Cdc2 phosphorylation of Crb2 is required for reestablishing cell cycle progression after the damage checkpoint

Molecular Cell

Volumn 4, Issue 2, 1999, Pages 167-174

  Esashi, Fumiko ^a   Yanagida, Mitsuhiro ^a,b  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; PHOSPHOPEPTIDE; PHOSPHOPROTEIN; PROTEIN KINASE;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE; CELL REGENERATION; DNA DAMAGE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOSIS; NONHUMAN; PHOSPHORYLATION; ULTRAVIOLET RADIATION; YEAST CELL;

EID: 0033179985     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80364-0     Document Type: Article

References (32)

1. Banin, S., Moyal, L., Shieh, S., Taya, Y., Anderson, C.W., Chessa, L, Smorodinsky, N.I., Prives, C., Reiss, Y., Shiloh, Y., and Ziv, Y. (1998). Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281, 1674-1677.
2. Bentley, N., Holtzman, D., Flaggs, G., Keegan, K., DeMaggio, A., Ford, J., Hoekstra, M., and Carr, A. (1996). The Schizosaccharomyces pombe rad3 checkpoint gene. EMBO J. 15, 6641-6651.
3. Bork, P., Hoffmann, K., Bucher, P., Neuwald, A.F., Altschul, S.F., and Koonin, E.V. (1997). A superfamily of conserved domains in DNA damage responsive cell cycle checkpoint proteins. FASEB J. 11, 68-76.
4. Callaebaut, I., and Mornon, J.P. (1997). From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair. FEBS Lett. 400, 25-30.
5. Canman, C.E., Lim., D.S., Cimprich, K.A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M.B., and Siliciano, J.D. (1998). Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281, 1677-1679.
6. Emil, A. (1998). MEC1-dependent phosphorylation of Rad9p in response to DNA damage. Mol. Cell 2, 183-189.
7. Furnari, B., Rhind, N., and Russell, P. (1997). Cdc25 mitotic inducer targeted by chkl DNA damage checkpoint kinase. Science 277, 1495-1497.
8. + gene in fission yeast. Mol. Gen. Genet. 260, 522-534.
9. Henchoz, S., Chi, Y., Catarin, B., Herskowitz, I., Deshaies, R.J., and Peter, M. (1997). Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev. 11, 3046-3060.
10. Hiraoka, Y., Toda, T., and Yanagida, M. (1984). The NDA3 gene of fission yeast encodes β-tubulin: A cold sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis. Cell 39, 349-358.
11. Kumada, K., Nakamura, T., Nagao, K., Funabiki, H., Nakagawa, T., and Yanagida, M. (1998). Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis. Curr. Biol. 8, 633-641.
12. Kusubata, M., Tokui, T., Matsuoka, Y., Okumura, E., Tachibana, K., Hisanaga, S., Kishimoto, T., Yasuda, H., Kamijo, M., Ohba, Y., et al. (1992). p13suc1 suppresses the catalytic function of p34cdc2 kinase for intermediate filament proteins, in vitro. J. Biol. Chem. 267, 20937-20942.
13. Lindsay, H.D., Griffiths, D.J., Edwards, R.J., Christensen, P.U., Murray, J.M., Osman, F., Walworth, N., and Carr, A.M. (1998). S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes Dev. 12, 382-395.
14. Matsuoka, S., Huang, M., and Elledge, S.J. (1998). Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282, 1893-1897.
15. Maundrell, K. (1990). nmt1 of fission yeast. J. Biol. Chem. 265, 10857-10864.
16. McCready, S., Carr, A.M., and Lehmann, A.R. (1993). Repair of cyclobutane pyrimidine dimers and 6-4 photoproducts in the fission yeast Schizosaccharomyces pombe. Mol. Microbiol. 10, 885-890.
17. McCready, S., and Cox, B. (1993). Repair of 6-4 photoproducts in Saccharomyces cerevisiae. Mutat. Res. 293, 233-240.
18. Moreno, S., Hayles, J., and Nurse, P. (1989). Regulation of p34cdc2 protein kinase during mitosis. Cell 58, 361-372.
19. Murakami, H., and Okayama, H. (1995). A kinase from fission yeast responsible for blocking mitosis in S-phase. Nature 374, 817-819.
20. Oehlen, L.J., and Cross, F.R. (1994). G1 cyclins CLN1 and CLN2 repress the mating factor response pathway at start in the yeast cell cycle. Genes Dev. 8, 1058-1070.
21. Peter, M., and Herskowitz, I. (1994). Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1. Science 265, 1228-1231.
22. Rhind, N., Furnari, B., and Russell, P. (1997). Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast. Genes Dev. 11, 504-511.
23. Russell, P. (1998). Checkpoints on the road to mitosis. Trends Biochem. Sci. 23, 399-402.
24. +. Cell 74, 383-393.
25. Saka, Y., Esashi, F., Matsusaka, T., Mochida, S., and Yanagida, M. (1997). Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT-motif, with Cut5 and Chk1. Genes Dev. 11, 3387-3400.
26. Sun, Z., Hsiao, J., Fay, D.S., and Stern, D.F. (1998). Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint. Science 281, 272-274.
27. Su, S.S., Tanaka, Y., Samejima, I., Tanaka, K., and Yanagida, M. (1996). A nitrogen starvation-induced dormant G0 state in fission yeast: The establishment from uncommitted G1 state and its delay for return to proliferation. J. Cell Sci. 109, 1347-1357.
28. Toczyski, D.P., Galgoczy, D.J., and Hartwell, L.H. (1997). CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell 90, 1097-1106.
29. Vialard, J.E., Gilbert, C.S., Green, C.M., and Lowndes, N.F. (1998). The budding yeast Rad9 checkpoint protein is subjected to Mec1/ Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage. EMBO J. 17, 5679-5688.
30. Walworth, N.C., and Bernards, R. (1996). Rad-dependent response of the chkl -encoded protein kinase at the damage checkpoint. Science 271, 353-356.
31. Weinert, T. (1998). DNA damage and checkpoint pathways: Molecular anatomy and interactions with repair. Cell 94, 555-558.
32. Wilson, J., Wilson, S., Warr, N., and Watts, F.Z. (1997). Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: A gene required for the DNA damage checkpoint but not the replication checkpoint. Nucleic Acids Res. 25, 2138-2145.