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Volumn 294, Issue 1, 2008, Pages

GABAB receptors and glucose homeostasis: Evaluation in GABA B receptor knockout mice

Author keywords

aminobutyric acid; Glycemia; Insulin; Pancreas histology

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; BACLOFEN; GLUCOSE; INSULIN; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; GABA TYPE B RECEPTOR, SUBUNIT 1; UNCLASSIFIED DRUG;

EID: 38349016310     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00615.2006     Document Type: Article
Times cited : (38)

References (62)
  • 1
    • 0031768322 scopus 로고    scopus 로고
    • Homo-Delarche F. Glucose homeostasis in the nonobese diabetic mouse at the prediabetic stage
    • Amrani A, Durant S, Throsby M, Coulaud J, Dardenne M, Homo-Delarche F. Glucose homeostasis in the nonobese diabetic mouse at the prediabetic stage. Endocrinology 139: 1115-1124, 1998.
    • (1998) Endocrinology , vol.139 , pp. 1115-1124
    • Amrani, A.1    Durant, S.2    Throsby, M.3    Coulaud, J.4    Dardenne, M.5
  • 2
    • 31444432477 scopus 로고    scopus 로고
    • Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes
    • Asghar Z, Yau D, Chan F, Leroith D, Chan CB, Wheeler MB. Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes. Diabetologia 49: 90-99, 2006.
    • (2006) Diabetologia , vol.49 , pp. 90-99
    • Asghar, Z.1    Yau, D.2    Chan, F.3    Leroith, D.4    Chan, C.B.5    Wheeler, M.B.6
  • 3
    • 3042546515 scopus 로고    scopus 로고
    • Molecular structure and physiological functions of GABA(B) receptors
    • Bettler B, Kaupmann K, Mosbacher J, Gassmann M. Molecular structure and physiological functions of GABA(B) receptors. Physiol Rev 84: 835-867, 2004.
    • (2004) Physiol Rev , vol.84 , pp. 835-867
    • Bettler, B.1    Kaupmann, K.2    Mosbacher, J.3    Gassmann, M.4
  • 4
    • 33646529626 scopus 로고    scopus 로고
    • Molecular diversity, trafficking and subcellular localization of GABA(B) receptors
    • Bettler B, Tiao JY. Molecular diversity, trafficking and subcellular localization of GABA(B) receptors. Pharmacol Ther 110: 533-543, 2006.
    • (2006) Pharmacol Ther , vol.110 , pp. 533-543
    • Bettler, B.1    Tiao, J.Y.2
  • 6
    • 28444454478 scopus 로고    scopus 로고
    • Expression of gamma-aminobutyric acid B receptor subunits in hypothalamus of male and female developing rats
    • Bianchi MS, Lux-Lantos VA, Bettler B, Libertun C. Expression of gamma-aminobutyric acid B receptor subunits in hypothalamus of male and female developing rats. Brain Res Dev Brain Res 160: 124-129, 2005.
    • (2005) Brain Res Dev Brain Res , vol.160 , pp. 124-129
    • Bianchi, M.S.1    Lux-Lantos, V.A.2    Bettler, B.3    Libertun, C.4
  • 7
    • 30844468174 scopus 로고    scopus 로고
    • GABAB receptor: A site of therapeutic benefit
    • Bowery NG. GABAB receptor: a site of therapeutic benefit. Curr Opin Pharmacol 6: 37-43, 2006.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 37-43
    • Bowery, N.G.1
  • 9
    • 4644278226 scopus 로고    scopus 로고
    • GABAB receptor activation inhibits exocytosis in rat pancreatic beta-cells by G-protein-dependent activation of calcineurin
    • Braun M, Wendt A, Buschard K, Salehi A, Sewing S, Gromada J, Rorsman P. GABAB receptor activation inhibits exocytosis in rat pancreatic beta-cells by G-protein-dependent activation of calcineurin. J Physiol 559: 397-409, 2004.
    • (2004) J Physiol , vol.559 , pp. 397-409
    • Braun, M.1    Wendt, A.2    Buschard, K.3    Salehi, A.4    Sewing, S.5    Gromada, J.6    Rorsman, P.7
  • 10
    • 4344581494 scopus 로고    scopus 로고
    • Distinctive roles for prolactin and growth hormone in the activation of signal transducer and activator of transcription 5 in pancreatic islets of langerhans
    • Brelje TC, Stout LE, Bhagroo NV, Sorenson RL. Distinctive roles for prolactin and growth hormone in the activation of signal transducer and activator of transcription 5 in pancreatic islets of langerhans. Endocrinology 145: 4162-4175, 2004.
