-
1
-
-
78650641554
-
Nanocarriers for pulmonary administration of peptides and therapeutic proteins
-
Andrade F., Videira M., Ferreira D., Sarmento B. Nanocarriers for pulmonary administration of peptides and therapeutic proteins. Nanomedicine 2011, 6:123-141.
-
(2011)
Nanomedicine
, vol.6
, pp. 123-141
-
-
Andrade, F.1
Videira, M.2
Ferreira, D.3
Sarmento, B.4
-
2
-
-
0035888373
-
Insulin therapies-past, present and future
-
Pillai O., Panchagnula R. Insulin therapies-past, present and future. Drug Discov. Today 2001, 6:1056-1061.
-
(2001)
Drug Discov. Today
, vol.6
, pp. 1056-1061
-
-
Pillai, O.1
Panchagnula, R.2
-
3
-
-
80054061227
-
A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery
-
Chen M.C., Sonaje K., Chen K.J., Sung H.W. A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery. Biomaterials 2011, 32:9826-9838.
-
(2011)
Biomaterials
, vol.32
, pp. 9826-9838
-
-
Chen, M.C.1
Sonaje, K.2
Chen, K.J.3
Sung, H.W.4
-
4
-
-
0022468493
-
A new approach to the oral administration of insulin and other peptide drugs
-
Saffran M., Kumar G.S., Savariar C., Burnham J.C., Williams F., Neckers D.C. A new approach to the oral administration of insulin and other peptide drugs. Science 1986, 233:1081-1084.
-
(1986)
Science
, vol.233
, pp. 1081-1084
-
-
Saffran, M.1
Kumar, G.S.2
Savariar, C.3
Burnham, J.C.4
Williams, F.5
Neckers, D.C.6
-
5
-
-
0030460690
-
Oral controlled release technology for peptides: status and future prospects
-
Fix J.A. Oral controlled release technology for peptides: status and future prospects. Pharm. Res. 1996, 13:1760-1764.
-
(1996)
Pharm. Res.
, vol.13
, pp. 1760-1764
-
-
Fix, J.A.1
-
6
-
-
0035813752
-
Oral drug absorption enhancement by chitosan and its derivatives
-
Thanou M., Verhoef J., Junginger H. Oral drug absorption enhancement by chitosan and its derivatives. Adv. Drug Deliv. Rev. 2001, 52:117-126.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.52
, pp. 117-126
-
-
Thanou, M.1
Verhoef, J.2
Junginger, H.3
-
7
-
-
80052297372
-
Chitosan: its applications in drug-eluting devices
-
Chen M.C., Mi F.L., Liao Z.X., Sung H.W. Chitosan: its applications in drug-eluting devices. Adv. Polym. Sci. 2011, 243:185-230.
-
(2011)
Adv. Polym. Sci.
, vol.243
, pp. 185-230
-
-
Chen, M.C.1
Mi, F.L.2
Liao, Z.X.3
Sung, H.W.4
-
8
-
-
33747846583
-
Chitin and chitosan: properties and applications
-
Rinaudo M. Chitin and chitosan: properties and applications. Prog. Polym. Sci. 2006, 31:603-632.
-
(2006)
Prog. Polym. Sci.
, vol.31
, pp. 603-632
-
-
Rinaudo, M.1
-
9
-
-
85007774154
-
Increasing effect of a chitosan and ascorbic acid mixture on fecal dietary fat excretion
-
Kanauchi O., Deuchi K., Imasato Y., Kobayashi E. Increasing effect of a chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci. Biotechnol. Biochem. 1994, 58:1617-1620.
-
(1994)
Biosci. Biotechnol. Biochem.
, vol.58
, pp. 1617-1620
-
-
Kanauchi, O.1
Deuchi, K.2
Imasato, Y.3
Kobayashi, E.4
-
10
-
-
0000129504
-
Hypocholesterolemic effect of chitosan in adult males
-
Maezaki Y., Tsuji K., Nakagawa Y., Kawai Y., Akimoto M., Tsugita T., Takekawa W., Terada A., Hara H., Mitsuoka T. Hypocholesterolemic effect of chitosan in adult males. Biosci. Biotechnol. Biochem. 1993, 57:1439-1444.
-
(1993)
Biosci. Biotechnol. Biochem.
, vol.57
, pp. 1439-1444
-
-
Maezaki, Y.1
Tsuji, K.2
Nakagawa, Y.3
Kawai, Y.4
Akimoto, M.5
Tsugita, T.6
Takekawa, W.7
Terada, A.8
Hara, H.9
Mitsuoka, T.10
-
12
-
-
0032958073
-
Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
-
Roy K., Mao H.Q., Huang S.K., Leong K.W. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat. Med. 1999, 5:387-391.
-
(1999)
Nat. Med.
, vol.5
, pp. 387-391
-
-
Roy, K.1
Mao, H.Q.2
Huang, S.K.3
Leong, K.W.4
-
13
-
-
78649905059
-
The impact of vehicles on the mucoadhesive properties of orally administrated nanoparticles: a case study with chitosan-4-thiobutylamidine conjugate
-
Sakloetsakun D., Perera G., Hombach J., Millotti G., Bernkop-Schnürch A. The impact of vehicles on the mucoadhesive properties of orally administrated nanoparticles: a case study with chitosan-4-thiobutylamidine conjugate. AAPS PharmSciTech 2010, 11:1185-1192.
-
(2010)
AAPS PharmSciTech
, vol.11
, pp. 1185-1192
-
-
Sakloetsakun, D.1
Perera, G.2
Hombach, J.3
Millotti, G.4
Bernkop-Schnürch, A.5
-
14
-
-
80052278049
-
Chitosan and its derivatives for drug delivery perspective
-
Sonia T., Sharma C. Chitosan and its derivatives for drug delivery perspective. Adv. Polym. Sci. 2011, 243:23-54.
-
(2011)
Adv. Polym. Sci.
, vol.243
, pp. 23-54
-
-
Sonia, T.1
Sharma, C.2
-
15
-
-
75149183537
-
Chitosan-based delivery systems for protein therapeutics and antigens
-
Amidi M., Mastrobattista E., Jiskoot W., Hennink W.E. Chitosan-based delivery systems for protein therapeutics and antigens. Adv. Drug Deliv. Rev. 2010, 62:59-82.
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 59-82
-
-
Amidi, M.1
Mastrobattista, E.2
Jiskoot, W.3
Hennink, W.E.4
-
16
-
-
80052966755
-
Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins
-
Sonaje K., Lin K.J., Tseng M.T., Wey S.P., Su F.Y., Chuang E.Y., Hsu C.W., Chen C.T., Sung H.W. Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins. Biomaterials 2011, 32:8712-8721.
-
(2011)
Biomaterials
, vol.32
, pp. 8712-8721
-
-
Sonaje, K.1
Lin, K.J.2
Tseng, M.T.3
Wey, S.P.4
Su, F.Y.5
Chuang, E.Y.6
Hsu, C.W.7
Chen, C.T.8
Sung, H.W.9
-
17
-
-
33947530087
-
Novel nanoparticles for oral insulin delivery via the paracellular pathway
-
Lin Y.H., Chen C.T., Liang H.F., Kulkarni A.R., Lee P.W., Chen C.H., Sung H.W. Novel nanoparticles for oral insulin delivery via the paracellular pathway. Nanotechnology 2007, 18:105102.
-
(2007)
Nanotechnology
, vol.18
, pp. 105102
-
-
Lin, Y.H.1
Chen, C.T.2
Liang, H.F.3
Kulkarni, A.R.4
Lee, P.W.5
Chen, C.H.6
Sung, H.W.7
-
18
-
-
70349784917
-
The characteristics, biodistribution and bioavailability of a chitosan-based nanoparticulate system for the oral delivery of heparin
-
Chen M.C., Wong H.S., Lin K.J., Chen H.L., Wey S.P., Sonaje K., Lin Y.H., Chu C.Y., Sung H.W. The characteristics, biodistribution and bioavailability of a chitosan-based nanoparticulate system for the oral delivery of heparin. Biomaterials 2009, 30:6629-6637.
-
(2009)
Biomaterials
, vol.30
, pp. 6629-6637
-
-
Chen, M.C.1
Wong, H.S.2
Lin, K.J.3
Chen, H.L.4
Wey, S.P.5
Sonaje, K.6
Lin, Y.H.7
Chu, C.Y.8
Sung, H.W.9
-
19
-
-
35549012407
-
Oral bioavailability of insulin contained in polysaccharide nanoparticles
-
Sarmento B., Ribeiro A., Veiga F., Ferreira D., Neufeld R. Oral bioavailability of insulin contained in polysaccharide nanoparticles. Biomacromolecules 2007, 8:3054-3060.
-
(2007)
Biomacromolecules
, vol.8
, pp. 3054-3060
-
-
Sarmento, B.1
Ribeiro, A.2
Veiga, F.3
Ferreira, D.4
Neufeld, R.5
-
20
-
-
79251593382
-
The glucose-lowering potential of exendin-4 orally delivered via a pH-sensitive nanoparticle vehicle and effects on subsequent insulin secretion in vivo
-
Nguyen H.N., Wey S.P., Juang J.H., Sonaje K., Ho Y.C., Chuang E.Y., Hsu C.W., Yen T.C., Lin K.J., Sung H.W. The glucose-lowering potential of exendin-4 orally delivered via a pH-sensitive nanoparticle vehicle and effects on subsequent insulin secretion in vivo. Biomaterials 2011, 32:2673-2682.
-
(2011)
Biomaterials
, vol.32
, pp. 2673-2682
-
-
Nguyen, H.N.1
Wey, S.P.2
Juang, J.H.3
Sonaje, K.4
Ho, Y.C.5
Chuang, E.Y.6
Hsu, C.W.7
Yen, T.C.8
Lin, K.J.9
Sung, H.W.10
-
21
-
-
33644922361
-
Efficacy and mechanism of action of chitosan nanocapsules for oral peptide delivery
-
Prego C., Fabre M., Torres D., Alonso M. Efficacy and mechanism of action of chitosan nanocapsules for oral peptide delivery. Pharm. Res. 2006, 23:549-556.
-
(2006)
Pharm. Res.
, vol.23
, pp. 549-556
-
-
Prego, C.1
Fabre, M.2
Torres, D.3
Alonso, M.4
-
22
-
-
33846799473
-
Mucoadhesion mechanism of chitosan and thiolated chitosan-poly (isobutyl cyanoacrylate) core-shell nanoparticles
-
Bravo-Osuna I., Vauthier C., Farabollini A., Palmieri G.F., Ponchel G. Mucoadhesion mechanism of chitosan and thiolated chitosan-poly (isobutyl cyanoacrylate) core-shell nanoparticles. Biomaterials 2007, 28:2233-2243.
-
(2007)
Biomaterials
, vol.28
, pp. 2233-2243
-
-
Bravo-Osuna, I.1
Vauthier, C.2
Farabollini, A.3
Palmieri, G.F.4
Ponchel, G.5
-
23
-
-
0344359721
-
Chitosan for enhanced intestinal permeability: prospects for derivatives soluble in neutral and basic environments
-
Kotze A.F., Luessen H.L., de Boer A.G., Verhoef J.C., Junginger H.E. Chitosan for enhanced intestinal permeability: prospects for derivatives soluble in neutral and basic environments. Eur. J. Pharm. Sci. 1999, 7:145-151.
-
(1999)
Eur. J. Pharm. Sci.
, vol.7
, pp. 145-151
-
-
Kotze, A.F.1
Luessen, H.L.2
de Boer, A.G.3
Verhoef, J.C.4
Junginger, H.E.5
-
24
-
-
50249129610
-
Permeation enhancer effect of chitosan and chitosan derivatives: comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells
-
Sadeghi A.M., Dorkoosh F.A., Avadi M.R., Weinhold M., Bayat A., Delie F., Gurny R., Larijani B., Rafiee-Tehrani M., Junginger H.E. Permeation enhancer effect of chitosan and chitosan derivatives: comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells. Eur. J. Pharm. Biopharm. 2008, 70:270-278.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, pp. 270-278
-
-
Sadeghi, A.M.1
Dorkoosh, F.A.2
Avadi, M.R.3
Weinhold, M.4
Bayat, A.5
Delie, F.6
Gurny, R.7
Larijani, B.8
Rafiee-Tehrani, M.9
Junginger, H.E.10
-
25
-
-
77950916224
-
Insulin-loaded nanoparticles based on N-trimethyl chitosan: in vitro (Caco-2 model) and ex vivo (excised rat jejunum, duodenum, and ileum) evaluation of penetration enhancement properties
-
Sandri G., Bonferoni M.C., Rossi S., Ferrari F., Boselli C., Caramella C. Insulin-loaded nanoparticles based on N-trimethyl chitosan: in vitro (Caco-2 model) and ex vivo (excised rat jejunum, duodenum, and ileum) evaluation of penetration enhancement properties. AAPS PharmSciTech 2010, 11:362-371.
-
(2010)
AAPS PharmSciTech
, vol.11
, pp. 362-371
-
-
Sandri, G.1
Bonferoni, M.C.2
Rossi, S.3
Ferrari, F.4
Boselli, C.5
Caramella, C.6
-
26
-
-
0034879035
-
Chitosan: some pharmaceutical and biological aspects-an update
-
Singla A., Chawla M. Chitosan: some pharmaceutical and biological aspects-an update. J. Pharm. Pharmacol. 2001, 53:1047-1067.
-
(2001)
J. Pharm. Pharmacol.
, vol.53
, pp. 1047-1067
-
-
Singla, A.1
Chawla, M.2
-
27
-
-
0037472115
-
Chitosan-based gastrointestinal delivery systems
-
Hejazi R., Amiji M. Chitosan-based gastrointestinal delivery systems. J. Control. Release 2003, 89:151-165.
-
(2003)
J. Control. Release
, vol.89
, pp. 151-165
-
-
Hejazi, R.1
Amiji, M.2
-
28
-
-
0033960143
-
Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers
-
Thanou M., Kotze A., Scharringhausen T., Lueßen H., De Boer A., Verhoef J., Junginger H. Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers. J. Control. Release 2000, 64:15-25.
-
(2000)
J. Control. Release
, vol.64
, pp. 15-25
-
-
Thanou, M.1
Kotze, A.2
Scharringhausen, T.3
Lueßen, H.4
De Boer, A.5
Verhoef, J.6
Junginger, H.7
-
29
-
-
0038460837
-
Thiolated polymers-thiomers: synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates
-
Bernkop-Schnürch A., Hornof M., Zoidl T. Thiolated polymers-thiomers: synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates. Int. J. Pharm. 2003, 260:229-237.
-
(2003)
Int. J. Pharm.
, vol.260
, pp. 229-237
-
-
Bernkop-Schnürch, A.1
Hornof, M.2
Zoidl, T.3
-
30
-
-
0347985635
-
Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: synthesis and in vitro evaluation
-
Roldo M., Hornof M., Caliceti P., Bernkop-Schnürch A. Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: synthesis and in vitro evaluation. Eur. J. Pharm. Biopharm. 2004, 57:115-121.
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.57
, pp. 115-121
-
-
Roldo, M.1
Hornof, M.2
Caliceti, P.3
Bernkop-Schnürch, A.4
-
31
-
-
0346735298
-
Thiolated chitosans: development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery system
-
Bernkop-Schnürch A., Guggi D., Pinter Y. Thiolated chitosans: development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery system. J. Control. Release 2004, 94:177-186.
-
(2004)
J. Control. Release
, vol.94
, pp. 177-186
-
-
Bernkop-Schnürch, A.1
Guggi, D.2
Pinter, Y.3
-
32
-
-
33646492929
-
Tight junction modulation and its relationship to drug delivery
-
Salama N.N., Eddington N.D., Fasano A. Tight junction modulation and its relationship to drug delivery. Adv. Drug Deliv. Rev. 2006, 58:15-28.
-
(2006)
Adv. Drug Deliv. Rev.
, vol.58
, pp. 15-28
-
-
Salama, N.N.1
Eddington, N.D.2
Fasano, A.3
-
34
-
-
0016358918
-
Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine I. Columnar cell
-
Cheng H., Leblond C.P. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine I. Columnar cell. Am. J. Anat. 1974, 141:461-479.
-
(1974)
Am. J. Anat.
, vol.141
, pp. 461-479
-
-
Cheng, H.1
Leblond, C.P.2
-
35
-
-
85013717278
-
-
4th edition, in: E.M. Wright, D.D.F. Loo, B.A. Hirayama, and E. Turk (eds.), Chapter 64. Sugar Absorption, edited by Johnson et al. Elsevier Inc., San Diego
-
L.R. Johnson, K.E. Barret, F.K. Gishan, J.L. Merchant, H.M. Said, J.D. Wood, Physiology of the gastrointestinal tract. 4th edition, in: E.M. Wright, D.D.F. Loo, B.A. Hirayama, and E. Turk (eds.), Chapter 64. Sugar Absorption, edited by Johnson et al. Elsevier Inc., San Diego, 2006, pp. 1653-1665.
-
(2006)
Physiology of the gastrointestinal tract
, pp. 1653-1665
-
-
Johnson, L.R.1
Barret, K.E.2
Gishan, F.K.3
Merchant, J.L.4
Said, H.M.5
Wood, J.D.6
-
36
-
-
0017686274
-
Glycoprotein synthesis, transport, and secretion by epithelial cells of human rectal mucosa: normal and cystic fibrosis
-
Neutra M., Grand R., Trier J. Glycoprotein synthesis, transport, and secretion by epithelial cells of human rectal mucosa: normal and cystic fibrosis. Lab. Invest. 1977, 36:535-546.
-
(1977)
Lab. Invest.
, vol.36
, pp. 535-546
-
-
Neutra, M.1
Grand, R.2
Trier, J.3
-
37
-
-
0013924545
-
Synthesis of the carbohydrate of mucus in the Golgi complex as shown by electron microscope radioautography of goblet cells from rats injected with glucose-H3
-
Neutra M., Leblond C. Synthesis of the carbohydrate of mucus in the Golgi complex as shown by electron microscope radioautography of goblet cells from rats injected with glucose-H3. J. Cell Biol. 1966, 30:119-136.
-
(1966)
J. Cell Biol.
, vol.30
, pp. 119-136
-
-
Neutra, M.1
Leblond, C.2
-
38
-
-
4544258068
-
NALT- versus Peyer's-patch-mediated mucosal immunity
-
Kiyono H., Fukuyama S. NALT- versus Peyer's-patch-mediated mucosal immunity. Nat. Rev. Immunol. 2004, 4:699-710.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 699-710
-
-
Kiyono, H.1
Fukuyama, S.2
-
39
-
-
33745370633
-
Intestinal absorptive transport of the hydrophilic cation ranitidine: a kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in Caco-2 cells
-
Bourdet D.L., Pollack G.M., Thakker D.R. Intestinal absorptive transport of the hydrophilic cation ranitidine: a kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in Caco-2 cells. Pharm. Res. 2006, 23:1178-1187.
-
(2006)
Pharm. Res.
, vol.23
, pp. 1178-1187
-
-
Bourdet, D.L.1
Pollack, G.M.2
Thakker, D.R.3
-
40
-
-
33846410236
-
Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery
-
Lin Y.H., Mi F.L., Chen C.T., Chang W.C., Peng S.F., Liang H.F., Sung H.W. Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery. Biomacromolecules 2007, 8:146-152.
-
(2007)
Biomacromolecules
, vol.8
, pp. 146-152
-
-
Lin, Y.H.1
Mi, F.L.2
Chen, C.T.3
Chang, W.C.4
Peng, S.F.5
Liang, H.F.6
Sung, H.W.7
-
41
-
-
0035722976
-
Effect of preparation conditions on properties and permeability of chitosansodium hexametaphosphate capsules
-
Angelova N., Hunkeler D. Effect of preparation conditions on properties and permeability of chitosansodium hexametaphosphate capsules. J. Biomater. Sci. Polym. Ed. 2001, 12:1317-1337.
-
(2001)
J. Biomater. Sci. Polym. Ed.
, vol.12
, pp. 1317-1337
-
-
Angelova, N.1
Hunkeler, D.2
-
42
-
-
0036692366
-
Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport
-
Behrens I., Pena A.I.V., Alonso M.J., Kissel T. Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport. Pharm. Res. 2002, 19:1185-1193.
-
(2002)
Pharm. Res.
, vol.19
, pp. 1185-1193
-
-
Behrens, I.1
Pena, A.I.V.2
Alonso, M.J.3
Kissel, T.4
-
43
-
-
73849149819
-
Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes
-
Kadiyala I., Loo Y., Roy K., Rice J., Leong K.W. Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes. Eur. J. Pharm. Sci. 2010, 39:103-109.
-
(2010)
Eur. J. Pharm. Sci.
, vol.39
, pp. 103-109
-
-
Kadiyala, I.1
Loo, Y.2
Roy, K.3
Rice, J.4
Leong, K.W.5
-
44
-
-
33751253462
-
Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach
-
Des Rieux A., Fievez V., Garinot M., Schneider Y.J., Préat V. Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach. J. Control. Release 2006, 116:1-27.
-
(2006)
J. Control. Release
, vol.116
, pp. 1-27
-
-
Des Rieux, A.1
Fievez, V.2
Garinot, M.3
Schneider, Y.J.4
Préat, V.5
-
45
-
-
21744458087
-
Nanoparticle uptake by the oral route: fulfilling its potential?
-
Florence A.T. Nanoparticle uptake by the oral route: fulfilling its potential?. Drug Discov. Today 2005, 2:75-81.
-
(2005)
Drug Discov. Today
, vol.2
, pp. 75-81
-
-
Florence, A.T.1
-
46
-
-
0030471901
-
Gastrointestinal uptake of biodegradable microparticles: effect of particle size
-
Desai M.P., Labhasetwar V., Amidon G.L., Levy R.J. Gastrointestinal uptake of biodegradable microparticles: effect of particle size. Pharm. Res. 1996, 13:1838-1845.
