-
1
-
-
33845604556
-
DNA double-strand break repair: All's well that ends well
-
Wyman, C. & Kanaar, R. DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet. 40, 363-383 (2006).
-
(2006)
Annu. Rev. Genet
, vol.40
, pp. 363-383
-
-
Wyman, C.1
Kanaar, R.2
-
2
-
-
0042839614
-
Mechanism and regulation of human non-homologous DNA end-joining
-
Lieber, M. R., Ma, Y., Pannicke, U. & Schwarz, K. Mechanism and regulation of human non-homologous DNA end-joining. Nature Rev. Mol. Cell Biol. 4, 712-720 (2003).
-
(2003)
Nature Rev. Mol. Cell Biol
, vol.4
, pp. 712-720
-
-
Lieber, M.R.1
Ma, Y.2
Pannicke, U.3
Schwarz, K.4
-
3
-
-
0038700698
-
Molecular views of recombination proteins and their control
-
West, S. C. Molecular views of recombination proteins and their control. Nature Rev. Mol. Cell Biol. 4, 435-445 (2003).
-
(2003)
Nature Rev. Mol. Cell Biol
, vol.4
, pp. 435-445
-
-
West, S.C.1
-
4
-
-
33749037701
-
Mechanism of homologous recombination: Mediators and helicases take on regulatory functions
-
Sung, P. & Klein, H. Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nature Rev. Mol. Cell Biol. 7, 739-750 (2006).
-
(2006)
Nature Rev. Mol. Cell Biol
, vol.7
, pp. 739-750
-
-
Sung, P.1
Klein, H.2
-
5
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou, L. & Elledge, S. J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300, 1542-1548 (2003).
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
6
-
-
7244220162
-
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
-
Ira, G. et al. DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature 431, 1011-1017 (2004).
-
(2004)
Nature
, vol.431
, pp. 1011-1017
-
-
Ira, G.1
-
7
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
Jazayeri, A. et al. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nature Cell Biol. 8, 37-45 (2006).
-
(2006)
Nature Cell Biol
, vol.8
, pp. 37-45
-
-
Jazayeri, A.1
-
8
-
-
11244269445
-
The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
-
Aylon, Y., Liefshitz, B. & Kupiec, M. The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J. 23, 4868-4875 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 4868-4875
-
-
Aylon, Y.1
Liefshitz, B.2
Kupiec, M.3
-
9
-
-
4544333242
-
The Mre11 complex and ATM: A two-way functional interaction in recognising and signaling DNA double strand breaks
-
Lavin, M. F. The Mre11 complex and ATM: a two-way functional interaction in recognising and signaling DNA double strand breaks. DNA Repair (Amst.) 3, 1515-1520 (2004).
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 1515-1520
-
-
Lavin, M.F.1
-
10
-
-
0036276388
-
The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
-
D'Amours, D. & Jackson, S. P. The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nature Rev. Mol. Cell Biol. 3, 317-327 (2002).
-
(2002)
Nature Rev. Mol. Cell Biol
, vol.3
, pp. 317-327
-
-
D'Amours, D.1
Jackson, S.P.2
-
11
-
-
0032502782
-
Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif
-
Schaeper, U., Subramanian, T., Lim, L., Boyd, J. M. & Chinnadurai, G. Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif. J. Biol. Chem. 273, 8549-8552 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 8549-8552
-
-
Schaeper, U.1
Subramanian, T.2
Lim, L.3
Boyd, J.M.4
Chinnadurai, G.5
-
12
-
-
0032144027
-
Molecular cloning and characterization of a novel retinoblastoma-binding protein
-
Fusco, C., Reymond, A. & Zervos, A. S. Molecular cloning and characterization of a novel retinoblastoma-binding protein. Genomics 51, 351-358 (1998).
