14-3-3σ controls mitotic translation to facilitate cytokinesis

Nature

Volumn 446, Issue 7133, 2007, Pages 329-332

  Wilker, Erik W ^a   Van Vugt, Marcel A T M ^a   Artim, Steven A ^a   Huang, Paul H ^b   Petersen, Christian P ^a   Reinhardt, H Christian ^a   Feng, Yun ^a   Sharp, Phillip A ^a   Sonenberg, Nahum ^c   White, Forest M ^b   Yaffe, Michael B ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CAPPED RNA; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 11; INITIATION FACTOR 4B; POLO LIKE KINASE 1; PROTEIN 14 3 3; PROTEIN 14 3 3 SIGMA; PROTEIN SUBUNIT; RAPAMYCIN; UNCLASSIFIED DRUG; EIF-4B; EXONUCLEASE; INITIATION FACTOR; SFN PROTEIN, HUMAN; TUMOR MARKER; TUMOR PROTEIN;

CANCER; DNA; ENZYME; GENE EXPRESSION; PROTEIN; TUMOR;

ARTICLE; BIOACCUMULATION; CYTOKINESIS; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; MITOSIS; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STOICHIOMETRY; TRANSLATION REGULATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY; PROTEIN SYNTHESIS; TUMOR CELL LINE;

EUKARYOTA;

CELL LINE, TUMOR; CYTOKINESIS; EUKARYOTIC INITIATION FACTORS; EXONUCLEASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MITOSIS; NEOPLASM PROTEINS; NEOPLASMS; PROTEIN BIOSYNTHESIS; RNA CAPS; TUMOR MARKERS, BIOLOGICAL;

EID: 33947236863     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05584     Document Type: Article

References (30)

1. Vercoutter-Edouart, A. S. et al. Proteomic analysis reveals that 14-3-3σ is down-regulated in human breast cancer cells. Cancer Res. 61, 76-80 (2001).
2. Ferguson, A. T. et al. High frequency of hypermethylation at the 14-3-3σ locus leads to gene silencing in breast cancer. Proc. Natl Acad. Sci. USA 97, 6049-6054 (2000).
3. Umbricht, C. B. et al. Hypermethylation of 14-3-3σ (stratifin) is an early event in breast cancer. Oncogene 20, 3348-3353 (2001).
4. Urano, T. et al. Efp targets 14-3-3σ for proteolysis and promotes breast tumour growth. Nature 417, 871-875 (2002).
5. Moreira, J. M., Gromov, P. & Celis, J. E. Expression of the tumor suppressor protein 14-3-3σ is down-regulated in invasive transitional cell carcinomas of the urinary bladder undergoing epithelial-to-mesenchymal transition. Mol. Cell. Proteomics 3, 410-419 (2004).
6. Iwata, N. et al. Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3σ gene in human hepatocellular carcinoma. Oncogene 19, 5298-5302 (2000).
7. Suzuki, H. et al. Inactivation of the 14-3-3σ gene is associated with 5′ CpG island hypermethylation in human cancers. Cancer Res. 60, 4353-4357 (2000).
8. Villaret, D. B. et al. Identification of genes overexpressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis. Laryngoscope 110, 374-381 (2000).
9. Gasco, M. et al. Coincident inactivation of 14-3-3′ and p16INK4a is an early event in vulval squamous neoplasia. Oncogene 21, 1876-1881 (2002).
10. Prescott, A. R. Synthesis of RNA and protein during mitosis in mammalian tissue culture cells. Exp. Cell Res. 26, 260-268 (1962).
11. Pyronnet, S., Dostie, J. & Sonenberg, N. Suppression of cap-dependent translation in mitosis. Genes Dev. 15, 2083-2093 (2001).
12. Pyronnet, S., Pradayrol, L. & Sonenberg, N. A cell cycle-dependent internal ribosome entry site. Mol. Cell 5, 607-616 (2000).
13. Qin, X. & Sarnow, P. Preferential translation of internal ribosome entry site-containing mRNAs during the mitotic cycle in mammalian cells. J. Biol. Chem. 279, 13721-13728 (2004).
14. Brasey, A. et al. The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycle. J. Virol. 77, 3939-3949 (2003).
15. Kullmann, M., Gopfert, U., Siewe, B. & Hengst, L. B. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR. Genes Dev. 16, 3087-3099 (2002).
16. Hershey, J. W. Expression of initiation factor genes in mammalian cells. Biochimie 76, 847-852 (1994).
17. Holcik, M. & Sonenberg, N. Translational control in stress and apoptosis. Nature Rev. Mol. Cell Biol. 6, 318-327 (2005).
18. Merrick, W. C. Cap-dependent and cap-independent translation in eukaryotic systems. Gene 332, 1-11 (2004).
19. Rogers, G. W. Jr, Richter, N. J. & Merrick, W. C. Biochemical and kinetic characterization of the RNA helicase activity of eukaryotic initiation factor 4A. J. Biol. Chem. 274, 12236-12244 (1999).
20. Neef, R. et al. Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J. Cell Biol. 162, 863-875 (2003).
21. Liu, X., Zhou, T., Kuriyama, R. & Erikson, R. L. Molecular interactions of Polo-like-kinase 1 with the mitotic kinesin-like protein CHO1/MKLP-1. J. Cell Sci. 117, 3233-3246 (2004).
22. Beretta, L., Gingras, A. C., Svitkin, Y. V., Hall, M. N. & Sonenberg, N. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. EMBO J. 15, 658-664 (1996).
23. p110/p58-null mutant mice at the blastocyst stage of embryonic cell development. Mol. Cell. Biol. 24, 3188-3197 (2004).
24. Petretti, C. et al. The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. EMBO Rep. 7, 418-424 (2006).
25. Cornelis, S. et al. Identification and characterization of a novel cell cycle-regulated internal ribosome entry site. Mol. Cell 5, 597-605 (2000).
26. Shi, Q. & King, R. W. Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. Nature 437, 1038-1042 (2005).
27. Fujiwara, T. et al. Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature 437, 1043-1047 (2005).
28. Brunet, A. et al. 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport. J. Cell Biol. 156, 817-828 (2002).
29. Wilker, E. W., Grant, R. A., Artim, S. C. & Yaffe, M. B. A structural basis for 14-3-3σ functional specificity. J. Biol. Chem. 280, 18891-18898 (2005).
30. Rubinson, D. A. et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nature Genet. 33, 401-406 (2003).