    • (2004) Endocrinology , vol.145 , pp. 4162-4175
    • Brelje, T.C.1    Stout, L.E.2    Bhagroo, N.V.3    Sorenson, R.L.4
  • 11
    • 0036190005 scopus 로고    scopus 로고
    • Metabotropic glutamate and GABA(B) receptors contribute to the modulation of glucose-stimulated insulin secretion in pancreatic beta cells
    • Brice NL, Varadi A, Aschcroft SJ, Molnar E. Metabotropic glutamate and GABA(B) receptors contribute to the modulation of glucose-stimulated insulin secretion in pancreatic beta cells. Diabetologia 45: 242-252, 2002.
    • (2002) Diabetologia , vol.45 , pp. 242-252
    • Brice, N.L.1    Varadi, A.2    Aschcroft, S.J.3    Molnar, E.4
  • 13
    • 0036263217 scopus 로고    scopus 로고
    • Expression of the vesicular inhibitory amino acid transporter in pancreatic islet cells: Distribution of the transporter within rat islets
    • Chessler SD, Simonson WT, Sweet IR, Hammerle LP. Expression of the vesicular inhibitory amino acid transporter in pancreatic islet cells: distribution of the transporter within rat islets. Diabetes 51: 1763-1771, 2002.
    • (2002) Diabetes , vol.51 , pp. 1763-1771
    • Chessler, S.D.1    Simonson, W.T.2    Sweet, I.R.3    Hammerle, L.P.4
  • 15
    • 1442334215 scopus 로고    scopus 로고
    • GABA in the endocrine pancreas: Its putative role as an islet cell paracrine-signalling molecule
    • Franklin IK, Wollheim CB. GABA in the endocrine pancreas: its putative role as an islet cell paracrine-signalling molecule. J Gen Physiol 123: 185-190, 2004.
    • (2004) J Gen Physiol , vol.123 , pp. 185-190
    • Franklin, I.K.1    Wollheim, C.B.2
  • 19
    • 0025787665 scopus 로고
    • The influence of gamma-aminobutyric acid on hormone release by mouse and rat endocrine pancreas
    • Gilon P, Bertrand G, Loubatieres-Mariani MM, Remacle C, Henquin JC. The influence of gamma-aminobutyric acid on hormone release by mouse and rat endocrine pancreas. Endocrinology 129: 2521-2529, 1991.
    • (1991) Endocrinology , vol.129 , pp. 2521-2529
    • Gilon, P.1    Bertrand, G.2    Loubatieres-Mariani, M.M.3    Remacle, C.4    Henquin, J.C.5
  • 21
    • 0032882751 scopus 로고    scopus 로고
    • GABA agonists differentially modify blood glucose levels of diabetic rats
    • Gomez R, Asnis N, Tannhauser SL, Barros HM. GABA agonists differentially modify blood glucose levels of diabetic rats. Jpn J Pharmacol 80: 327-331, 1999.
    • (1999) Jpn J Pharmacol , vol.80 , pp. 327-331
    • Gomez, R.1    Asnis, N.2    Tannhauser, S.L.3    Barros, H.M.4
  • 22
    • 3042636409 scopus 로고    scopus 로고
    • Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1
    • Goren HJ, Kulkarni RN, Kahn CR. Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1. Endocrinology 145: 3307-3323, 2004.
    • (2004) Endocrinology , vol.145 , pp. 3307-3323
    • Goren, H.J.1    Kulkarni, R.N.2    Kahn, C.R.3
  • 23
    • 0027411109 scopus 로고
    • Suppressive effect of GABA on insulin secretion from the pancreatic beta-cells in the rat
    • Gu XH, Kurose T, Kato S, Masuda K, Tsuda K, Ishida H, Seino Y. Suppressive effect of GABA on insulin secretion from the pancreatic beta-cells in the rat. Life Sci 52: 687-694, 1993.
