-
1
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson S.P., Bartek J. The DNA-damage response in human biology and disease. Nature 2009, 461:1071-1078.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
2
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou L., Elledge S.J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 2003, 300:1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
3
-
-
0027285362
-
Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid
-
Bennett C.B., Lewis A.L., Baldwin K.K., Resnick M.A. Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid. Proc. Natl. Acad. Sci. U. S. A. 1993, 90:5613-5617.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 5613-5617
-
-
Bennett, C.B.1
Lewis, A.L.2
Baldwin, K.K.3
Resnick, M.A.4
-
4
-
-
0035093737
-
DNA double-strand breaks: signaling, repair and the cancer connection
-
Khanna K.K., Jackson S.P. DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 2001, 27:247-254.
-
(2001)
Nat. Genet.
, vol.27
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
5
-
-
0942268167
-
Repair of DNA double strand breaks by non-homologous end joining
-
Lees-Miller S.P., Meek K. Repair of DNA double strand breaks by non-homologous end joining. Biochimie 2003, 85:1161-1173.
-
(2003)
Biochimie
, vol.85
, pp. 1161-1173
-
-
Lees-Miller, S.P.1
Meek, K.2
-
6
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
7
-
-
0344845194
-
Pathways for mitotic homologous recombination in mammalian cells
-
Helleday T. Pathways for mitotic homologous recombination in mammalian cells. Mutat. Res. 2003, 532:103-115.
-
(2003)
Mutat. Res.
, vol.532
, pp. 103-115
-
-
Helleday, T.1
-
8
-
-
0029808466
-
Cell cycle checkpoints: preventing an identity crisis
-
Elledge S.J. Cell cycle checkpoints: preventing an identity crisis. Science 1996, 274:1664-1672.
-
(1996)
Science
, vol.274
, pp. 1664-1672
-
-
Elledge, S.J.1
-
9
-
-
0142011461
-
The cellular response to DNA double-strand breaks: defining the sensors and mediators
-
Petrini J.H., Stracker T.H. The cellular response to DNA double-strand breaks: defining the sensors and mediators. Trends Cell Biol. 2003, 13:458-462.
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 458-462
-
-
Petrini, J.H.1
Stracker, T.H.2
-
10
-
-
0035930329
-
Human Rad50/Mre11 is a flexible complex that can tether DNA ends
-
de Jager M., van Noort J., van Gent D.C., Dekker C., Kanaar R., Wyman C. Human Rad50/Mre11 is a flexible complex that can tether DNA ends. Mol. Cell 2001, 8:1129-1135.
-
(2001)
Mol. Cell
, vol.8
, pp. 1129-1135
-
-
de Jager, M.1
van Noort, J.2
van Gent, D.C.3
Dekker, C.4
Kanaar, R.5
Wyman, C.6
-
11
-
-
0345732687
-
The Mre11 complex is required for ATM activation and the G2/M checkpoint
-
Carson C.T., Schwartz R.A., Stracker T.H., Lilley C.E., Lee D.V., Weitzman M.D. The Mre11 complex is required for ATM activation and the G2/M checkpoint. EMBO J. 2003, 22:6610-6620.
-
(2003)
EMBO J.
, vol.22
, pp. 6610-6620
-
-
Carson, C.T.1
Schwartz, R.A.2
Stracker, T.H.3
Lilley, C.E.4
Lee, D.V.5
Weitzman, M.D.6
-
12
-
-
0037142619
-
Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest
-
Girard P.M., Riballo E., Begg A.C., Waugh A., Jeggo P.A. Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest. Oncogene 2002, 21:4191-4199.
-
(2002)
Oncogene
, vol.21
, pp. 4191-4199
-
-
Girard, P.M.1
Riballo, E.2
Begg, A.C.3
Waugh, A.4
Jeggo, P.A.5
-
13
-
-
1842431822
-
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
-
Lee J.H., Paull T.T. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science 2004, 304:93-96.
-
(2004)
Science
, vol.304
, pp. 93-96
-
-
Lee, J.H.1
Paull, T.T.2
-
14
-
-
17644409069
-
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
-
Lee J.H., Paull T.T. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science 2005, 308:551-554.
-
(2005)
Science
, vol.308
, pp. 551-554
-
-
Lee, J.H.1
Paull, T.T.2
-
15
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
Uziel T., Lerenthal Y., Moyal L., Andegeko Y., Mittelman L., Shiloh Y. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 2003, 22:5612-5621.
-
(2003)
EMBO J.
, vol.22
, pp. 5612-5621
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
16
-
-
38349008365
-
A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex
-
Dupre A., Boyer-Chatenet L., Sattler R.M., Modi A.P., Lee J.H., Nicolette M.L., Kopelovich L., Jasin M., Baer R., Paull T.T., Gautier J. A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex. Nat. Chem. Biol. 2008, 4:119-125.
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 119-125
-
-
Dupre, A.1
Boyer-Chatenet, L.2
Sattler, R.M.3
Modi, A.P.4
Lee, J.H.5
Nicolette, M.L.6
Kopelovich, L.7
Jasin, M.8
Baer, R.9
Paull, T.T.10
Gautier, J.11
-
17
-
-
0034106722
-
ATM-dependent phosphorylation of nibrin in response to radiation exposure
-
Gatei M., Young D., Cerosaletti K.M., Desai-Mehta A., Spring K., Kozlov S., Lavin M.F., Gatti R.A., Concannon P., Khanna K. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nat. Genet. 2000, 25:115-119.
-
(2000)
Nat. Genet.
, vol.25
, pp. 115-119
-
-
Gatei, M.1
Young, D.2
Cerosaletti, K.M.3
Desai-Mehta, A.4
Spring, K.5
Kozlov, S.6
Lavin, M.F.7
Gatti, R.A.8
Concannon, P.9
Khanna, K.10
-
18
-
-
34250743173
-
Systematic discovery of in vivo phosphorylation networks
-
Linding R., Jensen L.J., Ostheimer G.J., van Vugt M.A., Jorgensen C., Miron I.M., Diella F., Colwill K., Taylor L., Elder K., Metalnikov P., Nguyen V., Pasculescu A., Jin J., Park J.G., Samson L.D., Woodgett J.R., Russell R.B., Bork P., Yaffe M.B., Pawson T. Systematic discovery of in vivo phosphorylation networks. Cell 2007, 129:1415-1426.
-
(2007)
Cell
, vol.129
, pp. 1415-1426
-
-
Linding, R.1
Jensen, L.J.2
Ostheimer, G.J.3
van Vugt, M.A.4
Jorgensen, C.5
Miron, I.M.6
Diella, F.7
Colwill, K.8
Taylor, L.9
Elder, K.10
Metalnikov, P.11
Nguyen, V.12
Pasculescu, A.13
Jin, J.14
Park, J.G.15
Samson, L.D.16
Woodgett, J.R.17
Russell, R.B.18
Bork, P.19
Yaffe, M.B.20
Pawson, T.21
more..
-
19
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R., Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007, 316:1160-1166.
-
(2007)
Science
, vol.316
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
Shiloh, Y.11
Gygi, S.P.12
Elledge, S.J.13
-
20
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
Jazayeri A., Falck J., Lukas C., Bartek J., Smith G.C., Lukas J., Jackson S.P. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat. Cell Biol. 2006, 8:37-45.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.5
Lukas, J.6
Jackson, S.P.7
-
21
-
-
0043066731
-
Regulating mammalian checkpoints through Cdc25 inactivation
-
Donzelli M., Draetta G.F. Regulating mammalian checkpoints through Cdc25 inactivation. EMBO Rep. 2003, 4:671-677.