-
(1996)
Pharm. Res.
, vol.13
, pp. 1838-1845
-
-
Desai, M.P.1
Labhasetwar, V.2
Amidon, G.L.3
Levy, R.J.4
-
47
-
-
0030993565
-
The oral absorption of micro-and nanoparticulates: neither exceptional nor unusual
-
Florence A.T. The oral absorption of micro-and nanoparticulates: neither exceptional nor unusual. Pharm. Res. 1997, 14:259-266.
-
(1997)
Pharm. Res.
, vol.14
, pp. 259-266
-
-
Florence, A.T.1
-
48
-
-
57049145802
-
Bioavailability of nanoparticles in nutrient and nutraceutical delivery
-
Acosta E. Bioavailability of nanoparticles in nutrient and nutraceutical delivery. Colloid Interface Sci. 2009, 14:3-15.
-
(2009)
Colloid Interface Sci.
, vol.14
, pp. 3-15
-
-
Acosta, E.1
-
49
-
-
0035937594
-
Mucoadhesive nanoparticulate systems for peptide drug delivery
-
Takeuchi H., Yamamoto H., Kawashima Y. Mucoadhesive nanoparticulate systems for peptide drug delivery. Adv. Drug Deliv. Rev. 2001, 47:39-54.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.47
, pp. 39-54
-
-
Takeuchi, H.1
Yamamoto, H.2
Kawashima, Y.3
-
50
-
-
68549122512
-
Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery
-
Yin L., Ding J., He C., Cui L., Tang C., Yin C. Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery. Biomaterials 2009, 30:5691-5700.
-
(2009)
Biomaterials
, vol.30
, pp. 5691-5700
-
-
Yin, L.1
Ding, J.2
He, C.3
Cui, L.4
Tang, C.5
Yin, C.6
-
51
-
-
0032971987
-
Evaluation of the clearance characteristics of bioadhesive systems in humans
-
Soane R., Frier M., Perkins A., Jones N., Davis S., Illum L. Evaluation of the clearance characteristics of bioadhesive systems in humans. Int. J. Pharm. 1999, 178:55-65.
-
(1999)
Int. J. Pharm.
, vol.178
, pp. 55-65
-
-
Soane, R.1
Frier, M.2
Perkins, A.3
Jones, N.4
Davis, S.5
Illum, L.6
-
52
-
-
84856599906
-
Chitosan enhances transcellular permeability in human and rat intestine epithelium
-
Magdalena Canali M., Pedrotti L., Balsinde J., Ibarra C., Correa S.G. Chitosan enhances transcellular permeability in human and rat intestine epithelium. Eur. J. Pharm. Biopharm. 2012, 80:418-425.
-
(2012)
Eur. J. Pharm. Biopharm.
, vol.80
, pp. 418-425
-
-
Magdalena Canali, M.1
Pedrotti, L.2
Balsinde, J.3
Ibarra, C.4
Correa, S.G.5
-
53
-
-
33748131292
-
Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination
-
Borges O., Cordeiro-da-Silva A., Romeijn S.G., Amidi M., De Sousa A., Borchard G., Junginger H.E. Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination. J. Control. Release 2006, 114:348-358.
-
(2006)
J. Control. Release
, vol.114
, pp. 348-358
-
-
Borges, O.1
Cordeiro-da-Silva, A.2
Romeijn, S.G.3
Amidi, M.4
De Sousa, A.5
Borchard, G.6
Junginger, H.E.7
-
54
-
-
79957529691
-
Facilitated nanoscale delivery of insulin across intestinal membrane models
-
Woitiski C.B., Sarmento B., Carvalho R.A., Neufeld R.J., Veiga F. Facilitated nanoscale delivery of insulin across intestinal membrane models. Int. J. Pharm. 2011, 412:123-131.
-
(2011)
Int. J. Pharm.
, vol.412
, pp. 123-131
-
-
Woitiski, C.B.1
Sarmento, B.2
Carvalho, R.A.3
Neufeld, R.J.4
Veiga, F.5
-
55
-
-
19444373410
-
θ Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability
-
Banan A., Zhang L., Shaikh M., Fields J., Choudhary S., Forsyth C., Farhadi A., Keshavarzian A. θ Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability. J. Pharmacol. Exp. Ther. 2005, 313:962-982.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.313
, pp. 962-982
-
-
Banan, A.1
Zhang, L.2
Shaikh, M.3
Fields, J.4
Choudhary, S.5
Forsyth, C.6
Farhadi, A.7
Keshavarzian, A.8
-
56
-
-
0344465840
-
Potential role of MCP-1 in endothelial cell tight junction opening: signaling via Rho and Rho kinase
-
Stamatovic S.M., Keep R.F., Kunkel S.L., Andjelkovic A.V. Potential role of MCP-1 in endothelial cell tight junction opening: signaling via Rho and Rho kinase. J. Cell Sci. 2003, 116:4615-4628.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 4615-4628
-
-
Stamatovic, S.M.1
Keep, R.F.2
Kunkel, S.L.3
Andjelkovic, A.V.4
-
58
-
-
67650306418
-
Protein phosphatase 2A plays a role in hydrogen peroxide-induced disruption of tight junctions in Caco-2 cell monolayers
-
Sheth P., Samak G., Shull J., Seth A., Rao R. Protein phosphatase 2A plays a role in hydrogen peroxide-induced disruption of tight junctions in Caco-2 cell monolayers. Biochem. J. 2009, 421:59-70.
-
(2009)
Biochem. J.
, vol.421
, pp. 59-70
-
-
Sheth, P.1
Samak, G.2
Shull, J.3
Seth, A.4
Rao, R.5
-
59
-
-
0034599992
-
Pores in the wall: claudins constitute tight junction strands containing aqueous pores
-
Tsukita S., Furuse M. Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J. Cell Biol. 2000, 149:13-16.
-
(2000)
J. Cell Biol.
, vol.149
, pp. 13-16
-
-
Tsukita, S.1
Furuse, M.2
-
60
-
-
79959876473
-
Mechanism and consequence of chitosan-mediated reversible epithelial tight junction opening
-
Yeh T.H., Hsu L.W., Tseng M.T., Lee P.L., Sonjae K., Ho Y.C., Sung H.W. Mechanism and consequence of chitosan-mediated reversible epithelial tight junction opening. Biomaterials 2011, 32:6164-6173.
-
(2011)
Biomaterials
, vol.32
, pp. 6164-6173
-
-
Yeh, T.H.1
Hsu, L.W.2
Tseng, M.T.3
Lee, P.L.4
Sonjae, K.5
Ho, Y.C.6
Sung, H.W.7
-
61
-
-
84860726458
-
Opening of epithelial tight junctions and enhancement of paracellular permeation by chitosan: microscopic, ultra-structural and computed-tomographic observations
-
Sonaje K., Chuang E.Y., Lin K.J., Yen T.C., Su F.Y., Tseng M.T., Sung H.W. Opening of epithelial tight junctions and enhancement of paracellular permeation by chitosan: microscopic, ultra-structural and computed-tomographic observations. Mol. Pharm. 2012, 10.1021/mp200572t.
-
(2012)
Mol. Pharm.
-
-
Sonaje, K.1
Chuang, E.Y.2
Lin, K.J.3
Yen, T.C.4
Su, F.Y.5
Tseng, M.T.6
Sung, H.W.7
-
62
-
-
33646085268
-
PH and cd measurements on a fully deacetylated chitosan: application to CuII-polymer interactions
-
Domard A. pH and cd measurements on a fully deacetylated chitosan: application to CuII-polymer interactions. Int. J. Biol. Macromol. 1987, 9:98-104.
-
(1987)
Int. J. Biol. Macromol.
, vol.9
, pp. 98-104
-
-
Domard, A.1
-
63
-
-
0025954040
-
(B) Mechanisms of peptide and protein absorption: (1) paracellular intestinal transport: modulation of absorption
-
Nellans H.N. (B) Mechanisms of peptide and protein absorption: (1) paracellular intestinal transport: modulation of absorption. Adv. Drug Deliv. Rev. 1991, 7:339-364.
-
(1991)
Adv. Drug Deliv. Rev.
, vol.7
, pp. 339-364
-
-
Nellans, H.N.1
-
64
-
-
0029102179
-
Passive diffusion of weak organic electrolytes across Caco-2 cell monolayers: uncoupling the contributions of hydrodynamic, transcellular, and paracellular barriers
-
Adson A., Burton P.S., Raub T.J., Barsuhn C.L., Audus K.L., Ho N.F. Passive diffusion of weak organic electrolytes across Caco-2 cell monolayers: uncoupling the contributions of hydrodynamic, transcellular, and paracellular barriers. J. Pharm. Sci. 1995, 84:1197-1204.
-
(1995)
J. Pharm. Sci.
, vol.84
, pp. 1197-1204
-
-
Adson, A.1
Burton, P.S.2
Raub, T.J.3
Barsuhn, C.L.4
Audus, K.L.5
Ho, N.F.6
-
65
-
-
60849130683
-
In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery
-
Sonaje K., Lin Y.H., Juang J.H., Wey S.P., Chen C.T., Sung H.W. In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery. Biomaterials 2009, 30:2329-2339.
-
(2009)
Biomaterials
, vol.30
, pp. 2329-2339
-
-
Sonaje, K.1
Lin, Y.H.2
Juang, J.H.3
Wey, S.P.4
Chen, C.T.5
Sung, H.W.6
-
66
-
-
78249241188
-
Self-assembled pH-sensitive nanoparticles: a platform for oral delivery of protein drugs
-
Sonaje K., Lin K.J., Wang J.J., Mi F.L., Chen C.T., Juang J.H., Sung H.W. Self-assembled pH-sensitive nanoparticles: a platform for oral delivery of protein drugs. Adv. Funct. Mater. 2010, 20:3695-3700.
-
(2010)
Adv. Funct. Mater.
, vol.20
, pp. 3695-3700
-
-
Sonaje, K.1
Lin, K.J.2
Wang, J.J.3
Mi, F.L.4
Chen, C.T.5
Juang, J.H.6
Sung, H.W.7
-
67
-
-
75149149000
-
Chitosan-based hydrogels for controlled, localized drug delivery
-
Bhattarai N., Gunn J., Zhang M. Chitosan-based hydrogels for controlled, localized drug delivery. Adv. Drug Deliv. Rev. 2010, 62:83-99.
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 83-99
-
-
Bhattarai, N.1
Gunn, J.2
Zhang, M.3
-
68
-
-
79955478547
-
Chitosan-A versatile semi-synthetic polymer in biomedical applications
-
Dash M., Chiellini F., Ottenbrite R., Chiellini E. Chitosan-A versatile semi-synthetic polymer in biomedical applications. Prog. Polym. Sci. 2011, 36:981-1014.
-
(2011)
Prog. Polym. Sci.
, vol.36
, pp. 981-1014
-
-
Dash, M.1
Chiellini, F.2
Ottenbrite, R.3
Chiellini, E.4
-
69
-
-
33746474818
-
Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan-a review
-
George M., Abraham T.E. Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan-a review. J. Control. Release 2006, 114:1-14.
