-
1
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
doi:10.1038/nature01368
-
Bakkenist, C.J., and M.B. Kastan. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature. 421:499-506. doi:10.1038/nature01368
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
2
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
doi:10.1074/jbc.C100466200
-
Burma, S., B.P. Chen, M. Murphy, A. Kurimasa, and D.J. Chen. 2001. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 276:42462-42467. doi:10.1074/jbc.C100466200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
3
-
-
0033020726
-
A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division
-
doi:10.1073/pnas.96.6.2828
-
Cai, S.Y., R.W. Babbitt, and V.T. Marchesi. 1999. A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division. Proc. Natl. Acad. Sci. USA. 96:2828-2833. doi:10.1073/pnas.96.6. 2828
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2828-2833
-
-
Cai, S.Y.1
Babbitt, R.W.2
Marchesi, V.T.3
-
4
-
-
73549109858
-
Safeguarding entry into mitosis: The antephase checkpoint
-
doi:10.1128/MCB.00687-09
-
Chin, C.F., and F.M. Yeong. 2010. Safeguarding entry into mitosis: the antephase checkpoint. Mol. Cell. Biol. 30:22-32. doi:10.1128/MCB.00687-09
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 22-32
-
-
Chin, C.F.1
Yeong, F.M.2
-
5
-
-
33947204449
-
Chromosome breakage after G2 checkpoint release
-
doi:10.1083/jcb.200612047
-
Deckbar, D., J. Birraux, A. Krempler, L. Tchouandong, A. Beucher, S. Walker, T. Stiff, P. Jeggo, and M. Löbrich. 2007. Chromosome breakage after G2 checkpoint release. J. Cell Biol. 176:749-755. doi:10.1083/jcb.200612047
-
(2007)
J. Cell Biol.
, vol.176
, pp. 749-755
-
-
Deckbar, D.1
Birraux, J.2
Krempler, A.3
Tchouandong, L.4
Beucher, A.5
Walker, S.6
Stiff, T.7
Jeggo, P.8
Löbrich, M.9
-
6
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
doi:10.1016/j.cell.2008.12.041
-
Doil, C., N. Mailand, S. Bekker-Jensen, P. Menard, D.H. Larsen, R. Pepperkok, J. Ellenberg, S. Panier, D. Durocher, J. Bartek, et al. 2009. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell. 136:435-446. doi:10.1016/j.cell.2008.12. 041
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
Ellenberg, J.7
Panier, S.8
Durocher, D.9
Bartek, J.10
-
7
-
-
15844394846
-
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
-
doi:10.1038/nature03442
-
Falck, J., J. Coates, and S.P. Jackson. 2005. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature. 434:605-611. doi:10.1038/nature03442
-
(2005)
Nature
, vol.434
, pp. 605-611
-
-
Falck, J.1
Coates, J.2
Jackson, S.P.3
-
8
-
-
70349308060
-
53BP1: Function and mechanisms of focal recruitment
-
doi:10.1042/BST0370897
-
FitzGerald, J.E., M. Grenon, and N.F. Lowndes. 2009. 53BP1: function and mechanisms of focal recruitment. Biochem. Soc. Trans. 37:897-904. doi:10.1042/BST0370897
-
(2009)
Biochem. Soc. Trans.
, vol.37
, pp. 897-904
-
-
FitzGerald, J.E.1
Grenon, M.2
Lowndes, N.F.3
-
9
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxiatelangiectasia mutated kinase ATM
-
doi:10.1158/0008-5472.CAN-04-2727
-
Hickson, I., Y. Zhao, C.J. Richardson, S.J. Green, N.M. Martin, A.I. Orr, P.M. Reaper, S.P. Jackson, N.J. Curtin, and G.C. Smith. 2004. Identification and characterization of a novel and specific inhibitor of the ataxiatelangiectasia mutated kinase ATM. Cancer Res. 64:9152-9159. doi:10.1158/0008-5472.CAN-04-2727
-
(2004)
Cancer Res.
