Purkinje fibers and ventricular muscle. Circ Res 1993; 72: 1124-31.
    • (1993) Circ Res , vol.72 , pp. 1124-1131
    • Kanter, H.L.1    Laing, J.G.2    Beau, S.L.3    Beyer, E.C.4    Saffitz, J.E.5
  • 35
    • 0028024953 scopus 로고
    • Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties
    • Davis LM, Kanter HL, Beyer EC, Saffitz JE. Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties. J Am Coll Cardiol 1994; 24: 1124-32.
    • (1994) J Am Coll Cardiol , vol.24 , pp. 1124-1132
    • Davis, L.M.1    Kanter, H.L.2    Beyer, E.C.3    Saffitz, J.E.4
  • 36
  • 38
    • 0033596919 scopus 로고    scopus 로고
    • Conduction disturbances and increased atrial vulnerability in Connexin40-deficient mice analyzed by transesophageal stimulation
    • Hagendorff A, Schumacher B, Kirchhoff S, Luderitz B, Willecke K. Conduction disturbances and increased atrial vulnerability in Connexin40-deficient mice analyzed by transesophageal stimulation. Circulation 1999; 99: 1508-15.
    • (1999) Circulation , vol.99 , pp. 1508-1515
    • Hagendorff, A.1    Schumacher, B.2    Kirchhoff, S.3    Luderitz, B.4    Willecke, K.5
  • 39
    • 9144245551 scopus 로고    scopus 로고
    • Replacement of connexin40 by connexin45 in the mouse: Impact on cardiac electrical conduction
    • Alcoléa S, Jarry-Guichard T, de Bakker J, Gonzàlez D, Lamers W, Coppen S, et al. Replacement of connexin40 by connexin45 in the mouse: impact on cardiac electrical conduction. Circ Res 2004; 94: 100-9.
    • (2004) Circ Res , vol.94 , pp. 100-109
    • Alcoléa, S.1    Jarry-Guichard, T.2    de Bakker, J.3    Gonzàlez, D.4    Lamers, W.5    Coppen, S.6
  • 41
    • 0034957206 scopus 로고    scopus 로고
    • Gating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent protein
    • Bukauskas FF, Bukauskiene A, Bennett MV, Verselis VK. Gating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent protein. Biophys J 2001; 81: 137-52.
    • (2001) Biophys J , vol.81 , pp. 137-152
    • Bukauskas, F.F.1    Bukauskiene, A.2    Bennett, M.V.3    Verselis, V.K.4
  • 42
    • 20444465223 scopus 로고    scopus 로고
    • Functional properties of mouse connexin30.2 expressed in the conduction system of the heart
    • Kreuzberg MM, Sohl G, Kim JS, Verselis VK, Willecke K, Bukauskas FF. Functional properties of mouse connexin30.2 expressed in the conduction system of the heart. Circ Res 2005; 96: 1169-77.
    • (2005) Circ Res , vol.96 , pp. 1169-1177
    • Kreuzberg, M.M.1    Sohl, G.2    Kim, J.S.3    Verselis, V.K.4    Willecke, K.5    Bukauskas, F.F.6
  • 43
    • 0029001434 scopus 로고
    • Biophysical properties of gap junction channels formed by mouse connexin40 in induced pairs of transfected human HeLa cells
    • Bukauskas FF, Elfgang C, Willecke K, Weingart R. Biophysical properties of gap junction channels formed by mouse connexin40 in induced pairs of transfected human HeLa cells. Biophys J 1995; 68: 2289-98.
    • (1995) Biophys J , vol.68 , pp. 2289-2298
    • Bukauskas, F.F.1    Elfgang, C.2    Willecke, K.3    Weingart, R.4
  • 44
    • 0032498522 scopus 로고    scopus 로고
    • Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart
    • Coppen SR, Dupont E, Rothery S, Severs NJ. Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart. Circ Res 1998; 82: 232-43.
