Nicotinic acid inhibits glucose-stimulated insulin secretion via the G protein-coupled receptor PUMA-G in murine islet β cells

Pancreas

Volumn 40, Issue 4, 2011, Pages 615-621

  Li, Hong Ming ^a   Zhang, Mei ^a   Xu, Sheng Tao ^a   Li, Di Zheng ^a   Zhu, Lin Yun ^a   Peng, Si Wu ^a   Chen, Guo Qiang ^a,b   Martin, Pamela M ^c   Ganapathy, Vadivel ^c   Wei, Chi Ju ^a  

^a SHANTOU UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

cAMP; diabetes; insulin secretion; Nicotinic acid; PUMA G

Indexed keywords

CALCIUM; CYCLIC AMP; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; GAMMA INTERFERON; GLUCOSE; INSULIN; NICOTINIC ACID; PERTUSSIS TOXIN; PUMA G PROTEIN; PUMA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL LEVEL; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE; IN SITU HYBRIDIZATION; INSULIN RELEASE; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CALCIUM; CYCLIC AMP; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE; IN SITU HYBRIDIZATION; INSULIN; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; ISLETS OF LANGERHANS; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; NIACIN; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VASODILATOR AGENTS;

EID: 79955061630     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e31820b4b23     Document Type: Article

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