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.5
Orr, A.I.6
Reaper, P.M.7
Jackson, S.P.8
Curtin, N.J.9
Smith, G.C.10
-
10
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
doi:10.1016/j.cell.2007.09.041
-
Huen, M.S., R. Grant, I. Manke, K. Minn, X. Yu, M.B. Yaffe, and J. Chen. 2007. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell. 131:901-914. doi:10.1016/j.cell.2007.09.041
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
Chen, J.7
-
11
-
-
25144461206
-
Phosphorylation of histone H2AX at M phase in human cells without DNA damage response
-
doi:10.1016/j.bbrc.2005.08.164
-
Ichijima, Y., R. Sakasai, N. Okita, K. Asahina, S. Mizutani, and H. Teraoka. 2005. Phosphorylation of histone H2AX at M phase in human cells without DNA damage response. Biochem. Biophys. Res. Commun. 336:807-812. doi:10.1016/j.bbrc.2005.08.164
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.336
, pp. 807-812
-
-
Ichijima, Y.1
Sakasai, R.2
Okita, N.3
Asahina, K.4
Mizutani, S.5
Teraoka, H.6
-
12
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
doi:10.1038/nature08467
-
Jackson, S.P., and J. Bartek. 2009. The DNA-damage response in human biology and disease. Nature. 461:1071-1078. doi:10.1038/nature08467
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
13
-
-
35548986309
-
Regulation of cell cycle progression and gene expression by H2A deubiquitination
-
doi:10.1038/nature06256
-
Joo, H.Y., L. Zhai, C. Yang, S. Nie, H. Erdjument-Bromage, P. Tempst, C. Chang, and H. Wang. 2007. Regulation of cell cycle progression and gene expression by H2A deubiquitination. Nature. 449:1068-1072. doi:10.1038/ nature06256
-
(2007)
Nature
, vol.449
, pp. 1068-1072
-
-
Joo, H.Y.1
Zhai, L.2
Yang, C.3
Nie, S.4
Erdjument-Bromage, H.5
Tempst, P.6
Chang, C.7
Wang, H.8
-
15
-
-
0036150875
-
Kinetochore localisation of the DNA damage response component 53BP1 during mitosis
-
Jullien, D., P. Vagnarelli, W.C. Earnshaw, and Y. Adachi. 2002. Kinetochore localisation of the DNA damage response component 53BP1 during mitosis. J. Cell Sci. 115:71-79. (Pubitemid 34105530)
-
(2002)
Journal of Cell Science
, vol.115
, Issue.1
, pp. 71-79
-
-
Jullien, D.1
Vagnarelli, P.2
Earnshaw, W.C.3
Adachi, Y.4
-
16
-
-
39249083653
-
Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosomes in G1-phase or in condensed metaphase cells
-
Kato, T.A., R. Okayasu, and J.S. Bedford. 2008. Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosomes in G1-phase or in condensed metaphase cells. Mutat. Res. 639:108-112.
-
(2008)
Mutat. Res.
, vol.639
, pp. 108-112
-
-
Kato, T.A.1
Okayasu, R.2
Bedford, J.S.3
-
17
-
-
64549100748
-
Signatures of DNA double strand breaks produced in irradiated G1 and G2 cells persist into mitosis
-
doi:10.1002/jcp.21726
-
Kato, T.A., R. Okayasu, and J.S. Bedford. 2009. Signatures of DNA double strand breaks produced in irradiated G1 and G2 cells persist into mitosis. J. Cell. Physiol. 219:760-765. doi:10.1002/jcp.21726
-
(2009)
