A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex

Nature Chemical Biology

Volumn 4, Issue 2, 2008, Pages 119-125

  Dupré, Aude ^a,e   Boyer Chatenet, Louise ^a,f   Sattler, Rose M ^a   Modi, Ami P ^a   Lee, Ji Hoon ^b   Nicolette, Matthew L ^b   Kopelovich, Levy ^c   Jasin, Maria ^d   Baer, Richard ^a   Paull, Tanya T ^b   Gautier, Jean ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e CNRS   (France)

^f Service de Cardiologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

6 (4 HYDROXYPHENYL) 2 THIOXO 2,3 DIHYDRO 4(1H)PYRIMIDINONE; EXONUCLEASE; MIRIN; MRE11 PROTEIN; NIBRIN; PYRIMIDINONE DERIVATIVE; RAD50 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL VIABILITY; CHEMOSENSITIZATION; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENETIC SCREENING; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIZATION;

MAMMALIA;

EID: 38349008365     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.63     Document Type: Article

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