Cytokine-induced nitric oxide inhibits mitochondrial energy production and induces myocardial dysfunction in endotoxin-treated rat hearts

Journal of Molecular and Cellular Cardiology

Volumn 37, Issue 3, 2004, Pages 775-784

  Tatsumi, Tetsuya ^a   Akashi, Kazuko ^a   Keira, Natsuya ^a   Matoba, Satoaki ^a   Mano, Akiko ^a   Shiraishi, Jun ^a   Yamanaka, Satoshi ^a   Kobara, Miyuki ^a   Hibino, Nobuhiro ^b   Hosokawa, Satoru ^b   Asayama, Jun ^a   Fushiki, Shinji ^a   Fliss, Henry ^c   Nakagawa, Masao ^a   Matsubara, Hiroaki ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b EISAI CO LTD   (Japan)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Cytokine; Endotoxin shock; Lipopolysaccharide; Mitochondrial dysfunction; Nitric oxide

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; CYCLIC GMP; CYTOKINE; ENDOTOXIN; GUANYLATE CYCLASE; LIPOPOLYSACCHARIDE; METHYLENE BLUE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE);

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENERGY YIELD; HEART; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTILITY; HEART PERFORMANCE; IMMUNOLOGICAL PROCEDURES; MALE; MITOCHONDRION; MUSCLE CELL; MYOCARDIAL DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEPTIC SHOCK; STATISTICAL SIGNIFICANCE; SYSTOLIC BLOOD PRESSURE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; BLOOD PRESSURE; CARDIOMYOPATHIES; CYTOKINES; ENERGY METABOLISM; LIPOPOLYSACCHARIDES; MALE; MITOCHONDRIA, HEART; MYOCARDIUM; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY;

EID: 4444346594     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.06.014     Document Type: Article

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