    • (1998) Circ Res , vol.82 , pp. 232-243
    • Coppen, S.R.1    Dupont, E.2    Rothery, S.3    Severs, N.J.4
  • 45
    • 0020531650 scopus 로고
    • Cellular electrophysiologic characteristics of chronically infarcted myocardium in dogs susceptible to sustained ventricular tachyarrhythmias
    • Spear JF, Michelson EL, Moore EN. Cellular electrophysiologic characteristics of chronically infarcted myocardium in dogs susceptible to sustained ventricular tachyarrhythmias. J Am Coll Cardiol 1983; 1: 1099-110.
    • (1983) J Am Coll Cardiol , vol.1 , pp. 1099-1110
    • Spear, J.F.1    Michelson, E.L.2    Moore, E.N.3
  • 46
  • 47
    • 33750001478 scopus 로고    scopus 로고
    • Connexin-mediated cardiac impulse propagation: Connexin 30.2 slows atrioventricular conduction in mouse heart
    • Kreuzberg MM, Willecke K, Bukauskas FF. Connexin-mediated cardiac impulse propagation: connexin 30.2 slows atrioventricular conduction in mouse heart. Trends Cardiovasc Med 2006; 16: 266-72.
    • (2006) Trends Cardiovasc Med , vol.16 , pp. 266-272
    • Kreuzberg, M.M.1    Willecke, K.2    Bukauskas, F.F.3
  • 48
    • 0036083484 scopus 로고    scopus 로고
    • Cx40 and Cx43 expression ratio influences heteromeric/ heterotypic gap junction channel properties
    • Cottrell GT, Wu Y, Burt JM. Cx40 and Cx43 expression ratio influences heteromeric/ heterotypic gap junction channel properties. Am J Physiol Cell Physiol 2002; 282: C1469-82.
    • (2002) Am J Physiol Cell Physiol , vol.282
    • Cottrell, G.T.1    Wu, Y.2    Burt, J.M.3
  • 49
    • 4744341926 scopus 로고    scopus 로고
    • Altered connexin43 expression produces arrhythmia substrate in heart failure
    • Poelzing S, Rosenbaum DS. Altered connexin43 expression produces arrhythmia substrate in heart failure. Am J Physiol Heart Circ Physiol 2004; 287: H1762-70.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Poelzing, S.1    Rosenbaum, D.S.2
  • 50
    • 11844254718 scopus 로고    scopus 로고
    • Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A
    • Ai X, Pogwizd SM. Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A. Circ Res 2005; 96: 54-63.
    • (2005) Circ Res , vol.96 , pp. 54-63
    • Ai, X.1    Pogwizd, S.M.2
  • 51
    • 4944249400 scopus 로고    scopus 로고
    • Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy
    • Akar FG, Spragg DD, Tunin RS, Kass DA, Tomaselli GF. Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy. Circ Res 2004; 95: 717-25.
    • (2004) Circ Res , vol.95 , pp. 717-725
    • Akar, F.G.1    Spragg, D.D.2    Tunin, R.S.3    Kass, D.A.4    Tomaselli, G.F.5
  • 52
    • 0029145602 scopus 로고
    • Myocardial gap junction organization in ischemia and infarction
    • Peters NS. Myocardial gap junction organization in ischemia and infarction. Microsc Res Tech 1995; 31: 375-86.
    • (1995) Microsc Res Tech , vol.31 , pp. 375-386
    • Peters, N.S.1
  • 53
    • 0031055039 scopus 로고    scopus 로고
    • Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia
    • Peters NS, Coromilas J, Severs NJ, Wit AL. Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia. Circulation 1997; 95: 988-96.
    • (1997) Circulation , vol.95 , pp. 988-996
    • Peters, N.S.1    Coromilas, J.2    Severs, N.J.3    Wit, A.L.4
  • 54
    • 0033607553 scopus 로고    scopus 로고
    • Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts
    • Matsushita T, Oyamada M, Fujimoto K, Yasuda Y, Masuda S, Wada Y, et al. Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts. Circ Res 1999; 85: 1046-55.
