Molecular pharmacological phenotyping of EBI2: An orphan seven-transmembrane receptor with constitutive activity

Journal of Biological Chemistry

Volumn 281, Issue 19, 2006, Pages 13199-13208

  Rosenkilde, Mette M ^a   Benned Jensen, Tau ^a   Andersen, Helene ^c   Holst, Peter J ^b   Kledal, Thomas N ^c   Lüttichau, Hans R ^a,d   Larsen, Jørgen K ^d   Christensen, Jan P ^b   Schwartz, Thue W ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Mental Health Services CPH   (Denmark)

^d FINSEN LABORATORY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CHROMOSOMES; GENES; GENETIC ENGINEERING; HISTOLOGY; IMMUNOLOGY; TISSUE; VIRUSES;

CONFOCAL MICROSCOPY; IMMUNOHISTOCHEMISTRY; LUNG TISSUE; MONONUCLEAR CELLS;

CELL MEMBRANES;

CYCLIC AMP; FORSKOLIN; GREEN FLUORESCENT PROTEIN; INOSITOL PHOSPHATE; PROTEIN BILF1; PROTEIN EPSTEIN BARR VIRUS INDUCED RECEPTOR 2; RHODOPSIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HUMANS; KILLER CELLS, NATURAL; LYMPHOCYTES; MONOCYTES; PROTEIN ISOFORMS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

HUMAN HERPESVIRUS 4;

EID: 33744948051     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M602245200     Document Type: Article

References (53)