-
(2003)
EMBO Rep.
, vol.4
, pp. 671-677
-
-
Donzelli, M.1
Draetta, G.F.2
-
22
-
-
0030768948
-
Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
-
Furnari B., Rhind N., Russell P. Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. Science 1997, 277:1495-1497.
-
(1997)
Science
, vol.277
, pp. 1495-1497
-
-
Furnari, B.1
Rhind, N.2
Russell, P.3
-
23
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka S., Huang M., Elledge S.J. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 1998, 282:1893-1897.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
25
-
-
0030611095
-
Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
-
Peng C.Y., Graves P.R., Thoma R.S., Wu Z., Shaw A.S., Piwnica-Worms H. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 1997, 277:1501-1505.
-
(1997)
Science
, vol.277
, pp. 1501-1505
-
-
Peng, C.Y.1
Graves, P.R.2
Thoma, R.S.3
Wu, Z.4
Shaw, A.S.5
Piwnica-Worms, H.6
-
26
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25
-
Sanchez Y., Wong C., Thoma R.S., Richman R., Wu Z., Piwnica-Worms H., Elledge S.J. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 1997, 277:1497-1501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
27
-
-
0033561439
-
Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import
-
Yang J., Winkler K., Yoshida M., Kornbluth S. Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import. EMBO J. 1999, 18:2174-2183.
-
(1999)
EMBO J.
, vol.18
, pp. 2174-2183
-
-
Yang, J.1
Winkler, K.2
Yoshida, M.3
Kornbluth, S.4
-
28
-
-
0035799557
-
Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
-
Bulavin D.V., Higashimoto Y., Popoff I.J., Gaarde W.A., Basrur V., Potapova O., Appella E., Fornace A.J. Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase. Nature 2001, 411:102-107.
-
(2001)
Nature
, vol.411
, pp. 102-107
-
-
Bulavin, D.V.1
Higashimoto, Y.2
Popoff, I.J.3
Gaarde, W.A.4
Basrur, V.5
Potapova, O.6
Appella, E.7
Fornace, A.J.8
-
29
-
-
11344286593
-
MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation
-
Manke I.A., Nguyen A., Lim D., Stewart M.Q., Elia A.E., Yaffe M.B. MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation. Mol. Cell 2005, 17:37-48.
-
(2005)
Mol. Cell
, vol.17
, pp. 37-48
-
-
Manke, I.A.1
Nguyen, A.2
Lim, D.3
Stewart, M.Q.4
Elia, A.E.5
Yaffe, M.B.6
-
30
-
-
33846821915
-
P53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage
-
Reinhardt H.C., Aslanian A.S., Lees J.A., Yaffe M.B. p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage. Cancer Cell 2007, 11:175-189.
-
(2007)
Cancer Cell
, vol.11
, pp. 175-189
-
-
Reinhardt, H.C.1
Aslanian, A.S.2
Lees, J.A.3
Yaffe, M.B.4
-
31
-
-
77957361354
-
DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization
-
Reinhardt H.C., Hasskamp P., Schmedding I., Morandell S., van Vugt M.A., Wang X., Linding R., Ong S.E., Weaver D., Carr S.A., Yaffe M.B. DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization. Mol. Cell 2010, 40:34-49.
-
(2010)
Mol. Cell
, vol.40
, pp. 34-49
-
-
Reinhardt, H.C.1
Hasskamp, P.2
Schmedding, I.3
Morandell, S.4
van Vugt, M.A.5
Wang, X.6
Linding, R.7
Ong, S.E.8
Weaver, D.9
Carr, S.A.10
Yaffe, M.B.11
-
32
-
-
0035848819
-
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
-
Falck J., Mailand N., Syljuasen R.G., Bartek J., Lukas J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 2001, 410:842-847.
-
(2001)
Nature
, vol.410
, pp. 842-847
-
-
Falck, J.1
Mailand, N.2
Syljuasen, R.G.3
Bartek, J.4
Lukas, J.5
-
33
-
-
0034717309
-
Rapid destruction of human Cdc25A in response to DNA damage
-
Mailand N., Falck J., Lukas C., Syljuasen R.G., Welcker M., Bartek J., Lukas J. Rapid destruction of human Cdc25A in response to DNA damage. Science 2000, 288:1425-1429.
-
(2000)
Science
, vol.288
, pp. 1425-1429
-
-
Mailand, N.1
Falck, J.2
Lukas, C.3
Syljuasen, R.G.4
Welcker, M.5
Bartek, J.6
Lukas, J.7
-
34
-
-
0036847320
-
Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability
-
Mailand N., Podtelejnikov A.V., Groth A., Mann M., Bartek J., Lukas J. Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability. EMBO J. 2002, 21:5911-5920.
-
(2002)
EMBO J.
, vol.21
, pp. 5911-5920
-
-
Mailand, N.1
Podtelejnikov, A.V.2
Groth, A.3
Mann, M.4
Bartek, J.5
Lukas, J.6
-
35
-
-
0034232093
-
Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis
-
Molinari M., Mercurio C., Dominguez J., Goubin F., Draetta G.F. Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis. EMBO Rep. 2000, 1:71-79.
-
(2000)
EMBO Rep.
, vol.1
, pp. 71-79
-
-
Molinari, M.1
Mercurio, C.2
Dominguez, J.3
Goubin, F.4
Draetta, G.F.5
-
37
-
-
0034707047
-
The DNA damage response: putting checkpoints in perspective
-
Zhou B.B., Elledge S.J. The DNA damage response: putting checkpoints in perspective. Nature 2000, 408:433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
38
-
-
0029976325
-
Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
-
Moore J.K., Haber J.E. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 1996, 16:2164-2173.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2164-2173
-
-
Moore, J.K.1
Haber, J.E.2
-
39
-
-
0034195218
-
Partners and pathwaysrepairing a double-strand break
-
Haber J.E. Partners and pathwaysrepairing a double-strand break. Trends Genet. 2000, 16:259-264.
-
(2000)
Trends Genet.
, vol.16
, pp. 259-264
-
-
Haber, J.E.1
-
40
-
-
50649100744
-
Mechanism of eukaryotic homologous recombination
-
San Filippo J., Sung P., Klein H. Mechanism of eukaryotic homologous recombination. Annu. Rev. Biochem. 2008, 77:229-257.
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 229-257
-
-
San Filippo, J.1
Sung, P.2
Klein, H.3
-
41
-
-
0034600975
-
Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
-
Johnson R.D., Jasin M. Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. EMBO J. 2000, 19:3398-3407.
-
(2000)
EMBO J.
, vol.19
, pp. 3398-3407
-
-
Johnson, R.D.1
Jasin, M.2
-
42
-
-
0026709385
-
Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae
-
Kadyk L.C., Hartwell L.H. Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae. Genetics 1992, 132:387-402.
-
(1992)
Genetics
, vol.132
, pp. 387-402
-
-
Kadyk, L.C.1
Hartwell, L.H.2
-
43
-
-
0036864626
-
Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
-
Frank-Vaillant M., Marcand S. Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination. Mol. Cell 2002, 10:1189-1199.
-
(2002)
Mol. Cell
, vol.10
, pp. 1189-1199
-
-
Frank-Vaillant, M.1
Marcand, S.2
-
44
-
-
11244269445
-
The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
-
Aylon Y., Liefshitz B., Kupiec M. The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J. 2004, 23:4868-4875.
-
(2004)
EMBO J.
, vol.23
, pp. 4868-4875
-
-
Aylon, Y.1
Liefshitz, B.2
Kupiec, M.3
-
45
-
-
59249107930
-
Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair
-
Budd M.E., Campbell J.L. Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair. PLoS One 2009, 4:e4267.