-
(1998)
Genomics
, vol.51
, pp. 351-358
-
-
Fusco, C.1
Reymond, A.2
Zervos, A.S.3
-
13
-
-
7844246154
-
Characterization of a carboxy-terminal BRCA1 interacting protein
-
Wong, A. K. C. et al. Characterization of a carboxy-terminal BRCA1 interacting protein. Oncogene 17, 2279-2285 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 2279-2285
-
-
Wong, A.K.C.1
-
14
-
-
0032566753
-
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
-
Yu, X., Wu, L. C., Bowcock, A. M., Aronheim, A. & Baer, R. The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression. J. Biol. Chem. 273, 25388-25392 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 25388-25392
-
-
Yu, X.1
Wu, L.C.2
Bowcock, A.M.3
Aronheim, A.4
Baer, R.5
-
15
-
-
29944434644
-
Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes
-
Greenberg, R. A. et al. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes Dev. 20, 34-46 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 34-46
-
-
Greenberg, R.A.1
-
16
-
-
6344264992
-
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
-
Yu, X. & Chen, J. DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains. Mol. Cell. Biol. 24, 9478-9486 (2004).
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 9478-9486
-
-
Yu, X.1
Chen, J.2
-
17
-
-
33745614048
-
BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP
-
Yu, X., Fu, S., Lai, M., Baer, R. & Chen, J. BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP. Genes Dev. 20, 1721-1726 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 1721-1726
-
-
Yu, X.1
Fu, S.2
Lai, M.3
Baer, R.4
Chen, J.5
-
18
-
-
0030759699
-
A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2
-
McKee, A. H. & Kleckner, N. A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2. Genetics 146, 797-816 (1997).
-
(1997)
Genetics
, vol.146
, pp. 797-816
-
-
McKee, A.H.1
Kleckner, N.2
-
19
-
-
0030811331
-
Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae
-
Prinz, S., Amon, A. & Klein, F. Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. Genetics 146, 781-795 (1997).
-
(1997)
Genetics
, vol.146
, pp. 781-795
-
-
Prinz, S.1
Amon, A.2
Klein, F.3
-
20
-
-
0035022013
-
Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: A role for SAE2/COM1
-
Rattray, A. J., McGill, C. B., Shafer, B. K. & Strathern, J. N. Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1. Genetics 158, 109-122 (2001).
-
(2001)
Genetics
, vol.158
, pp. 109-122
-
-
Rattray, A.J.1
McGill, C.B.2
Shafer, B.K.3
Strathern, J.N.4
-
21
-
-
0037169325
-
The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
-
Lobachev, K. S., Gordenin, D. A. & Resnick, M. A. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell 108, 183-193 (2002).
-
(2002)
Cell
, vol.108
, pp. 183-193
-
-
Lobachev, K.S.1
Gordenin, D.A.2
Resnick, M.A.3
-
22
-
-
33644691699
-
-
Clerici, M., Mantiero, D., Lucchini, G. & Longhese, M. P. The S. cerevisiae Sae2 protein promotes resection and bridging of double-strand break ends. J. Biol. Chem. 280, 38631-38638 (2005).
-
Clerici, M., Mantiero, D., Lucchini, G. & Longhese, M. P. The S. cerevisiae Sae2 protein promotes resection and bridging of double-strand break ends. J. Biol. Chem. 280, 38631-38638 (2005).
-
-
-
-
23
-
-
0025133118
-
Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons
-
D'Arpa, P., Beardmore, C. & Liu, L. F. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res. 50, 6919-6924 (1990).
-
(1990)
Cancer Res
, vol.50
, pp. 6919-6924
-
-
D'Arpa, P.1
Beardmore, C.2
Liu, L.F.3
-
24
-
-
23344444636
-
Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
-
Saleh-Gohari, N. et al. Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol. Cell. Biol. 25, 7158-7169 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 7158-7169
-
-
Saleh-Gohari, N.1
-
25
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh, Y. ATM and related protein kinases: safeguarding genome integrity. Nature Rev. Cancer 3, 155-168 (2003).
-
(2003)
Nature Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
26
-
-
3142534591
-
Initiating cellular stress responses
-
Bakkenist, C. J. & Kastan, M. B. Initiating cellular stress responses. Cell 118, 9-17 (2004).
