SCFβTrCP-Mediated Degradation of Claspin Regulates Recovery from the DNA Replication Checkpoint Response

Molecular Cell

Volumn 23, Issue 3, 2006, Pages 319-329

  Peschiaroli, Angelo ^a   Dorrello, N Valerio ^a   Guardavaccaro, Daniele ^a   Venere, Monica ^b   Halazonetis, Thanos ^b   Sherman, Nicholas E ^c   Pagano, Michele ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

CELLCYCLE; DNA; PROTEINS

Indexed keywords

ADAPTOR PROTEIN; CLASPIN; CYCLIN DEPENDENT KINASE; DNA; MUTANT PROTEIN; SKP1 CUL1 F BOX PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; CLSPN PROTEIN, HUMAN; HISTONE; HYDROXYUREA; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; UBIQUITIN;

ANIMAL CELL; ARTICLE; CELL CYCLE REGULATION; CONTROLLED STUDY; DNA REPLICATION; EMBRYO; HUMAN; HUMAN CELL; MITOSIS; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; AMINO ACID SEQUENCE; BINDING SITE; BIOLOGICAL MODEL; CELL CYCLE; CELL LINE; DNA DAMAGE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; RADIATION EXPOSURE; SEQUENCE HOMOLOGY; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; BINDING SITES; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL LINE, TUMOR; DNA DAMAGE; DNA REPLICATION; HISTONES; HUMANS; HYDROXYUREA; MODELS, BIOLOGICAL; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY, AMINO ACID; SKP CULLIN F-BOX PROTEIN LIGASES; TRANSFECTION; UBIQUITIN; ULTRAVIOLET RAYS;

EID: 33746413746     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2006.06.013     Document Type: Article

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