Delta cell secretory responses to insulin secretagogues are not mediated indirectly by insulin

Diabetologia

Volumn 55, Issue 7, 2012, Pages 1995-2004

  Hauge Evans, A C ^a   Anderson, R L ^a   Persaud, S J ^a   Jones, P M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Delta cell; Insulin; Intra islet communication; Islets; Muscarinic M2 receptors; Paracrine; Somatostatin; TGP52

Indexed keywords

GLUCOSE; INSULIN; INSULIN DERIVATIVE; INSULIN RECEPTOR; INSULIN SECRETAGOGUE; MESSENGER RNA; METHOCTRAMINE; MUSCARINIC RECEPTOR; PERTUSSIS TOXIN; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOSTATIN; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LINE; CONTROLLED STUDY; GENE EXPRESSION; HORMONE RELEASE; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET DELTA CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; CELL LINE; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED ICR; RECEPTOR, INSULIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SOMATOSTATIN-SECRETING CELLS;

EID: 84866376327     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2546-9     Document Type: Article

References (57)

1. Bosco D, Orci L, Meda P (1989) Homologous but not heterolo-gous contact increases the insulin secretion of individual pancreatic B cells. Exp Cell Res 184:72-80
2. Halban PA, Wollheim CB, Blondel B, Meda P, Niesor EN, Mintz DH (1982) The possible importance of contact between pancreatic islet cells for the control of insulin release. Endocrinology 111:86-94
3. Hauge-Evans AC, Squires PE, Persaud SJ, Jones PM (1999) Pancreatic beta-cell-to-beta-cell interactions are required for integrated responses to nutrient stimuli: enhanced Ca2+ and insulin secretory responses of MIN6 pseudoislets. Diabetes 48:1402-1408
4. Hopcroft DW, Mason DR, Scott RS (1985) Insulin secretion from perifused rat pancreatic pseudoislets. In Vitro Cell Dev Biol 21:421-427
5. Luther MJ, Hauge-Evans A, Souza KL et al (2006) MIN6 beta-cell-beta-cell interactions influence insulin secretory responses to nutrients and non-nutrients. Biochem Biophys Res Commun 343:99-104
6. Brereton H, Carvell MJ, Persaud SJ, Jones PM (2007) Islet alpha-cells do not influence insulin secretion from beta-cells through cell-cell contact. Endocrine 31:61-65
7. Franklin I, Gromada J, Gjinovci A, Theander S, Wollheim CB (2005) Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release. Diabetes 54:1808-1815
8. Ishihara H, Maechler P, Gjinovci A, Herrera PL, Wollheim CB (2003) Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells. Nat Cell Biol 5:330-335
9. Ravier MA, Rutter GA (2005) Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells. Diabetes 54:1789-1797
10. Walker JN, Ramracheya R, Zhang Q, Johnson PR, Braun M, Rorsman P (2011) Regulation of glucagon secretion by glucose: paracrine, intrinsic or both? Diabetes Obes Metab 13(Suppl 1):95-105
11. Hauge-Evans AC, King AJ, Carmignac D et al (2009) Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function. Diabetes 58:403-411
12. Vieira E, Salehi A, Gylfe E (2007) Glucose inhibits glucagon secretion by a direct effect on mouse pancreatic alpha cells. Dia-betologia 50:370-379
13. Cejvan K, Coy DH, Holst JJ, Cerasi E, Efendic S (2002) Gliclazide directly inhibits arginine-induced glucagon release. Diabetes 51(Suppl 3):S381-S384
14. Sako Y, Wasada T, Umeda F, Ibayashi H (1986) Effect of gliben-clamide on pancreatic hormone release from isolated perifused islets of normal and cysteamine-treated rats. Metabolism 35:944-949
15. Guenifi A, Ahren B, Abdel-Halim SM (2001) Differential effects of glucagon-like peptide-1 (7-36) amide versus cholecystokinin on arginine-induced islet hormone release in vivo and in vitro. Pancreas 22:58-64