-
(2006)
J. Control. Release
, vol.114
, pp. 1-14
-
-
George, M.1
Abraham, T.E.2
-
70
-
-
4444246205
-
Chemically modified chitin and chitosan as biomaterials
-
Sashiwa H., Aiba S. Chemically modified chitin and chitosan as biomaterials. Prog. Polym. Sci. 2004, 29:887-908.
-
(2004)
Prog. Polym. Sci.
, vol.29
, pp. 887-908
-
-
Sashiwa, H.1
Aiba, S.2
-
71
-
-
0033007333
-
Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: in vitro evaluation in intestinal epithelial cells (Caco-2)
-
Kotzé A.F., Thanou M.M., Lueben H.L., De Boer A., Verhoef J., Junginger H.E. Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: in vitro evaluation in intestinal epithelial cells (Caco-2). J. Pharm. Sci. 1999, 88:253-257.
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 253-257
-
-
Kotzé, A.F.1
Thanou, M.M.2
Lueben, H.L.3
De Boer, A.4
Verhoef, J.5
Junginger, H.E.6
-
72
-
-
42649142580
-
Nanoparticles of quaternized chitosan derivatives as a carrier for colon delivery of insulin: ex vivo and in vivo studies
-
Bayat A., Dorkoosh F.A., Dehpour A.R., Moezi L., Larijani B., Junginger H.E., Rafiee-Tehrani M. Nanoparticles of quaternized chitosan derivatives as a carrier for colon delivery of insulin: ex vivo and in vivo studies. Int. J. Pharm. 2008, 356:259-266.
-
(2008)
Int. J. Pharm.
, vol.356
, pp. 259-266
-
-
Bayat, A.1
Dorkoosh, F.A.2
Dehpour, A.R.3
Moezi, L.4
Larijani, B.5
Junginger, H.E.6
Rafiee-Tehrani, M.7
-
73
-
-
33344467489
-
Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system
-
Amidi M., Romeijn S.G., Borchard G., Junginger H.E., Hennink W.E., Jiskoot W. Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system. J. Control. Release 2006, 111:107-116.
-
(2006)
J. Control. Release
, vol.111
, pp. 107-116
-
-
Amidi, M.1
Romeijn, S.G.2
Borchard, G.3
Junginger, H.E.4
Hennink, W.E.5
Jiskoot, W.6
-
74
-
-
45749109076
-
Oral delivery of peptide drugs using nanoparticles self-assembled by poly(γ-glutamic acid) and a chitosan derivative functionalized by trimethylation
-
Mi F.L., Wu Y.Y., Lin Y.H., Sonaje K., Ho Y.C., Chen C.T., Juang J.H., Sung H.W. Oral delivery of peptide drugs using nanoparticles self-assembled by poly(γ-glutamic acid) and a chitosan derivative functionalized by trimethylation. Bioconjug. Chem. 2008, 19:1248-1255.
-
(2008)
Bioconjug. Chem.
, vol.19
, pp. 1248-1255
-
-
Mi, F.L.1
Wu, Y.Y.2
Lin, Y.H.3
Sonaje, K.4
Ho, Y.C.5
Chen, C.T.6
Juang, J.H.7
Sung, H.W.8
-
75
-
-
83355173904
-
Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport
-
Jin Y., Song Y., Zhu X., Zhou D., Chen C., Zhang Z., Huang Y. Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport. Biomaterials 2012, 33:1573-1582.
-
(2012)
Biomaterials
, vol.33
, pp. 1573-1582
-
-
Jin, Y.1
Song, Y.2
Zhu, X.3
Zhou, D.4
Chen, C.5
Zhang, Z.6
Huang, Y.7
-
76
-
-
33750351790
-
Chitosan graft copolymer nanoparticles for oral protein drug delivery: preparation and characterization
-
Qian F., Cui F., Ding J., Tang C., Yin C. Chitosan graft copolymer nanoparticles for oral protein drug delivery: preparation and characterization. Biomacromolecules 2006, 7:2722-2727.
-
(2006)
Biomacromolecules
, vol.7
, pp. 2722-2727
-
-
Qian, F.1
Cui, F.2
Ding, J.3
Tang, C.4
Yin, C.5
-
77
-
-
44449154695
-
Preparation and characterization of insulin nanoparticles using chitosan and its quaternized derivatives
-
Bayat A., Larijani B., Ahmadian S., Junginger H.E., Rafiee-Tehrani M. Preparation and characterization of insulin nanoparticles using chitosan and its quaternized derivatives. Nanomed. Nanotechnol. 2008, 4:115-120.
-
(2008)
Nanomed. Nanotechnol.
, vol.4
, pp. 115-120
-
-
Bayat, A.1
Larijani, B.2
Ahmadian, S.3
Junginger, H.E.4
Rafiee-Tehrani, M.5
-
78
-
-
50249129610
-
Permeation enhancer effect of chitosan and chitosan derivatives: comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells
-
Sadeghi A., Dorkoosh F., Avadi M., Weinhold M., Bayat A., Delie F., Gurny R., Larijani B., Rafiee-Tehrani M., Junginger H. Permeation enhancer effect of chitosan and chitosan derivatives: comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells. Eur. J. Pharm. Biopharm. 2008, 70:270-278.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, pp. 270-278
-
-
Sadeghi, A.1
Dorkoosh, F.2
Avadi, M.3
Weinhold, M.4
Bayat, A.5
Delie, F.6
Gurny, R.7
Larijani, B.8
Rafiee-Tehrani, M.9
Junginger, H.10
-
79
-
-
33747620727
-
Synthesis of N, N-dimethyl N-ethyl chitosan as a carrier for oral delivery of peptide drugs
-
Bayat A., Sadeghi A., Avadi M., Amini M., Rafiee-Tehrani M., Shafiee A., Majlesi R., Junginger H. Synthesis of N, N-dimethyl N-ethyl chitosan as a carrier for oral delivery of peptide drugs. J. Bioact. Compat. Polym. 2006, 21:433-444.
-
(2006)
J. Bioact. Compat. Polym.
, vol.21
, pp. 433-444
-
-
Bayat, A.1
Sadeghi, A.2
Avadi, M.3
Amini, M.4
Rafiee-Tehrani, M.5
Shafiee, A.6
Majlesi, R.7
Junginger, H.8
-
80
-
-
15044364588
-
Diethyl methyl chitosan as an intestinal paracellular enhancer: ex vivo and in vivo studies
-
Avadi M., Jalali A., Sadeghi A., Shamimi K., Bayati K., Nahid E., Dehpour A., Rafiee-Tehrani M. Diethyl methyl chitosan as an intestinal paracellular enhancer: ex vivo and in vivo studies. Int. J. Pharm. 2005, 293:83-89.
-
(2005)
Int. J. Pharm.
, vol.293
, pp. 83-89
-
-
Avadi, M.1
Jalali, A.2
Sadeghi, A.3
Shamimi, K.4
Bayati, K.5
Nahid, E.6
Dehpour, A.7
Rafiee-Tehrani, M.8
-
81
-
-
41349110165
-
Preparation, characterization and antibacterial activities of chitosan, N-trimethyl chitosan (TMC) and N-diethylmethyl chitosan (DEMC) nanoparticles loaded with insulin using both the ionotropic gelation and polyelectrolyte complexation methods
-
Sadeghi A.M.M., Dorkoosh F., Avadi M., Saadat P., Rafiee-Tehrani M., Junginger H. Preparation, characterization and antibacterial activities of chitosan, N-trimethyl chitosan (TMC) and N-diethylmethyl chitosan (DEMC) nanoparticles loaded with insulin using both the ionotropic gelation and polyelectrolyte complexation methods. Int. J. Pharm. 2008, 355:299-306.
-
(2008)
Int. J. Pharm.
, vol.355
, pp. 299-306
-
-
Sadeghi, A.M.M.1
Dorkoosh, F.2
Avadi, M.3
Saadat, P.4
Rafiee-Tehrani, M.5
Junginger, H.6
-
82
-
-
77954819727
-
In vitro permeability enhancement in intestinal epithelial cells (Caco-2) monolayer of water soluble quaternary ammonium chitosan derivatives
-
Kowapradit J., Opanasopit P., Ngawhirunpat T., Apirakaramwong A., Rojanarata T., Ruktanonchai U., Sajomsang W. In vitro permeability enhancement in intestinal epithelial cells (Caco-2) monolayer of water soluble quaternary ammonium chitosan derivatives. AAPS PharmSciTech 2010, 11:497-508.
-
(2010)
AAPS PharmSciTech
, vol.11
, pp. 497-508
-
-
Kowapradit, J.1
Opanasopit, P.2
Ngawhirunpat, T.3
Apirakaramwong, A.4
Rojanarata, T.5
Ruktanonchai, U.6
Sajomsang, W.7
-
83
-
-
0035859963
-
Quaternary ammonium palmitoyl glycol chitosan-a new polysoap for drug delivery
-
Uchegbu I.F., Sadiq L., Arastoo M., Gray A.I., Wang W., Waigh R.D., Schätzleinä A.G. Quaternary ammonium palmitoyl glycol chitosan-a new polysoap for drug delivery. Int. J. Pharm. 2001, 224:185-199.
-
(2001)
Int. J. Pharm.
, vol.224
, pp. 185-199
-
-
Uchegbu, I.F.1
Sadiq, L.2
Arastoo, M.3
Gray, A.I.4
Wang, W.5
Waigh, R.D.6
Schätzleinä, A.G.7
-
84
-
-
84855435709
-
Enhanced oral absorption of hydrophobic and hydrophilic drugs using quaternary ammonium palmitoyl glycol chitosan nanoparticles
-
Siew A., Le H., Thiovolet M., Schätzlein A., Gellert P., Uchegbu I. Enhanced oral absorption of hydrophobic and hydrophilic drugs using quaternary ammonium palmitoyl glycol chitosan nanoparticles. Mol. Pharm. 2012, 9:14-28.
-
(2012)
Mol. Pharm.
, vol.9
, pp. 14-28
-
-
Siew, A.1
Le, H.2
Thiovolet, M.3
Schätzlein, A.4
Gellert, P.5
Uchegbu, I.6
-
85
-
-
11144297274
-
Chitosan chemistry and pharmaceutical perspectives
-
Kumar M.N.V.R., Muzzarelli R.A.A., Muzzarelli C., Sashiwa H., Domb A.J. Chitosan chemistry and pharmaceutical perspectives. Chem. Rev. 2004, 104:6017-6084.
-
(2004)
Chem. Rev.
, vol.104
, pp. 6017-6084
-
-
Kumar, M.N.V.R.1
Muzzarelli, R.A.A.2
Muzzarelli, C.3
Sashiwa, H.4
Domb, A.J.5
-
86
-
-
26644452975
-
Thiomers: a new generation of mucoadhesive polymers
-
Bernkop-Schnürch A. Thiomers: a new generation of mucoadhesive polymers. Adv. Drug Deliv. Rev. 2005, 57:1569-1582.
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 1569-1582
-
-
Bernkop-Schnürch, A.1
-
87
-
-
0034925740
-
Thiolated polymers-thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates
-
Kast C.E., Bernkop-Schnürch A. Thiolated polymers-thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates. Biomaterials 2001, 22:2345-2352.
