-
1
-
-
36949005417
-
DNA damage signalling guards against activated oncogenes and tumour progression
-
Bartek, J., J. Bartkova, and J. Lukas. 2007. DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene. 26:7773-7779. http://dx.doi.org/10.1038/sj.onc.1210881
-
(2007)
Oncogene
, vol.26
, pp. 7773-7779
-
-
Bartek, J.1
Bartkova, J.2
Lukas, J.3
-
2
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova, J., Z. Horejsí, K. Koed, A. Krämer, F. Tort, K. Zieger, P. Guldberg, M. Sehested, J.M. Nesland, C. Lukas, et al. 2005. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature. 434:864-870. http://dx.doi.org/10.1038/nature03482
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsí, Z.2
Koed, K.3
Krämer, A.4
Tort, F.5
Zieger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.M.9
Lukas, C.10
-
3
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova, J., N. Rezaei, M. Liontos, P. Karakaidos, D. Kletsas, N. Issaeva, L.V. Vassiliou, E. Kolettas, K. Niforou, V.C. Zoumpourlis, et al. 2006. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature. 444:633-637. http://dx.doi.org/10.1038/nature05268
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
Vassiliou, L.V.7
Kolettas, E.8
Niforou, K.9
Zoumpourlis, V.C.10
-
4
-
-
77949410508
-
Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
-
Beck, H., V. Nähse, M.S. Larsen, P. Groth, T. Clancy, M. Lees, M. Jørgensen, T. Helleday, R.G. Syljuåsen, and C.S. Sørensen. 2010. Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase. J. Cell Biol. 188:629-638. http://dx.doi.org/10.1083/jcb.200905059
-
(2010)
J. Cell Biol
, vol.188
, pp. 629-638
-
-
Beck, H.1
Nähse, V.2
Larsen, M.S.3
Groth, P.4
Clancy, T.5
Lees, M.6
Jørgensen, M.7
Helleday, T.8
Syljuåsen, R.G.9
Sørensen, C.S.10
-
5
-
-
79960802984
-
The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores
-
Bermejo, R., T. Capra, R. Jossen, A. Colosio, C. Frattini, W. Carotenuto, A. Cocito, Y. Doksani, H. Klein, B. Gómez-González, et al. 2011. The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell. 146:233-246. http://dx.doi.org/10.1016/j.cell.2011.06.033
-
(2011)
Cell
, vol.146
, pp. 233-246
-
-
Bermejo, R.1
Capra, T.2
Jossen, R.3
Colosio, A.4
Frattini, C.5
Carotenuto, W.6
Cocito, A.7
Doksani, Y.8
Klein, H.9
Gómez-González, B.10
-
6
-
-
84859042868
-
Preventing replication stress to maintain genome stability: resolving conflicts between replication and transcription
-
Bermejo, R., M.S. Lai, and M. Foiani. 2012. Preventing replication stress to maintain genome stability: resolving conflicts between replication and transcription. Mol. Cell. 45:710-718. http://dx.doi.org/10.1016/j.molcel.2012.03.001
-
(2012)
Mol. Cell
, vol.45
, pp. 710-718
-
-
Bermejo, R.1
Lai, M.S.2
Foiani, M.3
-
7
-
-
79955525482
-
Nucleotide deficiency promotes genomic instability in early stages of cancer development
-
Bester, A.C., M. Roniger, Y.S. Oren, M.M. Im, D. Sarni, M. Chaoat, A. Bensimon, G. Zamir, D.S. Shewach, and B. Kerem. 2011. Nucleotide deficiency promotes genomic instability in early stages of cancer development. Cell. 145:435-446. http://dx.doi.org/10.1016/j.cell.2011.03.044
-
(2011)
Cell
, vol.145
, pp. 435-446
-
-
Bester, A.C.1
Roniger, M.2
Oren, Y.S.3
Im, M.M.4
Sarni, D.5
Chaoat, M.6
Bensimon, A.7
Zamir, G.8
Shewach, D.S.9
Kerem, B.10
-
8
-
-
84856424908
-
DNA breaks and chromosome pulverization from errors in mitosis
-
Crasta, K., N.J. Ganem, R. Dagher, A.B. Lantermann, E.V. Ivanova, Y. Pan, L. Nezi, A. Protopopov, D. Chowdhury, and D. Pellman. 2012. DNA breaks and chromosome pulverization from errors in mitosis. Nature. 482:53-58. http://dx.doi.org/10.1038/nature10802
-
(2012)
Nature
, vol.482
, pp. 53-58
-
-
Crasta, K.1
Ganem, N.J.2
Dagher, R.3
Lantermann, A.B.4
Ivanova, E.V.5
Pan, Y.6
Nezi, L.7
Protopopov, A.8
Chowdhury, D.9
Pellman, D.10
-
9
-
-
0020754610
-
Monoclonal antibodies to mitotic cells
-
USA
-
Davis, F.M., T.Y. Tsao, S.K. Fowler, and P.N. Rao. 1983. Monoclonal antibodies to mitotic cells. Proc. Natl. Acad. Sci. USA. 80:2926-2930. http://dx.doi.org/10.1073/pnas.80.10.2926
-
(1983)
Proc. Natl. Acad. Sci.