    • (1993) Life Sci , vol.52 , pp. 687-694
    • Gu, X.H.1    Kurose, T.2    Kato, S.3    Masuda, K.4    Tsuda, K.5    Ishida, H.6    Seino, Y.7
  • 25
    • 0037449745 scopus 로고    scopus 로고
    • Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islets of Langerhans
    • Hayashi M, Yamada H, Uehara S, Morimoto R, Muroyama A, Yatsushiro S, Takeda J, Yamamoto A, Moriyama Y. Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islets of Langerhans. J Biol Chem 278: 1966-1974, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 1966-1974
    • Hayashi, M.1    Yamada, H.2    Uehara, S.3    Morimoto, R.4    Muroyama, A.5    Yatsushiro, S.6    Takeda, J.7    Yamamoto, A.8    Moriyama, Y.9
  • 26
    • 0345222443 scopus 로고    scopus 로고
    • Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice
    • Hill DJ, Petrik J, Arany E, McDonald TJ, Delovitch TL. Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice. J Endocrinol 161: 153-165, 1999.
    • (1999) J Endocrinol , vol.161 , pp. 153-165
    • Hill, D.J.1    Petrik, J.2    Arany, E.3    McDonald, T.J.4    Delovitch, T.L.5
  • 27
    • 0034463880 scopus 로고    scopus 로고
    • Increased and persistent circulating insulin-like growth factor II in neonatal transgenic mice suppresses developmental apoptosis in the pancreatic islets
    • Hill DJ, Strutt B, Arany E, Zaina S, Coukell S, Graham CF. Increased and persistent circulating insulin-like growth factor II in neonatal transgenic mice suppresses developmental apoptosis in the pancreatic islets. Endocrinology 141: 1151-1157, 2000.
    • (2000) Endocrinology , vol.141 , pp. 1151-1157
    • Hill, D.J.1    Strutt, B.2    Arany, E.3    Zaina, S.4    Coukell, S.5    Graham, C.F.6
  • 28
    • 33751169830 scopus 로고    scopus 로고
    • GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice
    • Jacobson LH, Bettler B, Kaupmann K, Cryan JF. GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice. J Pharmacol Exp Ther 319: 1317-1326, 2006.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 1317-1326
    • Jacobson, L.H.1    Bettler, B.2    Kaupmann, K.3    Cryan, J.F.4
  • 29
    • 0013522709 scopus 로고    scopus 로고
    • Homo-Delarche F, Dardenne M, Drexhage HA. Effect of prophylactic insulin treatment on the number of ER-MP23+ macrophages in the pancreas of NOD mice. Is the prevention of diabetes based on beta-cell rest?
    • Jansen A, Rosmalen JG, Homo-Delarche F, Dardenne M, Drexhage HA. Effect of prophylactic insulin treatment on the number of ER-MP23+ macrophages in the pancreas of NOD mice. Is the prevention of diabetes based on beta-cell rest? J Autoimmun 9: 341-348, 1996.
    • (1996) J Autoimmun , vol.9 , pp. 341-348
    • Jansen, A.1    Rosmalen, J.G.2
  • 30
    • 27644554369 scopus 로고    scopus 로고
    • The gamma-aminobutyric acid A receptor pi subunit is overexpressed in pancreatic adenocarcinomas
    • Johnson SK, Haun RS. The gamma-aminobutyric acid A receptor pi subunit is overexpressed in pancreatic adenocarcinomas. JOP 6: 136-142, 2005.
    • (2005) JOP , vol.6 , pp. 136-142
    • Johnson, S.K.1    Haun, R.S.2
  • 33
    • 0033524937 scopus 로고    scopus 로고
    • Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes
    • Kulkarni RN, Bruning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 96: 329-339, 1999.
    • (1999) Cell , vol.96 , pp. 329-339
    • Kulkarni, R.N.1    Bruning, J.C.2    Winnay, J.N.3    Postic, C.4    Magnuson, M.A.5    Kahn, C.R.6
  • 35
    • 14644419552 scopus 로고    scopus 로고
    • Regulated exocytosis and kiss-and-run of synaptic-like microvesicles in INS-1 and primary rat beta-cells
    • MacDonald PE, Obermüller S, Vikman J, Galvanovskis J, Rorsman P, Eliasson L. Regulated exocytosis and kiss-and-run of synaptic-like microvesicles in INS-1 and primary rat beta-cells. Diabetes 54: 736-743, 2005.