-
(2001)
Biomaterials
, vol.22
, pp. 2345-2352
-
-
Kast, C.E.1
Bernkop-Schnürch, A.2
-
88
-
-
57349184053
-
Chitosan-NAC nanoparticles as a vehicle for nasal absorption enhancement of insulin
-
Wang X., Zheng C., Wu Z., Teng D., Zhang X., Wang Z., Li C. Chitosan-NAC nanoparticles as a vehicle for nasal absorption enhancement of insulin. J. Biomed. Mater. Res. B Appl. Biomater. 2009, 88:150-161.
-
(2009)
J. Biomed. Mater. Res. B Appl. Biomater.
, vol.88
, pp. 150-161
-
-
Wang, X.1
Zheng, C.2
Wu, Z.3
Teng, D.4
Zhang, X.5
Wang, Z.6
Li, C.7
-
89
-
-
24044555891
-
Synthesis and in vitro evaluation of a novel chitosan-glutathione conjugate
-
Kafedjiiski K., Föger F., Werle M., Bernkop-Schnürch A. Synthesis and in vitro evaluation of a novel chitosan-glutathione conjugate. Pharm. Res. 2005, 22:1480-1488.
-
(2005)
Pharm. Res.
, vol.22
, pp. 1480-1488
-
-
Kafedjiiski, K.1
Föger, F.2
Werle, M.3
Bernkop-Schnürch, A.4
-
90
-
-
33646159752
-
In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan
-
Föger F., Schmitz T., Bernkop-Schnürch A. In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan. Biomaterials 2006, 27:4250-4255.
-
(2006)
Biomaterials
, vol.27
, pp. 4250-4255
-
-
Föger, F.1
Schmitz, T.2
Bernkop-Schnürch, A.3
-
91
-
-
4444265622
-
Synthesis and in vitro evaluation of a novel thiolated chitosan
-
Kafedjiiski K., Krauland A.H., Hoffer M.H., Bernkop-Schnürch A. Synthesis and in vitro evaluation of a novel thiolated chitosan. Biomaterials 2005, 26:819-826.
-
(2005)
Biomaterials
, vol.26
, pp. 819-826
-
-
Kafedjiiski, K.1
Krauland, A.H.2
Hoffer, M.H.3
Bernkop-Schnürch, A.4
-
92
-
-
24044501942
-
Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate
-
Kafedjiiski K., Hoffer M., Werle M., Bernkop-Schnürch A. Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate. Biomaterials 2006, 27:127-135.
-
(2006)
Biomaterials
, vol.27
, pp. 127-135
-
-
Kafedjiiski, K.1
Hoffer, M.2
Werle, M.3
Bernkop-Schnürch, A.4
-
93
-
-
0042140521
-
Thiolated polymers: evidence for the formation of disulphide bonds with mucus glycoproteins
-
Leitner V.M., Walker G.F., Bernkop-Schnürch A. Thiolated polymers: evidence for the formation of disulphide bonds with mucus glycoproteins. Eur. J. Pharm. Biopharm. 2003, 56:207-214.
-
(2003)
Eur. J. Pharm. Biopharm.
, vol.56
, pp. 207-214
-
-
Leitner, V.M.1
Walker, G.F.2
Bernkop-Schnürch, A.3
-
94
-
-
34447287587
-
Characterization of chitosan thiolation and application to thiol quantification onto nanoparticle surface
-
Bravo-Osuna I., Teutonico D., Arpicco S., Vauthier C., Ponchel G. Characterization of chitosan thiolation and application to thiol quantification onto nanoparticle surface. Int. J. Pharm. 2007, 340:173-181.
-
(2007)
Int. J. Pharm.
, vol.340
, pp. 173-181
-
-
Bravo-Osuna, I.1
Teutonico, D.2
Arpicco, S.3
Vauthier, C.4
Ponchel, G.5
-
95
-
-
23744465756
-
The use of thiolated polymers as carrier matrix in oral peptide delivery-proof of concept
-
Bernkop-Schnürch A., Pinter Y., Guggi D., Kahlbacher H., Schöffmann G., Schuh M., Schmerold I., Del Curto M.D., D'Antonio M., Esposito P. The use of thiolated polymers as carrier matrix in oral peptide delivery-proof of concept. J. Control. Release 2005, 106:26-33.
-
(2005)
J. Control. Release
, vol.106
, pp. 26-33
-
-
Bernkop-Schnürch, A.1
Pinter, Y.2
Guggi, D.3
Kahlbacher, H.4
Schöffmann, G.5
Schuh, M.6
Schmerold, I.7
Del Curto, M.D.8
D'Antonio, M.9
Esposito, P.10
-
96
-
-
79953242692
-
Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa
-
Dunnhaupt S., Barthelmes J., Hombach J., Sakloetsakun D., Arkhipova V., Bernkop-Schnurch A. Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa. Int. J. Pharm. 2011, 408:191-199.
-
(2011)
Int. J. Pharm.
, vol.408
, pp. 191-199
-
-
Dunnhaupt, S.1
Barthelmes, J.2
Hombach, J.3
Sakloetsakun, D.4
Arkhipova, V.5
Bernkop-Schnurch, A.6
-
97
-
-
77956631702
-
Thiol functionalized polymethacrylic acid-based hydrogel microparticles for oral insulin delivery
-
Sajeesh S., Vauthier C., Gueutin C., Ponchel G., Sharma C.P. Thiol functionalized polymethacrylic acid-based hydrogel microparticles for oral insulin delivery. Acta Biomater. 2010, 6:3072-3080.
-
(2010)
Acta Biomater.
, vol.6
, pp. 3072-3080
-
-
Sajeesh, S.1
Vauthier, C.2
Gueutin, C.3
Ponchel, G.4
Sharma, C.P.5
-
98
-
-
34250159823
-
Chitosan-thioglycolic acid conjugate: an alternative carrier for oral nonviral gene delivery?
-
Martien R., Loretz B., Thaler M., Majzoob S., Bernkop-Schnürch A. Chitosan-thioglycolic acid conjugate: an alternative carrier for oral nonviral gene delivery?. J. Biomed. Mater. Res. A 2007, 82:1-9.
-
(2007)
J. Biomed. Mater. Res. A
, vol.82
, pp. 1-9
-
-
Martien, R.1
Loretz, B.2
Thaler, M.3
Majzoob, S.4
Bernkop-Schnürch, A.5
-
99
-
-
48549107174
-
Polymeric enhancers of mucosal epithelia permeability: synthesis, transepithelial penetration-enhancing properties, mechanism of action, safety issues
-
Di Colo G., Zambito Y., Zaino C. Polymeric enhancers of mucosal epithelia permeability: synthesis, transepithelial penetration-enhancing properties, mechanism of action, safety issues. J. Pharm. Sci. 2008, 97:1652-1680.
-
(2008)
J. Pharm. Sci.
, vol.97
, pp. 1652-1680
-
-
Di Colo, G.1
Zambito, Y.2
Zaino, C.3
-
100
-
-
77953808647
-
Thiolated trimethyl chitosan nanocomplexes as gene carriers with high in vitro and in vivo transfection efficiency
-
Zhao X., Yin L., Ding J., Tang C., Gu S., Yin C., Mao Y. Thiolated trimethyl chitosan nanocomplexes as gene carriers with high in vitro and in vivo transfection efficiency. J. Control. Release 2010, 144:46-54.
-
(2010)
J. Control. Release
, vol.144
, pp. 46-54
-
-
Zhao, X.1
Yin, L.2
Ding, J.3
Tang, C.4
Gu, S.5
Yin, C.6
Mao, Y.7
-
101
-
-
77954143772
-
Novel carboxymethyl derivatives of chitin and chitosan materials and their biomedical applications
-
Jayakumar R., Prabaharan M., Nair S., Tokura S., Tamura H., Selvamurugan N. Novel carboxymethyl derivatives of chitin and chitosan materials and their biomedical applications. Prog. Mater. Sci. 2010, 55:675-709.
-
(2010)
Prog. Mater. Sci.
, vol.55
, pp. 675-709
-
-
Jayakumar, R.1
Prabaharan, M.2
Nair, S.3
Tokura, S.4
Tamura, H.5
Selvamurugan, N.6
-
102
-
-
0035252008
-
Antibacterial action of chitosan and carboxymethylated chitosan
-
Fei Liu X., Lin Guan Y., Zhi Yang D., Li Z., De Yao K. Antibacterial action of chitosan and carboxymethylated chitosan. J. Appl. Polym. Sci. 2001, 79:1324-1335.
-
(2001)
J. Appl. Polym. Sci.
, vol.79
, pp. 1324-1335
-
-
Fei Liu, X.1
Lin Guan, Y.2
Zhi Yang, D.3
Li, Z.4
De Yao, K.5
-
103
-
-
34948860159
-
Nanoparticles incorporated in bilaminated films: a smart drug delivery system for oral formulations
-
Cui F., He C., Yin L., Qian F., He M., Tang C., Yin C. Nanoparticles incorporated in bilaminated films: a smart drug delivery system for oral formulations. Biomacromolecules 2007, 8:2845-2850.
-
(2007)
Biomacromolecules
, vol.8
, pp. 2845-2850
-
-
Cui, F.1
He, C.2
Yin, L.3
Qian, F.4
He, M.5
Tang, C.6
Yin, C.7
-
104
-
-
66149083634
-
Preparation, characterization, and oral delivery of insulin loaded carboxylated chitosan grafted poly (methyl methacrylate) nanoparticles
-
Cui F., Qian F., Zhao Z., Yin L., Tang C., Yin C. Preparation, characterization, and oral delivery of insulin loaded carboxylated chitosan grafted poly (methyl methacrylate) nanoparticles. Biomacromolecules 2009, 10:1253-1258.
-
(2009)
Biomacromolecules
, vol.10
, pp. 1253-1258
-
-
Cui, F.1
Qian, F.2
Zhao, Z.3
Yin, L.4
Tang, C.5
Yin, C.6
-
105
-
-
0242352525
-
N-acylated chitosan: hydrophobic matrices for controlled drug release
-
Le Tien C., Lacroix M., Ispas-Szabo P., Mateescu M.A. N-acylated chitosan: hydrophobic matrices for controlled drug release. J. Control. Release 2003, 93:1-13.
-
(2003)
J. Control. Release
, vol.93
, pp. 1-13
-
-
Le Tien, C.1
Lacroix, M.2
Ispas-Szabo, P.3
Mateescu, M.A.4
-
106
-
-
46549086982
-
The aggregative behavior of hydrophobically modified chitosans with high substitution degree in aqueous solution
-
Ortona O., D'Errico G., Mangiapia G., Ciccarelli D. The aggregative behavior of hydrophobically modified chitosans with high substitution degree in aqueous solution. Carbohydr. Polym. 2008, 74:16-22.
-
(2008)
Carbohydr. Polym.