-
(2009)
PLoS One
, vol.4
-
-
Budd, M.E.1
Campbell, J.L.2
-
46
-
-
53649104599
-
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
-
Mimitou E.P., Symington L.S. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 2008, 455:770-774.
-
(2008)
Nature
, vol.455
, pp. 770-774
-
-
Mimitou, E.P.1
Symington, L.S.2
-
47
-
-
51549095956
-
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
-
Zhu Z., Chung W.H., Shim E.Y., Lee S.E., Ira G. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 2008, 134:981-994.
-
(2008)
Cell
, vol.134
, pp. 981-994
-
-
Zhu, Z.1
Chung, W.H.2
Shim, E.Y.3
Lee, S.E.4
Ira, G.5
-
48
-
-
77957975815
-
Purified human BRCA2 stimulates RAD51-mediated recombination
-
Jensen R.B., Carreira A., Kowalczykowski S.C. Purified human BRCA2 stimulates RAD51-mediated recombination. Nature 2010, 467:678-683.
-
(2010)
Nature
, vol.467
, pp. 678-683
-
-
Jensen, R.B.1
Carreira, A.2
Kowalczykowski, S.C.3
-
49
-
-
77957804215
-
Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA
-
Liu J., Doty T., Gibson B., Heyer W.D. Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA. Nat. Struct. Mol. Biol. 2010, 17:1260-1262.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1260-1262
-
-
Liu, J.1
Doty, T.2
Gibson, B.3
Heyer, W.D.4
-
50
-
-
0028931265
-
Principles of CDK regulation
-
Morgan D.O. Principles of CDK regulation. Nature 1995, 374:131-134.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
51
-
-
30944457328
-
Inhibition of Aurora A in response to DNA damage
-
Krystyniak A., Garcia-Echeverria C., Prigent C., Ferrari S. Inhibition of Aurora A in response to DNA damage. Oncogene 2006, 25:338-348.
-
(2006)
Oncogene
, vol.25
, pp. 338-348
-
-
Krystyniak, A.1
Garcia-Echeverria, C.2
Prigent, C.3
Ferrari, S.4
-
52
-
-
26444569913
-
Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage
-
Monaco L., Kolthur-Seetharam U., Loury R., Murcia J.M., de Murcia G., Sassone-Corsi P. Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:14244-14248.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 14244-14248
-
-
Monaco, L.1
Kolthur-Seetharam, U.2
Loury, R.3
Murcia, J.M.4
de Murcia, G.5
Sassone-Corsi, P.6
-
53
-
-
0031035528
-
Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation
-
O'Connell M.J., Raleigh J.M., Verkade H.M., Nurse P. Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J. 1997, 16:545-554.
-
(1997)
EMBO J.
, vol.16
, pp. 545-554
-
-
O'Connell, M.J.1
Raleigh, J.M.2
Verkade, H.M.3
Nurse, P.4
-
54
-
-
0034282252
-
Polo-like kinase-1 is a target of the DNA damage checkpoint
-
Smits V.A., Klompmaker R., Arnaud L., Rijksen G., Nigg E.A., Medema R.H. Polo-like kinase-1 is a target of the DNA damage checkpoint. Nat. Cell Biol. 2000, 2:672-676.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 672-676
-
-
Smits, V.A.1
Klompmaker, R.2
Arnaud, L.3
Rijksen, G.4
Nigg, E.A.5
Medema, R.H.6
-
55
-
-
0035834727
-
Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion
-
van Vugt M.A., Smits V.A., Klompmaker R., Medema R.H. Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion. J. Biol. Chem. 2001, 276:41656-41660.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41656-41660
-
-
van Vugt, M.A.1
Smits, V.A.2
Klompmaker, R.3
Medema, R.H.4
-
56
-
-
41149094512
-
Regulation of DNA repair throughout the cell cycle
-
Branzei D., Foiani M. Regulation of DNA repair throughout the cell cycle. Nat. Rev. Mol. Cell Biol. 2008, 9:297-308.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 297-308
-
-
Branzei, D.1
Foiani, M.2
-
57
-
-
0037093318
-
Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III
-
Caspari T., Murray J.M., Carr A.M. Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III. Genes Dev. 2002, 16:1195-1208.
-
(2002)
Genes Dev.
, vol.16
, pp. 1195-1208
-
-
Caspari, T.1
Murray, J.M.2
Carr, A.M.3
-
58
-
-
7244220162
-
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
-
Ira G., Pellicioli A., Balijja A., Wang X., Fiorani S., Carotenuto W., Liberi G., Bressan D., Wan L., Hollingsworth N.M., Haber J.E., Foiani M. DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature 2004, 431:1011-1017.
-
(2004)
Nature
, vol.431
, pp. 1011-1017
-
-
Ira, G.1
Pellicioli, A.2
Balijja, A.3
Wang, X.4
Fiorani, S.5
Carotenuto, W.6
Liberi, G.7
Bressan, D.8
Wan, L.9
Hollingsworth, N.M.10
Haber, J.E.11
Foiani, M.12
-
59
-
-
2942594756
-
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation
-
Baroni E., Viscardi V., Cartagena-Lirola H., Lucchini G., Longhese M.P. The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol. Cell. Biol. 2004, 24:4151-4165.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4151-4165
-
-
Baroni, E.1
Viscardi, V.2
Cartagena-Lirola, H.3
Lucchini, G.4
Longhese, M.P.5
-
60
-
-
53349162987
-
CDK targets Sae2 to control DNA-end resection and homologous recombination
-
Huertas P., Cortes-Ledesma F., Sartori A.A., Aguilera A., Jackson S.P. CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature 2008, 455:689-692.
-
(2008)
Nature
, vol.455
, pp. 689-692
-
-
Huertas, P.1
Cortes-Ledesma, F.2
Sartori, A.A.3
Aguilera, A.4
Jackson, S.P.5
-
61
-
-
33644691699
-
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends
-
Clerici M., Mantiero D., Lucchini G., Longhese M.P. The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends. J. Biol. Chem. 2005, 280:38631-38638.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38631-38638
-
-
Clerici, M.1
Mantiero, D.2
Lucchini, G.3
Longhese, M.P.4
-
62
-
-
0028789631
-
Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast
-
Keeney S., Kleckner N. Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast. Proc. Natl. Acad. Sci. U. S. A. 1995, 92:11274-11278.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 11274-11278
-
-
Keeney, S.1
Kleckner, N.2
-
63
-
-
36248942617
-
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
-
Lengsfeld B.M., Rattray A.J., Bhaskara V., Ghirlando R., Paull T.T. Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Mol. Cell 2007, 28:638-651.
-
(2007)
Mol. Cell
, vol.28
, pp. 638-651
-
-
Lengsfeld, B.M.1
Rattray, A.J.2
Bhaskara, V.3
Ghirlando, R.4
Paull, T.T.5
-
64
-
-
78649805560
-
Mre11-Rad50-Xrs2 and Sae2 promote 5' strand resection of DNA double-strand breaks
-
Nicolette M.L., Lee K., Guo Z., Rani M., Chow J.M., Lee S.E., Paull T.T. Mre11-Rad50-Xrs2 and Sae2 promote 5' strand resection of DNA double-strand breaks. Nat. Struct. Mol. Biol. 2010, 17:1478-1485.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1478-1485
-
-
Nicolette, M.L.1
Lee, K.2
Guo, Z.3
Rani, M.4
Chow, J.M.5
Lee, S.E.6
Paull, T.T.7
-
65
-
-
0030811331
-
Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae
-
Prinz S., Amon A., Klein F. Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. Genetics 1997, 146:781-795.