, vol.83
, pp. 2926-2930
-
-
Davis, F.M.1
Tsao, T.Y.2
Fowler, S.K.3
Rao, P.N.4
-
10
-
-
77950932096
-
Persistent telomere damage induces bypass of mitosis and tetraploidy
-
Davoli, T., E.L. Denchi, and T. de Lange. 2010. Persistent telomere damage induces bypass of mitosis and tetraploidy. Cell. 141:81-93. http://dx.doi.org/10.1016/j.cell.2010.01.031
-
(2010)
Cell
, vol.141
, pp. 81-93
-
-
Davoli, T.1
Denchi, E.L.2
de Lange, T.3
-
11
-
-
77951026398
-
A minority of foci or pan-nuclear apoptotic staining of gammaH2AX in the S phase after UV damage contain DNA double-strand breaks
-
USA
-
de Feraudy, S., I. Revet, V. Bezrookove, L. Feeney, and J.E. Cleaver. 2010. A minority of foci or pan-nuclear apoptotic staining of gammaH2AX in the S phase after UV damage contain DNA double-strand breaks. Proc. Natl. Acad. Sci. USA. 107:6870-6875. http://dx.doi.org/10.1073/pnas.1002175107
-
(2010)
Proc. Natl. Acad. Sci
, vol.107
, pp. 6870-6875
-
-
de Feraudy, S.1
Revet, I.2
Bezrookove, V.3
Feeney, L.4
Cleaver, J.E.5
-
12
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco, R., M. Fumagalli, A. Cicalese, S. Piccinin, P. Gasparini, C. Luise, C. Schurra, M. Garre', P.G. Nuciforo, A. Bensimon, et al. 2006. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature. 444:638-642. http://dx.doi.org/10.1038/nature05327
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre', M.8
Nuciforo, P.G.9
Bensimon, A.10
-
13
-
-
80052632895
-
Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease
-
Domínguez-Kelly, R., Y. Martín, S. Koundrioukoff, M.E. Tanenbaum, V.A. Smits, R.H. Medema, M. Debatisse, and R. Freire. 2011. Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease. J. Cell Biol. 194:567-579. http://dx.doi.org/10.1083/jcb.201101047
-
(2011)
J. Cell Biol
, vol.194
, pp. 567-579
-
-
Domínguez-Kelly, R.1
Martín, Y.2
Koundrioukoff, S.3
Tanenbaum, M.E.4
Smits, V.A.5
Medema, R.H.6
Debatisse, M.7
Freire, R.8
-
14
-
-
34547232986
-
Non-transcriptional control of DNA replication by c-Myc
-
Dominguez-Sola, D., C.Y. Ying, C. Grandori, L. Ruggiero, B. Chen, M. Li, D.A. Galloway, W. Gu, J. Gautier, and R. Dalla-Favera. 2007. Non-transcriptional control of DNA replication by c-Myc. Nature. 448:445-451. http://dx.doi.org/10.1038/nature05953
-
(2007)
Nature
, vol.448
, pp. 445-451
-
-
Dominguez-Sola, D.1
Ying, C.Y.2
Grandori, C.3
Ruggiero, L.4
Chen, B.5
Li, M.6
Galloway, D.A.7
Gu, W.8
Gautier, J.9
Dalla-Favera, R.10
-
15
-
-
80051758435
-
Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation
-
Forment, J.V., M. Blasius, I. Guerini, and S.P. Jackson. 2011. Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation. PLoS ONE. 6:e23517. http://dx.doi.org/10.1371/journal.pone.0023517
-
(2011)
PLoS ONE
, vol.6
-
-
Forment, J.V.1
Blasius, M.2
Guerini, I.3
Jackson, S.P.4
-
16
-
-
77954997032
-
DNA damage signaling in response to double-strand breaks during mitosis
-
Giunta, S., R. Belotserkovskaya, and S.P. Jackson. 2010. DNA damage signaling in response to double-strand breaks during mitosis. J. Cell Biol. 190:197-207. http://dx.doi.org/10.1083/jcb.200911156
-
(2010)
J. Cell Biol
, vol.190
, pp. 197-207
-
-
Giunta, S.1
Belotserkovskaya, R.2
Jackson, S.P.3
-
17