, vol.74
, pp. 16-22
-
-
Ortona, O.1
D'Errico, G.2
Mangiapia, G.3
Ciccarelli, D.4
-
107
-
-
65249164789
-
Biodegradable nanoparticles based on linoleic acid and poly(β-malic acid) double grafted chitosan derivatives as carriers of anticancer drugs
-
Zhao Z., He M., Yin L., Bao J., Shi L., Wang B., Tang C., Yin C. Biodegradable nanoparticles based on linoleic acid and poly(β-malic acid) double grafted chitosan derivatives as carriers of anticancer drugs. Biomacromolecules 2009, 10:565-572.
-
(2009)
Biomacromolecules
, vol.10
, pp. 565-572
-
-
Zhao, Z.1
He, M.2
Yin, L.3
Bao, J.4
Shi, L.5
Wang, B.6
Tang, C.7
Yin, C.8
-
108
-
-
77952692576
-
Cholesterol succinyl chitosan anchored liposomes: preparation, characterization, physical stability, and drug release behavior
-
Wang Y., Tu S., Li R., Yang X.Y., Liu L., Zhang Q. Cholesterol succinyl chitosan anchored liposomes: preparation, characterization, physical stability, and drug release behavior. Nanomed. Nanotechnol. 2010, 6:471-477.
-
(2010)
Nanomed. Nanotechnol.
, vol.6
, pp. 471-477
-
-
Wang, Y.1
Tu, S.2
Li, R.3
Yang, X.Y.4
Liu, L.5
Zhang, Q.6
-
109
-
-
41549087356
-
Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin
-
Hu F.Q., Wu X., Du Y.Z., You J., Yuan H. Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin. Eur. J. Pharm. Biopharm. 2008, 69:117-125.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.69
, pp. 117-125
-
-
Hu, F.Q.1
Wu, X.2
Du, Y.Z.3
You, J.4
Yuan, H.5
-
110
-
-
75149147998
-
Targeted delivery of low molecular drugs using chitosan and its derivatives
-
Park J.H., Saravanakumar G., Kim K., Kwon I.C. Targeted delivery of low molecular drugs using chitosan and its derivatives. Adv. Drug Deliv. Rev. 2010, 62:28-41.
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 28-41
-
-
Park, J.H.1
Saravanakumar, G.2
Kim, K.3
Kwon, I.C.4
-
111
-
-
33645968393
-
Trends in muco-adhesive analysis
-
Harding S.E. Trends in muco-adhesive analysis. Trends Food Sci. Technol. 2006, 17:255-262.
-
(2006)
Trends Food Sci. Technol.
, vol.17
, pp. 255-262
-
-
Harding, S.E.1
-
112
-
-
62849083225
-
Synthesis and evaluation of lauryl succinyl chitosan particles towards oral insulin delivery and absorption
-
Rekha M., Sharma C.P. Synthesis and evaluation of lauryl succinyl chitosan particles towards oral insulin delivery and absorption. J. Control. Release 2009, 135:144-151.
-
(2009)
J. Control. Release
, vol.135
, pp. 144-151
-
-
Rekha, M.1
Sharma, C.P.2
-
113
-
-
0000053810
-
Mucin layers on hydrophobic surfaces studied with ellipsometry and surface force measurements
-
Malmsten M., Blomberg E., Claesson P., Carlstedt I., Ljusegren I. Mucin layers on hydrophobic surfaces studied with ellipsometry and surface force measurements. J. Colloid Interface Sci. 1992, 151:579-590.
-
(1992)
J. Colloid Interface Sci.
, vol.151
, pp. 579-590
-
-
Malmsten, M.1
Blomberg, E.2
Claesson, P.3
Carlstedt, I.4
Ljusegren, I.5
-
114
-
-
0033991816
-
Chitosan and its derivatives: potential excipients for peroral peptide delivery systems
-
Bernkop-Schnürch A. Chitosan and its derivatives: potential excipients for peroral peptide delivery systems. Int. J. Pharm. 2000, 194:1-13.
-
(2000)
Int. J. Pharm.
, vol.194
, pp. 1-13
-
-
Bernkop-Schnürch, A.1
-
115
-
-
0032473473
-
The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins
-
Bernkop-Schnürch A. The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins. J. Control. Release 1998, 52:1-16.
-
(1998)
J. Control. Release
, vol.52
, pp. 1-16
-
-
Bernkop-Schnürch, A.1
-
116
-
-
0026505270
-
Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells
-
Citi S. Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells. J. cell Biol. 1992, 117:169-178.
-
(1992)
J. cell Biol.
, vol.117
, pp. 169-178
-
-
Citi, S.1
-
117
-
-
0142020885
-
Regulation of adherens junctions and epithelial paracellular permeability: a novel function for polyamines
-
Guo X., Rao J.N., Liu L., Zou T.T., Turner D.J., Bass B.L., Wang J.Y. Regulation of adherens junctions and epithelial paracellular permeability: a novel function for polyamines. Am. J. Physiol. Cell Physiol. 2003, 285:C1174-C1187.
-
(2003)
Am. J. Physiol. Cell Physiol.
, vol.285
-
-
Guo, X.1
Rao, J.N.2
Liu, L.3
Zou, T.T.4
Turner, D.J.5
Bass, B.L.6
Wang, J.Y.7
-
118
-
-
43049175030
-
Chitosan-modifications and applications: opportunities galore
-
Mourya V., Inamdar N.N. Chitosan-modifications and applications: opportunities galore. React. Funct. Polym. 2008, 68:1013-1051.
-
(2008)
React. Funct. Polym.
, vol.68
, pp. 1013-1051
-
-
Mourya, V.1
Inamdar, N.N.2
-
119
-
-
0031915514
-
Synthesis and in vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteins
-
Bernkop-Schnürch A., Scerbe-Saiko A. Synthesis and in vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteins. Pharm. Res. 1998, 15:263-269.
-
(1998)
Pharm. Res.
, vol.15
, pp. 263-269
-
-
Bernkop-Schnürch, A.1
Scerbe-Saiko, A.2
-
120
-
-
0032472305
-
Mucoadhesive polymers as platforms for peroral peptide delivery and absorption: synthesis and evaluation of different chitosan-EDTA conjugates
-
Bernkop-Schnürch A., Krajicek M.E. Mucoadhesive polymers as platforms for peroral peptide delivery and absorption: synthesis and evaluation of different chitosan-EDTA conjugates. J. Control. Release 1998, 50:215-223.
-
(1998)
J. Control. Release
, vol.50
, pp. 215-223
-
-
Bernkop-Schnürch, A.1
Krajicek, M.E.2
-
121
-
-
26944452043
-
PEGylation, successful approach to drug delivery
-
Veronese F.M., Pasut G. PEGylation, successful approach to drug delivery. Drug Discov. Today 2005, 10:1451-1458.
-
(2005)
Drug Discov. Today
, vol.10
, pp. 1451-1458
-
-
Veronese, F.M.1
Pasut, G.2
-
122
-
-
80052067468
-
A novel method for synthesizing PEGylated chitosan nanoparticles: strategy, preparation, and in vitro analysis
-
Malhotra M., Lane C., Tomaro-Duchesneau C., Saha S., Prakash S. A novel method for synthesizing PEGylated chitosan nanoparticles: strategy, preparation, and in vitro analysis. Int. J. Nanomedicine 2011, 6:485-494.
-
(2011)
Int. J. Nanomedicine
, vol.6
, pp. 485-494
-
-
Malhotra, M.1
Lane, C.2
Tomaro-Duchesneau, C.3
Saha, S.4
Prakash, S.5
-
123
-
-
84859602944
-
Formulation and in vitro characterization of PEGylated chitosan and polyethylene imine polymers with thrombospondin-I gene bearing pDNA
-
Mehmet Saka O., Bozkir A. Formulation and in vitro characterization of PEGylated chitosan and polyethylene imine polymers with thrombospondin-I gene bearing pDNA. J. Biomed. Mater. Res. B Appl. Biomater. 2012, 100:984-992.
-
(2012)
J. Biomed. Mater. Res. B Appl. Biomater.
, vol.100
, pp. 984-992
-
-
Mehmet Saka, O.1
Bozkir, A.2
-
124
-
-
79954420700
-
Recent advancement of chitosan-based nanoparticles for oral controlled delivery of insulin and other therapeutic agents
-
Chaudhury A., Das S. Recent advancement of chitosan-based nanoparticles for oral controlled delivery of insulin and other therapeutic agents. AAPS PharmSciTech 2011, 12:10-20.
-
(2011)
AAPS PharmSciTech
, vol.12
, pp. 10-20
-
-
Chaudhury, A.1
Das, S.2
-
125
-
-
71649103464
-
The role of mucoadhesion of trimethyl chitosan and PEGylated trimethyl chitosan nanocomplexes in insulin uptake
-
Jintapattanakit A., Junyaprasert V.B., Kissel T. The role of mucoadhesion of trimethyl chitosan and PEGylated trimethyl chitosan nanocomplexes in insulin uptake. J. Pharm. Sci. 2009, 98:4818-4830.
-
(2009)
J. Pharm. Sci.
, vol.98
, pp. 4818-4830
-
-
Jintapattanakit, A.1
Junyaprasert, V.B.2
Kissel, T.3
-
126
-
-
80053937972
-
Effect of PEGylation on the diffusion and stability of chitosan-DNA polyplexes in collagen gels
-
Lelu S., Strand S.P., Steine J., Davies C.L. Effect of PEGylation on the diffusion and stability of chitosan-DNA polyplexes in collagen gels. Biomacromolecules 2011, 12:3656-3665.
-
(2011)
Biomacromolecules
, vol.12
, pp. 3656-3665
-
-
Lelu, S.1
Strand, S.P.2
Steine, J.3
Davies, C.L.4
-
127
-
-
33645241398
-
Chitosan-PEG nanocapsules as new carriers for oral peptide delivery: effect of chitosan PEGylation degree
-
Prego C., Torres D., Fernandez-Megia E., Novoa-Carballal R., Quinoa E., Alonso M. Chitosan-PEG nanocapsules as new carriers for oral peptide delivery: effect of chitosan PEGylation degree. J. Control. Release 2006, 111:299-308.
-
(2006)
J. Control. Release
, vol.111
, pp. 299-308
-
-
Prego, C.1
Torres, D.2
Fernandez-Megia, E.3
Novoa-Carballal, R.4
Quinoa, E.5
Alonso, M.6
-
128
-
-
20444441841
-
Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers
-
Mao S., Shuai X., Unger F., Wittmar M., Xie X., Kissel T. Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers. Biomaterials 2005, 26:6343-6356.
-
(2005)
Biomaterials
, vol.26
, pp. 6343-6356
-
-
Mao, S.1
Shuai, X.2
Unger, F.3
Wittmar, M.4
Xie, X.5
Kissel, T.6
-
129
-
-
18244365849
-
Protein drug stability: a formulation challenge
-
Frokjaer S., Otzen D.E. Protein drug stability: a formulation challenge. Nat. Rev. Drug Discov. 2005, 4:298-306.
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 298-306
-
-
Frokjaer, S.1
Otzen, D.E.2
-
130
-
-
0036105205
-
Development of oral insulin: progress and current status
-
Gordon Still J. Development of oral insulin: progress and current status. Diabetes Metab. Res. Rev. 2002, 18:S29-S37.