-
(2004)
Cell
, vol.118
, pp. 9-17
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
27
-
-
33344464960
-
ATM regulates ATR chromatin loading in response to DNA double-strand breaks
-
Cuadrado, M. et al. ATM regulates ATR chromatin loading in response to DNA double-strand breaks. J. Exp. Med. 203, 297-303 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 297-303
-
-
Cuadrado, M.1
-
28
-
-
0033104517
-
Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes
-
Shao, R.-G. et al. Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes. EMBO J. 18, 1397-1406 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 1397-1406
-
-
Shao, R.-G.1
-
29
-
-
33645789832
-
Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks
-
Sakasai, R. et al. Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks. Genes Cells 11, 237-246 (2006).
-
(2006)
Genes Cells
, vol.11
, pp. 237-246
-
-
Sakasai, R.1
-
30
-
-
0037341599
-
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
-
Lukas, C., Falck, J., Bartkova, J., Bartek, J. & Lukas, J. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nature Cell Biol. 5, 255-260 (2003).
-
(2003)
Nature Cell Biol
, vol.5
, pp. 255-260
-
-
Lukas, C.1
Falck, J.2
Bartkova, J.3
Bartek, J.4
Lukas, J.5
-
31
-
-
33646117239
-
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
-
Bekker-Jensen, S. et al. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J. Cell Biol. 173, 195-206 (2006).
-
(2006)
J. Cell Biol
, vol.173
, pp. 195-206
-
-
Bekker-Jensen, S.1
-
32
-
-
18244385718
-
ATRIP binding to RPA-ssDNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation
-
Ball, H. L., Myers, J. S. & Cortez, D. ATRIP binding to RPA-ssDNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation. Mol. Biol. Cell 16, 2372-2381 (2005).
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2372-2381
-
-
Ball, H.L.1
Myers, J.S.2
Cortez, D.3
-
33
-
-
33646795891
-
Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex
-
Adams, K. E., Medhurst, A. L., Dart, D. A. & Lakin, N. D. Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex. Oncogene 25, 3894-3904 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 3894-3904
-
-
Adams, K.E.1
Medhurst, A.L.2
Dart, D.A.3
Lakin, N.D.4
-
34
-
-
33646777679
-
Rapid activation of ATR by ionizing radiation requires ATM and Mre11
-
Myers, J. S. & Cortez, D. Rapid activation of ATR by ionizing radiation requires ATM and Mre11. J. Biol. Chem. 281, 9346-9350 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, pp. 9346-9350
-
-
Myers, J.S.1
Cortez, D.2
-
35
-
-
0032085295
-
The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks
-
Pauli, T. T. & Gellert, M. The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks. Mol. Cell 1, 969-979 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 969-979
-
-
Pauli, T.T.1
Gellert, M.2
-
36
-
-
6944226229
-
MRE11/RAD50/NBS1: Complex activities
-
Assenmacher, N. & Hopfner, K. P. MRE11/RAD50/NBS1: complex activities. Chromosoma 113, 157-166 (2004).
-
(2004)
Chromosoma
, vol.113
, pp. 157-166
-
-
Assenmacher, N.1
Hopfner, K.P.2
-
37
-
-
27644524833
-
MRE11/RAD50 cleaves DNA in the AID/UNG-Dependent Pathway of immunoglobulin gene diversification
-
Larson, E. D., Cummings, W. J., Bednarski, D. W. & Maizels, N. MRE11/RAD50 cleaves DNA in the AID/UNG-Dependent Pathway of immunoglobulin gene diversification. Mol. Cell 20, 367-375 (2005).
-
(2005)
Mol. Cell
, vol.20
, pp. 367-375
-
-
Larson, E.D.1
Cummings, W.J.2
Bednarski, D.W.3
Maizels, N.4
-
38
-
-
0032555480
-
Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95
-
Trujillo, K. M., Yuan, S.-S. F., Lee, E.-Y. P. & Sung, P. Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95. J. Biol. Chem. 273, 21447-21450 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 21447-21450
-
-
Trujillo, K.M.1
Yuan, S.-S.F.2
Lee, E.-Y.P.3
Sung, P.4
-
39
-
-
0035893363
-
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
-
Pierce, A. J., Hu, P., Han, M., Ellis, N. & Jasin, M. Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev. 15, 3237-3242 (2001).