-
(1997)
Genetics
, vol.146
, pp. 781-795
-
-
Prinz, S.1
Amon, A.2
Klein, F.3
-
66
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori A.A., Lukas C., Coates J., Mistrik M., Fu S., Bartek J., Baer R., Lukas J., Jackson S.P. Human CtIP promotes DNA end resection. Nature 2007, 450:509-514.
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
Bartek, J.6
Baer, R.7
Lukas, J.8
Jackson, S.P.9
-
67
-
-
4444339506
-
Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle
-
Ferreira M.G., Cooper J.P. Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle. Genes Dev. 2004, 18:2249-2254.
-
(2004)
Genes Dev.
, vol.18
, pp. 2249-2254
-
-
Ferreira, M.G.1
Cooper, J.P.2
-
68
-
-
80052492286
-
Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation
-
Chen X., Niu H., Chung W.H., Zhu Z., Papusha A., Shim E.Y., Lee S.E., Sung P., Ira G. Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation. Nat. Struct. Mol. Biol. 2011, 18:1015-1019.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1015-1019
-
-
Chen, X.1
Niu, H.2
Chung, W.H.3
Zhu, Z.4
Papusha, A.5
Shim, E.Y.6
Lee, S.E.7
Sung, P.8
Ira, G.9
-
69
-
-
0025365192
-
Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells
-
Din S., Brill S.J., Fairman M.P., Stillman B. Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells. Genes Dev. 1990, 4:968-977.
-
(1990)
Genes Dev.
, vol.4
, pp. 968-977
-
-
Din, S.1
Brill, S.J.2
Fairman, M.P.3
Stillman, B.4
-
70
-
-
0033179985
-
Cdc2 phosphorylation of Crb2 is required for reestablishing cell cycle progression after the damage checkpoint
-
Esashi F., Yanagida M. Cdc2 phosphorylation of Crb2 is required for reestablishing cell cycle progression after the damage checkpoint. Mol. Cell 1999, 4:167-174.
-
(1999)
Mol. Cell
, vol.4
, pp. 167-174
-
-
Esashi, F.1
Yanagida, M.2
-
71
-
-
77957368466
-
Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity
-
Granata M., Lazzaro F., Novarina D., Panigada D., Puddu F., Abreu C.M., Kumar R., Grenon M., Lowndes N.F., Plevani P., Muzi-Falconi M. Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity. PLoS Genet. 2010, 6.
-
(2010)
PLoS Genet.
, vol.6
-
-
Granata, M.1
Lazzaro, F.2
Novarina, D.3
Panigada, D.4
Puddu, F.5
Abreu, C.M.6
Kumar, R.7
Grenon, M.8
Lowndes, N.F.9
Plevani, P.10
Muzi-Falconi, M.11
-
72
-
-
0031466305
-
Cyclin-dependent kinases: engines, clocks, and microprocessors
-
Morgan D.O. Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell Dev. Biol. 1997, 13:261-291.
-
(1997)
Annu. Rev. Cell Dev. Biol.
, vol.13
, pp. 261-291
-
-
Morgan, D.O.1
-
73
-
-
0035235736
-
Mitotic kinases as regulators of cell division and its checkpoints
-
Nigg E.A. Mitotic kinases as regulators of cell division and its checkpoints. Nat. Rev. Mol. Cell Biol. 2001, 2:21-32.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 21-32
-
-
Nigg, E.A.1
-
74
-
-
74049119311
-
Overall Cdk activity modulates the DNA damage response in mammalian cells
-
Cerqueira A., Santamaria D., Martinez-Pastor B., Cuadrado M., Fernandez-Capetillo O., Barbacid M. Overall Cdk activity modulates the DNA damage response in mammalian cells. J. Cell Biol. 2009, 187:773-780.
-
(2009)
J. Cell Biol.
, vol.187
, pp. 773-780
-
-
Cerqueira, A.1
Santamaria, D.2
Martinez-Pastor, B.3
Cuadrado, M.4
Fernandez-Capetillo, O.5
Barbacid, M.6
-
75
-
-
66149114020
-
Human CtIP mediates cell cycle control of DNA end resection and double strand break repair
-
Huertas P., Jackson S.P. Human CtIP mediates cell cycle control of DNA end resection and double strand break repair. J. Biol. Chem. 2009, 284:9558-9565.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 9558-9565
-
-
Huertas, P.1
Jackson, S.P.2
-
76
-
-
84856747932
-
Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2
-
Buis J., Stoneham T., Spehalski E., Ferguson D.O. Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2. Nat. Struct. Mol. Biol. 2012, 19:246-252.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 246-252
-
-
Buis, J.1
Stoneham, T.2
Spehalski, E.3
Ferguson, D.O.4
-
77
-
-
84883599853
-
Prolyl Isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection
-
Steger M., Murina O., Huhn D., Ferretti L.P., Walser R., Hanggi K., Lafranchi L., Neugebauer C., Paliwal S., Janscak P., Gerrits B., Del Sal G., Zerbe O., Sartori A.A. Prolyl Isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection. Mol. Cell 2013, 50:333-343.
-
(2013)
Mol. Cell
, vol.50
, pp. 333-343
-
-
Steger, M.1
Murina, O.2
Huhn, D.3
Ferretti, L.P.4
Walser, R.5
Hanggi, K.6
Lafranchi, L.7
Neugebauer, C.8
Paliwal, S.9
Janscak, P.10
Gerrits, B.11
Del Sal, G.12
Zerbe, O.13
Sartori, A.A.14
-
78
-
-
84861843272
-
CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination
-
Falck J., Forment J.V., Coates J., Mistrik M., Lukas J., Bartek J., Jackson S.P. CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination. EMBO Rep. 2012, 13:561-568.
-
(2012)
EMBO Rep.
, vol.13
, pp. 561-568
-
-
Falck, J.1
Forment, J.V.2
Coates, J.3
Mistrik, M.4
Lukas, J.5
Bartek, J.6
Jackson, S.P.7
-
79
-
-
79960150694
-
Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition
-
Johnson N., Li Y.C., Walton Z.E., Cheng K.A., Li D., Rodig S.J., Moreau L.A., Unitt C., Bronson R.T., Thomas H.D., Newell D.R., D'Andrea A.D., Curtin N.J., Wong K.K., Shapiro G.I. Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition. Nat. Med. 2011, 17:875-882.
-
(2011)
Nat. Med.
, vol.17
, pp. 875-882
-
-
Johnson, N.1
Li, Y.C.2
Walton, Z.E.3
Cheng, K.A.4
Li, D.5
Rodig, S.J.6
Moreau, L.A.7
Unitt, C.8
Bronson, R.T.9
Thomas, H.D.10
Newell, D.R.11
D'Andrea, A.D.12
Curtin, N.J.13
Wong, K.K.14
Shapiro, G.I.15
-
80
-
-
79958254560
-
A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers
-
Jirawatnotai S., Hu Y., Michowski W., Elias J.E., Becks L., Bienvenu F., Zagozdzon A., Goswami T., Wang Y.E., Clark A.B., Kunkel T.A., van Harn T., Xia B., Correll M., Quackenbush J., Livingston D.M., Gygi S.P., Sicinski P. A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers. Nature 2011, 474:230-234.