    • (2005) Diabetes , vol.54 , pp. 736-743
    • MacDonald, P.E.1    Obermüller, S.2    Vikman, J.3    Galvanovskis, J.4    Rorsman, P.5    Eliasson, L.6
  • 36
    • 0033558937 scopus 로고    scopus 로고
    • Immunohistochemical localization of GABA(B) receptors in the rat central nervous system
    • Margeta-Mitrovic M, Mitrovic I, Riley RC, Jan LY, Basbaum AI. Immunohistochemical localization of GABA(B) receptors in the rat central nervous system. J Comp Neurol 405: 299-321, 1999.
    • (1999) J Comp Neurol , vol.405 , pp. 299-321
    • Margeta-Mitrovic, M.1    Mitrovic, I.2    Riley, R.C.3    Jan, L.Y.4    Basbaum, A.I.5
  • 37
    • 0027197584 scopus 로고
    • GABA production in rat islets of Langerhans
    • Michalik M, Nelson J, Erecinska M. GABA production in rat islets of Langerhans. Diabetes 42: 1506-1513, 1993.
    • (1993) Diabetes , vol.42 , pp. 1506-1513
    • Michalik, M.1    Nelson, J.2    Erecinska, M.3
  • 38
    • 0141987898 scopus 로고    scopus 로고
    • Glutamate-mediated signaling in the islets of Langerhans: A thread entangled
    • Moriyama Y, Hayashi M. Glutamate-mediated signaling in the islets of Langerhans: a thread entangled. Trends Pharmacol Sci 24: 511-517, 2003.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 511-517
    • Moriyama, Y.1    Hayashi, M.2
  • 39
    • 0021866489 scopus 로고
    • Hyperinsulinaemia and insulin insensitivity: Studies in subjects with insulinoma
    • Nankervis A, Proietto J, Aitken P, Alford F. Hyperinsulinaemia and insulin insensitivity: studies in subjects with insulinoma. Diabetologia 28: 427-431, 1985.
    • (1985) Diabetologia , vol.28 , pp. 427-431
    • Nankervis, A.1    Proietto, J.2    Aitken, P.3    Alford, F.4
  • 43
    • 33744545030 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid secreted from islet beta-cells modulates exocrine secretion in rat pancreas
    • Park YD, Cui ZY, Wu G, Park HS, Park HJ. Gamma-aminobutyric acid secreted from islet beta-cells modulates exocrine secretion in rat pancreas. World J Gastroenterol 12: 3026-3030, 2006.
    • (2006) World J Gastroenterol , vol.12 , pp. 3026-3030
    • Park, Y.D.1    Cui, Z.Y.2    Wu, G.3    Park, H.S.4    Park, H.J.5
  • 44
    • 0031788728 scopus 로고    scopus 로고
    • Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor
    • Petrik J, Arany E, McDonald TJ, Hill DJ. Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor. Endocrinology 139: 2994-3004, 1998.
    • (1998) Endocrinology , vol.139 , pp. 2994-3004
    • Petrik, J.1    Arany, E.2    McDonald, T.J.3    Hill, D.J.4
  • 45
    • 0033323812 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia
    • Petrik J, Pell JM, Arany E, McDonald TJ, Dean WL, Reik W, Hill DJ. Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia. Endocrinology 140: 2353-2363, 1999.
    • (1999) Endocrinology , vol.140 , pp. 2353-2363
    • Petrik, J.1    Pell, J.M.2    Arany, E.3    McDonald, T.J.4    Dean, W.L.5    Reik, W.6    Hill, D.J.7
  • 46
    • 33744523655 scopus 로고    scopus 로고
    • Adenohypophyseal and hypothalamic GABA B receptor subunits are downregulated by estradiol in adult female rats
    • Rey-Roldan EB, Bianchi MS, Bettler B, Becu-Villalobos D, Lux-Lantos VA, Libertun C. Adenohypophyseal and hypothalamic GABA B receptor subunits are downregulated by estradiol in adult female rats. Life Sci 79: 342-350, 2006.