16. Silvestre RA, Rodriguez-Gallardo J, Egido EM, Marco J (2003) Interrelationship among insulin, glucagon and somatostatin secretory responses to exendin-4 in the perfused rat pancreas. Eur J Pharmacol 469:195-200
17. D'Alessio DA, Fujimoto WY, Ensinck JW (1989) Effects of glucagon-like peptide I-(7-36) on release of insulin, glucagon, and somatostatin by rat pancreatic islet cell monolayer cultures. Diabetes 38:1534-1538
18. Fehmann HC, Hering BJ, Wolf MJ et al (1995) The effects of glucagon-like peptide-I (GLP-I) on hormone secretion from isolated human pancreatic islets. Pancreas 11:196-200
19. Gros L, Thorens B, Bataille D, Kervran A (1993) Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line. Endocrinology 133:631-638
20. Heller RS, Aponte GW (1995) Intra-islet regulation of hormone secretion by glucagon-like peptide-1-(7-36) amide. Am J Physiol 269:G852-G860
21. Muller D, Huang GC, Amiel S, Jones PM, Persaud SJ (2007) Gene expression heterogeneity in human islet endocrine cells in vitro: the insulin signalling cascade. Diabetologia 50:1239-1242
22. Murakami K, Taniguchi H, Tamagawa M, Ejiri K, Baba S (1982) Modulation of somatostatin release by endogenous glucagon and insulin: physiological relationship between A, B and D cells in rat pancreatic islets. Endocrinol Jpn 29:503-508
23. Patton GS, Ipp E, Dobbs RE, Orci L, Vale W, Unger RH (1977) Pancreatic immunoreactive somatostatin release. Proc Natl Acad Sci USA 74:2140-2143
24. Stagner J, Samols E, Polonsky K, Pugh W (1986) Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas. J Clin Invest 78:1193-1198
25. Brunicardi FC, Kleinman R, Moldovan S et al (2001) Immuno-neutralization of somatostatin, insulin, and glucagon causes alterations in islet cell secretion in the isolated perfused human pancreas. Pancreas 23:302-308
26. Trimble ER, Gerber PP, Renold AE (1981) Abnormalities of pancreatic somatostatin secretion corrected by in vivo insulin treatment of streptozotocin-diabetic rats. Diabetes 30:865-867
27. Gey GO, Gey MK (2008) Maintenance of human normal cells in continuous culture, preliminary report: cultivation of mesoblastic tumours and normal cells and notes on methods of cultivation. Am J Cancer 27:45-76
28. Bradford MM (1976) A rapid and sensitive method for the quan-titation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
29. Hauge-Evans AC, Squires PE, Belin VD et al (2002) Role of adenine nucleotides in insulin secretion from MIN6 pseudoislets. Mol Cell Endocrinol 191:167-176
30. Gromada J, Holst JJ, Rorsman P (1998) Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1. Pflugers Arch 435:583-594
31. Lobner K, Steinbrenner H, Roberts GA et al (2002) Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life. Diabetes 51:2982-2988
32. Muller D, Jones PM, Persaud SJ (2006) Autocrine anti-apoptotic and proliferative effects of insulin in pancreatic beta-cells. FEBS Lett 580:6977-6980
33. Gilon P, Henquin JC (2001) Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function. Endocr Rev 22:565-604
34. Persaud SJ, Jones PM, Howell SL (1989) Effects of Bordetella pertussis toxin on catecholamine inhibition of insulin release from intact and electrically permeabilized rat islets. Biochem J 258:669-675
35. Cejvan K, Coy DH, Efendic S (2003) Intra-islet somatostatin regulates glucagon release via type 2 somatostatin receptors in rats. Diabetes 52:1176-1181
36. Utsumi M, Makimura H, Ishihara K, Morita S, Baba S (1979) Determination of immunoreactive somatostatin in rat plasma and responses to arginine, glucose and glucagon infusion. Diabetologia 17:319-323