J. Cell. Physiol.
, vol.219
, pp. 760-765
-
-
Kato, T.A.1
Okayasu, R.2
Bedford, J.S.3
-
18
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
doi:10.1126/science.1150034
-
Kolas, N.K., J.R. Chapman, S. Nakada, J. Ylanko, R. Chahwan, F.D. Sweeney, S. Panier, M. Mendez, J. Wildenhain, T.M. Thomson, et al. 2007. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science. 318:1637-1640. doi:10.1126/science.1150034
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
Panier, S.7
Mendez, M.8
Wildenhain, J.9
Thomson, T.M.10
-
19
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
doi:10.1038/227680a0
-
Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:680-685. doi:10.1038/227680a0
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
20
-
-
8844254050
-
Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries
-
doi:10.1016/j.bmcl.2004.09.060
-
Leahy, J.J., B.T. Golding, R.J. Griffin, I.R. Hardcastle, C. Richardson, L. Rigoreau, and G.C. Smith. 2004. Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries. Bioorg. Med. Chem. Lett. 14:6083-6087. doi:10.1016/j.bmcl.2004.09.060
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 6083-6087
-
-
Leahy, J.J.1
Golding, B.T.2
Griffin, R.J.3
Hardcastle, I.R.4
Richardson, C.5
Rigoreau, L.6
Smith, G.C.7
-
21
-
-
36248966246
-
RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins
-
DOI 10.1016/j.cell.2007.09.040, PII S0092867407012718
-
Mailand, N., S. Bekker-Jensen, H. Faustrup, F. Melander, J. Bartek, C. Lukas, and J. Lukas. 2007. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell. 131:887-900. doi:10.1016/j.cell.2007.09.040 (Pubitemid 350138084)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
Lukas, J.7
-
22
-
-
0008585058
-
Disappearance of a structural chromatin protein A24 in mitosis: Implications for molecular basis of chromatin condensation
-
doi:10.1073/pnas.76.12.6386
-
Matsui, S.I., B.K. Seon, and A.A. Sandberg. 1979. Disappearance of a structural chromatin protein A24 in mitosis: implications for molecular basis of chromatin condensation. Proc. Natl. Acad. Sci. USA. 76:6386-6390. doi:10.1073/pnas.76.12.6386
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 6386-6390
-
-
Matsui, S.I.1
Seon, B.K.2
Sandberg, A.A.3
-
23
-
-
26244439873
-
ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells
-
doi:10.1091/mbc.E05-01-0065
-
McManus, K.J., and M.J. Hendzel. 2005. ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. Mol. Biol. Cell. 16:5013-5025. doi:10.1091/mbc.E05-01-0065
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 5013-5025
-
-
McManus, K.J.1
Hendzel, M.J.2
-
24
-
-
0037195281
-
DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint
-
DOI 10.1016/S0960-9822(02)01226-5, PII S0960982202012265
-
Mikhailov, A., R.W. Cole, and C.L. Rieder. 2002. DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint. Curr. Biol. 12:1797-1806. doi:10.1016/S0960- 9822(02)01226-5 (Pubitemid 35273899)
-
(2002)
Current Biology
, vol.12
, Issue.21
, pp. 1797-1806
-
-
Mikhailov, A.1
Cole, R.W.2
Rieder, C.L.3
-
25
-
-
33745198661
-
Techniques for gamma-H2AX detection
-
doi:10.1016/S0076-6879(05)09014-2
-
Nakamura, A., O.A. Sedelnikova, C. Redon, D.R. Pilch, N.I. Sinogeeva, R. Shroff, M. Lichten, and W.M. Bonner. 2006. Techniques for gamma-H2AX detection. Methods Enzymol. 409:236-250. doi:10.1016/S0076-6879(05)09014-2
-
(2006)
Methods Enzymol.
, vol.409
, pp. 236-250
-
-
Nakamura, A.1
Sedelnikova, O.A.2
Redon, C.3
Pilch, D.R.4
Sinogeeva, N.I.5
Shroff, R.6
Lichten, M.7
Bonner, W.M.8
-
26
-
-
70350222196
-
DNA damage foci in mitosis are devoid of 53BP1
-
Nelson, G., M. Buhmann, and T. von Zglinicki. 2009. DNA damage foci in mitosis are devoid of 53BP1. Cell Cycle. 8:3379-3383.
-
(2009)
Cell Cycle
, vol.8
, pp. 3379-3383
-
-
Nelson, G.1
Buhmann, M.2
Von Zglinicki, T.3
-
27
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
doi:10.1016/S0960-9822(00)00610-2
-
Paull, T.T., E.P. Rogakou, V. Yamazaki, C.U. Kirchgessner, M. Gellert, and W.M. Bonner. 2000. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10:886-895. doi:10.1016/S0960-9822(00)00610-2
-
(2000)
Curr. Biol.
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
28
-
-
67649404816
-
RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
-
doi:10.1186/1471-2199-10-55
-
Pinato, S., C. Scandiuzzi, N. Arnaudo, E. Citterio, G. Gaudino, and L. Penengo. 2009. RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX. BMC Mol. Biol. 10:55-69. doi:10.1186/1471-2199-10-55
-
(2009)
BMC Mol. Biol.
