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Volumn 43, Issue 8, 2000, Pages 1012-1019

Glucagon receptors on human islet cells contribute to glucose competence of insulin release

Author keywords

Beta cells; Cyclic AMP; Diabetes; GIP receptors; GLP 1 receptors; Glucagon receptors; Glucose competence; Insulin

Indexed keywords

CYCLIC AMP; GLUCAGON; GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE RECEPTOR; GLUCAGON RECEPTOR; GLUCOSE; GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR; HORMONE DERIVATIVE; HORMONE RECEPTOR; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; INCRETIN RECEPTOR; INSULIN; UNCLASSIFIED DRUG;

EID: 0033847126     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051484     Document Type: Article
Times cited : (177)

References (48)
  • 3
    • 13344293675 scopus 로고    scopus 로고
    • Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat dpancreatic islet cells
    • (1996) Diabetes , vol.45 , pp. 257-261
    • Moens, K.1    Heimberg, H.2    Flamez, D.3
  • 6
    • 0028933090 scopus 로고
    • Regulation of glucagon and glucagon-like peptide-1 receptor messenger ribo-nucleic acid expression in cultured rat pancreatic islets by glucose, cyclic adenosine 3',5'-monophosphate, and glucocorticoids
    • (1995) Endocrinology , vol.136 , pp. 1572-1578
    • Abrahamsen, N.1    Nishimura, E.2
  • 17
    • 0030467497 scopus 로고    scopus 로고
    • Prolonged exposure of human beta cells to elevated glucose levels results insustained cellular activation leading to a loss of glucose regulation
    • (1996) J Clin Invest , vol.98 , pp. 2805-2812
    • Ling, Z.1    Pipeleers, D.G.2
  • 24
    • 0032960834 scopus 로고
    • Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: Studies with the antagonist exendin 9-39
    • (1994) Diabetes , vol.48 , pp. 86-93
    • Edwards, C.M.1    Todd, J.F.2    Mahmoudi, M.3
  • 26
    • 0029077296 scopus 로고
    • Cloning, functional expression and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor
    • (1995) Diabetes , vol.44 , pp. 1202-1208
    • Gremlich, S.1    Porret, A.2    Hani, E.H.3
  • 33
    • 0025597875 scopus 로고
    • Elusive proximal signals of beta-cells for insulin secretion
    • (1990) Diabetes , vol.39 , pp. 1461-1466
    • MacDonald, M.J.1
  • 40
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin (9-39)amide an antagonist at the glucagon-like peptide 1 (7-36)amide receptor of insulin-secreting β-cells
    • (1993) J Biol Chem , vol.268 , pp. 19650-19655
    • Goke, R.1    Fehmann, H.C.2    Linn, T.3
  • 44
    • 0029948151 scopus 로고    scopus 로고
    • The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon
    • (1996) Diabetes , vol.45 , pp. 725-730
    • Hansen, L.H.1    Abrahamsen, N.2    Hager, J.3
  • 48
    • 0033609824 scopus 로고    scopus 로고
    • Characterization of the carboxyl-terminal domain of the ratglucose-dependent insulinotropic polypeptide (GIP) receptor. A role for serines 426 and 427 in regulating the rate of internalization
    • (1999) J Biol Chem , vol.274 , pp. 24593-24601
    • Wheeler, M.B.1    Gelling, R.W.2    Hinke, S.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.