-
(2002)
Diabetes Metab. Res. Rev.
, vol.18
-
-
Gordon Still, J.1
-
131
-
-
47049095564
-
Strategies toward the improved oral delivery of insulin nanoparticles via gastrointestinal uptake and translocation
-
Woitiski C.B., Carvalho R.A., Ribeiro A.J., Neufeld R.J., Veiga F. Strategies toward the improved oral delivery of insulin nanoparticles via gastrointestinal uptake and translocation. BioDrugs 2008, 22:223-237.
-
(2008)
BioDrugs
, vol.22
, pp. 223-237
-
-
Woitiski, C.B.1
Carvalho, R.A.2
Ribeiro, A.J.3
Neufeld, R.J.4
Veiga, F.5
-
132
-
-
33846543799
-
Oral delivery of insulin associated to polymeric nanoparticles in diabetic rats
-
Damgé C., Maincent P., Ubrich N. Oral delivery of insulin associated to polymeric nanoparticles in diabetic rats. J. Control. Release 2007, 117:163-170.
-
(2007)
J. Control. Release
, vol.117
, pp. 163-170
-
-
Damgé, C.1
Maincent, P.2
Ubrich, N.3
-
133
-
-
4344640503
-
The physiological rationale for oral insulin administration
-
Arbit E. The physiological rationale for oral insulin administration. Diabetes Technol. Ther. 2004, 6:510-517.
-
(2004)
Diabetes Technol. Ther.
, vol.6
, pp. 510-517
-
-
Arbit, E.1
-
134
-
-
84855967689
-
Protease inhibition and absorption enhancement by functional nanoparticles for effective oral insulin delivery
-
Su F.Y., Lin K.J., Sonaje K., Wey S.P., Yen T.C., Ho Y.C., Panda N., Chuang E.Y., Maiti B., Sung H.W. Protease inhibition and absorption enhancement by functional nanoparticles for effective oral insulin delivery. Biomaterials 2012, 33:2801-2811.
-
(2012)
Biomaterials
, vol.33
, pp. 2801-2811
-
-
Su, F.Y.1
Lin, K.J.2
Sonaje, K.3
Wey, S.P.4
Yen, T.C.5
Ho, Y.C.6
Panda, N.7
Chuang, E.Y.8
Maiti, B.9
Sung, H.W.10
-
135
-
-
22244488749
-
Oral delivery of peptide drugs: barriers and developments
-
Hamman J.H., Enslin G.M., Kotze A.F. Oral delivery of peptide drugs: barriers and developments. BioDrugs 2005, 19:165-177.
-
(2005)
BioDrugs
, vol.19
, pp. 165-177
-
-
Hamman, J.H.1
Enslin, G.M.2
Kotze, A.F.3
-
136
-
-
76749103819
-
Enteric-coated capsules filled with freeze-dried chitosan/poly ([gamma]-glutamic acid) nanoparticles for oral insulin delivery
-
Sonaje K., Chen Y.J., Chen H.L., Wey S.P., Juang J.H., Nguyen H.N., Hsu C.W., Lin K.J., Sung H.W. Enteric-coated capsules filled with freeze-dried chitosan/poly ([gamma]-glutamic acid) nanoparticles for oral insulin delivery. Biomaterials 2010, 31:3384-3394.
-
(2010)
Biomaterials
, vol.31
, pp. 3384-3394
-
-
Sonaje, K.1
Chen, Y.J.2
Chen, H.L.3
Wey, S.P.4
Juang, J.H.5
Nguyen, H.N.6
Hsu, C.W.7
Lin, K.J.8
Sung, H.W.9
-
137
-
-
77954385916
-
Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: oral delivery using pH-Responsive nanoparticles vs. subcutaneous injection
-
Sonaje K., Lin K.J., Wey S.P., Lin C.K., Yeh T.H., Nguyen H.N., Hsu C.W., Yen T.C., Juang J.H., Sung H.W. Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: oral delivery using pH-Responsive nanoparticles vs. subcutaneous injection. Biomaterials 2010, 31:6849-6858.
-
(2010)
Biomaterials
, vol.31
, pp. 6849-6858
-
-
Sonaje, K.1
Lin, K.J.2
Wey, S.P.3
Lin, C.K.4
Yeh, T.H.5
Nguyen, H.N.6
Hsu, C.W.7
Yen, T.C.8
Juang, J.H.9
Sung, H.W.10
-
138
-
-
35848959714
-
Alginate/chitosan nanoparticles are effective for oral insulin delivery
-
Sarmento B., Ribeiro A., Veiga F., Sampaio P., Neufeld R., Ferreira D. Alginate/chitosan nanoparticles are effective for oral insulin delivery. Pharm. Res. 2007, 24:2198-2206.
-
(2007)
Pharm. Res.
, vol.24
, pp. 2198-2206
-
-
Sarmento, B.1
Ribeiro, A.2
Veiga, F.3
Sampaio, P.4
Neufeld, R.5
Ferreira, D.6
-
139
-
-
80053313377
-
Recent advances of chitosan nanoparticles as drug carriers
-
Wang J.J., Zeng Z.W., Xiao R.Z., Xie T., Zhou G.L., Zhan X.R., Wang S.L. Recent advances of chitosan nanoparticles as drug carriers. Int. J. Nanomedicine 2011, 6:765-774.
-
(2011)
Int. J. Nanomedicine
, vol.6
, pp. 765-774
-
-
Wang, J.J.1
Zeng, Z.W.2
Xiao, R.Z.3
Xie, T.4
Zhou, G.L.5
Zhan, X.R.6
Wang, S.L.7
-
140
-
-
39449092067
-
Thiolated chitosans: useful excipients for oral drug delivery
-
Werle M., Bernkop-Schnürch A. Thiolated chitosans: useful excipients for oral drug delivery. J. Pharm. Pharmacol. 2008, 60:273-281.
-
(2008)
J. Pharm. Pharmacol.
, vol.60
, pp. 273-281
-
-
Werle, M.1
Bernkop-Schnürch, A.2
-
141
-
-
0348026751
-
In vivo evaluation of an oral salmon calcitonin-delivery system based on a thiolated chitosan carrier matrix
-
Guggi D., Kast C.E., Bernkop-Schnürch A. In vivo evaluation of an oral salmon calcitonin-delivery system based on a thiolated chitosan carrier matrix. Pharm. Res. 2003, 20:1989-1994.
-
(2003)
Pharm. Res.
, vol.20
, pp. 1989-1994
-
-
Guggi, D.1
Kast, C.E.2
Bernkop-Schnürch, A.3
-
142
-
-
0034456212
-
Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
-
Szayna M., Doyle M.E., Betkey J.A., Holloway H.W., Spencer R.G.S., Greig N.H., Egan J.M. Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats. Endocrinology 2000, 141:1936-1941.
-
(2000)
Endocrinology
, vol.141
, pp. 1936-1941
-
-
Szayna, M.1
Doyle, M.E.2
Betkey, J.A.3
Holloway, H.W.4
Spencer, R.G.S.5
Greig, N.H.6
Egan, J.M.7
-
143
-
-
42649110672
-
Pharmacokinetics and pharmacodynamics of exenatide following alternate routes of administration
-
Gedulin B.R., Smith P.A., Jodka C.M., Chen K., Bhavsar S., Nielsen L.L., Parkes D.G., Young A.A. Pharmacokinetics and pharmacodynamics of exenatide following alternate routes of administration. Int. J. Pharm. 2008, 356:231-238.
-
(2008)
Int. J. Pharm.
, vol.356
, pp. 231-238
-
-
Gedulin, B.R.1
Smith, P.A.2
Jodka, C.M.3
Chen, K.4
Bhavsar, S.5
Nielsen, L.L.6
Parkes, D.G.7
Young, A.A.8
-
144
-
-
33644803761
-
Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice
-
Ding X., Saxena N.K., Lin S., Gupta N., Anania F.A. Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice. Hepatology 2006, 43:173-181.
-
(2006)
Hepatology
, vol.43
, pp. 173-181
-
-
Ding, X.1
Saxena, N.K.2
Lin, S.3
Gupta, N.4
Anania, F.A.5
-
145
-
-
69249195769
-
Exenatide efficacy and safety: a systematic review
-
Norris S., Lee N., Thakurta S., Chan B. Exenatide efficacy and safety: a systematic review. Diabet. Med. 2009, 26:837-846.
-
(2009)
Diabet. Med.
, vol.26
, pp. 837-846
-
-
Norris, S.1
Lee, N.2
Thakurta, S.3
Chan, B.4
-
146
-
-
47249091822
-
Salmon calcitonin: a review of current and future therapeutic indications
-
Chesnut C., Azria M., Silverman S., Engelhardt M., Olson M., Mindeholm L. Salmon calcitonin: a review of current and future therapeutic indications. Osteoporos. Int. 2008, 19:479-491.
-
(2008)
Osteoporos. Int.
, vol.19
, pp. 479-491
-
-
Chesnut, C.1
Azria, M.2
Silverman, S.3
Engelhardt, M.4
Olson, M.5
Mindeholm, L.6
-
147
-
-
0029450581
-
25years of salmon calcitonin: from synthesis to therapeutic use
-
Azria M., Copp D., Zanelli J. 25years of salmon calcitonin: from synthesis to therapeutic use. Calcif. Tissue Int. 1995, 57:405-408.
-
(1995)
Calcif. Tissue Int.
, vol.57
, pp. 405-408
-
-
Azria, M.1
Copp, D.2
Zanelli, J.3
-
148
-
-
0026034777
-
Cyclosporin metabolism by the gastrointestinal mucosa
-
Tjia J., Webber I., Back D. Cyclosporin metabolism by the gastrointestinal mucosa. J. Clin. Pharmacol. 1991, 31:344-346.
-
(1991)
J. Clin. Pharmacol.
, vol.31
, pp. 344-346
-
-
Tjia, J.1
Webber, I.2
Back, D.3
-
149
-
-
0037027833
-
Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A
-
El-Shabouri M. Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A. Int. J. Pharm. 2002, 249:101-108.
-
(2002)
Int. J. Pharm.
, vol.249
, pp. 101-108
-
-
El-Shabouri, M.1
-
150
-
-
22144447455
-
Design and development of polymers for gene delivery
-
Pack D.W., Hoffman A.S., Pun S., Stayton P.S. Design and development of polymers for gene delivery. Nat. Rev. Drug Discov. 2005, 4:581-593.
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 581-593
-
-
Pack, D.W.1
Hoffman, A.S.2
Pun, S.3
Stayton, P.S.4
-
151
-
-
77957298626
-
Enhancement of efficiencies of the cellular uptake and gene silencing of chitosan/siRNA complexes via the inclusion of a negatively charged poly[gamma]-glutamic acid
-
Liao Z.X., Ho Y.C., Chen H.L., Peng S.F., Hsiao C.W., Sung H.W. Enhancement of efficiencies of the cellular uptake and gene silencing of chitosan/siRNA complexes via the inclusion of a negatively charged poly[gamma]-glutamic acid. Biomaterials 2010, 31:8780-8788.
