Myocardial expression, signaling, and function of GPR22: A protective role for an orphan G protein-coupled receptor

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 2, 2008, Pages

  Adams, John W ^a   Wang, Jianming ^b   Davis, James R ^a   Liaw, Chen ^a   Gaidarov, Ibragim ^a   Gatlin, Joel ^a   Dalton, Nancy D ^b   Gu, Yusu ^b   Ross Jr , John ^b   Behan, Dominic ^a   Chien, Ken ^c   Connolly, Daniel ^a  

^a ARENA PHARMACEUTICALS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Heart failure; Hypertrophy; Orphan receptor

Indexed keywords

ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; PROTEIN GRP22; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; GPR22 PROTEIN, HUMAN; GPR22 PROTEIN, MOUSE; GPR22 PROTEIN, RAT;

ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CORONARY ARTERY; GENE EXPRESSION; GENETIC TRANSFECTION; HEART AFTERLOAD; HEART FUNCTION; HEART MUSCLE CELL; HEART STRESS; HEMODYNAMIC STRESS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; ANIMAL; BRAIN; C57BL MOUSE; CARDIOMEGALY; CELL STRAIN COS1; CERCOPITHECUS; CORONARY BLOOD VESSEL; DISEASE MODEL; GENETICS; HEART CONTRACTION; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; MALE; METABOLISM; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADENYLATE CYCLASE; ANIMALS; BRAIN; CARDIOMEGALY; CERCOPITHECUS AETHIOPS; CORONARY VESSELS; COS CELLS; DISEASE MODELS, ANIMAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HEART FAILURE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION; VENTRICULAR FUNCTION, LEFT;

EID: 52449102485     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00368.2008     Document Type: Article

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