In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 1, 2008, Pages

  Mani, Santhosh K ^a   Shiraishi, Hirokazu ^a   Balasubramanian, Sundaravadivel ^a   Yamane, Kentaro ^a   Chellaiah, Meenakshi ^c   Cooper, George ^a,b   Banik, Naren ^a   Zile, Michael R ^a,b   Kuppuswamy, Dhandapani ^a,b,d  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^c UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cardiomyopathy; Caspases; Cytoskeleton; Heart failure

Indexed keywords

CALPAIN; CALPASTATIN; CALPEPTIN; CASPASE 3; CASPASE INHIBITOR; GELSOLIN; HISTONE H2B; N BENZOYLCARBONYLVALYLALANYLASPARTYLFLUOROMETHYLKETONE; UNCLASSIFIED DRUG; BENZYLOXYCARBONYL VALYL ASPARTIC ACID FLUOROMETHYL KETONE; BENZYLOXYCARBONYL-VALYL-ASPARTIC ACID FLUOROMETHYL KETONE; CASP3 PROTEIN, RAT; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDE; HISTONE; PEPTIDE CHLOROMETHYL KETONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CAT; CELL LOSS; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART HEMODYNAMICS; HEART MUSCLE CELL; HEART RIGHT VENTRICLE; HEART RIGHT VENTRICLE PRESSURE; HEART VENTRICLE HYPERTROPHY; IN VIVO STUDY; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; CARDIOMEGALY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HEART FAILURE; INTRAVENOUS DRUG ADMINISTRATION; LIGATION; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PULMONARY ARTERY; TIME;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CALPAIN; CARDIOMEGALY; CASPASE 3; CATS; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GELSOLIN; HEART FAILURE; HISTONES; IN SITU NICK-END LABELING; INJECTIONS, INTRAVENOUS; LIGATION; MALE; MYOCYTES, CARDIAC; PHOSPHORYLATION; PULMONARY ARTERY; TIME FACTORS;

EID: 49849088828     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00085.2008     Document Type: Article

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