-
(2010)
Biomaterials
, vol.31
, pp. 8780-8788
-
-
Liao, Z.X.1
Ho, Y.C.2
Chen, H.L.3
Peng, S.F.4
Hsiao, C.W.5
Sung, H.W.6
-
152
-
-
33846456199
-
Amino ester glycol urethane
-
Tseng S.J., Tang S.C. Synthesis and characterization of the novel transfection reagent poly. Biomacromolecules 2007, 8:50-58.
-
(2007)
Biomacromolecules
, vol.8
, pp. 50-58
-
-
Tseng, S.J.1
Tang, S.C.2
-
153
-
-
83655192126
-
Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery
-
Zhou J., Liu J., Cheng C.J., Patel T.R., Weller C.E., Piepmeier J.M., Jiang Z., Saltzman W.M. Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery. Nat. Mater. 2011, 11:82-90.
-
(2011)
Nat. Mater.
, vol.11
, pp. 82-90
-
-
Zhou, J.1
Liu, J.2
Cheng, C.J.3
Patel, T.R.4
Weller, C.E.5
Piepmeier, J.M.6
Jiang, Z.7
Saltzman, W.M.8
-
154
-
-
84856587267
-
Mechanistic study of transfection of chitosan/DNA complexes coated by anionic poly(γ-glutamic acid)
-
Liao Z.X., Peng S.F., Ho Y.C., Mi F.L., Maiti B., Sung H.W. Mechanistic study of transfection of chitosan/DNA complexes coated by anionic poly(γ-glutamic acid). Biomaterials 2012, 3306-3315.
-
(2012)
Biomaterials
, pp. 3306-3315
-
-
Liao, Z.X.1
Peng, S.F.2
Ho, Y.C.3
Mi, F.L.4
Maiti, B.5
Sung, H.W.6
-
155
-
-
84855795348
-
Efficient GLP-1 gene delivery using two-step transcription amplification plasmid system with a secretion signal peptide and arginine-grafted bioreducible polymer
-
Kim T., Lee M., Kim S.W. Efficient GLP-1 gene delivery using two-step transcription amplification plasmid system with a secretion signal peptide and arginine-grafted bioreducible polymer. J. Control. Release 2012, 157:243-248.
-
(2012)
J. Control. Release
, vol.157
, pp. 243-248
-
-
Kim, T.1
Lee, M.2
Kim, S.W.3
-
156
-
-
44549084568
-
Electrostatic immobilization of DNA polyplexes on small intestinal submucosa for tissue substrate-mediated transfection
-
Tseng S., Chuang C.J., Tang S.C. Electrostatic immobilization of DNA polyplexes on small intestinal submucosa for tissue substrate-mediated transfection. Acta Biomater. 2008, 4:799-807.
-
(2008)
Acta Biomater.
, vol.4
, pp. 799-807
-
-
Tseng, S.1
Chuang, C.J.2
Tang, S.C.3
-
157
-
-
80055005101
-
Self-organized nanoparticles prepared by guanidine-and disulfide-modified chitosan as a gene delivery carrier
-
Ho Y.C., Liao Z.X., Panda N., Tang D.W., Yu S.H., Mi F.L., Sung H.W. Self-organized nanoparticles prepared by guanidine-and disulfide-modified chitosan as a gene delivery carrier. J. Mater. Chem. 2011, 21:16918-16927.
-
(2011)
J. Mater. Chem.
, vol.21
, pp. 16918-16927
-
-
Ho, Y.C.1
Liao, Z.X.2
Panda, N.3
Tang, D.W.4
Yu, S.H.5
Mi, F.L.6
Sung, H.W.7
-
158
-
-
75149133614
-
Chitosan-based formulations for delivery of DNA and siRNA
-
Mao S., Sun W., Kissel T. Chitosan-based formulations for delivery of DNA and siRNA. Adv. Drug Deliv. Rev. 2010, 62:12-27.
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 12-27
-
-
Mao, S.1
Sun, W.2
Kissel, T.3
-
159
-
-
34447306055
-
PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination
-
Garinot M., Fiévez V., Pourcelle V., Stoffelbach F., Des Rieux A., Plapied L., Theate I., Freichels H., JérÔme C., Marchand-Brynaert J. PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination. J. Control. Release 2007, 120:195-204.
-
(2007)
J. Control. Release
, vol.120
, pp. 195-204
-
-
Garinot, M.1
Fiévez, V.2
Pourcelle, V.3
Stoffelbach, F.4
Des Rieux, A.5
Plapied, L.6
Theate, I.7
Freichels, H.8
JérÔme, C.9
Marchand-Brynaert, J.10
-
160
-
-
0028798530
-
Uptake and transport of copolymer biodegradable microspheres by rabbit Peyer's patch M cells
-
Ermak T.H., Dougherty E.P., Bhagat H.R., Kabok Z., Pappo J. Uptake and transport of copolymer biodegradable microspheres by rabbit Peyer's patch M cells. Cell Tissue Res. 1995, 279:433-436.
-
(1995)
Cell Tissue Res.
, vol.279
, pp. 433-436
-
-
Ermak, T.H.1
Dougherty, E.P.2
Bhagat, H.R.3
Kabok, Z.4
Pappo, J.5
-
161
-
-
0035144059
-
Chitosan microparticles for oral vaccination: preparation, characterization and preliminary in vivo uptake studies in murine Peyer's patches
-
Van der Lubben I., Verhoef J., Van Aelst A., Borchard G., Junginger H. Chitosan microparticles for oral vaccination: preparation, characterization and preliminary in vivo uptake studies in murine Peyer's patches. Biomaterials 2001, 22:687-694.
-
(2001)
Biomaterials
, vol.22
, pp. 687-694
-
-
Van der Lubben, I.1
Verhoef, J.2
Van Aelst, A.3
Borchard, G.4
Junginger, H.5
-
162
-
-
0027869836
-
Comparison of poly(DL-lactide-co-glycolide) and polystyrene microsphere targeting to intestinal M cells
-
Jepson M., Simmons N., O'hagan D., Hirst B. Comparison of poly(DL-lactide-co-glycolide) and polystyrene microsphere targeting to intestinal M cells. J. Drug Target. 1993, 1:245-249.
-
(1993)
J. Drug Target.
, vol.1
, pp. 245-249
-
-
Jepson, M.1
Simmons, N.2
O'hagan, D.3
Hirst, B.4
-
163
-
-
0030465871
-
The intestinal uptake of particles and the implications for drug and antigen delivery
-
O'hagan D. The intestinal uptake of particles and the implications for drug and antigen delivery. J. Anat. 1996, 189:477-482.
-
(1996)
J. Anat.
, vol.189
, pp. 477-482
-
-
O'hagan, D.1
-
164
-
-
0035801903
-
Mechanism of cell transfection with plasmid/chitosan complexes
-
Ishii T., Okahata Y., Sato T. Mechanism of cell transfection with plasmid/chitosan complexes. Biochim. Biophys. Acta 2001, 1514:51-64.
-
(2001)
Biochim. Biophys. Acta
, vol.1514
, pp. 51-64
-
-
Ishii, T.1
Okahata, Y.2
Sato, T.3
-
165
-
-
0346685833
-
Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles
-
Chen J., Yang W.L., Li G., Qian J., Xue J.L., Fu S.K., Lu D.R. Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles. World J. Gastroenterol. 2004, 10:112-116.
-
(2004)
World J. Gastroenterol.
, vol.10
, pp. 112-116
-
-
Chen, J.1
Yang, W.L.2
Li, G.3
Qian, J.4
Xue, J.L.5
Fu, S.K.6
Lu, D.R.7
-
166
-
-
0032928470
-
Gene expression in space
-
Hammond T., Lewis F., Goodwin T., Linnehan R., Wolf D., Hire K., Campbell W., Benes E., O'Reilly K., Globus R. Gene expression in space. Nat. Med. 1999, 5:359.
-
(1999)
Nat. Med.
, vol.5
, pp. 359
-
-
Hammond, T.1
Lewis, F.2
Goodwin, T.3
Linnehan, R.4
Wolf, D.5
Hire, K.6
Campbell, W.7
Benes, E.8
O'Reilly, K.9
Globus, R.10
-
167
-
-
56949084718
-
Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles
-
Bowman K., Sarkar R., Raut S., Leong K.W. Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles. J. Control. Release 2008, 132:252-259.
-
(2008)
J. Control. Release
, vol.132
, pp. 252-259
-
-
Bowman, K.1
Sarkar, R.2
Raut, S.3
Leong, K.W.4
-
169
-
-
28444477001
-
Chitosan microparticles containing plasmid DNA as potential oral gene delivery system
-
Guliyeva U., Oner F., Ozsoy S., Haziroǧlu R. Chitosan microparticles containing plasmid DNA as potential oral gene delivery system. Eur. J. Pharm. Biopharm. 2006, 62:17-25.
-
(2006)
Eur. J. Pharm. Biopharm.
, vol.62
, pp. 17-25
-
-
Guliyeva, U.1
Oner, F.2
Ozsoy, S.3
Haziroǧlu, R.4
-
170
-
-
0038513487
-
Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice
-
Chew J.L., Wolfowicz C.B., Mao H.Q., Leong K.W., Chua K.Y. Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice. Vaccine 2003, 21:2720-2729.
-
(2003)
Vaccine
, vol.21
, pp. 2720-2729
-
-
Chew, J.L.1
Wolfowicz, C.B.2
Mao, H.Q.3
Leong, K.W.4
Chua, K.Y.5
-
171
-
-
0035805579
-
Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence
-
Chuang Y.J., Swanson R., Raja S.M., Olson S.T. Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. J. Biol. Chem. 2001, 276:14961-14971.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14961-14971
-
-
Chuang, Y.J.1
Swanson, R.2
Raja, S.M.3
Olson, S.T.4
-
172
-
-
0032552897
-
Oral delivery of anticoagulant doses of heparin: a randomized, double-blind, controlled study in humans
-
Baughman R.A., Kapoor S.C., Agarwal R.K., Kisicki J., Catella-Lawson F., FitzGerald G.A. Oral delivery of anticoagulant doses of heparin: a randomized, double-blind, controlled study in humans. Circulation 1998, 98:1610-1615.
-
(1998)
Circulation
, vol.98
, pp. 1610-1615
-
-
Baughman, R.A.1
Kapoor, S.C.2
Agarwal, R.K.3
Kisicki, J.4
Catella-Lawson, F.5
FitzGerald, G.A.6
-
173
-
-
32044444307
-
Oral delivery of chemical conjugates of heparin and deoxycholic acid in aqueous formulation
-
Kim S.K., Vaishali B., Lee E., Lee S., Lee Y., Kumar T.S., Moon H.T., Byun Y. Oral delivery of chemical conjugates of heparin and deoxycholic acid in aqueous formulation. Thromb. Res. 2006, 117:419-427.
-
(2006)
Thromb. Res.
, vol.117
, pp. 419-427
-
-
Kim, S.K.1
Vaishali, B.2
Lee, E.3
Lee, S.4
Lee, Y.5
Kumar, T.S.6
Moon, H.T.7
Byun, Y.8
|