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis, V.G., L.V. Vassiliou, P. Karakaidos, P. Zacharatos, A. Kotsinas, T. Liloglou, M. Venere, R.A. Ditullio Jr., N.G. Kastrinakis, B. Levy, et al. 2005. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature. 434:907-913. http://dx.doi.org/10.1038/nature03485
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
Venere, M.7
Ditullio, Jr.R.A.8
Kastrinakis, N.G.9
Levy, B.10
-
18
-
-
33750206776
-
The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks
-
Hanada, K., M. Budzowska, M. Modesti, A. Maas, C. Wyman, J. Essers, and R. Kanaar. 2006. The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J. 25:4921-4932. http://dx.doi.org/10.1038/sj.emboj.7601344
-
(2006)
EMBO J
, vol.25
, pp. 4921-4932
-
-
Hanada, K.1
Budzowska, M.2
Modesti, M.3
Maas, A.4
Wyman, C.5
Essers, J.6
Kanaar, R.7
-
19
-
-
35848930133
-
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
-
Hanada, K., M. Budzowska, S.L. Davies, E. van Drunen, H. Onizawa, H.B. Beverloo, A. Maas, J. Essers, I.D. Hickson, and R. Kanaar. 2007. The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nat. Struct. Mol. Biol. 14:1096-1104. http://dx.doi.org/10.1038/nsmb1313
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 1096-1104
-
-
Hanada, K.1
Budzowska, M.2
Davies, S.L.3
van Drunen, E.4
Onizawa, H.5
Beverloo, H.B.6
Maas, A.7
Essers, J.8
Hickson, I.D.9
Kanaar, R.10
-
20
-
-
0017298802
-
A model for replication repair in mammalian cells
-
Higgins, N.P., K. Kato, and B. Strauss. 1976. A model for replication repair in mammalian cells. J. Mol. Biol. 101:417-425. http://dx.doi.org/10.1016/0022-2836(76)90156-X
-
(1976)
J. Mol. Biol
, vol.101
, pp. 417-425
-
-
Higgins, N.P.1
Kato, K.2
Strauss, B.3
-
21
-
-
77952526077
-
DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development
-
Ichijima, Y., K. Yoshioka, Y. Yoshioka, K. Shinohe, H. Fujimori, J. Unno, M. Takagi, H. Goto, M. Inagaki, S. Mizutani, and H. Teraoka. 2010. DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development. PLoS ONE. 5:e8821. http://dx.doi.org/10.1371/journal.pone.0008821
-
(2010)
PLoS ONE
, vol.5
-
-
Ichijima, Y.1
Yoshioka, K.2
Yoshioka, Y.3
Shinohe, K.4
Fujimori, H.5
Unno, J.6
Takagi, M.7
Goto, H.8
Inagaki, M.9
Mizutani, S.10
Teraoka, H.11
-
22
-
-
0032559794
-
Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells
-
Jackson, D.A., and A. Pombo. 1998. Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells. J. Cell Biol. 140:1285-1295. http://dx.doi.org/10.1083/jcb.140.6.1285
-
(1998)
J. Cell Biol
, vol.140
, pp. 1285-1295
-
-
Jackson, D.A.1
Pombo, A.2
-
23
-
-
84881480253
-
Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress
-
Jones, R.M., O. Mortusewicz, I. Afzal, M. Lorvellec, P. Garcia, T. Helleday, and E. Petermann. 2012. Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress. Oncogene. http://dx.doi.org/10.1038/onc.2012.387
-
(2012)
Oncogene
-
-
Jones, R.M.1
Mortusewicz, O.2
Afzal, I.3
Lorvellec, M.4
Garcia, P.5
Helleday, T.6
Petermann, E.7
-
24
-
-
79952281751
-
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
-
Lukas, C., V. Savic, S. Bekker-Jensen, C. Doil, B. Neumann, R.S. Pedersen, M. Grøfte, K.L. Chan, I.D. Hickson, J. Bartek, and J. Lukas. 2011. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nat. Cell Biol. 13:243-253. http://dx.doi.org/10.1038/ncb2201