-
(2011)
Nature
, vol.474
, pp. 230-234
-
-
Jirawatnotai, S.1
Hu, Y.2
Michowski, W.3
Elias, J.E.4
Becks, L.5
Bienvenu, F.6
Zagozdzon, A.7
Goswami, T.8
Wang, Y.E.9
Clark, A.B.10
Kunkel, T.A.11
van Harn, T.12
Xia, B.13
Correll, M.14
Quackenbush, J.15
Livingston, D.M.16
Gygi, S.P.17
Sicinski, P.18
-
81
-
-
81055137333
-
A quantitative model for ordered Cdk substrate dephosphorylation during mitotic exit
-
Bouchoux C., Uhlmann F. A quantitative model for ordered Cdk substrate dephosphorylation during mitotic exit. Cell 2011, 147:803-814.
-
(2011)
Cell
, vol.147
, pp. 803-814
-
-
Bouchoux, C.1
Uhlmann, F.2
-
82
-
-
0000632574
-
Irradiation of parts of individual cells
-
Zirkle R.E., Bloom W. Irradiation of parts of individual cells. Science 1953, 117:487-493.
-
(1953)
Science
, vol.117
, pp. 487-493
-
-
Zirkle, R.E.1
Bloom, W.2
-
83
-
-
0032563638
-
Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase
-
Rieder C.L., Cole R.W. Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase. J. Cell Biol. 1998, 142:1013-1022.
-
(1998)
J. Cell Biol.
, vol.142
, pp. 1013-1022
-
-
Rieder, C.L.1
Cole, R.W.2
-
84
-
-
0037195281
-
DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint
-
Mikhailov A., Cole R.W., Rieder C.L. DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint. Curr. Biol. 2002, 12:1797-1806.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1797-1806
-
-
Mikhailov, A.1
Cole, R.W.2
Rieder, C.L.3
-
85
-
-
3242888393
-
Chromosome damage and progression into and through mitosis in vertebrates
-
Morrison C., Rieder C.L. Chromosome damage and progression into and through mitosis in vertebrates. DNA Repair (Amst) 2004, 3:1133-1139.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1133-1139
-
-
Morrison, C.1
Rieder, C.L.2
-
86
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou E.P., Boon C., Redon C., Bonner W.M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 1999, 146:905-916.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
87
-
-
4444321565
-
Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells
-
van Vugt M.A., Bras A., Medema R.H. Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells. Mol. Cell 2004, 15:799-811.
-
(2004)
Mol. Cell
, vol.15
, pp. 799-811
-
-
van Vugt, M.A.1
Bras, A.2
Medema, R.H.3
-
88
-
-
23844525856
-
Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways
-
Watanabe N., Arai H., Iwasaki J., Shiina M., Ogata K., Hunter T., Osada H. Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:11663-11668.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 11663-11668
-
-
Watanabe, N.1
Arai, H.2
Iwasaki, J.3
Shiina, M.4
Ogata, K.5
Hunter, T.6
Osada, H.7
-
89
-
-
1842428734
-
M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP
-
Watanabe N., Arai H., Nishihara Y., Taniguchi M., Hunter T., Osada H. M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:4419-4424.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 4419-4424
-
-
Watanabe, N.1
Arai, H.2
Nishihara, Y.3
Taniguchi, M.4
Hunter, T.5
Osada, H.6
-
90
-
-
33947304756
-
Substrate competition as a source of ultrasensitivity in the inactivation of Wee1
-
Kim S.Y., Ferrell J.E. Substrate competition as a source of ultrasensitivity in the inactivation of Wee1. Cell 2007, 128:1133-1145.
-
(2007)
Cell
, vol.128
, pp. 1133-1145
-
-
Kim, S.Y.1
Ferrell, J.E.2
-
91
-
-
0037418836
-
Tome-1 a trigger of mitotic entry, is degraded during G1 via the APC
-
Ayad N.G., Rankin S., Murakami M., Jebanathirajah J., Gygi S., Kirschner M.W. Tome-1 a trigger of mitotic entry, is degraded during G1 via the APC. Cell 2003, 113:101-113.
-
(2003)
Cell
, vol.113
, pp. 101-113
-
-
Ayad, N.G.1
Rankin, S.2
Murakami, M.3
Jebanathirajah, J.4
Gygi, S.5
Kirschner, M.W.6
-
92
-
-
37249063516
-
Redundant ubiquitin ligase activities regulate wee1 degradation and mitotic entry
-
Smith A., Simanski S., Fallahi M., Ayad N.G. Redundant ubiquitin ligase activities regulate wee1 degradation and mitotic entry. Cell Cycle 2007, 6:2795-2799.
-
(2007)
Cell Cycle
, vol.6
, pp. 2795-2799
-
-
Smith, A.1
Simanski, S.2
Fallahi, M.3
Ayad, N.G.4
-
93
-
-
16344386249
-
The Polo-like kinase Plx1 interacts with and inhibits Myt1 after fertilization of Xenopus eggs
-
Inoue D., Sagata N. The Polo-like kinase Plx1 interacts with and inhibits Myt1 after fertilization of Xenopus eggs. EMBO J. 2005, 24:1057-1067.
-
(2005)
EMBO J.
, vol.24
, pp. 1057-1067
-
-
Inoue, D.1
Sagata, N.2
-
94
-
-
0038492408
-
Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate
-
Nakajima H., Toyoshima-Morimoto F., Taniguchi E., Nishida E. Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate. J. Biol. Chem. 2003, 278:25277-25280.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25277-25280
-
-
Nakajima, H.1
Toyoshima-Morimoto, F.2
Taniguchi, E.3
Nishida, E.4
-
95
-
-
77951146213
-
A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry
-
Ruiz E.J., Vilar M., Nebreda A.R. A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry. Curr. Biol. 2010, 20:717-723.
-
(2010)
Curr. Biol.
, vol.20
, pp. 717-723
-
-
Ruiz, E.J.1
Vilar, M.2
Nebreda, A.R.3
-
96
-
-
0033634679
-
Claspin a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts
-
Kumagai A., Dunphy W.G., Claspin a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol. Cell 2000, 6:839-849.
-
(2000)
Mol. Cell
, vol.6
, pp. 839-849
-
-
Kumagai, A.1
Dunphy, W.G.2
-
97
-
-
33746429958
-
Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress
-
Mailand N., Bekker-Jensen S., Bartek J., Lukas J. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress. Mol. Cell 2006, 23:307-318.
-
(2006)
Mol. Cell
, vol.23
, pp. 307-318
-
-
Mailand, N.1
Bekker-Jensen, S.2
Bartek, J.3
Lukas, J.4
-
98
-
-
33749246225
-
Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery
-
Mamely I., van Vugt M.A., Smits V.A., Semple J.I., Lemmens B., Perrakis A., Medema R.H., Freire R. Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Curr. Biol. 2006, 16:1950-1955.
-
(2006)
Curr. Biol.
, vol.16
, pp. 1950-1955
-
-
Mamely, I.1
van Vugt, M.A.2
Smits, V.A.3
Semple, J.I.4
Lemmens, B.5
Perrakis, A.6
Medema, R.H.7
Freire, R.8
-
99
-
-
33746413746
-
SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response
-
Peschiaroli A., Dorrello N.V., Guardavaccaro D., Venere M., Halazonetis T., Sherman N.E., Pagano M. SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol. Cell 2006, 23:319-329.
-
(2006)
Mol. Cell
, vol.23
, pp. 319-329
-
-
Peschiaroli, A.1
Dorrello, N.V.2
Guardavaccaro, D.3
Venere, M.4
Halazonetis, T.5
Sherman, N.E.6
Pagano, M.7
-
100
-
-
2542459341
-
Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase
-
Yoo H.Y., Kumagai A., Shevchenko A., Dunphy W.G. Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase. Cell 2004, 117:575-588.