    • (1999) Circ Res , vol.85 , pp. 1046-1055
    • Matsushita, T.1    Oyamada, M.2    Fujimoto, K.3    Yasuda, Y.4    Masuda, S.5    Wada, Y.6
  • 55
    • 0034035839 scopus 로고    scopus 로고
    • Ventricular contraction abnormalities in dilated cardiomyopathy: Effect of biventricular pacing to correct interventricular dyssynchrony
    • Kerwin WF, Botvinick EH, O'Connell JW, Merrick SH, DeMarco T, Chatterjee K, et al. Ventricular contraction abnormalities in dilated cardiomyopathy: effect of biventricular pacing to correct interventricular dyssynchrony. J Am Coll Cardiol, 2000; 35: 1221-7.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1221-1227
    • Kerwin, W.F.1    Botvinick, E.H.2    O'Connell, J.W.3    Merrick, S.H.4    DeMarco, T.5    Chatterjee, K.6
  • 57
    • 0021997481 scopus 로고
    • Electrophysiologic and anatomic basis for fractionated electrograms recorded from healed myocardial infarcts
    • Gardner PI, Ursell PC, Fenoglio JJ Jr, Wit AL. Electrophysiologic and anatomic basis for fractionated electrograms recorded from healed myocardial infarcts. Circulation 1985; 72: 596-611.
    • (1985) Circulation , vol.72 , pp. 596-611
    • Gardner, P.I.1    Ursell, P.C.2    Fenoglio Jr, J.J.3    Wit, A.L.4
  • 58
    • 0034620495 scopus 로고    scopus 로고
    • Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice
    • Lerner DL, Yamada KA, Schuessler RB, Saffitz JE. Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice. Circulation 2000; 101: 547-52.
    • (2000) Circulation , vol.101 , pp. 547-552
    • Lerner, D.L.1    Yamada, K.A.2    Schuessler, R.B.3    Saffitz, J.E.4
  • 59
    • 0035806899 scopus 로고    scopus 로고
    • Heterogeneous expression of Gap junction channels in the heart leads to conduction defects and ventricular dysfunction
    • Gutstein DE, Morley GE, Vaidya D, Liu F, Chen FL, Stuhlmann H, et al. Heterogeneous expression of Gap junction channels in the heart leads to conduction defects and ventricular dysfunction. Circulation 2001; 104: 1194-9.
    • (2001) Circulation , vol.104 , pp. 1194-1199
    • Gutstein, D.E.1    Morley, G.E.2    Vaidya, D.3    Liu, F.4    Chen, F.L.5    Stuhlmann, H.6
  • 60
    • 0035895649 scopus 로고    scopus 로고
    • Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43
    • Gutstein DE, Morley GE, Tamaddon H, Vaidya D, Schneider MD, Chen J, et al. Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43. Circ Res 2001; 88: 333-9.
    • (2001) Circ Res , vol.88 , pp. 333-339
    • Gutstein, D.E.1    Morley, G.E.2    Tamaddon, H.3    Vaidya, D.4    Schneider, M.D.5    Chen, J.6
  • 61
    • 0037019966 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes
    • Petrich BG, Gong X, Lerner DL, Wang X, Brown JH, Saffitz JE, et al. c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes. Circ Res 2002; 91: 640-7.
    • (2002) Circ Res , vol.91 , pp. 640-647
    • Petrich, B.G.1    Gong, X.2    Lerner, D.L.3    Wang, X.4    Brown, J.H.5    Saffitz, J.E.6
  • 62
    • 0141707855 scopus 로고    scopus 로고
    • Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure
    • Akar FG, Rosenbaum DS. Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure. Circ Res 2003; 93: 638-45.