    • (2006) Life Sci , vol.79 , pp. 342-350
    • Rey-Roldan, E.B.1    Bianchi, M.S.2    Bettler, B.3    Becu-Villalobos, D.4    Lux-Lantos, V.A.5    Libertun, C.6
  • 47
    • 0019402937 scopus 로고
    • Effect of muscimol on glucose-stimulated somatostatin and insulin release from the isolated, perfused rat pancreas
    • Robbins MS, Grouse LH, Sorenson RL, Elde RP. Effect of muscimol on glucose-stimulated somatostatin and insulin release from the isolated, perfused rat pancreas. Diabetes 30: 168-171, 1981.
    • (1981) Diabetes , vol.30 , pp. 168-171
    • Robbins, M.S.1    Grouse, L.H.2    Sorenson, R.L.3    Elde, R.P.4
  • 48
  • 50
    • 25844489095 scopus 로고    scopus 로고
    • Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA(B) receptors
    • Sauter K, Grampp T, Fritschy JM, Kaupmann K, Bettler B, Mohler H, Benke D. Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA(B) receptors. J Biol Chem 280: 33566-33572, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 33566-33572
    • Sauter, K.1    Grampp, T.2    Fritschy, J.M.3    Kaupmann, K.4    Bettler, B.5    Mohler, H.6    Benke, D.7
  • 51
    • 0030070611 scopus 로고    scopus 로고
    • Chronic primary hyperinsulinaemia is associated with altered insulin receptor mRNA splicing in muscle of patients with insulinoma
    • Sbraccia P, D'Adamo M, Leonetti F, Caiola S, Iozzo P, Giaccari A, Buongiorno A, Tamburrano G. Chronic primary hyperinsulinaemia is associated with altered insulin receptor mRNA splicing in muscle of patients with insulinoma. Diabetologia 39: 220-225, 1996.
    • (1996) Diabetologia , vol.39 , pp. 220-225
    • Sbraccia, P.1    D'Adamo, M.2    Leonetti, F.3    Caiola, S.4    Iozzo, P.5    Giaccari, A.6    Buongiorno, A.7    Tamburrano, G.8
  • 54
    • 0029856092 scopus 로고    scopus 로고
    • Comparison of insulin sensitivity in patients with insulinoma and obese Type 2 diabetes mellitus
    • Skrha J, Sindelka G, Haas T, Hilgertova J, Justova V. Comparison of insulin sensitivity in patients with insulinoma and obese Type 2 diabetes mellitus. Horm Metab Res 28: 595-598, 1996.
    • (1996) Horm Metab Res , vol.28 , pp. 595-598
    • Skrha, J.1    Sindelka, G.2    Haas, T.3    Hilgertova, J.4    Justova, V.5
  • 55
    • 0025945011 scopus 로고
    • Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves
    • Sorenson RL, Garry DG, Brelje TC. Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves. Diabetes 40: 1365-1374, 1991.
    • (1991) Diabetes , vol.40 , pp. 1365-1374
    • Sorenson, R.L.1    Garry, D.G.2    Brelje, T.C.3
  • 57
    • 33745837448 scopus 로고    scopus 로고
    • GABA(B) receptor-mediated modulation of glutamate signaling in cerebellar Purkinje cells
    • Tabata T, Kano M. GABA(B) receptor-mediated modulation of glutamate signaling in cerebellar Purkinje cells. Cerebellum 5: 127-133, 2006.
    • (2006) Cerebellum , vol.5 , pp. 127-133
    • Tabata, T.1    Kano, M.2
  • 58
    • 0028014432 scopus 로고
    • A role for synaptic vesicles in non-neuronal cells: Clues from pancreatic beta cells and from chromaffin cells
    • Thomas-Reetz AC, De Camilli P. A role for synaptic vesicles in non-neuronal cells: clues from pancreatic beta cells and from chromaffin cells. FASEB J 8: 209-216, 1994.
    • (1994) FASEB J , vol.8 , pp. 209-216
    • Thomas-Reetz, A.C.1    De Camilli, P.2
  • 60
    • 1842422955 scopus 로고    scopus 로고
    • Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells
    • Wendt A, Birnir B, Buschard K, Gromada J, Salehi A, Sewing S, Rorsman P, Braun M. Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells. Diabetes 53: 1038-1045, 2004.
    • (2004) Diabetes , vol.53 , pp. 1038-1045
    • Wendt, A.1    Birnir, B.2    Buschard, K.3    Gromada, J.4    Salehi, A.5    Sewing, S.6    Rorsman, P.7    Braun, M.8


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