The steroid glycoside H.g.-12 from Hoodia gordonii activates the human bitter receptor TAS2R14 and induces CCK release from HuTu-80 cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 299, Issue 6, 2010, Pages

  Nevé, Boris Le ^a   Foltz, Martin ^b   Daniel, Hannelore ^a   Gouka, Robin ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

Cholecystokinin receptor 1; HuTu 80; Nutrient sensing; Satiety

Indexed keywords

CALCIUM ION; CHOLECYSTOKININ; G PROTEIN COUPLED RECEPTOR; PLANT EXTRACT; PLANT GLYCOSIDE; RECEPTOR SUBTYPE; STEROID GLYCOSIDE HG12; TAS2 RECEPTOR 14; TAS2 RECEPTOR 7; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOCYNACEAE; ARTICLE; BITTER TASTE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENDOCRINE CELL; EX VIVO STUDY; GASTROINTESTINAL TRACT; HOODIA GORDONII; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE CELL; INTESTINE WALL; MALE; MOUSE; NERVE ENDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; VAGUS NERVE;

ANIMALS; APOCYNACEAE; APPETITE DEPRESSANTS; CELL LINE; CHOLECYSTOKININ; CRICETINAE; HUMANS; INTESTINES; MOLECULAR STRUCTURE; RATS; RECEPTORS, G-PROTEIN-COUPLED; SAPONINS; SINCALIDE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78649725182     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00135.2010     Document Type: Article

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