    • (2003) Circ Res , vol.93 , pp. 638-645
    • Akar, F.G.1    Rosenbaum, D.S.2
  • 63
    • 0036741255 scopus 로고    scopus 로고
    • Heterogeneous loss of connexin43 protein in nonischemic dilated cardiomyopathy with ventricular tachycardia
    • Kitamura H, Ohnishi Y, Yoshida A. Heterogeneous loss of connexin43 protein in nonischemic dilated cardiomyopathy with ventricular tachycardia. J Cardiovasc Electrophysiol 2002; 13: 865-70.
    • (2002) J Cardiovasc Electrophysiol , vol.13 , pp. 865-870
    • Kitamura, H.1    Ohnishi, Y.2    Yoshida, A.3
  • 64
    • 3442896550 scopus 로고    scopus 로고
    • Cardiac connexins Cx43 and Cx45: Formation of diverse gap junction channels with diverse electrical properties
    • Desplantez T, Halliday D, Dupont E, Weingart R. Cardiac connexins Cx43 and Cx45: formation of diverse gap junction channels with diverse electrical properties. Pflugers Arch 2004; 448: 363-75.
    • (2004) Pflugers Arch , vol.448 , pp. 363-375
    • Desplantez, T.1    Halliday, D.2    Dupont, E.3    Weingart, R.4
  • 65
    • 0037205321 scopus 로고    scopus 로고
    • Connexin43 and connexin45 form heteromeric gap junction channels in which individual components determine permeability and regulation
    • Martinez AD, Hayrapetyan V, Moreno AP, Beyer EC. Connexin43 and connexin45 form heteromeric gap junction channels in which individual components determine permeability and regulation. Circ Res 2002; 90: 1100-7.
    • (2002) Circ Res , vol.90 , pp. 1100-1107
    • Martinez, A.D.1    Hayrapetyan, V.2    Moreno, A.P.3    Beyer, E.C.4
  • 66
  • 67
    • 4344563965 scopus 로고    scopus 로고
    • Remodeling of sinus node function in patients with congestive heart failure: Reduction in sinus node reserve
    • Sanders P, Kistler PM, Morton JB, Spence SJ, Kalman JM. Remodeling of sinus node function in patients with congestive heart failure: reduction in sinus node reserve. Circulation 2004; 110: 897-903.
    • (2004) Circulation , vol.110 , pp. 897-903
    • Sanders, P.1    Kistler, P.M.2    Morton, J.B.3    Spence, S.J.4    Kalman, J.M.5
  • 68
    • 0141839060 scopus 로고    scopus 로고
    • Electrical remodeling of the atria in congestive heart failure: Electrophysiological and electroanatomic mapping in humans
    • Sanders P, Morton JB, Davidson NC, Spence SJ, Vohra JK, Sparks PB, et al. Electrical remodeling of the atria in congestive heart failure: electrophysiological and electroanatomic mapping in humans. Circulation 2003; 108: 1461-8.
    • (2003) Circulation , vol.108 , pp. 1461-1468
    • Sanders, P.1    Morton, J.B.2    Davidson, N.C.3    Spence, S.J.4    Vohra, J.K.5    Sparks, P.B.6
  • 69
    • 77049325700 scopus 로고
    • Physiologic evidence for a dual A-V transmission system
    • Moe GK, Preston JB, Burlington H. Physiologic evidence for a dual A-V transmission system. Circ Res 1956; 4: 357-75.
    • (1956) Circ Res , vol.4 , pp. 357-375
    • Moe, G.K.1    Preston, J.B.2    Burlington, H.3
  • 70
    • 12844282083 scopus 로고    scopus 로고
    • Historical perspective of studies on impulse formation and conduction in the AV Node
    • Mazgalev TN and Tchou PJ, Eds, Armonk, NY: Futura
    • Watanabe Y, Hata T. Historical perspective of studies on impulse formation and conduction in the AV Node. In: Mazgalev TN and Tchou PJ, Eds., Nodal Electrophysiology: a view from the millennium. Armonk, NY: Futura, 2000; pp. 49-59.