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 243-253
-
-
Lukas, C.1
Savic, V.2
Bekker-Jensen, S.3
Doil, C.4
Neumann, B.5
Pedersen, R.S.6
Grøfte, M.7
Chan, K.L.8
Hickson, I.D.9
Bartek, J.10
Lukas, J.11
-
25
-
-
0034717309
-
Rapid destruction of human Cdc25A in response to DNA damage
-
Mailand, N., J. Falck, C. Lukas, R.G. Syljuâsen, M. Welcker, J. Bartek, and J. Lukas. 2000. Rapid destruction of human Cdc25A in response to DNA damage. Science. 288:1425-1429. http://dx.doi.org/10.1126/science.288.5470.1425
-
(2000)
Science
, vol.288
, pp. 1425-1429
-
-
Mailand, N.1
Falck, J.2
Lukas, C.3
Syljuâsen, R.G.4
Welcker, M.5
Bartek, J.6
Lukas, J.7
-
26
-
-
80053544629
-
Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis
-
Matos, J., M.G. Blanco, S. Maslen, J.M. Skehel, and S.C. West. 2011. Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell. 147:158-172. http://dx.doi.org/10.1016/j.cell.2011.08.032
-
(2011)
Cell
, vol.147
, pp. 158-172
-
-
Matos, J.1
Blanco, M.G.2
Maslen, S.3
Skehel, J.M.4
West, S.C.5
-
27
-
-
26244439873
-
ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells
-
McManus, K.J., and M.J. Hendzel. 2005. ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. Mol. Biol. Cell. 16:5013-5025. http://dx.doi.org/10.1091/mbc.E05-01-0065
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 5013-5025
-
-
McManus, K.J.1
Hendzel, M.J.2
-
28
-
-
0034232093
-
Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis
-
Molinari, M., C. Mercurio, J. Dominguez, F. Goubin, and G.F. Draetta. 2000. Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis. EMBO Rep. 1:71-79. http://dx.doi.org/10.1093/embo-reports/kvd018
-
(2000)
EMBO Rep
, vol.1
, pp. 71-79
-
-
Molinari, M.1
Mercurio, C.2
Dominguez, J.3
Goubin, F.4
Draetta, G.F.5
-
29
-
-
84873412967
-
The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation
-
Murfuni, I., S. Nicolai, S. Baldari, M. Crescenzi, M. Bignami, A. Franchitto, and P. Pichierri. 2013. The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation. Oncogene. 32:610-620 http://dx.doi.org/10.1038/onc.2012.80.
-
(2013)
Oncogene
, vol.32
, pp. 610-620
-
-
Murfuni, I.1
Nicolai, S.2
Baldari, S.3
Crescenzi, M.4
Bignami, M.5
Franchitto, A.6
Pichierri, P.7
-
30
-
-
68149161607
-
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
-
Murga, M., S. Bunting, M.F. Montaña, R. Soria, F. Mulero, M. Cañamero, Y. Lee, P.J. McKinnon, A. Nussenzweig, and O. Fernandez-Capetillo. 2009. A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging. Nat. Genet. 41:891-898. http://dx.doi.org/10.1038/ng.420
-
(2009)
Nat. Genet
, vol.41
, pp. 891-898
-
-
Murga, M.1
Bunting, S.2
Montaña, M.F.3
Soria, R.4
Mulero, F.5
Cañamero, M.6
Lee, Y.7
McKinnon, P.J.8
Nussenzweig, A.9
Fernandez-Capetillo, O.10
-
31
-
-
84875213156
-
Visualization and interpretation of eukaryotic DNA replication intermediates by electron microscopy in vivo
-
In press
-
Neelsen, K.J., A. Ray Chaudhuri, C. Follonier, R. Herrador, and M. Lopes. 2013. Visualization and interpretation of eukaryotic DNA replication intermediates by electron microscopy in vivo. Methods Mol. Biol. In press.
