53BP1, a mediator of the DNA damage checkpoint

Science

Volumn 298, Issue 5597, 2002, Pages 1435-1438

  Wang, Bin ^a   Matsuoka, Shuhei ^a   Carpenter, Phillip B ^a   Elledge, Stephen J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; IONIZING RADIATION; PROTEINS; RNA; SIGNALING; TUMORS;

PHOSPHORYLATION;

DNA;

BRCA1 PROTEIN; CHECKPOINT KINASE 2; PROTEIN 53BP1; PROTEIN DERIVATIVE; PROTEIN P53; RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

DNA; RNA;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN CELL; MAMMAL CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONTENT; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

BRCA1 PROTEIN; CARRIER PROTEINS; CELL CYCLE PROTEINS; DNA; DNA DAMAGE; G2 PHASE; HISTONES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOSIS; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING; RNA, SMALL INTERFERING; S PHASE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

MAMMALIA;

EID: 0037112212     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1076182     Document Type: Article

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24. We thank D. Cortez for helpful discussions; W. M. Bonner, T. D. Halazonetis, J. Qin, and J. Chen for providing antibodies; and T. Halazonetis for sharing unpublished checkpoint information and suggesting the use of 3GyIR. B.W. is a fellow of the U.S. Army Breast Cancer Postdoctoral Trainee Award, and S.J.E. is an Investigator with the Howard Hughes Medical Institute.