    • (2000) Nodal Electrophysiology: A view from the millennium , pp. 49-59
    • Watanabe, Y.1    Hata, T.2
  • 71
    • 0015043095 scopus 로고
    • Circus movement within the AV node as a basis for supraventricular tachycardia as shown by multiple microelectrode recording in the isolated rabbit heart
    • Janse MJ, Van Capelle FJ, Freud GE, Durrer D. Circus movement within the AV node as a basis for supraventricular tachycardia as shown by multiple microelectrode recording in the isolated rabbit heart. Circ Res 1971; 28: 403-14.
    • (1971) Circ Res , vol.28 , pp. 403-414
    • Janse, M.J.1    Van Capelle, F.J.2    Freud, G.E.3    Durrer, D.4
  • 74
    • 0015867360 scopus 로고
    • Demonstration of dual A-V nodal pathways in patients with paroxysmal supraventricular tachycardia
    • Denes P, Wu D, Dhingra RC, Chuquimia R, Rosen KM. Demonstration of dual A-V nodal pathways in patients with paroxysmal supraventricular tachycardia. Circulation 1973; 48: 549-55.
    • (1973) Circulation , vol.48 , pp. 549-555
    • Denes, P.1    Wu, D.2    Dhingra, R.C.3    Chuquimia, R.4    Rosen, K.M.5
  • 75
    • 27744522672 scopus 로고    scopus 로고
    • Atrioventricular nodal reverse facilitation in connexin40-deficient mice
    • Zhu W, Saba S, Link MS, Bak E, Homoud MK, Estes NA 3rd, et al. Atrioventricular nodal reverse facilitation in connexin40-deficient mice. Heart Rhythm 2005; 2: 1231-7.
    • (2005) Heart Rhythm , vol.2 , pp. 1231-1237
    • Zhu, W.1    Saba, S.2    Link, M.S.3    Bak, E.4    Homoud, M.K.5    Estes 3rd, N.A.6
  • 76
    • 0034435074 scopus 로고    scopus 로고
    • Genetic determinants of hyperhomocysteinaemia: The roles of cystathionine beta-synthase and 5,10-methylenetetrahydrofolate reductase
    • Blom HJ. Genetic determinants of hyperhomocysteinaemia: the roles of cystathionine beta-synthase and 5,10-methylenetetrahydrofolate reductase. Eur J Pediatr 2000; 159 (Suppl 3): S208-S212.
    • (2000) Eur J Pediatr , vol.159 , Issue.SUPPL. 3
    • Blom, H.J.1
  • 77
    • 0018651563 scopus 로고
    • Sulphr containing amino acids in chronic renal failure with particular reference to homocystine and cysteinehomocysteine mixed disulphide
    • Wilcken DE, Gupta VJ. Sulphr containing amino acids in chronic renal failure with particular reference to homocystine and cysteinehomocysteine mixed disulphide. Eur J Clin Invest 1979; 9: 301-7.
    • (1979) Eur J Clin Invest , vol.9 , pp. 301-307
    • Wilcken, D.E.1    Gupta, V.J.2
  • 78
    • 0141468244 scopus 로고    scopus 로고
    • Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention
    • Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 2003; 108: 2154-69.
    • (2003) Circulation , vol.108 , pp. 2154-2169
    • Sarnak, M.J.1    Levey, A.S.2    Schoolwerth, A.C.3    Coresh, J.4    Culleton, B.5    Hamm, L.L.6
  • 79
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351: 1296-305.
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.Y.5
  • 80
    • 10944256578 scopus 로고    scopus 로고
    • Clinical and pathologic characteristics of dilated cardiomyopathy in hemodialysis patients
    • Aoki J, Ikari Y, Nakajima H. Clinical and pathologic characteristics of dilated cardiomyopathy in hemodialysis patients. Kidney Int 2005; 67: 333-40.