, vol.10
, pp. 55-69
-
-
Pinato, S.1
Scandiuzzi, C.2
Arnaudo, N.3
Citterio, E.4
Gaudino, G.5
Penengo, L.6
-
29
-
-
0035144407
-
Re-staging mitosis: A contemporary view of mitotic progression
-
doi:10.1038/35050676
-
Pines, J., and C.L. Rieder. 2001. Re-staging mitosis: a contemporary view of mitotic progression. Nat. Cell Biol. 3:E3-E6. doi:10.1038/35050676
-
(2001)
Nat. Cell Biol.
, vol.3
-
-
Pines, J.1
Rieder, C.L.2
-
30
-
-
39849092543
-
Regulation of mitotic exit by the RNF8 ubiquitin ligase
-
DOI 10.1038/sj.onc.1210782, PII 1210782
-
Plans, V., M. Guerra-Rebollo, and T.M. Thomson. 2008. Regulation of mitotic exit by the RNF8 ubiquitin ligase. Oncogene. 27:1355-1365. doi:10.1038/sj.onc.1210782 (Pubitemid 351317468)
-
(2008)
Oncogene
, vol.27
, Issue.10
, pp. 1355-1365
-
-
Plans, V.1
Guerra-Rebollo, M.2
Thomson, T.M.3
-
31
-
-
34247131430
-
Mitotic phosphorylation: Breaking the balance of power by a tactical retreat
-
doi:10.1042/BJ20070290
-
Poon, R.Y. 2007. Mitotic phosphorylation: breaking the balance of power by a tactical retreat. Biochem. J. 403:e5-e7. doi:10.1042/BJ20070290
-
(2007)
Biochem. J.
, vol.403
-
-
Poon, R.Y.1
-
32
-
-
0032563638
-
Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase
-
doi:10.1083/jcb.142.4.1013
-
Rieder, C.L., and R.W. Cole. 1998. Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase. J. Cell Biol. 142:1013-1022. doi:10.1083/jcb.142.4.1013
-
(1998)
J. Cell Biol.
, vol.142
, pp. 1013-1022
-
-
Rieder, C.L.1
Cole, R.W.2
-
33
-
-
0032146974
-
The vertebrate cell kinetochore and its roles during mitosis
-
doi:10.1016/S0962-8924(98)01299-9
-
Rieder, C.L., and E.D. Salmon. 1998. The vertebrate cell kinetochore and its roles during mitosis. Trends Cell Biol. 8:310-318. doi:10.1016/S0962- 8924(98)01299-9
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 310-318
-
-
Rieder, C.L.1
Salmon, E.D.2
-
34
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
doi:10.1074/jbc.273.10.5858
-
Rogakou, E.P., D.R. Pilch, A.H. Orr, V.S. Ivanova, and W.M. Bonner. 1998. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273:5858-5868. doi:10.1074/jbc.273.10.5858
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
35
-
-
0034739853
-
p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
-
doi:10.1083/jcb.151.7.1381
-
Schultz, L.B., N.H. Chehab, A. Malikzay, and T.D. Halazonetis. 2000. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol. 151:1381-1390. doi:10.1083/jcb.151.7. 1381
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1381-1390
-
-
Schultz, L.B.1
Chehab, N.H.2
Malikzay, A.3
Halazonetis, T.D.4
-
36
-
-
66849138419
-
Solving the RIDDLE of 53BP1 recruitment to sites of damage
-
Stewart, G.S. 2009. Solving the RIDDLE of 53BP1 recruitment to sites of damage. Cell Cycle. 8:1532-1538.
-
(2009)
Cell Cycle
, vol.8
, pp. 1532-1538
-
-
Stewart, G.S.1
-
37
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
doi:10.1016/j.cell.2008.12.042
-
Stewart, G.S., S. Panier, K. Townsend, A.K. Al-Hakim, N.K. Kolas, E.S. Miller, S. Nakada, J. Ylanko, S. Olivarius, M. Mendez, et al. 2009. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell. 136:420-434. doi:10.1016/j.cell.2008.12.042
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
Nakada, S.7
Ylanko, J.8
Olivarius, S.9
Mendez, M.10
-
38
-
-
1942538492
-
ATM and DNA-PK Function Redundantly to Phosphorylate H2AX after Exposure to Ionizing Radiation
-
DOI 10.1158/0008-5472.CAN-03-3207
-
Stiff, T., M. O'Driscoll, N. Rief, K. Iwabuchi, M. Löbrich, and P.A. Jeggo. 2004. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 64:2390-2396. doi:10.1158/0008-5472. CAN-03-3207 (Pubitemid 38523891)
-
(2004)
Cancer Research
, vol.64
, Issue.7
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
39
-
-
18744398382
-
The radiation hypersensitivity of cells at mitosis
-
doi:10.1080/09553000210166570
-
Stobbe, C.C., S.J. Park, and J.D. Chapman. 2002. The radiation hypersensitivity of cells at mitosis. Int. J. Radiat. Biol. 78:1149-1157. doi:10.1080/09553000210166570
-
(2002)
Int. J. Radiat. Biol.