-
(2001)
Genes Dev
, vol.15
, pp. 3237-3242
-
-
Pierce, A.J.1
Hu, P.2
Han, M.3
Ellis, N.4
Jasin, M.5
-
40
-
-
0035878724
-
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements
-
Schaffer, A. A. et al. Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements. Nucleic Acids Res. 29, 2994-3005 (2001).
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 2994-3005
-
-
Schaffer, A.A.1
-
41
-
-
22144434446
-
Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae
-
Deng, C., Brown, J. A., You, D. & Brown, J. M. Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae. Genetics 170, 591-600 (2005).
-
(2005)
Genetics
, vol.170
, pp. 591-600
-
-
Deng, C.1
Brown, J.A.2
You, D.3
Brown, J.M.4
-
42
-
-
4544281398
-
Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
-
Lisby, M., Barlow, J. H., Burgess, R. C. & Rothstein, R. Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins. Cell 118, 699-713 (2004).
-
(2004)
Cell
, vol.118
, pp. 699-713
-
-
Lisby, M.1
Barlow, J.H.2
Burgess, R.C.3
Rothstein, R.4
-
43
-
-
0034644220
-
Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
-
Li, S. et al. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature 13, 210-215 (2000).
-
(2000)
Nature
, vol.13
, pp. 210-215
-
-
Li, S.1
-
44
-
-
2942594756
-
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation
-
Baroni, E., Viscardi, V., Cartagena-Lirola, H., Lucchini, G. & Longhese, M. P. The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation. Mol. Cell. Biol. 24, 4151-4165 (2004).
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 4151-4165
-
-
Baroni, E.1
Viscardi, V.2
Cartagena-Lirola, H.3
Lucchini, G.4
Longhese, M.P.5
-
45
-
-
33746225419
-
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis
-
Cartagena-Lirola, H., Guerini, I., Viscardi, V., Lucchini, G. & Longhese, M. P. Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis. Cell Cycle 5, 1549-1559 (2006).
-
(2006)
Cell Cycle
, vol.5
, pp. 1549-1559
-
-
Cartagena-Lirola, H.1
Guerini, I.2
Viscardi, V.3
Lucchini, G.4
Longhese, M.P.5
-
46
-
-
0036850764
-
Screening for microsatellite instability target genes in colorectal cancers
-
Vilkki, S. et al. Screening for microsatellite instability target genes in colorectal cancers. J. Med. Genet. 39, 785-789 (2002).
-
(2002)
J. Med. Genet
, vol.39
, pp. 785-789
-
-
Vilkki, S.1
-
47
-
-
33747837752
-
CtIP, a multivalent adaptor connecting transcriptional regulation, checkpoint control and tumor suppression
-
Wu, G. & Lee, W. H. CtIP, a multivalent adaptor connecting transcriptional regulation, checkpoint control and tumor suppression. Cell Cycle 5, 1592-1596 (2006).
-
(2006)
Cell Cycle
, vol.5
, pp. 1592-1596
-
-
Wu, G.1
Lee, W.H.2
-
48
-
-
0033514993
-
Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage
-
Raderschall, E., Golub, E. I. & Haaf, T. Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage. Proc. Natl Acad. Sci. USA 96, 1921-1926 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 1921-1926
-
-
Raderschall, E.1
Golub, E.I.2
Haaf, T.3
-
49
-
-
0042317328
-
The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin
-
Wu-Baer, F., Lagrazon, K., Yuan, W. & Baer, R. The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin. J. Biol. Chem. 278, 34743-34746 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 34743-34746
-
-
Wu-Baer, F.1
Lagrazon, K.2
Yuan, W.3
Baer, R.4
|