    • (2005) Kidney Int , vol.67 , pp. 333-340
    • Aoki, J.1    Ikari, Y.2    Nakajima, H.3
  • 81
    • 0018651563 scopus 로고
    • Sulpher containing amino acids in chronic renal failure with particular reference to homocystine and cysteinehomocysteine mixed disulphide
    • Wilcken DE, Gupta VJ. Sulpher containing amino acids in chronic renal failure with particular reference to homocystine and cysteinehomocysteine mixed disulphide. Eur J Clin Invest 1979; 9: 301-7.
    • (1979) Eur J Clin Invest , vol.9 , pp. 301-307
    • Wilcken, D.E.1    Gupta, V.J.2
  • 82
    • 33745697873 scopus 로고    scopus 로고
    • Laser doppler flowmetry detection of endothelial dysfunction in end-stage renal disease patients: Correlation with cardiovascular risk
    • Kruger A, Stewart J, Sahityani R, O'Riordan E, Thompson C, Adler S, et al. Laser doppler flowmetry detection of endothelial dysfunction in end-stage renal disease patients: correlation with cardiovascular risk. Kidney Int 2006; 70: 157-64.
    • (2006) Kidney Int , vol.70 , pp. 157-164
    • Kruger, A.1    Stewart, J.2    Sahityani, R.3    O'Riordan, E.4    Thompson, C.5    Adler, S.6
  • 84
    • 0037133633 scopus 로고    scopus 로고
    • Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease
    • Zoccali C, Mallamaci F, Parlongo S, Cutrupi S, Benedetto FA, Tripepi G, et al. Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease. Circulation 2002; 105: 1354-9.
    • (2002) Circulation , vol.105 , pp. 1354-1359
    • Zoccali, C.1    Mallamaci, F.2    Parlongo, S.3    Cutrupi, S.4    Benedetto, F.A.5    Tripepi, G.6
  • 85
    • 49749091685 scopus 로고    scopus 로고
    • Disordered mineral metabolism in hemodialysis patients: An analysis of cumulative effects in the Hemodialysis (HEMO) Study
    • Wald R, Sarnak MJ, Tighiouart H. Disordered mineral metabolism in hemodialysis patients: an analysis of cumulative effects in the Hemodialysis (HEMO) Study. Am J Kidney Dis 2008; 52: 531-40.
    • (2008) Am J Kidney Dis , vol.52 , pp. 531-540
    • Wald, R.1    Sarnak, M.J.2    Tighiouart, H.3
  • 88
    • 0020591364 scopus 로고
    • Chronic beta blockade therapy in patients after myocardial infarction
    • Pratt CM, Roberts R. Chronic beta blockade therapy in patients after myocardial infarction. Am J Cardiol 1983; 52: 661-4.
    • (1983) Am J Cardiol , vol.52 , pp. 661-664
    • Pratt, C.M.1    Roberts, R.2
  • 89
    • 0038408916 scopus 로고    scopus 로고
    • Carvedilol increases two-year survival in dialysis patients with dilated cardiomyopathy: A prospective, placebo-controlled trial
    • Cice G, Ferrara L, D'Andrea A, D'Isa S, Di Benedetto A, Cittadini A, et al. Carvedilol increases two-year survival in dialysis patients with dilated cardiomyopathy: a prospective, placebo-controlled trial. J Am Coll Cardiol 2003; 41: 1438-44.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1438-1444
    • Cice, G.1    Ferrara, L.2    D'Andrea, A.3    D'Isa, S.4    Di Benedetto, A.5    Cittadini, A.6
  • 90
    • 0036559911 scopus 로고    scopus 로고
    • Congestive heart failure due to systolic dysfunction: The Cinderella of cardiovascular management in dialysis patients
    • Ritz E, Dikow R, Adamzcak M, Zeier M. Congestive heart failure due to systolic dysfunction: the Cinderella of cardiovascular management in dialysis patients. Semin Dial 2002; 15: 135-40.