-
(2004)
Cell
, vol.117
, pp. 575-588
-
-
Yoo, H.Y.1
Kumagai, A.2
Shevchenko, A.3
Dunphy, W.G.4
-
101
-
-
75749130721
-
A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint
-
van Vugt M.A., Gardino A.K., Linding R., Ostheimer G.J., Reinhardt H.C., Ong S.E., Tan C.S., Miao H., Keezer S.M., Li J., Pawson T., Lewis T.A., Carr S.A., Smerdon S.J., Brummelkamp T.R., Yaffe M.B. A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint. PLoS Biol. 2010, 8:e1000287.
-
(2010)
PLoS Biol.
, vol.8
-
-
van Vugt, M.A.1
Gardino, A.K.2
Linding, R.3
Ostheimer, G.J.4
Reinhardt, H.C.5
Ong, S.E.6
Tan, C.S.7
Miao, H.8
Keezer, S.M.9
Li, J.10
Pawson, T.11
Lewis, T.A.12
Carr, S.A.13
Smerdon, S.J.14
Brummelkamp, T.R.15
Yaffe, M.B.16
-
102
-
-
0037112212
-
53BP1, a mediator of the DNA damage checkpoint
-
Wang B., Matsuoka S., Carpenter P.B., Elledge S.J. 53BP1, a mediator of the DNA damage checkpoint. Science 2002, 298:1435-1438.
-
(2002)
Science
, vol.298
, pp. 1435-1438
-
-
Wang, B.1
Matsuoka, S.2
Carpenter, P.B.3
Elledge, S.J.4
-
103
-
-
0037378527
-
P53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice
-
Ward I.M., Minn K., van Deursen J., Chen J. p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice. Mol. Cell. Biol. 2003, 23:2556-2563.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2556-2563
-
-
Ward, I.M.1
Minn, K.2
van Deursen, J.3
Chen, J.4
-
104
-
-
77954997032
-
DNA damage signaling in response to double-strand breaks during mitosis
-
Giunta S., Belotserkovskaya R., Jackson S.P. DNA damage signaling in response to double-strand breaks during mitosis. J. Cell Biol. 2010, 190:197-207.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 197-207
-
-
Giunta, S.1
Belotserkovskaya, R.2
Jackson, S.P.3
-
105
-
-
74949108644
-
The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks
-
Nakamura A.J., Rao V.A., Pommier Y., Bonner W.M. The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks. Cell Cycle 2010, 9:389-397.
-
(2010)
Cell Cycle
, vol.9
, pp. 389-397
-
-
Nakamura, A.J.1
Rao, V.A.2
Pommier, Y.3
Bonner, W.M.4
-
106
-
-
70350222196
-
DNA damage foci in mitosis are devoid of 53BP1
-
Nelson G., Buhmann M., von Zglinicki T. DNA damage foci in mitosis are devoid of 53BP1. Cell Cycle 2009, 8:3379-3383.
-
(2009)
Cell Cycle
, vol.8
, pp. 3379-3383
-
-
Nelson, G.1
Buhmann, M.2
von Zglinicki, T.3
-
107
-
-
0037804567
-
Dual phosphorylation controls Cdc25 phosphatases and mitotic entry
-
Bulavin D.V., Higashimoto Y., Demidenko Z.N., Meek S., Graves P., Phillips C., Zhao H., Moody S.A., Appella E., Piwnica-Worms H., Fornace A.J. Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat. Cell Biol. 2003, 5:545-551.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 545-551
-
-
Bulavin, D.V.1
Higashimoto, Y.2
Demidenko, Z.N.3
Meek, S.4
Graves, P.5
Phillips, C.6
Zhao, H.7
Moody, S.A.8
Appella, E.9
Piwnica-Worms, H.10
Fornace, A.J.11
-
108
-
-
77953570936
-
Cell cycle re-entry mechanisms after DNA damage checkpoints: giving it some gas to shut off the breaks!
-
van Vugt M.A., Yaffe M.B. Cell cycle re-entry mechanisms after DNA damage checkpoints: giving it some gas to shut off the breaks!. Cell Cycle 2010, 9:2097-2101.
-
(2010)
Cell Cycle
, vol.9
, pp. 2097-2101
-
-
van Vugt, M.A.1
Yaffe, M.B.2
-
109
-
-
0035881727
-
Suppression of cap-dependent translation in mitosis
-
Pyronnet S., Dostie J., Sonenberg N. Suppression of cap-dependent translation in mitosis. Genes Dev. 2001, 15:2083-2093.
-
(2001)
Genes Dev.
, vol.15
, pp. 2083-2093
-
-
Pyronnet, S.1
Dostie, J.2
Sonenberg, N.3
-
110
-
-
33947236863
-
14-3-3sigma controls mitotic translation to facilitate cytokinesis
-
Wilker E.W., van Vugt M.A., Artim S.A., Huang P.H., Petersen C.P., Reinhardt H.C., Feng Y., Sharp P.A., Sonenberg N., White F.M., Yaffe M.B. 14-3-3sigma controls mitotic translation to facilitate cytokinesis. Nature 2007, 446:329-332.
-
(2007)
Nature
, vol.446
, pp. 329-332
-
-
Wilker, E.W.1
van Vugt, M.A.2
Artim, S.A.3
Huang, P.H.4
Petersen, C.P.5
Reinhardt, H.C.6
Feng, Y.7
Sharp, P.A.8
Sonenberg, N.9
White, F.M.10
Yaffe, M.B.11
-
111
-
-
84855391980
-
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction
-
Orth J.D., Loewer A., Lahav G., Mitchison T.J. Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction. Mol. Biol. Cell 2012, 23:567-576.
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 567-576
-
-
Orth, J.D.1
Loewer, A.2
Lahav, G.3
Mitchison, T.J.4
-
112
-
-
33645524978
-
Two internal ribosome entry sites mediate the translation of p53 isoforms
-
Ray P.S., Grover R., Das S. Two internal ribosome entry sites mediate the translation of p53 isoforms. EMBO Rep. 2006, 7:404-410.
-
(2006)
EMBO Rep.
, vol.7
, pp. 404-410
-
-
Ray, P.S.1
Grover, R.2
Das, S.3
-
113
-
-
33746855405
-
The identification of an internal ribosomal entry site in the 5'-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage
-
Yang D.Q., Halaby M.J., Zhang Y. The identification of an internal ribosomal entry site in the 5'-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage. Oncogene 2006, 25:4613-4619.
-
(2006)
Oncogene
, vol.25
, pp. 4613-4619
-
-
Yang, D.Q.1
Halaby, M.J.2
Zhang, Y.3
-
114
-
-
80052609660
-
Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair
-
Peterson S.E., Li Y., Chait B.T., Gottesman M.E., Baer R., Gautier J. Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair. J. Cell Biol. 2011, 194:705-720.
-
(2011)
J. Cell Biol.
, vol.194
, pp. 705-720
-
-
Peterson, S.E.1
Li, Y.2
Chait, B.T.3
Gottesman, M.E.4
Baer, R.5
Gautier, J.6
-
115
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki M., Clapperton J.A., Mohammad D., Yaffe M.B., Smerdon S.J., Jackson S.P. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 2005, 123:1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
116
-
-
78650431603
-
Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation
-
Gomez-Godinez V., Wu T., Sherman A.J., Lee C.S., Liaw L.H., Zhongsheng Y., Yokomori K., Berns M.W. Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation. Nucleic Acids Res. 2010, 38:e202.
