An atlas and functional analysis of G-protein coupled receptors in human islets of Langerhans

Pharmacology and Therapeutics

Volumn 139, Issue 3, 2013, Pages 359-391

  Amisten, Stefan ^a   Salehi, Albert ^b   Rorsman, Patrik ^c   Jones, Peter M ^a   Persaud, Shanta J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b LUND UNIVERSITY   (Sweden)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

G protein coupled receptors; GPCR drug targets; GPCRome; Human islets of Langerhans; Islet hormone secretion

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; ADENOSINE RECEPTOR; ADRENERGIC RECEPTOR; ANAPHYLATOXIN; ANGIOTENSIN 1 RECEPTOR; APELIN RECEPTOR; BETA ALANINE; BILE ACID; BOMBESIN RECEPTOR; BRADYKININ RECEPTOR; CALCITONIN RECEPTOR; CALCIUM SENSING RECEPTOR; CANNABINOID RECEPTOR; CHEMERIN; CHEMOKINE RECEPTOR; CHOLECYSTOKININ RECEPTOR; COLLAGEN RECEPTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; DOPAMINE RECEPTOR; ENDOTHELIN RECEPTOR; FATTY ACID; FORMYLPEPTIDE RECEPTOR; FRIZZLED PROTEIN; G PROTEIN COUPLED RECEPTOR; GALANIN RECEPTOR; GLUCAGON; INSULIN; LIGAND; SOMATOSTATIN;

GLUCAGON RELEASE; HUMAN; INSULIN RELEASE; MACROMOLECULE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; SOMATOSTATIN RELEASE; WNT SIGNALING PATHWAY;

G-PROTEIN COUPLED RECEPTORS; GPCR DRUG TARGETS; GPCROME; HUMAN ISLETS OF LANGERHANS; ISLET HORMONE SECRETION;

ANIMALS; DIABETES MELLITUS, TYPE 2; DRUG DESIGN; DRUG INTERACTIONS; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; ISLETS OF LANGERHANS; LIGANDS; MOLECULAR TARGETED THERAPY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84881264051     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.05.004     Document Type: Review

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