Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis

Current Biology

Volumn 20, Issue 18, 2010, Pages 1666-1671

  Uetake, Yumi ^a   Sluder, Greenfield ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; LEUPEPTIN; NOCODAZOLE;

ARTICLE; CELL LINE; CELL PROLIFERATION; HUMAN; METABOLISM; MITOSIS; PHYSIOLOGY; PROMETAPHASE;

ANTINEOPLASTIC AGENTS; CELL LINE; CELL PROLIFERATION; HUMANS; LEUPEPTINS; MITOSIS; NOCODAZOLE; PROMETAPHASE;

EID: 77957219796     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2010.08.018     Document Type: Article

References (30)

1. C.L. Rieder, R.W. Cole, A. Khodjakov, and G. Sluder The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores J. Cell Biol. 130 1995 941 948
2. A. Musacchio, and E.D. Salmon The spindle-assembly checkpoint in space and time Nat. Rev. Mol. Cell Biol. 8 2007 379 393
3. D.A. Brito, Z. Yang, and C.L. Rieder Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied J. Cell Biol. 182 2008 623 629
4. Z. Yang, A.E. Kenny, D.A. Brito, and C.L. Rieder Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments J. Cell Biol. 186 2009 675 684
5. D.A. Brito, and C.L. Rieder Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint Curr. Biol. 16 2006 1194 1200
6. S.M. Cross, C.A. Sanchez, C.A. Morgan, M.K. Schimke, S. Ramel, R.L. Idzerda, W.H. Raskind, and B.J. Reid A p53-dependent mouse spindle checkpoint Science 267 1995 1353 1356
7. J.S. Lanni, and T. Jacks Characterization of the p53-dependent postmitotic checkpoint following spindle disruption Mol. Cell. Biol. 18 1998 1055 1064
8. A.J. Minn, L.H. Boise, and C.B. Thompson Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage Genes Dev. 10 1996 2621 2631
9. Z.N. Demidenko, S. Kalurupalle, C. Hanko, C.U. Lim, E. Broude, and M.V. Blagosklonny Mechanism of G1-like arrest by low concentrations of paclitaxel: Next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis Oncogene 27 2008 4402 4410
10. M. Ciciarello, R. Mangiacasale, M. Casenghi, M. Zaira Limongi, M. D'Angelo, S. Soddu, P. Lavia, and E. Cundari p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle J. Biol. Chem. 276 2001 19205 19213
11. A. Tritarelli, E. Oricchio, M. Ciciarello, R. Mangiacasale, A. Palena, P. Lavia, S. Soddu, and E. Cundari p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation Mol. Biol. Cell 15 2004 3751 3757
12. P. Giannakakou, R. Robey, T. Fojo, and M.V. Blagosklonny Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: Molecular determinants of paclitaxel-induced cytotoxicity Oncogene 20 2001 3806 3813
13. D.A. Brito, and C.L. Rieder The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells Cell Motil. Cytoskeleton 66 2009 437 447
14. A.E. Ikui, C.P. Yang, T. Matsumoto, and S.B. Horwitz Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy Cell Cycle 4 2005 1385 1388
15. D.B. Hoffman, C.G. Pearson, T.J. Yen, B.J. Howell, and E.D. Salmon Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores Mol. Biol. Cell 12 2001 1995 2009
16. A.G. Ehrhardt, and G. Sluder Spindle pole fragmentation due to proteasome inhibition J. Cell. Physiol. 204 2005 808 818
17. E.P. Rogakou, D.R. Pilch, A.H. Orr, V.S. Ivanova, and W.M. Bonner DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 J. Biol. Chem. 273 1998 5858 5868
18. W.B. Dalton, M.O. Nandan, R.T. Moore, and V.W. Yang Human cancer cells commonly acquire DNA damage during mitotic arrest Cancer Res. 67 2007 11487 11492
19. F. Quignon, L. Rozier, A.M. Lachages, A. Bieth, M. Simili, and M. Debatisse Sustained mitotic block elicits DNA breaks: One-step alteration of ploidy and chromosome integrity in mammalian cells Oncogene 26 2007 165 172
20. Y. Ichijima, R. Sakasai, N. Okita, K. Asahina, S. Mizutani, and H. Teraoka Phosphorylation of histone H2AX at M phase in human cells without DNA damage response Biochem. Biophys. Res. Commun. 336 2005 807 812
21. S.L. Thompson, and D.A. Compton Examining the link between chromosomal instability and aneuploidy in human cells J. Cell Biol. 180 2008 665 672
22. D. Cimini, B. Howell, P. Maddox, A. Khodjakov, F. Degrassi, and E.D. Salmon Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells J. Cell Biol. 153 2001 517 527
23. S.L. Thompson, and D.A. Compton Proliferation of aneuploid human cells is limited by a p53-dependent mechanism J. Cell Biol. 188 2010 369 381
24. M.V. Blagosklonny Prolonged mitosis versus tetraploid checkpoint: How p53 measures the duration of mitosis Cell Cycle 5 2006 971 975
25. M.V. Blagosklonny Mitotic arrest and cell fate: Why and how mitotic inhibition of transcription drives mutually exclusive events Cell Cycle 6 2007 70 74
26. J.C. Lee, S. Kumar, D.E. Griswold, D.C. Underwood, B.J. Votta, and J.L. Adams Inhibition of p38 MAP kinase as a therapeutic strategy Immunopharmacology 47 2000 185 201
27. C.L. Rieder, and R. Cole Microtubule disassembly delays the G2-M transition in vertebrates Curr. Biol. 10 2000 1067 1070
28. C.L. Rieder, and H. Maiato Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint Dev. Cell 7 2004 637 651
29. Y. Uetake, J. Loncarek, J.J. Nordberg, C.N. English, S. La Terra, A. Khodjakov, and G. Sluder Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells J. Cell Biol. 176 2007 173 182
30. Y. Uetake, and G. Sluder Cell-cycle progression without an intact microtuble cytoskeleton Curr. Biol. 17 2007 2081 2086