    • (2002) Semin Dial , vol.15 , pp. 135-140
    • Ritz, E.1    Dikow, R.2    Adamzcak, M.3    Zeier, M.4
  • 91
    • 34548566329 scopus 로고    scopus 로고
    • Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and endstage renal disease: A randomized controlled trial
    • Jamison RL, Hartigan P, Kaufman JS, Goldfarb DS, Warren SR, Guarino PD, et al. Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and endstage renal disease: a randomized controlled trial. JAMA 2007; 298: 1163-70.
    • (2007) JAMA , vol.298 , pp. 1163-1170
    • Jamison, R.L.1    Hartigan, P.2    Kaufman, J.S.3    Goldfarb, D.S.4    Warren, S.R.5    Guarino, P.D.6
  • 92
    • 33750072018 scopus 로고    scopus 로고
    • Effect of aggressive risk factor modification on cardiac events and myocardial ischaemia in patients with chronic kidney disease
    • Rakhit DJ, Marwick TH, Armstrong KA, Johnson DW, Leano R, Isbel NM. Effect of aggressive risk factor modification on cardiac events and myocardial ischaemia in patients with chronic kidney disease. Heart 2006; 92: 1402-8.
    • (2006) Heart , vol.92 , pp. 1402-1408
    • Rakhit, D.J.1    Marwick, T.H.2    Armstrong, K.A.3    Johnson, D.W.4    Leano, R.5    Isbel, N.M.6
  • 93
    • 0037164104 scopus 로고    scopus 로고
    • Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis
    • The Homocysteine Studies Collaboration
    • The Homocysteine Studies Collaboration. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA 2002; 288: 2015-22.
    • (2002) JAMA , vol.288 , pp. 2015-2022
  • 94
    • 0033533527 scopus 로고    scopus 로고
    • Homocyst(e)ine and cardiovascular disease: A critical review of the epidemiologic evidence
    • Eikelboom JW, Lonn E, Genest J, Jr, Hankey G, Yusuf S. Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence. Ann Intern Med 1999; 131: 363-75.
    • (1999) Ann Intern Med , vol.131 , pp. 363-375
    • Eikelboom, J.W.1    Lonn, E.2    Genest Jr, J.3    Hankey, G.4    Yusuf, S.5
  • 95
    • 33645753544 scopus 로고    scopus 로고
    • Homocysteine lowering with folic acid and B vitamins in vascular disease
    • Lonn E, Yusuf S, Arnold MJ, Sheridan P, Pogue J, Micks M, et al. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 2006; 354: 1567-77.
    • (2006) N Engl J Med , vol.354 , pp. 1567-1577
    • Lonn, E.1    Yusuf, S.2    Arnold, M.J.3    Sheridan, P.4    Pogue, J.5    Micks, M.6
  • 96
    • 1342309318 scopus 로고    scopus 로고
    • Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: The Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial
    • Toole JF, Malinow MR, Chambless LE, Spence JD, Pettigrew LC, Howard VJ, et al. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 2004; 291: 565-75.
    • (2004) JAMA , vol.291 , pp. 565-575
    • Toole, J.F.1    Malinow, M.R.2    Chambless, L.E.3    Spence, J.D.4    Pettigrew, L.C.5    Howard, V.J.6
  • 97
    • 40849110313 scopus 로고    scopus 로고
    • Homocysteine lowering with folic acid and B vitamins in people with chronic kidney disease - results of the renal Hope-2 study
    • Mann JF, Sheridan P, McQueen MJ, Held C, Arnold JM, Fodor G, et al. Homocysteine lowering with folic acid and B vitamins in people with chronic kidney disease - results of the renal Hope-2 study. Nephrol Dial Transplant 2008; 23: 645-53.