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Gomez-Godinez, V.1
Wu, T.2
Sherman, A.J.3
Lee, C.S.4
Liaw, L.H.5
Zhongsheng, Y.6
Yokomori, K.7
Berns, M.W.8
-
117
-
-
33845484385
-
Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4
-
Mari P.O., Florea B.I., Persengiev S.P., Verkaik N.S., Bruggenwirth H.T., Modesti M., Giglia-Mari G., Bezstarosti K., Demmers J.A., Luider T.M., Houtsmuller A.B., van Gent D.C. Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:18597-18602.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 18597-18602
-
-
Mari, P.O.1
Florea, B.I.2
Persengiev, S.P.3
Verkaik, N.S.4
Bruggenwirth, H.T.5
Modesti, M.6
Giglia-Mari, G.7
Bezstarosti, K.8
Demmers, J.A.9
Luider, T.M.10
Houtsmuller, A.B.11
van Gent, D.C.12
-
118
-
-
84856776536
-
Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair
-
Yata K., Lloyd J., Maslen S., Bleuyard J.Y., Skehel M., Smerdon S.J., Esashi F. Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair. Mol. Cell 2012, 45:371-383.
-
(2012)
Mol. Cell
, vol.45
, pp. 371-383
-
-
Yata, K.1
Lloyd, J.2
Maslen, S.3
Bleuyard, J.Y.4
Skehel, M.5
Smerdon, S.J.6
Esashi, F.7
-
119
-
-
15844373362
-
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
-
Esashi F., Christ N., Gannon J., Liu Y., Hunt T., Jasin M., West S.C. CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature 2005, 434:598-604.
-
(2005)
Nature
, vol.434
, pp. 598-604
-
-
Esashi, F.1
Christ, N.2
Gannon, J.3
Liu, Y.4
Hunt, T.5
Jasin, M.6
West, S.C.7
-
120
-
-
67649881097
-
The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry
-
Ayoub N., Rajendra E., Su X., Jeyasekharan A.D., Mahen R., Venkitaraman A.R. The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry. Curr. Biol. 2009, 19:1075-1085.
-
(2009)
Curr. Biol.
, vol.19
, pp. 1075-1085
-
-
Ayoub, N.1
Rajendra, E.2
Su, X.3
Jeyasekharan, A.D.4
Mahen, R.5
Venkitaraman, A.R.6
-
121
-
-
84879416168
-
Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination
-
Krajewska M., Heijink A.M., Bisselink Y.J., Seinstra R.I., Sillje H.H., de Vries E.G., van Vugt M.A. Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination. Oncogene 2012, 32:3001-3008.
-
(2012)
Oncogene
, vol.32
, pp. 3001-3008
-
-
Krajewska, M.1
Heijink, A.M.2
Bisselink, Y.J.3
Seinstra, R.I.4
Sillje, H.H.5
de Vries, E.G.6
van Vugt, M.A.7
-
122
-
-
77957219796
-
Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis
-
Uetake Y., Sluder G. Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis. Curr. Biol. 2010, 20:1666-1671.
-
(2010)
Curr. Biol.
, vol.20
, pp. 1666-1671
-
-
Uetake, Y.1
Sluder, G.2
-
123
-
-
37549010631
-
Human cancer cells commonly acquire DNA damage during mitotic arrest
-
Dalton W.B., Nandan M.O., Moore R.T., Yang V.W. Human cancer cells commonly acquire DNA damage during mitotic arrest. Cancer Res. 2007, 67:11487-11492.
-
(2007)
Cancer Res.
, vol.67
, pp. 11487-11492
-
-
Dalton, W.B.1
Nandan, M.O.2
Moore, R.T.3
Yang, V.W.4
-
124
-
-
84872026180
-
Linking abnormal mitosis to the acquisition of DNA damage
-
Ganem N.J., Pellman D. Linking abnormal mitosis to the acquisition of DNA damage. J. Cell Biol. 2012, 199:871-881.
-
(2012)
J. Cell Biol.
, vol.199
, pp. 871-881
-
-
Ganem, N.J.1
Pellman, D.2
-
126
-
-
0031813288
-
Colonic epithelial cell proliferation in hereditary non-polyposis colorectal cancer
-
Green S.E., Chapman P., Burn J., Burt A.D., Bennett M., Appleton D.R., Varma J.S., Mathers J.C. Colonic epithelial cell proliferation in hereditary non-polyposis colorectal cancer. Gut 1998, 43:85-92.
-
(1998)
Gut
, vol.43
, pp. 85-92
-
-
Green, S.E.1
Chapman, P.2
Burn, J.3
Burt, A.D.4
Bennett, M.5
Appleton, D.R.6
Varma, J.S.7
Mathers, J.C.8
-
127
-
-
0000805753
-
Mitotic indices of human bone marrow cells. I. Number and cytologic distribution of mitoses
-
Killmann S.A., Cronkite E.P., Fliedner T.M., Bond V.P. Mitotic indices of human bone marrow cells. I. Number and cytologic distribution of mitoses. Blood 1962, 19:743-750.
-
(1962)
Blood
, vol.19
, pp. 743-750
-
-
Killmann, S.A.1
Cronkite, E.P.2
Fliedner, T.M.3
Bond, V.P.4
-
128
-
-
33947204449
-
Chromosome breakage after G2 checkpoint release
-
Deckbar D., Birraux J., Krempler A., Tchouandong L., Beucher A., Walker S., Stiff T., Jeggo P., Lobrich M. Chromosome breakage after G2 checkpoint release. J. Cell Biol. 2007, 176:749-755.
-
(2007)
J. Cell Biol.
, vol.176
, pp. 749-755
-
-
Deckbar, D.1
Birraux, J.2
Krempler, A.3
Tchouandong, L.4
Beucher, A.5
Walker, S.6
Stiff, T.7
Jeggo, P.8
Lobrich, M.9
-
129
-
-
34548223252
-
An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells
-
Krempler A., Deckbar D., Jeggo P.A., Lobrich M. An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells. Cell Cycle 2007, 6:1682-1686.
-
(2007)
Cell Cycle
, vol.6
, pp. 1682-1686
-
-
Krempler, A.1
Deckbar, D.2
Jeggo, P.A.3
Lobrich, M.4
-
130
-
-
84876333995
-
Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates
-
Neelsen K.J., Zanini I.M., Herrador R., Lopes M. Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates. J. Cell Biol. 2013, 200:699-708.
-
(2013)
J. Cell Biol.
, vol.200
, pp. 699-708
-
-
Neelsen, K.J.1
Zanini, I.M.2
Herrador, R.3
Lopes, M.4
-
131
-
-
0032146974
-
The vertebrate cell kinetochore and its roles during mitosis
-
Rieder C.L., Salmon E.D. The vertebrate cell kinetochore and its roles during mitosis. Trends Cell Biol. 1998, 8:310-318.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 310-318
-
-
Rieder, C.L.1
Salmon, E.D.2
-
132
-
-
79952281751
-
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
-
Lukas C., Savic V., Bekker-Jensen S., Doil C., Neumann B., Pedersen R.S., Grofte M., Chan K.L., Hickson I.D., Bartek J., Lukas J. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nat. Cell Biol. 2011, 13:243-253.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 243-253
-
-
Lukas, C.1
Savic, V.2
Bekker-Jensen, S.3
Doil, C.4
Neumann, B.5
Pedersen, R.S.6
Grofte, M.7
Chan, K.L.8
Hickson, I.D.9
Bartek, J.10
Lukas, J.11
-
133
-
-
76749157172
-
Mad2 prolongs DNA damage checkpoint arrest caused by a double-strand break via a centromere-dependent mechanism
-
Dotiwala F., Harrison J.C., Jain S., Sugawara N., Haber J.E. Mad2 prolongs DNA damage checkpoint arrest caused by a double-strand break via a centromere-dependent mechanism. Curr. Biol. 2010, 20:328-332.