37. Hellman B (2009) Pulsatility of insulin release-a clinically important phenomenon. Ups J Med Sci 114:193-205
38. Hoy M, Olsen HL, Bokvist K, Petersen JS, Gromada J (2003) The imidazoline NNC77-0020 affects glucose-dependent insulin, glu-cagon and somatostatin secretion in mouse pancreatic islets. Nau-nyn Schmiedebergs Arch Pharmacol 368:284-293
39. Obermuller S, Calegari F, King A et al (2010) Defective secretion of islet hormones in chromogranin-B deficient mice. PLoS One 5:e8936
40. Cabrera O, Berman DM, Kenyon NS, Ricordi C, Berggren PO, Caicedo A (2006) The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci USA 103:2334-2339
41. Schaffer L, Brand CL, Hansen BF et al (2008) A novel high-affinity peptide antagonist to the insulin receptor. Biochem Bio-phys Res Commun 376:380-383
42. Persaud SJ, Asare-Anane H, Jones PM (2002) Insulin receptor activation inhibits insulin secretion from human islets of Langer-hans. FEBS Lett 510:225-228
43. Persaud SJ (1999) Pancreatic beta-cell lines: their roles in beta-cell research and diabetes therapy. Adv Mol Cell Biol 29:21-46
44. Gopel SO, Kanno T, Barg S, Rorsman P (2000) Patch-clamp characterisation of somatostatin-secreting-cells in intact mouse pancreatic islets. J Physiol 528:497-507
45. Quesada I, Todorova MG, Soria B (2006) Different metabolic responses in alpha-, beta-, and delta-cells of the islet of Langerhans monitored by redox confocal microscopy. Biophys J 90:2641-2650
46. Berts A, Ball A, Dryselius G, Gylfe E, Hellman B (1996) Glucose stimulation of somatostatin-producing islet cells involves oscillatory Ca2+ signaling. Endocrinology 137:693-697
47. Hermansen K, Christensen SE, Orskov H (1979) Characterization of somatostatin release from the pancreas: the role of potassium. Scand J Clin Lab Invest 39:717-722
48. Hermansen K, Christensen SE, Orskov H (1979) Characterisation of somatostatin release from the pancreas: the role of calcium and acetylcholine. Diabetologia 16:261-266
49. Zhang Q, Bengtsson M, Partridge C et al (2007) R-type Ca (2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion. Nat Cell Biol 9:453-460
50. Heller RS, Kieffer TJ, Habener JF (1997) Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas. Diabetes 46:785-791
51. Tornehave D, Kristensen P, Romer J, Knudsen LB, Heller RS (2008) Expression of the GLP-1 receptor in mouse, rat, and human pancreas. J Histochem Cytochem 56:841-851
52. Moens K, Heimberg H, Flamez D et al (1996) Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes 45:257-261
53. Kieffer TJ, Heller RS, Unson CG, Weir GC, Habener JF (1996) Distribution of glucagon receptors on hormone-specific endocrine cells of rat pancreatic islets. Endocrinology 137:5119-5125
54. Itoh M, Gerich JE (1982) Adrenergic modulation of pancreatic somatostatin, insulin, and glucagon secretion: evidence for differential sensitivity of islet A, B, and D cells. Metabolism 31:715-720
55. Samols E, Weir GC (1979) Adrenergic modulation of pancreatic A, B, and D cells alpha-adrenergic suppression and beta-adrenergic stimulation of somatostatin secretion, alpha-adrenergic stimulation of glucagon secretion in the perfused dog pancreas. J Clin Invest 63:230-238
56. Gagerman E, Idahl LA, Meissner HP, Taljedal IB (1978) Insulin release, cGMP, cAMP, and membrane potential in acetylcholine-stimulated islets. Am J Physiol 235:E493-E500
57. Dunlop ME, Larkins RG (1986) Muscarinic-agonist and guanine nucleotide activation of polyphosphoinositide phosphodiesterase in isolated islet-cell membranes. Biochem J 240:731-737