Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase i

Free Radical Biology and Medicine

Volumn 53, Issue 2, 2012, Pages 216-229

  Sharma, Shruti ^a   Sun, Xutong ^a   Kumar, Sanjiv ^a   Rafikov, Ruslan ^a   Aramburo, Angela ^b   Kalkan, Gokhan ^b   Tian, Jing ^a   Rehmani, Imran ^a   Kallarackal, Suphin ^a   Fineman, Jeffrey R ^b,c   Black, Stephen M ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BH4; CHIP; Free radicals; Hsp70; Hsp90; Mitochondrial dysfunction; Ubiquitination

Indexed keywords

CARNITINE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTECTIVE AGENT;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONGENITAL HEART DISEASE; CONTROLLED STUDY; ENDOTHELIUM CELL; LUNG BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PULMONARY ARTERIAL ENDOTHELIAL CELL; UBIQUITINATION;

ACETYLCARNITINE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANIMALS, NEWBORN; ARGININE; BIOPTERIN; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; GTP CYCLOHYDROLASE; HSP70 HEAT-SHOCK PROTEINS; HYPERTENSION, PULMONARY; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PREGNANCY; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PULMONARY ARTERY; PULMONARY HEART DISEASE; SHEEP; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

OVIS ARIES;

EID: 84862238561     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.03.016     Document Type: Article

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