Rapid destruction of human Cdc25A in response to DNA damage

Science

Volumn 288, Issue 5470, 2000, Pages 1425-1429

  Mailand, Niels ^a   Falck, Jacob ^a   Lukas, Claudia ^a   Syljuåsen, Randi G ^a   Welcker, Markus ^a   Bartek, Jiri ^a   Lukas, Jiri ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATASE; PROTEASOME; PROTEIN KINASE; PROTEIN P53; UBIQUITIN;

ARTICLE; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENOTOXICITY; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

CDC2-CDC28 KINASES; CDC25 PHOSPHATASE; CELL LINE; CELL SURVIVAL; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; CYSTEINE ENDOPEPTIDASES; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; G1 PHASE; HUMANS; MULTIENZYME COMPLEXES; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; S PHASE; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EUKARYOTA;

EID: 0034717309     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.288.5470.1425     Document Type: Article

References (19)

1. L. H. Hartwell and M. B. Kastan, Science 266, 1821 (1994);
2. S. J. Elledge, Science 274, 1664 (1996);
3. K. Nasmyth, Science 274, 1643 (1996);
4. T. Weinert, Cell 94, 555 (1998).
5. L. J. Ko and C. Prives, Genes Dev. 10, 1054 (1996);
6. A. J. Levine, Cell 88, 323 (1997);
7. C. Lengauer. K. W. Kinzler, B. Vogelstein, Nature 396, 643 (1998).
8. J. A. D'Anna, J. G. Valdez, R. C. Habbersett, H. A. Crissman, Radiat. Res. 148, 260 (1997);
9. H. Lee, J. M. Larner, J. L. Hamlin, Proc. Natl. Acad. Sci. U.S.A. 94, 526 (1997);
10. G. Xie et al., Oncogene 16, 721 (1998).
11. J. Brugarolas et al., Nature 377, 552 (1995);
12. C. Deng, P. Zhang, J. W. Harper. S. J. Elledge, P. Leder. Cell 82, 675 (1995).
13. B. Furnari, N. Rhind, P. Russell, Science 277, 1495 (1997);
14. C. Y. Peng et al., Science 277, 1501 (1997);
15. Y. Sanchez et al., Science 277, 1497 (1997);
16. T. Weinert, Science 277, 1450 (1997).
17. S. Jinno et al., EMBO J. 13, 1549 (1994);
18. I. Hoffmann, G. Draetta, E. Karsenti, EMBO J. 13, 4302 (1994);
19. V. Sexl et al., Oncogene 18, 573 (1999).