-
(2013)
Methods Mol. Biol
-
-
Neelsen, K.J.1
Ray Chaudhuri, A.2
Follonier, C.3
Herrador, R.4
Lopes, M.5
-
32
-
-
0035951787
-
Positive torsional strain causes the formation of a four-way junction at replication forks
-
Postow, L., C. Ullsperger, R.W. Keller, C. Bustamante, A.V. Vologodskii, and N.R. Cozzarelli. 2001. Positive torsional strain causes the formation of a four-way junction at replication forks. J. Biol. Chem. 276:2790-2796. http://dx.doi.org/10.1074/jbc.M006736200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 2790-2796
-
-
Postow, L.1
Ullsperger, C.2
Keller, R.W.3
Bustamante, C.4
Vologodskii, A.V.5
Cozzarelli, N.R.6
-
33
-
-
84861322877
-
Topoisomerase I poisoning results in PARP-mediated replication fork reversal
-
Ray Chaudhuri, A., Y. Hashimoto, R. Herrador, K.J. Neelsen, D. Fachinetti, R. Bermejo, A. Cocito, V. Costanzo, and M. Lopes. 2012. Topoisomerase I poisoning results in PARP-mediated replication fork reversal. Nat. Struct. Mol. Biol. 19:417-423. http://dx.doi.org/10.1038/nsmb.2258
-
(2012)
Nat. Struct. Mol. Biol
, vol.19
, pp. 417-423
-
-
Ray Chaudhuri, A.1
Hashimoto, Y.2
Herrador, R.3
Neelsen, K.J.4
Fachinetti, D.5
Bermejo, R.6
Cocito, A.7
Costanzo, V.8
Lopes, M.9
-
34
-
-
79955522790
-
Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes
-
Schwartz, E.K., and W.D. Heyer. 2011. Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes. Chromosoma. 120:109-127. http://dx.doi.org/10.1007/s00412-010-0304-7
-
(2011)
Chromosoma
, vol.120
, pp. 109-127
-
-
Schwartz, E.K.1
Heyer, W.D.2
-
35
-
-
0037178740
-
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
-
Sogo, J.M., M. Lopes, and M. Foiani. 2002. Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science. 297:599-602. http://dx.doi.org/10.1126/science.1074023
-
(2002)
Science
, vol.297
, pp. 599-602
-
-
Sogo, J.M.1
Lopes, M.2
Foiani, M.3
-
36
-
-
41649092091
-
Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures
-
USA
-
Taylor, E.R., and C.H. McGowan. 2008. Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures. Proc. Natl. Acad. Sci. USA. 105:3757-3762. http://dx.doi.org/10.1073/pnas.0710291105
-
(2008)
Proc. Natl. Acad. Sci
, vol.105
, pp. 3757-3762
-
-
Taylor, E.R.1
McGowan, C.H.2
-
37
-
-
79958865837
-
A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations
-
Toledo, L.I., M. Murga, R. Zur, R. Soria, A. Rodriguez, S. Martinez, J. Oyarzabal, J. Pastor, J.R. Bischoff, and O. Fernandez-Capetillo. 2011. A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. Nat. Struct. Mol. Biol. 18:721-727. http://dx.doi.org/10.1038/nsmb.2076
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 721-727
-
-
Toledo, L.I.1
Murga, M.2
Zur, R.3
Soria, R.4
Rodriguez, A.5
Martinez, S.6
Oyarzabal, J.7
Pastor, J.8
Bischoff, J.R.9
Fernandez-Capetillo, O.10
-
38
-
-
80052607184
-
Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells
-
USA
-
Toller, I.M., K.J. Neelsen, M. Steger, M.L. Hartung, M.O. Hottiger, M. Stucki, B. Kalali, M. Gerhard, A.A. Sartori, M. Lopes, and A. Müller. 2011. Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells. Proc. Natl. Acad. Sci. USA. 108:14944-14949. http://dx.doi.org/10.1073/pnas.1100959108
-
(2011)
Proc. Natl. Acad. Sci
, vol.108
, pp. 14944-14949
-
-
Toller, I.M.1
Neelsen, K.J.2
Steger, M.3
Hartung, M.L.4
Hottiger, M.O.5
Stucki, M.6
Kalali, B.7
Gerhard, M.8
Sartori, A.A.9
Lopes, M.10
Müller, A.11
-
39
-
-
33746094659
-
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1
-
USA
-
Vassilev, L.T., C. Tovar, S. Chen, D. Knezevic, X. Zhao, H. Sun, D.C. Heimbrook, and L. Chen. 2006. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc. Natl. Acad. Sci. USA. 103:10660-10665. http://dx.doi.org/10.1073/pnas.0600447103
-
(2006)
Proc. Natl. Acad. Sci
, vol.103
, pp. 10660-10665
-
-
Vassilev, L.T.1
Tovar, C.2
Chen, S.3
Knezevic, D.4
Zhao, X.5
Sun, H.6
Heimbrook, D.C.7
Chen, L.8
-
40
-
-
3543041247
-
53 status and activates a G2/M checkpoint
-
Zhu, W., Y. Chen, and A. Dutta. 2004. Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint. Mol. Cell. Biol. 24:7140-7150. http://dx.doi.org/10.1128/MCB.24.16.7140-7150.2004
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 7140-7150
-
-
Zhu, W.1
Chen, Y.2
Dutta, A.3
|