1. Schwartz, T. W., and Holst, B. (2003) in Textbook of Receptor Pharmacology (Foreman, J. C., and Johansen, T., eds) pp. 65-85, CRC Press, Boca Raton, FL
2. Birkenbach, M., Josefsen, K., Yalamanchili, R., Lenoir, G., and Kieff, E. (1993) J. Virol. 67, 2209-2220
3. Yoshida, R., Imai, T., Hieshima, K., Kusuda, J., Baba, M., Kitaura, M., Nishimura, M., Kakizaki, M., Nomiyama, H., and Yoshie, O. (1997) J. Biol. Chem. 272, 13803-13809
4. Cahir-McFarland, E. D., Carter, K., Rosenwald, A., Giltnane, J. M., Henrickson, S. E., Staudt, L. M., and Kieff, E. (2004) J. Virol. 78, 4108-4119
5. Melchjorsen, J., Pedersen, F. S., Mogensen, S. C., and Paludan, S. R. (2002) J. Virol. 76, 2780-2788
6. Melchjorsen, J., Sorensen, L. N., and Paludan, S. R. (2003) J. Leukoc. Biol. 74, 331-343
7. Rosenkilde, M. M., and Kledal, T. N. (2006) Curr. Drug Targets 7, 103-118
8. Murphy, P. M. (2001) Nat. Immunol. 2, 116-122
9. Arvanitakis, L., Geras-Raaka, E., Varma, A., Gershengorn, M. C., and Cesarman, E. (1997) Nature 385, 347-350
10. Bais, C., Santomasso, B., Coso, O., Arvanitakis, L., Raaka, E. G., Gutkind, J. S., Asch, A. S., Cesarman, E., Gershengorn, M. C., Mesri, E. A., and Gerhengorn, M. C. (1998) Nature 391, 86-89
11. Rosenkilde, M. M., Kledal, T. N., Brauner-Osborne, H., and Schwartz, T. W. (1999) J. Biol. Chem. 274, 956-961
12. Goltz, M., Ericsson, T., Patience, C., Huang, C. A., Noack, S., Sachs, D. H., and Ehlers, B. (2002) Virology 294, 383-393
13. Paulsen, S. J., Rosenkilde, M. M., Eugen-Olsen, J., and Kledal, T. N. (2005) J. Virol. 79, 536-546
14. Beisser, P. S., Verzijl, D., Gruijthuijsen, Y. K., Beuken, E., Smit, M. J., Leurs, R., Bruggeman, C. A., and Vink, C. (2005) J. Virol. 79, 441-449
15. Farzan, M., Choe, H., Martin, K., Marcon, L., Hofmann, W., Karlsson, G., Sun, Y., Barrett, P., Marchand, N., Sullivan, N., Gerard, N., Gerard, C., and Sodroski, J. (1997) J. Exp. Med. 186, 405-411
16. Johansen, T. E., Schøller, M. S., Tolstoy, S., and Schwartz, T. W. (1990) FEBS Lett. 267, 289-294
17. Sabroe, I., Conroy, D. M., Gerard, N. P., Li, Y., Collins, P. D., Post, T. W., Jose, P. J., Williams, T. J., Gerard, C. J., and Ponath, P. D. (1998) J. Immunol. 161, 6139-6147
18. Kostenis, E. (2001) Trends Pharmacol. Sci. 22, 560-564
19. Berridge, M. J., Dawson, M. C., Downes, C. P., Heslop, J. P., and Irvin, R. F. (1983) Biochem. J. 212, 473-482
20. Lapinsh, M., Gutcaits, A., Prusis, P., Post, C., Lundstedt, T., and Wikberg, J. E. (2002) Protein Sci. 11, 795-805
21. Vassilatis, D. K., Hohmann, J. G., Zeng, H., Li, F., Ranchalis, J. E., Mortrud, M. T., Brown, A., Rodriguez, S. S., Weller, J. R., Wright, A. C., Bergmann, J. E., and Gaitanaris, G. A. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 4903- 4908
22. Joost, P., and Methner, A. (2002) Genome Biology http://genomebiology. com/2002/3/11/research/0063
23. Rosenkilde, M. M., and Schwartz, T. W. (2004) in Handbook of Cell Signaling (Bradshaw, R. A., and Dennis, E. A., eds) pp. 779 -785, Elsevier, New York
24. Murphy, P. M., Baggiolini, M., Charo, I. F., Hebert, C. A., Horuk, R., Matsushima, K., Miller, L. H., Oppenheim, J. J., and Power, C. A. (2000) Pharmacol. Rev. 52, 145-176
25. Conklin, B. R., Herzmark, P., Ishida, S., Voyno-Yasenetskaya, T. A., Sun, Y., Farfel, Z., and Bourne, H. R. (1996) Mol. Pharmacol. 50, 885-890
26. Hill, S. J., Baker, J. G., and Rees, S. (2001) Curr. Opin. Pharmacol. 1, 526-532
27. Matthews, R. P., Guthrie, C. R., Wailes, L. M., Zhao, X., Means, A. R., and McKnight, G. S. (1994) Mol. Cell Biol. 14, 6107-6116
28. Cannon, M., Philpott, N. J., and Cesarman, E. (2003) J. Virol. 77, 57-67
29. Couty, J. P., Geras-Raaka, E., Weksler, B. B., and Gershengorn, M. C. (2001) J. Biol. Chem. 276, 33805-33811
30. Montaner, S., Sodhi, A., Pece, S., Mesri, E. A., and Gutkind, J. S. (2001) Cancer Res. 61, 2641-2648
31. Shepard, L. W., Yang, M., Xie, P., Browning, D. D., Voyno-Yasenetskaya, T., Kozasa, T., and Ye, R. D. (2001) J. Biol. Chem. 276, 45979-45987
32. Liu, C., Sandford, G., Fei, G., and Nicholas, J. (2004) J. Virol. 78, 2460-2471
33. Rosenkilde, M. M., McLean, K. A., Holst, P. J., and Schwartz, T. W. (2004) J. Biol. Chem. 279, 32524-32533
34. Holst, B., Holliday, N. D., Bach, A., Elling, C. E., Cox, H. M., and Schwartz, T. W. (2004) J. Biol. Chem. 279, 53806-53817
35. Ponimaskin, E. G., Profirovic, J., Vaiskunaite, R., Richter, D. W., and Voyno-Yasenetskaya, T. A. (2002) J. Biol. Chem. 277, 20812-20819
36. Gruijthuijsen, Y. K., Casarosa, P., Kaptein, S. J., Broers, J. L., Leurs, R., Bruggeman, C. A., Smit, M. J., and Vink, C. (2002) J. Virol. 76, 1328-1338
37. Mao, J., Yuan, H., Xie, W., Simon, M. I., and Wu, D. (1998) J. Biol. Chem. 273, 27118-27123
38. Birkenbach, M., Liebowitz, D., Wang, F., Sample, J., and Kieff, E. (1989) J. Virol. 63, 4079-4084
39. Couty, J. P., and Gershengorn, M. C. (2005) Trends Pharmacol. Sci. 26, 405-411
40. Rosenkilde, M. M., Kledal, T. N., and Schwartz, T. W. (2005) Mol. Pharmacol. 68, 11-19
41. Holst, B., Cygankiewicz, A., Jensen, T. H., Ankersen, M., and Schwartz, T. W. (2003) Mol. Endocrinol. 17, 2201-2210
42. Rosenkilde, M. M. (2005) Neuropharmacology 48, 1-13
43. Uhlenbrock, K., Gassenhuber, H., and Kostenis, E. (2002) Cell Signal. 14, 941-953
44. Parma, J., Van-Sande, J., Swillens, S., Tonacchera, M., Dumont, J., and Vassart, G. (1995) Mol. Endocrinol. 9, 725-733
45. Robbins, L. S., Nadeau, J. H., Johnson, K. R., Kelly, M. A., Roselli-Rehfuss, L., Baack, E., Mountjoy, K. G., and Cone, R. D. (1993) Cell 72, 1-20
46. Neote, K., DiGregorio, D., Mak, J. Y., Horuk, R., and Schall, T. J. (1993) Cell 72, 415-425
47. Ahuja, S. K., and Murphy, P. M. (1993) J. Biol. Chem. 268, 20691-20694
48. Lindow, M., Luttichau, H. R., and Schwartz, T. W. (2003) Trends Pharmacol. Sci. 24, 126-130
49. Moorman, N. J., Virgin, H. W., and Speck, S. H. (2003) Virology 307, 179-190
50. Nakayama, T., Fujisawa, R., Izawa, D., Hieshima, K., Takada, K., and Yoshie, O. (2002) J. Virol. 76, 3072-3077
51. Seifert, R., and Wenzel-Seifert, K. (2001) Receptors Channels 7, 357-369
52. Holst, B., and Schwartz, T. W. (2004) Trends Pharmacol. Sci. 25, 113-117
53. Nijenhuis, W. A., Oosterom, J., and Adan, R. A. (2001) Mol. Endocrinol. 15, 164-171