Restoration of contractility in hyperhomocysteinemia by cardiac-specific deletion of NMDA-R1

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 296, Issue 3, 2009, Pages

  Moshal, Karni S ^a   Kumar, Munish ^a   Tyagi, Neetu ^a   Mishra, Paras K ^a   Metreveli, Naira ^a   Rodriguez, Walter E ^a   Tyagi, Suresh C ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Calcium transient; Mitochondrial matrix metalloproteinase; Mitochondrial permeability; Myocyte mechanics; N methyl d aspartate receptor 1

Indexed keywords

CALCIUM; CRE RECOMBINASE; HOMOCYSTEINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; NITRIC OXIDE; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR; CARRIER PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR1 NMDA RECEPTOR; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM BLOOD LEVEL; CELL SPECIFICITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENE DELETION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; HYPERHOMOCYSTEINEMIA; MITOCHONDRIAL PERMEABILITY; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; SPECTROPHOTOMETER; WESTERN BLOTTING; ANIMAL; CALCIUM SIGNALING; DISEASE MODEL; GENETICS; HEART CONTRACTION; HEART MITOCHONDRION; METABOLISM; MOUSE MUTANT; OXIDATIVE STRESS; PATHOPHYSIOLOGY;

ANIMALS; CALCIUM SIGNALING; DISEASE MODELS, ANIMAL; HYPERHOMOCYSTEINEMIA; MICE; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; NITRIC OXIDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 64049097756     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00750.2008     Document Type: Article

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