-
(2010)
Curr. Biol.
, vol.20
, pp. 328-332
-
-
Dotiwala, F.1
Harrison, J.C.2
Jain, S.3
Sugawara, N.4
Haber, J.E.5
-
134
-
-
4444245817
-
Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents
-
Nitta M., Kobayashi O., Honda S., Hirota T., Kuninaka S., Marumoto T., Ushio Y., Saya H. Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents. Oncogene 2004, 23:6548-6558.
-
(2004)
Oncogene
, vol.23
, pp. 6548-6558
-
-
Nitta, M.1
Kobayashi, O.2
Honda, S.3
Hirota, T.4
Kuninaka, S.5
Marumoto, T.6
Ushio, Y.7
Saya, H.8
-
135
-
-
48449098623
-
Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
-
Gascoigne K.E., Taylor S.S. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008, 14:111-122.
-
(2008)
Cancer Cell
, vol.14
, pp. 111-122
-
-
Gascoigne, K.E.1
Taylor, S.S.2
-
136
-
-
33744996707
-
Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
-
Brito D.A., Rieder C.L. Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint. Curr. Biol. 2006, 16:1194-1200.
-
(2006)
Curr. Biol.
, vol.16
, pp. 1194-1200
-
-
Brito, D.A.1
Rieder, C.L.2
-
137
-
-
22244459880
-
Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage
-
Tao W., South V.J., Zhang Y., Davide J.P., Farrell L., Kohl N.E., Sepp-Lorenzino L., Lobell R.B. Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage. Cancer Cell 2005, 8:49-59.
-
(2005)
Cancer Cell
, vol.8
, pp. 49-59
-
-
Tao, W.1
South, V.J.2
Zhang, Y.3
Davide, J.P.4
Farrell, L.5
Kohl, N.E.6
Sepp-Lorenzino, L.7
Lobell, R.B.8
-
138
-
-
3042537050
-
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy
-
Castedo M., Perfettini J.L., Roumier T., Valent A., Raslova H., Yakushijin K., Horne D., Feunteun J., Lenoir G., Medema R., Vainchenker W., Kroemer G. Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy. Oncogene 2004, 23:4362-4370.
-
(2004)
Oncogene
, vol.23
, pp. 4362-4370
-
-
Castedo, M.1
Perfettini, J.L.2
Roumier, T.3
Valent, A.4
Raslova, H.5
Yakushijin, K.6
Horne, D.7
Feunteun, J.8
Lenoir, G.9
Medema, R.10
Vainchenker, W.11
Kroemer, G.12
-
139
-
-
84856424908
-
DNA breaks and chromosome pulverization from errors in mitosis
-
Crasta K., Ganem N.J., Dagher R., Lantermann A.B., Ivanova E.V., Pan Y., Nezi L., Protopopov A., Chowdhury D., Pellman D. DNA breaks and chromosome pulverization from errors in mitosis. Nature 2012, 482:53-58.
-
(2012)
Nature
, vol.482
, pp. 53-58
-
-
Crasta, K.1
Ganem, N.J.2
Dagher, R.3
Lantermann, A.B.4
Ivanova, E.V.5
Pan, Y.6
Nezi, L.7
Protopopov, A.8
Chowdhury, D.9
Pellman, D.10
-
140
-
-
33645284756
-
Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms
-
Mansilla S., Priebe W., Portugal J. Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms. Cell Cycle 2006, 5:53-60.
-
(2006)
Cell Cycle
, vol.5
, pp. 53-60
-
-
Mansilla, S.1
Priebe, W.2
Portugal, J.3
-
141
-
-
80053364894
-
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations
-
Janssen A., van der Burg M., Szuhai K., Kops G.J., Medema R.H. Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science 2011, 333:1895-1898.
-
(2011)
Science
, vol.333
, pp. 1895-1898
-
-
Janssen, A.1
van der Burg, M.2
Szuhai, K.3
Kops, G.J.4
Medema, R.H.5
-
142
-
-
80051871652
-
Aneuploidy drives genomic instability in yeast
-
Sheltzer J.M., Blank H.M., Pfau S.J., Tange Y., George B.M., Humpton T.J., Brito I.L., Hiraoka Y., Niwa O., Amon A. Aneuploidy drives genomic instability in yeast. Science 2011, 333:1026-1030.
-
(2011)
Science
, vol.333
, pp. 1026-1030
-
-
Sheltzer, J.M.1
Blank, H.M.2
Pfau, S.J.3
Tange, Y.4
George, B.M.5
Humpton, T.J.6
Brito, I.L.7
Hiraoka, Y.8
Niwa, O.9
Amon, A.10
-
143
-
-
84874362586
-
Replication stress links structural and numerical cancer chromosomal instability
-
Burrell R.A., McClelland S.E., Endesfelder D., Groth P., Weller M.C., Shaikh N., Domingo E., Kanu N., Dewhurst S.M., Gronroos E., Chew S.K., Rowan A.J., Schenk A., Sheffer M., Howell M., Kschischo M., Behrens A., Helleday T., Bartek J., Tomlinson I.P., Swanton C. Replication stress links structural and numerical cancer chromosomal instability. Nature 2013, 494:492-496.
-
(2013)
Nature
, vol.494
, pp. 492-496
-
-
Burrell, R.A.1
McClelland, S.E.2
Endesfelder, D.3
Groth, P.4
Weller, M.C.5
Shaikh, N.6
Domingo, E.7
Kanu, N.8
Dewhurst, S.M.9
Gronroos, E.10
Chew, S.K.11
Rowan, A.J.12
Schenk, A.13
Sheffer, M.14
Howell, M.15
Kschischo, M.16
Behrens, A.17
Helleday, T.18
Bartek, J.19
Tomlinson, I.P.20
Swanton, C.21
more..
-
144
-
-
79955490586
-
Replication stress induces 53BP1-containing OPT domains in G1 cells
-
Harrigan J.A., Belotserkovskaya R., Coates J., Dimitrova D.S., Polo S.E., Bradshaw C.R., Fraser P., Jackson S.P. Replication stress induces 53BP1-containing OPT domains in G1 cells. J. Cell Biol. 2011, 193:97-108.
-
(2011)
J. Cell Biol.
, vol.193
, pp. 97-108
-
-
Harrigan, J.A.1
Belotserkovskaya, R.2
Coates, J.3
Dimitrova, D.S.4
Polo, S.E.5
Bradshaw, C.R.6
Fraser, P.7
Jackson, S.P.8
-
145
-
-
35948952747
-
Base excision repair of ionizing radiation-induced DNA damage in G1 and G2 cell cycle phases
-
Chaudhry M.A. Base excision repair of ionizing radiation-induced DNA damage in G1 and G2 cell cycle phases. Cancer Cell Int. 2007, 7:15.
-
(2007)
Cancer Cell Int.
, vol.7
, pp. 15
-
-
Chaudhry, M.A.1
-
146
-
-
33845979430
-
The cell cycle and DNA mismatch repair
-
Schroering A.G., Edelbrock M.A., Richards T.J., Williams K.J. The cell cycle and DNA mismatch repair. Exp. Cell Res. 2007, 313:292-304.
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 292-304
-
-
Schroering, A.G.1
Edelbrock, M.A.2
Richards, T.J.3
Williams, K.J.4
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