, vol.78
, pp. 1149-1157
-
-
Stobbe, C.C.1
Park, S.J.2
Chapman, J.D.3
-
40
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
DOI 10.1016/j.cell.2005.09.038, PII S0092867405011657
-
Stucki, M., J.A. Clapperton, D. Mohammad, M.B. Yaffe, S.J. Smerdon, and S.P. Jackson. 2005. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell. 123:1213-1226. doi:10.1016/j.cell.2005.09.038 (Pubitemid 41821780)
-
(2005)
Cell
, vol.123
, Issue.7
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
41
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
doi:10.1016/j.tcb.2009.03.001
-
van Attikum, H., and S.M. Gasser. 2009. Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol. 19:207-217. doi:10.1016/j.tcb.2009.03.001
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 207-217
-
-
Van Attikum, H.1
Gasser, S.M.2
-
42
-
-
75749130721
-
A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint
-
doi:10.1371/journal.pbio.1000287
-
van Vugt, M.A., A.K. Gardino, R. Linding, G.J. Ostheimer, H.C. Reinhardt, S.E. Ong, C.S. Tan, H. Miao, S.M. Keezer, J. Li, et al. 2010. A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint. PLoS Biol. 8:e1000287. doi:10.1371/journal.pbio.1000287
-
(2010)
PLoS Biol.
, vol.8
-
-
Van Vugt, M.A.1
Gardino, A.K.2
Linding, R.3
Ostheimer, G.J.4
Reinhardt, H.C.5
Ong, S.E.6
Tan, C.S.7
Miao, H.8
Keezer, S.M.9
Li, J.10
-
43
-
-
11144305946
-
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors
-
DOI 10.1002/jcp.20141
-
Wang, H., M. Wang, H. Wang, W. Böcker, and G. Iliakis. 2005. Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors. J. Cell. Physiol. 202:492-502. doi:10.1002/jcp.20141 (Pubitemid 40041320)
-
(2005)
Journal of Cellular Physiology
, vol.202
, Issue.2
, pp. 492-502
-
-
Wang, H.1
Wang, M.2
Wang, H.3
Bocker, W.4
Iliakis, G.5
-
44
-
-
34948899943
-
Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template
-
doi:10.1139/O07-069
-
Williams, R.S., J.S. Williams, and J.A. Tainer. 2007. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template. Biochem. Cell Biol. 85:509-520. doi:10.1139/O07-069
-
(2007)
Biochem. Cell Biol.
, vol.85
, pp. 509-520
-
-
Williams, R.S.1
Williams, J.S.2
Tainer, J.A.3
-
45
-
-
0037424296
-
NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways
-
doi:10.1074/jbc.M211392200
-
Xu, X., and D.F. Stern. 2003. NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. J. Biol. Chem. 278:8795-8803. doi:10.1074/jbc.M211392200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8795-8803
-
-
Xu, X.1
Stern, D.F.2
-
46
-
-
52949139387
-
AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
-
doi:10.1158/1535-7163.MCT-08-0492
-
Zabludoff, S.D., C. Deng, M.R. Grondine, A.M. Sheehy, S. Ashwell, B.L. Caleb, S. Green, H.R. Haye, C.L. Horn, J.W. Janetka, et al. 2008. AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies. Mol. Cancer Ther. 7:2955-2966. doi:10.1158/1535-7163. MCT-08-0492
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2955-2966
-
-
Zabludoff, S.D.1
Deng, C.2
Grondine, M.R.3
Sheehy, A.M.4
Ashwell, S.5
Caleb, B.L.6
Green, S.7
Haye, H.R.8
Horn, C.L.9
Janetka, J.W.10
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