Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

Molecular Cell

Volumn 6, Issue 4, 2000, Pages 839-849

  Kumagai, Akiko ^a   Dunphy, William G ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; OLIGONUCLEOTIDE; PROTEIN DERIVATIVE; TAUTOMYCIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA REPLICATION; DNA TEMPLATE; EGG; EXTRACT; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; XENOPUS;

ANIMALIA;

EID: 0033634679     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(05)00092-4     Document Type: Article

References (35)

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2. ATR disruption leads to chromosomal fragmentation and early embryonic lethality
3. The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts
4. Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: Studies in Xenopus
5. Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
6. RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation
7. Cell cycle checkpoints: Preventing an identity crisis
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9. Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
10. A novel protein phosphatase inhibitor, tautomycin. Effect on smooth muscle
11. Substrate specificities and identification of putative substrates of ATM kinase family members
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13. Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25
14. The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts
15. Exercising self-restraint: Discouraging illicit acts of S and M in eukaryotes
16. Protein phosphatase 2A is required for the initiation of chromosomal DNA replication
17. S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe
18. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M) DNA damage checkpoint
19. DNA damage checkpoint in budding yeast
20. Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein
21. Cell cycle regulation of the replication licensing system: Involvement of a Cdk-dependent inhibitor
22. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
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24. Cell cycle regulation of a Xenopus Wee1-like kinase
25. Cell cycle extracts
26. The G2-phase DNA-damage checkpoint
27. Protein-protein interactions define specificity in signal transduction
28. Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1
29. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
30. Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
31. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint
32. Rad-dependent response of the Chk1-encoded protein kinase at the DNA damage checkpoint
33. Isolation and characterization of the Schizosaccharomyces pombe Rhp9 gene: A gene required for the DNA damage checkpoint but not the replication checkpoint
34. Maintenance of G2 arrest in the Xenopus oocyte: A role for 14-3-3-mediated inhibition of Cdc25 nuclear import
35. DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding