R-spondin-1 is a novel β-cell growth factor and insulin secretagogue

Journal of Biological Chemistry

Volumn 285, Issue 28, 2010, Pages 21292-21302

  Wong, Victor S C ^a   Yeung, Andrea ^a   Schultz, William ^a   Brubaker, Patricia L ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CELL LINES; CYTOKINES; GROWTH FACTOR; INSULIN SECRETION; MIN6 CELLS; MRNA EXPRESSION; PI3-KINASE; PRE-TREATMENT; SIGNALING PATHWAYS; STIMULATED CELLS; TARGET GENES; TIME-DEPENDENT; TRANSCRIPT LEVEL; TYPE-2 DIABETES;

BIOACTIVITY; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; GENE EXPRESSION; GLUCOSE; GROWTH KINETICS; INSULIN; PEPTIDES; SIGNALING; TARGETS; THERMAL CONDUCTIVITY;

CELL GROWTH;

BETA CATENIN; BROXURIDINE; EXENDIN 4; GAMMA INTERFERON; GLUCOSE; GROWTH FACTOR; INSULIN; INTERLEUKIN 1BETA; MESSENGER RNA; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; ROOF PLATE SPECIFIC SPONDIN 1; THYMIDINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL GROWTH; CELL LINE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; GENE TARGETING; INSULIN RELEASE; INSULINOMA; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MICE; MODELS, BIOLOGICAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; THROMBOSPONDINS; WNT PROTEINS;

MURINAE;

EID: 77954366964     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.129874     Document Type: Article

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