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 645-653
    • Mann, J.F.1    Sheridan, P.2    McQueen, M.J.3    Held, C.4    Arnold, J.M.5    Fodor, G.6
  • 99
    • 34447626134 scopus 로고    scopus 로고
    • Homocysteine-lowering therapy does not affect inflammatory markers of atherosclerosis in patients with stable coronary artery disease
    • Bleie Ø, Semb AG, Grundt H, Nordrehaug JE, Vollset SE, Ueland PM, et al. Homocysteine-lowering therapy does not affect inflammatory markers of atherosclerosis in patients with stable coronary artery disease. J Intern Med 2007; 262: 244-53.
    • (2007) J Intern Med , vol.262 , pp. 244-253
    • Bleie, Ø.1    Semb, A.G.2    Grundt, H.3    Nordrehaug, J.E.4    Vollset, S.E.5    Ueland, P.M.6
  • 100
    • 0020591364 scopus 로고
    • Chronic beta blockade therapy in patients after myocardial infarction
    • Pratt CM, Roberts R. Chronic beta blockade therapy in patients after myocardial infarction. Am J Cardiol 1983; 52: 661-4.
    • (1983) Am J Cardiol , vol.52 , pp. 661-664
    • Pratt, C.M.1    Roberts, R.2
  • 101
    • 0032858535 scopus 로고    scopus 로고
    • Homocysteine levels in hypertensive patients with a history of cardiac or cerebral atherothrombotic events
    • Sharabi Y, Doolman R, Rosenthal T, Grossman E, Rachima-Maoz C, Nussinovitch N, et al. Homocysteine levels in hypertensive patients with a history of cardiac or cerebral atherothrombotic events. Am J Hypertens 1999; 12: 766-71.
    • (1999) Am J Hypertens , vol.12 , pp. 766-771
    • Sharabi, Y.1    Doolman, R.2    Rosenthal, T.3    Grossman, E.4    Rachima-Maoz, C.5    Nussinovitch, N.6
  • 103
    • 70749159902 scopus 로고    scopus 로고
    • The beneficial effect of high loading dose of rosuvastatin before percutaneous coronary intervention in patients with acute coronary syndrome
    • Epub ahead of print
    • Yun KH, Jeong MH, Oh SK, Rhee SJ, Park EM, Lee EM, et al. The beneficial effect of high loading dose of rosuvastatin before percutaneous coronary intervention in patients with acute coronary syndrome. Int J Cardiol 2008; [Epub ahead of print]
    • (2008) Int J Cardiol
    • Yun, K.H.1    Jeong, M.H.2    Oh, S.K.3    Rhee, S.J.4    Park, E.M.5    Lee, E.M.6
  • 104
    • 34548798271 scopus 로고    scopus 로고
    • Efficacy and safety of statin monotherapy in older adults: A meta-analysis
    • Roberts CG, Guallar E, Rodriguez A. Efficacy and safety of statin monotherapy in older adults: a meta-analysis. J Gerontol A Biol Sci Med Sci 2007; 62: 879-87.
    • (2007) J Gerontol A Biol Sci Med Sci , vol.62 , pp. 879-887
    • Roberts, C.G.1    Guallar, E.2    Rodriguez, A.3
  • 105
    • 0033578187 scopus 로고    scopus 로고
    • Serum homocysteine increases after therapy with fenofibrate or bezafibrate
    • Dierkes J, Westphal S, Luley C. Serum homocysteine increases after therapy with fenofibrate or bezafibrate. Lancet 1999; 354: 219-20.
    • (1999) Lancet , vol.354 , pp. 219-220
    • Dierkes, J.1    Westphal, S.2    Luley, C.3
  • 108
    • 43349084839 scopus 로고    scopus 로고
    • Hydrogen sulfide inhibits myocardial injury induced by homocysteine in rats
    • Chang L, Geng B, Yu F, Zhao J, Jiang H, Du J, et al. Hydrogen sulfide inhibits myocardial injury induced by homocysteine in rats. Amino Acids 2008; 34: 573-85.
    • (2008) Amino Acids , vol.34 , pp. 573-585
    • Chang, L.1    Geng, B.2    Yu, F.3    Zhao, J.4    Jiang, H.5    Du, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.